Citations (SAM, SAM-T99, HMMs)
10 20 30 40 50 | | | | | 1 GSPPAQLSVHTVSWNSGHERAPTNLEELLGL.....NSGETPDVIAVAVQGFGFQTDKPQQG... 2 -TNFKRIQIAMGTWNVNGGKQFRSNLLGTTEl18sqDDGGPADIFAVGFEEMVELSAGNIVNas6 3 -TNFKRIQIAMGTWNVNGGKQFRSNLLGTTEl18sqDDGGPADIFAVGFEEMVELSAGNIVNas6 4 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPTDIFAIGFEEMVELNAGNIVSas6 5 -TNFKRIQIAVGTWNVNGGKQFRSNLLGTAEl18sqDDGSPADVFAIGFEEMVELSAGNIVNas6 6 -TNFKRIQIAMGTWNVNGGKQFRSNLLGTTEl18sqDDGGPADIFAVGFEEMVELSAGNIVNas6 7 YSKPKKIRVCVGTWNVNGGKQFRSIAKFNQTl19qdKRSKPTDIFAIGFEEMVELNAGNIVNas6 8 -TNFKRIQIAVGTWNVNGGKQFRSNLLGTAEl18sqDDGSPADVFAIGFEEMVELSAGNIVNas6 9 -TNFKRIQIAVGTWNVNGGKQFRSNLLGTAEl18sqDDGSPADVFAIGFEEMVELSAGNIVNas6 10 -TNFKRIQIAVGTWNVNGGKQFRSNLLGTAEl18yqDDGSPADVFAIGFEEMVELSAGNIVNas6 11 -TNFKRIQIAMGTWNVNGGKQFRSNLLGTTEl18sqDDGGPADIFAVGFEEMVELSAGNIVNas6 12 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPTDIFAIGFEEMVELNAGNIVSas6 13 -TNFKRIQIAVGTWNVNGGKQFRSNLLGTAEl18sqDDGSPADVFAIGFEEMVELSAGNIVNas6 14 -TNFKRIQIAVGTWNVNGGKQFRSNLLGTAEl18sqDDGSPADVFAIGFEEMVELSAGNIVNas6 15 -TNFKRIQIAVGTWNVNGGKQFRSNLLGTAEl18sqDDGSPADVFAIGFEEMVELSAGNIVNas6 16 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPTDIFAIGFEEMVELNAGNIVSas6 17 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPTDIFAIGFEEMVELNAGNIVNas6 18 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPMDIFPIGFEEMVELNAGNIVNas6 19 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPTDIFAIGFEEMVELNAGNIVNas6 20 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPTDIFAIGFEEMVELNAGNIVNas6 21 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPMDIFPIGFEEMVELNAGNIVNas6 22 -TNFKRIRIAMGTWNVNGGKQFRSNVLRTAEl18sqDDSSPADIFAVGFEEMVELSAGNIVNas6 23 -TNFKRIRIAMGTWNVNGGKQFRSNVLRTAEl18sqDDSSPADIFAVGFEEMVELSAGNIVNas6 24 YSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTl19qdKRSKPTDIFAIDFEEMVELNAGNIVNas6 25 YVNIQTFRFFVGTWNVNGQSPDSGLEPWLNC.....DPN-PPDIYCIGFQELDLSTEAFFYFesv 26 YVNIQTFRFFVGTWNVNGQSPDSGLEPWLNC.....DPN-PPDIYCIGFQELDLSTEAFFYFesv 27 YVNIQTFRFFVGTWNVNGQSPDSGLEPWLNC.....DPN-PPDIYCIGFQELDLSTEAFFYFesv 28 YVNIQTFRFFVGTWNVNGQSPDSGLEPWLNC.....DPN-PPDIYCIGFQELDLSTEAFFYFesv 29 YVNIQTFRFFVGTWNVNGQSPDSGLEPWLNC.....DPN-PPDIYCIGFQELDLSTEAFFYFesv 30 YVNIQTFRFFVGTWNVNGQSPDSGLEPWLNC.....DPN-PPDIYCIGFQELDLSTEAFFYFesv 31 YVNIQTFRFFVGTWNVNGQSPDSGLEPWLNC.....DPN-PPDIYCIGFQELDLSTEAFFYFesv 32 YTYIQNFRFFVGTYNVNGQSPKECLRPWLS-.....HSALAPDVYCVGFQELDLSKEAFFFHdtp 33 YTYIQNFRFFVGTYNVNGQSPKECLRPWLS-.....HSALAPDVYCVGFQELDLSKEAFFFHdtp 34 YTYIQNFRFFAGTYNVNGQSPKECLRLWLSN.....GIQ-APDVYCVGFQELDLSKEAFFFHdtp 35 YTYIQNFRFFVGTYNVNGQSPKECLRPWLS-.....HSALAPDVYCVGFQELDLSKEAFFFHdtp 36 YTYIQNFRFFVGTYNVNGQSPKECLRPWLS-.....HSALAPDVYCVGFQELDLSKEAFFFHdtp 37 YTHPKRLRVAIATWNVNGGKTMRSIAFKHQTl17tfQDDTPVDVFAIGFQEMVELNAGNIVSas6 38 YINTKDIKVTVATWNVAGKRPSDDLEIEDWL.....STDNPSDIYIIGFQEVVPLNAGNVFGae7 39 YINTKDIKVTVATWNVAGKRPSDDLEIEDWL.....STDNPSDIYIIGFQEVVPLNAGNVFGae7 40 YINTKDIKVTVATWNVAGKRPSDDLEIEDWL.....STDNPSDIYIIGFQEVVPLNAGNVFGae7 41 YINTKDIKVTVATWNVAGKRPSDDLEIEDWL.....STDNPSDIYIIGFQEVVPLNAGNVFGae7 42 YINTKDIKVTVATWNVAGKRPSDDLEIEDWL.....STDNPSDIYIIGFQEVVPLNAGNVFGae7 43 YIDTKAIRICAGTWNVGGRVPSSDLDIDGWL.....DTLEPADIYVLGLQEIVPLNAGNIFGme7 44 YIDTKAIRICAGTWNVGGRVPSSDLDIDGWL.....DTLEPADIYVLGLQEIVPLNAGNIFGme7 45 YIDTKAIRICAGTWNVGGRVPSSDLDIDGWL.....DTLEPADIYVLGLQEIVPLNAGNIFGme7 46 YIDTKAIRICAGTWNVGGRVPSSDLDIDGWL.....DTLEPADIYVLGLQEIVPLNAGNIFGme7 47 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 48 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 49 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 50 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 51 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 52 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 53 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 54 YTYIQNFRFFVGTYNVNGQSPKECLRPWLS-.....HSALAPDVDCVGFQELDLSKEAFFFHdtp 55 -SEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 56 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLSE... 57 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLSE... 58 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLSE... 59 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLSE... 60 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLSE... 61 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLSE... 62 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLSE... 63 -IDVQNYSIFVATWNVAGRSPPSDLNLDEWL.....HSSAPADIYVLGFQEIVPLNAGNVLGae7 64 -PEPDMITIFIGTWNMGNAPPPKKITSWFLSk10dsADYIPHDIYVIGTQE------DPLGE... 65 -IDVQNYSIFVATWNVAGRSPPSDLNLDEWL.....HSSAPADIYVLGFQEIVPLNAGNVLGae7 66 --EPDMISVFIGTWNMGSVPPPKNVTSWFTSk10evTVTIPHDIYVFGTQE------NSVGD... 67 --EPDMISVFIGTWNMGSVPPPKNVTSWFTSk10evTVTIPHDIYVFGTQE------NSVGD... 68 --EPDMISVFIGTWNMGSVPPPKNVTSWFTSk10evTVTIPHDIYVFGTQE------NSVGD... 69 --EPDMISVFIGTWNMGSVPPPKNVTSWFTSk10evTVTIPHDIYVFGTQE------NSVGD... 70 YVRPRMARVAVGTYNVNGGKHFRSIVFKDSLa24seNVDHPVDIYAIGFEEIVDLNASNIMAas6 71 --EPDMISVFIGTWNMGSVPPPKNVTSWFTSk10evTVTIPHDIYVFGTQE------NSVGD... 72 YVRPRMARVAVGTYNVNGGKHFRSIVFKDSLa24seNVDHPVDIYAIGFEEIVDLNASNIMAas6 73 --EPDMISVFIGTWNMGSVPPPKNVTSWFTSk10evTVTIPHDIYVFGTQE------NSVGD... 