PFRMAT SS TARGET T0150 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0150.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0150.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0150.t2k.str.rdb (weight 1.53983) METHOD T0150.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0150.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0150 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0150.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 77 METHOD METHOD ============================================ METHOD Comments from T0150.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0150 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0150.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 77 METHOD METHOD ============================================ METHOD Comments from T0150.t2k.str.rdb METHOD ============================================ METHOD TARGET T0150 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0150.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 77 METHOD METHOD ============================================ METHOD Comments from T0150.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0150 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0150.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 77 METHOD METHOD ============================================ MODEL 1 G C 0.76 S H 0.57 V H 0.78 D H 0.81 F H 0.91 A H 0.94 F H 0.95 E H 0.96 L H 0.96 R H 0.95 K H 0.95 A H 0.95 Q H 0.93 D H 0.86 T C 0.54 G C 0.92 K C 0.84 I E 0.53 V E 0.54 M C 0.50 G C 0.61 A H 0.73 R H 0.90 K H 0.93 S H 0.94 I H 0.95 Q H 0.96 Y H 0.96 A H 0.95 K H 0.91 M C 0.59 G C 0.91 G C 0.90 A C 0.75 K E 0.56 L E 0.92 I E 0.93 I E 0.93 V E 0.88 A E 0.57 R C 0.73 N C 0.82 A C 0.88 R C 0.89 P H 0.64 D H 0.69 I H 0.79 K H 0.84 E H 0.82 D H 0.80 I H 0.91 E H 0.95 Y H 0.95 Y H 0.95 A H 0.95 R H 0.94 L H 0.86 S C 0.58 G C 0.93 I C 0.89 P C 0.64 V E 0.86 Y E 0.91 E E 0.91 F E 0.87 E E 0.57 G C 0.78 T C 0.83 S H 0.72 V H 0.82 E H 0.80 L H 0.85 G H 0.81 T H 0.81 L H 0.73 L C 0.55 G C 0.91 R C 0.86 P C 0.77 H C 0.63 T E 0.56 V E 0.85 S E 0.91 A E 0.93 L E 0.92 A E 0.91 V E 0.87 V E 0.71 D C 0.70 P C 0.80 G C 0.80 E H 0.59 S H 0.80 R H 0.85 I H 0.86 L H 0.84 A H 0.77 L H 0.70 G H 0.48 G C 0.58 K C 0.70 E C 0.91 END