a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0147_twice ycdX, E.coli
- gi|16760159|ref|NP_455776.1|_12:288 (NC_003198) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
- gi|16502453|emb|CAD08410.1| (AL627269) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
- gi|16765065|ref|NP_460680.1|_12:288 (NC_003197) trpR controlled transcriptional unit in the 5' upstream region of the trp operon [Salmonella typhimurium LT2]
- gi|20141852|sp|O54453|TRPH_SALTY Protein trpH
- gi|16420251|gb|AAL20639.1| (AE008776) trpR controlled transcriptional unit in the 5' upstream region of the trp operon [Salmonella typhimurium LT2]
- gi|16129227|ref|NP_415782.1|_8:284 (NC_000913) putative enzymes [Escherichia coli K12]
- gi|3025078|sp|P77766|TRPH_ECOLI Protein trpH
- gi|7449461|pir||E64874 probable metal-dependent phosphoesterase yciV - Escherichia coli
- gi|1742058|dbj|BAA14800.1| (D90764) ORF_ID:o253#3; similar to [SwissProt Accession Number P44176] [Escherichia coli]
- gi|1742074|dbj|BAA14815.1| (D90765) ORF_ID:o253#3; similar to [SwissProt Accession Number P44176] [Escherichia coli]
- gi|1787520|gb|AAC74348.1| (AE000224) putative enzymes [Escherichia coli K12]
- gi|15801913|ref|NP_287933.1|_8:284 (NC_002655) putative enzymes [Escherichia coli O157:H7 EDL933]
- gi|15831092|ref|NP_309865.1| (NC_002695) putative enzymes [Escherichia coli O157:H7]
- gi|12515531|gb|AAG56549.1|AE005380_8 (AE005380) putative enzymes [Escherichia coli O157:H7 EDL933]
- gi|13361303|dbj|BAB35261.1| (AP002556) putative enzymes [Escherichia coli O157:H7]
- gi|16128997|ref|NP_415552.1|_1:245 (NC_000913) orf, hypothetical protein [Escherichia coli K12]
- gi|2495593|sp|P75914|YCDX_ECOLI Hypothetical protein ycdX precursor
- gi|7467104|pir||G64845 ycdX protein - Escherichia coli
- gi|1787271|gb|AAC74118.1| (AE000205) orf, hypothetical protein [Escherichia coli K12]
- gi|4062598|dbj|BAA35815.1| (D90740) ORF_ID:o231#2 [Escherichia coli]
- gi|4062607|dbj|BAA35824.1| (D90741) ORF_ID:o231#2 [Escherichia coli]
- gi|15801151|ref|NP_287168.1|_1:245 (NC_002655) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
- gi|15830665|ref|NP_309438.1| (NC_002695) hypothetical protein [Escherichia coli O157:H7]
- gi|12514563|gb|AAG55780.1|AE005314_8 (AE005314) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
- gi|13360871|dbj|BAB34834.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]
- gi|16122439|ref|NP_405752.1|_14:292 (NC_003143) conserved hypothetical protein [Yersinia pestis]
- gi|15980211|emb|CAC91017.1| (AJ414151) conserved hypothetical protein [Yersinia pestis]
- gi|16760013|ref|NP_455630.1|_1:245 (NC_003198) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
- gi|16764492|ref|NP_460107.1| (NC_003197) putative Histidinol phosphatase and related hydrolases of the PHP family [Salmonella typhimurium LT2]
- gi|16419651|gb|AAL20066.1| (AE008749) putative Histidinol phosphatase and related hydrolases of the PHP family [Salmonella typhimurium LT2]
- gi|16502307|emb|CAD08260.1| (AL627269) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
- gi|15641190|ref|NP_230822.1|_1:286 (NC_002505) conserved hypothetical protein [Vibrio cholerae]
- gi|11279907|pir||D82233 conserved hypothetical protein VC1177 [imported] - Vibrio cholerae (group O1 strain N16961)
- gi|9655653|gb|AAF94336.1| (AE004197) conserved hypothetical protein [Vibrio cholerae]
- gi|16122276|ref|NP_405589.1|_1:245 (NC_003143) conserved hypothetical protein [Yersinia pestis]
- gi|15980048|emb|CAC90849.1| (AJ414151) conserved hypothetical protein [Yersinia pestis]
- gi|2735355|gb|AAB93886.1|_3:250 (U92714) TrpH [Salmonella typhimurium]
- gi|15602481|ref|NP_245553.1|_3:272 (NC_002663) unknown [Pasteurella multocida]
- gi|12720889|gb|AAK02700.1| (AE006098) unknown [Pasteurella multocida]
- gi|17545859|ref|NP_519261.1|_9:284 (NC_003295) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
- gi|17428153|emb|CAD14842.1| (AL646062) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
- gi|20807816|ref|NP_622987.1|_25:304 (NC_003869) predicted metal-dependent phosphoesterases (PHP family) [Thermoanaerobacter tengcongensis]
- gi|20516375|gb|AAM24591.1| (AE013096) predicted metal-dependent phosphoesterases (PHP family) [Thermoanaerobacter tengcongensis]
- gi|15677660|ref|NP_274821.1|_2:274 (NC_003112) conserved hypothetical protein [Neisseria meningitidis MC58]
- gi|11279909|pir||A81040 conserved hypothetical protein NMB1824 [imported] - Neisseria meningitidis (group B strain MD58)
- gi|7227077|gb|AAF42159.1| (AE002531) conserved hypothetical protein [Neisseria meningitidis MC58]
- gi|15793623|ref|NP_283445.1|_2:273 (NC_003116) hypothetical protein NMA0635 [Neisseria meningitidis Z2491]
- gi|11279908|pir||E81983 hypothetical protein NMA0635 [imported] - Neisseria meningitidis (group A strain Z2491)
- gi|7379368|emb|CAB83925.1| (AL162753) hypothetical protein NMA0635 [Neisseria meningitidis Z2491]
- gi|2499170|sp|Q44408|YOR4_ANATH_9:240 Hypothetical 27.7 kDa protein in XYNA-ALFA intergenic region (ORF4)
- gi|1208897|emb|CAA93629.1| (Z69782) hypothetical protein [Anaerocellum thermophilum]
- gi|15601648|ref|NP_233279.1|_3:241 (NC_002506) conserved hypothetical protein [Vibrio cholerae]
- gi|11354819|pir||G82403 conserved hypothetical protein VCA0894 [imported] - Vibrio cholerae (group O1 strain N16961)
- gi|9658328|gb|AAF96791.1| (AE004417) conserved hypothetical protein [Vibrio cholerae]
- gi|20808367|ref|NP_623538.1|_8:240 (NC_003869) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
- gi|20516977|gb|AAM25142.1| (AE013147) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
- gi|16800263|ref|NP_470531.1|_334:557 (NC_003212) similar to DNA polymerase beta, to B. subtilis YshC protein [Listeria innocua]
- gi|16413653|emb|CAC96425.1| (AL596167) similar to DNA polymerase beta, to B. subtilis YshC protein [Listeria innocua]
- gi|15893800|ref|NP_347149.1|_2:236 (NC_003030) PHP family protein [Clostridium acetobutylicum]
- gi|15023371|gb|AAK78489.1|AE007565_8 (AE007565) PHP family protein [Clostridium acetobutylicum]
- gi|15598396|ref|NP_251890.1|_1:278 (NC_002516) conserved hypothetical protein [Pseudomonas aeruginosa]
- gi|11347987|pir||C83244 conserved hypothetical protein PA3200 [imported] - Pseudomonas aeruginosa (strain PAO1)
- gi|9949320|gb|AAG06588.1|AE004744_3 (AE004744) conserved hypothetical protein [Pseudomonas aeruginosa]
- gi|15615669|ref|NP_243973.1|_333:567 (NC_002570) DNA-dependent DNA polymerase beta chain [Bacillus halodurans]
- gi|10175729|dbj|BAB06826.1| (AP001517) DNA-dependent DNA polymerase beta chain [Bacillus halodurans]
- gi|16803271|ref|NP_464756.1|_334:557 (NC_003210) similar to DNA polymerase beta, to B. subtilis YshC protein [Listeria monocytogenes EGD-e]
- gi|16410647|emb|CAC99309.1| (AL591978) similar to DNA polymerase beta, to B. subtilis YshC protein [Listeria monocytogenes]
- gi|21402596|ref|NP_658581.1|_335:568 (NC_003995) POLXc, DNA polymerase X family [Bacillus anthracis A2012] [Bacillus anthracis str. A2012]
- gi|20808870|ref|NP_624041.1|_334:558 (NC_003869) DNA polymerase IV (family X) [Thermoanaerobacter tengcongensis]
- gi|20517526|gb|AAM25645.1| (AE013193) DNA polymerase IV (family X) [Thermoanaerobacter tengcongensis]
- gi|15924133|ref|NP_371667.1|_331:556 (NC_002758) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus Mu50]
- gi|15926727|ref|NP_374260.1| (NC_002745) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus N315]
- gi|13700943|dbj|BAB42239.1| (AP003132) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus N315]
- gi|14246913|dbj|BAB57305.1| (AP003361) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus Mu50]
- gi|16079911|ref|NP_390737.1|_333:556 (NC_000964) similar to DNA polymerase beta [Bacillus subtilis]
- gi|7430180|pir||C69985 probable DNA-dependent DNA polymerase beta chain yshC - Bacillus subtilis
- gi|1770035|emb|CAA99568.1| (Z75208) hypothetical protein [Bacillus subtilis]
- gi|2635324|emb|CAB14819.1| (Z99118) similar to DNA polymerase beta [Bacillus subtilis]
- gi|21282755|ref|NP_645843.1|_331:555 (NC_003923) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus MW2]
- gi|21204193|dbj|BAB94891.1| (AP004825) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus MW2]
- gi|21227996|ref|NP_633918.1|_347:571 (NC_003901) DNA polymerase beta [Methanosarcina mazei Goe1]
- gi|20906424|gb|AAM31590.1| (AE013426) DNA polymerase beta [Methanosarcina mazei Goe1]
- gi|15614846|ref|NP_243149.1|_6:256 (NC_002570) BH2283~unknown conserved protein [Bacillus halodurans]
- gi|10174903|dbj|BAB06002.1| (AP001515) BH2283~unknown conserved protein [Bacillus halodurans]
- gi|15610992|ref|NP_218373.1|_95:324 (NC_000962) hypothetical protein Rv3856c [Mycobacterium tuberculosis H37Rv]
- gi|15843487|ref|NP_338524.1| (NC_002755) conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
- gi|7477795|pir||E70655 hypothetical protein Rv3856c - Mycobacterium tuberculosis (strain H37RV)
- gi|1781100|emb|CAB06234.1| (Z83864) hypothetical protein Rv3856c [Mycobacterium tuberculosis H37Rv]
- gi|13883860|gb|AAK48338.1| (AE007189) conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
- gi|21219312|ref|NP_625091.1|_125:351 (NC_003888) conserved hypothetical protein [Streptomyces coelicolor A3(2)]
- gi|11071281|emb|CAC14354.1| (AL445945) conserved hypothetical protein [Streptomyces coelicolor A3(2)]
- gi|15606601|ref|NP_213981.1|_341:562 (NC_000918) DNA polymerase beta family [Aquifex aeolicus]
- gi|7430181|pir||F70423 DNA polymerase beta family - Aquifex aeolicus
- gi|2983818|gb|AAC07374.1| (AE000739) DNA polymerase beta family [Aquifex aeolicus]
- gi|20089612|ref|NP_615687.1|_351:575 (NC_003552) DNA-directed DNA polymerase, family X [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|19914532|gb|AAM04167.1| (AE010734) DNA-directed DNA polymerase, family X [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|1518394|emb|CAA94729.1|_96:322 (Z70724) ORF1 [Streptomyces lividans]
- gi|18311129|ref|NP_563063.1|_3:250 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
