PFRMAT SS TARGET T0148 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0148.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0148.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0148.t2k.str.rdb (weight 1.53983) METHOD T0148.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0148.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0148 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0148.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 17 METHOD METHOD ============================================ METHOD Comments from T0148.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0148 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0148.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 17 METHOD METHOD ============================================ METHOD Comments from T0148.t2k.str.rdb METHOD ============================================ METHOD TARGET T0148 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0148.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 17 METHOD METHOD ============================================ METHOD Comments from T0148.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0148 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0148.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 17 METHOD METHOD ============================================ MODEL 1 M C 0.91 P C 0.86 S C 0.75 F C 0.65 D C 0.58 I C 0.45 V C 0.47 S C 0.51 E C 0.61 I C 0.78 T C 0.80 L H 0.87 H H 0.93 E H 0.94 V H 0.95 R H 0.94 N H 0.94 A H 0.93 V H 0.95 E H 0.94 N H 0.94 A H 0.94 N H 0.90 R H 0.86 V H 0.77 L H 0.65 S H 0.48 T C 0.57 R C 0.54 Y C 0.52 D C 0.59 F C 0.70 R C 0.83 G C 0.89 V C 0.71 E E 0.52 A E 0.75 V E 0.87 I E 0.89 E E 0.90 L E 0.79 N C 0.60 E C 0.81 K C 0.86 N C 0.81 E E 0.56 T E 0.88 I E 0.91 K E 0.90 I E 0.87 T E 0.74 T C 0.56 E C 0.79 S C 0.78 D H 0.60 F H 0.70 Q H 0.76 L H 0.90 E H 0.91 Q H 0.92 L H 0.94 I H 0.95 E H 0.95 I H 0.95 L H 0.94 I H 0.94 G H 0.94 S H 0.94 C H 0.93 I H 0.92 K H 0.86 R C 0.55 G C 0.91 I C 0.89 E C 0.84 H H 0.60 S H 0.64 S H 0.62 L C 0.40 D C 0.54 I C 0.65 P C 0.72 A C 0.63 E C 0.53 S C 0.49 E C 0.50 H C 0.57 H C 0.74 G C 0.83 K C 0.74 L E 0.59 Y E 0.77 S E 0.83 K E 0.85 E E 0.86 I E 0.83 K E 0.84 L E 0.74 K E 0.45 Q C 0.63 G C 0.76 I C 0.69 E C 0.72 T H 0.85 E H 0.89 M H 0.92 A H 0.94 K H 0.94 K H 0.94 I H 0.95 T H 0.95 K H 0.95 L H 0.94 V H 0.90 K H 0.85 D H 0.71 S H 0.51 K C 0.85 I C 0.79 K C 0.52 V E 0.64 Q E 0.68 T E 0.72 Q E 0.71 I E 0.59 Q C 0.61 G C 0.82 E C 0.64 Q E 0.75 V E 0.84 R E 0.84 V E 0.76 T C 0.49 G C 0.72 K C 0.75 S C 0.71 R H 0.75 D H 0.84 D H 0.87 L H 0.95 Q H 0.96 A H 0.96 V H 0.96 I H 0.96 Q H 0.95 L H 0.92 V H 0.82 K H 0.61 S H 0.56 A C 0.54 E C 0.63 L C 0.75 G C 0.86 Q C 0.87 P C 0.77 F C 0.49 Q E 0.54 F E 0.56 N E 0.45 N C 0.51 F C 0.60 R C 0.75 D C 0.91 END