PFRMAT SS TARGET T0152 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0152.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0152.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0152.t2k.str.rdb (weight 1.53983) METHOD T0152.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0152.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0152 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0152.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 28 METHOD METHOD ============================================ METHOD Comments from T0152.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0152 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0152.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 28 METHOD METHOD ============================================ METHOD Comments from T0152.t2k.str.rdb METHOD ============================================ METHOD TARGET T0152 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0152.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 28 METHOD METHOD ============================================ METHOD Comments from T0152.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0152 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0152.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 28 METHOD METHOD ============================================ MODEL 1 M C 0.91 T C 0.78 K C 0.75 P C 0.72 T C 0.71 S C 0.71 A C 0.75 G C 0.71 Q C 0.63 A C 0.49 D H 0.55 D H 0.55 A H 0.57 L H 0.56 V H 0.60 R H 0.48 L C 0.51 A C 0.54 R C 0.54 E C 0.70 R C 0.80 F C 0.82 D C 0.85 L C 0.90 P C 0.87 D C 0.85 Q C 0.80 V C 0.72 R C 0.66 R C 0.62 L C 0.61 A C 0.71 R C 0.77 P C 0.79 P C 0.74 V C 0.79 P C 0.69 S C 0.69 L C 0.69 E C 0.80 P C 0.82 P C 0.65 Y E 0.70 G E 0.80 L E 0.84 R E 0.75 V E 0.70 A C 0.62 Q C 0.81 L H 0.65 T H 0.70 D H 0.72 A H 0.91 E H 0.92 M H 0.93 L H 0.95 A H 0.95 E H 0.92 W H 0.87 M H 0.73 N H 0.52 R C 0.72 P H 0.65 H H 0.67 L H 0.81 A H 0.84 A H 0.84 A H 0.79 W H 0.66 E H 0.48 Y C 0.64 D C 0.76 W C 0.83 P C 0.79 A H 0.80 S H 0.89 R H 0.91 W H 0.93 R H 0.93 Q H 0.93 H H 0.93 L H 0.93 N H 0.92 A H 0.91 Q H 0.86 L H 0.70 E C 0.57 G C 0.87 T C 0.86 Y C 0.85 S C 0.74 L C 0.54 P E 0.67 L E 0.85 I E 0.89 G E 0.90 S E 0.88 W E 0.76 H C 0.87 G C 0.91 T E 0.51 D E 0.76 G E 0.79 G E 0.86 Y E 0.89 L E 0.89 E E 0.89 L E 0.86 Y E 0.74 W E 0.53 A C 0.57 A C 0.59 K C 0.62 D C 0.72 L C 0.66 I C 0.65 S C 0.63 H C 0.62 Y C 0.60 Y C 0.66 D C 0.71 A C 0.81 D C 0.89 P C 0.85 Y C 0.88 D C 0.77 L C 0.50 G E 0.66 L E 0.77 H E 0.77 A E 0.80 A E 0.78 I E 0.66 A C 0.53 D C 0.76 L C 0.51 S H 0.52 K H 0.48 V C 0.71 N C 0.81 R C 0.67 G C 0.58 F H 0.62 G H 0.82 P H 0.93 L H 0.95 L H 0.95 L H 0.96 P H 0.96 R H 0.96 I H 0.96 V H 0.95 A H 0.95 S H 0.93 V H 0.89 F H 0.74 A C 0.57 N C 0.81 E C 0.88 P C 0.79 R C 0.77 C C 0.60 R E 0.55 R E 0.83 I E 0.87 M E 0.83 F E 0.68 D C 0.66 P C 0.83 D C 0.85 H C 0.63 R C 0.56 N H 0.67 T H 0.90 A H 0.94 T H 0.94 R H 0.95 R H 0.94 L H 0.93 C H 0.89 E H 0.83 W H 0.70 A C 0.61 G C 0.90 C C 0.77 K C 0.51 F E 0.52 L C 0.47 G C 0.48 E E 0.51 H E 0.54 D C 0.53 T C 0.78 T C 0.85 N C 0.87 R C 0.75 R C 0.55 M E 0.56 A E 0.73 L E 0.80 Y E 0.77 A E 0.76 L E 0.59 E C 0.48 A C 0.49 P C 0.44 T H 0.44 T C 0.54 A C 0.69 A C 0.92 END