PFRMAT SS TARGET T0170 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0170.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0170.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0170.t2k.str.rdb (weight 1.53983) METHOD T0170.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0170.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0170 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0170.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0170.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0170 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0170.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0170.t2k.str.rdb METHOD ============================================ METHOD TARGET T0170 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0170.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ METHOD Comments from T0170.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0170 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0170.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 30 METHOD METHOD ============================================ MODEL 1 Q C 0.86 P C 0.60 A H 0.57 K H 0.70 K H 0.73 T H 0.72 Y H 0.69 T H 0.68 W H 0.60 N H 0.52 T H 0.60 K H 0.90 E H 0.93 E H 0.94 A H 0.93 K H 0.95 Q H 0.95 A H 0.94 F H 0.94 K H 0.95 E H 0.95 L H 0.94 L H 0.92 K H 0.87 E H 0.73 K C 0.58 R C 0.89 V C 0.86 P C 0.90 S C 0.85 N C 0.91 A C 0.83 S C 0.76 W H 0.88 E H 0.90 Q H 0.91 A H 0.90 M H 0.91 K H 0.92 M H 0.91 I H 0.86 I H 0.72 N C 0.52 D C 0.83 P C 0.60 R C 0.52 Y H 0.51 S H 0.51 A H 0.45 L C 0.51 A C 0.72 N C 0.82 L H 0.69 S H 0.83 E H 0.88 K H 0.92 K H 0.93 Q H 0.93 A H 0.94 F H 0.95 N H 0.95 A H 0.95 Y H 0.94 K H 0.92 V H 0.89 Q H 0.80 T H 0.62 E C 0.62 K C 0.91 END