PFRMAT SS TARGET T0179 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0179.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0179.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0179.t2k.str.rdb (weight 1.53983) METHOD T0179.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0179.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0179 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0179.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 135 METHOD METHOD ============================================ METHOD Comments from T0179.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0179 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0179.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 135 METHOD METHOD ============================================ METHOD Comments from T0179.t2k.str.rdb METHOD ============================================ METHOD TARGET T0179 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0179.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 135 METHOD METHOD ============================================ METHOD Comments from T0179.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0179 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0179.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 135 METHOD METHOD ============================================ MODEL 1 M C 0.89 S C 0.81 E C 0.69 L C 0.57 W E 0.48 Y E 0.61 T E 0.63 E E 0.57 K E 0.45 Q C 0.57 T C 0.79 K C 0.86 N C 0.88 F C 0.62 G E 0.68 I E 0.83 T E 0.89 M E 0.88 K E 0.87 V E 0.73 N E 0.60 K E 0.57 T E 0.55 L E 0.56 H E 0.44 T C 0.45 E C 0.62 Q C 0.75 T C 0.85 E C 0.78 F C 0.71 Q C 0.52 H E 0.72 L E 0.88 E E 0.92 M E 0.92 V E 0.89 E E 0.85 T E 0.58 E C 0.76 E C 0.78 F C 0.74 G C 0.78 N E 0.51 M E 0.87 L E 0.92 F E 0.91 L E 0.85 D C 0.57 G C 0.72 M E 0.62 V E 0.78 M E 0.76 T E 0.75 S C 0.47 E C 0.66 K C 0.67 D C 0.62 E H 0.55 F H 0.70 V H 0.76 Y H 0.83 H H 0.87 E H 0.88 M H 0.88 V H 0.85 A H 0.77 H H 0.64 V H 0.66 P H 0.66 L H 0.66 F H 0.52 T C 0.60 H C 0.81 P C 0.85 N C 0.87 P C 0.85 E C 0.80 H E 0.65 V E 0.92 L E 0.93 V E 0.92 V E 0.82 G C 0.53 G C 0.82 G C 0.82 D C 0.67 G H 0.60 G H 0.89 V H 0.93 I H 0.95 R H 0.95 E H 0.95 I H 0.93 L H 0.87 K H 0.66 H C 0.65 P C 0.84 S C 0.82 V C 0.63 K C 0.50 K E 0.77 A E 0.85 T E 0.83 L E 0.87 V E 0.85 D E 0.71 I C 0.73 D C 0.89 G H 0.90 K H 0.94 V H 0.95 I H 0.96 E H 0.96 Y H 0.95 S H 0.95 K H 0.93 K H 0.87 F H 0.77 L C 0.54 P C 0.58 S C 0.52 I C 0.58 A C 0.66 G C 0.66 K C 0.65 L C 0.69 D C 0.75 D C 0.82 P C 0.76 R C 0.59 V E 0.64 D E 0.81 V E 0.89 Q E 0.87 V E 0.74 D C 0.52 D C 0.61 G H 0.79 F H 0.88 M H 0.88 H H 0.86 I H 0.78 A H 0.72 K H 0.56 S C 0.63 E C 0.75 N C 0.81 Q C 0.79 Y C 0.67 D E 0.53 V E 0.92 I E 0.93 M E 0.93 V E 0.85 D C 0.59 S C 0.83 T C 0.85 E C 0.86 P C 0.83 V C 0.80 G C 0.83 P C 0.77 A C 0.52 V H 0.66 N H 0.69 L H 0.63 F H 0.50 T H 0.59 K H 0.93 G H 0.95 F H 0.95 Y H 0.96 A H 0.96 G H 0.95 I H 0.95 A H 0.94 K H 0.88 A H 0.67 L C 0.55 K C 0.83 E C 0.78 D C 0.79 G E 0.53 I E 0.83 F E 0.91 V E 0.90 A E 0.87 Q E 0.69 T C 0.65 D C 0.87 N C 0.85 P C 0.72 W C 0.69 F C 0.70 T C 0.62 P H 0.89 E H 0.93 L H 0.94 I H 0.95 T H 0.96 N H 0.95 V H 0.95 Q H 0.95 R H 0.94 D H 0.92 V H 0.91 K H 0.87 E H 0.76 I H 0.61 F C 0.74 P C 0.75 I C 0.46 T E 0.67 K E 0.77 L E 0.75 Y E 0.66 T E 0.65 A E 0.64 N E 0.69 I E 0.62 P C 0.50 T C 0.57 Y C 0.72 P C 0.80 S C 0.84 G C 0.79 L E 0.48 W E 0.79 T E 0.87 F E 0.89 T E 0.89 I E 0.86 G E 0.71 S C 0.52 K C 0.73 K C 0.79 Y C 0.82 D C 0.83 P C 0.52 L H 0.50 A H 0.50 V C 0.54 E C 0.66 D C 0.60 S C 0.59 R C 0.61 F C 0.53 F C 0.56 D C 0.57 I C 0.63 E C 0.67 T C 0.57 K C 0.46 Y C 0.48 Y C 0.64 T C 0.80 K H 0.60 D H 0.58 I H 0.67 H H 0.66 K H 0.65 A H 0.60 A H 0.60 F H 0.48 V C 0.46 L C 0.79 P H 0.58 K H 0.88 F H 0.91 V H 0.92 S H 0.91 D H 0.85 L H 0.75 I H 0.53 K C 0.84 END