a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0187 TM1585, T. maritima
- gi|16265133|ref|NP_437925.1|_199:355 (NC_003078) putative hydroxypyruvate reductase protein [Sinorhizobium meliloti]
- gi|15141272|emb|CAC49785.1| (AL603646) putative hydroxypyruvate reductase protein [Sinorhizobium meliloti]
- gi|15644333|ref|NP_229385.1|_201:350 (NC_000853) glycerate kinase, putative [Thermotoga maritima]
- gi|7462843|pir||A72236 hypothetical protein TM1585 - Thermotoga maritima (strain MSB8)
- gi|4982155|gb|AAD36652.1|AE001803_5 (AE001803) glycerate kinase, putative [Thermotoga maritima]
- gi|18976396|ref|NP_577753.1|_223:383 (NC_003413) putative glycerate kinase [Pyrococcus furiosus DSM 3638]
- gi|18891922|gb|AAL80148.1| (AE010128) putative glycerate kinase [Pyrococcus furiosus DSM 3638]
- gi|17549668|ref|NP_523008.1|_217:373 (NC_003296) PROBABLE HYDROXYPYRUVATE REDUCTASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
- gi|17431922|emb|CAD18600.1| (AL646084) PROBABLE HYDROXYPYRUVATE REDUCTASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
- gi|17987853|ref|NP_540487.1|_178:335 (NC_003317) PUTATIVE HYDROXYPYRUVATE REDUCTASE [Brucella melitensis]
- gi|17983583|gb|AAL52751.1| (AE009592) PUTATIVE HYDROXYPYRUVATE REDUCTASE [Brucella melitensis]
- gi|13474290|ref|NP_105858.1|_198:354 (NC_002678) hypothetical protein [Mesorhizobium loti]
- gi|14025042|dbj|BAB51644.1| (AP003005) hypothetical protein [Mesorhizobium loti]
- gi|16119561|ref|NP_396267.1|_199:354 (NC_003064) AGR_pAT_bx66p [Agrobacterium tumefaciens] [Agrobacterium tumefaciens str. C58 (Cereon)]
- gi|17938918|ref|NP_535706.1| (NC_003306) hydroxypyruvate reductase [Agrobacterium tumefaciens str. C58 (Dupont)] [Agrobacterium tumefaciens str. C58 (U. Washington)]
- gi|15162117|gb|AAK90708.1| (AE007902) AGR_pAT_bx66p [Agrobacterium tumefaciens str. C58 (Cereon)]
- gi|17743779|gb|AAL46022.1| (AE008955) hydroxypyruvate reductase [Agrobacterium tumefaciens str. C58 (U. Washington)]
- gi|15967047|ref|NP_387400.1|_230:388 (NC_003047) PUTATIVE HYDROXYPYRUVATE REDUCTASE PROTEIN [Sinorhizobium meliloti]
- gi|15076320|emb|CAC47873.1| (AL591793) PUTATIVE HYDROXYPYRUVATE REDUCTASE PROTEIN [Sinorhizobium meliloti]
- gi|15596696|ref|NP_250190.1|_197:352 (NC_002516) conserved hypothetical protein [Pseudomonas aeruginosa]
- gi|11347789|pir||E83459 conserved hypothetical protein PA1499 [imported] - Pseudomonas aeruginosa (strain PAO1)
- gi|9947454|gb|AAG04888.1|AE004578_10 (AE004578) conserved hypothetical protein [Pseudomonas aeruginosa]
- gi|14590403|ref|NP_142469.1|_208:367 (NC_000961) hypothetical protein [Pyrococcus horikoshii]
