a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0152 Hypothetical protein Rv1347c, Mycobacterium tuberculosis H37Rv
- gi|1389801|gb|AAC46343.1|_6:196 (U59183) aminoglycoside 6'-N-acetyltransferase [Pseudomonas aeruginosa]
- gi|4105087|gb|AAD02244.1|_6:196 (AF043381) aminoglycoside 6'-N-acetyltransferase [Pseudomonas aeruginosa]
- gi|112953|sp|P20092|AAC6_SERMA_7:194 Aminoglycoside N(6')-acetyltransferase (AAC(6'))
- gi|79142|pir||A28388 aminoglycoside N6'-acetyltransferase (EC 2.3.1.82) - Serratia marcescens
- gi|152816|gb|AAA26550.1| (M23634) acetyltransferase [Serratia marcescens]
- gi|19774238|ref|NP_608307.1|_8:194 (NC_003486) aminoglycoside 6'-N-acetyltransferase type Ib [Klebsiella pneumoniae]
- gi|112952|sp|P19650|AAC6_KLEPN Aminoglycoside N(6')-acetyltransferase (Amikacin resistance protein) (AAC(6'))
- gi|78946|pir||B31104 aminoglycoside N6'-acetyltransferase (EC 2.3.1.82) - Klebsiella pneumoniae transposon Tn1331
- gi|149162|gb|AAA69747.1| (M21682) aminoglycoside 6'-N-acetyltransferase [Plasmid pJHC-MW1]
- gi|155012|gb|AAA98404.1| (M55547) Aac [Klebsiella pneumoniae]
- gi|19698429|gb|AAL93141.1|AF479774_5 (AF479774) aminoglycoside 6'-N-acetyltransferase type Ib [Klebsiella pneumoniae]
- gi|2662452|gb|AAB88285.1|_8:194 (AF012280) mutant aminoglycoside 6'-N-acetyltransferase [Plasmid pJHC-MW1]
- gi|17981459|gb|AAL51021.1|AF453998_3_265:456 (AF453998) fused aminoglycoside (3'') adenylyltransferase-aminoglycoside (6') acetyltransferase ANT(3'')-Ih-AAC(6')-IId [Serratia marcescens]
- gi|14010259|gb|AAK51922.1|AF360378_1_8:194 (AF360378) mutant AAC6'-IbS158A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010285|gb|AAK51935.1|AF360391_1_8:194 (AF360391) mutant AAC6'-IbR173A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010255|gb|AAK51920.1|AF360376_1_8:194 (AF360376) mutant AAC6'-IbS156A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010263|gb|AAK51924.1|AF360380_1_8:194 (AF360380) mutant AAC6'-IbL160A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010265|gb|AAK51925.1|AF360381_1_8:194 (AF360381) mutant AAC6'-IbR161A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010257|gb|AAK51921.1|AF360377_1_8:194 (AF360377) mutant AAC6'-IbP157A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010277|gb|AAK51931.1|AF360387_1_8:194 (AF360387) mutant AAC6'-IbK168A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010269|gb|AAK51927.1|AF360383_1_8:194 (AF360383) mutant AAC6'-IbR164A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010283|gb|AAK51934.1|AF360390_1_8:194 (AF360390) mutant AAC6'-IbE172A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010275|gb|AAK51930.1|AF360386_1_8:194 (AF360386) mutant AAC6'-IbE167A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010287|gb|AAK51936.1|AF360392_1_8:194 (AF360392) mutant AAC6'-IbQ174A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010271|gb|AAK51928.1|AF360384_1_8:194 (AF360384) mutant AAC6'-IbC165A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010273|gb|AAK51929.1|AF360385_1_8:194 (AF360385) mutant AAC6'-IbY166A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010289|gb|AAK51937.1|AF360393_1_8:194 (AF360393) mutant AAC6'-IbG175A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010267|gb|AAK51926.1|AF360382_1_8:194 (AF360382) mutant AAC6'-IbI163A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010261|gb|AAK51923.1|AF360379_1_8:194 (AF360379) mutant AAC6'-IbN159A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|2662450|gb|AAB88284.1|_8:194 (AF012279) mutant aminoglycoside 6'-N-acetyltransferase [Plasmid pJHC-MW1]
- gi|14010279|gb|AAK51932.1|AF360388_1_8:194 (AF360388) mutant AAC6'-IbG170A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|18958401|gb|AAL82588.1|AF355189_2_124:327 (AF355189) aminoglycoside 3-N-acetyltransferase/aminoglycoside 6'-N-acetyltransferase fusion protein [Pseudomonas aeruginosa]
- gi|14010253|gb|AAK51919.1|AF360375_1_8:194 (AF360375) mutant AAC6'-IbP155A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14010281|gb|AAK51933.1|AF360389_1_8:194 (AF360389) mutant AAC6'-IbF171A 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|11282471|pir||T44480_102:310 conserved hypothetical protein iucB [imported] - Shigella flexneri
- gi|5532463|gb|AAD44747.1|AF141323_18 (AF141323) IucB [Shigella flexneri]
- gi|14626625|gb|AAK71632.1|AF335540_4_102:310 (AF335540) IucB [Shigella boydii]
- gi|21483831|gb|AAM52493.1|_6:185 (AY103455) aminoglycoside 6'-N-acetyl transferase [Vibrio cholerae]
- gi|15866618|gb|AAL10408.1|AF416297_3_3:181 (AF416297) AacA4 aminoglycoside (6') acetyltransferase [Serratia marcescens]
- gi|7716041|gb|AAF68256.1|AF207065_1_3:177 (AF207065) aminoglycoside 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|11345444|gb|AAG33663.1| (AY007784) aminoglycoside 6'-N-acetyltransferase Ib [Acinetobacter baumannii]
- gi|13094934|gb|AAK12086.1|AF318077_2 (AF318077) aminoglycoside 6'-N-acetyltransferase [Pseudomonas aeruginosa]
- gi|6685571|sp|Q47317|IUCB_ECOLI_102:310 AEROBACTIN SIDEROPHORE BIOSYNTHESIS PROTEIN IUCB
- gi|1073534|pir||S44019 aerobactin biosynthesis protein iucB [validated] - Escherichia coli plasmid ColV-K30
- gi|474191|emb|CAA53708.1| (X76100) iucB [Escherichia coli]
- gi|321939|pir||JC1322_3:177 aminoglycoside N6'-acetyltransferase (EC 2.3.1.82) - Serratia sp. (strain 45)
- gi|260513|gb|AAB24284.1| (S49888) aminoglycoside 6'-N-acetyltransferase; AAC(6') [Serratia sp.]