- gi|18145812|dbj|BAB81853.1| (AP003193) conserved hypothetical protein [Clostridium perfringens]
- gi|15673198|ref|NP_267372.1|_1:258 (NC_002662) histidinol phosphatase [Lactococcus lactis subsp. lactis]
- gi|19862316|sp|Q02150|HIS9_LACLA Histidinol-phosphatase (HolPase)
- gi|12724185|gb|AAK05314.1|AE006353_13 (AE006353) histidinol phosphatase [Lactococcus lactis subsp. lactis]
- gi|18309997|ref|NP_561931.1|_3:248 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
- gi|18144676|dbj|BAB80721.1| (AP003189) conserved hypothetical protein [Clostridium perfringens]
- gi|478083|pir||D47754_1:258 orf13 3' to hisIE - Lactococcus lactis subsp. lactis
- gi|2565149|gb|AAB81911.1| (U92974) unknown [Lactococcus lactis]
- gi|15615934|ref|NP_244238.1|_12:253 (NC_002570) BH3372~unknown conserved protein in others [Bacillus halodurans]
- gi|10175995|dbj|BAB07091.1| (AP001518) BH3372~unknown conserved protein in others [Bacillus halodurans]
- gi|15894377|ref|NP_347726.1|_2:248 (NC_003030) Predicted metal-dependent phosphoesterase (PHP family), YciV ortholog [Clostridium acetobutylicum]
- gi|15024008|gb|AAK79066.1|AE007625_10 (AE007625) Predicted metal-dependent phosphoesterase (PHP family), YciV ortholog [Clostridium acetobutylicum]
- gi|14521038|ref|NP_126513.1|_2:210 (NC_000868) hypothetical protein [Pyrococcus abyssi]
- gi|7517882|pir||G75128 hypothetical protein PAB0560 - Pyrococcus abyssi (strain Orsay)
- gi|5458255|emb|CAB49744.1| (AJ248285) hypothetical protein [Pyrococcus abyssi]
- gi|14591128|ref|NP_143203.1|_2:210 (NC_000961) hypothetical protein [Pyrococcus horikoshii]
- gi|7519083|pir||F71002 hypothetical protein PH1316 - Pyrococcus horikoshii
- gi|3257739|dbj|BAA30422.1| (AP000006) 216aa long hypothetical protein [Pyrococcus horikoshii]
- gi|15678578|ref|NP_275693.1|_333:546 (NC_000916) DNA-dependent DNA polymerase family X [Methanothermobacter thermautotrophicus] [Methanothermobacter thermautotrophicus str. Delta H]
- gi|7430182|pir||G69172 DNA-dependent DNA polymerase family X - Methanobacterium thermoautotrophicum (strain Delta H)
- gi|2621626|gb|AAB85056.1| (AE000838) DNA-dependent DNA polymerase family X [Methanothermobacter thermautotrophicus str. Delta H]
- gi|18977862|ref|NP_579219.1|_2:209 (NC_003413) hypothetical protein [Pyrococcus furiosus DSM 3638]
- gi|18893618|gb|AAL81614.1| (AE010250) hypothetical protein [Pyrococcus furiosus DSM 3638]
- gi|20808251|ref|NP_623422.1|_2:240 (NC_003869) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
- gi|20516849|gb|AAM25026.1| (AE013135) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
- gi|20090153|ref|NP_616228.1|_3:203 (NC_003552) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|19915137|gb|AAM04708.1| (AE010798) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|21228391|ref|NP_634313.1|_2:200 (NC_003901) hypothetical protein [Methanosarcina mazei Goe1]
- gi|20906864|gb|AAM31985.1| (AE013471) hypothetical protein [Methanosarcina mazei Goe1]
- gi|20090155|ref|NP_616230.1|_3:204 (NC_003552) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|19915139|gb|AAM04710.1| (AE010798) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|15791255|ref|NP_281079.1|_1:244 (NC_002607) Vng2493c [Halobacterium sp. NRC-1]
- gi|10581888|gb|AAG20559.1| (AE005127) Vng2493c [Halobacterium sp. NRC-1]
- gi|7451271|pir||C69176_8:225 conserved hypothetical protein MTH576 - Methanobacterium thermoautotrophicum (strain Delta H)
- gi|20093609|ref|NP_613456.1|_2:228 (NC_003551) Predicted phosphatase of the PHP family [Methanopyrus kandleri AV19]
- gi|19886471|gb|AAM01386.1| (AE010316) Predicted phosphatase of the PHP family [Methanopyrus kandleri AV19]
- gi|15805494|ref|NP_294190.1|_326:548 (NC_001263) conserved hypothetical protein [Deinococcus radiodurans]
- gi|7471437|pir||C75515 conserved hypothetical protein - Deinococcus radiodurans (strain R1)
- gi|6458154|gb|AAF10047.1|AE001906_3 (AE001906) conserved hypothetical protein [Deinococcus radiodurans]
- gi|18309954|ref|NP_561888.1|_1:251 (NC_003366) probable histidinol phosphatase [Clostridium perfringens]
- gi|18144632|dbj|BAB80678.1| (AP003188) probable histidinol phosphatase [Clostridium perfringens]
- gi|15669485|ref|NP_248295.1|_1:216 (NC_000909) conserved hypothetical protein [Methanococcus jannaschii] [Methanocaldococcus jannaschii]
- gi|2128772|pir||F64461 hypothetical protein MJ1295 - Methanococcus jannaschii
- gi|1591933|gb|AAB99302.1| (U67570) conserved hypothetical protein [Methanococcus jannaschii] [Methanocaldococcus jannaschii]
- gi|18310038|ref|NP_561972.1|_5:266 (NC_003366) histidinol phosphatase [Clostridium perfringens]
- gi|18144717|dbj|BAB80762.1| (AP003189) histidinol phosphatase [Clostridium perfringens]
- gi|18310865|ref|NP_562799.1|_1:248 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
- gi|18145547|dbj|BAB81589.1| (AP003192) conserved hypothetical protein [Clostridium perfringens]
- gi|19075372|ref|NP_587872.1|_1:270 (NC_003421) histidinol-phosphatase [Schizosaccharomyces pombe]
- gi|3183028|sp|O14059|HIS9_SCHPO Probable histidinol-phosphatase (HolPase)
- gi|7490638|pir||T41045 histidinol-phosphatase - fission yeast (Schizosaccharomyces pombe)
- gi|3451302|emb|CAA20439.1| (AL031324) histidinol-phosphatase [Schizosaccharomyces pombe]
- gi|11498832|ref|NP_070061.1|_2:199 (NC_000917) conserved hypothetical protein [Archaeoglobus fulgidus]
- gi|7483103|pir||H69403 conserved hypothetical protein AF1233 - Archaeoglobus fulgidus
- gi|2649349|gb|AAB90011.1| (AE001019) conserved hypothetical protein [Archaeoglobus fulgidus]
- gi|15895984|ref|NP_349333.1|_1:245 (NC_003030) Predicted PHP family hydrolase [Clostridium acetobutylicum]
- gi|18202318|sp|P58291|HIS9_CLOAB Probable histidinol-phosphatase (HolPase)
- gi|15025762|gb|AAK80673.1|AE007770_6 (AE007770) Predicted PHP family hydrolase [Clostridium acetobutylicum]
- gi|17230432|ref|NP_486980.1|_28:224 (NC_003272) hypothetical protein [Nostoc sp. PCC 7120]
- gi|17132034|dbj|BAB74639.1| (AP003591) ORF_ID:alr2940~hypothetical protein [Nostoc sp. PCC 7120]
- gi|18310352|ref|NP_562286.1|_2:239 (NC_003366) probable histidinol phosphatase [Clostridium perfringens]
- gi|18145032|dbj|BAB81076.1| (AP003190) probable histidinol phosphatase [Clostridium perfringens]
- gi|16264478|ref|NP_437270.1|_24:234 (NC_003078) conserved hypothetical protein [Sinorhizobium meliloti]
- gi|15140615|emb|CAC49130.1| (AL603644) conserved hypothetical protein [Sinorhizobium meliloti]
- gi|15805497|ref|NP_294193.1|_4:234 (NC_001263) histidinol phosphatase, putative [Deinococcus radiodurans]
- gi|18203432|sp|Q9RX45|HIS9_DEIRA Probable histidinol-phosphatase (HolPase)
- gi|7473516|pir||F75515 probable histidinol phosphatase - Deinococcus radiodurans (strain R1)
- gi|6458156|gb|AAF10049.1|AE001906_5 (AE001906) histidinol phosphatase, putative [Deinococcus radiodurans]
- gi|21226610|ref|NP_632532.1|_6:173 (NC_003901) Isoleucyl-tRNA synthetase [Methanosarcina mazei Goe1]
- gi|20904888|gb|AAM30204.1| (AE013276) Isoleucyl-tRNA synthetase [Methanosarcina mazei Goe1]
- gi|20799582|gb|AAM28554.1|_4:179 (AF495474) glyceraldehyde-3-phosphate dehydrogenase [Macrococcus caseolyticus]
- gi|15643567|ref|NP_228613.1|_2:218 (NC_000853) conserved hypothetical protein [Thermotoga maritima]
- gi|18203585|sp|Q9WZR1|HIS9_THEMA Probable histidinol-phosphatase (HolPase)
- gi|7462247|pir||E72330 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
- gi|4981334|gb|AAD35886.1|AE001748_2 (AE001748) conserved hypothetical protein [Thermotoga maritima]
- gi|20092421|ref|NP_618496.1|_1:167 (NC_003552) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|19917677|gb|AAM06976.1| (AE011070) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|20090633|ref|NP_616708.1|_16:208 (NC_003552) ribonuclease P, subunit p30 [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|19915676|gb|AAM05188.1| (AE010857) ribonuclease P, subunit p30 [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
- gi|20808955|ref|NP_624126.1|_1:245 (NC_003869) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
- gi|20517619|gb|AAM25730.1| (AE013201) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
- gi|14600437|ref|NP_146951.1|_24:225 (NC_000854) hypothetical protein [Aeropyrum pernix]
- gi|7515550|pir||H72761 hypothetical protein APE0085 - Aeropyrum pernix (strain K1)
- gi|5103473|dbj|BAA78994.1| (AP000058) 243aa long hypothetical protein [Aeropyrum pernix]
- gi|21228720|ref|NP_634642.1|_16:211 (NC_003901) hypothetical protein [Methanosarcina mazei Goe1]
- gi|20907229|gb|AAM32314.1| (AE013507) hypothetical protein [Methanosarcina mazei Goe1]
- gi|15678604|ref|NP_275719.1|_5:164 (NC_000916) conserved protein [Methanothermobacter thermautotrophicus] [Methanothermobacter thermautotrophicus str. Delta H]
- gi|2621654|gb|AAB85082.1| (AE000840) conserved protein [Methanothermobacter thermautotrophicus str. Delta H]
- gi|21314372|gb|AAM46912.1|AF508325_1_325:430 (AF508325) DNA polymerase III C [Enterococcus faecalis]
- gi|21401801|ref|NP_657786.1|_329:446 (NC_003995) EXOIII, exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other [Bacillus anthracis A2012] [Bacillus anthracis str. A2012]
- gi|15614981|ref|NP_243284.1|_330:410 (NC_002570) DNA polymerase III (alpha subunit) [Bacillus halodurans]
- gi|13959348|sp|Q9KA72|DPO3_BACHD DNA polymerase III polC-type (PolIII)
- gi|10175038|dbj|BAB06137.1| (AP001515) DNA polymerase III (alpha subunit) [Bacillus halodurans]
- gi|20807370|ref|NP_622541.1|_2:219 (NC_003869) predicted metal-dependent phosphoesterases (PHP family) [Thermoanaerobacter tengcongensis]
- gi|20515888|gb|AAM24145.1| (AE013055) predicted metal-dependent phosphoesterases (PHP family) [Thermoanaerobacter tengcongensis]
- gi|13959345|sp|Q9CDT7|DPO3_LACLA_507:587 DNA polymerase III polC-type (PolIII)
- gi|15674106|ref|NP_268281.1|_527:607 (NC_002662) DNA polymerase III, alpha chain (EC 2.7.7.7) [Lactococcus lactis subsp. lactis]
- gi|12725180|gb|AAK06222.1|AE006440_8 (AE006440) DNA polymerase III, alpha chain (EC 2.7.7.7) [Lactococcus lactis subsp. lactis]
- gi|18310673|ref|NP_562607.1|_347:457 (NC_003366) DNA polymerase III alpha subunit [Clostridium perfringens]
