PFRMAT SS TARGET T0180 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0180.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0180.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0180.t2k.str.rdb (weight 1.53983) METHOD T0180.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0180.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0180 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0180.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from T0180.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0180 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0180.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from T0180.t2k.str.rdb METHOD ============================================ METHOD TARGET T0180 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0180.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from T0180.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0180 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0180.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ MODEL 1 M C 0.89 V C 0.74 G C 0.75 R C 0.71 R C 0.78 P C 0.79 G C 0.84 G C 0.84 G C 0.76 L C 0.64 K C 0.66 D C 0.70 T C 0.74 K C 0.72 P C 0.57 V E 0.75 V E 0.85 V E 0.84 R E 0.82 L E 0.65 Y C 0.67 P C 0.57 D H 0.49 E H 0.66 I H 0.70 E H 0.69 A H 0.68 L H 0.64 K H 0.61 S H 0.48 R C 0.56 V C 0.72 P C 0.77 A C 0.65 N C 0.65 T C 0.55 S H 0.47 M H 0.72 S H 0.80 A H 0.85 Y H 0.87 I H 0.88 R H 0.90 R H 0.88 I H 0.88 I H 0.84 L H 0.80 N H 0.67 H H 0.55 L C 0.48 E C 0.60 D C 0.76 D C 0.92 END