(c) 1992-2000 Regents of the University of California, Santa Cruz
Sequence Alignment and Modeling Software System
http://www.cse.ucsc.edu/research/compbio/sam.html

Citations (SAM, SAM-T99, HMMs)

Sequence numbers correspond to the following labels:

    • T0162 F-actin capping protein alpha-1 subunit, chicken
    • gi|5453597|ref|NP_006126.1|_1:286 (NM_006135) F-actin capping protein alpha-1 subunit; Cap Z [Homo sapiens]
    • gi|16161888|ref|XP_052116.3| (XM_052116) F-actin capping protein alpha-1 subunit [Homo sapiens]
    • gi|1705650sp|P52907|CAZ1_HUMAN F-actin capping protein alpha-1 subunit (CapZ alpha-1)
    • gi|7448799|pir||G02639 capping protein alpha subunit isoform 1 - human
    • gi|1336099|gb|AAC00533.1| (U56637) capping protein alpha subunit isoform 1 [Homo sapiens]
    • gi|12652785|gb|AAH00144.1|AAH00144 (BC000144) capping protein (actin filament) muscle Z-line, alpha 1 [Homo sapiens]
    • gi|20875137|ref|XP_131135.1|_1:286 (XM_131135) capping protein alpha 1 [Mus musculus]
    • gi|16740716|gb|AAH16232.1|AAH16232_1:286 (BC016232) Similar to capping protein (actin filament) muscle Z-line, alpha 1 [Mus musculus]
    • gi|115579sp|P28497|CAZ2_CHICK_1:286 F-ACTIN CAPPING PROTEIN ALPHA-2 SUBUNIT (CAPZ 36/32) (BETA-ACTININ SUBUNIT I)
    • gi|486823|pir||S36093 actin-capping protein alpha-2 chain - chicken
    • gi|211423|gb|AAA48656.1| (M80589) capping protein alpha 2 isoform [Gallus gallus]
    • gi|115592sp|P13127|CAZ1_CHICK_1:286 F-ACTIN CAPPING PROTEIN ALPHA-1 SUBUNIT (CAPZ 36/32) (BETA-ACTININ SUBUNIT I)
    • gi|104524|pir||A33546 actin-capping protein alpha chain - chicken
    • gi|211425|gb|AAA48657.1| (M25534) put. actin-capping protein alpha subunit; putative [Gallus gallus]
    • gi|1345694sp|P47753|CAZ1_MOUSE_2:284 F-actin capping protein alpha-1 subunit (CAPZ alpha-1)
    • gi|595917|gb|AAC00566.1| (U16740) capping protein alpha 1 subunit [Mus musculus]
    • gi|6671672|ref|NP_031630.1|_1:286 (NM_007604) capping protein alpha 2 [Mus musculus]
    • gi|20341884|ref|XP_109468.1| (XM_109468) capping protein alpha 2 [Mus musculus]
    • gi|20914986|ref|XP_132993.1| (XM_132993) capping protein alpha 2 [Mus musculus]
    • gi|1345696sp|P47754|CAZ2_MOUSE F-actin capping protein alpha-2 subunit (CAPZ alpha-2)
    • gi|595919|gb|AAC00567.1| (U16741) capping protein alpha 2 subunit [Mus musculus]
    • gi|5453599|ref|NP_006127.1|_1:286 (NM_006136) capping protein (actin filament) muscle Z-line, alpha 2; F-actin capping protein alpha-2 subunit [Homo sapiens]
    • gi|1345695sp|P47755|CAZ2_HUMAN F-actin capping protein alpha-2 subunit (CapZ alpha-2)
    • gi|595255|gb|AAA88848.1| (U03269) actin capping protein alpha subunit [Homo sapiens]
    • gi|2393732|gb|AAC60382.1| (AC002543) f-actin capping protein alpha-2 subunit [Homo sapiens]
    • gi|13529131|gb|AAH05338.1|AAH05338 (BC005338) capping protein (actin filament) muscle Z-line, alpha 2 [Homo sapiens]
    • gi|12842248|dbj|BAB25530.1|_5:289 (AK008204) capping protein alpha 2~data source:MGD, source key:MGI:106222, evidence:ISS~putative [Mus musculus]
    • gi|12841166|dbj|BAB25102.1|_1:281 (AK007550) capping protein alpha 2~data source:MGD, source key:MGI:106222, evidence:ISS~putative [Mus musculus]
    • gi|20888881|ref|XP_140715.1|_1:272 (XM_140715) similar to F-actin capping protein alpha-1 subunit (CAPZ alpha-1) [Mus musculus]
    • gi|21298686|gb|EAA10831.1|_29:315 (AAAB01008960) agCP5596 [Anopheles gambiae str. PEST]
    • gi|115594sp|P25229|CAPA_XENLA_2:256 ACTIN-BINDING PROTEIN CHAIN A (ABP-A)
    • gi|85705|pir||S07105 actin-binding protein chain a, nuclear - African clawed frog (fragment)
    • gi|64909|emb|CAA35948.1| (X51605) nuclear actin-binding protein chain a [Xenopus laevis]
    • gi|226575|prf||1602248A nuclear actin binding protein [Xenopus sp.]
