PFRMAT SS TARGET T0185 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0185.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0185.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0185.t2k.str.rdb (weight 1.53983) METHOD T0185.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0185.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0185 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0185.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 248 METHOD METHOD ============================================ METHOD Comments from T0185.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0185 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0185.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 248 METHOD METHOD ============================================ METHOD Comments from T0185.t2k.str.rdb METHOD ============================================ METHOD TARGET T0185 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0185.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 248 METHOD METHOD ============================================ METHOD Comments from T0185.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0185 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0185.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 248 METHOD METHOD ============================================ MODEL 1 M C 0.66 E C 0.69 R C 0.84 V C 0.81 P C 0.55 I E 0.43 E E 0.43 N C 0.40 R H 0.66 L H 0.85 H H 0.89 Y H 0.89 F H 0.86 R H 0.81 D H 0.75 T H 0.68 L H 0.52 K C 0.55 R C 0.67 E C 0.76 K C 0.87 K C 0.82 E C 0.50 E E 0.90 F E 0.92 A E 0.92 V E 0.89 T E 0.72 G C 0.73 T C 0.87 D C 0.89 G C 0.89 K C 0.51 T H 0.76 T H 0.88 T H 0.94 T H 0.96 A H 0.96 M H 0.96 V H 0.96 A H 0.96 H H 0.96 V H 0.96 L H 0.95 K H 0.92 H H 0.84 L C 0.54 R C 0.92 K C 0.89 S C 0.83 P C 0.63 T C 0.49 V C 0.40 F C 0.42 L C 0.58 G C 0.71 G C 0.66 I C 0.54 M C 0.53 D C 0.50 S C 0.40 L H 0.48 E H 0.48 H H 0.53 G H 0.55 N H 0.44 Y C 0.50 E C 0.64 K C 0.79 G C 0.86 N C 0.78 G C 0.61 P E 0.88 V E 0.92 V E 0.93 Y E 0.90 E E 0.88 L E 0.70 D C 0.66 E C 0.74 S C 0.81 E C 0.79 E C 0.73 F C 0.56 F C 0.51 S C 0.47 E C 0.46 F C 0.54 S C 0.68 P C 0.68 N C 0.59 Y E 0.91 L E 0.93 I E 0.93 I E 0.90 T E 0.72 N C 0.58 A C 0.76 R C 0.85 G H 0.65 D H 0.71 H H 0.74 L H 0.73 E H 0.63 N H 0.52 Y C 0.70 G C 0.83 N C 0.86 S C 0.75 L H 0.94 T H 0.95 R H 0.95 Y H 0.96 R H 0.96 S H 0.95 A H 0.94 F H 0.95 E H 0.94 K H 0.93 I H 0.91 S H 0.87 R H 0.75 N C 0.52 T C 0.79 D C 0.84 L E 0.65 V E 0.87 V E 0.89 T E 0.81 F C 0.58 A C 0.84 E C 0.89 D C 0.82 E H 0.62 L H 0.61 T H 0.64 S H 0.50 H C 0.56 L C 0.71 G C 0.70 D E 0.65 V E 0.78 T E 0.81 F E 0.72 G E 0.52 V C 0.63 K C 0.79 K C 0.78 G C 0.75 T C 0.59 Y C 0.44 T E 0.57 L E 0.63 E E 0.60 M E 0.63 R E 0.67 S E 0.69 A E 0.66 S E 0.49 R C 0.57 A C 0.71 E C 0.70 Q C 0.52 K E 0.71 A E 0.84 M E 0.89 V E 0.90 E E 0.87 K E 0.71 N C 0.73 G C 0.80 K C 0.50 R E 0.66 Y E 0.70 L E 0.66 E E 0.74 L E 0.78 K E 0.73 L E 0.58 K C 0.59 V C 0.68 P C 0.73 G C 0.67 F H 0.73 H H 0.77 N H 0.87 V H 0.95 L H 0.95 N H 0.96 A H 0.96 L H 0.96 A H 0.96 V H 0.96 I H 0.96 A H 0.96 L H 0.96 F H 0.96 D H 0.95 S H 0.89 L C 0.54 G C 0.93 Y C 0.93 D C 0.92 L H 0.92 A H 0.95 P H 0.95 V H 0.96 L H 0.95 E H 0.94 A H 0.92 L H 0.90 E H 0.83 E H 0.63 F C 0.64 R C 0.74 G C 0.77 V C 0.80 H C 0.81 R C 0.88 R C 0.93 END