PFRMAT SS TARGET T0160 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0160.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0160.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0160.t2k.str.rdb (weight 1.53983) METHOD T0160.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0160.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0160 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0160.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 81 METHOD METHOD ============================================ METHOD Comments from T0160.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0160 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0160.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 81 METHOD METHOD ============================================ METHOD Comments from T0160.t2k.str.rdb METHOD ============================================ METHOD TARGET T0160 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0160.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 81 METHOD METHOD ============================================ METHOD Comments from T0160.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0160 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0160.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 81 METHOD METHOD ============================================ MODEL 1 G C 0.91 S C 0.85 H C 0.80 M C 0.75 A C 0.79 K C 0.82 H C 0.84 E C 0.80 Q C 0.76 I E 0.49 L E 0.80 V E 0.84 L E 0.82 D C 0.58 P C 0.83 P C 0.81 S C 0.75 D C 0.52 L E 0.82 K E 0.86 F E 0.80 K E 0.64 G C 0.55 P C 0.76 F C 0.82 T C 0.86 D C 0.81 V C 0.56 V E 0.74 T E 0.83 T E 0.88 N E 0.90 L E 0.92 K E 0.92 L E 0.91 Q E 0.85 N E 0.64 P C 0.80 S C 0.87 D C 0.84 R C 0.76 K E 0.59 V E 0.79 C E 0.89 F E 0.90 K E 0.92 V E 0.90 K E 0.85 T E 0.72 T C 0.66 A C 0.80 P C 0.78 R C 0.71 R E 0.59 Y E 0.75 C E 0.84 V E 0.80 R E 0.54 P C 0.74 N C 0.79 S C 0.64 G C 0.55 V E 0.73 I E 0.75 D C 0.73 P C 0.88 G C 0.93 S C 0.76 I E 0.58 V E 0.88 Y E 0.91 V E 0.92 S E 0.93 V E 0.92 M E 0.89 L E 0.76 Q C 0.56 P C 0.75 F C 0.79 D C 0.77 Y C 0.76 D C 0.83 P C 0.79 N C 0.72 E C 0.69 K C 0.66 S C 0.64 K C 0.73 H C 0.67 K E 0.78 F E 0.90 M E 0.92 V E 0.93 Q E 0.91 T E 0.90 I E 0.81 F E 0.68 A C 0.68 P C 0.84 P C 0.85 N C 0.84 I C 0.62 S C 0.53 D H 0.50 M H 0.80 E H 0.89 A H 0.93 V H 0.93 W H 0.92 K H 0.88 E H 0.77 A H 0.57 K C 0.72 P C 0.83 D C 0.84 E C 0.75 L C 0.54 M E 0.68 D E 0.82 S E 0.83 K E 0.85 P E 0.83 R E 0.86 C E 0.88 V E 0.88 F E 0.86 E E 0.72 M C 0.90 END