- gi|18145354|dbj|BAB81397.1| (AP003191) DNA polymerase III alpha subunit [Clostridium perfringens]
- gi|15902295|ref|NP_357845.1|_337:423 (NC_003098) DNA polymerase III, alpha subunit [Streptococcus pneumoniae R6]
- gi|15457800|gb|AAK99055.1| (AE008406) DNA polymerase III, alpha subunit [Streptococcus pneumoniae R6]
- gi|9789541|gb|AAF98345.1|_338:422 (AF280761) DNA polymerase III alpha chain [Streptococcus pyogenes]
- gi|15675759|ref|NP_269933.1|_338:422 (NC_002737) DNA polymerase III (alpha subunit) [Streptococcus pyogenes] [Streptococcus pyogenes M1 GAS]
- gi|14194673|sp|Q9FDF9|DPO3_STRPY DNA polymerase III polC-type (PolIII)
- gi|13622981|gb|AAK34654.1| (AE006619) DNA polymerase III (alpha subunit) [Streptococcus pyogenes M1 GAS]
- gi|19746871|ref|NP_608007.1|_338:422 (NC_003485) DNA polymerase III alpha chain [Streptococcus pyogenes MGAS8232]
- gi|19749113|gb|AAL98506.1| (AE010106) DNA polymerase III alpha chain [Streptococcus pyogenes MGAS8232]
- gi|15900208|ref|NP_344812.1|_337:422 (NC_003028) DNA polymerase III, alpha subunit, Gram-positive type [Streptococcus pneumoniae TIGR4]
- gi|21263563|sp|Q97SQ2|DPO3_STRPN DNA polymerase III polC-type (PolIII)
- gi|14971745|gb|AAK74452.1| (AE007340) DNA polymerase III, alpha subunit, Gram-positive type [Streptococcus pneumoniae TIGR4]
- gi|15618576|ref|NP_224862.1|_1:83 (NC_000922) DNA Polymerase III Alpha [Chlamydophila pneumoniae CWL029]
- gi|15836198|ref|NP_300722.1| (NC_002491) DNA polymerase III alpha [Chlamydophila pneumoniae J138]
- gi|16752374|ref|NP_444633.1| (NC_002179) DNA polymerase III, alpha subunit [Chlamydophila pneumoniae AR39]
- gi|14194705|sp|Q9Z7N8|DP3A_CHLPN DNA polymerase III alpha subunit
- gi|7434837|pir||B72050 DNA polymerase III, alpha chain CP0081 [imported] - Chlamydophila pneumoniae (strains CWL029 and AR39)
- gi|4376966|gb|AAD18805.1| (AE001649) DNA Polymerase III Alpha [Chlamydophila pneumoniae CWL029]
- gi|7189016|gb|AAF37967.1| (AE002171) DNA polymerase III, alpha subunit [Chlamydophila pneumoniae AR39]
- gi|8979038|dbj|BAA98873.1| (AP002547) DNA polymerase III alpha [Chlamydophila pneumoniae J138]
- gi|15893807|ref|NP_347156.1|_11:128 (NC_003030) DNA polimerase III, alpha chain (dnaE) [Clostridium acetobutylicum]
- gi|15023379|gb|AAK78496.1|AE007566_6 (AE007566) DNA polimerase III, alpha chain (dnaE) [Clostridium acetobutylicum]
- gi|15896683|ref|NP_350032.1|_338:540 (NC_003030) DNA polymerase III (alpha subunit) [Clostridium acetobutylicum]
- gi|15026532|gb|AAK81372.1|AE007841_7 (AE007841) DNA polymerase III (alpha subunit) [Clostridium acetobutylicum]
- gi|20808235|ref|NP_623406.1|_3:318 (NC_003869) DNA polymerase III alpha subunit [Thermoanaerobacter tengcongensis]
- gi|20516832|gb|AAM25010.1| (AE013134) DNA polymerase III alpha subunit [Thermoanaerobacter tengcongensis]
- gi|15643342|ref|NP_228386.1|_268:453 (NC_000853) DNA polymerase III, alpha subunit [Thermotoga maritima]
- gi|6225287|sp|Q9ZHF6|DPO3_THEMA DNA polymerase III polC-type (PolIII)
- gi|7447209|pir||C72360 DNA polymerase III, alpha subunit - Thermotoga maritima (strain MSB8)
- gi|3930535|gb|AAC80438.1| (AF065313) DNA polymerase III; family C DNA polymerase [Thermotoga maritima]
- gi|4981093|gb|AAD35661.1|AE001732_6 (AE001732) DNA polymerase III, alpha subunit [Thermotoga maritima]

              10            20        30        40             50      
              |             |         |         |              |      
   1 MYPVDLHMHT.VAST...HAYSTLSDYIAQAKQKGIKLFAITDHGPD.....MEDAPHH.....W
   2 -VIYDLHSHT.TASD...G-LLTPETLVHRAVEMRVGTLAITDHDTT.....AAIPAAR.....E
   3 -VIYDLHSHT.TASD...G-LLTPETLVHRAVEMRVGTLAITDHDTT.....AAIPAAR.....E
   4 -VIYDLHSHT.TASD...G-CLTPEALVHRAVEMRVGTLAITDHDTT.....AAIAPAR.....E
   5 -VIYDLHSHT.TASD...G-CLTPEALVHRAVEMRVGTLAITDHDTT.....AAIAPAR.....E
   6 MYPVDLHMHT.VAST...HAYSTLSDYIAQAKQKGIKLFAITDHGPD.....MEDAPHH.....W
   7 MYPVDLHMHT.VAST...HAYSTLSDYIAQAKQKGIKLFAITDHGPD.....MEDAPHH.....W
   8 FTLYDLHSHT.TASD...G-TLTPSELVIRAAQMRVGVLAITDHDTT.....AGLAEAA.....A
   9 MYPVDLHMHT.VAST...HAYSTLSDYIAEAKRKGIKLFAITDHGPD.....MEDAPHH.....W
  10 -MRIDLHSHT.TASD...G-RFTYQQLIDRAVSFEIDVLAITDHDTV.....AALADAR.....A
  11 MYPVDLHMHT.VAST...HAYSTLHDYIAEAKLKNIKLFAITDHGPD.....MADAPHY.....W
  12 ----------.----...-----------------VGTLAITDHDTT.....AAIPAAR.....E
  13 -TIYDLHCHS.TASD...G-VLSPTEVVARAVEKGVNVLALTDHDTT.....AGLAEAR.....L
  14 PINADLHCHS.TVSD...G-LLAPREVAARAAAHGVTLWALTDHDEV.....GGQAAAR.....E
  15 EMFADLHMHS.KASD...G-TNSPREVVRLAKAHGLSCIALTDHDTV.....DGLQEAI.....E
  16 ---IDLHCHS.TVSD...G-MLSPAEVVRLAHQNGCTLLALTDHDHT.....GGIAEAR.....A
  17 ---IDLHCHS.TVSD...G-MLSPAEVVRLAHQNGCTLLALTDHDHT.....GGIAEAR.....A
  18 -LEVETHCHT.IASG...HAYNNLEEMVLEAQKKGLKGICITDHGPE.....MPGSCSS.....L
  19 -LAVDTHTHT.YASG...HAYSTLIENARAAKQNGLTLFCTTDHAES.....MPGAPHY.....W
  20 RLVLDTHTHT.IASG...HAFSTIIENAREAFRKGLQLICITDHGPE.....MPGGPHI.....Y
  21 DIRGDLHMHT.TWSD...G-AYAIPEMIEACIAKGYEYMVITDHGKF.....LRVANGLde6llE
  22 KYLIDLHTHT.IVSG...HAYTTLLENIKQASQIGIKILGTSEHGPK.....MPGAPHI.....W
  23 -MRVDLHCHS.TASD...G-VLAPAALVQRAHEKGVGLLALTDHDTL.....EGLPEAH.....Q
  24 DIRADLHMHT.TWSD...G-AHSIEEMAEAARQRGYEYIAITDHSKFlr6ngLSEERLK.....E
  25 DIRGDLHMHT.TWSD...G-AYAIPEMIEACIAKGYEYMVITDHGKF.....LRVANGLde6llE
  26 DIQGDLHMHT.TWSD...G-AFSIEEMVQACRARGYKFMAITDHSQYlk6ngLTKERLR.....E
  27 DIKGVFHVHT.TYSD...G-RNSLEDMVRKARDLGYKYIAITDHSKS.....AFYANGLte6llR
  28 DINGDIHMHT.TYSD...G-AFSIRDMVEANIAKGYKFMVITDHSQSlr6ngLQVERLL.....R
  29 QIKGDLHMHS.TWSD...G-AFSIREMAEACIKKGYQYMAITDHSQYlk6ngLTAERLK.....Q
  30 DINGDIHMHT.TYSD...G-AFSIRDMVEANIAKGYKFMVITDHSQSlr6ngLQVERLL.....R
  31 DLRGDLHMHT.DYSE...G-AESLETMVEKAESMGYEYIAVTDHSRSqr6ngMDIETLK.....E
  32 --NSDLHMHS.TASD...G-GYSPTELMEKCHQANLKFVALTDHDTV.....NGIEEAK.....Q
  33 ALRGDLHLHS.NWSD...G-SAPIEEMMATAAALGHQYCALTDHSPRlt6ngLSPDRLR.....K
  34 RLRGDCHLHS.DWSD...G-GSPIEEMGRTAAALGHEWAALTDHSPRlt6rgLSPARLR.....E
  35 DIKGDLHMHT.NWSD...G-VNTLEEMVETAYKLGYQYIVIGDHSQSar6ngLDPERYK.....Q
  36 DLKGDFHLHT.DYSE...G-RASLETMVKKAETMGYEYIAVTDHSRSqr6hgMEIDTLK.....A
  37 RLRGDCHLHA.DWSD...G-GSPMEEMGRTAAALGHEWAALTDHSPRlt6rgLSPARLR.....E
  38 LVRTDLHMHT.RASD...G-TLTPKELLKEIVEKDIKLFSVTDHDSI.....GSLEEMQ.....D
  39 MKKLDYHFHS.HFSA...DSEELPRKHVTEAIAHGLEEICFTEHRDFyfpgmDFSLNLP.....E
  40 -INAEFHCHS.LASD...G-TLSPKEVIAEAKKSGISLIALTDHDIT.....SGLDEAK.....E
  41 MKKLDYHFHS.HFSA...DSEELPRKHVIEAIAYGLEEICFTEHRDFyfpgmDFSLNLP.....E
  42 ---FDLHIHT.TASD...G-EYSPTAIVKKAKEIGLRTIAITDHDTL.....DGIEEAV.....I
  43 YLKGDFHIHT.NASD...G-KYTPEKVLELAKTAGINILAITDHDTT.....SSVKKAI.....A
  44 ---MDLHTHT.IYSD...G-IGMVRDNVAWAEKRGLKIVGISDHIHY.....FTPSKFS.....A
  45 ---MDLHTHT.VYSD...G-IGLIRDNVAWAEKRGLKIVGISDHIHF.....FTPSRFS.....A
  46 DIRGDLHMHS.LFSD...G-IDSMEQMAEYASVLGREYIAITDHARY.....IDDPDAY.....F
  47 ----DLHTHT.IYSD...G-IGSVIDNVNMAEIRGLRLLGISDHIHF.....FTPSKFL.....K
  48 RIFADYHTHT.IYSH...G-KGTIEENVKKAVELGLKAIAITDHGPAhvfygMRKKDFK.....K
  49 -QLIDLHTHT.IFSD...G-ELLPSELVRRAVIHGYEAIALTDHADY.....TNLEQLL.....D
  50 ---IDLHTHT.IFSD...G-ELIPSELVRRAVIHGYEAIALTDHADY.....TNLEQLL.....D
  51 -QLIDLHTHT.IFSD...G-EFLPSELVRHAVLHGYEAVAITDHADH.....TNLEWLL.....E
  52 MVHADLHVHT.TNSD...G-TLTIDAVPDAAHDAGVTAVAITDHDRL.....HPALDAP.....V
  53 RKRIDLHTHS.LLSD...G-ELLPSELARRACVLGHEAIAITDHIDA.....SNINTIT.....N
  54 RLRADLHTHT.VYSD...G-HGTPLENVLAAEERGLETVALTDHGPAspdg.LTDRSFR.....R
  55 DLRGMIHTHS.TWSD...G-GASIREMAEATLTLGHEFLGTADHSRAay6ngLTIERLR.....E
  56 -MRSNYHTHT.YRCN...HATGTIEDYVKEAIKANIDEIGISDHLPHp10hrMAYEDLE.....D
  57 -MRFDFHTHT.VFSD...G-ELIPAELVRRARVLKHRAIAITDHADF.....SNYKELIe....K
  58 -TKRDGHVHS.TYCPh..GSNDTLDMYIDTALKNGITEITFTEHMPLp12saLPMERLE.....E
  59 -MLYDCHIHT.EFSA...DSELKIKDILEKAKKNNLGII-TTEHLDYn10aeLDIEGYL.....K
  60 -MPISSHSHSgQFCL...HAQGKLEDVIQEAIQQGFQSFSFTEHTPR.....DRVEDLYp16fdE
  61 ---IDLHIHS.NYSD...G-QGSVEEIARRAKERGLKAIAIVDHSIElp...FGLTEKK.....A
  62 -MVFDTHLHT.LFST...DSKMNIEEAIDAGEKKNLGII-ITEHID-.....LNYPVKG.....E
  63 PKLFNFHMHT.VYSD...G-RLQPSVLMEQAIAIGLQGFAITDHHTV.....GGYEAAQ.....A
  64 LKKINFHTHT.KRCK...HAKGEDKDYIDAAIKNNLDILGFSDHGPYpd8lrMNFNELE.....E
  65 QLNVEFQVHT.SWTD...G-QATALEILQTASERGLAELAFTEHVR-.....EDTSWFP.....E
  66 --LCDSHLHT.PLCG...HATGTPREYAQAALDAGLSGLCFTDHMPMpr9wrMKLEQLP.....E
  67 IMKFDLHVHS.EHSK...DSNSSHRDIIEVARRRGLDGFAICDHDTV.....EGGLACA.....E
  68 ----------.----...-----------------------------.....-RIGRLL.....E
  69 ---IDMHLHS.TFSY...DGKAEIDDIISQVQKLGIEHFCITDHYEY.....ENGELVH.....D
  70 -MKFDLHVHS.EYSR...DSESSHEDILENALKRGLDGFAICDHDTV.....EGGLACA.....K
  71 ----------.---D...G-DSTAQEQVSLGRHFGFSGIALANHSDR.....LPDRKPI.....L
  72 -MPADYHVHI.ENGP...FTIEWLKEFVNQGLKRGLKEIGISEHGHRf26siEDYVELI.....K
  73 LMLVELHSHT.TVSD...G-FQTPMEIVKIAAKAGLAAIAVTDHDTF.....RGSSLAK.....R
  74 ----------.---D...G-ANAVEELSSLSRHLGYSGIALANHSDK.....LPSKKPV.....L
  75 ----------.----...-----------------------------.....-------.....-
  76 EKRVELHMHS.NMSTm..DATNKVGDLVAQAGKWGHKAIAITDHGGA.....QAFPDAH.....A
  77 EKRVELHLHT.PMSQm..DAVTPVSKLVAQAGKWGHEAIAVTDHAVA.....QSFPEAY.....S
  78 EKRVELHLHT.AMSQm..DGISSAGAYVTQASKWGHKAIAITDHGVV.....QAFPEAY.....G
  79 MVYYDLHIHT.CLSPcasD-DMTPNNIVNMALLKGLDVIAVTDHNSA.....LNVEAVY.....R
  80 EKRVEFHAHT.NMSQm..DAIPSASSLVAQAAKWGHKAIAITDHGGL.....QSFPEAH.....S
  81 EKRVEFHAHT.NMSQm..DAIPSASSLVAQAAKWGHKAIAITDHGGL.....QSFPEAH.....S
  82 EKRVELHMHT.TMSSm..DAVTAASKIVERAAKFGHKAVAITDHGVV.....QAFPDAQ.....I
  83 -RRVEFHAHT.NMSTm..DALPEVEEIVATAAKWGHKAVAITDHGNV.....QSFPHGY.....K
  84 QKRVELHAHT.NMSTm..DALPTVESLIDTAAKWGHKAIAITDHANV.....QSFPHGY.....H
  85 QKRVELHAHT.NMSTm..DALPTVESLIDTAAKWGHKAIAITDHANV.....QSFPHGY.....H
  86 QKRVELHAHT.NMSTm..DALPTVESLIDTAAKWGHKAVAITDHANV.....QSFPHGY.....H
  87 -RRVEFHAHT.NMSTm..DALPEVEEIVATAAKWGHKAVAITDHGNV.....QSFPHGY.....K
  88 MTWIPLHCHS.QYSVl..DAMSSIKDFVAKGQEFGIPALALTDHGNL.....YGAVDFY.....K
  89 --FVHLHVHT.EYSLl..DGSGKVKKLVERAKELGMKSIAITDHGAM.....YGCVEFY.....K
  90 EKRVELHMHT.KMSQm..DAMTSATDLIKRAMSWGMKSIAITDHGVV.....QAFPEAH.....K
  91 AMFVHLHVHT.EYSLl..DGSCRIKDLIAKTKELGMKAIAITDHGAM.....YGVIDFY.....K
  92 VKRVELHAHT.KFSDq..DAITDVNEYVKRAKEWGFPAIALTDHGNV.....QAIPYFY.....D


                60          70            80         90         100    
