PFRMAT SS TARGET T0171 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0171.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0171.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0171.t2k.str.rdb (weight 1.53983) METHOD T0171.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0171.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0171 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0171.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 704 METHOD METHOD ============================================ METHOD Comments from T0171.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0171 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0171.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 704 METHOD METHOD ============================================ METHOD Comments from T0171.t2k.str.rdb METHOD ============================================ METHOD TARGET T0171 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0171.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 704 METHOD METHOD ============================================ METHOD Comments from T0171.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0171 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0171.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 704 METHOD METHOD ============================================ MODEL 1 M C 0.90 N C 0.55 N E 0.81 I E 0.88 W E 0.90 W E 0.90 Q E 0.85 T E 0.76 K C 0.64 G C 0.85 Q C 0.86 G C 0.88 N C 0.87 V C 0.83 H E 0.65 L E 0.93 V E 0.93 L E 0.93 L E 0.88 H E 0.49 G C 0.81 W C 0.83 G C 0.79 L C 0.74 N C 0.75 A H 0.56 E H 0.65 V H 0.69 W H 0.83 R H 0.90 C H 0.90 I H 0.90 D H 0.91 E H 0.91 E H 0.86 L H 0.81 S H 0.67 S C 0.68 H C 0.89 F C 0.75 T E 0.62 L E 0.92 H E 0.92 L E 0.90 V E 0.79 D C 0.57 L C 0.82 P C 0.80 G C 0.79 F C 0.79 G C 0.79 R C 0.79 S C 0.79 R C 0.82 G C 0.84 F C 0.83 G C 0.82 A C 0.79 L C 0.80 S C 0.82 L H 0.92 A H 0.94 D H 0.95 M H 0.95 A H 0.94 E H 0.93 A H 0.91 V H 0.91 L H 0.87 Q H 0.71 Q C 0.64 A C 0.88 P C 0.89 D C 0.84 K E 0.53 A E 0.89 I E 0.93 W E 0.93 L E 0.89 G E 0.71 W C 0.63 S C 0.73 L H 0.75 G H 0.92 G H 0.95 L H 0.96 V H 0.96 A H 0.96 S H 0.96 Q H 0.96 I H 0.95 A H 0.94 L H 0.88 T H 0.71 H C 0.76 P H 0.54 E C 0.54 R H 0.55 V C 0.46 Q E 0.62 A E 0.84 L E 0.91 V E 0.92 T E 0.89 V E 0.77 A C 0.51 S C 0.72 S C 0.75 P C 0.76 C C 0.74 F C 0.71 S C 0.70 A C 0.68 R C 0.64 D C 0.58 E C 0.54 W C 0.50 P H 0.50 G H 0.54 I H 0.53 K H 0.62 P H 0.77 D H 0.78 V H 0.80 L H 0.79 A H 0.77 G H 0.74 F H 0.70 Q H 0.69 Q H 0.63 Q H 0.53 L C 0.50 S C 0.51 D H 0.51 D H 0.50 F H 0.73 Q H 0.82 R H 0.82 T H 0.83 V H 0.83 E H 0.82 R H 0.77 F H 0.73 L H 0.69 A H 0.62 L H 0.52 Q C 0.48 T C 0.54 M C 0.62 G C 0.61 T C 0.61 E C 0.68 T C 0.76 A C 0.75 R H 0.88 Q H 0.91 D H 0.92 A H 0.94 R H 0.93 A H 0.93 L H 0.91 K H 0.90 K H 0.85 T H 0.78 V H 0.64 L H 0.51 A C 0.58 L C 0.61 P C 0.62 M C 0.52 P H 0.49 E H 0.57 V H 0.81 D H 0.87 V H 0.88 L H 0.89 N H 0.88 G H 0.87 G H 0.85 L H 0.83 E H 0.79 I H 0.74 L H 0.63 K H 0.54 T C 0.52 V C 0.51 D C 0.51 L H 0.59 R H 0.71 Q H 0.71 P H 0.69 L H 0.65 Q H 0.52 N C 0.64 V C 0.79 S C 0.84 M C 0.82 P C 0.72 F E 0.88 L E 0.93 R E 0.93 L E 0.91 Y E 0.72 G C 0.72 Y C 0.81 L C 0.82 D C 0.82 G C 0.78 L C 0.73 V C 0.79 P C 0.84 R H 0.81 K H 0.88 V H 0.91 V H 0.93 P H 0.94 M H 0.94 L H 0.94 D H 0.93 K H 0.84 L H 0.66 W C 0.84 P C 0.86 H C 0.90 S C 0.71 E E 0.71 S E 0.90 Y E 0.91 I E 0.88 F E 0.60 A C 0.81 K C 0.90 A C 0.82 A C 0.80 H C 0.74 A C 0.72 P C 0.61 F C 0.49 I H 0.50 S C 0.55 H C 0.73 P H 0.87 A H 0.93 E H 0.95 F H 0.95 C H 0.96 H H 0.96 L H 0.96 L H 0.95 V H 0.95 A H 0.94 L H 0.93 K H 0.88 Q H 0.72 R C 0.51 V C 0.90 END