74 YVNPLVFRVACGTYNVNGGKHFRSVAYKDVSl25ddSNEPPVDIFAIGFQEIVDLNASNIVAas6 75 --PLDHLRVFTATWNVAGKSPPSYLNLDDWL.....HTSPPSDIYVLGFQEIVPLNAGNVLGte7 76 ------NSIFVATWNVAGRSPPEDLNLDEWL.....HSSAPADIYVLGFQEIVPLNAGNVLGae7 77 -LGPSEPRITVVTWNVGTAMPPDDVTSLLHLggg..DDSDGADMIAIGLQEVNSMLNKRLKDalf 78 YINNKEIRVCVGTWNVGGISPPSDLDIDDWI.....EINQPADIYVLGLQEIVPLNAGNILGae7 79 YINNKEIRVCVGTWNVGGISPPSDLDIDDWI.....EINQPADIYVLGLQEIVPLNAGNILGae7 80 YINNKEIRVCVGTWNVGGISPPSDLDIDDWI.....EINQPADIYVLGLQEIVPLNAGNILGae7 81 YINNKEIRVCVGTWNVGGISPPSDLDIDDWI.....EINQPADIYVLGSQEIVPLNAGNILGae7 82 ---DPGFRITVVTWNVGTAMPPDDVTSLLHLggg..HDSDGADMIAIGLQEVNSMINKRLKDalf 83 ---DPGFRITVVTWNVGTAMPPDDVTSLLHLgsg..HDNDGADMIAIGLQEVNSMINKRLKDalf 84 YINTKELKLCVGTWNAAGKVPPGDLDIADWLga...GAGEPADVYVLGFQEVVPLNAGNVFGae7 85 YSRIENLKILAGTWNVGEGRASTDSLVSWLG.....CAATGVEIVVVGLQEVEMGAGVLAMSa14 86 ---GRRLSIHVVTWNVASAAPPLDLSDLLQLn....NRNLNLDIYVIGLQELNSGIISLLSDaaf 87 ---GRRLSIHVVTWNVASAAPPLDLSDLLQLn....NRNLNLDIYVIGLQELNSGIISLLSDaaf 88 ----EPVRIFVATWNVGGKAPTAELNLDDFL.....PPDDHSDIYVLGFQEIVPLNAGNVLVie7 89 -IVYKDIIIYCATWNVNNKTCSDSNNPLRAWla...CSEKPPDIYAIGLQELDTPTKAMLNStq7 90 --THSNINLFVGTFNVNGNSRRADLSKWLFPi....GDKFKPDVVVLGLQEVIELTAGSILNad6 91 --THSNINLFVGTFNVNGNSRRADLSKWLFPi....GDKFKPDVVVLGLQEVIELTAGSILNad6 92 -TEIRELRVFLATWNVGGRTPNNDLNLEDFL.....LVEGTADLYICGFQEIVPLSAGNVLVve7 93 -TFEKDISIFAGTFNISGKIPKDDIKDWIFPksms.KEDEMADLYVIGLEEVVELTPGHMLAtd6 94 YARQDNVRILIGTWNVGQGRASHDALMSWLG.....SVTSDVGIVAVGLQEVEMGAGFLAMSa14 95 -----NYKVFVSTWNVGGIVPDDGLDMEDLLe....THKTPCDIYVLGFQEVVPLRASNVLGsd7 96 -TVYEPYHVYTATWNVNGQTSETIELPEWLA.....TTDSPPDIYAVGFQEIEWTPEKILMNetk 97 -AEPQSIKIFVGTWNVNGGKNIHNVAFRNESs17svEDEQLADIVAIGVEELVDLNASNMVKas6 98 ---IADLCIFLLTWNVGTHTPRNQDLSSLLSln7tcPDNQLPDIYVIGFQEVSTTPQVLKIFnd. 99 ------IRMFVGTWNVGGKSPHEGLDLKDWLk19inWFYRTFNILFLEFQEIVPLNAGNVLGae7 100 -AEPQSIKIFVGTWNVNGGKNIHNVAFRNESs17svEDEQLADIVAIGVEELVDLNASNMVKas6 101 -TSTSNINLLIGSFNVNGATKKVDLSKWLFPi....GEKFKPDIVVLGLQEVIELSAGSILNad6 102 -AQTDSVRILTGSWNVGQGKASHDALMSWLG.....SVASDVGILVVGLQEVEMGAGFLAMSa15 103 YTYIQNFRFFAGTYNVNGQSPKECLRLWLSN.....GIQ-APDVYCVGFQELDLSKEAFFFHdtp 104 ---DPGFRITVVTWNVGTAMPPDDVTSLLHLggg..DDSDGADMIAIGLQEVNSMLNKRLKDalf 105 ---NWNVKIYIVTWNVSTKFPENISLNKLLGle6peQDSHLPDFFVIGLQEVNAQPQNTLYNlfk 106 -ARQDSVKILIGTWNVGEGRASRGALVSWLG.....SAVSDVGIVAIGLQEVDMGAGFLAMSt14 107 ------LSVHVVTWNVASAAPTVDLSDLLQLn....NQDLNLDIYIIGLQEMNFGIISLLSDaaf 108 -SEHKNVKIFVASYNLNGCSATTKLENWLFP.....ENTPLADIYVVGFQEIVQLTPQQVISad6 109 -SEHKNVKIFVASYNLNGCSATTKLENWLFP.....ENTPLADIYVVGFQEIVQLTPQQVISad6 110 YFPDRNMALFVATWNMQGQKELPASLDEFLLpt...EADYTQDLYVIGVQE------GCSDR... 111 YFPDRNVALFVATWNMQGQKELPPSLDEFLLpa...EADYAQDLYVIGVQE------GCSDT... 112 YFPDRNMALFVATWNMQGQKELPASLDEFLLpt...EADYTQDLYVIGIQE------GCSDR... 113 ----ETYRVYVVTWNVGSRFPDNISLRHLLGl12keTNAHLPDIYALGLQEVNAQPQQQVLGlfk 114 ---ERDFSIFSSTFNANGKVPSTDEFKRLLLpfg..ERTSAYDLYVVAVQEIITLNMSHLVSss6 115 YSNFTDVSILICSWNAGASKPSDLDSDTIGAsm7miRDNGYPDIVVFGFQELVDLENKRLTAr27 116 YSNFTDVSILICSWNAGASKPSDLDSDTIGAsm7miRDNGYPDIVVFGFQELVDLENKRLTAr27 117 -CTFQDVKICVSTFNVNGRSPLSVFPTWFSQ.....KPEDIAEFYAVGLQEMDLSVGTYIIDntk 118 ------------STFSEDIVRKYGRESCFRC.....PEGLVNQSGVLSDDEEDEDDDDDDEDe.. 119 YCEFQNLKVLIMTWNAGASTPHSLRYSDSDAnf7llQTADSPDIIIFGFQELVDLEDKKATAk25 120 ---ERDFTIHVATWNVNGRKPTTITNLIGQNsd...KYENLPDMVIVGLQEVTMSAVKAVSNalt 121 -LPTREVTIFIGTWNMNGQSPPRQMNDFVLPt....ALEHVPDIIVFGTQE------SCSER... 122 -------------------------------.....--------------------------... 123 -------------------------------.....--------------------------... 124 -LPQKEITVFVGTWNMNGHSPPKQLNDFVLPa....NVEHVPDIVVMGTQE------STPDR... 125 --PPAQLSVHTVSWNSGHERAPTNLEELLGL.....NSGETPDVIAVAVQGFGFQTDKPQQG... 126 -------------------------------.....--------------------------... 127 YTTVEDLNVCVTTFNVGCKKPVLPLTSLACLts9dgAPVRPTDLIVVGLQEVDMSATALFKQe19 128 YTRPHRIRVKVGTWNVAACPGTDKDLASWFVd32hiLGRDKIGLYVLGLQEVVDLNTASQYVs11 129 --RKADLCIRIITWNMNGNVSYEDLVELV--.....GKERKFDLLVVGLQEA---------P... 130 ----RKLKVCTVTWNINEKGVKILSHLAQKIaer..GQEMDSDIFFISLQEIPSTAPLVPKTi14 131 ---DRKLKVCTVTWNINEKGVKILSHLAQKIaer..GQEMDSDIFFISLQEIPSTAPLVPKTi14 132 -------------------------------.....--------------------------... 133 -------WVCVGTWNVAGRLPPDDLDIQDWL.....DMEEPADIYVLGFQEIVPLNAGNIFGae7 134 ------WKITIFTYNLAMKASDSEAVHNMLNg....MIDDHTHLVAIGLQEVAHSETIGGAV... 135 YSRIENLKILAGTWNVGEGRASTDSLVSWLG.....CAATGVEIVVVGLQEVEMGAGVLAMSa14 136 ---KTNWKVSVTTFNCGKEFPVENSKAIVKQll9giSQLELQDLYVLGFQEVVPIWQGSFPAv14 137 --------------------LSTALPKFDLL.....RAYVDIDYEAIEYTALGAL--CFIKR... 138 --------VTVLSWNVNNREGVADTISRILG.....HGE--SDMILISLQEHF---------... 139 YTYIQNFRFFVGTYNVNGQSPKECLRPWLS-.....HSALAPDVDCVGFQELDLSKEAFFFHdtp 140 --------------------LSTALPKFDLL.....RAYVDIDYEAIEYTALGAL--CFIKR... 141 --------------------LSTALPKFDLL.....RAYVDIDYEAIEYTALGAL--CFIKR... 142 -------------------------------.....--------------------------... 143 -------------------------------.....--------------------------... 144 -------------------------------.....----------------------YFLH... 145 -------------------------------.....--------------------------... 146 -------------------------------.....-----------------------FLH... 147 -------------------------------.....--------------------------... 148 -------------------------------.....--------------------------... 149 --------VLLVTANVGSIFEEPSVMLKIWTee6stILRLDPKFIALHCQEVGGKNYEHSTRqv. 150 -------------------------------.....--------------------------... 151 -------------------------------.....--------------------------... 152 -------------------------------.....--------------------------... 60 70 80 90 100 | | | | | 1 ..PACVKNFQSLLT.....S.....KGYTKLKN...TITET..MGLTVYCLEKHLDQNTLK.... 2 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 3 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 4 nqKLWAVELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 5 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 6 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 7 nqKLWAVELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 8 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 9 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 10 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 11 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 12 nqKLWAVELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 13 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 14 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 15 nrKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 16 nqKLWAVELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 17 nqKLWAVELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 18 nqKLWAAELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 19 nqKLWAVELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 20 nqKLWAVELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 21 nqKLWAAELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 22 nkKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 23 nkKMWGEQLQKAISr....S.....HRYILLTS...AQLVG..VCLYIFVRPYHVPFIRDVai.. 