                |           |             |          |           |    
   1 HFINMRIW...PRVVD..GVGILRGIEAN..IKN..VDGEIDCSGKM.FD..SLDLIIAGFHEPV
   2 ------EI...SRCGL..ALNLIPGVEIS..TVW..-----------.--..-------------
   3 ------EI...SRSGL..ALNLIPGVEIS..TVW..-----------.--..-------------
   4 ------EI...SRSGL..ALNLIPGVEIS..TVW..-----------.--..-------------
   5 ------EI...SRSGL..ALNLIPGVEIS..TVW..-----------.--..-------------
   6 HFINMRIW...PRVVD..GVGILRGIEAN..IKN..VDGEIDCSGKM.FD..SLDLIIAGFHEPV
   7 HFINMRIW...PRVVD..GVGILRGIEAN..IKN..VDGEIDCSGKM.FD..SLDLIIAGFHEPV
   8 ------AI...EQHQL..ALRLIPGVEIS..TLW..-----------.--..-------------
   9 HFINMRIW...PRLVD..GVGILRGIEAN..IKN..INGEIDCSGKM.FD..SLDLIIAGFHEPV
  10 Y------I...AQQQY..PLQLVNGIEIS..TVW..-----------.--..-------------
  11 HFMNMRVW...PRLVD..GVGILRGIEAN..IKN..LDGDIDCTGPM.LD..AVDLLIAGFHEPV
  12 ------EI...SRSGL..ALNLIPGVEIS..TVW..-----------.--..-------------
  13 --------...AAQQT..DLTLISGVEIS..TTW..-----------.--..-------------
  14 --------...AAESL..GMDYLAGVEIS..VTW..-----------.--..-------------
  15 --------...ASFEL..GIEVIPGIEFN..CYY..-----------.--..-------------
  16 --------...EADKL..GLRLINGVEIS..VTW..-----------.--..-------------
  17 --------...EADRL..GLRLINGVEIS..VTW..-----------.--..-------------
  18 YFYNLIVV...PRKIN..GIMVFRGCEAN..IVD..YEGRIDIPEDA.LK..RLDFVIASLHDVC
  19 FFSNQRIL...PRFLE..GVGVIRGVEAN..ILN..TQGEIDLHPSV.DH..NLDWVIGSFHEPV
  20 YFGNLKVI...PEKIE..GVEILKGVEAN..IMD..EEGRIDLPERI.LK..KLDIVIASLHDEC
  21 QQAEIKKV...AANYP..EIDVYSGVEMD..ILA..-DGSLDFDDDT.LK..QLDFVIASIHSS-
  22 YFGNMNKV...PRKIY..DVTVLRGCEAD..ILN..SNGDLDIPERI.QN..ELDYIIASLHDVC
  23 --------...AAARL..GIELVNGVELS..CTW..-----------.--..-------------
  24 QHAKIREL...NERYD..DFTIFTGIEMD..ILP..-DGTLDYEDPI.LA..EVDFVIASIHSS-
  25 QQAEIKKI...AAKYP..EIDVYSGVEMD..ILA..-DGSLDFDDET.LK..QLDFVIASIHSS-
  26 QAKEIERM...NEKYP..DITILRGIEMD..ILP..-DASLDFDDEV.LA..ELDYVIGAIHSS-
  27 QWEEIDEL...NKKYP..DIVILKGIESD..ILP..-DGSLDYEEEI.LK..RFDMVVASIHSH-
  28 QNEEIKAL...DKEYS..EIDIYSGTEMD..ILP..-DGSLDYDDEI.LA..QLDYVIGAIHQS-
  29 QAKEIDAL...NAEFE..NFRILKGVEMD..ILP..-DGTLDYDDDV.LA..EMDIVIASIHSS-
  30 QNEEIKAL...DKEYS..EIDIYSGTEMD..ILP..-DGSLDYDDEI.LA..QLDYVIGAIHQS-
  31 QWKEIKS-...LSKRF..RIKVLRGSEVE..ILK..-DGSLDYPDEI.LK..ELDVVVGAVHSG-
  32 --------...TAHRL..GFILIPGIELS..TKA..-----------.--..-------------
  33 QLDVIDEL...REKFA..PLRILTGIEVD..ILE..-DGSLDQEPEM.LD..RLDIVVASVHSK-
  34 QLDVVAEL...NATWA..PFRLLTGIECD..ILD..-DGSLDQEPEL.LE..RLDVVVVSVHSK-
  35 QWKEIDRL...NKEYNpkGFYILKGAEVD..ILP..-DGSLDLPDEV.LE..QFDFVVASVHSR-
  36 QWEEIKK-...LSKRF..KIKILRGSEVE..VLK..-DGSLDYPDEI.LK..ELDIVVGAVNSG-
  37 QLDVVAEL...NATWA..PFRLLTGIECD..ILD..-DGSLDQEPEL.LE..RLDVVVVSVHSK-
  38 --------...LTEEM..DIKFIPGVEVS..SII..-----------.--..-------------
  39 YFQEINRLq..AEFKD..KIKIKIGLEMG..IDL..RFKSEINQFID.SA..PFDFVIASVHEI-
  40 --------...AAKEL..DIQFIPGIELS..CEH..-----------.--..-------------
  41 YFQEINRLq..AEFKD..EINIKIGLEMG..IDL..RFKSEINQFID.SA..PFDFVIASVHEI-
  42 --------...AGKRH..GINVIPAIELT..TKY..-----------.--..-------------
  43 --------...VGNEL..GIKVLPGIELS..TLK..-----------.--..-------------
  44 YINEIRI-...AKEES..DIVVLAGIEAN..ILE..--NGPDITDEF.RK..RLDYVIASVHEW-
  45 YINEINV-...IKEES..EIVVLAGIEAN..ILE..--NGPDITDEF.RK..KLDYAIASVHEW-
  46 ------RA...AERIE..EIDVLAGVEVS..ILH..-DGNLEVPDGA.LK..NFDLVIASIHDP-
  47 YVNEVRS-...IGREA..EIPVLVGIEAN..ITE..--NGPDVTEDF.AK..HLDYVIASVHDW-
  48 MRDEIDRL...REKYS..QIKILMGVEAN..LIS..IEGDIDVPDEL.LK..YLDILLVGYHTGI
  49 AAKKAKY-...LEEEW..DIRVLPGVELT..HVP..-PRKIAPMAKK.AK..ELGAEIVVVHGE-
  50 AAKKAKY-...LEEEW..DIRVLSGVELT..HVP..-PRKIAPMAKK.AK..ELGAEIVVVHGE-
  51 AAKKAKY-...LEEEW..DIRVLSGVELT..HVP..-PRKIAPLSKK.AK..ELGAEIVVVHGE-
  52 --------...-TVRD..DITVIHGIELR..VDT..-----------.--..-------------
  53 LIDAVED-...IGDNW..DITVIPGAEIT..HAP..-VEIIEKLAVR.AR..RLGAEVIVVHGE-
  54 LVAEARE-...AEKLC..SVRVYVGVEAN..IVS..ISGEIDATPAM.LS..ESDIVLAAIHNPR
  55 QLKEIREL...--QRA..GLPIVAGSEVD..ILD..-DGSLDFPDDV.LG..ELDYVVVSVHSN-
  56 YFGKIEEAi..EKYGD..KISIKRSIECE..YFP..DFGWLYEELKD.KY..KADYLALGVHFFP
  57 TTIAKEEL...KKYWD..DIIVIVGVELT..HIP..-PKSIPKMAKK.AK..DLGAEIVVVHGE-
  58 YIKGITELk..EKVKD..KIKVNLGLEVD..YVEgyEEETKAILNKY.GK..YLDDAILSVHIVK
  59 ------E-...YSKYR..GENMQQGVELGlaMNN..VDENFAFYEKY.KD..KFDMIIGSIHSI-
  60 YVNEARRLk..QNYGD..QINILIGAETEy.IRP..ESVELLKSLNT.KY..NLDYFVGSVHHV-
  61 RMREIEIEn..AASLY..GIKIYSGIECS..INA..-AGEIVLPDF-.--..DFDFIIASVHEF-
  62 FVFDIDKYfkeYNKYR..SNKVLLGVEIG..MGE..EIKEQNKSIND.KY..EFDYVLGSIHLLN
  63 WLENWKWN...NPGVT..TPHLWSGVEIN..ANL..-----------.--..-------------
  64 YKSTLEKLk..IKFKN..FIQIKIGLEIE..YLP..SDDFYYNYLKN.EL..KFDYLALGQHLFL
  65 FRDEIRSA...ARGFD..HMSVYVGCETK..AMD..DDGRLDVSQDV.LD..GCDIVLGVVHRLP
  66 YIAEIQAVq..QEFAG..RLDVRLGLEAD..FHP..--GTEKFVEKV.LGmfDWDYVIGSVHYLG
  67 ------KA...LELGL..EITVLPGVEVS..SSK..-----------.--..-------------
  68 QHARVKAL...DAQYP..EIDIYSGVEMD..ILA..-DGEMDYSNDV.LA..QLDYCIGAIHQS-
  69 --FNVEEY...FLTME..KYDLPKGAEIS..WDG..-VGEAVFPD--.--..GFDYLLLGIHRY-
  70 ------KA...LELGL..EITVIPGVEVS..SSK..-----------.--..-------------
  71 --------...-PFIE..GFEVFRGIELV..EEN..PSKLHSLIGKF.RN..SMDVLIV------
  72 --------...EAKQM..GLPVKLGIEAD..YFP..-GKEKEIRDFLtLY..LWDFIIGSVHWID
  73 -------A...AKLLG..GVAVIPAAEVR..SEW..GDVVVLCSNDV.SD..DFPRAI-------
  74 --------...-PSIE..GFEVFRGIELV..EEN..PSKLHGLVGKF.RS..SMDVLIV------
  75 --------...-GDNW..DITVIPGAEIT..HAP..-VEIIEKLAVR.AR..RLGAEVIVVHGE-
  76 --------...AGKKA..GVKILYGVEAN..IVD..-DGVPIAYN--.--..-------------
  77 --------...AGKKA..GVKVIYGVEAN..LVN..-DGVPIAYNE-.--..-------------
  78 --------...ASQKH..GIKVIYGVEAN..LVD..-DGVPIAYNEA.--..-------------
  79 --------...IGRKK..GLIVVPGIEVQ..TKE..-----------.--..-------------
  80 --------...AGKKN..GVKIIYGVEAN..LVE..-DKIPIVYNET.--..-------------
  81 --------...AGKKN..GVKIIYGVEAN..LVE..-DKIPIVYNET.--..-------------
  82 --------...AAKKN..NIKVIYGVEGY..LAD..-NGTPIVINGH.EE..SFDDEYVVFDI--
  83 --------...AAKKA..GIQLIYGIEAN..IVE..-DRVPIVYNEV.EM..DLSEA--------
  84 --------...RARKA..GIKAIFGLEAN..IVE..-DKVPISYEPV.DM..DL-----------
  85 --------...RARKA..GIKAIFGLEAN..IVE..-DKVPISYEPV.DM..DL-----------
  86 --------...RARKA..GIKAIFGLEAN..IVE..-DKVPISYDPV.DM..DL-----------
  87 --------...AAKKA..GIQLIYGMEAN..IVE..-DRVPIVYNEV.EM..DLSE---------
  88 --------...ECTQK..GIQPIIGCECY..IAP..-GSRFDKKKEK.RS..-------------
  89 --------...AAKEV..GIKPIIGCEIY..VAG..KSMHIKHPDAE.NE..TYHLVLLVKNEIG
  90 ------LL...GRDNP..DMKIIYGVEAY..LAP..-DKKPSVTNAK.DQ..SIDTTYC------
  91 --------...EAVAQ..GIKPIIGCEIY..VAP..-RRMQDREYGI.DD..-------------
  92 --------...AAKEA..GIKPIFGIEAY..LVS..-DVEPVIRNLS.DD..S------------


          110            120       130            140       150       1
           |              |         |              |         |        
   1 FAP.HDK.....ATNTQAMIATIASGNVHIISHPGNPK.....YEIDVKAVAEAAAKHQVALEIN
   2 ---.---.....-----------ENHEIHIVGLNIDIA.....HPAMRDFLAQ------------
   3 ---.---.....-----------ENHEIHIVGLNIDIA.....HPAMRDFLAQ------------
   4 ---.---.....-----------ENHEIHIVGLNIDIT.....HPLMCEFLAQ------------
   5 ---.---.....-----------ENHEIHIVGLNIDIT.....HPLMCEFLAQ------------
   6 FAP.HDK.....ATNTQAMIATIASGNVHIISHPGNPK.....YEIDVKAVAEAAAKHQVALEIN
   7 FAP.HDK.....ATNTQAMIATIASGNVHIISHPGNPK.....YEIDVKAVAEAAAKHQVALEIN
   8 ---.---.....-----------ENHEIHIVGLGIDVQ.....HVSLRTLLEA------------
   9 FAP.HDK.....ETNTQAMIATIASGKVHIISHPGNPK.....YPVEVKAIAQAAAKHHVALEIN
  10 ---.---.....-----------QNKDIHIVGLNIDPN.....SEALGQLIAR------------
  11 FPP.QDK.....AANTQAMIATMAQGNVHIISHPGNPK.....YPVDIPAIAQAAAKYNVALELN
  12 ---.---.....-----------ENHEIHIVGLNIDIA.....HPAMRDFLAQ------------
  13 ---.---.....-----------ENRAIHIVGLGFDET.....SAKMTALLRQQAA---------
  14 ---.---.....-----------AGRTLHIVGLGIDPD.....DAALVQGLAR------------
  15 ---.---.....-----------KDQEVHILGYYIDYE.....DRGFVDKLEE------------
  16 ---.---.....-----------RGRTIHVVGLDFDEQ.....DENLQNLLAQ------------
  17 ---.---.....-----------RGRTIHVVGLDFDER.....DENLQNLLAQ------------
  18 IPS.GTV.....SDHTRALIGAIKNPYIHCIGHPGNPL.....YEIDKEEVVLAAKEYKKAIEIN
  19 FHP.ADK.....AAHTQALIETIKGGRVDALGHLGNPH.....FDFDFEQVIACAKAHNVAIEIN
  20 FEPsEDV.....ERNTKALINAIKNPYVDIIGHPGNPI.....YPIDIERVLEAAKEYGKFIEIN
  21 -FQ.QSE.....EEIMKRLKTACENPYVRLIAHPTGRIvv6kpYHVNMKELIKLAKNTGTALELN
  22 IEP.GTI.....EDNTKALLNAMNNPNIDILGHTGNPM.....YPIDIDAVVSKAKEKNVLIEIN
  23 ---.---.....-----------GGATIHVLGYGFDLD.....----------------------
  24 -FS.QPR.....EKIMDRLKTALVNHHVDLIAHPTGRLig6egYDVDVDMLIELAKETNTALELN
  25 -FQ.QSE.....EEIMKRLKTACENPYVRLIAHPTGRIvv6kpYHVNMKELIQLAKSTGTALELN
  26 -FS.QDC.....ETIMKRLRAALENKHVTMIAHPTGRLlg6egYDVDTDLLIELAKETNTVLELN
  27 -FR.MSK.....EEMTKRVIKALENKYTKILGHPTGRLll6dsYEIDVYAVIDAAAHYGKIIEIN
  28 -FN.QSE.....EQIMERLANACRNPYVRHIAHPTGRIig6dgYKPNIEQLMALAEETNTVLEIN
  29 -FN.QPE.....HVIMKRLETALTNKHVDIIAHPTGRLig6agYEIDIDQLIELARKTNTALELN
  30 -FN.QSE.....EQIMERLANACRNPYVRHIAHPTGRIig6dgYKPNIEQLMALAEETNTVLEIN
  31 -FA.ASE.....REMTGRIITALENKHLDILAHPSGRLlg6eaYAVNFGKVFEAAAENGKVMEIN
  32 ---.---.....-----------SGQSVHMLGYGIDWK.....NDTLKRRLDR------------
  33 -LS.MDS.....AAMTRRMVRAVANGHTDVLGHCTGRLi10peSKFDAEAVFTACREHGTAVEIN
  34 -LR.MDA.....RSMTRRMVAAVRDPHADVLGHCTGRLlt8peSAFDADEVFAACAEAGTAVEIN
  35 ---.-FE.....QDNTERIIKAMENPYVNMIGHPTGKQyg6egYPVNIEKLIQKAKETGTALELN
  36 -FS.SSE.....REMTGRIVTALENRHLDILAHPSGRLlg6eaYAVNFGTVFETAAANGKVMEIN
  37 -LR.MDA.....RSMTRRMVAAVRDPHADVLGHCTGRLlt8peSAFDADEVFAACAEAGTAVEIN
  38 ---.---.....-----------NGEQFHILAYNFDKN.....----NKELMSLIENNDRLLQEK
  39 ---.---.....--------------------------.....----------------GDIEVY
  40 ---.---.....-----------KGSTIHILGYFRDDSyk...SEDFQKFLNE------------
  41 ---.---.....--------------------------.....----------------GDIEVY
  42 ---.---.....-----------KGTNVDILGYNVKASe....------KLQAI-----------
  43 ---.---.....-----------NGESIHILGYFRDISye...NKDFQNFLTE------------
  44 FGR.DGA.....HMYIEYVKRAIMDDNVDIIGHFGNSFpw6ypTEEEIREVLELAEAYGKAFEIS
  45 FGR.NGT.....HEYINYVKKAIMDDNVDIIGHFGNSFpw6ypTREEIDEILDLAEAYGKAFEIS
  46 ---.---.....GNLTERLLAAMDHDPVSIIGHPTGRVlgspePVVDIERVIEGAAEAGVALEVN