- gi|8118217|gb|AAF72941.1|AF231133_2 (AF231133) AAC(6')-Ib [Pseudomonas aeruginosa]
- gi|13344942|gb|AAK19123.1|AF263520_5 (AF263520) 6'-N-aminoglycoside acetyltransferase Ib' [Pseudomonas aeruginosa]
- gi|14906257|gb|AAK72474.1| (AY038837) aminoglycoside 6'-N-acetyltransferase [Acinetobacter baumannii]
- gi|17386063|gb|AAL38577.1|AF445082_4 (AF445082) aminoglycoside 6'-N-acetyltransferase [Acinetobacter baumannii]
- gi|21466159|gb|AAL35587.2|AF439785_1 (AF439785) aminoglycoside 6'-N-acetyltransferase [Campylobacter jejuni]
- gi|21466163|gb|AAL35588.2|AF439786_1 (AF439786) aminoglycoside 6'-N-acetyltransferase [Campylobacter jejuni]
- gi|4210825|emb|CAA11472.1|_3:177 (AJ223604) aacA4 [Pseudomonas aeruginosa]
- gi|14334212|gb|AAK59384.1| (AY033653) aminoglycoside 6'-N-acetyltransferase [Pseudomonas aeruginosa]
- gi|13925894|gb|AAK49459.1|AF315786_2_3:177 (AF315786) aminoglycoside acetyltransferase [Pseudomonas aeruginosa]
- gi|16902301|dbj|BAB71949.1|_3:177 (AB070224) aminoglycoside 6'-N-acetyltransferase [Serratia marcescens]
- gi|16121293|ref|NP_404606.1|_105:311 (NC_003143) putative siderophore biosynthesis protein IucB [Yersinia pestis]
- gi|15979059|emb|CAC89834.1| (AJ414145) putative siderophore biosynthesis protein IucB [Yersinia pestis]
- gi|2120611|pir||S67948_1:165 6'-N-aminoglycoside acetyltransferase - Pseudomonas aeruginosa (strain BM2656)
- gi|1906651|gb|AAC77498.1| (U90945) 6'-N-aminoglycoside acetyltransferase [Klebsiella oxytoca]
- gi|4539648|gb|AAD22142.1|AF034958_1 (AF034958) 6'-N-aminoglycoside acetyltransferase [Enterobacter aerogenes]
- gi|10444093|gb|AAG17706.1|AF282595_2 (AF282595) 6'-N-aminoglycoside acetyltransferase [Klebsiella pneumoniae]
- gi|18307533|emb|CAD20933.1| (AJ311891) 6'-N-aminoglycoside acetyltransferase Ib [Salmonella enterica subsp. enterica serovar Infantis]
- gi|21668214|emb|CAC85942.1| (AJ313334) aminoglycoside 6'-N-acetyltransferase [Acinetobacter baumannii]
- gi|21668217|emb|CAC85641.1| (AJ319747) aminoglycoside 6'-N-acetyltransferase [Acinetobacter baumannii]
- gi|3393055|emb|CAA08845.1|_1:165 (AJ009820) 6-N aminglycoside acetyltransferase [Salmonella typhimurium]
- gi|13272356|gb|AAK17118.1|AF302086_2_1:165 (AF302086) 6'-Ib' aminoglycoside acetyltransferase [Pseudomonas aeruginosa]
- gi|9454103|gb|AAF87684.1|AF227505_1_1:165 (AF227505) aminoglycoside 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14017422|gb|AAK50435.1| (AY029772) aminoglycoside acetyltransferase-6' type I AACA4 [Pseudomonas aeruginosa]
- gi|14133995|gb|AAK54201.1|AF369871_3 (AF369871) aminoglycoside 6'-acetyltransferase type I [Acinetobacter genomosp. 3]
- gi|17978821|gb|AAL47547.1| (AY065966) aminoglycoside acetyltransferase [Pseudomonas putida]
- gi|507311|gb|AAA25685.1|_1:165 (L25666) aminoglycoside 6'-N-acetyltransferase [Pseudomonas fluorescens]
- gi|1220458|gb|AAA91886.1| (L25617) aminoglycoside 6-N-acetyltransferase [Pseudomonas fluorescens]
- gi|6752462|gb|AAF27724.1|AF156486_3 (AF156486) aminoglycoside 6'-N-acetyltransferase type II AAC6'Ib [Klebsiella pneumoniae]
- gi|7715966|gb|AAF68221.1|AF202035_1 (AF202035) aminoglycoside 6'-N-acetyltransferase [Enterobacter cloacae]
- gi|8546575|emb|CAB94708.1| (AJ243491) aminoglycoside acetyl-transferase [Acinetobacter baumannii]
- gi|13508546|emb|CAC35171.1| (AJ278514) (6')-Ib' aminoglycoside acetyltransferase [Achromobacter xylosoxidans subsp. denitrificans]
- gi|14161937|gb|AAK13431.2|AF322577_3 (AF322577) aminoglycoside 6'-N-acetyltransferase [Klebsiella pneumoniae]
- gi|14164992|gb|AAK55331.1|AF371964_2 (AF371964) aminoglycoside 6'-N-acetyltransferase type 1b [Burkholderia cepacia]
- gi|14276842|gb|AAK58419.1|AF315351_3 (AF315351) acetyltransferase [Pseudomonas aeruginosa]
- gi|20530869|gb|AAM27274.1|AF418284_4_1:165 (AF418284) aminoglycoside 6'-acetyltransferase type I AACA4 [Pseudomonas aeruginosa]
- gi|15072886|emb|CAC48060.1|_113:321 (AJ315451) putative acetylase [Rhizobium leguminosarum bv. viciae]
- gi|18105477|gb|AAL59665.1|_138:331 (AF237701) putative acetylase [Pseudomonas fluorescens]
- gi|896284|gb|AAA69748.1|_1:158 (M21682) unknown protein [Plasmid pJHC-MW1]
- gi|402630|emb|CAA42873.1|_1:158 (X60321) 6'-N-aminoglycoside acetyltransferase [Pseudomonas aeruginosa]
- gi|19112687|ref|NP_595895.1|_117:328 (NC_003423) hypothetical protein [Schizosaccharomyces pombe]
- gi|7491437|pir||T39729 hypothetical protein SPBC17G9.06c - fission yeast (Schizosaccharomyces pombe)
