Sequence numbers correspond to the following labels:

1. • T0147 ycdX, E.coli
2. • gi|16128997|ref|NP_415552.1|_1:245 (NC_000913) orf, hypothetical protein [Escherichia coli K12]
   • gi|2495593sp|P75914|YCDX_ECOLI Hypothetical protein ycdX precursor
   • gi|7467104|pir||G64845 ycdX protein - Escherichia coli
   • gi|1787271|gb|AAC74118.1| (AE000205) orf, hypothetical protein [Escherichia coli K12]
   • gi|4062598|dbj|BAA35815.1| (D90740) ORF_ID:o231#2 [Escherichia coli]
   • gi|4062607|dbj|BAA35824.1| (D90741) ORF_ID:o231#2 [Escherichia coli]
3. • gi|15801151|ref|NP_287168.1|_1:245 (NC_002655) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
   • gi|15830665|ref|NP_309438.1| (NC_002695) hypothetical protein [Escherichia coli O157:H7]
   • gi|12514563|gb|AAG55780.1|AE005314_8 (AE005314) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
   • gi|13360871|dbj|BAB34834.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]
4. • gi|16122276|ref|NP_405589.1|_1:244 (NC_003143) conserved hypothetical protein [Yersinia pestis]
   • gi|15980048|emb|CAC90849.1| (AJ414151) conserved hypothetical protein [Yersinia pestis]
5. • gi|16760013|ref|NP_455630.1|_1:244 (NC_003198) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
   • gi|16764492|ref|NP_460107.1| (NC_003197) putative Histidinol phosphatase and related hydrolases of the PHP family [Salmonella typhimurium LT2]
   • gi|16419651|gb|AAL20066.1| (AE008749) putative Histidinol phosphatase and related hydrolases of the PHP family [Salmonella typhimurium LT2]
   • gi|16502307|emb|CAD08260.1| (AL627269) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
6. • gi|21402596|ref|NP_658581.1|_335:569 (NC_003995) POLXc, DNA polymerase X family [Bacillus anthracis A2012] [Bacillus anthracis str. A2012]
7. • gi|20808367|ref|NP_623538.1|_9:241 (NC_003869) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
   • gi|20516977|gb|AAM25142.1| (AE013147) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
8. • gi|15615669|ref|NP_243973.1|_333:567 (NC_002570) DNA-dependent DNA polymerase beta chain [Bacillus halodurans]
   • gi|10175729|dbj|BAB06826.1| (AP001517) DNA-dependent DNA polymerase beta chain [Bacillus halodurans]
9. • gi|15924133|ref|NP_371667.1|_331:565 (NC_002758) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus Mu50]
   • gi|15926727|ref|NP_374260.1| (NC_002745) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus N315]
   • gi|13700943|dbj|BAB42239.1| (AP003132) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus N315]
   • gi|14246913|dbj|BAB57305.1| (AP003361) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus Mu50]
10. • gi|16800263|ref|NP_470531.1|_334:568 (NC_003212) similar to DNA polymerase beta, to B. subtilis YshC protein [Listeria innocua]
    • gi|16413653|emb|CAC96425.1| (AL596167) similar to DNA polymerase beta, to B. subtilis YshC protein [Listeria innocua]
11. • gi|16079911|ref|NP_390737.1|_333:567 (NC_000964) similar to DNA polymerase beta [Bacillus subtilis]
    • gi|7430180|pir||C69985 probable DNA-dependent DNA polymerase beta chain yshC - Bacillus subtilis
    • gi|1770035|emb|CAA99568.1| (Z75208) hypothetical protein [Bacillus subtilis]
    • gi|2635324|emb|CAB14819.1| (Z99118) similar to DNA polymerase beta [Bacillus subtilis]
12. • gi|16803271|ref|NP_464756.1|_334:568 (NC_003210) similar to DNA polymerase beta, to B. subtilis YshC protein [Listeria monocytogenes EGD-e]
    • gi|16410647|emb|CAC99309.1| (AL591978) similar to DNA polymerase beta, to B. subtilis YshC protein [Listeria monocytogenes]
13. • gi|21282755|ref|NP_645843.1|_331:564 (NC_003923) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus MW2]
    • gi|21204193|dbj|BAB94891.1| (AP004825) DNA-dependent DNA polymerase beta chain [Staphylococcus aureus subsp. aureus MW2]
14. • gi|15893800|ref|NP_347149.1|_3:235 (NC_003030) PHP family protein [Clostridium acetobutylicum]
    • gi|15023371|gb|AAK78489.1|AE007565_8 (AE007565) PHP family protein [Clostridium acetobutylicum]
15. • gi|21227996|ref|NP_633918.1|_347:578 (NC_003901) DNA polymerase beta [Methanosarcina mazei Goe1]
    • gi|20906424|gb|AAM31590.1| (AE013426) DNA polymerase beta [Methanosarcina mazei Goe1]
16. • gi|2499170sp|Q44408|YOR4_ANATH_9:240 Hypothetical 27.7 kDa protein in XYNA-ALFA intergenic region (ORF4)
    • gi|1208897|emb|CAA93629.1| (Z69782) hypothetical protein [Anaerocellum thermophilum]
17. • gi|21219312|ref|NP_625091.1|_125:366 (NC_003888) conserved hypothetical protein [Streptomyces coelicolor A3(2)]
    • gi|11071281|emb|CAC14354.1| (AL445945) conserved hypothetical protein [Streptomyces coelicolor A3(2)]
18. • gi|20808870|ref|NP_624041.1|_334:565 (NC_003869) DNA polymerase IV (family X) [Thermoanaerobacter tengcongensis]
    • gi|20517526|gb|AAM25645.1| (AE013193) DNA polymerase IV (family X) [Thermoanaerobacter tengcongensis]
19. • gi|15606601|ref|NP_213981.1|_341:575 (NC_000918) DNA polymerase beta family [Aquifex aeolicus]
    • gi|7430181|pir||F70423 DNA polymerase beta family - Aquifex aeolicus
    • gi|2983818|gb|AAC07374.1| (AE000739) DNA polymerase beta family [Aquifex aeolicus]
20. • gi|15601648|ref|NP_233279.1|_4:246 (NC_002506) conserved hypothetical protein [Vibrio cholerae]
    • gi|11354819|pir||G82403 conserved hypothetical protein VCA0894 [imported] - Vibrio cholerae (group O1 strain N16961)
    • gi|9658328|gb|AAF96791.1| (AE004417) conserved hypothetical protein [Vibrio cholerae]
21. • gi|1518394|emb|CAA94729.1|_96:337 (Z70724) ORF1 [Streptomyces lividans]
22. • gi|20089612|ref|NP_615687.1|_351:582 (NC_003552) DNA-directed DNA polymerase, family X [Methanosarcina acetivorans str. C2A]
    • gi|19914532|gb|AAM04167.1| (AE010734) DNA-directed DNA polymerase, family X [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
23. • gi|16760159|ref|NP_455776.1|_12:230 (NC_003198) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
    • gi|16502453|emb|CAD08410.1| (AL627269) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
24. • gi|15801913|ref|NP_287933.1|_8:226 (NC_002655) putative enzymes [Escherichia coli O157:H7 EDL933]
    • gi|15831092|ref|NP_309865.1| (NC_002695) putative enzymes [Escherichia coli O157:H7]
    • gi|12515531|gb|AAG56549.1|AE005380_8 (AE005380) putative enzymes [Escherichia coli O157:H7 EDL933]
    • gi|13361303|dbj|BAB35261.1| (AP002556) putative enzymes [Escherichia coli O157:H7]
25. • gi|16129227|ref|NP_415782.1|_8:226 (NC_000913) putative enzymes [Escherichia coli K12]
    • gi|3025078sp|P77766|TRPH_ECOLI Protein trpH
    • gi|7449461|pir||E64874 probable metal-dependent phosphoesterase yciV - Escherichia coli
    • gi|1742058|dbj|BAA14800.1| (D90764) ORF_ID:o253#3; similar to [SwissProt Accession Number P44176] [Escherichia coli]
    • gi|1742074|dbj|BAA14815.1| (D90765) ORF_ID:o253#3; similar to [SwissProt Accession Number P44176] [Escherichia coli]
    • gi|1787520|gb|AAC74348.1| (AE000224) putative enzymes [Escherichia coli K12]
26. • gi|16765065|ref|NP_460680.1|_12:230 (NC_003197) trpR controlled transcriptional unit in the 5' upstream region of the trp operon [Salmonella typhimurium LT2]
    • gi|20141852sp|O54453|TRPH_SALTY Protein trpH
    • gi|16420251|gb|AAL20639.1| (AE008776) trpR controlled transcriptional unit in the 5' upstream region of the trp operon [Salmonella typhimurium LT2]
27. • gi|15610992|ref|NP_218373.1|_95:330 (NC_000962) hypothetical protein Rv3856c [Mycobacterium tuberculosis H37Rv]
    • gi|15843487|ref|NP_338524.1| (NC_002755) conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
    • gi|7477795|pir||E70655 hypothetical protein Rv3856c - Mycobacterium tuberculosis (strain H37RV)
    • gi|1781100|emb|CAB06234.1| (Z83864) hypothetical protein Rv3856c [Mycobacterium tuberculosis H37Rv]
    • gi|13883860|gb|AAK48338.1| (AE007189) conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
28. • gi|16122439|ref|NP_405752.1|_15:234 (NC_003143) conserved hypothetical protein [Yersinia pestis]
    • gi|15980211|emb|CAC91017.1| (AJ414151) conserved hypothetical protein [Yersinia pestis]
29. • gi|15805494|ref|NP_294190.1|_326:558 (NC_001263) conserved hypothetical protein [Deinococcus radiodurans]
    • gi|7471437|pir||C75515 conserved hypothetical protein - Deinococcus radiodurans (strain R1)