    • gi|13385206|ref|NP_080019.1|_1:283 (NM_025743) RIKEN cDNA 4933400A11 [Mus musculus]
    • gi|12854538|dbj|BAB30063.1| (AK015979) data source:SPTR, source key:P47753, evidence:ISS~putative~similar to F-ACTIN CAPPING PROTEIN ALPHA-1 SUBUNIT (CAPZ) (FRAGMENT) [Mus musculus]
    • gi|12855403|dbj|BAB30324.1| (AK016585) data source:SPTR, source key:P47753, evidence:ISS~putative~similar to F-ACTIN CAPPING PROTEIN ALPHA-1 SUBUNIT (CAPZ) (FRAGMENT) [Mus musculus]
    • gi|19922662|ref|NP_611539.1|_4:284 (NM_137695) CG10540 gene product [Drosophila melanogaster]
    • gi|11131875sp|Q9W2N0|CAPA_DROME F-actin capping protein alpha subunit
    • gi|7291228|gb|AAF46660.1| (AE003452) CG10540-PA [Drosophila melanogaster]
    • gi|17861504|gb|AAL39229.1| (AY069084) GH10050p [Drosophila melanogaster]
    • gi|6671674|ref|NP_031631.1|_5:273 (NM_007605) capping protein alpha 3 [Mus musculus]
    • gi|11131722sp|P70190|CAZ3_MOUSE F-actin capping protein alpha-3 subunit (CAPZ alpha-3) (Germ cell-specific protein 3)
    • gi|1517812|dbj|BAA13409.1| (D87471) gsg3 [Mus musculus]
    • gi|5295996|dbj|BAA81887.1| (AB026984) actin capping protein alpha [Mus musculus]
    • gi|12855098|dbj|BAB30213.1|_5:273 (AK016391) capping protein alpha 3~data source:MGD, source key:MGI:106221, evidence:ISS~putative [Mus musculus]
    • gi|8393045|ref|NP_058860.1|_5:273 (NM_017164) capping protein alpha 3 [Rattus norvegicus]
    • gi|11131487sp|Q9WUV6|CAZ3_RAT F-actin capping protein alpha-3 subunit (CAPZ alpha-3)
    • gi|4689021|emb|CAA73137.1| (Y12538) actin-capping protein, alpha subunit [Rattus norvegicus]
    • gi|20857911|ref|XP_129969.1|_2:228 (XM_129969) similar to F-actin capping protein alpha-1 subunit (CAPZ alpha-1) [Mus musculus]
    • gi|15277417|ref|NP_201585.1|_5:273 (NM_033328) capping protein alpha 3 [Homo sapiens]
    • gi|20137887sp|Q96KX2|CAZ3_HUMAN F-actin capping protein alpha-3 subunit (CapZ alpha-3) (GSG3)
    • gi|14625437|dbj|BAB61901.1| (AB053259) hGSG3 [Homo sapiens]
    • gi|16554245|dbj|BAB71703.1| (AK058174) unnamed protein product [Homo sapiens]
    • gi|16876933|gb|AAH16745.1|AAH16745_5:273 (BC016745) capping protein alpha 3 [Homo sapiens]
    • gi|17539460|ref|NP_501145.1|_3:281 (NM_068744) D2024.6.p [Caenorhabditis elegans]
    • gi|461690sp|P34685|CAPA_CAEEL F-ACTIN CAPPING PROTEIN ALPHA SUBUNIT
    • gi|542462|pir||A47734 F actin-capping protein alpha chain - Caenorhabditis elegans
    • gi|6686|emb|CAA79269.1| (Z18805) capping protein alpha subunit [Caenorhabditis elegans]
    • gi|6688|emb|CAA79305.1| (Z18853) capping protein alpha subunit [Caenorhabditis elegans]
    • gi|1086616|gb|AAA82286.1| (U41011) C. elegans CAP-1 protein (corresponding sequence D2024.6) [Caenorhabditis elegans]
    • gi|11279632|pir||T51820_6:301 F-actin capping protein alpha chain [imported] - Arabidopsis thaliana
    • gi|3702368|emb|CAA05054.1| (AJ001855) alpha subunit of F-actin capping protein [Arabidopsis thaliana]