- gi|5738527|emb|CAB52804.1| (AL109846) hypothetical protein [Schizosaccharomyces pombe]
- gi|3220159|gb|AAC23553.1|_1:158 (AF024602) AacA4 protein [Pseudomonas aeruginosa]
- gi|77607|pir||A37201_6:177 aminoglycoside N6'-acetyltransferase (EC 2.3.1.82) - Pseudomonas aeruginosa plasmid pSCH884
- gi|150961|gb|AAA25688.1| (M29695) 6'-N-acetyltransferase [Pseudomonas aeruginosa]
- gi|5670199|gb|AAD46626.1|AF162771_1_8:177 (AF162771) aminoglycoside 6'-N-acetyltransferase [Pseudomonas aeruginosa]
- gi|15608487|ref|NP_215863.1|_1:204 (NC_000962) hypothetical protein Rv1347c [Mycobacterium tuberculosis H37Rv]
- gi|15840802|ref|NP_335839.1| (NC_002755) acetyltransferase, putative [Mycobacterium tuberculosis CDC1551]
- gi|1723053|sp|Q11017|YD47_MYCTU Hypothetical protein Rv1347c
- gi|7476733|pir||B70740 hypothetical protein Rv1347c - Mycobacterium tuberculosis (strain H37RV)
- gi|1419050|emb|CAA99980.1| (Z75555) hypothetical protein Rv1347c [Mycobacterium tuberculosis H37Rv]
- gi|13880997|gb|AAK45653.1| (AE007011) acetyltransferase, putative [Mycobacterium tuberculosis CDC1551]
- gi|16263719|ref|NP_436512.1|_147:354 (NC_003037) putative siderophore biosynthesis protein [Sinorhizobium meliloti]
- gi|14524438|gb|AAK65924.1| (AE007312) putative siderophore biosynthesis protein [Sinorhizobium meliloti]
- gi|17227889|ref|NP_484437.1|_9:187 (NC_003272) hypothetical protein [Nostoc sp. PCC 7120]
- gi|17129738|dbj|BAB72351.1| (AP003582) ORF_ID:all0393~hypothetical protein [Nostoc sp. PCC 7120]
- gi|150951|gb|AAA25680.1|_4:171 (L06163) aminoglycoside 6'-N-acetyltransferase [Pseudomonas fluorescens]
- gi|16263714|ref|NP_436507.1|_11:190 (NC_003037) RhbD Rhizobactin siderophore biosynthesis protein [Sinorhizobium meliloti]
- gi|6685847|sp|Q9Z3Q9|RHBD_RHIME Rhizobactin siderophore biosynthesis protein rhbD
- gi|11281464|pir||T46817 rhbD protein [imported] - Rhizobium meliloti
- gi|4151934|gb|AAD09415.1| (AF110737) RhbD [Sinorhizobium meliloti]
- gi|14524432|gb|AAK65919.1| (AE007311) RhbD Rhizobactin siderophore biosynthesis protein [Sinorhizobium meliloti]
- gi|15615184|ref|NP_243487.1|_13:185 (NC_002570) BH2621~unknown conserved protein in others [Bacillus halodurans]
- gi|10175242|dbj|BAB06340.1| (AP001516) BH2621~unknown conserved protein in others [Bacillus halodurans]
- gi|16120152|ref|NP_395740.1|_13:193 (NC_002608) iron transport protein B; IucB [Halobacterium sp. NRC-1]
- gi|10584268|gb|AAG20875.1| (AE005155) iron transport protein B; IucB [Halobacterium sp. NRC-1]
- gi|16121804|ref|NP_405117.1|_16:184 (NC_003143) putative siderophore biosynthetic enzyme [Yersinia pestis]
- gi|15979574|emb|CAC90354.1| (AJ414149) putative siderophore biosynthetic enzyme [Yersinia pestis]
- gi|15823934|dbj|BAB69155.1|_7:175 (AB070936) alcB homolog (acetyltransferase homolog) [Streptomyces avermitilis]
- gi|21224146|ref|NP_629925.1|_22:225 (NC_003888) conserved hypothetical protein [Streptomyces coelicolor A3(2)]
- gi|7479553|pir||T35121 hypothetical protein SC4H2.22 SC4H2.22 - Streptomyces coelicolor
- gi|2995309|emb|CAA18337.1| (AL022268) conserved hypothetical protein [Streptomyces coelicolor A3(2)]
- gi|625926|pir||A36965_223:415 malonyl-CoA decarboxylase (EC 4.1.1.9) [validated] - Saccharopolyspora erythraea
- gi|484225|gb|AAA26500.1| (L05192) malonyl CoA decarboxylase [Saccharopolyspora erythraea]
- gi|545170|gb|AAC60466.1| (S68884) malonyl-coenzyme A decarboxylase [Saccharopolyspora erythraea]
- gi|11354237|pir||T44594_23:191 alcaligin synthesis protein alcB [validated] - Bordetella bronchiseptica
- gi|1778029|gb|AAB40619.1| (U61153) AlcB [Bordetella bronchiseptica]
- gi|21221235|ref|NP_627014.1|_12:178 (NC_003888) putative aceytltranferase [Streptomyces coelicolor A3(2)]
- gi|7544048|emb|CAB87221.1| (AL163641) putative aceytltranferase [Streptomyces coelicolor A3(2)]
- gi|17233031|ref|NP_490121.1|_2:162 (NC_003276) aminoglycoside N6'-acetyltransferase [Nostoc sp. PCC 7120]
- gi|17135553|dbj|BAB78099.1| (AP003600) aminoglycoside N6'-acetyltransferase [Nostoc sp. PCC 7120]
- gi|15963810|ref|NP_384163.1|_8:169 (NC_003047) HYPOTHETICAL ACETYLTRANSFERASE PROTEIN [Sinorhizobium meliloti]
- gi|15072985|emb|CAC41444.1| (AL591782) HYPOTHETICAL ACETYLTRANSFERASE PROTEIN [Sinorhizobium meliloti]
- gi|13474178|ref|NP_105746.1|_9:165 (NC_002678) aminoglycoside 6'-N-acetyltransferase [Mesorhizobium loti]
- gi|14024930|dbj|BAB51532.1| (AP003005) aminoglycoside 6'-N-acetyltransferase [Mesorhizobium loti]