    • gi|6458154|gb|AAF10047.1|AE001906_3 (AE001906) conserved hypothetical protein [Deinococcus radiodurans]
30. • gi|15641190|ref|NP_230822.1|_1:219 (NC_002505) conserved hypothetical protein [Vibrio cholerae]
    • gi|11279907|pir||D82233 conserved hypothetical protein VC1177 [imported] - Vibrio cholerae (group O1 strain N16961)
    • gi|9655653|gb|AAF94336.1| (AE004197) conserved hypothetical protein [Vibrio cholerae]
31. • gi|14521038|ref|NP_126513.1|_2:209 (NC_000868) hypothetical protein [Pyrococcus abyssi]
    • gi|7517882|pir||G75128 hypothetical protein PAB0560 - Pyrococcus abyssi (strain Orsay)
    • gi|5458255|emb|CAB49744.1| (AJ248285) hypothetical protein [Pyrococcus abyssi]
32. • gi|17545859|ref|NP_519261.1|_9:228 (NC_003295) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
    • gi|17428153|emb|CAD14842.1| (AL646062) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
33. • gi|14591128|ref|NP_143203.1|_2:209 (NC_000961) hypothetical protein [Pyrococcus horikoshii]
    • gi|7519083|pir||F71002 hypothetical protein PH1316 - Pyrococcus horikoshii
    • gi|3257739|dbj|BAA30422.1| (AP000006) 216aa long hypothetical protein [Pyrococcus horikoshii]
34. • gi|15669485|ref|NP_248295.1|_1:215 (NC_000909) conserved hypothetical protein [Methanococcus jannaschii]
    • gi|2128772|pir||F64461 hypothetical protein MJ1295 - Methanococcus jannaschii
    • gi|1591933|gb|AAB99302.1| (U67570) conserved hypothetical protein [Methanococcus jannaschii] [Methanocaldococcus jannaschii]
35. • gi|18977862|ref|NP_579219.1|_1:208 (NC_003413) hypothetical protein [Pyrococcus furiosus DSM 3638]
    • gi|18893618|gb|AAL81614.1| (AE010250) hypothetical protein [Pyrococcus furiosus DSM 3638]
36. • gi|15677660|ref|NP_274821.1|_2:217 (NC_003112) conserved hypothetical protein [Neisseria meningitidis MC58]
    • gi|11279909|pir||A81040 conserved hypothetical protein NMB1824 [imported] - Neisseria meningitidis (group B strain MD58)
    • gi|7227077|gb|AAF42159.1| (AE002531) conserved hypothetical protein [Neisseria meningitidis MC58]
37. • gi|20090153|ref|NP_616228.1|_3:210 (NC_003552) conserved hypothetical protein [Methanosarcina acetivorans str. C2A]
    • gi|19915137|gb|AAM04708.1| (AE010798) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
38. • gi|20808251|ref|NP_623422.1|_2:240 (NC_003869) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
    • gi|20516849|gb|AAM25026.1| (AE013135) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
39. • gi|15793623|ref|NP_283445.1|_2:217 (NC_003116) hypothetical protein NMA0635 [Neisseria meningitidis Z2491]
    • gi|11279908|pir||E81983 hypothetical protein NMA0635 [imported] - Neisseria meningitidis (group A strain Z2491)
    • gi|7379368|emb|CAB83925.1| (AL162753) hypothetical protein NMA0635 [Neisseria meningitidis Z2491]
40. • gi|7451271|pir||C69176_8:225 conserved hypothetical protein MTH576 - Methanobacterium thermoautotrophicum (strain Delta H)
41. • gi|20093609|ref|NP_613456.1|_2:228 (NC_003551) Predicted phosphatase of the PHP family [Methanopyrus kandleri AV19]
    • gi|19886471|gb|AAM01386.1| (AE010316) Predicted phosphatase of the PHP family [Methanopyrus kandleri AV19]
42. • gi|20807816|ref|NP_622987.1|_25:223 (NC_003869) predicted metal-dependent phosphoesterases (PHP family) [Thermoanaerobacter tengcongensis]
    • gi|20516375|gb|AAM24591.1| (AE013096) predicted metal-dependent phosphoesterases (PHP family) [Thermoanaerobacter tengcongensis]
43. • gi|15602481|ref|NP_245553.1|_3:220 (NC_002663) unknown [Pasteurella multocida]
    • gi|12720889|gb|AAK02700.1| (AE006098) unknown [Pasteurella multocida]
44. • gi|11498832|ref|NP_070061.1|_2:199 (NC_000917) conserved hypothetical protein [Archaeoglobus fulgidus]
    • gi|7483103|pir||H69403 conserved hypothetical protein AF1233 - Archaeoglobus fulgidus
    • gi|2649349|gb|AAB90011.1| (AE001019) conserved hypothetical protein [Archaeoglobus fulgidus]
45. • gi|15678578|ref|NP_275693.1|_333:547 (NC_000916) DNA-dependent DNA polymerase family X [Methanothermobacter thermautotrophicus] [Methanothermobacter thermautotrophicus str. Delta H]
    • gi|7430182|pir||G69172 DNA-dependent DNA polymerase family X - Methanobacterium thermoautotrophicum (strain Delta H)
    • gi|2621626|gb|AAB85056.1| (AE000838) DNA-dependent DNA polymerase family X [Methanothermobacter thermautotrophicus str. Delta H]
46. • gi|18309954|ref|NP_561888.1|_1:251 (NC_003366) probable histidinol phosphatase [Clostridium perfringens]
    • gi|18144632|dbj|BAB80678.1| (AP003188) probable histidinol phosphatase [Clostridium perfringens]
47. • gi|15614846|ref|NP_243149.1|_6:218 (NC_002570) BH2283~unknown conserved protein [Bacillus halodurans]
    • gi|10174903|dbj|BAB06002.1| (AP001515) BH2283~unknown conserved protein [Bacillus halodurans]
48. • gi|15673198|ref|NP_267372.1|_1:251 (NC_002662) histidinol phosphatase [Lactococcus lactis subsp. lactis]
    • gi|19862316sp|Q02150|HIS9_LACLA Histidinol-phosphatase (HolPase)
    • gi|12724185|gb|AAK05314.1|AE006353_13 (AE006353) histidinol phosphatase [Lactococcus lactis subsp. lactis]
49. • gi|15598396|ref|NP_251890.1|_1:224 (NC_002516) conserved hypothetical protein [Pseudomonas aeruginosa]
    • gi|11347987|pir||C83244 conserved hypothetical protein PA3200 [imported] - Pseudomonas aeruginosa (strain PAO1)
    • gi|9949320|gb|AAG06588.1|AE004744_3 (AE004744) conserved hypothetical protein [Pseudomonas aeruginosa]
50. • gi|20090155|ref|NP_616230.1|_3:210 (NC_003552) conserved hypothetical protein [Methanosarcina acetivorans str. C2A]
    • gi|19915139|gb|AAM04710.1| (AE010798) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
51. • gi|21228391|ref|NP_634313.1|_2:207 (NC_003901) hypothetical protein [Methanosarcina mazei Goe1]
    • gi|20906864|gb|AAM31985.1| (AE013471) hypothetical protein [Methanosarcina mazei Goe1]
52. • gi|15805497|ref|NP_294193.1|_4:248 (NC_001263) histidinol phosphatase, putative [Deinococcus radiodurans]
    • gi|18203432sp|Q9RX45|HIS9_DEIRA Probable histidinol-phosphatase (HolPase)
    • gi|7473516|pir||F75515 probable histidinol phosphatase - Deinococcus radiodurans (strain R1)
    • gi|6458156|gb|AAF10049.1|AE001906_5 (AE001906) histidinol phosphatase, putative [Deinococcus radiodurans]
53. • gi|478083|pir||D47754_1:251 orf13 3' to hisIE - Lactococcus lactis subsp. lactis
    • gi|2565149|gb|AAB81911.1| (U92974) unknown [Lactococcus lactis]
54. • gi|2735355|gb|AAB93886.1|_4:192 (U92714) TrpH [Salmonella typhimurium]
55. • gi|17230432|ref|NP_486980.1|_28:220 (NC_003272) hypothetical protein [Nostoc sp. PCC 7120]
    • gi|17132034|dbj|BAB74639.1| (AP003591) ORF_ID:alr2940~hypothetical protein [Nostoc sp. PCC 7120]
56. • gi|21223530|ref|NP_629309.1|_1:217 (NC_003888) conserved hypothetical protein [Streptomyces coelicolor A3(2)]
    • gi|9714446|emb|CAC01362.1| (AL390975) conserved hypothetical protein [Streptomyces coelicolor A3(2)]
57. • gi|15615934|ref|NP_244238.1|_12:218 (NC_002570) BH3372~unknown conserved protein in others [Bacillus halodurans]
    • gi|10175995|dbj|BAB07091.1| (AP001518) BH3372~unknown conserved protein in others [Bacillus halodurans]
58. • gi|16331686|ref|NP_442414.1|_51:241 (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
    • gi|7469896|pir||S75749 hypothetical protein sll0549 - Synechocystis sp. (strain PCC 6803)
    • gi|1001243|dbj|BAA10484.1| (D64003) ORF_ID:sll0549~unknown protein [Synechocystis sp. PCC 6803]
59. • gi|18310352|ref|NP_562286.1|_2:253 (NC_003366) probable histidinol phosphatase [Clostridium perfringens]
    • gi|18145032|dbj|BAB81076.1| (AP003190) probable histidinol phosphatase [Clostridium perfringens]
60. • gi|20090633|ref|NP_616708.1|_4:223 (NC_003552) ribonuclease P, subunit p30 [Methanosarcina acetivorans str. C2A]
    • gi|19915676|gb|AAM05188.1| (AE010857) ribonuclease P, subunit p30 [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
61. • gi|15643567|ref|NP_228613.1|_2:218 (NC_000853) conserved hypothetical protein [Thermotoga maritima]
    • gi|18203585sp|Q9WZR1|HIS9_THEMA Probable histidinol-phosphatase (HolPase)
    • gi|7462247|pir||E72330 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
    • gi|4981334|gb|AAD35886.1|AE001748_2 (AE001748) conserved hypothetical protein [Thermotoga maritima]
62. • gi|20808955|ref|NP_624126.1|_1:256 (NC_003869) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