24 nqKLWAVELQKTISr....D.....NKYVLLAS...EQLVG..VCLFVFIRPQHAPFIRDVav.. 25 keQEWSMAVERGLHs....K.....AKYKKVQL...VRLVG..MMLLIFARKDQCRYIRDIat.. 26 keQEWSMAVERGLHs....K.....AKYKKVQL...VRLVG..MMLLIFARKDQCRYIRDIat.. 27 keQEWSMAVERGLHs....K.....AKYKKVQL...VRLVG..MMLLIFARKDQCRYIRDIat.. 28 keQEWSMAVERGLHs....K.....AKYKKVQL...VRLVG..MMLLIFARKDQCRYIRDIat.. 29 keQEWSMAVERGLHs....K.....AKYKKVQL...VRLVG..MMLLIFARKDQCRYIRDIat.. 30 keQEWSMAVERGLHs....K.....AKYKKVQL...VRLVG..MMLLIFARKDQCRYIRDIat.. 31 keQEWSMAVERGLHs....K.....AKYKKVQL...VRLVG..MMLLIFARKDQCRYIRDIat.. 32 keEEWFKAVSESLHp....D.....AKYAKVKF...VRLVG..IMLLLYVKQEHAAYISEVea.. 33 keEEWFKAVSESLHp....D.....AKYAKVKF...VRLVG..IMLLLYVKQEHAAYISEVea.. 34 keEEWFKAVSEGLHp....D.....AKYAKVKL...IRLVG..IMLLLYVKQEHAAYISEVea.. 35 keEEWFKAVSESLHp....D.....AKYAKVKF...VRLVG..IMLLLYVKQEHAAYISEVea.. 36 keEEWFKAVSESLHp....D.....AKYAKVKF...VRLVG..IMLLLYVKQEHAAYISEVea.. 37 nqKRWSVELQKTISr....D.....HKYILVTS...EQLVG..VCLFVFLRPHHAPHVRDVav.. 38 piPKWESIIRRTLN.....Ks205sQKYVRIVS...KQMVG..IYVSVWIRRRLRRHVNNLkv.. 39 piPKWESIIRRTLN.....Ks205sQKYVRIVS...KQMVG..IYVSVWIRRRLRRHVNNLkv.. 40 piPKWESIIRRTLN.....Ks205sQKYVXIVS...KQMVG..IYVSVWIRRRLRRHVNNLkv.. 41 piPKWESIIRRTLN.....Ks205sQKYVRIVS...KQMVG..IYVSVWIRRRLRRHVNNLkv.. 42 piPKWESIIRRTLN.....Ks172sQKYVRIVS...KQMVG..IYVSVWIRRRLRRHVNNLkv.. 43 paLEWENLIRDALN.....Rv159kPSYVRIVS...KQMVG..VFLTIWVRRNLRKHISNLcv.. 44 paLEWENLIRDALN.....Rv159kPSYVRIVS...KQMVG..VFLTIWVRRNLRKHISNLcv.. 45 paLEWENLIRDALN.....Rv159kPSYVRIVS...KQMVG..VFLTIWVRRNLRKHISNLcv.. 46 paLEWENLIRDALN.....Rv159kPSYVRIVS...KQMVG..VFLTIWVRRNLRKHISNLcv.. 47 ..KEWLELLRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 48 ..KEWLELLRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 49 ..KEWLELLRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 50 ..KEWLELLRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 51 ..KEWLELLRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 52 ..KEWLELLRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 53 ..KEWLELLRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 54 keEEWFKAVSESLHp....D.....AKYAKVKF...VRLVG..IMLLLYVKQEHAAYISEVea.. 55 ..KEWLEILRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 56 ..KEWLEILKHSLQeit..S.....VTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 57 ..KEWLEILKHSLQeit..S.....VTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 58 ..KEWLEILKHSLQeit..S.....VTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 59 ..KEWLEILKHSLQeit..S.....VTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 60 ..KEWLEILKHSLQeit..S.....VTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 61 ..KEWLEILKHSLQeit..S.....VTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 62 ..KEWLEILKHSLQeit..S.....VTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 63 paQKWLSLIRKTLN.....Nr184sSQYCLVAS...KQMVG..VFLTIWVKSELREHVKNMkv.. 64 ..KEWLELLRHSLQevt..S.....MTFKTVAI...HTLWN..IRIVVLAKPEHENRISHIct.. 65 paQKWLSLIRKTLN.....Nr184sSQYCLVAS...KQMVG..VFLTIWVKSELREHVKNMkv.. 66 ..REWLDLLRGGLKelt..D.....LDYRPIAM...QSLWN..IKVAVLVKPEHENRISHVst.. 67 ..REWLDLLRGGLKelt..D.....LDYRPIAM...QSLWN..IKVAVLVKPEHENRISHVst.. 68 ..REWLDLLRGGLKelt..D.....LDYRPIAM...QSLWN..IKVAVLVKPEHENRISHVst.. 69 ..REWLDLLRGGLKelt..D.....LDYRPIAM...QSLWN..IKVAVLVKPEHENRISHVst.. 70 naKLWAEELQKTISr....D.....NDYVLLTY...QQLVG..VCLYIYIRPEHAPHIRDVai.. 71 ..REWLDLLRGGLKelt..D.....LDYRPIAM...QSLWN..IKVAVLVKPEHENRISHVst.. 72 naKLWAEELQKTISr....D.....NDYVLLTY...QQLVG..VCLYIYIRPEHAPHIRDVai.. 73 ..REWLDLLRGGLKelt..D.....LDYRPIAM...QSIWN..IKVAVLVKPEHENRISHVst.. 74 naKAWAEELQKVVSr....D.....REYVLLTY...QQLVG..VCLYIYIRPQHAQYIRDVai.. 75 paRKWVSLIRRTLN.....Sl117kSKYCLVAS...KQMVG..IFLTVWVKSDLRDSVNNLkv.. 76 paKKWHSLIRKTLN.....Nl162sSQYCLVAS...KQMVG..IFLTIWVKSELREHVKNMkv.. 77 t.DQWSELFMDALG.....P.....FNFVLVSS...VRMQG..VILLLFAKYYHLPFLRDVqt.. 78 pvAKWEEVIREALN.....Rv207rPAYVRLVS...KQMVG..ILLTIWVKRSLRKHIQNVrv.. 79 pvAKWEEVIREALN.....Rv207rPAYVRLVS...KQMVG..ILLTIWVKRSLRKHIQNVrv.. 80 pvAKWEEVIREALN.....Rv207rPAYVRLVS...KQMVG..ILLTIWVKRSLRKHIQNVrv.. 81 pvAKWEEVIREALN.....Rv207rPAYVRLVS...KQMVG..ILLTIWVKRSLRKHIQNVrv.. 82 t.DQWSELFMDALG.....P.....FNFVLVST...VRMQG..VILLLFAKYYHLPFLRDVqt.. 83 t.DQWSELFMDALG.....P.....FNFVLVST...VRMQG..VILLLFAKYYHLPFLRDVqt.. 84 paQAWEELIRSALR.....Ra180rSPYVRIVS...KQMVG..VFLTVWVRRGLRRCVHNVgv.. 85 lgQWWLDMIGKTLDe....G.....SSFVRVGS...RQLAG..LLICVWVRHDLKPHVGDVda.. 86 n.DSWSSFLMDVLS.....P.....LSFIKVSH...VRMQG..ILLLVFAKYQHLPYIQILst.. 87 n.DSWSSFLMDVLS.....P.....LSFIKVSH...VRMQG..ILLLVFAKYQHLPYIQILst.. 88 paARWLVLINQALN.....Rp129eLKYNLIAC...KQMVG..IFVMVWVKKELVQHIGHLrt.. 89 ieKQWIDKMMDSVHp....D.....VEYEILMS...HRLVA..TMLTVIVRKQLRQHIIRCrp.. 90 ksSFWETMVTDCLNqy...E.....EKYLLLRV...EQMSS..LLILFFARSDRAYNIKEVgg.. 91 ksSFWETMVTDCLNqy...E.....EKYLLLRV...EQMSS..LLILFFARSDRAYNIKEVgg.. 92 paAKWLALISQALN.....Kp116qMSYRLIAS...KQMVG..LFLSVWARRELIPHISHLrl.. 93 vrQFWEKKILTLLNgpgr.K.....KKYIRLWS...TQLGG..ILLLLFMNETEYSKVKHIeg.. 94 vgQWWIDAIGKALDe....K.....NTFERMGS...RQLAG..LLISLWARKDIRTHVGDLdv.. 95 vsTKWNSLIRDALN.....Kr20isQDFRCIIS...KQMVG..ILITVWVRGDLWPYIRYPsv.. 96 idRTWVDKVMSGLHk....G.....AIYTELAS...VRLVG..MMLTVAVKSTIYPKINDClt.. 97 nqRMWCESIRKTLSe....K.....APFVLIGS...EQLVG..VCLFLFARPRVSPYLKDFav.. 98 ..DPWVLKIADSLS.....D.....HQFVKVDS...KQLQG..ILITMFAQHKHIPHMKEIet.. 99 paAKWLSLIREALN.....Nt22ppRGYSLAAS...KQMVG..IFLCVWVRDDLRKRITNLkv.. 100 nqRMWCESIRKTLSe....K.....APFVLIGS...EQLVG..VCLFLFARPRVSPYLKDFav.. 101 ksSFWENLVGDCLNqy...D.....DKYLLLRV...EQMTS..LLILFFVKADKAKYVKQVeg.. 102 igQYWIDTIGKTLDe....K.....AVFERMGS...RQLAG..LLISLWVRKNLRTHVGDIdv.. 