PFRMAT SS TARGET T0187 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0187.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0187.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0187.t2k.str.rdb (weight 1.53983) METHOD T0187.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0187.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.str.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0187.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0187 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0187.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ MODEL 1 M C 0.91 F C 0.83 D C 0.84 P C 0.65 E H 0.58 S H 0.62 L H 0.83 K H 0.88 K H 0.92 L H 0.93 A H 0.94 I H 0.95 E H 0.95 I H 0.95 V H 0.96 K H 0.96 K H 0.95 S H 0.94 I H 0.91 E H 0.84 A H 0.66 V C 0.64 F C 0.86 P H 0.70 D H 0.86 R H 0.91 A H 0.91 V H 0.88 K H 0.82 E H 0.64 T C 0.49 L C 0.78 P C 0.80 K C 0.75 L C 0.82 N C 0.80 L C 0.87 D C 0.86 R C 0.65 V E 0.76 I E 0.92 L E 0.93 V E 0.89 A E 0.82 V C 0.51 G C 0.68 K H 0.69 A H 0.81 A H 0.89 W H 0.94 R H 0.94 M H 0.95 A H 0.95 K H 0.96 A H 0.95 A H 0.96 Y H 0.95 E H 0.93 V H 0.86 L H 0.69 G C 0.50 K C 0.63 K C 0.60 I C 0.62 R C 0.69 K C 0.73 G E 0.57 V E 0.88 V E 0.91 V E 0.89 T E 0.73 K C 0.61 Y C 0.85 G C 0.87 H C 0.80 S C 0.78 E C 0.77 G C 0.79 P C 0.76 I C 0.80 D C 0.80 D C 0.59 F E 0.67 E E 0.85 I E 0.90 Y E 0.85 E E 0.76 A C 0.52 G C 0.77 H C 0.87 P C 0.82 V C 0.83 P C 0.87 D C 0.83 E H 0.76 N H 0.81 T H 0.92 I H 0.96 K H 0.96 T H 0.96 T H 0.96 R H 0.96 R H 0.96 V H 0.96 L H 0.95 E H 0.95 L H 0.91 V H 0.86 D H 0.67 Q C 0.71 L C 0.88 N C 0.93 E C 0.72 N C 0.82 D C 0.71 T E 0.79 V E 0.92 L E 0.93 F E 0.93 L E 0.89 L E 0.71 S C 0.57 G C 0.80 G C 0.73 G C 0.51 S H 0.49 S H 0.48 L C 0.48 F C 0.61 E C 0.59 L C 0.69 P C 0.76 L C 0.68 E C 0.81 G C 0.87 V C 0.79 S C 0.87 L H 0.90 E H 0.94 E H 0.95 I H 0.95 Q H 0.95 K H 0.94 L H 0.93 T H 0.92 S H 0.91 A H 0.88 L H 0.79 L H 0.53 K C 0.86 END