    • gi|20517619|gb|AAM25730.1| (AE013201) Histidinol phosphatase and related hydrolases of the PHP family [Thermoanaerobacter tengcongensis]
63. • gi|18310038|ref|NP_561972.1|_5:261 (NC_003366) histidinol phosphatase [Clostridium perfringens]
    • gi|18144717|dbj|BAB80762.1| (AP003189) histidinol phosphatase [Clostridium perfringens]
64. • gi|21228720|ref|NP_634642.1|_6:223 (NC_003901) hypothetical protein [Methanosarcina mazei Goe1]
    • gi|20907229|gb|AAM32314.1| (AE013507) hypothetical protein [Methanosarcina mazei Goe1]
65. • gi|15895984|ref|NP_349333.1|_1:244 (NC_003030) Predicted PHP family hydrolase [Clostridium acetobutylicum]
    • gi|18202318sp|P58291|HIS9_CLOAB Probable histidinol-phosphatase (HolPase)
    • gi|15025762|gb|AAK80673.1|AE007770_6 (AE007770) Predicted PHP family hydrolase [Clostridium acetobutylicum]
66. • gi|18310865|ref|NP_562799.1|_1:247 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
    • gi|18145547|dbj|BAB81589.1| (AP003192) conserved hypothetical protein [Clostridium perfringens]
67. • gi|20799582|gb|AAM28554.1|_6:188 (AF495474) glyceraldehyde-3-phosphate dehydrogenase [Macrococcus caseolyticus]
68. • gi|16080014|ref|NP_390840.1|_1:258 (NC_000964) similar to hypothetical proteins [Bacillus subtilis]
    • gi|17376873sp|O34411|HIS9_BACSU Histidinol-phosphatase (HolPase)
    • gi|7474735|pir||D70002 histidinol-phosphatase (EC 3.1.3.15) [validated] - Bacillus subtilis
    • gi|2293321|gb|AAC00399.1| (AF008220) YtvP [Bacillus subtilis]
    • gi|2635446|emb|CAB14940.1| (Z99119) similar to hypothetical proteins [Bacillus subtilis]
69. • gi|16264478|ref|NP_437270.1|_24:233 (NC_003078) conserved hypothetical protein [Sinorhizobium meliloti]
    • gi|15140615|emb|CAC49130.1| (AL603644) conserved hypothetical protein [Sinorhizobium meliloti]
70. • gi|19075372|ref|NP_587872.1|_1:271 (NC_003421) histidinol-phosphatase [Schizosaccharomyces pombe]
    • gi|3183028sp|O14059|HIS9_SCHPO Probable histidinol-phosphatase (HolPase)
    • gi|7490638|pir||T41045 histidinol-phosphatase - fission yeast (Schizosaccharomyces pombe)
    • gi|3451302|emb|CAA20439.1| (AL031324) histidinol-phosphatase [Schizosaccharomyces pombe]
71. • gi|14600437|ref|NP_146951.1|_24:194 (NC_000854) hypothetical protein [Aeropyrum pernix]
    • gi|7515550|pir||H72761 hypothetical protein APE0085 - Aeropyrum pernix (strain K1)
    • gi|5103473|dbj|BAA78994.1| (AP000058) 243aa long hypothetical protein [Aeropyrum pernix]
72. • gi|21226610|ref|NP_632532.1|_6:173 (NC_003901) Isoleucyl-tRNA synthetase [Methanosarcina mazei Goe1]
    • gi|20904888|gb|AAM30204.1| (AE013276) Isoleucyl-tRNA synthetase [Methanosarcina mazei Goe1]
73. • gi|18311129|ref|NP_563063.1|_4:221 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
    • gi|18145812|dbj|BAB81853.1| (AP003193) conserved hypothetical protein [Clostridium perfringens]
74. • gi|20092421|ref|NP_618496.1|_1:167 (NC_003552) conserved hypothetical protein [Methanosarcina acetivorans str. C2A]
    • gi|19917677|gb|AAM06976.1| (AE011070) conserved hypothetical protein [Methanosarcina acetivorans str. C2A] [Methanosarcina acetivorans C2A]
75. • gi|18309997|ref|NP_561931.1|_3:200 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
    • gi|18144676|dbj|BAB80721.1| (AP003189) conserved hypothetical protein [Clostridium perfringens]
76. • gi|15791255|ref|NP_281079.1|_1:196 (NC_002607) Vng2493c [Halobacterium sp. NRC-1]
    • gi|10581888|gb|AAG20559.1| (AE005127) Vng2493c [Halobacterium sp. NRC-1]
77. • gi|13959345sp|Q9CDT7|DPO3_LACLA_507:633 DNA polymerase III polC-type (PolIII)
78. • gi|15674106|ref|NP_268281.1|_527:653 (NC_002662) DNA polymerase III, alpha chain (EC 2.7.7.7) [Lactococcus lactis subsp. lactis]
    • gi|12725180|gb|AAK06222.1|AE006440_8 (AE006440) DNA polymerase III, alpha chain (EC 2.7.7.7) [Lactococcus lactis subsp. lactis]
79. • gi|21314372|gb|AAM46912.1|AF508325_1_325:445 (AF508325) DNA polymerase III C [Enterococcus faecalis]
80. • gi|20808235|ref|NP_623406.1|_3:212 (NC_003869) DNA polymerase III alpha subunit [Thermoanaerobacter tengcongensis]
    • gi|20516832|gb|AAM25010.1| (AE013134) DNA polymerase III alpha subunit [Thermoanaerobacter tengcongensis]
81. • gi|15807227|ref|NP_295957.1|_35:210 (NC_001263) conserved hypothetical protein [Deinococcus radiodurans]
    • gi|7471273|pir||A75298 conserved hypothetical protein - Deinococcus radiodurans (strain R1)
    • gi|6460040|gb|AAF11783.1|AE002056_3 (AE002056) conserved hypothetical protein [Deinococcus radiodurans]
82. • gi|15614981|ref|NP_243284.1|_330:455 (NC_002570) DNA polymerase III (alpha subunit) [Bacillus halodurans]
    • gi|13959348sp|Q9KA72|DPO3_BACHD DNA polymerase III polC-type (PolIII)
    • gi|10175038|dbj|BAB06137.1| (AP001515) DNA polymerase III (alpha subunit) [Bacillus halodurans]
83. • gi|15900208|ref|NP_344812.1|_336:462 (NC_003028) DNA polymerase III, alpha subunit, Gram-positive type [Streptococcus pneumoniae TIGR4]
    • gi|21263563sp|Q97SQ2|DPO3_STRPN DNA polymerase III polC-type (PolIII)
    • gi|14971745|gb|AAK74452.1| (AE007340) DNA polymerase III, alpha subunit, Gram-positive type [Streptococcus pneumoniae TIGR4]
84. • gi|15902295|ref|NP_357845.1|_336:462 (NC_003098) DNA polymerase III, alpha subunit [Streptococcus pneumoniae R6]
    • gi|15457800|gb|AAK99055.1| (AE008406) DNA polymerase III, alpha subunit [Streptococcus pneumoniae R6]
85. • gi|15894377|ref|NP_347726.1|_3:200 (NC_003030) Predicted metal-dependent phosphoesterase (PHP family), YciV ortholog [Clostridium acetobutylicum]
    • gi|15024008|gb|AAK79066.1|AE007625_10 (AE007625) Predicted metal-dependent phosphoesterase (PHP family), YciV ortholog [Clostridium acetobutylicum]
86. • gi|18310673|ref|NP_562607.1|_347:467 (NC_003366) DNA polymerase III alpha subunit [Clostridium perfringens]
    • gi|18145354|dbj|BAB81397.1| (AP003191) DNA polymerase III alpha subunit [Clostridium perfringens]
87. • gi|21401801|ref|NP_657786.1|_329:474 (NC_003995) EXOIII, exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other [Bacillus anthracis A2012] [Bacillus anthracis str. A2012]
88. • gi|15643342|ref|NP_228386.1|_268:396 (NC_000853) DNA polymerase III, alpha subunit [Thermotoga maritima]
    • gi|6225287sp|Q9ZHF6|DPO3_THEMA DNA polymerase III polC-type (PolIII)
    • gi|7447209|pir||C72360 DNA polymerase III, alpha subunit - Thermotoga maritima (strain MSB8)
    • gi|3930535|gb|AAC80438.1| (AF065313) DNA polymerase III; family C DNA polymerase [Thermotoga maritima]
    • gi|4981093|gb|AAD35661.1|AE001732_6 (AE001732) DNA polymerase III, alpha subunit [Thermotoga maritima]
89. • gi|15675759|ref|NP_269933.1|_338:462 (NC_002737) DNA polymerase III (alpha subunit) [Streptococcus pyogenes] [Streptococcus pyogenes M1 GAS]
    • gi|14194673sp|Q9FDF9|DPO3_STRPY DNA polymerase III polC-type (PolIII)
    • gi|13622981|gb|AAK34654.1| (AE006619) DNA polymerase III (alpha subunit) [Streptococcus pyogenes M1 GAS]
90. • gi|19746871|ref|NP_608007.1|_338:462 (NC_003485) DNA polymerase III alpha chain [Streptococcus pyogenes MGAS8232]
    • gi|19749113|gb|AAL98506.1| (AE010106) DNA polymerase III alpha chain [Streptococcus pyogenes MGAS8232]
91. • gi|20807845|ref|NP_623016.1|_300:425 (NC_003869) DNA polymerase III alpha subunit, the Gram-positive type [Thermoanaerobacter tengcongensis]
    • gi|20516408|gb|AAM24620.1| (AE013100) DNA polymerase III alpha subunit, the Gram-positive type [Thermoanaerobacter tengcongensis]
92. • gi|15678604|ref|NP_275719.1|_8:164 (NC_000916) conserved protein [Methanothermobacter thermautotrophicus] [Methanothermobacter thermautotrophicus str. Delta H]
    • gi|2621654|gb|AAB85082.1| (AE000840) conserved protein [Methanothermobacter thermautotrophicus str. Delta H]
93. • gi|9789541|gb|AAF98345.1|_338:462 (AF280761) DNA polymerase III alpha chain [Streptococcus pyogenes]
94. • gi|15896683|ref|NP_350032.1|_338:466 (NC_003030) DNA polymerase III (alpha subunit) [Clostridium acetobutylicum]
    • gi|15026532|gb|AAK81372.1|AE007841_7 (AE007841) DNA polymerase III (alpha subunit) [Clostridium acetobutylicum]
95. • gi|15829133|ref|NP_326493.1|_8:142 (NC_002771) unknown; predicted coding region [Mycoplasma pulmonis]
    • gi|14090077|emb|CAC13835.1| (AL445565) unknown; predicted coding region [Mycoplasma pulmonis]
