PFRMAT SS TARGET T0176 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0176.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0176.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0176.t2k.str.rdb (weight 1.53983) METHOD T0176.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0176.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0176 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0176.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 31 METHOD METHOD ============================================ METHOD Comments from T0176.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0176 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0176.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 31 METHOD METHOD ============================================ METHOD Comments from T0176.t2k.str.rdb METHOD ============================================ METHOD TARGET T0176 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0176.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 31 METHOD METHOD ============================================ METHOD Comments from T0176.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0176 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0176.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 31 METHOD METHOD ============================================ MODEL 1 M C 0.87 D C 0.77 G C 0.71 V C 0.51 M H 0.47 S H 0.52 A H 0.48 V E 0.38 T E 0.55 V E 0.59 N C 0.48 D C 0.84 D C 0.91 G C 0.60 L E 0.83 V E 0.91 L E 0.93 R E 0.93 L E 0.92 Y E 0.91 I E 0.83 Q C 0.54 P C 0.79 K C 0.87 A C 0.75 S C 0.71 R C 0.60 D C 0.66 S C 0.62 I C 0.48 V C 0.49 G C 0.58 L C 0.69 H C 0.77 G C 0.79 D C 0.76 E E 0.61 V E 0.85 K E 0.90 V E 0.92 A E 0.90 I E 0.81 T E 0.55 A C 0.78 P C 0.90 P C 0.87 V C 0.77 D C 0.61 G H 0.49 Q H 0.80 A H 0.87 N H 0.92 S H 0.95 H H 0.96 L H 0.96 V H 0.96 K H 0.96 F H 0.96 L H 0.96 G H 0.96 K H 0.94 Q H 0.86 F H 0.48 R C 0.92 V C 0.90 A C 0.88 K C 0.50 S C 0.49 Q C 0.37 V E 0.73 V E 0.87 I E 0.86 E E 0.71 K C 0.60 G C 0.77 E C 0.71 L C 0.67 G C 0.70 R C 0.69 H C 0.61 K E 0.55 Q E 0.75 I E 0.85 K E 0.85 I E 0.67 I C 0.71 N C 0.89 P C 0.83 Q C 0.74 Q C 0.67 I C 0.75 P H 0.74 P H 0.90 E H 0.92 V H 0.92 A H 0.90 A H 0.85 L H 0.73 I C 0.53 N C 0.92 END