103 keEEWFKAVSEGLHp....D.....AKYAKVKL...IRLVG..IMLLLYVKQEHAAYISEVea.. 104 t.DQWSELFMDALG.....Pf35lg-LCGWVSS...VRMQG..VILLLFAKYYHLPFLRDVqt.. 105 d.DLWTQKFKEVLK.....E.....RDYVVIKT...EQMQG..LLLSVFARRKHLLHLRQVet.. 106 vgQWWLDAIGNALDe....R.....NTFERMGS...RQLAG..LLISLWVRKSIRTHVGDLdv.. 107 e.DPWSSLFMDMLS.....P.....LNFVKISQ...VRMQG..LLLLVFAKYQHLPYIQIIst.. 108 krREWESCVKRLLNgkctsG.....PGYVQLRS...GQLVG..TALMIFCKESCLPSIKNVeg.. 109 krREWESCVKRLLNgkctsG.....PGYVQLRS...GQLVG..TALMIFCKESCLPSIKNVeg.. 110 ..REWETRLQETLG.....P.....-QYVLLSS...AAHGV..LYMSLFIRRDLIWFCSEVey.. 111 ..REWETRLQETLG.....P.....-HYVLLSS...AAHGV..LYMSLFIRRDLIWFCSEVec.. 112 ..REWETRLQETLG.....P.....-QYVLLSS...AAHGV..LYMSLFIRRDLIWFCSEVey.. 113 e.DPWTHKAKELLR.....N.....YDYVAVKT...EQMQG..LLLSMFVRRQHVEHLQDIea.. 114 klRIWEEKILMILNsrds.N.....NKYMLISS...IQMAG..VFLGVFIRKDDHLVVSKVtk.. 115 wrEKLESEMMRVSS.....N.....DDYQVLVC...ENLVG..LFSCVFVKNKLQSKIRMLqs.. 116 wrEKLESEMMRVSS.....N.....DDYQVLVC...ENLVG..LFSCVFVKNKLQSKIRMLqs.. 117 kmEGWVDAIHCSLPgg...R.....TQFNVVGS...MRLVG..IFVIVFQAVNSKVRVSDVnvky 118 ..DEGGGKVASLVSnqm..T.....MKYGLVAS...KQMVG..IFLTVWMRKELIQHVSHLri.. 119 wrDFLIRSLDDYMQ.....G.....DLYHLLHT...SPLVG..LFTCIFVKADLRGRISNLss.. 120 g.ELWSETMEKTLK.....S.....-NYQKVKS...VALLG..IVLNVFLKLNTAWALKNAav.. 121 ..FEWEVTLQETLG.....P.....-SHILLHS...TSLGT..LHLAAFIRRDLIWFCSEPed.. 122 ..---------VLS.....P.....LSFIKVSH...VRMQG..ILLLVFAKYQHLPYIQILst.. 123 ..---------VLS.....P.....LSFIKVSH...VRMQG..ILLLVFAKYQHLPYIQILst.. 124 ..FEWEVTIQETLG.....P.....-SHVLFHA...TTLGT..LHLAVYMRRDLIWYCSVPed.. 125 ..PACVKNFQSLLT.....S.....KGYTKLKN...TITET..MGLTVYCLEKHLDQNTLK.... 126 ..------------.....-.....--------...-----..------------------.... 127 as------------.....-r15gaSPYYAFPP...KQLVG..LLLCVFIRRPLLSAVSESst.. 128 vtQKWKTALDTALP.....-.....PGYKLVAS...EHMTG..LLLLIYASPEVAPTISNVst.. 129 ..KANVDQLLQTAS.....S.....PTHELLGK...AKLQS..VQLYLFGPKNSHTLVKELkae. 130 fhEEALRILEPVLN.....-.....-GHRLYLS...HRAWS..QMVIVFIRQKHLRYAIREf19v 131 fhEEALRILEPVLN.....-.....-GHRLYLS...HRAWS..QMVIVFIRQKHLRYAIREf19v 132 ..------------.....-.....--------...-----..------------------.... 133 pvAMWEHIIRETLN.....Ki187rPYFVRIIS...KQMVG..VFISIWVRRSLRKHIQNLkv.. 134 ..LTWATTIASWMNt....N.....GRMVLLAK...TFQAT..NQVLIFGRKQLIGQIKRIdy.. 135 lgQWWLDMIGKTLD.....E.....AGASFGVT...MPRGG..NAL---------------.... 136 avNCLNEKVSATQG.....D.....EQYSCLGV...NSLGA..ITIIVLYNNNALKVKDDIlk.. 137 ..SLWSNVSQFNFH.....T.....KKYEQLTSpkeVVTHG..LENYPYVVKHKFPKDFWP.... 138 ..DFYSGVVRSVLKm....Y.....PSYKMVSA...DRVLG..LWSIVLSKERHSTTVMKI.... 139 keEEWFKAVSESLHp....D.....AKYAKVKF...VRLVG..IMLLLYVKQEHAAYISEVea.. 140 ..SLWSNVSQFNFH.....T.....KKYEQLTSpkeVVTHG..LENYPYVVKHKFPKDFWP.... 141 ..SLWSNVSQFNFH.....T.....KKYEQLTSpkeVVTHG..LENYPYVVKHKFPKDFWP.... 142 ..------------.....-.....--------...-----..------------------.... 143 ..------------.....-.....--------...-----..------------------.... 144 ..ESLKNIYQFDFK.....A.....KKYKKVTG...KEIYSdtLESTPMLEKEKFPQDYFP.... 145 ..-SLKNIYQFDFK.....A.....KKYKKVTG...KEIYSdtLESTPMLEKEKFPQDYFP.... 146 ..ESLKNIYQFDFK.....A.....KKYRKVAG...KEIYSdtLESTPMLEKEKFPQDYFP.... 147 ..ESLKNIYQFDFK.....A.....KKYRKVAG...KEIYSdtLESTPMLEKEKFPQDYFP.... 148 ..------------.....-.....--------...-----..------------------.... 149 ..---EDFVRLLMS.....Se46qeCTFISVNG...KEVHS..GNIEAVTTKEKAKFPQEFfp.. 150 ..------------.....-.....--------...-----..------------------.... 151 ..------------.....-.....--------...-----..-----------------V.... 152 ..------------.....-.....--------...-----..------------------.... 110 120 130 140 | | | | 1 .NETIIVTVDD....QK.KSGGIVTSFTI.....YNKRFSFTTSRMSD..EDVT.....STN..T 2 .DTVKTGMGGK....AG.NKGAVGIRFQF.....HSTSFCFICSHLTA..GQSQ.....VKE..R 3 .DTVKTGMGGK....AG.NKGAVGIRFQF.....HSTSFCFICSHLTA..GQSQ.....VKE..R 4 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 5 .DTVKTGMGGK....AG.NKGAVGIRFQL.....HSTSFCFVCSHLTA..GQSQ.....VKE..R 6 .DTVKTGMGGK....AG.NKGAVGIRFQF.....HSTSFCFICSHLTA..GQSQ.....VKE..R 7 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 8 .DTVKTGMGGK....AG.NKGAVGIRFQL.....HSTSFCFVCSHLTA..GQSQ.....VKE..R 9 .DTVKTGMGGK....AG.NKGAVGIRFQL.....HSTSFCFVCSHLTA..GQSQ.....VKE..R 10 .DTVKTGMGGK....AG.NKGAVGIRFQL.....HSTSFCFVCSHLTA..GQSQ.....VKE..R 11 .DTVKTGMGGK....AG.NKGAVGIRFQF.....HSTSFCFICSHLTA..GQSQ.....VKE..R 12 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 13 .DTVKTGMGGK....AG.NKGAVGIRFQL.....HSTSFCFVCSHLTA..GQSQ.....VKE..R 14 .DTVKTGMGGK....AG.NKGAVGIRFQL.....HSTSFCFVCSHLTA..GQSQ.....VKE..R 15 .DTVKTGMGGK....AG.NKGAVGIRFQL.....HSTSFCFVCSHLTA..GQSQ.....VKE..R 16 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 17 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 18 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 19 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 20 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 21 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 22 .DTVKTGMGGK....AG.NKGAVGIRFQF.....HSTSFCFICSHLTA..GQSQ.....VKE..R 23 .DTVKTGMGGK....AG.NKGAVGIRFQF.....HSTSFCFICSHLTA..GQSQ.....VKE..R 24 .DTVKTGMGGA....TG.NKGAVAIRMLF.....HTTSLCFVCSHFAA..GQSQ.....VKE..R 25 .ETVGTGIMGK....MG.NKGGVAVRFVF.....HNTTFCIVNSHLAA..HVED.....FER..R 26 .ETVGTGIMGK....MG.NKGGVAVRFVF.....HNTTFCIVNSHLAA..HVED.....FER..R 27 .ETVGTGIMGK....MG.NKGGVAVRFVF.....HNTTFCIVNSHLAA..HVED.....FER..R 28 .ETVGTGIMGK....MG.NKGGVAVRFVF.....HNTTFCIVNSHLAA..HVED.....FER..R 29 .ETVGTGIMGK....MG.NKGGVAVRFVF.....HNTTFCIVNSHLAA..HVED.....FER..R 30 .ETVGTGIMGK....MG.NKGGVAVRFVF.....HNTTFCIVNSHLAA..HVED.....FER..R 31 .ETVGTGIMGK....MG.NKGGVAVRFVF.....HNTTFCIVNSHLAA..HVED.....FER..R 32 .ETVGTGIMGR....MG.NKGGVAIRFQL.....HNTSICVVNSHLAA..HTEE.....YER..R 33 .ETVGTGIMGR....MG.NKGGVAIRFQL.....HNTSICVVNSHLAA..HTEE.....YER..R 34 .ETVGTGIMGR....MG.NKGGVAIRFQF.....HNTSICVVNSHLAA..HIEE.....YER..R 35 .ETVGTGIMGR....MG.NKGGVAIRFQL.....HNTSICVVNSHLAA..HTEE.....YER..R 36 .ETVGTGIMGR....MG.NKGGVAIRFQL.....HNTSICVVNSHLAA..HTEE.....YER..R 37 .DTVKTGMGGA....TG.NKGGVAIRLQM.....YSSSLCFVCSHFAA..GQSH.....TRE..R 38 .SPVGVGLMGY....MG.NKGSVSISMTL.....YQSRMCFVCSHLTS..GHKD.....GAEqrR 39 .SPVGVGLMGY....MG.NKGSVSISMTL.....YQSRMCFVCSHLTS..GHKD.....GAEqrR 40 .SPVGVGLMGY....MG.NKGSVSISMTL.....YQSRMCFVCSHLTS..GHKD.....GAEqrR 41 .SPVGVGLMGY....MG.NKGSVSISMTL.....YQSRMCFVCSHLTS..GHKD.....GAEqrR 42 .SPVGVGLMGY....MG.NKGSVSISMTL.....YQSRMCFVCSHLTS..GHKD.....GAEqrR 43 .STVGVGIMGY....IG.NKGSVSVSMSI.....YQTPFCFLCTHLSS..GEKD.....TDQekR 44 .STVGVGIMGY....IG.NKGSVSVSMSI.....YQTPFCFLCTHLSS..GEKD.....TDQekR 45 .STVGVGIMGY....IG.NKGSVSVSMSI.....YQTPFCFLCTHLSS..GEKD.....TDQekR 46 .STVGVGIMGY....IG.NKGSVSVSMSI.....YQTPFCFLCTHLSS..GEKD.....TDQekR 47 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 48 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 49 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 50 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 51 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 52 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 53 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 54 .ETVGTGFMGRmsfqQG.NKGGVAIRFQL.....HNTSICVVNSHLAA..HTEE.....YER..R 55 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 56 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 57 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 58 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 59 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 60 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 61 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 62 .DNVKTGIANT....LG.NKGAVGVSFMF.....NGTSLGFVNSHLTS..GSEK.....KLR..R 63 .SCVGRGLMGY....LG.NKGSISISMLL.....HQTSFCFVCTHLTS..GQKE.....GDElkR 64 .DNVKTGIANT....LG.NKGAAGVSFMF.....IGTSLGFVNSHLTS..GSEK.....KLR..R 65 .SCVGRGLMGY....LG.NKGSISISMLL.....HQTSFCFVCTHLTS..GQKE.....GDElkR 66 .SSVKTGIANT....LG.NKGAVGVSFMF.....NGTSFGFVNCHLTS..GNEK.....TAR..R 67 .SSVKTGIANT....LG.NKGAVGVSFMF.....NGTSFGFVNCHLTS..GNEK.....TAR..R 68 .SSVKTGIANT....LG.NKGAVGVSFMF.....NGTSFGFVNCHLTS..GNEK.....TTR..R 69 .SSVKTGIANT....LG.NKGAVGVSFMF.....NGTSFGFVNCHLTS..GNEK.....TTR..R 70 .DCVKTGLGGA....TG.NKGACAIRFVL.....HGTSMCFVCAHFAA..GQSQ.....VAE..R 71 .SSVKTGIANT....LG.NKGAVGVSFMF.....NGTSFGFVNCHLTS..GNEK.....TTR..R 72 .DCVKTGLGGA....TG.NKGACAIRFVL.....HGTSMCFVCAHFAA..GQSQ.....VAE..R 73 .SSVKTGIANT....LG.NKGAVGVSFMF.....NGTSFGFVNCHLTS..GNEK.....TTR..R 74 .DCVKTGLGGA....TG.NKGAAAIRFVL.....HGTSICFVCAHFAA..GQSQ.....VAE..R 75 .SCVGRGLMGY....LG.NKGSISISMSV.....HQTSFCFVCSHLTS..GQKE.....GDElrR 76 .SCVGRGLMGY....LG.NKGSISISMLL.....HQTSFCFVCTHLTS..GQKE.....GDElrR 77 .DCTRTGLGGY....WG.NKGGVSVRLAA.....FGHMLCFLNCHLPA..HMDK.....AEQ..R 78 .STVGVGVMGY....IG.NKGAVSVSMSI.....NQTFFCFINTHLTA..GERE.....VDQikR 79 .STVGVGVMGY....IG.NKGAVSVSMSI.....NQTFFCFINTHLTA..GERE.....VDQikR 80 .STVGVGVMGY....IG.NKGAVSVSMSI.....NQTFFCFINTHLTA..GERE.....VDQikR 81 .STVGVGVMGY....IG.NKGAVSVSMSI.....NQTFFCFINTHLTA..GERE.....VDQikR 82 .DCTRTGLGGY....WG.NKGGVSVRLAA.....FGHMLCFLNCHLPA..HMDK.....AEQ..R 83 .DCTRTGLGGY....WG.NKGGVSVRLAA.....FGHMLCFLNCHLPA..HMDK.....AEQ..R 84 .STVGVGAMGY....IG.NKGAVSVSMSV.....YQTMFCFVCTHLAA..GEKPad...LHK..R 85 .AAVPCGFGRA....IG.NKGAVGVRLRM.....YDRVLCFVNCHFAA..HLEA.....VNR..R 86 .KSTPTGLFGY....WG.NKGGVNICLKL.....YGYYVSIINCHLPP..HISN.....NYQ..R 87 .KSTPTGLFGY....WG.NKGGVNICLKL.....YGYYVSIINCHLPP..HISN.....NYQ..R 88 .SCIGRGILGC....LG.NKGCISVSMTL.....HQTSFCFICSHLAS..GQKE.....GDEfrR 89 .KSVARGIFNT....LG.NKGGVAISLQL.....NEGNICFVNSHLAA..HMGY.....VEE..R 90 .STKKTGFGGI....TG.NKGAVAIRFDY.....GATSFCFVNTHLSA..GASN.....IDE..R 91 .STKKTGFGGI....TG.NKGAVAIRFDY.....GATSFCFVNTHLSA..GASN.....IDE..R 92 .DSVGRGIMGR....LG.NKGCIAISMSL.....HQTSFCFVCSHLAS..GEKE.....GDElrR 93 .DVKKTGFGGM....AS.NKGAVAVSFKY.....SATRFCVLVSHLAA..GLEN.....VEQ..R 94 .AAVPCGFGRA....IG.NKGGVGLRIRV.....YDRIMCFVNCHLAA..HLEA.....VNR..R 95 .SCVGCGIMGC....LG.NKGSVSVRFQL.....HETTFCFVCSHLAS..GGRD.....RDErqR 96 .AAVGTGTLK-....WG.NKGGVGVSFKL.....NEALFCFVNTHLAA..HTQE.....VER..R 97 .ASVKTGMGGA....TG.NKGSVAFRIVV.....FSTSICFICSHFAA..GQNE.....IRD..R 98 .EATRTGLGGL....WG.NKGAVSIRLSL.....YGTGVAFVCSHLAA..HDEK.....LKE..R 99 .SCVGRGIMGY....LG.NKGSVSISMSL.....HETSLCFVCTHLTS..GEKE.....GDElrR 100 .ASVKTGMGGA....TG.NKGSVAFRIVV.....FSTSICFICSHFAA..GQNE.....IRD..R 101 .ATKKTGFRGM....AG.NKGAVSIRFEY.....GATSFCFVNSHLAA..GATN.....VEE..R 102 .AAVPCGFGRA....IG.NKGGVGLRIRV.....FDRIMCFINCHLAA..HLEA.....VNR..R 103 .ETVGTGIMGR....MG.NKGGVAIRFQF.....HNTSICVVNSHLAA..HIEE.....YER..R 104 .DCTRTGLGGY....WG.NKGGVSVRLAA.....FGHMLCFLNCHLPA..HMDK.....AEQ..R 105 .EYTRTGLGGI....WG.NKGAVSIRMNV.....YGSSICLVNAHLAA..HDHM.....LEE..R 106 .AAVPCGFGRA....IG.NKGGVGLRIRV.....YDRIMCFVNCHLAA..HLEA.....VTR..R 107 .KSTPTGLYGY....WG.NKGGVNVCLKL.....YGYYVSIINCHLPP..HMYN.....NDQ..R 108 .TVKKTGLGGV....SG.NKGAVAIRFDY.....EDTGLCFITSHLAA..GYTN.....YDE..R 109 .TVKKTGLGGV....SG.NKGAVAIRFDY.....EDTGLCFITSHLAA..GYTN.....YDE..R 110 .STVTTRIVSQ....IK.TKGALGVSFTF.....FGTSFLFITSHFTS..GDGK.....VAE..R 111 .STVTTRIVSQ....IK.TKGALGISFTF.....FGTSFLFITSHFTS..GDGK.....VAE..R 112 .STVTTRIVSQ....IK.TKGALGVSFTF.....FGTSFLFITSHFTS..GDGK.....VAE..R 113 .EFTRTGFGGI....WG.NKGAVSVRFTL.....YGCGLAFVVAHLTA..HDHM.....MDE..R 114 .TTRKTGFGGF....SA.NKGAVAIEMNV.....CDSDFCFVSSHFAP..KVNN.....ISE..R 115 .TTVKTGLGGL....HG.NKGAIVVRFLV.....DDTSYCIVNCHLAA..GQSN.....KAA..R 116 .TTVKTGLGGL....HG.NKGAIVVRFLV.....DDTSYCIVNCHLAA..GQSN.....KAA..R 117 vATGISVLVNK....LG.NKGGTAVSMKM.....NDTWVCFVNAHFAA..GNNE.....LER..R 118 .SSVTRGIMGC....LG.NKGCIAVSLQL.....YKTSFCFICSHLAS..GERE.....GDErrR 119 .NEVKRGLGGL....HG.NKGAIVVRFLV.....DDTSLCFINCHLAA..GQSG.....ANQ..R 120 .DEVTTGMVGL....YG.NKGGVIMKSQL.....HDLMFCIVNAHFHA..HDKG.....QES..R 121 .ACLSVRPGTA....FR.TKGAVAISFCL.....FGTSFLFVTSHLTA..HQQK.....VKE..R 122 .KSTPTGLFGY....WG.NKGGVNICLKL.....YGYYVSIINCHLPP..HISN.....NYQ..R 123 .KSTPTGLFGY....WG.NKGGVNICLKL.....YGYYVSIINCHLPP..HISN.....NYQ..R 124 .ASMSVRTGSA....FR.TKGAVAISFCL.....FGTSMLFVTSHLTA..HQQK.....VKE..R 125 .NETIIVTVDD....QK.KSGGIVTSFTI.....YNKRFSFTTSRMSD..EDVT.....STN..T 126 .