- gi|7518673|pir||B71162 hypothetical protein PH0495 - Pyrococcus horikoshii
- gi|3256900|dbj|BAA29583.1| (AP000002) 440aa long hypothetical protein [Pyrococcus horikoshii]
- gi|19388000|gb|AAH25834.1|_255:451 (BC025834) similar to hypothetical protein [Mus musculus]
- gi|19684145|gb|AAH25935.1| (BC025935) similar to hypothetical protein [Mus musculus]
- gi|21620001|gb|AAH33063.1| (BC033063) Unknown (protein for MGC:37851) [Mus musculus]
- gi|18312544|ref|NP_559211.1|_218:375 (NC_003364) conserved hypothetical protein [Pyrobaculum aerophilum]
- gi|18160010|gb|AAL63393.1| (AE009815) conserved hypothetical protein [Pyrobaculum aerophilum]
- gi|20894723|ref|XP_135143.1|_255:451 (XM_135143) similar to CG9886 gene product [Mus musculus]
- gi|21314996|gb|AAH30732.1|_128:324 (BC030732) Unknown (protein for MGC:37913) [Mus musculus]
- gi|14521745|ref|NP_127221.1|_203:362 (NC_000868) hypothetical protein [Pyrococcus abyssi]
- gi|7518011|pir||E75001 hypothetical protein PAB1021 - Pyrococcus abyssi (strain Orsay)
- gi|5458965|emb|CAB50451.1| (AJ248288) hypothetical protein [Pyrococcus abyssi]
- gi|15891700|ref|NP_357372.1|_205:359 (NC_003063) AGR_L_3166p [Agrobacterium tumefaciens] [Agrobacterium tumefaciens str. C58 (Cereon)]
- gi|15160156|gb|AAK90157.1| (AE008360) AGR_L_3166p [Agrobacterium tumefaciens str. C58 (Cereon)]
- gi|21315005|gb|AAH30736.1|_95:291 (BC030736) Unknown (protein for IMAGE:5132880) [Mus musculus]
- gi|21687104|ref|NP_660305.1|_189:385 (NM_145262) similar to CG9886 gene product [Homo sapiens]
- gi|18256912|gb|AAH21896.1|AAH21896 (BC021896) Unknown (protein for MGC:9528) [Homo sapiens]
- gi|17936943|ref|NP_533732.1|_202:356 (NC_003305) hydroxypyruvate reductase [Agrobacterium tumefaciens str. C58 (U. Washington)]
- gi|17741611|gb|AAL44048.1| (AE009253) hydroxypyruvate reductase [Agrobacterium tumefaciens str. C58 (U. Washington)]
- gi|13676533|dbj|BAB41180.1|_128:324 (AB060262) hypothetical protein [Macaca fascicularis]
- gi|16263221|ref|NP_436014.1|_197:352 (NC_003037) putative TtuD3 hydroxypyruvate reductase [Sinorhizobium meliloti]
- gi|14523892|gb|AAK65426.1| (AE007264) putative TtuD3 hydroxypyruvate reductase [Sinorhizobium meliloti]
- gi|4033482 sp|P70788|TUD3_AGRVI_164:318 Putative hydroxypyruvate reductase
- gi|984369|gb|AAB61624.1| (U32375) enzyme degrading primary tartrate degradation product [Rhizobium vitis]
- gi|14601127|ref|NP_147655.1|_158:323 (NC_000854) hypothetical protein [Aeropyrum pernix]
- gi|7516171|pir||D72697 hypothetical protein APE0996 - Aeropyrum pernix (strain K1)
- gi|5104665|dbj|BAA79980.1| (AP000060) 400aa long hypothetical protein [Aeropyrum pernix]
