PFRMAT SS TARGET T0161 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0161.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0161.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0161.t2k.str.rdb (weight 1.53983) METHOD T0161.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0161.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0161 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0161.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from T0161.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0161 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0161.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from T0161.t2k.str.rdb METHOD ============================================ METHOD TARGET T0161 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0161.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from T0161.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0161 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0161.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ MODEL 1 M C 0.88 S C 0.79 E H 0.49 T H 0.59 D H 0.66 L H 0.71 L H 0.74 L H 0.77 K H 0.75 M H 0.69 V H 0.58 R H 0.47 Q C 0.58 P C 0.58 V C 0.46 K C 0.36 L H 0.44 Y H 0.48 S H 0.46 V H 0.68 A H 0.72 T H 0.73 L H 0.74 F H 0.75 H H 0.77 E H 0.75 F H 0.81 S H 0.84 E H 0.84 V H 0.85 I H 0.82 T H 0.79 K H 0.74 L H 0.68 E H 0.63 H H 0.55 S H 0.48 V C 0.45 Q C 0.54 K C 0.58 E C 0.71 P C 0.68 T C 0.58 S C 0.50 L C 0.45 L C 0.51 S C 0.60 E H 0.52 E H 0.58 N H 0.57 W H 0.68 H H 0.77 K H 0.85 Q H 0.85 F H 0.86 L H 0.87 K H 0.85 F H 0.86 A H 0.82 Q H 0.74 A H 0.61 L C 0.59 P C 0.66 A C 0.61 H C 0.69 G C 0.76 S C 0.69 A C 0.52 S C 0.47 W H 0.41 L C 0.47 N C 0.59 L H 0.49 D H 0.62 D H 0.76 A H 0.83 L H 0.83 Q H 0.84 A H 0.81 V H 0.76 V H 0.61 G C 0.53 N C 0.61 S C 0.49 R H 0.68 S H 0.77 A H 0.84 F H 0.85 L H 0.89 H H 0.91 Q H 0.91 L H 0.92 I H 0.91 A H 0.89 K H 0.84 L H 0.74 K H 0.67 S H 0.59 R H 0.51 H C 0.43 L C 0.37 Q E 0.36 V E 0.50 L E 0.50 E E 0.49 L C 0.34 N C 0.49 K C 0.56 I C 0.66 G C 0.78 S C 0.78 E C 0.78 P C 0.71 L C 0.68 D C 0.68 L C 0.53 S C 0.60 N C 0.69 L C 0.80 P C 0.79 A C 0.74 P C 0.61 F E 0.47 Y E 0.65 V E 0.70 L E 0.63 L C 0.58 P C 0.63 E H 0.52 S H 0.57 F H 0.63 A H 0.66 A H 0.65 R H 0.61 I H 0.53 T H 0.53 L H 0.45 L E 0.42 V H 0.39 Q C 0.41 D C 0.54 K C 0.59 A C 0.62 L C 0.68 P C 0.60 Y E 0.49 V E 0.67 R E 0.75 V E 0.72 S E 0.65 F E 0.56 E E 0.49 Y E 0.44 W C 0.48 H C 0.72 A C 0.92 END