  47 FGE.GEV.....YRYIERIKLALMDENVTIIGHFGNVFpw6ypTEEQIKEVLDVAEEYGKAFEIS
  48 VPK.SFKd23vrEKNTEAMVKAIKKYRIDIITHPGAKV.....-DIDTRKLARAAKESRTALEIN
  49 --T.IYE.....PVAPGTNAASAACEYVDILAHPGLIS.....-----EEDVRTAAENNVLLELT
  50 --T.ISE.....PVAQGTNAASAACEYVDILAHPGLIS.....-----EEDVRTAAENNVFLELT
  51 --T.ISE.....PVAPGTNSASVACEYVDILAHPGLIS.....-----EEDVQTAVDNNVLLEIT
  52 ---.---.....-----------GPQRVDLLGYGVHGTda...LTAECDRIQR------------
  53 --T.LVE.....PVIPGTNHAAVSCPEVDILAHPGLIT.....-----IEDVELARENDVTLEIS
  54 LIL.ANPgs7lrRAIVHATIRCIESGEVHIIAHPVWILeq7yiTAQEAEEIARVAADHNVGLELN
  55 -FT.LDA.....ARQTERLIRAVSHPLVTVLGHATGRLll6pgYALDLDAVLGACEANGTVVEIN
  56 YKG.EWVy12ilMIYADFVVEAIKSGYFSYLAHPDLFGmt9erAEEASKRILKAAEEMNMPIEIN
  57 --T.VVE.....PVEEKTNYYASISEDVDILAHPGFID.....-----KETAENLKENDIFVEIT
  58 FQG.EYY.....--------------------------.....-------------------QIG
  59 ---.---.....--------------------------.....----------------------
  60 ---.---.....--------------------------.....----------------------
  61 ---.VYG.....QAYYERVIRCLESHDVDVLGHPFSPLfg6grLAEMDEKLLDVVEERGVAVELN
  62 GLD.LYE.....KTIYKSS-------------------.....----------------------
  63 ---.---.....-----------LDVEVHILAYAFQPE.....HFSLKPYLQR---------KIT
  64 TEN.GELk12eyIEYAKSICLGIKSGYFDFVAHPDLIFin9enCDKACNLIIDTAKKYDFILEFN
  65 DGR.GGYl12taGIEFRLSMGMVKNAPIDVLAHPGGMSlr7rfPETYFRDLMRATVERRIAIEIN
  66 AWG.FDNp16lyRDYYALVEGAARSGLFDAIGHLDLPKkf7dpDPVYALHALDVVAGQGLALDFN
  67 ---.---.....--------------------------.....----------------------
  68 -LN.QSE.....DEIMKRLINACNNPYIRHIAHPTGRLig6ngYHVNMPKLIETAQKTNTILEIN
  69 ---.---.....--------------------------.....----------------------
  70 ---.---.....--------------------------.....----------------------
  71 -HG.GSE.....AVNRAAL----ENPRVDILNHPAFDR.....SSGLNQVLAKAAAENGVAIGII
  72 DWG.IDLe16vyLEYFNIIEKMAKTGLFDIIGHIDLVKif9ykVFEKIERNIEEISKTGIVIEVS
  73 ---.---.....--------------------------.....----------------------
  74 -HG.GSE.....AVNRAAL----ENPRVDILNHPAFDK.....SSGLNQVLAKAAAENGVAIGIT
  75 --T.LVE.....PVIPGTNHAAVSCPEVDILAHPGLIT.....-----IEDVELARENDVTLEIS
  76 ---.---.....--------------------------.....-----EEHIELTDATYVVFDVE
  77 ---.---.....--------------------------.....------EHRLLADETYVVFDVE
  78 ---.---.....--------------------------.....----------------------
  79 ---.---.....--------------EVHVLCYFYSVEecik.FSEIINKNMTKIKNNKTIF---
  80 ---.---.....--------------------------.....----------------------
  81 ---.---.....--------------------------.....----------------------
  82 ---.---.....--------------------------.....------ETTGFSSKNDKIIEIG
  83 ---.---.....--------------------------.....----------------------
  84 ---.---.....--------------------------.....----------------------
  85 ---.---.....--------------------------.....----------------------
  86 ---.---.....--------------------------.....----------------------
  87 ---.---.....--------------------------.....----------------------
  88 ---.---.....--------------------------.....----------------------
  89 YKN.LME.....IVSTASIEGFYYKPRVD---------.....----------------------
  90 ---.---v89di---------GFLKHNAKVLGYEFDFTyldtl----------------------
  91 ---.---e43knHSEGLIALSACLAGEVPSLILRGDYEkake.---VALFYDSIFGRGNFYLELQ
  92 ---.---t86ds--------------------------.....----------------------


      60        170                     180       190       200       2
      |          |                       |         |         |        
   1 NSSFL.HSRKGSE.....D.....NCR....EVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKI
   2 ---QT.HRRQARG.....R.....LIA....ERLEKAHIPGAW----------------------
   3 ---QT.ERRQARG.....R.....LIA....ERLEKAHIPGAW----------------------
   4 ---QT.ERRNQRA.....Q.....LIA....ERLEKAQIPGAL----------------------
   5 ---QT.ERRNQRA.....Q.....QIA....ERLEKAHIPGAL----------------------
   6 NSSFL.HSRKGSE.....D.....NCR....EVAAAVRDAGGW----------------------
   7 NSSFL.HSRKGSE.....D.....NCR....AVAAAVRDAGGW----------------------
   8 ---QS.EHRYQRA.....Q.....EIS....TRLEKARIVGAW----------------------
   9 NSSFL.HSRKGSE.....D.....NCR....AVAAAVRDAGGWVALGSDSHTAFTLGDFTECRKI
  10 ---QQ.QRRVERA.....E.....LIA....HRLQKATREGVL----------------------
  11 NSSFA.HSRKGSE.....A.....NCR....AIAAAVRDAGGWLALGSDSHIAYALGIFEHCERI
  12 ---QT.ERRQARG.....R.....LIA....ERLEKAHIPGAW----------------------
  13 -----.----LRY.....Q.....RAL....EISDKLAKVGIVDAF-------------------
  14 -----.-TRSGRC.....A.....RAE....DMAEALGKLGIHGAY-------------------
  15 -----.-MKKLRN.....D.....RAR....AILKKLNDLGIKITI-------------------
  16 -----.-VRKGRL.....K.....RLE....AIAAKLEKKGIGGAY-------------------
  17 -----.-VRQGRL.....K.....RLE....AIAAKLEKKGIGGAY-------------------
  18 NSS-F.YVREKSK.....E.....NCI....EILKLCKKYGVYIAMGSDAHYKADIGRCEITQKL
  19 NSTLKgHSRVGSI.....D.....RCY....EIARVAKSLDAYITTGSDAHFCLDIGGLSLASQL
  20 NSSFV.TSRRGSE.....K.....ICP....IIAGKAKEMGVRVAVGSDAHICFDVGRFDEAIRL
  21 ANP--.----QRL.....D.....LNR....EHLEMAHAAGVPIAINTDAHDTKHLDFMSIGVRA
  22 NGSLS.GSREGSY.....D.....NCK....KIAQACKKKGVKVILGTDSHISFTIGNFDKVQKL
  23 ---AA.PLRQATE.....A.....LHR....GRWARAEEIDRR----------------------
  24 ANP--.----NRL.....D.....LNS....EALKKAQEQGVVMAINTDSHTKETFSYMEYGVGV
  25 ANP--.----QRL.....D.....LNR....EHLEMAHAAGVPIAINTDAHDTKHLDFMSIGVRA
  26 ANP--.----NRL.....D.....LSA....KLLKQAQDAGVKVAINTDAHTLEMLEDMETGVAA
  27 SNP--.----FRL.....D.....LDW....RYIKYAKEKGVKFAINPDAHSVDGLEDVKYGVGI
  28 ANP--.----HRL.....D.....LNA....EIVRKY--PNVKLTINTDAHHTNHLDFMNYGVAT
  29 ANP--.----ARL.....D.....LRT....EHLMKANEQGVTLVINTDAHNIEMLDDMKTGVTA
  30 ANP--.----HRL.....D.....LSA....DIVRKY--PNVKLTINTDAHHTNHLDFMNYGVAT
  31 CQP--.----SRL.....D.....LND....ELIFRAKDYELKFCISTDSHSVSDLASMRYGLGQ
  32 ---QQ.DIRKQRL.....E.....QIL....LKLKAA----------------------------
  33 SRP--.----ERR.....D.....PPT....RLLHLARDIGCVFSIDTDAHAPGQLDFLGYGAQR
  34 SRP--.----ERL.....D.....PPR....RLLRRAVAAGVLFSIDTDAHAPGQLDWQIHGCAR
  35 TQR--.------M.....D.....LSP....ENVRKCMEAGVYIGIVTDAHSARQLHLMFLGVGL
  36 SQP--.----SRL.....D.....LND....ELILRAKEYGLKFCISTDSHSMSDLASMRYGLGQ
  37 SRP--.----ERL.....D.....PPR....RLLRRAVAAGVLFSIDTDAHAPGQLDWQIHGCAR
  38 DDN--.-------.....-.....---....----------------------------SIKQLI
  39 DGTEF.YLQKIKE.....E.....AQR....EYLLACLD--------------------------
  40 ---LK.DSRIGRA.....K.....KIV....ANLEKYFNI-------------------------
  41 DGTEF.YLQKTKE.....E.....AQR....EYLLACLD--------------------------
  42 ---LV.QLKKHRE.....G.....RAM....QIIEKFNDIGFTITL-------------------
  43 ---MQ.NYRVWRA.....K.....KIV....ENLDTYFNIKLD----------------------
  44 SRY--.------K.....V.....PDL....EFIKECIRRGIKLSLATDAHRPEDVGKISWSLKM
  45 ARY--.------K.....V.....PDL....EFIRECVKRGIKLSLATDAHRPEDVGKVSWSLKM
  46 SNP--.----LRI.....D.....LRD....THVKMAVDMGCKIAINSDAHSRGALENISWGVIT
  47 SRY--.------R.....V.....PDL....EFVKMCIKRGIKLVFASDAHRPEDVGRVDWSIKV
  48 SSH--.------G.....Y.....LTV....EYVKIAKEEGCKFVINSDAHTPSRVGDFKKGIQI
  49 ARN--.----GHN.....R.....TNG....HVARLALELGAKLVVNTDTHAPEDLITDETALQI
  50 ARN--.----GHN.....R.....TNG....HVARLALEFGATLVVNTDTHAPENLITDETALKI
  51 TRN--.----GHN.....R.....TNG....HVARLALEIGATLVVNTDTHGPGNLITDETALKI
  52 -----.-------.....-.....---....-------------------------DRRDRGRRI
  53 ARK--.----GHC.....L.....GNG....HVAAIAGEVGVPIVIDTDTHAPGDLIDYEMARRI
  54 ARH--.------L.....P.....RDF....TLYQVAIRVGAPITFGSDAHAPEEVGRFKPLQKL
  55 ANA--.----ARL.....D.....LDW....REALRWRER-LKFAINTDAHVPGGLRDARYGVMQ
  56 VNGMR.KNKISYNng6yqY.....PIK....EFWELSKEYNVKRIVGIDAHNPEEMHDLDMGLNF
  57 SRR--.----GHN.....I.....TNG....YVANIAREFGLKTLINTDTHAPEDLIDDEFAKKV
  58 NGS--.-------.....-.....--D....MIGELVEKIGGM----------------------
  59 -NG--.-------.....-.....---....-----------------------------VTLSR
  60 -NS--.----IPI.....D.....FSP....ELWQKALQ--------------------------
  61 SSH--.------K.....S.....PQD....EFLQLCRDRKIAYSIGSDAHSLSGVGEVGWSVEK
  62 -----.-------.....-.....---....----------------------------------
  63 TDR--.-------.....-.....---....----------------------------------
  64 ANGIR.RGKKTYS.....Dge6pyPYE....KFWNKASLAKVKTIINSDCHTPCDLWDN------
  65 SSY--.------L.....V.....DMP....AFLALCEEVNPFVSIGSDAHRLSELGHC------
  66 TAG-W.RKPVAEA.....Y.....PAP....DLVRAAAERGIPFVLGSDAHQPGEVGF-------
  67 -----.-------.....-.....---....----------------------------------
  68 AHP--.----MRL.....D.....LSS....DVLKQY--PDIKLVINTDARAIDQLDLMKYGVGT
  69 -----.-------.....-.....---....----------------------------------
  70 -----.-------.....-.....---....----------------------------------
  71 LRPLL.HSRGSRR.....I.....RLLsdlkSNLELARKYDVSLVLCSDAMSCFDLRSPMEMLAL
  72 TAG-L.RKPVGEI.....Y.....PSK....EIMAMIKKYNIPVVVNSDAHYPEHVGY-------
  73 -----.-------.....-.....---....----------------------------------
  74 LRPLL.HSRGSRR.....I.....RMLsdlkANLELARKYDVPLVLCSDAMSCYDLRSPMETLAF
  75 ARK--.----GHC.....L.....GNG....HVAAIAGEVGVPIVIDTDTHAPGDLIDYEMARRI
  76 TTG--.----LSA.....V.....YDT....----------------------------------
  77 TTG--.----LSA.....V.....YDT....VIELAAVKVKGG----------------------
  78 -----.-------.....-.....---....----------------------------------
  79 -----.----GNQ.....I.....VMD....EKDREIGEMEELLLV-------------------
  80 -----.-------.....-.....---....----------------------------------
  81 -----.-------.....-.....---....----------------------------------
  82 A----.-------.....-.....---....----------------------------------
  83 -----.-------.....-.....---....----------------------------------
  84 -----.-------.....-.....---....----------------------------------
  85 -----.-------.....-.....---....----------------------------------
  86 -----.-------.....-.....---....----------------------------------
  87 -----.-------.....-.....---....----------------------------------
  88 -----.-------.....-.....---....----------------------------------
  89 -----.-------.....-.....---....----------------------------------
  90 -----.-------.....-.....---....----------------------------------
  91 DHGIL.EQK----.....K.....VNR....ELVRMSKETGIPLVATNDVHYLEKKDARAHEVLL
  92 -----.-------.....-.....---....----------------------------------


      10       220        230       240       250       260       270  
      |         |          |         |         |         |         |  
