PFRMAT SS TARGET T0187 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0187.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0187.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0187.t2k.str.rdb (weight 1.53983) METHOD T0187.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0187.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.str.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ MODEL 1 G C 0.91 P C 0.85 A C 0.70 W C 0.78 P C 0.85 D C 0.86 S C 0.69 S C 0.70 T C 0.70 S H 0.78 E H 0.83 D H 0.87 A H 0.95 L H 0.96 K H 0.96 V H 0.96 L H 0.96 E H 0.94 K H 0.87 Y H 0.52 G C 0.88 I C 0.87 E C 0.81 T C 0.87 S C 0.87 E H 0.73 S H 0.78 V H 0.82 K H 0.79 R H 0.73 A H 0.66 I H 0.53 L C 0.56 Q C 0.75 E C 0.82 T C 0.85 P C 0.78 K C 0.66 H C 0.64 L C 0.62 S C 0.66 N C 0.67 V E 0.50 E E 0.65 I E 0.86 H E 0.91 L E 0.92 I E 0.88 G E 0.61 N C 0.77 V C 0.55 Q H 0.83 K H 0.91 V H 0.93 C H 0.95 D H 0.96 E H 0.96 A H 0.96 K H 0.96 S H 0.95 L H 0.95 A H 0.95 K H 0.94 E H 0.88 K C 0.57 G C 0.94 F C 0.90 N C 0.69 A E 0.85 E E 0.91 I E 0.92 I E 0.85 T E 0.48 T C 0.64 S C 0.57 L C 0.51 D H 0.46 C H 0.53 E H 0.71 A H 0.91 R H 0.92 E H 0.93 A H 0.93 G H 0.95 R H 0.96 F H 0.95 I H 0.96 A H 0.96 S H 0.96 I H 0.96 M H 0.95 K H 0.95 E H 0.95 V H 0.94 K H 0.91 F H 0.82 K C 0.56 D C 0.92 R C 0.90 P C 0.84 L C 0.84 K C 0.89 K C 0.88 P C 0.68 A E 0.85 A E 0.92 L E 0.93 I E 0.87 F E 0.65 G C 0.77 G C 0.85 E C 0.65 T E 0.57 V E 0.75 V E 0.87 H E 0.89 V E 0.79 K E 0.56 G C 0.69 N C 0.83 G C 0.84 I C 0.85 G C 0.87 G C 0.79 R C 0.50 N H 0.71 Q H 0.92 E H 0.94 L H 0.95 A H 0.96 L H 0.96 S H 0.95 A H 0.95 A H 0.95 I H 0.94 A H 0.90 L H 0.84 E H 0.55 G C 0.77 I C 0.86 E C 0.86 G C 0.88 V E 0.49 I E 0.80 L E 0.89 C E 0.84 S E 0.69 A C 0.62 G C 0.83 T C 0.92 END