----------....-G.NKGAVGIRFQL.....HSTSFCFVCSHLTA..GQSQ.....VKE..R 127 .ATVATGALGS....MG.NKGAVGFHLVL.....HRTSICIITAHLAA..GQSN.....VSK..R 128 .VSVGTGLLGY....MG.NKGAVVTRIILg....ESTRLVFVNCHLAS..GIEGty...NER..R 129 .RYSVGGCGGL....IGrKKGAVAIRINY.....DDIKMVFISCHLSA..HAKK.....VDQ..R 130 sFIASGAMAKP....VR.TKGAIAVCLRL.....YQRFIVLIGCHLSH..--AT.....PQQ..R 131 sFIASGAMAKP....VR.TKGAIAVCLRL.....YQRFIVLIGCHLSH..--AT.....PQQ..R 132 .-----GLFGY....WG.NKGGVNICLKL.....YGYYVSIINCHLPP..HISN.....NYQ..R 133 .STVGVGAM--....--.--GYIAPSFVH.....FGRTISCTFTM---..----.....---..- 134 .RFQRNTMGGL....TG.HKGSIGVRLQLa....SPYSIVFVDSHFIH..GPEN.....YGK..R 135 .----------....--.-----------.....--------------..G---.....---..- 136 .RNGKCGWFG-....TH.LKGGTLISFQMtr6eeNWERFSYICAHLNAneGVNN.....RNQ..R 137 .SIK-------....WG.RKGYMQTRWKI.....ENKVFDFVNAHLFH..DESNl11lySQN..R 138 .GLGFLGFI--....--.NKGACVTRI--.....-SNGVMFISCHLSA..HQEN.....SKK..R 139 .ETVGTGFMGRmsfqQG.NKGGVAIRFQL.....HNTSICVVNSHLAA..HTEE.....YER..R 140 .SIK-------....WG.RKGYMQTRWKI.....ENKVFDFVNAHLFH..DESNl11lySQN..R 141 .SIK-------....WG.RKGYMQTRWKI.....ENKVFDFVNAHLFH..DESNl11lySQN..R 142 .----------....--.-----------.....--------------..----.....-EE..R 143 .----------....--.-----------.....--------------..----.....---..- 144 .ECK-------....WS.RKGFVRTRWCV.....ADCAFDLVNIHLFH..DASNl11vySGI..R 145 .ECK-------....WS.RKGFIRTRWCI.....ADCAFDLVNIHLFH..DASNl11vySGV..R 146 .ECK-------....WS.RKGFIRTRWCI.....ADCAFDLVNIHLFH..DASNl11vySGI..R 147 .ECK-------....WS.RKGFIRTRWCI.....ADCAFDLVNIHLFH..DASNl11vySGI..R 148 .----------....--.-----------.....--------------..----.....---..- 149 .EC-------K....WS.RKGFLRTRWSI.....SGTVFDLINIHLFH..DASNf11vySKT..R 150 .----------....--.--------VVI.....ADCAFDLVNIHLFH..DASNl11vySGI..R 151 .QMVKKRLHPD....--.-------EVVI.....ADCAFDLVNIHLFH..DASNl11vySGI..R 152 .----------....--.-----------.....--------------..----.....---..- 150 160 170 180 190 | | | | | 1 KYAYDTRLDYSKK.....DDPSDFLFWIGDLNVRV.....ET.....NATHAKSLV...DQN... 2 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 3 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 4 NEDFIEIARKLSFpmgrmLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 5 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 6 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 7 NEDFVEIARKLSFpmgrmLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 8 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 9 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 10 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 11 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 12 NEDFIEIARKLSFpmgrmLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 13 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 14 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 15 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 16 NEDFIEIARKLSFpmgrmLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 17 NEDFVEIARKLSFpmgrmLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 18 NDDFLEIARKLSFpmgrlLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 19 NEDFVEIARKLSFpmgrmLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 20 NEDFVEIARKLSFpmgrmLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 21 NDDFLEIARKLSFpmgrlLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 22 NEDYKEITQKLCFpmgrnVFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 23 NEDYKEITQKLCFpmgrnVFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 24 NEDFVEIARKLSFpmgrmLFSHDYVFWCGDFNYRI.....DL.....PNEEVKELI...RQQ... 25 NQDYKDICARMSFv11lnIMKHEVVIWLGDLNYRLc....MP.....DANEVKSLI...NKK... 26 NQDYKDICARMSFv11lnIMKHEVVIWLGDLNYRLc....MP.....DANEVKSLI...NKK... 27 NQDYKDICARMSFv11lnIMKHEVVIWLGDLNYRLc....MP.....DANEVKSLI...NKK... 28 NQDYKDICARMSFv11lnIMKHEVVIWLGDLNYRLc....MP.....DANEVKSLI...NKK... 29 NQDYKDICARMSFv11lnIMKHEVVIWLGDLNYRLc....MP.....DANEVKSLI...NKK... 30 NQDYKDICARMSFv11lnIMKHEVVIWLGDLNYRLc....MP.....DANEVKSLI...NKK... 31 NQDYKDICARMSFv11lnIMKHEVVIWLGDLNYRLc....MP.....DANEVKSLI...NKK... 32 NQDYRDICSRMQFp11ltINKHDVILWLGDLNYRIe....EL.....DVGKVKKLV...EEK... 33 NQDYRDICSRMQFp11ltINKHDVILWLGDLNYRIe....EL.....DVGKVKKLV...EEK... 34 NQDYKDICSRMQFc11ltISNHDVILWLGDLNYRIe....EL.....DVEKVKKLI...EEK... 35 NQDYRDICSRMQFp11ltINKHDVILWLGDLNYRIe....EL.....DVGKVKKLV...EEK... 36 NQDYRDICSRMQFp11ltINKHDVILWLGDLNYRIe....EL.....DVGKVKKLV...EEK... 37 NEDYAEIARKISFpmgrgLFSHDYVFWCGDFNYRI.....DL.....SGDEVKELV...RQK... 38 NADVYEIIRRTRFa11rtIPCHDQVFWFGDLNYRL.....NM.....SDGEVRKLV...SQK... 39 NADVYEIIRRTRFa11rtIPCHDQVFWFGDLNYRL.....NM.....SDGEVRKLV...SQK... 40 NADVYEIIRRTRFa11rtIPCHDQVFWFGDLNYRL.....NM.....SDGEVRKLV...SQK... 41 NADVYEIIRRTRFa11rtIPCHDQVFWFGDLNYRL.....NM.....SDGEVRKLV...SQK... 42 NADVYEIIRRTRFa11rtIPCHDQVFWFGDLNYRL.....NM.....SDGEVRKLV...SQK... 43 NDDVREIHRRTQFl13rsICNHERIIWLGDLNYRI.....NL.....SYEKTHELI...ARK... 44 NDDVREIHRRTQFl13rsICNHERIIWLGDLNYRI.....NL.....SYEKTHELI...ARK... 45 NDDVREIHRRTQFl13rsICNHERIIWLGDLNYRI.....NL.....SYEKTHELI...ARK... 46 NDDVREIHRRTQFl13rsICNHERIIWLGDLNYRI.....NL.....SYEKTHELI...ARK... 47 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 48 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 49 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 50 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 51 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 52 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 53 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 54 NQDYRDICSRMQFp11ltINKHDVILWLGDLNYRIe....EL.....DVGKVKKLV...EEK... 55 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 56 NQNYMNILRFLALg10niTHRFTHLFWFGDLNYRVdlp..TW.....EAETIIQKI...KQQ... 57 NQNYMNILRFLALg10niTHRFTHLFWFGDLNYRVdlp..TW.....EAETIIQKI...KQQ... 