96. • gi|15679475|ref|NP_276592.1|_1:111 (NC_000916) conserved protein [Methanothermobacter thermautotrophicus] [Methanothermobacter thermautotrophicus str. Delta H]
    • gi|7429739|pir||H69063 conserved hypothetical protein MTH1478 - Methanobacterium thermoautotrophicum (strain Delta H)
    • gi|2622593|gb|AAB85953.1| (AE000908) conserved protein [Methanothermobacter thermautotrophicus str. Delta H]
97. • gi|15618576|ref|NP_224862.1|_1:230 (NC_000922) DNA Polymerase III Alpha [Chlamydophila pneumoniae CWL029]
    • gi|15836198|ref|NP_300722.1| (NC_002491) DNA polymerase III alpha [Chlamydophila pneumoniae J138]
    • gi|16752374|ref|NP_444633.1| (NC_002179) DNA polymerase III, alpha subunit [Chlamydophila pneumoniae AR39]
    • gi|14194705sp|Q9Z7N8|DP3A_CHLPN DNA polymerase III alpha subunit
    • gi|7434837|pir||B72050 DNA polymerase III, alpha chain CP0081 [imported] - Chlamydophila pneumoniae (strains CWL029 and AR39)
    • gi|4376966|gb|AAD18805.1| (AE001649) DNA Polymerase III Alpha [Chlamydophila pneumoniae CWL029]
    • gi|7189016|gb|AAF37967.1| (AE002171) DNA polymerase III, alpha subunit [Chlamydophila pneumoniae AR39]
    • gi|8979038|dbj|BAA98873.1| (AP002547) DNA polymerase III alpha [Chlamydophila pneumoniae J138]

              10                20        30        40             50  
              |                 |         |         |              |  
   1 MYPVDLHMHT.VAS..T..HA...YSTLSDYIAQAKQKGIKLFAITDHGPD.....MEDAPHHWH
   2 MYPVDLHMHT.VAS..T..HA...YSTLSDYIAQAKQKGIKLFAITDHGPD.....MEDAPHHWH
   3 MYPVDLHMHT.VAS..T..HA...YSTLSDYIAQAKQKGIKLFAITDHGPD.....MEDAPHHWH
   4 MYPVDLHMHT.VAS..T..HA...YSTLHDYIAEAKLKNIKLFAITDHGPD.....MADAPHYWH
   5 MYPVDLHMHT.VAS..T..HA...YSTLSDYIAEAKRKGIKLFAITDHGPD.....MEDAPHHWH
   6 DIQGDLHMHT.TWS..D..GA...-FSIEEMVQACRARGYKFMAITDHSQY.....LKVANGLTK
   7 -LVLDTHTHT.IAS..G..HA...FSTIIENAREAFRKGLQLICITDHGPE.....MPGGPHIYY
   8 DIRADLHMHT.TWS..D..GA...-HSIEEMAEAARQRGYEYIAITDHSKF.....LRVANGLSE
   9 DINGDIHMHT.TYS..D..GA...-FSIRDMVEANIAKGYKFMVITDHSQS.....LRVANGLQV
  10 DIRGDLHMHT.TWS..D..GA...-YAIPEMIEACIAKGYEYMVITDHGKF.....LRVANGLDE
  11 QIKGDLHMHS.TWS..D..GA...-FSIREMAEACIKKGYQYMAITDHSQY.....LKVANGLTA
  12 DIRGDLHMHT.TWS..D..GA...-YAIPEMIEACIAKGYEYMVITDHGKF.....LRVANGLDE
  13 DINGDIHMHT.TYS..D..GA...-FSIRDMVEANIAKGYKFMVITDHSQS.....LRVANGLQV
  14 -YLIDLHTHT.IVS..G..HA...YTTLLENIKQASQIGIKILGTSEHGPK.....MPGAPHIWY
  15 DLRGDLHMHT.DYS..E..GA...-ESLETMVEKAESMGYEYIAVTDHSRS.....QRIANGMDI
  16 -LEVETHCHT.IAS..G..HA...YNNLEEMVLEAQKKGLKGICITDHGPE.....MPGSCSSLY
  17 RLRGDCHLHS.DWS..D..GG...-SPIEEMGRTAAALGHEWAALTDHSPR.....LTVARGLSP
  18 DIKGVFHVHT.TYS..D..GR...-NSLEDMVRKARDLGYKYIAITDHSKS.....AFYANGLTE
  19 DIKGDLHMHT.NWS..D..GV...-NTLEEMVETAYKLGYQYIVIGDHSQS.....ARVANGLDP
  20 --AVDTHTHT.YAS..G..HA...YSTLIENARAAKQNGLTLFCTTDHAES.....MPGAPHYWF
  21 RLRGDCHLHA.DWS..D..GG...-SPMEEMGRTAAALGHEWAALTDHSPR.....LTVARGLSP
  22 DLKGDFHLHT.DYS..E..GR...-ASLETMVKKAETMGYEYIAVTDHSRS.....QRIAHGMEI
  23 -VIYDLHSHT.TAS..D..GL...-LTPETLVHRAVEMRVGTLAITDHDTT.....AAIPAA---
  24 -VIYDLHSHT.TAS..D..GC...-LTPEALVHRAVEMRVGTLAITDHDTT.....AAIAPA---
  25 -VIYDLHSHT.TAS..D..GC...-LTPEALVHRAVEMRVGTLAITDHDTT.....AAIAPA---
  26 -VIYDLHSHT.TAS..D..GL...-LTPETLVHRAVEMRVGTLAITDHDTT.....AAIPAA---
  27 ALRGDLHLHS.NWS..D..GS...-APIEEMMATAAALGHQYCALTDHSPR.....LTIANGLSP
  28 -TLYDLHSHT.TAS..D..GT...-LTPSELVIRAAQMRVGVLAITDHDTT.....AGLAEA---
  29 DLRGMIHTHS.TWS..D..GG...-ASIREMAEATLTLGHEFLGTADHSRA.....AYYANGLTI
  30 -MRIDLHSHT.TAS..D..GR...-FTYQQLIDRAVSFEIDVLAITDHDTV.....AALADA---
  31 ---MDLHTHT.IYS..D..GI...-GMVRDNVAWAEKRGLKIVGISDHIHY.....FTPSKFSAY
  32 PINADLHCHS.TVS..D..GL...-LAPREVAARAAAHGVTLWALTDHDEV.....GGQAAA---
  33 ---MDLHTHT.VYS..D..GI...-GLIRDNVAWAEKRGLKIVGISDHIHF.....FTPSRFSAY
  34 -MRFDFHTHT.VFS..D..GE...-LIPAELVRRARVLKHRAIAITDHADF.....SNYKELIEK
  35 ---MDLHTHT.IYS..D..GI...-GSVIDNVNMAEIRGLRLLGISDHIHF.....FTPSKFLKY
  36 ---IDLHCHS.TVS..D..GM...-LSPAEVVRLAHQNGCTLLALTDHDHT.....GGIAEA---
  37 -QLIDLHTHT.IFS..D..GE...-LLPSELVRRAVIHGYEAIALTDHADY.....TNLEQLLDA
  38 RIFADYHTHT.IYS..H..GK...-GTIEENVKKAVELGLKAIAITDHGPAhvfygMRKKDFKKM
  39 ---IDLHCHS.TVS..D..GM...-LSPAEVVRLAHQNGCTLLALTDHDHT.....GGIAEA---
  40 RKRIDLHTHS.LLS..D..GE...-LLPSELARRACVLGHEAIAITDHIDA.....SNINTITNL
  41 RLRADLHTHT.VYS..D..GH...-GTPLENVLAAEERGLETVALTDHGPA.....SPDGLTDRS
  42 EMFADLHMHS.KAS..D..GT...-NSPREVVRLAKAHGLSCIALTDHDTV.....DGLQEA---
  43 -TIYDLHCHS.TAS..D..GV...-LSPTEVVARAVEKGVNVLALTDHDTT.....AGLAEA---
  44 ---IDLHIHS.NYS..D..GQ...-GSVEEIARRAKERGLKAIAIVDHSIE.....LPFGLTEKK
  45 DIRGDLHMHS.LFS..D..GI...-DSMEQMAEYASVLGREYIAITDHARY.....IDDPDA---
  46 -MRSNYHTHT.YRC..N..HA...TGTIEDYVKEAIKANIDEIGISDHLPHp10hrMAYEDLEDY
  47 --NSDLHMHS.TAS..D..GG...-YSPTELMEKCHQANLKFVALTDHDTV.....NGIEEA---
  48 MKKLDYHFHS.HFS..A..DS...EELPRKHVTEAIAHGLEEICFTEHRDFyf6mdFSLNLPEYF
  49 -MRVDLHCHS.TAS..D..GV...-LAPAALVQRAHEKGVGLLALTDHDTL.....EGLPEA---
  50 -QLIDLHTHT.IFS..D..GE...-FLPSELVRHAVLHGYEAVAITDHADH.....TNLEWLLEA
  51 ---IDLHTHT.IFS..D..GE...-LIPSELVRRAVIHGYEAIALTDHADY.....TNLEQLLDA
  52 --LCDSHLHT.PLC..G..HA...TGTPREYAQAALDAGLSGLCFTDHMPM.....PRWYDA-PW
  53 MKKLDYHFHS.HFS..A..DS...EELPRKHVIEAIAYGLEEICFTEHRDFyf6mdFSLNLPEYF
  54 ----------.---..-..--...----------------GTLAITDHDTT.....AAIPAA---
  55 PKLFNFHMHT.VYS..D..GR...-LQPSVLMEQAIAIGLQGFAITDHHTV.....GGYEAAQAW
  56 -MRIDLHTHS.TAS..D..GT...-DTPAQLVRKAAATGLDVVALTDHDTT.....RGHAEA---
  57 ---FDLHIHT.TAS..D..GE...-YSPTAIVKKAKEIGLRTIAITDHDTL.....DGIEEA---
  58 PRFYNFHLHT.RCS..D..GQ...-MTPEGLIEQAIHQELQGLAITDHHCV.....AGYYRAQRW
  59 LKKINFHTHT.KRC..K..HA...KGEDKDYIDAAIKNNLDILGFSDHGPYpd8lrMNFNELEEY
  60 PKFYDFCVHA.VP-..D..GD...-STAQEQVSLGRHFGFSGIALANHSDR.....LPDRKP---
  61 ---IDMHLHS.TFS..Y..DG...KAEIDDIISQVQKLGIEHFCITDHYEY.....ENGELV--H
  62 -MPADYHVHI.ENG..P..FT...IEWLKEFVNQGLKRGLKEIGISEHGHRfk9ykSDGFRTEWI
  63 -TKRDGHVHS.TYC..Ph.GS...NDTLDMYIDTALKNGITEITFTEHMPLp12saLPMERLEEY
  64 --FYDFCVHA.VP-..D..GA...-NAVEELSSLSRHLGYSGIALANHSDK.....LPSKKP---
  65 -MVFDTHLHT.LFS..T..DS...KMNIEEAIDAGEKKNLGII-ITEHIDL.....NYPVKGEFV
  66 -MLYDCHIHT.EFS..A..DS...ELKIKDILEKAKKNNLGII-TTEHLDY.....NLKTHPQFA
  67 ----------.---..-..--...---------------------------.....---GRLLEQ
  68 MQKRDGHIHT.PFC..Ph.GS...NDTLRQYAEEALKKGFESITFTEHAPLp14saMAQASLERY
  69 QLNVEFQVHT.SWT..D..GQ...-ATALEILQTASERGLAELAFTEHVRE.....DTSWFP-EF
  70 -MPISSHSHSgQFC..L..HA...QGKLEDVIQEAIQQGFQSFSFTEHTPR.....DRVEDL--Y
  71 LMLVELHSHT.TVS..D..GF...-QTPMEIVKIAAKAGLAAIAVTDHDTF.....RGSSLA---
  72 IMKFDLHVHS.EHS..K..DS...NSSHRDIIEVARRRGLDGFAICDHDTV.....EGGLAC---
  73 -VRTDLHMHT.RAS..D..GT...-LTPKELLKEIVEKDIKLFSVTDHDSI.....GSLEEM---
  74 -MKFDLHVHS.EYS..R..DS...ESSHEDILENALKRGLDGFAICDHDTV.....EGGLAC---
  75 -INAEFHCHS.LAS..D..GT...-LSPKEVIAEAKKSGISLIALTDHDIT.....SGLDEA---
  76 MVHADLHVHT.TNS..D..GT...-LTIDAVPDAAHDAGVTAVAITDHDRL.....HPALDA---
  77 EKRVEFHAHT.NMS..Qm.DA...IPSASSLVAQAAKWGHKAIAITDHGGL.....QSFPEA---
  78 EKRVEFHAHT.NMS..Qm.DA...IPSASSLVAQAAKWGHKAIAITDHGGL.....QSFPEA---
  79 EKRVELHMHS.NMS..Tm.DA...TNKVGDLVAQAGKWGHKAIAITDHGGA.....QAFPDA---
  80 AMFVHLHVHT.EYSllD..GS...-CRIKDLIAKTKELGMKAIAITDHGAM.....YGVIDF---
  81 VMRMDLHCHT.EVS..H..DC...RTALRDIPGWLLRTNTRVMAVTDHDQF.....RGGPEL---
  82 EKRVELHLHT.AMS..Qm.DG...ISSAGAYVTQASKWGHKAIAITDHGVV.....QAFPEA---
  83 ERRVEFHAHT.NMS..Tm.DA...LPEVEEIVATAAKWGHKAVAITDHGNV.....QSFPHG---
  84 ERRVEFHAHT.NMS..Tm.DA...LPEVEEIVATAAKWGHKAVAITDHGNV.....QSFPHG---
  85 -LKGDFHIHT.NAS..D..GK...-YTPEKVLELAKTAGINILAITDHDTT.....SSVKKA---
  86 EKRVELHMHT.TMS..Sm.DA...VTAASKIVERAAKFGHKAVAITDHGVV.....QAFPDA---
  87 EKRVELHLHT.PMS..Qm.DA...VTPVSKLVAQAGKWGHEAIAVTDHAVA.....QSFPEA---
  88 VKRVELHAHT.KFS..Dq.DA...ITDVNEYVKRAKEWGFPAIALTDHGNV.....QAIPYF---
  89 QKRVELHAHT.NMS..Tm.DA...LPTVESLIDTAAKWGHKAIAITDHANV.....QSFPHG---
  90 QKRVELHAHT.NMS..Tm.DA...LPTVESLIDTAAKWGHKAVAITDHANV.....QSFPHG---
  91 EKRVELHLHT.QMS..Tl.DA...VPSATEVIKRAAEWGHKAVAITDHAVV.....QAFPEA---
  92 ----------.---..-..--...---------------------------.....---------
  93 QKRVELHAHT.NMS..Tm.DA...LPTVESLIDTAAKWGHKAIAITDHANV.....QSFPHG---
  94 EKRVELHMHT.KMS..Qm.DA...MTSATDLIKRAMSWGMKSIAITDHGVV.....QAFPEA---
  95 KIKIDLHLHS.PYS..StnGTkikWTSEEEAIRILKDNNIALASFTDHNTF.....----NFDFF
  96 MIRIDPHIHS.VYS..G..DA...RGTPREILRRASAVGLDAVAVADHNTM.....KGSIIA---
  97 MTWIPLHCHS.QYS..Vl.DA...MSSIKDFVAKGQEFGIPALALTDHGNL.....YGAVDF---