    • gi|17488599|gb|AAL40366.1|AC091727_2_223:449 (AC091727) capping protein (actin filament) muscle Z-line, alpha 2 [Takifugu rubripes]
    • gi|15230004|ref|NP_187203.1|_6:301 (NM_111425) alpha subunit of F-actin capping protein [Arabidopsis thaliana]
    • gi|20141194sp|O82631|CAPA_ARATH F-actin capping protein alpha subunit (CapZ-alpha)
    • gi|7596760|gb|AAF64531.1| (AC009606) alpha subunit of F-actin capping protein [Arabidopsis thaliana]
    • gi|20893619|ref|XP_135071.1|_2:227 (XM_135071) similar to F-actin capping protein alpha-1 subunit (CAPZ alpha-1) [Mus musculus]
    • gi|19697393|gb|AAL93031.1|AC116032_20_3:279 (AC116032) F-actin capping protein alpha subunit [Dictyostelium discoideum]
    • gi|115593sp|P13022|CAPA_DICDI_3:279 F-ACTIN CAPPING PROTEIN ALPHA SUBUNIT (CAP34)
    • gi|483087|pir||B61042 Ca2+-independent f-actin-capping protein 34K chain - slime mold (Dictyostelium discoideum)
    • gi|167682|gb|AAA33176.1| (M25132) CAP34 protein [Dictyostelium discoideum]
    • gi|20137534sp|Q9P5K9|CAPA_NEUCR_5:265 Probable F-actin capping protein alpha subunit
    • gi|16945430|emb|CAB91688.2| (AL356172) probable actin-capping protein alpha-2 chain [Neurospora crassa]
    • gi|18553392|ref|XP_092658.1|_1:195 (XM_092658) similar to F-actin capping protein alpha-1 subunit (CapZ alpha-1) [Homo sapiens]
    • gi|6322845|ref|NP_012918.1|_1:262 (NC_001143) capping - addition of actin subunits; Cap1p [Saccharomyces cerevisiae]
    • gi|115595sp|P28495|CAPA_YEAST F-ACTIN CAPPING PROTEIN ALPHA SUBUNIT
    • gi|419820|pir||S30135 actin-capping protein alpha chain - yeast (Saccharomyces cerevisiae)
    • gi|3444|emb|CAA43669.1| (X61398) Capping Protein Alpha Subunit [Saccharomyces cerevisiae]
    • gi|485981|emb|CAA81841.1| (Z28007) ORF YKL007w [Saccharomyces cerevisiae]
    • gi|1680604|gb|AAC60553.1|S59773_2 (S59773) CAP1 gene product [Saccharomyces cerevisiae]
    • gi|19115551|ref|NP_594639.1|_3:252 (NC_003424) f-actin capping protein alpha subunit. [Schizosaccharomyces pombe]
    • gi|1705588sp|Q10434|CAPA_SCHPO Probable F-actin capping protein alpha subunit
    • gi|7490550|pir||T37574 f-actin capping protein alpha subunit - fission yeast (Schizosaccharomyces pombe)
    • gi|1262420|emb|CAA94697.1| (Z70721) f-actin capping protein alpha subunit. [Schizosaccharomyces pombe]
    • gi|17459523|ref|XP_066489.1|_10:141 (XM_066489) similar to capping protein (actin filament) muscle Z-line, alpha 1 [Homo sapiens]
    • gi|18595336|ref|XP_093063.1|_1:97 (XM_093063) similar to F-actin capping protein alpha-1 subunit (CapZ alpha-1) [Homo sapiens]
    • gi|13278139|gb|AAH03915.1|AAH03915_9:92 (BC003915) Similar to capping protein (actin filament) muscle Z-line, alpha 2 [Mus musculus] 
              10        20        30         40        50        60    
              |         |         |          |         |         |    
   1 MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNMDQFTP
   2 MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNMDQFTP
   3 MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNMDQFTP
   4 MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNMDQFTP
   5 MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNLDQFTP
   6 MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNMDQFTP
   7 ---FEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNMDQFTP
   8 MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNLDQFTP
   9 MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNLDQFTP
  10 -ADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNLDQFTP
  11 ---LEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNLDQFTP
  12 MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLL.PNNDNLLREGAAHAFAQYNLDQFTP
  13 MADFEDRVSDEEKVCVITKFITHAPPGEFNEVFNDAWLL.LNNGNLLREGAARAFAQNNMDQFTP
  14 MADVDDVISDQDKIRIASDFLMHAPPGEFNEVFNDVREL.LNDDRLLKEGASAACAQYNKDQLTP
  15 -------------------------------VFNDVRLL.LNNDNLLREGAAHAFAQYNMDQFTP
  16 MANRKDKASDEKKIDIASKFIKQAPPGEFKEVFHDIRQL.VNNDNLLKKRIGQAIAQYNMHQFTP
  17 -----TPITDAEKVRIVSDFILHAPPGEFNEVFNDVREL.LKNDTLLKDGASHAFAQYNKDQLTP
  18 ------VLSRKEKEKVIHRLLVQAPPGEFVNAFDDLCLL.IRDEKLMHHQGECAGHQHCQKYCVP
  19 ------VLSRKEKEKVIHRLLVQAPPGEFVNAFDDLCLL.IRDEKLMHHQGECAGHQHCQKYCVP
  20 ------VLSRQDKEKVIHRLLIQAPPGEFVNAFDDLCLL.IRDEKLMHHQGECAGHQHCQKYCVP
  21 ---------------------------------------.--------------------DQFTP
  22 ------VLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLL.IRDEKLMHHQGECAGHQHCQKYSVP
  23 ------VLSRKEKEKVIHRLLVQAPPGEFVNAFDDLCLL.IRDEKLMHHQGECAGHQHCQKYCVP
  24 ------VLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLL.IRDEKLMHHQGECAGHQHCQKYSVP
  25 ------EISDAEKVRIASDFIKHAPPGEFNEVFNSVRML.LENDDLLKNKCVNAIAQYNVGQFVP
  26 DELLETELSYDQKKEIAKWFFLNAPAGEINYVAKDLKAV.LSDEEVYNEAAMEAFPVYNKTHMIC
  27 --------------------------------------L.ITAQEPNNIPVPRAFAQYNLDQFTP
  28 DELLETELSYDQKKEIAKWFFLNAPAGEINYVAKDLKAV.LSDEEVYNEAAMEAFPVYNKTHMIC
  29 ---------------------------------------.--------------------DQFTP
  30 --------SNQELVQIATNFLLNAPPCEFMEVVSDVRAL.LPSESLLNASAGSTFREYNTSQMVS
  31 --------SNQELVQIATNFLLNAPPCEFMEVVSDVRAL.LPSESLLNASAGSTFREYNTSQMVS
  32 -------------KEIVSSFVEGAPPGEL----SDIKAL.TSSTPNLLNELGPAFQKYNEEQFTT
  33 MANFNDCVLDKEKVCIAAKFITHAPAGEFNEVFSDIRLL.CNNDSLLRERAARAFAHYNMDQFTP
  34 -------MSSSKFEEVINKIINDSPPGELREVYDDLIKI.TSENS--KNTILDAIENYNVQNCIP
  35 -------------KEAIYKLIRESPPGEVNQVVHDIRDIgLSDEEAIHEQL----KLYHEDYNSS
  36 ---------------------------------------.-----------------FNEKHRVP
  37 ---------------------------------------.-------------------------
  38 --DLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLL.LNNDNLLREGAAHAFAQYNLDQFTP
  39 MDDFDDCVTDEETVGMAAKFTTHAPPEEFNEAFNDVRLL.LNNDK--------------------
  40 ---------------------------------------.-------------------------


          70        80        90       100       110             120   
          |         |         |         |         |               |   
