PFRMAT SS TARGET T0147 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0147.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0147.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0147.t2k.str.rdb (weight 1.53983) METHOD T0147.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0147.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0147 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0147.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 80 METHOD METHOD ============================================ METHOD Comments from T0147.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0147 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0147.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 80 METHOD METHOD ============================================ METHOD Comments from T0147.t2k.str.rdb METHOD ============================================ METHOD TARGET T0147 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0147.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 80 METHOD METHOD ============================================ METHOD Comments from T0147.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0147 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0147.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 80 METHOD METHOD ============================================ MODEL 1 M C 0.90 Y C 0.73 P C 0.60 V C 0.56 D C 0.50 L E 0.69 H E 0.73 M E 0.74 H E 0.65 T C 0.53 V C 0.54 A C 0.71 S C 0.82 T C 0.81 H C 0.82 A C 0.75 Y C 0.74 S C 0.80 T C 0.84 L H 0.93 S H 0.95 D H 0.96 Y H 0.96 I H 0.96 A H 0.96 Q H 0.96 A H 0.95 K H 0.95 Q H 0.90 K C 0.61 G C 0.94 I C 0.88 K C 0.52 L E 0.92 F E 0.93 A E 0.93 I E 0.89 T E 0.60 D C 0.74 H C 0.81 G C 0.77 P C 0.69 D C 0.65 M C 0.68 E C 0.68 D C 0.53 A H 0.56 P H 0.57 H H 0.68 H H 0.76 W H 0.78 H H 0.84 F H 0.87 I H 0.87 N H 0.88 M H 0.87 R H 0.86 I H 0.84 W H 0.79 P H 0.81 R H 0.77 V H 0.66 V C 0.48 D C 0.74 G C 0.88 V C 0.70 G E 0.63 I E 0.73 L E 0.58 R C 0.51 G E 0.57 I E 0.81 E E 0.89 A E 0.87 N E 0.88 I E 0.86 K E 0.79 N C 0.57 V C 0.86 D C 0.88 G C 0.69 E E 0.56 I E 0.73 D E 0.62 C E 0.48 S C 0.62 G C 0.48 K H 0.53 M H 0.49 F H 0.47 D C 0.57 S C 0.53 L C 0.62 D C 0.64 L E 0.53 I E 0.73 I E 0.83 A E 0.81 G E 0.78 F E 0.68 H E 0.56 E C 0.45 P C 0.50 V C 0.60 F C 0.70 A C 0.70 P C 0.72 H C 0.62 D C 0.57 K H 0.60 A H 0.65 T H 0.68 N H 0.82 T H 0.92 Q H 0.95 A H 0.95 M H 0.96 I H 0.96 A H 0.95 T H 0.95 I H 0.92 A H 0.84 S H 0.53 G C 0.80 N C 0.88 V C 0.72 H C 0.51 I E 0.72 I E 0.66 S E 0.50 H C 0.70 P C 0.76 G C 0.76 N C 0.64 P C 0.46 K H 0.47 Y H 0.44 E C 0.47 I C 0.54 D C 0.59 V C 0.57 K C 0.65 A C 0.52 V C 0.42 A H 0.52 E H 0.51 A H 0.91 A H 0.93 A H 0.94 K H 0.93 H H 0.93 Q H 0.92 V H 0.92 A H 0.91 L H 0.89 E H 0.82 I H 0.51 N C 0.84 N C 0.78 S C 0.59 S C 0.47 F E 0.41 L C 0.44 H C 0.60 S C 0.76 R C 0.82 K C 0.72 G C 0.70 S C 0.65 E C 0.67 D C 0.73 N C 0.73 C H 0.56 R H 0.94 E H 0.95 V H 0.96 A H 0.96 A H 0.96 A H 0.96 V H 0.96 R H 0.95 D H 0.92 A C 0.56 G C 0.94 G C 0.89 W E 0.63 V E 0.87 A E 0.90 L E 0.85 G E 0.58 S C 0.78 D C 0.77 S C 0.71 H C 0.75 T C 0.81 A C 0.56 F C 0.55 T C 0.52 M H 0.55 G H 0.58 E H 0.68 F H 0.91 E H 0.95 E H 0.96 C H 0.96 L H 0.96 K H 0.96 I H 0.96 L H 0.96 D H 0.95 A H 0.90 V C 0.50 D C 0.93 F C 0.93 P C 0.91 P H 0.68 E H 0.75 R H 0.75 I H 0.65 L H 0.60 N H 0.50 V C 0.53 S C 0.66 P H 0.53 R H 0.79 R H 0.85 L H 0.90 L H 0.93 N H 0.93 F H 0.94 L H 0.93 E H 0.92 S H 0.85 R H 0.51 G C 0.83 M C 0.84 A C 0.78 P C 0.68 I H 0.54 A H 0.66 E H 0.65 F C 0.50 A C 0.68 D C 0.81 L C 0.92 END