PFRMAT SS TARGET T0187 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0187.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0187.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0187.t2k.str.rdb (weight 1.53983) METHOD T0187.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0187.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 29 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 29 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.str.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 29 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 29 METHOD METHOD ============================================ MODEL 1 L C 0.91 K C 0.89 K C 0.88 P C 0.64 A E 0.85 A E 0.92 L E 0.92 I E 0.86 F E 0.56 G C 0.82 G C 0.87 E C 0.66 T E 0.56 V E 0.74 V E 0.87 H E 0.89 V E 0.79 K E 0.55 G C 0.70 N C 0.83 G C 0.84 I C 0.85 G C 0.87 G C 0.79 R C 0.49 N H 0.72 Q H 0.92 E H 0.94 L H 0.95 A H 0.96 L H 0.96 S H 0.95 A H 0.95 A H 0.95 I H 0.94 A H 0.90 L H 0.83 E H 0.55 G C 0.77 I C 0.86 E C 0.85 G C 0.88 V E 0.54 I E 0.83 L E 0.91 C E 0.90 S E 0.85 A E 0.65 G C 0.62 T C 0.74 D C 0.78 G C 0.82 T C 0.79 D C 0.80 G C 0.85 P C 0.74 T C 0.66 D C 0.56 A C 0.52 A C 0.64 G C 0.64 G E 0.57 I E 0.73 V E 0.54 D C 0.78 G C 0.50 S H 0.63 T H 0.80 A H 0.94 K H 0.94 T H 0.95 L H 0.94 K H 0.93 A H 0.82 M C 0.61 G C 0.90 E C 0.90 D C 0.86 P H 0.89 Y H 0.93 Q H 0.94 Y H 0.93 L H 0.87 K H 0.72 N H 0.57 N C 0.64 D C 0.69 S H 0.74 Y H 0.92 N H 0.94 A H 0.94 L H 0.94 K H 0.92 K H 0.81 S H 0.59 G C 0.60 A C 0.62 L C 0.37 L E 0.59 I E 0.59 T C 0.48 G C 0.83 P C 0.85 T C 0.84 G C 0.83 T C 0.77 N C 0.63 V C 0.54 N C 0.55 D E 0.52 L E 0.71 I E 0.78 I E 0.83 G E 0.85 L E 0.81 I E 0.67 V C 0.89 END