- gi|4033487 sp|Q44472|TUD4_AGRVI_217:371 Putative hydroxypyruvate reductase
- gi|805293|gb|AAA68699.1| (U25634) putative hydroxypyruvate reductase; inducible by tartrate; Method: conceptual translation supplied by author [Rhizobium vitis]
- gi|1585264|prf||2124372D ttuD gene [Rhizobium vitis]
- gi|1907334|gb|AAB66496.1|_214:366 (U87316) putative glycerate kinase [Methylobacterium extorquens]
- gi|21542484 sp|Q09235|YQ42_CAEEL_156:327 Hypothetical protein C13B9.2 in chromosome III
- gi|20198777|gb|AAA62515.2| (U21309) Hypothetical protein C13B9.2 [Caenorhabditis elegans]
- gi|17552152|ref|NP_498462.1|_122:293 (NM_066061) C13B9.2.p [Caenorhabditis elegans]
- gi|17545205|ref|NP_518607.1|_202:365 (NC_003295) PUTATIVE HYDROXYPYRUVATE REDUCTASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
- gi|17427496|emb|CAD14014.1| (AL646059) PUTATIVE HYDROXYPYRUVATE REDUCTASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
- gi|15897575|ref|NP_342180.1|_194:337 (NC_002754) Glycerate kinase, putative [Sulfolobus solfataricus]
- gi|6015809|emb|CAB57636.1| (Y18930) hypothetical protein [Sulfolobus solfataricus]
- gi|13813834|gb|AAK40970.1| (AE006694) Glycerate kinase, putative [Sulfolobus solfataricus]
- gi|21300335|gb|EAA12480.1|_278:474 (AAAB01008964) agCP11255 [Anopheles gambiae str. PEST]
- gi|19920578|ref|NP_608684.1|_229:415 (NM_134840) CG9886 gene product [Drosophila melanogaster]
- gi|7295954|gb|AAF51252.1| (AE003583) CG9886 gene product [Drosophila melanogaster]
- gi|16769768|gb|AAL29103.1| (AY061555) LP09309p [Drosophila melanogaster]
- gi|22405563|gb|ZP_00000441.1|_211:356 (NZ_AAAA01000043) hypothetical protein [Ferroplasma acidarmanus]
- gi|13541614|ref|NP_111302.1|_212:353 (NC_002689) Predicted glycerate kinase [Thermoplasma volcanium]
- gi|14325013|dbj|BAB59939.1| (AP000993) glycerate kinase [Thermoplasma volcanium]
- gi|16082522|ref|NP_393931.1|_212:353 (NC_002578) Predicted glycerate kinase [Thermoplasma acidophilum]
- gi|10639623|emb|CAC11595.1|_189:330 (AL445064) glycerate kinase related protein [Thermoplasma acidophilum]
- gi|15922355|ref|NP_378024.1|_195:329 (NC_003106) 399aa long conserved hypothetical protein [Sulfolobus tokodaii]
- gi|15623144|dbj|BAB67133.1| (AP000988) 399aa long conserved hypothetical protein [Sulfolobus tokodaii]
- gi|15807636|ref|NP_294881.1|_192:309 (NC_001263) hydroxypyruvate reductase, putative [Deinococcus radiodurans]
- gi|18676755|dbj|BAB85018.1|_128:212 (AK074215) unnamed protein product [Homo sapiens]

                     10        20          30             40        50 