            60             70          80        90       100          
            |              |           |         |         |          
   1 FINMRIWPR.....VVDGVGILRGIEANIK..NVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHD.
   2 FINMRIWPR.....VVDGVGILRGIEANIK..NVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHD.
   3 FINMRIWPR.....VVDGVGILRGIEANIK..NVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHD.
   4 FMNMRVWPR.....LVDGVGILRGIEANIK..NLDGDIDCTGPMLDAVDLLIAGFHEPVFPPQD.
   5 FINMRIWPR.....LVDGVGILRGIEANIK..NINGEIDCSGKMFDSLDLIIAGFHEPVFAPHD.
   6 ERLREQAKEie6neKYPDITILRGIEMDIL..P-DASLDFDDEVLAELDYVIGAIHSSF--SQD.
   7 FGNLKVIPE.....KIEGVEILKGVEANIM..DEEGRIDLPERILKKLDIVIASLHDECFEPSEd
   8 ERLKEQHAKir6neRYDDFTIFTGIEMDIL..P-DGTLDYEDPILAEVDFVIASIHSSF--SQP.
   9 ERLLRQNEEik6dkEYSEIDIYSGTEMDIL..P-DGSLDYDDEILAQLDYVIGAIHQSF--NQS.
  10 KRLLEQQAEik6aaNYPEIDVYSGVEMDIL..A-DGSLDFDDDTLKQLDFVIASIHSSF--QQS.
  11 ERLKQQAKEid6naEFENFRILKGVEMDIL..P-DGTLDYDDDVLAEMDIVIASIHSSF--NQP.
  12 KRLLEQQAEik6aaKYPEIDVYSGVEMDIL..A-DGSLDFDDETLKQLDFVIASIHSSF--QQS.
  13 ERLLRQNEEik6dkEYSEIDIYSGTEMDIL..P-DGSLDYDDEILAQLDYVIGAIHQSF--NQS.
  14 FGNMNKVPR.....KIYDVTVLRGCEADIL..NSNGDLDIPERIQNELDYIIASLHDVCIEPGT.
  15 ETLKEQWKEikslsKRFRIKVLRGSEVEIL..K-DGSLDYPDEILKELDVVVGAVHSGF--AAS.
  16 FYNLIVVPR.....KINGIMVFRGCEANIV..DYEGRIDIPEDALKRLDFVIASLHDVCIPSGT.
  17 ARLREQLDVva6naTWAPFRLLTGIECDIL..D-DGSLDQEPELLERLDVVVVSVHSKL--RMD.
  18 EMLLRQWEEid6nkKYPDIVILKGIESDIL..P-DGSLDYEEEILKRFDMVVASIHSHF--RMS.
  19 ERYKQQWKEid8eyNPKGFYILKGAEVDIL..P-DGSLDLPDEVLEQFDFVVASVHSRF-----.
  20 FSNQRILPR.....FLEGVGVIRGVEANIL..NTQGEIDLHPSVDHNLDWVIGSFHEPVFHPAD.
  21 ARLREQLDVva6naTWAPFRLLTGIECDIL..D-DGSLDQEPELLERLDVVVVSVHSKL--RMD.
  22 DTLKAQWEEikklsKRFKIKILRGSEVEVL..K-DGSLDYPDEILKELDIVVGAVNSGF--SSS.
  23 ---REEISR.....CGLALNLIPGVEISTV..WENHEIHIVGLNIDIAHPAMRDFLAQQTHRRQa
  24 ---REEISR.....SGLALNLIPGVEISTV..WENHEIHIVGLNIDITHPLMCEFLAQQTERRNq
  25 ---REEISR.....SGLALNLIPGVEISTV..WENHEIHIVGLNIDITHPLMCEFLAQQTERRNq
  26 ---REEISR.....SGLALNLIPGVEISTV..WENHEIHIVGLNIDIAHPAMRDFLAQQTERRQa
  27 DRLRKQLDVid6reKFAPLRILTGIEVDIL..E-DGSLDQEPEMLDRLDIVVASVHSKL--SMD.
  28 ---AAAIEQ.....HQLALRLIPGVEISTL..WENHEIHIVGLGIDVQHVSLRTLLEAQSEHRYq
  29 ERLREQLKEirel.QRAGLPIVAGSEVDIL..D-DGSLDFPDDVLGELDYVVVSVHSNF--TLD.
  30 ---RAYIAQ.....QQYPLQLVNGIEISTV..WQNKDIHIVGLNIDPNSEALGQLIARQQQRRVe
  31 INEIRIAKE.....-ESDIVVLAGIEANIL..E--NGPDITDEFRKRLDYVIASVHEWF--GRDg
  32 -----REAA.....ESLGMDYLAGVEISVT..WAGRTLHIVGLGIDPDDAALVQGLARTRSGRCa
  33 INEINVIKE.....-ESEIVVLAGIEANIL..E--NGPDITDEFRKKLDYAIASVHEWF--GRNg
  34 TTIAKEELKk....YWDDIIVIVGVELTHI..P-PKSIPKMAKKAKDLGAEIVVVHGET---VV.
  35 VNEVRSIGR.....-EAEIPVLVGIEANIT..E--NGPDVTEDFAKHLDYVIASVHDWFGEGE-.
  36 -----RAEA.....DKLGLRLINGVEISVT..WRGRTIHVVGLDFDEQDENLQNLLAQVRKGRLk
  37 AKKAKYLEE.....-EWDIRVLPGVELTHV..P-PRKIAPMAKKAKELGAEIVVVHGET---IY.
  38 RDEIDRLRE.....KYSQIKILMGVEANLI..SIEGDIDVPDELLKYLDILLVGYHTGIVPKSFk
  39 -----RAEA.....DRLGLRLINGVEISVT..WRGRTIHVVGLDFDERDENLQNLLAQVRQGRLk
  40 IDAVEDIGD.....-NWDITVIPGAEITHA..P-VEIIEKLAVRARRLGAEVIVVHGET---LV.
  41 FRRLVAEAReae..KLCSVRVYVGVEANIV..SISGEIDATPAMLSESDIVLAAIHNPRLILANp
  42 -----IEAS.....FELGIEVIPGIEFNCY..YKDQEVHILGYYIDYEDRGFVDKLEEMKKLRNd
  43 -----RLAA.....QQTDLTLISGVEISTT..WENRAIHIVGLGFDETSAKMTALLRQQAALRYq
  44 ARMREIEIEnaa..SLYGIKIYSGIECSIN..A-AGEIVLPDFDFD---FIIASVHEFV----Y.
  45 ---YFRAAE.....RIEEIDVLAGVEVSIL..H-DGNLEVPDGALKNFDLVIASIHDPG-----.
  46 FGKIEEAIEk....YGDKISIKRSIECEYF..PDFGWLYEELKDKYKADYLALGVHFFPYKGEWv
  47 -----KQTA.....HRLGFILIPGIELSTK..ASGQSVHMLGYGIDWKNDTLKRRLDRQQDIRKq
  48 QEINRLQAE.....FKDKIKIKIGLEMGID..LRFKSEINQFIDSAPFDFVIASVHEIGDIEVYd
  49 -----HQAA.....ARLGIELVNGVELSCT..WGGATIHVLGYGFDLDAAPLRQATEALHRGRWa
  50 AKKAKYLEE.....-EWDIRVLSGVELTHV..P-PRKIAPLSKKAKELGAEIVVVHGET---IS.
  51 AKKAKYLEE.....-EWDIRVLSGVELTHV..P-PRKIAPMAKKAKELGAEIVVVHGET---IS.
  52 RMKLEQLPEy11qeFAGRLDVRLGLEADFH..PGTEKFVEKVLGMFDWDYVIGSVHYLGAWGFDn
  53 QEINRLQAE.....FKDEINIKIGLEMGID..LRFKSEINQFIDSAPFDFVIASVHEIGDIEVYd
  54 ---REEISR.....SGLALNLIPGVEISTV..WENHEIHIVGLNIDIAHPAMRDFLAQQTERRQa
  55 LENWKWNNP.....GVTTPHLWSGVEINAN..LLDVEVHILAYAFQPEHFSLKPYLQRKITTDR.
  56 ------VAA.....LPEGLTLVTGAELSCR..LDGVSMHMLAYLFDPEEPALLAERELVRDDRVp
  57 -----VIAG.....KRHGINVIPAIELTTK..YKGTNVDILGYNVKASEKLQAILVQLKKHREGr
  58 LTEHCHYPS.....--LRPQLWTGIEITAN..LDGTEVHILGYDFDPTHPVLDPYLTGDRPDKY.
  59 KSTLEKLKIk....FKNFIQIKIGLEIEYL..PSDDFYYNYLKNELKFDYLALGQHLFLTENGEl
  60 ------ILP.....FIEGFEVFRGIELVEE..NPSKLHSLIGKFRNSMDVLIVHGGSEA-----.
  61 DFNVEEYFL.....TMEKYDLPKGAEIS--..WDGVGEAVFPDGFDYLLLGIHRYDENLPPDEL.
  62 KTYMDQSIEdy9eaKQMGLPVKLGIEADYF..PGKEKEIRDFLTLYLWDFIIGSVHWIDDWGIDl
  63 IKGITELKEk....VKDKIKVNLGLEVDYVegYEEETKAILNKYGKYLDDAILSVHIVKFQGEYy
  64 -----VLPS.....-IEGFEVFRGIELVEE..NPSKLHGLVGKFRSSMDVLIVHGGSEA-----.
  65 FDIDKYFKEyn...KYRSNKVLLGVEIGMG..EEIKEQNKSINDKYEFDYVLGSIHLLNGLDLYe
  66 ELDIEGYLKeys..KYRGENMQQGVELGLAmnNVDENFAFYEKYKDKFDMIIGSIHSINGVTLSr
  67 HARVKALDA.....QYPEIDIYSGVEMDIL..A-DGEMDYSNDVLAQLDYCIGAIHQSL--NQS.
  68 IHEISGLKKe....YRGQLSIRTGLEVDYIaeFEDEITLFLDTYGPYLDDSILSVHFLRTDSSYl
  69 RDEIRSAAR.....GFDHMSVYVGCETKAM..DDDGRLDVSQDVLDGCDIVLGVVHRLPDGRGGy
  70 PEELHLQPEd19qnYGDQINILIGAETEYIr.PESVELLKSLNTKYNLDYFVGSVHHVNSIPIDf
  71 ----KRAAK.....LLGGVAVIPAAEVRSE..WGDVVVLCSNDVSDDFPRAIEELREWA-----.
  72 ---AEKALE.....LGLEITVLPGVEVSSS..--KGHILVLGVKENI---------------EP.
  73 -----QDLT.....EEMDIKFIPGVEVSSI..INGEQFHILAYNFDKNNKELMSLIENN--DRLl
  74 ---AKKALE.....LGLEITVIPGVEVSSS..--KGHILVLGIKEDI---------------EP.
  75 -----KEAA.....KELDIQFIPGIELSCE..HKGSTIHILGYFRDD-----------------.
  76 ------PVT.....VRDDITVIHGIELRVD..TGPQRVDLLGYGVHGTDALTAECDRIQRDRRDr
  77 -----HSAG.....KKNGVKIIYGVEANLV..EDKIPIVYNETDVDMYESTYVVFDVET-TGLS.