   1 LDAVDFPPERILNVSP.RRLLNFLESRGMAPIAEFADLMYPVDLHMHTVASTHAYSTLSDYIAQA
   2 --------EGALRLAN.GGAVTRGHFARFLVECGKATTMAEV-----------------------
   3 --------EGALRLAN.GGAVTRGHFARFLVECGKAATMADV-----------------------
   4 --------EGAQRLAQ.GGAVTRGHFARFLVECGKASSMADV-----------------------
   5 --------EGAQRLAQ.GGAVTRGHFARFLVECGKASSMADV-----------------------
   6 ----------------.------------------------------------------------
   7 ----------------.------------------------------------------------
   8 --------EGANRLAN.GGQVTRGHFARYLVELGLASNVGQV-----------------------
   9 LDAVNFPEDRILN---.------------------------------------------------
  10 --------EEVQHIAD.GAPITRAHFAKWLVDNGYATNMQQV-----------------------
  11 IAEVNFPQERILN---.------------------------------------------------
  12 --------EGALRLAN.GGAVTRGHFARFLVECGKAATMADV-----------------------
  13 ---------EQAKMLA.TGEVTRAHYARLLVQMGKVSNEGQA-----------------------
  14 --------EGALSYAGnPDMISRTHFARFLVEHGHCRDIAEV-----------------------
  15 --------EDVLEFTS.EKFIGRPHIARAMVKKNYVGSVKEA-----------------------
  16 --------DGALALAAnKEMVSRTHVAEFLIQAGHVKNKQQA-----------------------
  17 --------DGALALAAnKEMVSRTHVAEFLIQAGHVKNKQQA-----------------------
  18 VCEYEFPPELIVNKGL.ESFISFLKLH--------------------------------------
  19 IDEVGINPQRVITHTA.RQFLDFLELRGRQPI---------------------------------
  20 LEDINMPEELVLNTSV.DKVKQYLQ----------------------------------------
  21 ATKAWLDKSAILNT--.------------------------------------------------
  22 LDSVDMPKELIMNTDE.KKIVEYLKAKG-------------------------------------
  23 -------------LAA.KGMPGALEGAR-------------------------------------
  24 ARKGLIRPETVINTWPlERFCAFLR----------------------------------------
  25 ATKAWLGKSAILNT--.------------------------------------------------
  26 ARKGWIQKDNVINTWDiERLLDYI-----------------------------------------
  27 ARKGWLEARDVINTY-.------------------------------------------------
  28 AQKGFVTKDRVINALS.RE----------------------------------------------
  29 ARKGWTETKNVLNA--.------------------------------------------------
  30 AQKGFVTKDRVINALS.R-----------------------------------------------
  31 ARRSWLEKEDIVNTYP.------------------------------------------------
  32 --GVPLEQDAVLRYAD.GGAIGRPHVAKALMDKGYVRSVQEA-----------------------
  33 ALDAEVPADRIVNTWP.------------------------------------------------
  34 AEECGVPPERVVTTW-.------------------------------------------------
  35 ARRGWATPDKVINTF-.------------------------------------------------
  36 ARRGWLEKEDVVNTYP.------------------------------------------------
  37 AEECGVPPERVVTTW-.------------------------------------------------
  38 DAGYDIDFEDYLSYEH.DPSKGGWKTLNFLIDRGICKNIDE------------------------
  39 ----------------.------------------------------------------------
  40 ----KLDYKDVL-AKG.KGVVARPHIAQCIIDAGYPYDWEYI-----------------------
  41 ----------------.------------------------------------------------
  42 --------DEVKQFSE.DGVIARPHIAKAIVKKGYVLDYQTV-----------------------
  43 --------YASILKEA.SNVIARPHIARAILAKGYNYTYEYI-----------------------
  44 FEKAGGSKEDL-----.------------------------------------------------
  45 LEKAGGTKEDL-----.------------------------------------------------
  46 ARRGWAEAGDVLNTMGlRGFMK-------------------------------------------
  47 FEKAGGKKEDL-----.------------------------------------------------
  48 AKEAGLTEEDVIN---.------------------------------------------------
  49 AMGSGLTESGA-----.------------------------------------------------
  50 AMGAGLTESRA-----.------------------------------------------------
  51 AMGAGLTESRVK----.------------------------------------------------
  52 IDRVEARLGVSLPLEP.RPGLGRPHIARAI-----------------------------------
  53 GLGAGLTESGVEEALV.KNPRRLLKRNG-------------------------------------
  54 ARRLGIEPQDV-----.------------------------------------------------
  55 ARKAGLTPAHVVNSLG.------------------------------------------------
  56 AKEHDL----------.------------------------------------------------
  57 GLGAGLTNKELENTLL.HYPKELLK----------------------------------------
  58 --------DKLYDLYY.ETMLKSIKCDLGA-----------------------------------
  59 FLKQDTRPKEV--VYG.EYLNNMLKCIEFYDIFD-------------------------------
  60 --HVGNNPEQLFIDYF.EHQYDLMQRLHPLVIGHF------------------------------
  61 A---------------.------------------------------------------------
  62 ------PKKEVFEMYF.KTMLACLRCHEYID----------------------------------
  63 ----------------.------------------------------------------------
  64 ----------------.------------------------------------------------
  65 ----------------.------------------------------------------------
  66 ----------------.------------------------------------------------
  67 ----------------.----------GHILVLGVKENIEPL-----------------------
  68 AIKGHVKKEQVINTLP.R-----------------------------------------------
  69 --DENLPPDELARDYL.ERTLFVMERVKFH-----------------------------------
  70 ----------------.----------GHILVLGIKEDIEPR-----------------------
  71 AEVCGLEEDEALEAI-.------------------------------------------------
  72 ------EFE-------.------------------------------------------------
  73 ----------------.------------------------------------------------
  74 AEVCGLEEDEALDALS.TV----------------------------------------------
  75 GLGAGLTESGVEEALV.KNPRRLLKRNG-------------------------------------
  76 ----------------.------------------------------------------------
  77 ----------------.------------------------------------------------
  78 ----------------.------------------------------------------------
  79 --SSNFTISEI-----.------------------------------------------------
  80 ----------------.------------------------------------------------
  81 ----------------.------------------------------------------------
  82 ----------------.------------------------------------------------
  83 ----------------.------------------------------------------------
  84 ----------------.------------------------------------------------
  85 ----------------.------------------------------------------------
  86 ----------------.------------------------------------------------
  87 ----------------.------------------------------------------------
  88 ----------------.------------------------------------------------
  89 ----------------.------------------------------------------------
  90 ----------------.------------------------------------------------
  91 CIQTGKTIEDEDRMLF.P---------------------------------------TDEFYLKS
  92 ----------------.------------------------------------------------


           280       290       300       310       320       330       
            |         |         |         |         |         |       
   1 KQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDS
   2 -----------------------------------------------------------------
   3 -----------------------------------------------------------------
   4 -----------------------------------------------------------------
   5 -----------------------------------------------------------------
   6 -----------------------------------------------------------------
   7 -----------------------------------------------------------------
   8 -----------------------------------------------------------------
   9 -----------------------------------------------------------------
  10 -----------------------------------------------------------------
  11 -----------------------------------------------------------------
  12 -----------------------------------------------------------------
  13 -----------------------------------------------------------------
  14 -----------------------------------------------------------------
  15 -----------------------------------------------------------------
  16 -----------------------------------------------------------------
  17 -----------------------------------------------------------------
  18 -----------------------------------------------------------------
  19 -----------------------------------------------------------------
  20 -----------------------------------------------------------------
  21 -----------------------------------------------------------------
  22 -----------------------------------------------------------------
  23 --------AIQQALGDSGNAPARPHFAEFLVQGGWVKDRA------------------------D
  24 -----------------------------------------------------------------
  25 -----------------------------------------------------------------
  26 -----------------------------------------------------------------
  27 -----------------------------------------------------------------
  28 -----------------------------------------------------------------
  29 -----------------------------------------------------------------
  30 -----------------------------------------------------------------
  31 -----------------------------------------------------------------
  32 -----------------------------------------------------------------
  33 -----------------------------------------------------------------
  34 -----------------------------------------------------------------
  35 -----------------------------------------------------------------
  36 -----------------------------------------------------------------
  37 -----------------------------------------------------------------
  38 -----------------------------------------------------------------
  39 ----------------------------------------VVQNFENYNSFGHLDYVARYGPYTD
  40 -----------------------------------------------------------------
  41 ----------------------------------------VVQNFETYNSFGHLDYVARYGPYTD
  42 -----------------------------------------------------------------
  43 -----------------------------------------------------------------
  44 -----------------------------------------------------------------
  45 -----------------------------------------------------------------
  46 -----------------------------------------------------------------
  47 -----------------------------------------------------------------