58 NQNYMNILRFLALg10niTHRFTHLFWFGDLNYRVdlp..TW.....EAETIIQKI...KQQ... 59 NQNYMNILRFLALg10niTHRFTHLFWFGDLNYRVdlp..TW.....EAETIIQKI...KQQ... 60 NQNYMNILRFLALg10niTHRFTHLFWFGDLNYRVdlp..TW.....EAETIIQKI...KQQ... 61 NQNYMNILRFLALg10niTHRFTHLFWFGDLNYRVdlp..TW.....EAETIIQKI...KQQ... 62 NQNYMNILRFLALg10niTHRFTHLFWFGDLNYRVdlp..TW.....EAETIIQKI...KQQ... 63 NSDVMEILKKTRFp14enILQHDRVIWLGDLNYRI.....AL.....SYRSAKALV...EMQ... 64 NQNYMNILRFLALg10niTHRFTHLFWLGDLNYRVelp..TW.....EAEAIIQKI...KQQ... 65 NSDVMEILKKTRFp14enILQHDRVIWLGDLNYRI.....AL.....SYRSAKALV...EMQ... 66 NQNYLDILRLLSLg10diSLRFTHLFWFGDLNYRL.....DM.....DIQEILNYI...SRK... 67 NQNYLDILRLLSLg10diSLRFTHLFWFGDLNYRL.....DM.....DIQEILNYI...SRK... 68 NQNYLDILRLLSLg10diSLRFTHLFWFGDLNYRL.....DM.....DIQEILNYI...SRR... 69 NQNYLDILRLLSLg10diSLRFTHLFWFGDLNYRL.....DM.....DIQEILNYI...SRR... 70 NADYAEITRKLAFpmgrtLKSHDWVFWCGDFNYRI.....DM.....EKDELKECV...RNG... 71 NQNYLDILRLLSLg10diSLRFTHLFWFGDLNYRL.....DM.....DIQEILNYI...SRR... 72 NADYAEITRKLAFpmgrtLKSHDWVFWCGDFNYRI.....DM.....EKDELKECV...RNG... 73 NQNYLDILRLLSLg10diSLRFTHLFWFGDLNYRL.....DM.....DIQEILNYI...SRR... 74 NADYAEITRKIAFpmgrsLKSHDYIFWCGDFNYRI.....DM.....DKDELREAL...KQSph. 75 NSDVLEILRKTRFp14qmISEHDRVIWLGDLNYRI.....AL.....SYRSAKALV...EMR... 76 NSDVMEILKKTRFprvqsSADENRVIWLGDLNYRI.....AL.....SYRSAKALV...EMQ... 77 KDNFQTILSLQQFqg7qgILDHDLVFWFGDLNFRIe....SY.....DLHFVKFAI...DSD... 78 NADVHEIHKRTVFh11klIYDHERIIWLGDLNYRL.....SS.....SYEKTRDLI...SKR... 79 NADVHEIHKRTVFh11klIYDHERIIWLGDLNYRL.....SS.....SYEKTRDLI...SKR... 80 NADVHEIHKRTVFh11klIYDHERIIWLGDLNYRL.....SS.....SYEKTRDLI...SKR... 81 NADVHEIHKRTVFh11klIYDHERIIWLGDLNYRL.....SS.....SYEKTRDLI...SKR... 82 KDNFQTILSLQQFqg7hgILDHDLVFWFGDLNFRIe....SY.....DLHFVKFAI...DSN... 83 KDNFQTILSLQQFqg7hgILDHDLVFWFGDLNFRIe....SY.....DLHFVKFAI...DSN... 84 NADVQEIHRRTHFag8rnIYDHERIFWLGDLNYRI.....DV.....AYERAHELI...STM... 85 NADFDHVYRTMTFs37peLSEADMVIFLGDFNYRLd....DI.....TYDETRDFI...SQR... 86 LEHFDRILEMQNCeg7pnILDHDLIIWFGDMNFRIe....DF.....GLHFVRESI...KNR... 87 LEHFDRILEMQNCeg7pnILDHDLIIWFGDMNFRIe....DF.....GLHFVRESI...KNR... 88 NSDVLEILRLTLFs14ekILEHDKVIWFGDLNYRI.....AL.....SYADTKNFL...MEN... 89 NQDYNAIVEGIRFddgrtISDHDHIFWVGDLNYRIqe...PP.....GQQRPGPLS...DAQ... 90 RNDYNNIYRNITFprsktIPHHDSLFWLGDLNYRI.....TL.....TNDEVRRELraqKDG... 91 RNDYNNIYRNITFprsktIPHHDSLFWLGDLNYRI.....TL.....TNDEVRRELraqKDG... 92 NADVAEILKHTQFp14erIIDHDRVLWLGDLNYRV.....AL.....TYEETRVLL...EDN... 93 HNDYKTIAKSIRFskglrIKDHDAIIWMGDFNYRI.....LM.....SNEDVRRKI...VSK... 94 NADFNHIFRLMVFs37sdLAAADMVAFFGDFNYRLf....GI.....TYDEARDFI...SQR... 95 NSDVNEILARSSFp11kkILDHDRVIFLGDLNYRI.....SL.....PEEKTRLLV...ESK... 96 NDDHDDIIRRMSFdn8rsIDEHHHIFWIGDLNYRLd....GP.....EVSQEYVNR...KDR... 97 NEDFATTLKKIRFplgreIDSHDVIFWLGDFNYRI.....NL.....SGDEVKNAV...RNG... 98 IEDYHQIVDNHKYna7rrIFDHDFVFWFGDLNFRLsg...DM.....SAWDVRTDV...ENQ... 99 NLDVTEIFKRTRFs11etIMDHDKVIWLGDLNYRL.....RA.....SSD-LHEQL...RNH... 100 NEDFATTLKKIRFplgreIDSHDVIFWLGDFNYRI.....NL.....SGDEVKNAV...RNG... 101 RSDYESIVRGITFtrtkmIPHHDSIFWLGDMNYRI.....NL.....PNEDVRRELlnqEEG... 102 NADFDHIYKTMSFt37qdLAEADMVVFFGDFNYRLf....GI.....SYDEARDFV...SQR... 103 NQDYKDICSRMQFc11ltISNHDVILWLGDLNYRIe....EL.....DVEKVKKLI...EEK... 104 KDNFQTILSLQQFq11dhEYGLGLVFWFGDLNFRIe....SY.....DLHFVKFAI...DSD... 105 INDYERIVQEQKFhv7etIFDHDYVFWFGDLNFRLtgea.TT.....SADEIRAMV...ARD... 106 NADFNHIYRSMVFs37shLASADLVAFFGDFNYRLf....GI.....TYDEARDFI...SHR... 107 LEHFDRILESLTFeg7pnILDHDLILWFGDMNFRIe....DF.....GLLFVQESI...TRK... 108 DHDYRTIASGLRFrrgrsIFNHDYVVWFGDFNYRI.....SL.....TYEEVVPCI...AQG... 109 DHDYRTIASGLRFrrgrsIFNHDYVVWFGDFNYRI.....SL.....TYEEVVPCI...AQG... 110 LLDYNRTIQALALp17dvTTRFDEVFWFGDFNFRL.....SG.....GRVAVEAFL...KQDpev 111 LLDYTRTVQALVLp17dvTTRFDEVFWFGDFNFRL.....SG.....GRTVVDALL...CQGlvv 112 LLDYSRTIQALALp17dvTTRFDEVFWFGDFNFRL.....SG.....GRVAVEAFL...KQKpev 113 IEDYKQILENHHYhv7reIYDHDYVFWFGDLNFRLqgs..DS.....STEVRELVR...DES... 114 NMEYTSISDNLVFpsgmkIYDHTNILWMGDFNYRI.....DS.....DNEEVRKLV...ELD... 115 NNDLATILDNASLf21slIMDHEVCVLHGDLNYRI.....NT.....LRPKALDLI...KKN... 116 NNDLATILDNASLf21slIMDHEVCVLHGDLNYRI.....NT.....LRPKALDLI...KKN... 117 NQDFRDIYNDMVFy20mcLYDHDVVFWFGDLNYRLntdmyGI.....SNDEVRRIA...SSD... 118 NLDVIEILKNTSFp14drITKHDRVIWLGDLNYRI.....AL.....SYSETKTLL...DKN... 119 HNDVAAILDASAFp21tmILDHELCVLNGDLNYRId....TM.....SRDTVVTAV...KQG... 120 IKDYKEINEGREKlc...TPKSDFIFWLGDLNFRIvekd.KY.....TPESIEKFI...KKK... 121 VSDVKKIIHALDLp13dvTQNFDSVYWCGDLNFRL.....SE.....PRDKLMQWI...ETT... 122 LEHFDRILEMQNCeg7pnILDHDLIIWFGDMNFRIe....DF.....GLHFVRESI...KNR... 123 LEHFDRILEMQNCeg7pnILDHDLIIWFGDMNFRIe....DF.....GLHFVRESI...KNR... 124 VSDVKRIINALDLp14dvTQNFDNVFWCGDLNFRL.....GE.....PREKLLEWI...QNT... 125 KYAYDTRLDYSKK.....DDPSDFLFWIGDLNVRV.....ET.....NATHAKSLV...DQN... 126 NEDYREITHKLSFpsgrnIFSHDYVFWCGDFNYRI.....DL.....TYEEVFYFV...KRQ... 127 NEDINTILKSMDFn27lhPRDHDIIIVAGDLNYRL.....RL.....PYETAVHLA...NAG... 128 IWDVGQILGRTRFk15ekIGDEDFTFWFGDLNFRL.....DGl85flPDPHDDPTS...LQA... 129 NTELRHIANSLLPrd...KRKRDLTVWLGDLNYRIq....DV.....SNHPVRSLI...QNH... 130 IQDYAKVVRTLRFp13deIFGSDVVLWIGDLNFRVtve..SN.....VDWRDPEKI...TEK... 131 IQDYAKVVRTLRFp13deIFGSDVVLWIGDLNFRVtve..SN.....VDWRDPEKI...TEK... 132 LEHFDRILEMQNCeg7pnILDHDLIIWFGDMNFRIe....DF.....GLHFVRESI...KNR... 133 -------------.....--------------RWI.....NL.....SYEKTHEFI...SMK... 134 VEQYHTNRNCSFPe....DKSVRAAFWFGDFNFRV.....EE.....DVNTVIRKI...KNG... 135 ----VNTIEARPE.....LSEADMVIFLGDFNYRLd....DI.....TYDETRDFI...SQR... 136 IDDYKRIMSEVCDse...VAKSDHFFFLGDLNFRV.....TS.....TYDPTTNYS...STT... 137 KRALDFVLAELSSke...NGCTPLLFVFGDLNFRL.....DSr68scVLRIEKKKF...DYF... 138 QEEIRKVFECICDees..LKGIDTVVLAGDMNFRV.....SG.....-------VP...RAL... 139 NQDYRDICSRMQFp11ltINKHDVILWLGDLNYRIe....EL.....DVGKVKKLV...---... 140 KRALDFVLAELSSke...NGCTPLLFVFGDLNFRL.....DSr60scVLRIEKKKF...DYF... 141 KRALDFVLAELSSke...NGCTPLLFVFGDLNFRL.....DSr68scVLRIEKKKF...DYF... 142 NQDYNAIVEGIRFddgrtISDHDHIFWVGDLNYRIqe...PP.....GQQRPGPLS...DAQ... 143 -------------.....