                     |         |           |              |         | 
   1 GPAW.....PDSS..TSEDALKVLEKYGIE..TSESVKRAIL.....QETPKHLSNVEIHLIGNV
   2 GPTI.....ADAA..SREDALKIVERYRLA..LPEKVMRWLAsa7apRPSDPRFARNEVRLIASA
   3 GPAW.....PDSS..TSEDALKVLEKYGIE..TSESVKRAIL.....QETPKHLSNVEIHLIGNV
   4 GPTV.....KDPT..TFRDAYRILKLYNLWdkIPESVRRYIElg8veETLKEDLPNVHNFLIASN
   5 GPTV.....ADPT..TRDDALAVLARYRVA..VPASVLAHLRgd7siKPGDVRLRASTVRLITAP
   6 GPTV.....PDET..SRDEALKIIERYRLD..LPQAALAHIKse7apQPDDGVFARNEVRVIASA
   7 GPTV.....PDTG..SREDALASISAYGMK..LPASVMAHINsp7apDPGDERFSRNEVHLIASA
   8 GPTV.....LSRS..TPQDALRVIDRYGMA..LPDHVIRHLQda6gmDPDHPCFDNNQVTVIASP
   9 GPTV.....ADRS..SLEEAREIVARYAIA..LPERVTAHLAsd7apRPDDAAFAGNEVHVIASA
  10 GPSV.....GDPT..TSADALAILKRYAID..VPQNVLDWLAdp7tvKPDDPCLARSHFQLIATP
  11 GPTV.....KDPT..TFEDAKRILELYDIWekVPESVRLHIErg8veETLKEDLPNVHNFLIASN
  12 GPTV.....ASAH..SVQDCLHILNHYGLRaaLPRSVKTVLSradsdPHGPHTCGHVLNVIIGSN
  13 GPTA.....PDGT..SREFAIRVLKKYGIWgeLPPRIRAVFEgg6tvKEGDALLAKVQNVIVANN
  14 GPTV.....ASTH..SVQDCLHILNHYGLRaaLPRSVKTVLSradsdPHGPHTCGHVLNVIIGSN
  15 GPTV.....ASAH..SVQDCLHILNHYGLRaaLPRSVKTVLSradsdPHGPHTCGHVLNVIIGSN
  16 GPTV.....KDPT..TFQDAKRILELYGIWdrVPESVRSHIEkg8aeETLKEELPNIHNFLIASN
  17 GPTV.....ADPS..DIATVREIVARYGLD..LPETVRKVLEkge..ETPKSGDIEEDVRMIAAP
  18 GPTV.....ASAH..SVQDCLHILNHYGLRaaLPRSVKTVLSradsdPHGPHTCGHVLNVIIGSN
  19 GPTV.....ASSH..NVQDCLHILNRYGLRaaLPRSVKTVLSradsdPHGPHTCGHVLNVIIGSN
  20 GPTV.....ADPS..DIATVREIVARYGLD..LPETVRKVLEkge..ETPKSGDIEEDVRMIAAP
  21 GPTV.....ASSH..SVQDCLHILNRYGLRaaLPRSVKTVLSradsdPHGPRTCGHVLNVIIGSN
  22 GPTV.....PDAT..DRAAARAMRDAWRIE..LPERLVDWLKge7apSPNDPVFAGHEVQVIASA
  23 GPTV.....ANDT..TIDDAREIVSRYRLV..LPPAAQDVLAngg..ARNCTGKVSSDVRMIASP
  24 GPTV.....PDPT..TYGDALAVLERYGLRdsAPPRVVALLEa11tpKPGDRRLSTTENRLAASN
  25 GPTV.....ADPT..TLADAAAIIARYGID..LPESARAVLVqgn..ETPKAGEVAGEIRLVAAP
  26 GPTV.....PDPS..TLADARAICERRGIS..LPESALALLNdp7tpKAGDPAFARAEYRIIARP
  27 GPTVipahqQDKF..IISNILESLKINKLE..LPVNVKNVLEnhek.EQLPENTSRFQNFIISSN
  28 GPTVipahqQDKF..IISNILESLKINKLE..LPVNVKNVLEnhek.EQLPENTSRFQNFIISSN
  29 GPTV.....PDPS..TYADALAILARWGAQ..APESVRAHLEr11tpKPGDACFARVANHVIATA
  30 GLTS.....IDNS..SNDDALEILKAIGL-..--EKYSKYLT.....ETPKSFSRIVKNYIILDN
  31 GPTV.....IQKGvaVNGKAKEILEKYGLWskLPDSILKVIEqpt..VREVKETYNNDLFLLGSN
  32 GPTI.....QPEA..-AASPSDILKKHHVWeeLSPEIRRVFEqpe..EQKNTSLPEHKVFVVGSN
  33 GPLVnvp..APAN..LKELAKKYIKDNRLR..DIIEKVDISE.....TLDSKYFTNVKNTIVLKN
  34 GPLA.....ENKL..---DPSAVYAKYRDI..IPIDITKYVEns...SIEDLYFRNVMNRIILSN
  35 GPLS.....ENKL..---DPVAVYERFRNV..IGVDIERFLKta...QIEDEYFRKVQTRIVLSN
  36 GPLS.....ENKL..---DPVAVYERFRNV..IGVDIERFLKta...QIEDEYFRKVQTRIVLSN