- gi|16264741|ref|NP_437533.1|_1:165 (NC_003078) putative aminoglycoside 6'-N-acetyltransferase, similar to amikacin resistance protein [Sinorhizobium meliloti]
- gi|15140879|emb|CAC49393.1| (AL603645) putative aminoglycoside 6'-N-acetyltransferase, similar to amikacin resistance protein [Sinorhizobium meliloti]
- gi|21222453|ref|NP_628232.1|_20:202 (NC_003888) putative acetyltransferase [Streptomyces coelicolor A3(2)]
- gi|13122143|emb|CAC32321.1| (AL583944) putative acetyltransferase [Streptomyces coelicolor A3(2)]
- gi|125189|sp|P14510|KANR_AGRTU_10:101 KANAMYCIN RESISTANCE PROTEIN (KM-R)
- gi|77932|pir||A23957 kanamycin resistance protein - Agrobacterium tumefaciens plasmid pSA (fragment)
- gi|150817|gb|AAA25646.1| (M11444) kanamycin-resistance (Km-R) [Plasmid pSa]
- gi|224663|prf||1110196B_10:101 kanamycin resistance gene [Escherichia coli]
- gi|801877|dbj|BAA08931.1|_1:100 (D50438) aminoglycoside 6'-N-acetyltransferase [Serratia marcescens]
- gi|5532428|gb|AAD44721.1|AF139865_1_3:80 (AF139865) 6'-N-acetyltransferase AAC(6')-IbCP301 [synthetic construct]
- gi|15889364|ref|NP_355045.1|_20:156 (NC_003062) AGR_C_3768p [Agrobacterium tumefaciens] [Agrobacterium tumefaciens str. C58 (Cereon)]
- gi|17935965|ref|NP_532755.1| (NC_003304) acetyltransferase [Agrobacterium tumefaciens str. C58 (U. Washington)]
- gi|15157210|gb|AAK87830.1| (AE008124) AGR_C_3768p [Agrobacterium tumefaciens str. C58 (Cereon)]
- gi|17740539|gb|AAL43071.1| (AE009158) acetyltransferase [Agrobacterium tumefaciens str. C58 (U. Washington)]
- gi|5532440|gb|AAD44727.1|AF139871_1_1:59 (AF139871) 6'-N-acetyltransferase AAC(6')-IbSSF8 [synthetic construct]
- gi|5532436|gb|AAD44725.1|AF139869_1_2:55 (AF139869) 6'-N-acetyltransferase AAC(6')-IbCP262 [synthetic construct]
- gi|5532434|gb|AAD44724.1|AF139868_1_2:53 (AF139868) 6'-N-acetyltransferase AAC(6')-IbCP210 [synthetic construct]

              10        20        30        40        50             60
              |         |         |         |         |              |
   1 MTKPTSAGQADDALVRLARERFDLPDQVRRLARPPVPSLEPPYGLRVAQLT.....DAEMLAEWM
   2 ---------------------SRPKTKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
   3 ---------------------SRPKTKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
   4 ------------------------QRKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
   5 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
   6 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
   7 --------------------PVMSKTKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
   8 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
   9 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  10 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  11 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  12 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  13 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  14 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  15 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  16 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  17 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  18 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  19 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  20 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  21 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  22 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  23 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  24 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  25 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  26 --------DYGDDPAVALYTKLGVREDVMHFDIDPLTNSNDSVTLRLMTEH.....DLAMLYEWV
  27 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  28 -------------------------TKLGITKYSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  29 -PANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVs....DAERFTRWM
  30 -PANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVs....DAERFTRWM
  31 --------------------------------HSIVTNSNDSVTLRLMTEH.....DLAMLYEWL
  32 ---------------------------------SIVTNSTDSVTLRLMTEH.....DLAMLYEWL
  33 -------------------------------------NSNDSVTLRLMTEH.....DLAMLYEWL
  34 -PANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVs....DAERFTRWM
  35 -------------------------------------NSNDSVTLRLMTEH.....DLAMLYEWL
  36 -------------------------------------NSTDSVTLRLMTEH.....DLAMLYEWL