   1 VKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPED..TES....ALKQWRDA
   2 VKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEE..ADG....GLKSWRES
   3 VKIEGYDDQVLITEHGDLGNSRFLDPRNQISFKFDHLRKEASDPQPED..VDG....GLKSWRES
   4 VKIEGYDDQVLITEHGDLGNSRFLDPRNQISFKFDHLRKEASDPQPED..VDG....GLKSWRES
   5 VKIDGYDEQVLITEHGDLGNGKFLDPKNKISFKFDHLRKEATDPRPHE..VEN....AIESWRNS
   6 VKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPED..TES....ALKQWRDA
   7 VKIEGYDDQVLITEHGDLGNSRFLDPRNQISFKFDHLRKEASDPQPED..VDG....GLKSWRES
   8 VKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPYE..AEN....AIESWRTS
   9 VKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCE..VEN....AVESWRTS
  10 VKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPYE..AEN....AIESWRTS
  11 VKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCE..VEN....AVESWRTS
  12 VKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPYE..AEN....AIESWRTS
  13 VKIEGYDDQVLTTEHCDLGNSRFLDPRNKISFKFDHLQKEASDQPPED..VDG....GLRSWRES
  14 VILENSELAVLITEFNDLGGGRFFDPRTKQSFKFDHLRKEASDLQNHD..GDH....TSEQWRAM
  15 AKIEGYDDQVLITEHGDLGNSRFLDPRNRITFKFDHLRKEASDPHPDD..SDV....ALKSWRDA
  16 VRIEGYDDHVLVTEHGHLGNNRFFDPRNRVSFKFDHLKKTISNLQLGL..TDG....NLTYLRES
  17 VRIEGTDHNAIISEHNDLGNGRFYDPRTKQAFKYDHLRKEASDYQDVE..ADA....TAEPWRAA
  18 LCIDG--NPVLLSHHNVMGDFRFFDYQSKLSFRFDLLQNQLRDIQSHGi.IRN....ETEYLRSV
  19 LCIDG--NPVLLSHHNVMGDFRFFDYQSKLSFRFDLLQNQLRDIQSHGi.IRN....ETEYIRSV
  20 LCIDG--NPVLLSHHNVMGDFRFFDYQSKLSFRFDLLQNQLRDIQSHGi.IRN....ENEYLRSV
  21 VKIEGYDDQVLITEHGDLGNSRFLDPRNQISFKFDHLRKEASDPQPED..VDG....GLKSWRES
  22 LCIDG--NPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGi.IQN....EAEYLRVV
  23 LCIDG--NPVLLSHHNVMGDFRFFDYQSKLSFRFDLLQNQLRDIPSHGi.IRN....ETEYLRSV
  24 LCIDG--NPVLLSHHNVMGDYRFFDHQSKLSFKYYLLQNQLKDIQSHGi.IQN....EAEYLRVV
  25 VKLDGVAKQTLITPYNDLGNGRFYDEVSKKSFKYDHVRKEAADLQPHP..AESg...ITEQWRQA
  26 LEMPSGAGDVIVSSYSEINENEYLDPRTAQVAIVDHVKQICTKVRPAN..DEElpslYIEEYRYA
  27 VKIEGYEEQVLITEHGDLGNGRVLDPKNKISFRFDHLRKEASDPQPHD..VDG....SIESWRTA
  28 LEMPSGAGDVIVSSYSEINENEYLDPRTAQVAIVDHVKQICTKVRPAN..DEElpslYIEEYRYA
  29 VKIEGYDDQVLITEHGDLRNSRFSDPRNKTSFKFDHLRKEASDQQPED..VDG....GLKSWRES
  30 VQTSK--GSALITKEGEISNNEYLDSKNKQVITYDHIKQEVTGERSASgeIEQ....DIEQYRAA
  31 VQTSK--GSALITKEGEISNNEYLDPKNKQVITYDHIKQEVTGERSASgeIEQ....DIEQYRAA
  32 VKLPGGSQPVIISSHSSLEDGRYYDVESSSSFAYDHITQKASDVQSHV..LEG....EQTDLVKS
  33 VKMEGCEDQ---------------------------------------..---....--------
  34 IEVNG--NSVIISKYNK-EGAKFFDPVNSVIFSVNHLERKGLDIEPYE..FTHak..IEKGQLKE
  35 VSISD-DEKVIISADNRLEGNRYYDQVLQKSFTINYETMEAENVEDYT..---....EAIKIPDE
  36 AAKGE--ERYLVSEYNK-SGSKYFDPVNKVLFAVDHITREASDIEEYT..SED....-ATQVQSD
  37 ------------------GNSRFLDPRNKISFKFDHVWKKASDPQPQE..VDG....--------
  38 VKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPYE..AXN....AVE-----
  39 ------------------------------------------------..---....--------
  40 ------------------------------------------------..---....--------


