PFRMAT SS TARGET T0144 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0144.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0144.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0144.t2k.str.rdb (weight 1.53983) METHOD T0144.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0144.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0144 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0144.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 396 METHOD METHOD ============================================ METHOD Comments from T0144.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0144 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0144.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 396 METHOD METHOD ============================================ METHOD Comments from T0144.t2k.str.rdb METHOD ============================================ METHOD TARGET T0144 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0144.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 396 METHOD METHOD ============================================ METHOD Comments from T0144.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0144 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0144.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 396 METHOD METHOD ============================================ MODEL 1 M C 0.92 S C 0.79 N C 0.86 P C 0.78 K E 0.55 V E 0.83 F E 0.85 F E 0.85 D E 0.78 M E 0.75 A E 0.74 I E 0.63 A C 0.70 G C 0.74 N C 0.56 P E 0.60 A E 0.62 G E 0.60 R E 0.82 I E 0.90 V E 0.92 M E 0.91 E E 0.90 L E 0.81 Y C 0.49 A C 0.49 D C 0.56 T C 0.57 T C 0.78 P H 0.67 R H 0.85 T H 0.92 A H 0.95 E H 0.95 N H 0.94 F H 0.95 R H 0.95 A H 0.94 L H 0.91 C H 0.79 T C 0.49 G C 0.80 E C 0.77 K C 0.71 G C 0.71 V C 0.66 G C 0.77 R C 0.80 S C 0.88 G C 0.87 K C 0.73 P E 0.49 L C 0.58 H C 0.64 Y C 0.68 K C 0.75 G C 0.79 S C 0.65 T E 0.54 F E 0.64 H E 0.67 R E 0.69 V E 0.65 I C 0.51 P C 0.74 N C 0.79 F E 0.47 M E 0.74 C E 0.75 Q E 0.59 G C 0.62 G C 0.75 D C 0.79 F C 0.79 T C 0.76 A C 0.80 G C 0.82 N C 0.81 G C 0.84 T C 0.82 G C 0.84 A C 0.78 E C 0.63 S C 0.55 I C 0.54 Y C 0.67 G C 0.77 A C 0.73 K C 0.62 F C 0.64 A C 0.69 D C 0.69 E C 0.61 N C 0.64 F C 0.65 I C 0.65 K C 0.66 R C 0.69 H C 0.72 T C 0.79 G C 0.86 P C 0.80 G C 0.60 I E 0.71 L E 0.79 S E 0.75 M E 0.72 A E 0.59 N C 0.52 A C 0.72 G C 0.86 A C 0.84 G C 0.83 T C 0.81 N C 0.82 G C 0.79 S C 0.61 Q E 0.72 F E 0.86 F E 0.88 I E 0.88 C E 0.83 T E 0.62 E C 0.60 K C 0.76 T C 0.78 E C 0.66 W C 0.63 L C 0.70 D C 0.84 G C 0.87 K C 0.77 H E 0.68 V E 0.80 V E 0.86 F E 0.79 G E 0.74 K E 0.73 V E 0.61 I C 0.49 E C 0.61 G C 0.62 M H 0.63 N H 0.77 V H 0.93 V H 0.95 R H 0.95 D H 0.95 I H 0.94 E H 0.91 K H 0.78 V C 0.50 G C 0.82 S C 0.86 G C 0.84 S C 0.89 G C 0.91 K C 0.82 T C 0.63 S C 0.67 R C 0.61 P C 0.53 V E 0.72 T E 0.86 I E 0.85 A E 0.64 D C 0.51 C C 0.68 G C 0.59 Q C 0.53 L C 0.73 S C 0.92 END