  78 -----HSAG.....KKNGVKIIYGVEANLV..EDKIPIVYNETDVDMYESTYVVFDVET-TGLS.
  79 -----HAAG.....KKAGVKILYGVEANIV..DDGVPIAYNEEHIELTDATYVVFDVET-TGLS.
  80 -----YKEA.....VAQGIKPIIGCEIYVA..PRRMQDREYGIDDENYHLVLLAKDMTGYKNLMk
  81 ----QQLVRdlg..LDDRLSIICGEEITTS..E-------------------GELIGLFLQDRIp
  82 -----YGAS.....QKHGIKVIYGVEANLV..DDGVPIAYNEAHIPLLDSEFVVFDVET-TGLS.
  83 -----YKAA.....KKAGIQLIYGMEANIV..EDRVPIVYNEVEMDLSEATYVVFDVET-TGLS.
  84 -----YKAA.....KKAGIQLIYGIEANIV..EDRVPIVYNEVEMDLSEATYVVFDVET-TGLS.
  85 -----IAVG.....NELGIKVLPGIELSTL..KNGESIHILGYFRDI---SYENKDFQNFLTE-m
  86 -----QIAA.....KKNNIKVIYGVEGYLA..D-NGTPIVINGHEESFDDEYVVFDIET-----.
  87 -----YSAG.....KKAGVKVIYGVEANLV..NDGVPIAYNEEHRLLADETYVVFDVET-TGLS.
  88 -----YDAA.....KEAGIKPIFGIEAYLV..SDVEPVIRNLSDDSTFGDATFVVLDFETTGLD.
  89 -----YHRA.....RKAGIKAIFGLEANIV..EDKVPISYEPVDMDLHEATYVVFDVET-TGLS.
  90 -----YHRA.....RKAGIKAIFGLEANIV..EDKVPISYDPVDMDLHEATYVVFDVET-TGLS.
  91 -----MEAS.....REYGVKVIYGMEGYMV..D-DGIPIVTGESEASLEGEFVVFDIET-----.
  92 ---------.....--WDITVIPGAEITHA..P-VEIIEKLAVRARRLGAEVIVVHGET---LV.
  93 -----YHRA.....RKAGIKAIFGLEANIV..EDKVPISYEPVDMDLHEDLCGLSDVET-TGLS.
  94 ---HKLLGR.....DNPDMKIIYGVEAYLA..P-DKKPSVTNAKDQSIDTTYCVLDLET-TGFS.
  95 TRIQNLALE.....YSPKVVFLPGIEVDLV..RKDGKKGQSIFIFNPKQDLIKLQKHIKKIARK.
  96 -----LKES.....RGMGITVVPAMELSTS..A--G------------HIVALGIQEEI---SR.
  97 -----YKEC.....TQKGIQPIIGCECYIA..PGSRFDKKKEKRSRAAHHLILLCKNEQGYR--n


        110       120            130       140              150        
         |         |              |         |                |        
   1 ....KATNTQAMIATIAS.....GNVHIISHPGNPKYEIDV.....KA..VAEAAAKH.QVALEI
   2 ....KATNTQAMIATIAS.....GNVHIISHPGNPKYEIDV.....KA..VAEAAAKH.QVALEI
   3 ....KATNTQAMIATIAS.....GNVHIISHPGNPKYEIDV.....KA..VAEAAAKH.QVALEI
   4 ....KAANTQAMIATMAQ.....GNVHIISHPGNPKYPVDI.....PA..IAQAAAKY.NVALEL
   5 ....KETNTQAMIATIAS.....GKVHIISHPGNPKYPVEV.....KA..IAQAAAKH.HVALEI
   6 ....CETIMKRLRAALEN.....KHVTMIAHPTGRLLGRRE.....GY..DVDTDLLI.ELAKET
   7 ....VERNTKALINAIKN.....PYVDIIGHPGNPIYPIDI.....ER..VLEAAKEY.GKFIEI
   8 ....REKIMDRLKTALVN.....HHVDLIAHPTGRLIGRRE.....GY..DVDVDMLI.ELAKET
   9 ....EEQIMERLANACRN.....PYVRHIAHPTGRIIGRRD.....GY..KPNIEQLM.ALAEET
  10 ....EEEIMKRLKTACEN.....PYVRLIAHPTGRIVVKRK.....PY..HVNMKELI.KLAKNT
  11 ....EHVIMKRLETALTN.....KHVDIIAHPTGRLIGRRA.....GY..EIDIDQLI.ELARKT
  12 ....EEEIMKRLKTACEN.....PYVRLIAHPTGRIVVKRK.....PY..HVNMKELI.QLAKST
  13 ....EEQIMERLANACRN.....PYVRHIAHPTGRIIGRRD.....GY..KPNIEQLM.ALAEET
  14 ....IEDNTKALLNAMNN.....PNIDILGHTGNPMYPIDI.....DA..VVSKAKEK.NVLIEI
  15 ....EREMTGRIITALEN.....KHLDILAHPSGRLLGKRE.....AY..AVNFGKVF.EAAAEN
  16 ....VSDHTRALIGAIKN.....PYIHCIGHPGNPLYEIDK.....EE..VVLAAKEY.KKAIEI
  17 ....ARSMTRRMVAAVRD.....PHADVLGHCTGRLLTGRGrp...ES..AFDADEVF.AACAEA
  18 ....KEEMTKRVIKALEN.....KYTKILGHPTGRLLLARD.....SY..EIDVYAVI.DAAAHY
  19 ....EQDNTERIIKAMEN.....PYVNMIGHPTGKQYGYRE.....GY..PVNIEKLI.QKAKET
  20 ....KAAHTQALIETIKG.....GRVDALGHLGNPHFDFDF.....EQ..VIACAKAH.NVAIEI
  21 ....ARSMTRRMVAAVRD.....PHADVLGHCTGRLLTGRGrp...ES..AFDADEVF.AACAEA
  22 ....EREMTGRIVTALEN.....RHLDILAHPSGRLLGKRE.....AY..AVNFGTVF.ETAAAN
  23 11leKAHIPGAWEGALRL.....ANGGAVTRGHFARFLVEC.....GK..ATTMAEVF.KKYLAR
  24 11leKAHIPGALEGAQRL.....AQGGAVTRGHFARFLVEC.....GK..ASSMADVF.KKYLAR
  25 11leKAQIPGALEGAQRL.....AQGGAVTRGHFARFLVEC.....GK..ASSMADVF.KKYLAR
  26 11leKAHIPGAWEGALRL.....ANGGAVTRGHFARFLVEC.....GK..AATMADVF.KKYLAR
  27 ....SAAMTRRMVRAVAN.....GHTDVLGHCTGRLIAGNRgirp.ES..KFDAEAVF.TACREH
  28 11leKARIVGAWEGANRL.....ANGGQVTRGHFARYLVEL.....GL..ASNVGQVF.KKYLAK
  29 ....AARQTERLIRAVSH.....PLVTVLGHATGRLLLRRP.....GY..ALDLDAVL.GACEAN
  30 11lqKATREGVLEEVQHI.....ADGAPITRAHFAKWLVDN.....GY..ATNMQQVF.KKYLTR
  31 ....AHMYIEYVKRAIMD.....DNVDIIGHFGNSFPWIGY.....PT..EEEIREVL.ELAEAY
  32 11lgKLGIHGAYEGALSYa....GNPDMISRTHFARFLVEH.....GH..CRDIAEVF.DRYLGE
  33 ....THEYINYVKKAIMD.....DNVDIIGHFGNSFPWIGY.....PT..REEIDEIL.DLAEAY
  34 ....EPVEEKTNYYASIS.....EDVDILAHPGFID-----.....--..----KETA.ENLKEN
  35 ....VYRYIERIKLALMD.....ENVTIIGHFGNVFPWIGY.....PT..EEQIKEVL.DVAEEY
  36 11leKKGIGGAYDGALALa....ANKEMVSRTHVAEFLIQA.....GH..VKNKQQAF.TKYLGD
  37 ....EPVAPGTNAASAAC.....EYVDILAHPGLIS-----.....--..----EEDV.RTAAEN
  38 23evREKNTEAMVKAIKK.....YRIDIITHPG-------A.....KV..DIDTRKLA.RAAKES
  39 11leKKGIGGAYDGALALa....ANKEMVSRTHVAEFLIQA.....GH..VKNKQQAF.IKYLGD
  40 ....EPVIPGTNHAAVSC.....PEVDILAHPGLIT-----.....--..----IEDV.ELAREN
  41 g7elRRAIVHATIRCIES.....GEVHIIAHPVWILEQLRC.....YIt.AQEAEEIA.RVAADH
  42 11lnDLGIKITIEDVLEF.....TSEKFIGRPHIARAMVKK.....NY..VGSVKEAF.EKYIGV
  43 11laKVGIVDAFEQAKML.....A-TGEVTRAHYARLLVQM.....GK..VSNEGQAF.KKYLSQ
  44 ....GQAYYERVIRCLES.....HDVDVLGHPFSPLFGFDG.....RL..AEMDEKLL.DVVEER
  45 ....--NLTERLLAAMDH.....DPVSIIGHPTGRV-LGSP.....EP..VVDIERVI.EGAAEA
  46 12eiLMIYADFVVEAIKS.....GYFSYLAHPDLFGMTYKNwd9asKR..ILKAAEEM.NMPIEI
  47 11lkAAGVPLEQDAVLRY.....ADGGAIGRPHVAKALMDK.....GY..VRSVQEAF.EHYLAE
  48 14eaQREYLLACLDVVQNf....ENYNSFGHLDYVARYGPYt14ilFE..ILRALASK.EKALEI
  49 11laAKGMPGALEGARAIqqalgDSGNAPARPHFAEFLVQG.....GW..VKDRADAF.RKWLGA
  50 ....EPVAPGTNSASVAC.....EYVDILAHPGLIS-----.....--..----EEDV.QTAVDN
  51 ....EPVAQGTNAASAAC.....EYVDILAHPGLIS-----.....--..----EEDV.RTAAEN
  52 16glYRDYYALVEGAARS.....GLFDAIGHLDLPKKFGHLdp7yaLH..ALDVVAGQ.GLALDF
  53 14eaQREYLLACLDVVQNf....ETYNSFGHLDYVARYGPYt14ilFE..ILRALASK.GKALEI
  54 11leKAHIPGAWEGALRL.....ANGGAVTRGHFARFLVEC.....GK..AATMADVF.KKYLAR
  55 ....EYQAGNVIEAIHAA.....GGIAVLAHPARYRKSHFDlip..AA..AGYGIDGV.ETYYAY
  56 11lnELGVPVTWEQVARI.....AGGGSVGRPHVASALVEL.....GV..VPTVNDAFtRDWLAD
  57 10fnDIGFTITLDEVKQF.....SEDGVIARPHIAKAIVKK.....GY..VLDYQTVF.DEYLAD
  58 ....YAQAPKVIKALHDA.....GGLVVLAHPARYRQPASHlip..AA..ARHGIDGV.EAFYAY
  59 12keYIEYAKSICLGIKS.....GYFDFVAHPDLIFINDFPwd9acNL..IIDTAKKY.DFILEF
  60 ....------VNRAALEN.....PRVDILNHPAFDRSSGLN.....QV..LAKAAAEN.GVAIGI
  61 ....ARDYLERTLFVMER.....VKFHTLAHLDYPARYAKAdf9liEK..ILVFLVKN.EKALEI
  62 16evYLEYFNIIEKMAKT.....GLFDIIGHIDLVKIFGFRpn9kiER..NIEEISKT.GIVIEV
  63 23klYDLYYETMLKSIKCdlga.FKPKRIGHPTLVRKYKADf11llES..ILKEMKKG.NYEIDL
  64 ....------VNRAALEN.....PRVDILNHPAFDKSSGLN.....QV..LAKAAAEN.GVAIGI
  65 13evFEMYFKTMLACLRCh....EYIDSLAHIDYISRYAAYh14yiDE..VLKFIVDR.EIVIEI
  66 13vvYGEYLNNMLKCIEFy....DIFDTLGHIDYPCRYSTYdd8ltDF..KPKFQSIF.KTLIDK
  67 ....EDEIMKRLINACNN.....PYIRHIAHPTGRLIGRRN.....GY..HVNMPKLI.ETAQKT
  68 27qyYRSIYSSIVASLGV.....YKPKRVGHITLVQKFIKLf13lvSL..CLNAIEEN.GMELDF
  69 12etAGIEFRLSMGMVKN.....APIDVLAHPGGMSLRRHG.....RFp.ETYFRDLM.RATVER
  70 20qlFIDYFEHQYDLMQR.....LHPLVIGHFDLICLFAPEd16liQR..NIKYAVSY.GGIFEI
  71 ....-----------VER.....GCVTIAAHPGYSRYHGIPl....DA..IRRAASLF.DAIEVW
  72 ....LLSPEETILKARKL.....GGTVIIPHPFKRSSHGIG.....SF..EG------.---LDI
  73 q6dd--------------.....---------NSIKQLIDA.....GY..DIDFEDYL.SYEHDP
  74 ....RLSPEETIRRARKL.....GGTVIIPHPFKSSSHGIG.....SF..EG------.---LDT
  75 ....----------SYKSe....DFQKFLNELKDSRIGRAK.....KI..VANLEKYF.NIKLDY
  76 ....GRRIIDRVEARLGVslpl.EPRPGLGRPHIARAITAHp....-DtdYDTMDAVF.DSLIGN
  77 ....AVHNDLIQIAATKM.....HKGNPIDEFDEF------.....--..--------.------
  78 ....AVHNDLIQIAATKM.....HKGNPIDEFDEF------.....--..--------.------
  79 ....AVYDTIIELAAVKM.....HKGNVI------------.....--..--------.------
  80 41vpSLILRGDYEKAKEVal...FYDSIFGRGNFYLELQDH.....GI..--------.------
  81 p...KLTPEETVREIKAQ.....GGLVLLQHGFDPL----K.....RY..RLRPEATE.RIKDDI
  82 ....AVYNKIIELAAVKV.....KNGEIIDRFER-------.....--..--------.------
  83 ....AIYNDLIQVAASKM.....YKGNVIAEFDEF------.....--..--------.------
  84 ....AIYNDLIQVAASKM.....YKGNVIAEFDEF------.....--..--------.------
  85 17ld--TYFNIKLDYASIlk...EASNVIARPHIARAILAK.....GY..NYTYEYIF.NNILNK
  86 ....--------------.....------------------.....--..-TGFSSKN.DKIIEI
  87 ....AVYDTVIELAAVKV.....KGGEIIDRFESFANPHQPl13td--..--------.------
  88 ....PQVDEIIEIGAVKI.....QGGQIVDEYHTLI-----.....--..--------.------
  89 ....AMNNDLIQIAASKM.....FKGNIVEQFD--------.....--..--------.------
  90 ....AMNNDLIQIAASKM.....FKGNIVEQFD--------.....--..--------.------
  91 ....--------------.....------------------.....--..-TGLSNIN.DEIIEI
  92 ....EPVIPGTNHAAVSC.....PEVDILAHPGLIT-----.....--..----IEDV.ELAREN
  93 ....AMNNDLIQIAASKM.....FKGNIVEQFD--------.....--..--------.------
  94 ....PKTEKITEIGIMKY.....ENGKVIDKFSLFV-----.....--..--------.------
  95 ....WMYTYQEFLDQLKD.....FDFLAIPHIGK-------.....--..--------.------
  96 ....GLTPVETLDEIHDQ.....DGVAIIPHPFVRY-----.....--..--------.------
  97 79msEESIAGFKE-----.....------------------.....--..--------.-EWLKQ