  48 -----------------------------------------------------------------
  49 -----------------------------------------------------------------
  50 -----------------------------------------------------------------
  51 -----------------------------------------------------------------
  52 ----------------------------------------------------TAHPDTDYDTMDA
  53 -----------------------------------------------------------------
  54 -----------------------------------------------------------------
  55 -----------------------------------------------------------------
  56 -----------------------------------------------------------------
  57 -----------------------------------------------------------------
  58 ------------------------------FKPKRIGHPTLVRKYKADFPNEKYNIKL-------
  59 -------------------------------------------------TLGHIDYPCRYSTYDD
  60 --DLICLFAPEDAKEVFKNSKSVWELIQRNI----------------------------------
  61 -----------------------------------------------------------------
  62 -------------------------------------------------SLAHIDYISRYAAYHD
  63 -----------------------------------------------------------------
  64 -----------------------------------------------------------------
  65 -----------------------------------------------------------------
  66 -----------------------------------------------------------------
  67 -----------------------------------------------------------------
  68 -----------------------------------------------------------------
  69 -------------------------------------------------TLAHLDYPARYAKADF
  70 -----------------------------------------------------------------
  71 -----------------------------------------------------------------
  72 -----------------------------------------------------------------
  73 -----------------------------------------------------------------
  74 -----------------------------------------------------------------
  75 -----------------------------------------------------------------
  76 -----------------------------------------------------------------
  77 -----------------------------------------------------------------
  78 -----------------------------------------------------------------
  79 -----------------------------------------------------------------
  80 -----------------------------------------------------------------
  81 -----------------------------------------------------------------
  82 -----------------------------------------------------------------
  83 -----------------------------------------------------------------
  84 -----------------------------------------------------------------
  85 -----------------------------------------------------------------
  86 -----------------------------------------------------------------
  87 -----------------------------------------------------------------
  88 -----------------------------------------------------------------
  89 -----------------------------------------------------------------
  90 -----------------------------------------------------------------
  91 PEEMEELFACCKEAIENTEKIAEMCNIEFEFNKTKLPKYDLPEGVDSYEYLRNLCYEGLYKRYKS
  92 -----------------------------------------------------------------


      340       350        360       370       380         390        4
       |         |          |         |         |           |         
   1 LDLIIAGFHEPVFAPHD.KATNTQAMIATIASGNVHIISHPGNPKY..EIDVKAVAE.AAAKHQV
   2 -FKKYLARGKTGYVPPQ.WCTIEQAIDVIHHSGGKAVLAHPGRYDLsaKWLKRLVAH.FADHHGD
   3 -FKKYLARGKTGYVPPQ.WCTIEQAIDVIHHSGGKAVLAHPGRYDLsaKWLKRLVAH.FADHHGD
   4 -FKKYLARGKTGYVPPQ.WCTIEQAIDVIHHSGGKAVLAHPGRYNLsaKWLKRLVAH.FAEHHGD
   5 -FKKYLARGKTGYVPPQ.WCTIEQAIDVIHHSGGKAVLAHPGRYNLsaKWLKRLVAH.FAEHDGD
   6 -----------------.----------------------------..---------.-------
   7 -----------------.----------------------------..---------.-------
   8 -FKKYLAKGKTGYVPAQ.WCTIEQAIDAIKQSGGQAVLAHPGRYDLtaKWLKRLLAH.FAEHGGD
   9 -----------------.----------------------------..---------.-------
  10 -FKKYLTRDNPGYVPPN.WCSMSEAVSAIHAAGGQAVLAHPGRYDLtaKWLKRLMTA.FVEAGGD
  11 -----------------.----------------------------..---------.-------
  12 -FKKYLARGKTGYVPPQ.WCTIEQAIDVIHHSGGKAVLAHPGRYDLsaKWLKRLVAH.FADHHGD
  13 -FKKYLSQGKSCYVKAQ.WCDIPTAIEVIHQTGGLAVLAHPLRYTLtnKWVKKLIAD.FAQWGGD
  14 -FDRYLGEGKPGFVPHR.WSRLADAIGWIRGAGGVAVMAHPGRYTLtlLEHGALFDE.FKDLGGE
  15 -FEKYIGVGGPAYVERY.RITPMEAIDLILENGGVPVLAHPGLLS-..--DDSVIEE.LVKRNLV
  16 -FTKYLGDGKSCAVRHE.WATLEDCVSAVNGAGGMAVIAHPMRYDLsaTAKRNLFEE.FKNLGGA
  17 -FIKYLGDGKSCAVRHE.WATLEDCVSAVNGAGGMAVIAHPMRYDLsaTAKRNLFEE.FKNLGGA
  18 -----------------.----------------------------..---------.-------
  19 -----------------.----------------------------..---------.-------
  20 -----------------.----------------------------..---------.-------
  21 -----------------.----------------------------..---------.-------
  22 -----------------.----------------------------..---------.-------
  23 AFRKWLGAGKLGDVKQH.WPTLEEVVGCLREARAWISLAHPYHYDFtrTKRRRLVAD.FLQAGGH
  24 -----------------.----------------------------..---------.-------
  25 -----------------.----------------------------..---------.-------
  26 -----------------.----------------------------..---------.-------
  27 -----------------.----------------------------..---------.-------
  28 -----------------.----------------------------..---------.-------
  29 -----------------.----------------------------..---------.-------
  30 -----------------.----------------------------..---------.-------
  31 -----------------.----------------------------..---------.-------
  32 -FEHYLAEGRPCYVKRQeYISVEQAIAWIHQAGGVAIVAHPGYYD-..-LDDQLIGW.VREYGLD
  33 -----------------.----------------------------..---------.-------
  34 -----------------.----------------------------..---------.-------
  35 -----------------.----------------------------..---------.-------
  36 -----------------.----------------------------..---------.-------
  37 -----------------.----------------------------..---------.-------
  38 -FFNKIFVGERALKYPD.FPHPKEVIETIKKANGIVVLAHPKYGKS..QFKLDEMLElFKNWGVD
  39 KSIKFAENREILF----.----------------------------..-----EILR.ALASKEK
  40 -FDNFIGNDSPAYVPNK.KISVEEGINILKANNAITVLAHPKLIK-..RVPVKEVME.FPFDGIE
  41 KSITFAENREILF----.----------------------------..-----EILR.ALASKGK
  42 -FDEYLADGKPCAIDKM.ILTPEEGIKLIHEAGGKAILAHPVYLE-..---DTLVRE.LLALDFD
  43 -FNNILNKESPAYIPNK.KVSVEEGIKLLKAANAVVVLAHPVLIK-..---KTPIED.FLKLDFD
  44 -----------------.----------------------------..---------.-------
  45 -----------------.----------------------------..---------.-------
  46 -----------------.----------------------------..---------.-------
  47 -----------------.----------------------------..---------.-------
  48 -----------------.----------------------------..---------.-------
  49 -----------------.----------------------------..---------.-------
  50 -----------------.----------------------------..---------.-------
  51 -----------------.----------------------------..---------.-------
  52 VFDSLIGNDGPCFVARD.VPDFETGVDLLTDACGLVGLAHPLRYD-..---DPQHAL.ALCAALD
  53 -----------------.----------------------------..---------.-------
  54 -----------------.----------------------------..---------.-------
  55 -----------------.----------------------------..---------.-------
  56 -----------------.----------------------------..---------.-------
  57 -----------------.----------------------------..---------.-------
  58 -----------------.----------------------------..---LESILK.EMKKGNY
  59 KEMTLTDF---------.----------------------------..KPKFQSIFK.TLIDKNK
  60 -----------------.----------------------------..--------K.YAVSYGG
  61 -----------------.----------------------------..---------.-------
  62 GEIYYNEY---------.----------------------------..SDYIDEVLK.FIVDREI
  63 -----------------.EYQAGNVIEAIHAAGGIAVLAHPARYR-..KSHFDLIPA.AAGYGID
  64 -----------------.----------------------------..---------.-------
  65 -----------------.----------------------------..---------.-------
  66 -----------------.----------------------------..---------.-------
  67 -----------------.-LSPEETILKARKLGGTVIIPHPFKRS-..---SHGIGS.FEGLDID
  68 -----------------.----------------------------..---------.-------
  69 KAN--------------.----------------------------..RDLIEKILV.FLVKNEK
  70 -----------------.-LSPEETIRRARKLGGTVIIPHPFKSS-..---SHGIGS.FEGLDTD
  71 -----------------.----------------------------..---------.-------
  72 -----------------.----------------------------..---------.-------
  73 -----------------.----EELREWAVERGCVTIAAHPGYSRY..HGIPLDAIR.RAASLFD
  74 -----------------.----------------------------..---------.-------
  75 -----------------.----------------------------..---------.-------
  76 -----------------.----------------------------..---------.-------
  77 -----------------.----------------------------..---------.-------
  78 -----------------.----------------------------..---------.-------
  79 -----------------.--------FQYIEGRGAAVPAHVNRGSY..SIISNLGFI.PNIKSLS
  80 -----------------.----------------------------..---------.-------
  81 -----------------.----------------------------..---------.-------
  82 -----------------.----------------------------..---------.-------
  83 -----------------.----------------------------..---------.-------
  84 -----------------.----------------------------..---------.-------
  85 -----------------.----------------------------..---------.-------
  86 -----------------.----------------------------..---------.-------
  87 -----------------.----------------------------..---------.-------
  88 -----------------.----------------------------..---------.-------
  89 -----------------.----------------------------..---------.-------
  90 -----------------.----------------------------..---------.-------
  91 PSQEV------------.----------------------------..---------.-------
  92 -----------------.-----------------IIVAHNANFDY..RFLRL----.-------


      00       410        420       430        440          450       4
      |         |          |         |          |            |        
   1 ALEINNSSFLHS.RKGSEDNCREVAAAVRDAGG.WVALGSDSHTA..FTMGE.FEECLKILDAVD