          130       140            150       160       170       180   
           |         |              |         |         |         |   
   1 CDSALRAYVKDHYPNGFCTVYGKS.....IDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTI..
   2 CDSALRAYVKDHYSNGFCTVYAKT.....IDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTI..
   3 CDSALRAYVKDHYSNGFCTVYAKT.....IDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTI..
   4 CDSALRAYVKDHYSNGFCTVYAKT.....IDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTI..
   5 VETAMKAYVKEHYPNGVCTVYGKT.....IDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTI..
   6 CDSALRAYVKDHYPNGFCTVYGKS.....IDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTI..
   7 CDSALRAYVKDHYSNGFCTVYAKT.....IDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTI..
   8 VETALRAYVKEHYPNGVCTVYGKK.....VDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTV..
   9 VETALRAYVKEHYPNGVCTVYGKK.....IDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTI..
  10 VETALRAYVKEHYPNGVCTVYGKK.....VDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTV..
  11 VETALRAYVKEHYPNGVCTVYGKK.....IDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTI..
  12 VETALRAYVKEHYPNGVCTVYGKK.....VDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTV..
  13 CDSALRAYVKDHYSNGFCTVYTKT.....IDRQQSIIACIESHQFQPKNFWNGHWRSEWKFTI..
  14 LDIETLTYSANHYRNGSCSVFGRT.....VNGQITLNVCIEDHQFQPKNFWNGRWRSVWAITFpa
  15 CDLALRAYVKEHYPNGVCTVYGKT.....IDGQQTIVSCIESHQFQPKNFWNGRWRSEWKFTI..
  16 CDKALKAYMKQYYSTGFSTVYGKT.....IQGKKTIIACIESHQFQPQTFWNGSWRSQWKLTI..
  17 LDLETLAYTASHYRHGVSSVFGKA.....QGNQITLTICIEDHQFQPKNYWNGRWRSQWHVTFqa
  18 VMCALKLYVNDHYPNGNCNVLRKT.....VKSKEFLIACIEDHSYDNGECWNGLWKSKWIFQV..
  19 VMCALKLYVNDHYPNGNCNVLRKT.....VKSKEFLIACIEDHSYDNGECWNGLWKSKWIFQV..
  20 VMCALKLYVNDHYPNGNCNVLRKT.....VKNKEFLIACIEKHSYDNGECWNGLWKSKWIFQV..
  21 CDSALRAYVKDHYSNGFCTVYAKT.....IDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTI..
  22 LLCALKLYVNDHYPKGNCNMLRKT.....VKSKEYLIACIEDHNYETGECWNGLWKSKWIFQV..
  23 VMCALKLYVNDHYPNGNCNVLRKT.....VKSKEFLIACIEDHSIDNGECWNGLWKSKWIFQV..
  24 LLCALKLYVNDHYPKGNCNMLRKT.....VKSKEYLIACIEDHNYETGECWNGLWKSKWIFQV..
  25 LQTQLDIYIDDHYAKSGTGVVFAR.....NG---VFTICIESHQFQPKNFCNGRWRSEWNVPV..
  26 LDAEIQRYVSESYPKGMSAVNCVKgk6egPGSDFELVVIITAMRLSPQNFCNGSWRSVWNIDF..
  27 VDSAVRAYVKEHYPNGVCTIYGKT.....IDGQQTIIVCIECHQFQPKNFWNGRWRSEWKFTI..
  28 LDAEIQRYVSESYPKGMSAVNCVKgk6egPGSDFELVVIITAMRLSPQNFCNGSWRSVWNIDF..
  29 CDSALRAYVKDHHSNGFCTVYAKT.....IDGQQTITACIESHQFQPKNFWNGRWRSGWKFTI..
  30 FDEEATKYCNEYYPNGVSAVYGTK.....VSEGIKITVCISTCIYKPNAFYSGRWRSVWTCTF..
  31 FDEEATKYCNEYYPNGVSAVYGTK.....VSEGIKITVCISTCIYKPNAFYSGRWRSVWTCTF..
  32 TVKGLSAYVKEHFPNAAYGAYP--.....IENDTKVAVVIVANKYSPNNFWNGRWRSLYIYDP..
  33 ------------------------.....-----TIIACIESHECQPKNFWNGRWRSEWKFTI..