  37 -------------------------------------NSNDSVTLRLMTEH.....DLAMLYEWL
  38 -------------------------------------NSTDSVTLRLMTEH.....DLAMLYEWL
  39 ---NRTAGQMQYDTERHLWYPQRPPRPDGEVYRRFDPNIKRTLSFRLPEVDh....DAPQFTRWM
  40 -----------------------------------------------MTEH.....DLAMLYEWL
  41 -----------------------------------------------MTEH.....DLAMLYEWL
  42 -----------------------------------------------MTEH.....DLAMLYEWL
  43 -----------------------------------------------MTEH.....DLAMLYEWL
  44 -----------------------------------------------MTEH.....DLAMLYEWL
  45 -----------------------------------------------MTEH.....DLAMLYEWL
  46 --QLSYPLPPVQEMTAGRYHPRRPAKPKGTVYQRFIPWLEREIAFTVADAEt....DLAAFHRWM
  47 ----------------GKRHPLRAPKPCGEVYRRFDARLGAWISLRTLEIDv....DLARFNRWQ
  48 ---------------------------------------------------.....---MLYEWL
  49 ---------------------------------------------------.....---MLYEWL
  50 WMYTRCSDWPLSYLPNQVIRRPKCPKPGSTLYERFIPSLNETLSFVSLDIEq....HLQYFHEWQ
  51 ---------------------------------------------------.....---MLYEWL
  52 ----------------------------------------PPITLRLMTER.....DLPMLHDWL
  53 ------------------------------------------IVLRVMAEN.....DLPMLHAWL
  54 MTKPTSAGQADDALVRLARERFDLPDQVRRLARPPVPSLEPPYGLRVAQLT.....DAEMLAEWM
  55 -ASPSVTFPRRDHFDGRTEHPLRPPKPAGCVYARFIPWLSGTLSLHVATLN.....DLPDIHRWM
  56 ------------------------------SYARFDAAINKTIAFRPVVLEe....DLNLIHNWM
  57 ----------------------------------------GVVTLRPMTED.....DIGMLHEWL
  58 -----------------------------LAYSRYDPDIRRTISFRLLEKQr....DLKLLWRWM
  59 ----------------------------------FDHVVNKKLSFRHVTMD.....DVDMLHSWM
  60 ------------------------------AYRRPDPQIDRTVAFRRVALDr....DLGRLHAWL
  61 ---------------------------------------SGGFQLRPLVLAh....DVTWLTDWV
  62 ----------------------------------------GTFTVRPLDPTr....DAELLHGWV
  63 --ALFRSPAHDAAEAGTARAREDLLDGIADWGPSDTPA--GVFHLVPADLEr....DVPLIARWM
  64 ------------------DVPNPLHEGKSDVPPPPVPVLGGPWSLRPVEVAvh7gpDVALVHRWM
  65 ---------------------------------------GKGLALRSLDPEa....DAAQLQQWF
  66 -----------------------------------------ALTLRPVDPLt....DAVLLHGWL
  67 ------------------------------------------INLRPATLA.....DLNLLRHWD
  68 ------------------------------------------VSFEPVAEG.....HLPMLLAWL
  69 ------------------------------------------YDFRPVTEK.....DLPMIAGWL
  70 -----------------------------------------MIEFRSLTEA.....DFLMLCEWL
  71 --------------------------------------LDGFGTVRVLPLDpaa..DAAVVHGWV
  72 ---------------------------------------------------.....---------
  73 ---------------------------------------------------.....---------
  74 ---------------------------------------------------.....---MLYEWL
  75 ---------------------------------------------------.....---------
  76 -------------------------------------------ILRAARLD.....DAEALTELF
  77 ---------------------------------------------------.....---------
  78 ---------------------------------------------------.....---------
  79 ---------------------------------------------------.....---------


              70            80        90        100       110       120
              |             |         |          |         |         |
   1 NRPHLAAAWEYDWP....ASRWRQHLNAQLEGTY.SLPLIGSWHGTDGGYLELYWAAKDLISHYY
   2 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
   3 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
   4 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
   5 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
   6 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPCIAMLNGEPIGYAQSYVALGSGDGWWE
   7 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
   8 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
   9 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  10 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  11 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  12 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  13 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  14 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  15 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  16 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  17 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  18 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  19 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  20 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  21 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  22 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  23 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  24 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  25 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  26 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGGGDGWWE
  27 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  28 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  29 NDPRVEYFWEQSGS....LEVQTAYLERQLTGKH.AFPLIGCFDDRPFSYFEIYWAAEDRIGRHY
  30 NDPRVEYFWEQSGS....LEVQTAYLERQLTGKH.AFPLIGCFDDRPFSYFEIYWAAEDRIGRHY
  31 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  32 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  33 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  34 NDPRVEYFWEQSGS....LEVQIAYLERQLTSKH.AFPLIGCFDDRPVSNIEIYWAAEDRIGRHY
  35 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  36 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  37 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  38 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  39 NSPRVDAFWEMSGP....LDVQAAYLQRQLDSPY.CYPLLGCFDDQPFGYFEVYWAAEDRIGRHY
  40 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  41 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  42 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  43 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  44 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  45 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  46 NDEQVNTIWEDAGS....IGKHREILEERIADPH.VLPLIGSFADIPFGYFEVYWAKENRLGPFY
  47 NSARVANFWQESGS....LEQHRDYLQKLAADPH.TLTLIGCIDDEPFAYFEAYWAKEDRIAPFY
  48 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  49 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  50 NKPRVEYFWNESGS....WDQHHEYLTTLQNDPH.SFGVIGCFNDVPFAYFEVYWVPEDRIAPFA
  51 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  52 NRPHIVEWWGGDEErptlDEVLEHYLPRAMAEES.VTPYIAMLGEEPIGYAQSYVALGSGDGWWE
  53 NRPHIVEWWGGEDErptlDEVLEHYSPEVLAKQA.VVPYIAMLDDEPIGYAQSYIALGSGDGWWE
  54 NRPHLAAAWEYDWP....ASRWRQHLNAQLEGTY.SLPLIGSWHGTDGGYLELYWAAKDLISHYY
  55 NNPRVNEFWNEAGS....KAAHGRYLERMFADPH.TIPLIGRFNARAFSYFEIYWAKEDVIGPFS
  56 NQPHVIPFWNLAFD....LERMREHLQRTLADKH.QTLYIGCLDDEPMSYWESYWTIDDIVARHY
  57 NRPHIVEWWGGERPsl..EEVKEDYRPSALAEEG.VTPYIGLLDGTPFAFAQSYVALGSGGGWWE
  58 NQAHVVPQWKMAKP....IEDIAAYIDINLADPH.QDPYIGLIDGTPMSYWEAYWAKDDVLGRYY
  59 HEEHVIPYWKLNIP....LVDYKKHLQTFLNDDH.QTLMVGAINGVPMSYWESYWVKEDIIANYY
  60 TSDHVTPYWSLGAP....LPAFHQAIGDHLEDDH.VTAYVGCIDGVPMSYVERYWVAADPLADHY
  61 NREYAHYWGMQGYS....PQQVKAFYQELNTSQP.GGVFVGVYQQQPAFLLERYLAQHDVIADYY
  62 THPKSAFWMMQEAR....LHDVEREYMAIAASEY.HDAFLGLLDDEPVFLMEKYDPAHVELVGLY
  63 NDPAVAAYWELTGP....QSVTADHLRAQLAGDGrSVPCVGTLDGVPMSYWEIYRADLDPLARYC
  64 NTPHVAHHWNQAWP....LERWREELAHQLGGEH.SLPCVVGHEGREVAYLELYRVTRDKLAGCY
  65 SMDYARFWSMQDSS....VHQVRDFYTALCSSGH.AGAWLGLHHGRAAFLVECYDPARDQVGEHY
  66 THPKSAFWMMQDAR....LVDVERAYMELAADEH.QQAHLGLHDGVPAFLTERYDPAHRELVGLY
  67 EQPHVIA----SDP....NDDWGWEVELARSPDW.REQLIVEIDSRPIGFIQIIDPAQEDSHYWG
  68 SEPHVRQWWGDP--....-DVELGLIRDGCAKGE.VDGFVFRVKGEPAGYIQSWVPSEYDEEPWA
  69 AEPEVAEWWNDPDTe...IAEIRDHIDSI----S.VEPLIVELDGKPIAYLQSYDPHLEDDHPYA
  70 NSPHMRAHYQKTPIti..EEVQGKYSERLSPSHP.THCHIARYNGETFGMLQCYSLRNYPDFASE
  71 GEERAAFWGMNDLT....RDQVAAVYAHMDTLDT.HHAFLVVKDGEPAALLQTYDPAADRVSECY
  72 --------------....----------------.--------------------------RWWE
  73 --------------....----------------.--------------------------RWWE
  74 NRSHIVEWWGGEEArptlADVQEQYLPSVLAQES.VTPYIAMLNGEPIGYAQSYVALGSGDGWWE
  75 --------------....----------------.-----------------------------E
  76 NLPGVRYGTLRQPF....QSVEKTRKAMENRGPN.DIAIIGEWHGKIVANGGLYRRAGRQAH---
  77 --------------....----------------.------------------------------
  78 --------------....----------------.------------------------------
  79 --------------....----------------.------------------------------


              130       140         150       160       170       180  
               |         |           |         |         |         |  
   1 D.ADPYDLGLHAAIADLSKVN..RGFGPLLLPRIVASVFANEPRCRRIMFDPDHRNTATRRLCEW
   2 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
   3 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
   4 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
   5 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
   6 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
   7 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