   2 AMEVA------Q.CQQSPNERTQLATLARQHHL.WASLGSDFHQP..CPWIE.LGRKLWLPAGVE
   3 AMEVA------Q.CQQSPNERTQLATLARQHHL.WASLGSDFHQP..CPWIE.LGRKLWLPAGVE
   4 AMEVA------Q.CQQSPNERTQLAALARQHHL.WASQGSDFHQP..CPWIE.LGRKLWLPAGVE
   5 AMEVA------Q.CQQSPNERTQLATLARQHHL.WASQGSDFHQP..CPWIE.LGRKLWLPAGVE
   6 ------------.--------------------.-VALGSDSHTA..FTMGE.FEECLKILDAVD
   7 ------------.--------------------.-VALGSDSHTA..FTMGE.FEECLKILDAVD
   8 AMEVA------Q.CQQAPHERALLGQYARDYHL.LASQGSDFHQP..CSWIE.LGRKLWLPAGVE
   9 ------------.--------------------.-----------..-----.------------
  10 AMEVA------Q.PQQSPQEKRTLGDYAMEYQL.LASQGSDFHYP..SPWME.LGRNLWLPAGVE
  11 ------------.--------------------.-----------..-----.------------
  12 AMEVA------Q.CQQSPNERTQLATLARQHHL.WASLGSDFHQP..CPWIE.LGRKLWLPAGVE
  13 AIEVA------G.CGQAPEQRLLLAQWATEFGL.LSSVGSDFHFP..CGWVE.LGKSLLLPANCV
  14 GVEVV------T.GSHTPDQYACYADVARRYGL.LASRGSDFHGPg.EGRVE.LGELPPLPDNLT
  15 GIEVF------H.SKHTERDVEKYFEKAKQYNL.IITGGSDFHGI..EVDG-.--RDLLGTVKLD
  16 GIEVH------S.GNCCKNDRLNYALLAERFGM.LASAGSDFHRLndFSGGI.LGACPELPENCK
  17 GIEVH------S.GNCCKNDRLNYALLAERFGM.LASAGSDFHRLndFSGGI.LGACPELPENCR
  18 ------------.--------------------.-----------..-----.------------
  19 ------------.--------------------.-----------..-----.------------
  20 ------------.--------------------.-----------..-----.------------
  21 ------------.--------------------.-----------..-----.------------
  22 ------------.--------------------.-----------..-----.------------
  23 AIEVV------N.GVQPAEQVGTLSILAREFGL.MVTAGSDFHAP..GDWSE.LGMYRAVPEDLP
  24 ------------.--------------------.-----------..-----.------------
  25 ------------.--------------------.-----------..-----.------------
  26 ------------.--------------------.-----------..-----.------------
  27 ------------.--------------------.-----------..-----.------------
  28 ------------.--------------------.-----------..-----.------------
  29 ------------.--------------------.-----------..-----.------------
  30 ------------.--------------------.-----------..-----.------------
  31 ------------.--------------------.-----------..-----.------------
  32 GIEVYHRDHSRE.VVAHYEQLCKRMEAETGRRL.LRTGGSDFHH-..-----.------------
  33 ------------.--------------------.-----------..-----.------------
  34 ------------.--------------------.-----------..-----.------------
  35 ------------.--------------------.-----------..-----.------------
  36 ------------.--------------------.-----------..-----.------------
  37 ------------.--------------------.-----------..-----.------------
  38 GIECY------H.PHHDEDTIKYLVDYCTKNNL.IITGGSDYHG-..-----.------------
  39 ALEINTRLF--D.DPKTEQFYSDLLINFKKLGGkFITLGTDSHIA..KRDW-.------------
  40 AI---------Y.YQNTKKDNDFFISYAVHHDL.LITCGSDFHGD..-----.------------
  41 ALEINTRLF--D.DPKTGQFYSDLLINFKRLGGkFITLGTDSHIA..KRDW-.------------
  42 GIEVW------H.RNHDETDQEKYKMLATEFAL.IKTGGSDFHTD..E----.------------
  43 GIEAI------Y.PMNSESDTERFLSLAKIYNK.LVTAGSDFHTD..-----.------------
  44 ------------.--------------------.-----------..-----.------------
  45 ------------.--------------------.-----------..-----.------------
  46 ------------.--------------------.-----------..-----.------------
  47 ------------.--------------------.-----------..-----.------------
  48 ------------.--------------------.-----------..-----.------------
  49 ------------.--------------------.-----------..-----.------------
  50 ------------.--------------------.-----------..-----.------------
  51 ------------.--------------------.-----------..-----.------------
  52 AVEAHYPYDRPV.GTAPDDGAALVADAIDTHDL.IPTGGTDAH--..-----.------------
  53 ------------.--------------------.-----------..-----.------------
  54 ------------.--------------------.-----------..-----.------------
  55 ------------.--------------------.-----------..-----.------------
  56 ------------.--------------------.-----------..-----.------------
  57 ------------.--------------------.-----------..-----.------------
  58 EIDLNTSGLRRE.KCGEVHPQGIFLDLCLKYNI.PMVLGSDSHSS..KYVG-.------------
  59 VLELNTTRL--D.DETSFKNMVEIYSYYRELGGkYITLGSDSHKI..EHVG-.------------
  60 IFEINTSAFRKG.WKTAYPQQR-LLELMVEQGA.QLTLSDDSHGP..HQVG-.------------
  61 ------------.--------------------.-----------..-----.------------
  62 VIEINTRRL--N.KKEVCENLMPIYKRYSELGGrFVTIGSDSHYK..DSIG-.------------
  63 GVETYYAYNNPNpWKPSVIESEQIQNLAKEYGI.FNTCGTDTHGL..SL---.------------
  64 ------------.--------------------.-----------..-----.------------
  65 ------------.--------------------.-----------..-----.------------
  66 ------------.--------------------.-----------..-----.------------
  67 AVEVFNSRCLFN.SAN-----RKALEEAKRLGI.PGVAGSDSHIP..EMVG-.------------
  68 ------------.--------------------.-----------..-----.------------
  69 ALEINTAGLFKH.GKPNPD--YWIVEMYYDLGGrVVTIGSDAHES..QHIGRgIEEVMRELKKFN
  70 AVEVFNSRCLFN.GAN-----RKALVEAERLGI.PAVAGSDSHIP..EMVG-.------------
  71 ------------.--------------------.-----------..-----.------------
  72 ------------.--------------------.-----------..-----.------------
  73 AIEVW------N.AYTPPHFNFMAIRLAEDLNH.TPVSGSDAHVP..SMVG-.----------VA
  74 ------------.--------------------.-----------..-----.------------
  75 ------------.--------------------.-----------..-----.------------
  76 ------------.--------------------.-----------..-----.------------
  77 ------------.--------------------.-----------..-----.------------
  78 ------------.--------------------.-----------..-----.------------
  79 TIEISKSTDKKV.FLKEHPECK---------KY.RIISSSDAHHL..GYISE.REEFL-------
  80 ------------.--------------------.-----------..-----.------------
  81 ------------.--------------------.-----------..-----.------------
  82 ------------.--------------------.-----------..-----.------------
  83 ------------.--------------------.-----------..-----.------------
  84 ------------.--------------------.-----------..-----.------------
  85 ------------.--------------------.-----------..-----.------------
  86 ------------.--------------------.-----------..-----.------------
  87 ------------.--------------------.-----------..-----.------------
  88 ------------.--------------------.-----------..-----.------------
  89 ------------.--------------------.-----------..-----.------------
  90 ------------.--------------------.-----------..-----.------------
  91 ------------.--------------------.-----------..-----.------------
  92 ------------.--------------------.-----------..-----.------------


      60       470       480       490
      |         |         |         |
   1 FPPERILNVSPRRLLNFLESRGMAPIAEFADL
   2 GVWQAWEQ------------------------
   3 GVWQTWEQ------------------------
   4 GVWQLWEQ------------------------
   5 GVWQLWEQ------------------------
   6 FPPERILNVSPRRLLNFLESRGMAPIAEFADL
   7 FPPERILNVSPRRLLNFLESRGMAPIAEFADL
   8 PVWRDWPTE-----------------------
   9 --------VSPQRLLAFLESRGMAPVPEFAEL
  10 PVWKDWGLSPSNRVERL---------------
  11 --------VSPRRLLDYLEQRGRPAIPELAEL
  12 GVWQTWEQ------------------------
  13 PIWT----------------------------
  14 PVWSRW--------------------------
  15 YKNVEILKSKARNLDRNLKT------------
  16 PVWEH---------------------------
  17 PVWA----------------------------
  18 --------------------------------
  19 --------------------------------
  20 --------------------------------
  21 --------------------------------
  22 --------------------------------
  23 AMWPRF--------------------------
  24 --------------------------------
  25 --------------------------------
  26 --------------------------------
  27 --------------------------------
  28 --------------------------------
  29 --------------------------------
  30 --------------------------------
  31 --------------------------------
  32 --------------------------------
  33 --------------------------------
  34 --------------------------------
  35 --------------------------------
  36 --------------------------------
  37 --------------------------------
  38 --------------------------------
  39 --------LSIHKARTLIKKAGFHELATFSGM
  40 --------------------------------
  41 --------LSIHKARTLIKKAGFRELATFSGM
  42 --------------------------------
  43 --------------------------------
  44 --------------------------------
  45 --------------------------------
  46 --------------------------------
  47 --------------------------------
  48 --------------------------------
  49 --------------------------------
  50 --------------------------------
  51 --------------------------------
  52 --------------------------------
  53 --------------------------------
  54 --------------------------------
  55 --------------------------------
  56 --------------------------------
  57 --------------------------------
  58 --------VEFEKVANM---------------
  59 --------RNFERLYKFLEETKLTPC------
  60 --------LNYHLAKSYLDKCGITS-------
  61 --------------------------------
  62 --------LNFKNALKMAENCNLKPV------
  63 --------------------------------
  64 --------------------------------
  65 --------------------------------
  66 --------------------------------
  67 --------------------------------
  68 --------------------------------
  69 FE------------------------------
  70 --------------------------------
  71 --------------------------------
  72 --------------------------------
  73 PALVDSDNESAEGVVEAIAKGRARPTIGFP--
  74 --------------------------------
  75 --------------------------------
  76 --------------------------------
  77 --------------------------------
  78 --------------------------------
  79 --------------------------------
  80 --------------------------------
  81 --------------------------------
  82 --------------------------------
  83 --------------------------------
  84 --------------------------------
  85 --------------------------------
  86 --------------------------------
  87 --------------------------------
  88 --------------------------------
  89 --------------------------------
  90 --------------------------------
  91 --------------------------------
  92 --------------------------------