  37 GPTL.....PDSS..TVDDAKLILNKVGL-..---GEYSKYL.....IETKKEVHNSFNFLILDI
  38 GPTV.....PDPT..TFADALAVLEKYSIA..APAVRAHFQSga...PDTPDTLPHVTNEIIGSN
  39 GPTV.....ASSH..NVQDCLHILNRYGLRaaLPRSVKTVLSradsdPHGPHTCGHVLNVIIGSN


             60        70        80        90       100            110 
             |         |         |         |         |              | 
   1 QKVCDEAKSLAKEKGFNAEIITTSLDCEAREAGRFIASIMKEVKFKDRPL.....KKPAALIFGG
   2 GVSLEAAASRARAAGIEAVILSDAIEGEARDVGLVHAAIARETALRGRPF.....PKPALLLSGG
   3 QKVCDEAKSLAKEKGFNAEIITTSLDCEAREAGRFIASIMKEVKFKDRPL.....KKPAALIFGG
   4 ALACEAVERKAKELGLNAYILTTTLEGEAREVGIALGSIIEEVYHRNRPF.....KRPCVLIAGG
   5 QIALEAAARVARAAGYTPHILGDSLEGEARDLGLVMAGMARQVARRGQPF.....AAPCVLLSGG
   6 AVSLEAAAREASRHGVEAVILSDSVEGEAREVAHVHAAIAREVAERDRPF.....KKPVVILSGG
   7 GVSLEAAAAEARRQGIEAVILSDAIEGEAREVGGVHAAIAREVATRNRPF.....SKPVLILSGG
   8 RASLEAAAVLARSQAVSAVVLSDAIEGEASEVAKVHAVIAKEVARNDQPF.....RKPVVILSGG
   9 SVSLEAAAARARESGIEAMILSDAIEGEARDIGRMHAALAREVASRNRPF.....SKPVVLLSGG
  10 QNALDAAAVKCRAAGFSTLILGD-LEGEAREVAKVHAGIARQIRKHGQPL.....AAPCVILSGG
  11 SISCEAIAREAQRLGFKAYIMTTTLEGEAKDAGLFIGSIVQEIAERGRPF.....EPPVVLVFGG
  12 SLALAEAQRQAEVLGYHAMVLSTAMQGDVKRVARFYGLLARVAAAHLTPSl36kaKGPVCLLAGG
  13 LLSLRRASEYLSALGYKAVILTSMLEGEAREAGRVLASVAKSAAYSGLPE.....RPPLALLAGG
  14 SLALAEAQRQAEVLGYHAMVLSTAMQGDVKRVARFYGLLARVAAAHLTPSl36kaKGPVCLLAGG
  15 SLALAEAQRQAEVLGYHAMVLSTAMQGDVKRVARFYGLLARVAAAHLTPSl36kaKGPVCLLAGG
  16 SISCQAVVEEATKLGFKAYVMTTTLEGEAKDAGLFIGSIVQEIAKTGNPF.....EPPVVLVFGG
  17 SLALQAAAYEAVKLGLTPLILGDSLEGESRDVGAVMAGIASSASRKGLPV.....KGPAVLLSGG
  18 SLALAEAQRQAEVLGYHAMVLSTAMQGDVKRVARFYGLLARVAAAHLTPSl36kaKGPVCLLAGG
  19 VLALAEAQRQAEALGYQAVVLSAAMQGDVKSMAQFYGLLAHVARTRLTPSm36wgRGPVCLLAGG
  20 SLALQAAAYEAVKLGLTPLILGDSLEGESRDVGAVMAGIASSASRKGLPV.....KGPAVLLSGG
  21 VLALAEAQRQAEALGYQAVVLSAAMQGDVKSMAQFYGLLAHVARTRLTPSt36rgRGPVCLLAGG
  22 RLSLEAAAARADALGIPAIILSDAIEGEARDVGKVHAAIAREVVLRNRPF.....ERPVVLLSGG
  23 SMALDAAAAVAAANGLTPVILGDALQGEARDVGTVFAGIAMSASTKGLPV.....RGPAVLLSGG
  24 MDVLEDLAAWLGGRGFNTLVLTSRLEGESREVGRALASIALEALDRGVPV.....KPPAALLAGG
  25 SIALEAAAAAALDAGLCPLILGDALEGEAREMGRVMAGIALSARDKGLPV.....AAPAVILSGG
  26 IDALEAAAEAARRAGYEPVMLGSDLEGEAREVAAEHARLALEARQAG---.....-RRVALISGG
  27 NFALRAAAEYLTSSGYNSTIVTSSLSGNAAEIGKKFAEIITEKSITSSHLlk9ieNYPIALLFGG
  28 NFALRAAAEYLTSSGYNSTIVTSSLSGNAAEIGKKFAEIITEKSITSSHLlk9ieNYPIALLFGG
  29 QQSLVAGAQVFAAHGIHTAILGDTVTGEAREVAQVYGALARQVRRHGTPF.....AAPVALVSGG
  30 MEVLRKLANTL----VNSFILTSEIRGEARDVGAIIASIYNSSESYNIPF.....RRPYYLLVGG
  31 EVAVNCIVQQAQARGIECIVLSRTIEGNVIDLAPVYVALAAILYNLKTNFi36nkEKPLLIVGAG
  32 VIATSTAAHEAERLGYIPCVLSCAVQGDVAQVAGDYQRLLHGIQEAKQHGi30ssKKPLFLICGG
