PFRMAT SS TARGET T0169 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0169.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0169.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0169.t2k.str.rdb (weight 1.53983) METHOD T0169.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0169.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0169 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0169.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 246 METHOD METHOD ============================================ METHOD Comments from T0169.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0169 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0169.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 246 METHOD METHOD ============================================ METHOD Comments from T0169.t2k.str.rdb METHOD ============================================ METHOD TARGET T0169 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0169.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 246 METHOD METHOD ============================================ METHOD Comments from T0169.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0169 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0169.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 246 METHOD METHOD ============================================ MODEL 1 M C 0.87 D E 0.50 I E 0.62 R E 0.54 T C 0.55 I C 0.80 T C 0.89 S H 0.64 S H 0.64 D H 0.68 Y H 0.90 E H 0.92 M H 0.93 V H 0.95 T H 0.95 S H 0.94 V H 0.93 L H 0.91 N H 0.83 E H 0.71 W C 0.48 W C 0.75 G C 0.74 G C 0.69 R C 0.61 Q C 0.49 L H 0.52 K H 0.67 E H 0.83 K H 0.87 L H 0.89 P H 0.91 R H 0.92 L H 0.91 F H 0.90 F H 0.84 E H 0.66 H C 0.64 F C 0.80 Q C 0.82 D C 0.81 T C 0.52 S E 0.85 F E 0.92 I E 0.92 T E 0.91 S E 0.84 E E 0.59 H C 0.92 N C 0.92 S E 0.77 M E 0.91 T E 0.88 G E 0.92 F E 0.93 L E 0.93 I E 0.92 G E 0.88 F E 0.80 Q E 0.58 S C 0.70 Q C 0.77 S C 0.78 D C 0.74 P C 0.72 E C 0.60 T E 0.70 A E 0.84 Y E 0.88 I E 0.90 H E 0.84 F E 0.88 S E 0.87 G E 0.89 V E 0.77 H C 0.68 P H 0.61 D H 0.62 F H 0.72 R C 0.55 K C 0.71 M C 0.70 Q C 0.68 I H 0.65 G H 0.87 K H 0.95 Q H 0.96 L H 0.96 Y H 0.96 D H 0.96 V H 0.96 F H 0.96 I H 0.96 E H 0.96 T H 0.95 V H 0.95 K H 0.94 Q H 0.83 R C 0.72 G C 0.95 C C 0.88 T C 0.57 R E 0.89 V E 0.92 K E 0.92 C E 0.89 V E 0.81 T E 0.61 S C 0.72 P C 0.81 V C 0.82 N C 0.71 K H 0.83 V H 0.92 S H 0.95 I H 0.96 A H 0.96 Y H 0.96 H H 0.95 T H 0.93 K H 0.83 L C 0.57 G C 0.92 F C 0.77 D E 0.65 I E 0.77 E E 0.75 K E 0.73 G E 0.76 T E 0.77 K E 0.68 T C 0.51 V C 0.68 N C 0.78 G C 0.69 I C 0.49 S E 0.64 V E 0.71 F E 0.69 A E 0.64 N E 0.53 Y C 0.57 D C 0.80 G C 0.87 P C 0.83 G C 0.66 Q C 0.53 D C 0.41 R H 0.45 V E 0.47 L E 0.50 F E 0.48 V E 0.44 K C 0.43 N C 0.72 I C 0.92 END