PFRMAT SS TARGET T0175 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0175.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0175.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0175.t2k.str.rdb (weight 1.53983) METHOD T0175.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0175.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0175 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0175.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 561 METHOD METHOD ============================================ METHOD Comments from T0175.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0175 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0175.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 561 METHOD METHOD ============================================ METHOD Comments from T0175.t2k.str.rdb METHOD ============================================ METHOD TARGET T0175 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0175.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 561 METHOD METHOD ============================================ METHOD Comments from T0175.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0175 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0175.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 561 METHOD METHOD ============================================ MODEL 1 M C 0.88 D C 0.77 I C 0.67 P C 0.59 R C 0.55 I C 0.56 F C 0.54 T C 0.52 I C 0.54 S C 0.53 E C 0.56 S C 0.61 E C 0.60 H C 0.64 R C 0.63 I C 0.64 H C 0.60 N C 0.54 P H 0.68 F H 0.67 T H 0.76 E H 0.90 E H 0.91 K H 0.93 Y H 0.95 A H 0.95 T H 0.95 L H 0.95 G H 0.95 R H 0.92 V H 0.85 L H 0.50 R C 0.86 M C 0.90 K C 0.92 P C 0.86 G C 0.90 T C 0.70 R E 0.79 I E 0.88 L E 0.88 D E 0.85 L E 0.52 G C 0.68 S C 0.79 G C 0.77 S C 0.59 G H 0.60 E H 0.94 M H 0.95 L H 0.96 C H 0.96 T H 0.96 W H 0.96 A H 0.95 R H 0.91 D H 0.80 H C 0.58 G C 0.93 I C 0.83 T E 0.65 G E 0.89 T E 0.88 G E 0.90 I E 0.84 D E 0.52 M C 0.86 S C 0.91 S H 0.91 L H 0.94 F H 0.95 T H 0.96 A H 0.96 Q H 0.96 A H 0.95 K H 0.96 R H 0.95 R H 0.95 A H 0.95 E H 0.94 E H 0.89 L C 0.50 G C 0.91 V C 0.86 S C 0.77 E C 0.73 R C 0.73 V E 0.63 H E 0.87 F E 0.90 I E 0.87 H E 0.78 N C 0.53 D C 0.69 A H 0.52 A H 0.53 G H 0.48 Y C 0.78 V C 0.79 A C 0.76 N C 0.70 E C 0.76 K C 0.82 C C 0.82 D C 0.72 V E 0.91 A E 0.93 A E 0.92 C E 0.85 V C 0.56 G C 0.52 A H 0.53 T H 0.67 W H 0.62 I C 0.53 A C 0.81 G C 0.81 G C 0.82 F H 0.83 A H 0.92 G H 0.95 A H 0.95 E H 0.96 E H 0.96 L H 0.95 L H 0.95 A H 0.94 Q H 0.87 S H 0.63 L C 0.62 K C 0.83 P C 0.69 G C 0.73 G E 0.54 I E 0.86 M E 0.93 L E 0.92 I E 0.90 G E 0.78 E E 0.55 P C 0.65 Y C 0.74 W C 0.72 R C 0.71 Q C 0.69 L C 0.68 P C 0.65 A C 0.58 T C 0.54 E C 0.47 E H 0.49 I H 0.52 A H 0.55 Q H 0.56 A H 0.56 C H 0.53 G C 0.45 V C 0.55 S C 0.66 S C 0.70 T C 0.70 S C 0.70 D C 0.71 F C 0.79 L C 0.83 T C 0.87 L H 0.90 P H 0.94 G H 0.95 L H 0.96 V H 0.96 G H 0.96 A H 0.96 F H 0.95 D H 0.93 D H 0.83 L C 0.63 G C 0.94 Y C 0.84 D E 0.59 V E 0.80 V E 0.83 E E 0.81 M E 0.77 V E 0.67 L E 0.54 A C 0.58 D C 0.66 Q C 0.60 E C 0.63 G C 0.63 W H 0.48 D H 0.56 R H 0.55 Y H 0.54 E H 0.58 A H 0.70 A H 0.75 K H 0.80 W H 0.85 L H 0.85 T H 0.87 M H 0.92 R H 0.94 R H 0.94 W H 0.93 L H 0.92 E H 0.85 A H 0.70 N H 0.56 P H 0.63 D H 0.67 D H 0.68 D H 0.80 F H 0.84 A H 0.89 A H 0.91 E H 0.90 V H 0.90 R H 0.89 A H 0.87 E H 0.85 L H 0.78 N H 0.70 I H 0.61 A C 0.49 P H 0.62 K H 0.80 R H 0.85 Y H 0.88 V H 0.92 T H 0.93 Y H 0.94 A H 0.95 R H 0.95 E H 0.95 C H 0.95 F H 0.94 G H 0.94 W H 0.94 G H 0.94 V H 0.93 F H 0.90 A H 0.85 L H 0.77 I H 0.58 A C 0.61 R C 0.91 END