  33 RDFVDYIYSELDGEKIN---LGSNINGDVKVVSRDITDILKNILEIK---.....GEPFWFVCGG
  34 RDFVFEIYKRIN---EPIVSFGSNIQGDVTEVSEAFVRSIYEISKIK---.....GKSFWFVAGG
  35 RDFVRRIESYV---GEPIVSIGSGISGDVEDVSDGIIDIVRSVSRIK---.....GRSFWIVMGG
  36 RDFVRRIESYV---GEPIVSIGSGISGDVEDVSDGIIDIVRSVSRIK---.....GRSFWIVMGG
  37 NIVLRKLRDIV----QNPIILSSEIRGDAYSFGQNLAGIVN-TSFSNLGL.....KPPYTLLAGG
  38 RLLLEAAQKFLEGQGVRAVILGDTFEGEARELARLHASLVRSVQQYGSPL.....PPPLVLLSGG
  39 VLALAEAQRQAEALGYQAVVLSAAMQG-----------------------.....----------


            120          130       140           150
             |            |         |             |
   1 ETVVHVKGN...GIGGRNQELALSAAIALEGIE....GVILCSAGT
   2 ETTVTVRGE...GRGGRNSEFLLSLALGIDGIG....GISALAADT
   3 ETVVHVKGN...GIGGRNQELALSAAIALEGIE....GVILCSAGT
   4 ETTVTIQGEa..GLGGPNQELALSIARKIAGLR....GVAVLVIDT
   5 ETTVTLRGN...GRGGRNVEFLLSLAVALDGLP....GVHAIAGDT
   6 ETTVTIGSPg..GKGGRNSEFLLSFALDIDGYA....NIHALAADT
   7 ETTVTLRAK...GKGGRNSEFLLAFAIGISGVQ....GIHALAADT
   8 ETTVTLRGK...GKGGRNTEFLLSLAIEIAEHG....DITALAADT
   9 ETTVTISGEry.GKGGRNSEFLLSLALDIDGIG....GIDALAADT
  10 ETTVTVRGN...GRGGRNAEFLLSLTAELKGEP....NIWALAGDT
  11 ETTVTIEGKg..GKGGPNQEIALSATRKISDLE....-ALIVAFDT
  12 EPTVQLQGS...GKGGRNQELALHVGVELGRQPlgpiDVLFLSGGT
  13 ETVVTVRGG...GRGGRNQELCLSFSIAVRGLR....NISAACLGT
  14 EPTVQLQGS...GKGGRNQELALHVGVELGRQPlgpiDVLFLSGGT
  15 EPTVQLQGS...GKGGRNQELALHVGVELGRQPlgpiDVLFLSGGT
  16 ETTVTIEGEg..GKGGPNQELALSATRKIKGLN....-AILVAFDT
  17 ETTVTIGKGpa.GKGGRNTEFLLSLALTLKGAD....GIWAIAGDS
  18 EPTVQLQGS...GKGGRNQELALHVGVELGRQPlgpiDVLFLSGGT
  19 EPTVQLQGS...GRGGRNQELALRVGAELRRWPlgpiDVLFLSGGT
  20 ETTVTIGKGpa.GKGGRNTEFLLSLALTLKGAD....GIWAIAGDS
  21 EPTVQLQGS...GRGGRNQELALRVGAELRRWPlgqiDVLFLSGGT
  22 ETTVTLRGH...GRGGRNTEFLLSLAIAAEGL-....SFASLAADT
  23 ETSVSLPADtk.GRGGRNSEFLLSLAIGLDGAK....GIWALSGDT
  24 ETTVTVRGG...GRGGRNMELALAWSLAMAYWSpea.PAAILAMDT
  25 ESTVSLGAMte.GRGGRNTEFLLSLAVALKGAS....GIWAIAGDT
  26 ELTVTIRGE...GDGGPNQEYALALAIALDGAE....GIAGIAADT
  27 ETTVHLSENp..GKGGRNQEMVLSCLDALKTRVpah.NFTFLSAGT
  28 ETTVHLSENp..GKGGRNQEMVLSCLDALKTRVpah.NFTFLSAGT
  29 ECTVTLPPGltgGRGGRCAEFLLSLGIALEDMG....DVYALAADT
  30 EPEVTIQGKa..GKGGRNGEVCLSFLKYAKKRN....RFELLGFAT
  31 EPTVCVSGG...GKGGRNQELALRFTVGVRELErvpdSVYFLSAGT
  32 EPVIKVSGH...GLGGRSQHLALLMSQALHRDEamr.DCTFLSAGT
  33 ETTVTVTGN...GSGGRNQELAVRIMEDISN-N....DFLFISMGT
  34 ETTVNVKGN...GIGGRNLELALRFMK-LANFS....DFLFLSIGT
  35 ETTVNVRGN...GIGGRNLELSLLFMKKC-NFS....DFLFISMGT
  36 ETTVNVRGN...GIGGRNLELSLLFMKKC-NFS....DFLFISMGT
  37 EPDVKIEGKa..GKGGRNGEVCLGFLKWVKRNS....NH-------
  38 EATVS----...---------------------....---------
  39 ---------...---------------------....---------