   8 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPANLRAIRCYEK
   9 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  10 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPAPSNLRAIRCYEK
  11 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNARAIRCYEK
  12 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLAAIRCYEK
  13 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSASNLRAIRCYEK
  14 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEA
  15 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIACYEK
  16 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  17 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYAK
  18 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  19 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRAYEK
  20 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCAEK
  21 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  22 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAARCYEK
  23 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSALRAIRCYEK
  24 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  25 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  26 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  27 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDASPSNLRAIRCYEK
  28 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  29 S.WQPFDRGLHLLVGEQQWRG..AHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEP
  30 S.WQPFDRGLHLLVGEQQWRG..AHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEP
  31 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  32 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  33 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  34 S.WQPFDRGLHLLVGEQQWRG..AHYVQSWLRGVTHYLLLNEPRTQRTVLEPRTDNQRLFRHLEP
  35 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  36 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  37 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVARIQTDPSPSNLRAIRCYEK
  38 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  39 R.WQPFDRGLHMLVGEENWRG..AQYIHSWLRGLTHYLYLDESRTTRVVAEPRIDNQRLFHHLPA
  40 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  41 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  42 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  43 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  44 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  45 EeTDPGVRGIDQSLANASQLG..KSLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  46 D.ADDYDRGWHVAIGEPDYRG..KKWISAWLPSLMHFIFLDDPRTKRIVGEPRASHEQQIRNLDR
  47 E.VDDYDRGIHMLVGEEHHRG..PHKVASWLSALVHYLFLDDPRTQRVVAEPRADNARMIGHMHN
  48 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  49 EeTDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  50 QpWHTHDRGFHALVGNDKFRG..PHRVPVWLSSITHMLFLDDPRTQRVLLEPRIDNSKFINYLIE
  51 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  52 DeTDPGVRGIDQSLADPTQLN..KGLGTRLVRALVELLF-SDPTVTKIQTDPTPNNHRAIRCYEK
  53 DeTDPGVRGIDQSLANPSQLN..KGLGTKLVRSLVELLF-SDPAVTKIQTDPSPSNHRAIRCYEK
  54 D.ADPYDLGLHAAIADLSKVN..RGFGPLLLPRIVASVFANEPRCRRIMFDPDHRNTATRRLCEW
  55 G.AGDYDRGCHVIVGEESCRG..KPWFTAWLPSLLHLMFLDDPRTERIVQEPSAAHHRQLGNLQR
  56 S.AEATDQGIHLLIGETKFLG..KGYALPLLRAMVFFQF-ENTATQKIIAEPDIRNQKMIHVFEK
  57 EeTDPGVRGIDQSIADSGLLG..RGYGTRLVQALVDLLF-ADPQVSKVQTDPSPNNMRAIRCYEK
  58 P.AEKKDRGWHMLVGEPSFFG..RGIAPAVIRAFTRFLFLDDPGTQKVVGEPSVAARRLLRYAPA
  59 P.FEEHDQGIHLLIGPQEYLG..QGLIYPLLLAIMQQKF-QEPDTNTIVAEPDRRNKKMIHVFKK
  60 D.ADDNDQGIHILIGPPEYLG..QGCGTALLRAMTALAF-RHAATDRVVAEPDATNDAAIAAFER
  61 P.AQPDDVGMHILVAPPVERI..TGFTWRVFQAIMTFIF-SDPTVARIVVEPDVRNEKIHRLNKR
  62 E.PEPGDVGMHFLVAPTDTPV..HGFTRAVITAVMEHLF-ADPATRRVVVEPDVGNKAVHALNEA
  63 P.VRPHDTGVHLLIGDGAHRG..RGLGTELIRAVVDLVLAGRPACTRVLAEPDVRNRQSVAAFLG
  64 P.YGPHDLGVHIAIGEREVLG..RGFGSSLLRAVAGALLDADPRCARVVAEPNVHNEASVRAFAK
  65 C.VRPGDLGMHLLIAPPTEHI..PGFSRAVFALVMRFMF-DRLHAARVVVEPDVNNTKIHALNLS
  66 E.PEPGDVGMHFLVAPTDRPV..HGFTRAVITTVMTELF-ADPATRRVVVEPDVTNTAVHALNAA
  67 D.VGENLRAIDIWIGEETDLG..KGYGTQMMRLALARCF-ADPLVTAILVDPLASNTRVHRFYER
  68 KdLSGDTPGVDIFIGPPEMTG..KGVAAMALRAFAARLF--ESGAARIVIDPDAGNRRAVRAYAK
  69 D.QPFGTLGIDLSIGRPELLG..IGHGSAIVRQFVEDLF--REGVPRVIIDPDPANLRAIRAYEK
  70 I.GEQDGVAVDLFIGEERFIG..KDFGKAMLRSYVLNVV-PSIFPQECFICHAKENKIAIRGSLS
  71 A.AEPGDIGVHLLLAPAGAEGtrPGWTAALSGALMAYVL-LGLDRTRIVVDPDVANEKAIARFLK
  72 EeTDPGVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  73 EeTDPEVRGIDQSLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  74 EeTDPGVRGIDQSLANASQLG..KGLGTKLVR---------------------------------