      160                170           180              190       200  
       |                  |             |                |         |  
   1 NNSSFL.....H....SRKGSEDNC....REVAAAVRDAGG..W.....VALGSDSHTAFTMGE.
   2 NNSSFL.....H....SRKGSEDNC....REVAAAVRDAGG..W.....VALGSDSHTAFTMGE.
   3 NNSSFL.....H....SRKGSEDNC....RAVAAAVRDAGG..W.....VALGSDSHTAFTMGE.
   4 NNSSFA.....H....SRKGSEANC....RAIAAAVRDAGG..W.....LALGSDSHIAYALGI.
   5 NNSSFL.....H....SRKGSEDNC....RAVAAAVRDAGG..W.....VALGSDSHTAFTLGD.
   6 NTVLEL.....N....ANPNRLDLS....AKLLKQAQDAGV..K.....VAINTDAHTLEMLED.
   7 NNSSFV.....T....SRRGSEKIC....PIIAGKAKEMGV..R.....VAVGSDAHICFDVGR.
   8 NTALEL.....N....ANPNRLDLN....SEALKKAQEQGV..V.....MAINTDSHTKETFSY.
   9 NTVLEI.....N....ANPHRLDLN....AEIVRKYP--NV..K.....LTINTDAHHTNHLDF.
  10 GTALEL.....N....ANPQRLDLN....REHLEMAHAAGV..P.....IAINTDAHDTKHLDF.
  11 NTALEL.....N....ANPARLDLR....TEHLMKANEQGV..T.....LVINTDAHNIEMLDD.
  12 GTALEL.....N....ANPQRLDLN....REHLEMAHAAGV..P.....IAINTDAHDTKHLDF.
  13 NTVLEI.....N....ANPHRLDLS....ADIVRKYP--NV..K.....LTINTDAHHTNHLDF.
  14 NNGSLS.....G....SREGSYDNC....KKIAQACKKKGV..K.....VILGTDSHISFTIGN.
  15 GKVMEI.....N....CQPSRLDLN....DELIFRAKDYEL..K.....FCISTDSHSVSDLAS.
  16 NNSSFY.....-....VREKSKENC....IEILKLCKKYGV..Y.....IAMGSDAHYKADIGR.
  17 GTAVEI.....N....SRPERLDPP....RRLLRRAVAAGV..L.....FSIDTDAHAPGQLDW.
  18 GKIIEI.....N....SNPFRLDLD....WRYIKYAKEKGV..K.....FAINPDAHSVDGLED.
  19 GTALEL.....N....--TQRMDLS....PENVRKCMEAGV..Y.....IGIVTDAHSARQLHL.
  20 NNSTLKg....H....SRVGSIDRC....YEIARVAKSLDA..Y.....ITTGSDAHFCLDIGG.
  21 GTAVEI.....N....SRPERLDPP....RRLLRRAVAAGV..L.....FSIDTDAHAPGQLDW.
  22 GKVMEI.....N....SQPSRLDLN....DELILRAKEYGL..K.....FCISTDSHSMSDLAS.
  23 GKTGYV.....-....--PPQWCTI....EQAIDVIHHSGG..K.....AVLAHPGRYDLSAKW.
  24 GKTGYV.....-....--PPQWCTI....EQAIDVIHHSGG..K.....AVLAHPGRYNLSAKW.
  25 GKTGYV.....-....--PPQWCTI....EQAIDVIHHSGG..K.....AVLAHPGRYNLSAKW.
  26 GKTGYV.....-....--PPQWCTI....EQAIDVIHHSGG..K.....AVLAHPGRYDLSAKW.
  27 GTAVEI.....N....SRPERRDPP....TRLLHLARDIGC..V.....FSIDTDAHAPGQLDF.
  28 GKTGYV.....-....--PAQWCTI....EQAIDAIKQSGG..Q.....AVLAHPGRYDLTAKW.
  29 GTVVEI.....N....ANAARLDLD....WREALRWRE-RL..K.....FAINTDAHVPGGLRD.
  30 DNPGYV.....-....--PPNWCSM....SEAVSAIHAAGG..Q.....AVLAHPGRYDLTAKW.
  31 GKAFEI.....S....--SRYKVPD....LEFIKECIRRGI..K.....LSLATDAHRPEDVGK.
  32 GKPGFV.....-....--PHRWSRL....ADAIGWIRGAGG..V.....AVMAHPGRYTLTLLE.
  33 GKAFEI.....S....--ARYKVPD....LEFIRECVKRGI..K.....LSLATDAHRPEDVGK.
  34 DIFVEI.....T....SRRGHNITN....GYVANIAREFGL..K.....TLINTDTHAPEDLID.
  35 GKAFEI.....S....--SRYRVPD....LEFVKMCIKRGI..K.....LVFASDAHRPEDVGR.
  36 GKSCAV.....-....--RHEWATL....EDCVSAVNGAGG..M.....AVIAHPMRYDLSATA.
  37 NVLLEL.....T....ARNGHNRTN....GHVARLALELGA..K.....LVVNTDTHAPEDLIT.
  38 RTALEI.....N....--SSHGYLT....VEYVKIAKEEGC..K.....FVINSDAHTPSRVGD.
  39 GKSCAV.....-....--RHEWATL....EDCVSAVNGAGG..M.....AVIAHPMRYDLSATA.
  40 DVTLEI.....S....ARKGHCLGN....GHVAAIAGEVGV..P.....IVIDTDTHAPGDLID.
  41 NVGLEL.....N....--ARHLPRD....FTLYQVAIRVGA..P.....ITFGSDAHAPEEVGR.
  42 GGPAYV.....-....--ERYRITP....MEAIDLILENGG..V.....PVLAHPGLLSDDSV-.
  43 GKSCYV.....-....--KAQWCDI....PTAIEVIHQTGG..L.....AVLAHPLRYTLTNKW.
  44 GVAVEL.....N....--SSHKSPQ....DEFLQLCRDRKI..A.....YSIGSDAHSLSGVGE.
  45 GVALEV.....N....SNPLRIDLR....DTHVKMAVDMGC..K.....IAINSDAHSRGALEN.
  46 NVNGMRkn6syN....NGERYQYPI....KEFWELSKEYNV..K.....RIVGIDAHNPEEMHD.
  47 GRPCYV.....K....--RQEYISV....EQAIAWIHQAGG..V.....AIVAHPGYYDLDDQ-.
  48 NTRLFD.....D....--PKTEQFY....SDLLINFKKLGGk.F.....ITLGTDSHIAKRDWLs
  49 GKLGDV.....-....--KQHWPTL....EEVVGCLREARA..W.....ISLAHPYHYDFTRTK.
  50 NVLLEI.....T....TRNGHNRTN....GHVARLALEIGA..T.....LVVNTDTHGPGNLIT.
  51 NVFLEL.....T....ARNGHNRTN....GHVARLALEFGA..T.....LVVNTDTHAPENLIT.
  52 NTAGWR.....-....KPVAEAYPA....PDLVRAAAERGI..P.....FVLGSDAHQPGEVGFr
  53 NTRLFD.....D....--PKTGQFY....SDLLINFKRLGGk.F.....ITLGTDSHIAKRDWLs
  54 GKTGYV.....-....--PPQWCTI....EQAIDVIHHSGG..K.....AVLAHPGRYDLSAKW.
  55 NNPNPW.....-....--KPSVIES....EQIQNLAKEYGI..F.....NTCGTDTH-------.
  56 GGRAHV.....-....--GKHETDP....FEALRLIKGAGG..V.....AVFAHPAAAKRGRTV.
  57 GKPCAI.....-....--DKMILTP....EEGIKLIHEAGG..K.....AILAHPVYLEDT---.
  58 GNPKPW.....-....--QSSVPQM....EEVCYLGDLYNL..F.....RTCGTDSH-------.
  59 NANGIRrg6tyS....DGERFPYPY....EKFWNKASLAKV..K.....TIINSDCHTPCDLWDn
  60 ILRPLL.....H....SRGSRRIRLlsdlKSNLELARKYDV..S.....LVLCSDAMSCFDLRS.
  61 NTAGLF.....K....--HGKPNPD....YWIVEMYYDLGGr.V.....VTIGSDAHESQHIGRg
  62 STAGLR.....-....KPVGEIYPS....KEIMAMIKKYNI..P.....VVVNSDAHYPEHVGYe
  63 NTSGLR.....R....EKCGEVHPQ....GIFLDLCLKYNI..P.....MVLGSDSHSSKYVGVe
  64 TLRPLL.....H....SRGSRRIRMlsdlKANLELARKYDV..P.....LVLCSDAMSCYDLRS.
  65 NTRRLN.....K....--KEVCENL....MPIYKRYSELGGr.F.....VTIGSDSHYKDSIGLn
  66 NKVLEL.....NttrlDDETSFKNM....VEIYSYYRELGGk.Y.....ITLGSDSHKIEHVGRn
  67 NTILEI.....N....AHPMRLDLS....SDVLKQYPD--I..K.....LVINTDARAIDQLDL.
  68 NTSGLR.....K....TYAGGIYIE....DWMLNEAKQKKI..P.....LVFGSDAHQAGDVG-.
  69 RIAIEI.....N....--SSYLVDM....PAFLALCEEVNP..F.....VSIGSDAHRLSELGH.
  70 NTSAFR.....-....KGWKTAYPQ....QRLLELMVEQGA..Q.....LTLSDDSHGPHQVGLn
  71 NAYTPP.....H....-------FN....FMAIRLAEDLNH..T.....PVSGSDAHVPSMVGV.
  72 DAVEVF.....N....SRCLFNSAN....RKALEEAKRLGI..P.....GVAGSDSHIPEMVG-.
  73 SKGGWK.....-....--TLNFLID....RGICKNIDEFFN..K.....IFVGERALKYPDFPH.
  74 DAVEVF.....N....SRCLFNGAN....RKALVEAERLGI..P.....AVAGSDSHIPEMVG-.
  75 KDVLAK.....-....--GKGVVAR....PHIAQCIIDAGYpy-dw9nfIGNDSPAYVPNKKIS.
  76 DGPCFV.....-....--ARDVPDF....ETGVDLLTDACG..L.....VGLAHPLRYDDPQHA.
  77 ------.....-....---------....------------..-.....---------------.
  78 ------.....-....---------....------------..-.....---------------.
  79 ------.....-....---------....------------..-.....---------------.
  80 ------.....-....--LEQKKVN....RELVRMSKETGI..P.....LVATNDVHYLE----.
  81 DIVETF.....N....SRLSRHHWN....REAARWGEVHGHl.P.....QSAGSDAHTLRDIG-.
  82 ------.....-....---------....------------..-.....---------------.
  83 ------.....-....---------....------------..-.....---------------.
  84 ------.....-....---------....------------..-.....---------------.
  85 ESPAYI.....-....--PNKKVSV....EEGIKLLKAANA..V.....VVLAHPVLIKKT---.
  86 GAVKLK.....D....--GEIVD--....------------..-.....---------------.
  87 ------.....-....---------....------------..-.....---------------.
