PFRMAT SS TARGET T0178 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0178.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0178.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0178.t2k.str.rdb (weight 1.53983) METHOD T0178.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0178.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0178 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0178.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 52 METHOD METHOD ============================================ METHOD Comments from T0178.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0178 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0178.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 52 METHOD METHOD ============================================ METHOD Comments from T0178.t2k.str.rdb METHOD ============================================ METHOD TARGET T0178 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0178.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 52 METHOD METHOD ============================================ METHOD Comments from T0178.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0178 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0178.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 52 METHOD METHOD ============================================ MODEL 1 M C 0.74 I H 0.65 D H 0.70 V H 0.84 R H 0.87 K H 0.87 Y H 0.85 I H 0.79 D H 0.73 N H 0.69 A H 0.51 A C 0.67 L C 0.80 K C 0.88 P C 0.77 H C 0.85 L C 0.87 S C 0.91 E H 0.92 K H 0.95 E H 0.95 I H 0.96 E H 0.96 E H 0.96 F H 0.96 V H 0.96 L H 0.95 K H 0.94 S H 0.93 E H 0.88 E H 0.73 L C 0.65 G C 0.92 I C 0.82 Y E 0.60 A E 0.88 V E 0.91 C E 0.89 V E 0.68 N C 0.78 P C 0.56 Y H 0.59 H H 0.70 V H 0.85 K H 0.94 L H 0.94 A H 0.95 S H 0.94 S H 0.91 I H 0.80 A H 0.56 K C 0.62 K C 0.85 V C 0.75 K E 0.56 V E 0.89 C E 0.87 C E 0.83 V E 0.77 I C 0.49 G C 0.74 F C 0.80 P C 0.80 L C 0.83 G C 0.87 L C 0.82 N C 0.76 K C 0.46 T H 0.78 S H 0.89 V H 0.91 K H 0.94 V H 0.95 K H 0.96 E H 0.96 A H 0.95 V H 0.96 E H 0.95 A H 0.94 V H 0.92 R H 0.83 D C 0.63 G C 0.85 A C 0.84 Q C 0.69 E E 0.55 L E 0.68 D E 0.72 I E 0.83 V E 0.74 W E 0.60 N C 0.61 L H 0.68 S H 0.78 A H 0.83 F H 0.81 K H 0.67 S C 0.58 E C 0.85 K C 0.71 Y H 0.88 D H 0.93 F H 0.94 V H 0.95 V H 0.96 E H 0.96 E H 0.96 L H 0.96 K H 0.96 E H 0.96 I H 0.96 F H 0.95 R H 0.93 E H 0.85 T H 0.49 P C 0.80 S C 0.89 A C 0.74 V E 0.62 H E 0.86 K E 0.89 V E 0.90 I E 0.87 V E 0.78 E E 0.60 T C 0.50 P C 0.58 Y C 0.61 L C 0.80 N C 0.90 E H 0.92 E H 0.95 E H 0.95 I H 0.96 K H 0.96 K H 0.96 A H 0.96 V H 0.96 E H 0.96 I H 0.96 C H 0.96 I H 0.95 E H 0.92 A H 0.51 G C 0.90 A C 0.89 D C 0.77 F E 0.63 I E 0.70 K E 0.67 T C 0.55 S C 0.75 T C 0.81 G C 0.85 F C 0.80 A C 0.79 P C 0.82 R C 0.86 G C 0.90 T C 0.88 T C 0.84 L H 0.94 E H 0.95 E H 0.96 V H 0.96 R H 0.96 L H 0.96 I H 0.96 K H 0.96 S H 0.95 S H 0.90 A H 0.71 K H 0.49 G C 0.60 R C 0.70 I C 0.74 K C 0.72 V E 0.55 K E 0.61 A C 0.47 S C 0.69 G C 0.81 G C 0.78 I C 0.68 R C 0.74 D C 0.86 L H 0.93 E H 0.95 T H 0.95 A H 0.96 I H 0.96 S H 0.96 M H 0.96 I H 0.95 E H 0.94 A H 0.88 G H 0.82 A H 0.81 D H 0.82 R H 0.77 I H 0.61 G C 0.53 T H 0.47 S H 0.59 S H 0.74 G H 0.86 I H 0.93 S H 0.94 I H 0.94 A H 0.91 E H 0.81 E H 0.60 F C 0.53 L C 0.64 K C 0.74 R C 0.75 H C 0.73 L C 0.80 I C 0.92 END