  75 E.TDPGVRGIDQLLANASQLG..KGLGTKLVRALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  76 -.IADLVISVH-----DDFAG..KGVGSHLLGALIDTAD-NWHDIRRIELNVFTDNLPAIRLYEK
  77 -.-------------------..--------RALVELLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  78 -.-------------------..-------------LLF-NDPEVTKIQTDPSPSNLRAIRCYEK
  79 -.-------------------..---------------F-NDPEVTKIQTDPSPSNLRAIRCYEK


                190         200       210
                 |           |         |
   1 AGC.....KFLGEHDTTN..RRMALYALEAPTTAA
   2 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
   3 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
   4 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
   5 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
   6 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
   7 AGF.....EKQGTVTTPD..GPAVYMVQTRQAF--
   8 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
   9 AGF.....EAQGTVTTPD..GPAVYMVQTRQAF--
  10 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  11 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  12 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  13 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  14 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  15 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  16 AGF.....ARQGTVTTPD..GPAVYMVQTRQAF--
  17 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  18 AGF.....ERAGTVTTPD..GPAVYMVQTRQAF--
  19 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  20 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  21 AGF.....ERQATVTTPD..GPAVYMVQTRQAF--
  22 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  23 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  24 AGL.....ERQGTVTTPD..GPAVYMVQTRQAF--
  25 AAF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  26 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  27 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  28 AGA.....ERQGTVTTPD..GPAVYMVQTRQAF--
  29 AGY.....RTIKEFDFPH..KRSRMVMADRHHFF-
  30 AGY.....RTIKEFDFPH..KRSRMVMADRHHFF-
  31 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  32 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  33 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  34 AGY.....RTIKEFDFPH..KRSRMVMADRHHFF-
  35 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  36 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  37 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  38 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  39 AGY.....HTLKEFDFPH..KRSRLIMNQRADFF-
  40 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  41 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  42 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  43 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  44 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  45 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  46 SGF.....AKVKHFDFPH..KRALLVMLGRERFFG
  47 QCF.....HCEKEFDFPH..KRAALMILGRERFF-
  48 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  49 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  50 ENY.....SKRLEFNFPH..KRAAFMEITRNMFFS
  51 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  52 AGF.....VREKIITTPD..GPAVYMVQTRQAF--
  53 AGF.....VQEKNILTPD..GPAVYMVQTRQAF--
  54 AGC.....KFLGEHDTTN..RRMALYALE------
  55 SGF.....SHTRTVDLPT..KRAAIMSISRQRFF-
  56 CGF.....EFQKEIELPD..KFGALMFCDRQLFF-
  57 AGF.....RKVKVVSTPD..GPAMYMLHERP----
  58 CAF.....EEQGEIDLPD..KRAKLMFCYRERF--
  59 CGF.....QPVKEVELPD..KIGLLMKCEQNVF--
  60 AGF.....EPRETFRFPHedKDATRVVCDRERFV-
  61 AGF.....VYQQQLTLPH..KTAWLAFCTREQY--
  62 VGF.....VPEREIQKPE..KKALLSFCTREQFA-
  63 AGF.....RPTGEVDLPT..KRAVLMIRARE----
  64 AGF.....VREREIGLPA..KNSALMVFS------
  65 MGF.....VYAGLARFRE..KTASLAFCTRAQF--
  66 VGF.....VPEREIQKPE..KKALLSFCTREQF--
  67 LGF.....KFIEHRCFGD..DECFVYRLNREDW--
  68 AGF.....VPFGEWIDES..GRTHLMELKRTEF--
  69 AGF.....RAIDRRQSVY..GDVVLMAID------
  70 AGF.....LPYRDVIERG..VESLLLSFDR-----
  71 QGFt10peVDLPDVYLPE..KKAQLAFLRREV---
  72 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  73 AGF.....ERQGTVTTPD..GPAVYMVQTRQAF--
  74 ---.....----------..---------------
  75 AGW.....ERQGTVTTPD..GPA------------
  76 FGF.....EREGT-----..---------------
  77 AGK.....ERQGTVTTPD..GPAVYMVQTRQAF--
  78 AGS.....ERQGTVTTPD..GPAVYMVQTRQAF--
  79 AGG.....ERQGTVTTPD..GPAVYMVQTRQAF--