  88 ------.....-....---------....------------..-.....---------------.
  89 ------.....-....---------....------------..-.....---------------.
  90 ------.....-....---------....------------..-.....---------------.
  91 GAVKIK.....N....--KKIVDTF....ETF---------..-.....---------------.
  92 DVTLEI.....S....ARKGHCLGN....GHVAAIAGEVGV..P.....IVIDTDTHAPGDLID.
  93 ------.....-....---------....------------..-.....---------------.
  94 ------.....-....---------....------------..-.....---------------.
  95 ------.....-....---------....------------..-.....---------------.
  96 ------.....-....---------....------------..-.....---------------.
  97 EYYSLI.....-....--EKQIKVN....TAVLEASKRLGI..P.....TVATNDIHYIN----.


             210            220       230       240     
              |              |         |         |     
   1 .FEECLKILDAVDF.....PPERILNVSPRRLLNFLESRGMAPIAEFADL
   2 .FEECLKILDAVDF.....PPERILNVSPRRLLNFLESRGMAPIAEFADL
   3 .FEECLKILDAVDF.....PPERILNVSPRRLLNFLESRGMAPIAEFADL
   4 .FEHCERIIAEVNF.....PQERILNVSPRRLLDYLEQRGRPAIPELAE-
   5 .FTECRKILDAVNF.....PEDRILNVSPQRLLAFLESRGMAPVPEFAE-
   6 .METGVAAARKGWI.....QKDNVINTWDIERLLDYIK------------
   7 .FDEAIRLLEDINM.....PEELVLNTSVDKVKQYLQE------------
   8 .MEYGVGVARKGLI.....RPETVINTWPLERFCAFLR------------
   9 .MNYGVATAQKGFV.....TKDRVINALSREAFKDFIENN----------
  10 .MSIGVRAATKAWL.....DKSAILNTKSAAEFKQFLQ------------
  11 .MKTGVTAARKGWT.....ETKNVLNARSLKDVEAFLK------------
  12 .MSIGVRAATKAWL.....GKSAILNTKTAAEFKQFLQ------------
  13 .MNYGVATAQKGFV.....TKDRVINALSREAFKDFIEN-----------
  14 .FDKVQKLLDSVDM.....PKELIMNTDEKKIVEYLKAK-----------
  15 .MRYGLGQARRSWL.....EKEDIVNTYPYSRLKEV--------------
  16 .CEITQKLVCEYEF.....PPELIVNKGLESFISFLKLH-----------
  17 .QIHGCARAEECGV.....PPERVVTTWSLDELLAWTREGRTP-------
  18 .VKYGVGIARKGWL.....EARDVINTYEVEEVLT---------------
  19 .MFLGVGLARRGWA.....TPDKVINTFDLEGLKEFVYKKR---------
  20 .LSLASQLIDEVGI.....NPQRVITHTARQFLDFLELRGRQPIEEFAG-
  21 .QIHGCARAEECGV.....PPERVVTTWSLDELLAWTREGRTP-------
  22 .MRYGLGQARRGWL.....EKEDVVNTYPYSRLKEV--------------
  23 .LKRLVAHFADHHG.....DAMEV--------------------------
  24 .LKRLVAHFAEHDG.....DAMEV--------------------------
  25 .LKRLVAHFAEHHG.....DAMEV--------------------------
  26 .LKRLVAHFADHHG.....DAMEV--------------------------
  27 .LGYGAQRALDAEV.....PADRIVNTWPADTLLA---------------
  28 .LKRLLAHFAEHGG.....DAMEVA-------------------------
  29 .ARYGVMQARKAGL.....TPAHVVNSLGRAEFLDFVAR-----------
  30 .LKRLMTAFVEAGG.....DAMEV--------------------------
  31 .ISWSLKMFEKAGG.....SKED---------------------------
  32 .HGALFDEFKDLGG.....EGVEVV-------------------------
  33 .VSWSLKMLEKAGG.....TKED---------------------------
  34 .DEFAKKVGLGAGL.....TNKELENTLLHYPKELL--------------
  35 .VDWSIKVFEKAGG.....KKED---------------------------
  36 .KRNLFEEFKNLGG.....AGIEV--------------------------
  37 .DETALQIAMGSGL.....TESGAKDAFEAS-------------------
  38 .FKKGIQIAKEAGL.....TEEDVIN------------------------
  39 .KRNLFEEFKNLGG.....AGIEV--------------------------
  40 .YEMARRIGLGAGL.....TESGVEEALVKNPRRLLKRNG----------
  41 .FKPLQKLARRLGI.....EPQDV--------------------------
  42 .-------------.....-------------------------------
  43 .VKKLIADFAQWGG.....DAIEVAG------------------------
  44 .VGWSVEKA-----.....-------------------------------
  45 .ISWGVITARRGWA.....EAGDVLNTMGLRGFMKW--------------
  46 .LDMGLNFAKEHDL.....-------------------------------
  47 .---LIGWVREYGL.....DGIEV--------------------------
  48 .IHKARTLIKKAGF.....HE-----------------------------
  49 .RRRLVADFLQAGG.....HAIEVVN------------------------
  50 .DETALKIAMGAGL.....TESRVKEAFEAS-------------------
  51 .DETALKIAMGAGL.....TESRAKEAFKAS-------------------
  52 .FADAVKEIRDVGG.....-------------------------------
  53 .IHKARTLIKKAGF.....RE-----------------------------
  54 .LKRLVAHFADHHG.....DAMEV--------------------------
  55 .-------------.....-------------------------------
  56 .SEAAIADLAAAGL.....DGIEV--------------------------
  57 .---LVRELLALDF.....DGIE---------------------------
  58 .-------------.....-------------------------------
  59 tMDYAYTLANNLNL.....-------------------------------
  60 .PMEMLALAEVCGL.....EEDEALEAISTVPEKIIAKNRPGP-------
  61 .IEEVMRELKKFNF.....E------------------------------
  62 .FEKAYNYVKEFGI.....-------------------------------
  63 .FE-----------.....-------------------------------
  64 .PMETLAFAEVCGL.....EEDEALDALSTVPKKIIKKNRPGP-------
  65 .FKNALKMAENCNL.....KP-----------------------------
  66 .FERLYKFLEETKL.....TP-----------------------------
  67 .MKYGVGTAIKGHV.....KKEQVINTLPRKDFKSWIQN-----------
  68 .-------------.....-------------------------------
  69 .-------------.....-------------------------------
  70 .YHLAKSYLDKCGI.....TSL----------------------------
  71 .-------------.....-------------------------------
  72 .-------------.....-------------------------------
  73 .PKEVIETIKKANGiv6ahPKYGKSQFKLDEMLELFKNWGVDGIECYHP-
  74 .-------------.....-------------------------------
  75 .VEEGINILKANNA.....----------ITVLAHPKLIKRV--------
  76 .L------------.....-------------------------------
  77 .-------------.....-------------------------------
  78 .-------------.....-------------------------------
  79 .-------------.....-------------------------------
  80 .-------------.....-------------------------------
  81 .-------------.....-------------------------------
  82 .-------------.....-------------------------------
  83 .-------------.....-------------------------------
  84 .-------------.....-------------------------------
  85 .-------------.....-------------------------------
  86 .-------------.....-------------------------------
  87 .-------------.....-------------------------------
  88 .-------------.....-------------------------------
  89 .-------------.....-------------------------------
  90 .-------------.....-------------------------------
  91 .-------------.....-------------------------------
  92 .YEMARRIGLGAGL.....TESGVEEALVKNPRRLLKRNG----------
  93 .-------------.....-------------------------------
  94 .-------------.....-------------------------------
  95 .-------------.....-------------------------------
  96 .-------------.....-------------------------------
  97 .-------------.....-------------------------------