  34 LHDKLHEYLLQSFPGDVSFAVYPV.....PEEISKISIIIVSTKYNPNNFWNGHWRSSYIYDL..
  35 IVKQIKKVASDHYLSDVTFGIIKK.....SDEVESFTIVLVSSKYNPKNYWNGSWRCICNYNV..
  36 LYDELSKSVSNFFPDTAVFNVFKI.....PESDQYAIIVV-SNKKSLGDFWTGYWLSEYVYDV..
  37 ------------------------.....----------------------------------..
  38 ------------------------.....----------------------------------..
  39 ------------------------.....----------------------------------..
  40 ------------------------.....----------------------------------..


                    190       200       210       220        230       
                     |         |         |         |          |       
   1 .TPP...TA..QVA..AVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQ.TAKEFIKIIENAEN
   2 .TPP...TA..QVV..GVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQ.TAKEFIKIIENAEN
   3 .TPP...SA..QVV..GVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEIQ.TTKEFIKIIESAEN
   4 .TPP...SA..QVV..GVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEVQ.TTKEFIKIIESAEN
   5 .SPS...TT..QVA..GILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEAQ.TAKEFIKIVEAAEN
   6 .TPP...TA..QVA..AVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQ.TAKEFIKIIENAEN
   7 .TPP...SA..QVV..GVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEIQ.TTKEFIKIIESAEN
   8 .TPS...TT..QVV..GILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQ.TAKEFIKIVEAAEN
   9 .TPS...TT..QVV..GILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQ.TAKEFIKIVEAAEN
  10 .TPS...TT..QVV..GILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQ.TAKEFIKIVEAAEN
  11 .TPS...TT..QVV..GILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQ.TAKEFIKIVEAAEN
  12 .TPS...TT..QVV..GILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQ.TAKEFIKIVEAAEN
  13 .TPP...SA..QVA..GVLKIQ----------LVSHKDVQDSVTVSNEVQ.TAKELIKIMKSAEN
  14 tGGG...TA..ELK..GSLKLQVHYYEDGNVQLVSAKDCRETVPITNEAN.TAKEIIRLIEESEH
  15 .SGS...TA..QLV..GVLKIQVHYYEDGNVQLVSHKDVQESITISGEAQ.TAKEFVKIIEQAES
  16 .TPP...TA..QVI..GMLKSHVHYYENGNIQLVVHKDVHESLTVINEDQ.TAKVFIKIIEMVEN
  17 .GSG...TA..ELK..GVLKVQVHYYEDGNVQLVSSKECRESVVVSNEQQ.VAKEVIRLIEDAEN
  18 .NPF...LT..QVT..GRIFVQAHFFRCVNLHIEVSKDLKESLEVVNQAQ.LALSFARLVEEQEN
  19 .NPF...LT..QVT..GRIFVQAHFFRCVNLHIEVSKDLKESLEVVNQAQ.LALSYARLVEEQEN
  20 .NPF...LT..QVT..GRIFVQAHYFRCVNLHVEVSKDLKESLEVVNQAQ.LALSFARLVEEQEN
  21 .TPP...SA..QVV..GVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEVQ.TTKEFIKIIESAEN
  22 .NPF...LT..QVT..GRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQ.LALSFARLVEEQEN
  23 .NPF...LT..QVT..VRIFVQAHFFRCVNLHIEVSKDLKESLEVVNQAQ.LALSFARLVEEQEN
  24 .NPF...LT..QVT..GRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQ.LALSFARLVEEQEN
  25 .GDGksgSQ..EMK..GKILSQVHYYEDGNVQLFSEKEPVLKVNVSADFDkTAKEIIHAISEEET
  26 .QDE...SQvlDIK..GKLQVGAHYFEEGNVELDAKKDFQDSTIFQSADD.CAIAIANIIRHHET
  27 .SSS...ST..EVA..GIMKIQVHYYEDGNVQLVSHKEVQDSMSIS----.--------------
  28 .QDE...SQvlDIK..GKLQVGAHYFEEGNVELDAKKDFQDSTIFQSADD.CAIAIANIIRHHET
  29 .TPP...SA..QV-..GVLKIQVRCYEDGNVQLVSHKGVQDSVTVSNEVQ.TTKEFIKIIESAEN
  30 .KPG...SG..NVTsnGKVQVNVHYFEDGNVQLNTVTQKQTTSPSADAQS.TAVNAFKAIGKAEL
  31 .KPG...SG..NVTsnGKVQVNVHYFEDGNVQLNTVTQKQTTSPSADAQS.TAVNAFKAIGKAEL
