PFRMAT SS TARGET T0156 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0156.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0156.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0156.t2k.str.rdb (weight 1.53983) METHOD T0156.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0156.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0156 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0156.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 47 METHOD METHOD ============================================ METHOD Comments from T0156.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0156 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0156.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 47 METHOD METHOD ============================================ METHOD Comments from T0156.t2k.str.rdb METHOD ============================================ METHOD TARGET T0156 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0156.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 47 METHOD METHOD ============================================ METHOD Comments from T0156.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0156 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0156.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 47 METHOD METHOD ============================================ MODEL 1 M C 0.82 A C 0.66 I C 0.59 S C 0.58 F C 0.65 R C 0.77 P C 0.81 T H 0.51 A H 0.77 D H 0.82 L H 0.87 V H 0.84 D H 0.85 D H 0.80 I H 0.70 G H 0.59 P H 0.57 D H 0.53 V C 0.52 R C 0.57 S C 0.48 C C 0.51 D C 0.55 L C 0.53 Q C 0.52 F C 0.55 R C 0.64 Q C 0.66 F C 0.72 G C 0.78 G C 0.81 R C 0.80 S C 0.61 Q E 0.56 F E 0.70 A E 0.68 G E 0.60 P E 0.69 I E 0.83 S E 0.90 T E 0.91 V E 0.90 R E 0.87 C E 0.69 F C 0.75 Q C 0.88 D C 0.85 N C 0.73 A H 0.58 L H 0.71 L H 0.85 K H 0.88 S H 0.88 V H 0.90 L H 0.89 S H 0.85 Q H 0.63 P C 0.77 S C 0.89 A C 0.88 G C 0.91 G C 0.59 V E 0.88 L E 0.92 V E 0.92 I E 0.87 D C 0.53 G C 0.85 A C 0.92 G C 0.90 S C 0.79 L C 0.43 H H 0.49 T H 0.64 A H 0.67 L H 0.65 V H 0.81 G H 0.89 D H 0.94 V H 0.95 I H 0.96 A H 0.96 E H 0.96 L H 0.96 A H 0.96 R H 0.95 S H 0.90 T C 0.62 G C 0.94 W C 0.88 T C 0.57 G E 0.88 L E 0.93 I E 0.92 V E 0.89 H C 0.50 G C 0.75 A C 0.57 V C 0.47 R C 0.58 D C 0.69 A H 0.89 A H 0.92 A H 0.93 L H 0.92 R H 0.87 G H 0.65 I C 0.64 D C 0.90 I C 0.87 G C 0.66 I E 0.59 K E 0.70 A E 0.66 L E 0.49 G C 0.58 T C 0.58 N C 0.69 P C 0.71 R C 0.70 K C 0.70 S C 0.66 T C 0.63 K C 0.60 T C 0.69 G C 0.71 A C 0.68 G C 0.62 E C 0.55 R C 0.53 D C 0.59 V C 0.50 E E 0.66 I E 0.86 T E 0.86 L E 0.70 G C 0.80 G C 0.80 V E 0.55 T E 0.77 F E 0.69 V C 0.71 P C 0.85 G C 0.87 D C 0.51 I E 0.89 A E 0.92 Y E 0.91 S E 0.88 D C 0.49 D C 0.79 D C 0.89 G C 0.69 I E 0.71 I E 0.89 V E 0.84 V C 0.79 END