  32 .SNN...S-..-IE..GSIKVDVHYYEDGNVRLLTNKTVTATV----SSG.TGSGIAKEISVNEK
  33 .TPP...TA..QVV..GVLKIQVHYYEDGSVQLVSHKDVQDSLTVSNDAQ.TAKEFIKIIENAEN
  34 .ET-...-R..ELS..GQISTQVHYYEDGNVSFQSGKDINQSNV------.--DDVVCTIRDIET
  35 .SE-...-K..KLE..GRSHIRVHYYEDGNVWLDASRPISATVEETS---.---KLYEVLAQVEN
  36 .DGD...T-..-IS..GEVSVDAHYFEDGNVRF-------KSTASLESAQ.TDSPIVSI-----K
  37 .---...-A..QVA..GVLKI--HYYEYGNVQSVSHKDVQDSLTVSNEVQ.TAKEFIKIIGNAEN
  38 .---...--..---..----------------------------------.--------------
  39 .---...--..---..----------------------------------.----------NAEN
  40 .---...--..---..-------------NVQLVSHKDVQDSVTVSNEVQ.TTKEFIKIIESAEN


      240       250        260       270         280      
       |         |          |         |           |      
   1 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
   2 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
   3 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
   4 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
   5 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
   6 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
   7 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
   8 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
   9 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
  10 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
  11 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
  12 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.IK.ILSYRWSK-----
  13 EYQTTISENYQTMSNTTF.KALRWQLPLTCTKIDW.NK.ILSYKIGKE----
  14 DYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.SK.IVSYSIGKELK--
  15 DYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
  16 GYQAALNENYHTISCTTF.KALRRQLPITYHKIDW.NK.ILSYKVCKEL---
  17 EYQLAISENYQTMSDTTF.KAMRRQLPITRTKIDW.SK.IVSYSIGKELK--
  18 KFQAAVIEELQELSNEALrKILRRDLPVTRTLIDW.QR.IL-----------
  19 KFQAAVIEELQELSNEALrKILRRDLPVTRTLIDW.QR.IL-----------
  20 KFQAAVIEELQELSNEALrKILRRDLPVTRTLIDW.QR.IL-----------
  21 EYQTAISENYQTMSDTAF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
  22 KFQAAVLEELQELSNEALrKILRRDLPVTRTLIDW.HR.IL-----------
  23 KFQAAVIEELQELSNEALrKILRRDLPVTRTLIDW.QR.ILS----------
  24 KFQAAVLEELQELSNEALrKILRRDLPVTRTLIDW.HR.IL-----------
  25 IYQNAVQENYANMSDTTF.KALRRQLPVTRAKMDW.NK.AQTYRIGQEM---
  26 EYLASLEVAYSKLPDNTF.KDLRRKLPVTRTLFPW.QN.TLQFSLTREVE--
  27 ---MAINENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA
  28 EYLASLEVAYSKLPDNTF.KDLRRKLPVTRTLFPW.QN.TLQFSLTREVE--
  29 EYQTAISENYQTMSDTTF.KALCRQLPVTRTKIDC.NK.ILSYKIGKEMQNA
  30 NLHTALDNNYSTMGDTTF.KALRRALPINRTKINW.QK.VKNFKIANEL---
  31 NLHTALDNNYSTMGDTTF.KALRRALPINRTKINW.QK.VKNFKIANEL---
  32 KYQEELNKSFTSLSEGAF.KGLRRQLPVTRQKIEW.DK.VASYRLGQDIGGG
  33 EYQTAISENCQTMSDTTF.KVLRRQLPVTRTKIDW.NK.I------------
  34 NFENDLDLSFFDLNEKQF.KALRRRLPVTRSKINW.GSaIGSYRLGK-----
  35 GIQQSFNVELSSLNDKKF.KELRRQLPVTRQKINW.EN.VSGIR--------
  36 QFEKNLINKFQYMNETQF.KGLRRRLPVTRAKINWgQG.IGNYRLGRD----
  37 DHQTATSENYQTMSDTTF.QALRRQLPVTRRKIDW.NK.ILIYQIGKEMQNA
  38 ------------------.----------------.--.-------------
  39 EYQTAISENYQTLSDTTF.KALCRQLPVTCTKIDW.NK.IVSYKIGKDMQNA
  40 EYQTAISENYQTMSDTTF.KALRRQLPVTRTKIDW.NK.ILSYKIGKEMQNA