------VIWLGDLNYRLc....MP.....DANEVKSLI...NKK... 144 HKALGYVLDRIIDq....RFEKVSYFVFGDFNFRL.....DSk46klFHYFNQEVF...RDN... 145 HKALGYVLDRIIDq....RFEKVSYFVFGDFNFRL.....DSk46klFDYFNQDVF...RDN... 146 HKALGYVLDRIIDq....RFEKVSYFVFGDFNFRL.....DSk46klFDYFNQEVF...RDN... 147 HKALGYVLDRIIDq....RFEKVSYFVFGDFNFRL.....DSk46klFDYFNQEVF...RDN... 148 -------------.....---FDEVFWFGDFNFRL.....SG.....GRTVVDALL...CQGlvv 149 RRALEHTLDRFHNd....KYSNVPYFLFGDFNFRT.....DTa43efSHYEHQNVF...VKN... 150 HKALGYVLDRIIDq....RFEKVSYFVFGDFNFRL.....DSk46klFDYFNQEVF...RDN... 151 HKALGYVLDRIIDq....RFEKVSYFVFGDFNFRL.....DSk46klFDYFNQEVF...RDN... 152 -------------.....-----------------.....--.....--HFVKFAI...DSD... 200 210 220 230 24 | | | | 1 NI.....DGLMA.FDQLKKAKE....QKLFDGWTEP.QVTFKPTYKFKPNTDEYDLS.....ATP 2 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.TINFGPTYKYDVGSAAYDTSdkc..RTP 3 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.TINFGPTYKYDVGSAAYDTSdkc..RTP 4 NW.....DSLIA.GDQLINQKNa...GQVFRGFLEG.KVTFAPTYKYDLFSDDYDTSekc..RTP 5 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.AVNFGPTYKYDVGSAAYDTSdkc..RTP 6 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.TINFGPTYKYDVGSAAYDTSdkc..RTP 7 NW.....DSLIA.GDQLINQKNa...GQIFRGFLEG.KVTFAPTYKYDLFSEDYDTSekc..RTP 8 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.AVNFGPTYKYDVGSAAYDTSdkc..RTP 9 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.AVNFGPTYKYDVGSAAYDTSdkc..RTP 10 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.AVNFGPTYKYDVGSAAYDTSdkc..RTP 11 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.TINFGPTYKYDVGSAAYDTSdkc..RTP 12 NW.....DSLIA.GDQLINQKNa...GQVFRGFLEG.KVTFAPTYKYDLFSDDYDTSekc..RTP 13 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.AVNFGPTYKYDVGSAAYDTSdkc..RTP 14 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.AVNFGPTYKYDVGSAAYDTSdkc..RTP 15 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.AVNFGPTYKYDVGSAAYDTSdkc..RTP 16 NW.....DSLIA.GDQLINQKNa...GQVFRGFLEG.KVTFAPTYKYDLFSDDYDTSekc..RTP 17 NW.....DSLIA.GDQLINQKNa...GQIFRGFLEG.KVTFAPTYKYDLFSEDYDTSekc..RTP 18 NW.....DSLIA.GDQLINQKNa...GQIFRGFLEG.KVTFAPTYKYDLFSDDYDTSekc..RTP 19 NW.....DSLIA.GDQLINQKNa...GQIFRGFLEG.KVTFAPTYKYDLFSEDYDTSekc..RTP 20 NW.....DSLIA.GDQLINQKNa...GQIFRGFLEG.KVTFAPTYKYDLFSEDYDTSekc..RTP 21 NW.....DSLIA.GDQLINQKNa...GQIFRGFLEG.KVTFAPTYKYDLFSDDYDTSekc..RTP 22 DW.....KKLLE.FDQLQLQKSs...GKIFKDFHEG.AINFGPTYKYDVGSAAYDTSdkc..RTP 23 DW.....KKLLE.FDQLQLQKSs...GKIFKDFHEG.AINFGPTYKYDVGSAAYDTSdkc..RTP 24 NW.....DSLIA.GDQLINQKNa...GQIFRGFLEG.KVTFAPTYKYDLFSEDYDTSekc..RTP 25 DL.....QRLLK.FDQLNIQRTq...KKAFVDFNEG.EIKFIPTYKYDSKTDRWDSSgkc..RVP 26 DL.....QRLLK.FDQLNIQRTq...KKAFVDFNEG.EIKFIPTYKYDSKTDRWDSSgkc..RVP 27 DL.....QRLLK.FDQLNIQRTq...KKAFVDFNEG.EIKFIPTYKYDSKTDRWDSSgkc..RVP 28 DL.....QRLLK.FDQLNIQRTq...KKAFVDFNEG.EIKFIPTYKYDSKTDRWDSSgkc..RVP 29 DL.....QRLLK.FDQLNIQRTq...KKAFVDFNEG.EIKFIPTYKYDSKTDRWDSSgkc..RVP 30 DL.....QRLLK.FDQLNIQRTq...KKAFVDFNEG.EIKFIPTYKYDSKTDRWDSSgkc..RVP 31 DL.....QRLLK.FDQLNIQRTq...KKAFVDFNEG.EIKFIPTYKYDSKTDRWDSSgkc..RVP 32 AF.....QTLYA.HDQLKIQVAa...RTIFDGFTEG.EITFQPTYKYDTGSDDWDTSekc..RAP 33 AF.....QTLYA.HDQLKIQVAa...RTIFDGFTEG.EITFQPTYKYDTGSDDWDTSekc..RAP 34 DF.....QMLYA.YDQLKIQVAa...KTVFEGFTEG.ELTFQPTYKYDTGSDDWDTSekc..RAP 35 AF.....QTLYA.HDQLKIQVAa...RTIFDGFTEG.EITFQPTYKYDTGSDDWDTSekc..RAP 36 AF.....QTLYA.HDQLKIQVAa...RTIFDGFTEG.EITFQPTYKYDTGSDDWDTSekc..RAP 37 NW.....ETLQQ.ADQLVQQRNl...SAVFRGFHEG.RTNFPPTYKYDIFSDDYDTSekc..RIP 38 RW.....DELKN.SDQLIRELRr...GHVFDGWREG.PIKFPPTYKYEFDSDRYAGEnl8kkRAP 39 RW.....DELKN.SDQLIRELRr...GHVFDGWREG.PIKFPPTYKYEFDSDRYAGEnl8kkRAP 40 RW.....DELKN.SDQLIRELRr...GHVFDGWREG.PIKFPPTYKYEFDSDRYAGEnl8kkRAP 41 RW.....DELKN.SDQLIRELRr...GHVFDGWREG.PIKFPPTYKYEFDSDRYAGEnl8kkRAP 42 RW.....DELKN.SDQLIRELRr...GHVFDGWREG.PIKFPPTYKYEFDSDRYAGEnl8kkRAP 43 EW.....QRLVE.YDQLSREMTk...GNLFEGWSEG.TLDFAPTYKYEIDSENYIGDdp6gkRRP 44 EW.....QRLVK.YDQLSREMTk...GNLFEGWSEG.TLDFAPTYKYEIDSENYIGDdp6gkRRP 45 EW.....QRLVE.YDQLSREMTk...GNLFEGWSEG.TLDFAPTYKYEIDSENYIGDdp6gkRRP 46 EW.....QRLVE.YDQLSREMTk...GNLFEGWSEG.TLDFAPTYKYEIDSENYIGDdp6gkRRP 47 QY.....SDLLA.HDQLLLERKd...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 48 QY.....SDLLA.HDQLLLERKd...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 49 QY.....SDLLA.HDQLLLERKd...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 50 QY.....SDLLA.HDQLLLERKd...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 51 QY.....SDLLA.HDQLLLERKd...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 52 QY.....SDLLA.HDQLLLERKd...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 53 QY.....SDLLA.HDQLLLERKd...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 54 AF.....QTLYA.HDQLKIQVAa...RTIFDGFTEG.EITFQPTYKYDTGSDDWDTSesa..RAP 55 QY.....SDLLA.HDQLLLERKe...QEVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 56 QY.....ADLLS.HDQLLTERRe...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 57 QY.....ADLLS.HDQLLTERRe...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 58 QY.....ADLLS.HDQLLTERRe...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 59 QY.....ADLLS.HDQLLTERRe...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 60 QY.....ADLLS.HDQLLTERRe...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 61 QY.....ADLLS.HDQLLTERRe...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 62 QY.....ADLLS.HDQLLTERRe...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 63 NW.....RALLE.NDQLRIEQKr...GHVFKGWNEG.KIYFPPTYKYSRNSDRYSGDdl8krRTP 64 QY.....SDLLA.HDQLLLERKd...QKVFLHFEEE.EITFAPTYRFERLTRDKYAYt10kyNLP 65 NW.....RALLE.NDQLRIEQKr...GHVFKGWNEG.KIYFPPTYKYSRNSDRYSGDdl8krRTP 66 EF.....EPLLR.VDQLNLEREk...HKVFLRFSEE.EISFPPTYRYERGSRDTYAWh10rtNVP 67 EF.....EPLLR.VDQLNLEREk...HKVFLRFSEE.EISFPPTYRYERGSRDTYAWh10rtNVP 68 EF.....EPLLR.VDQLNLEREk...HKVFLRFSEE.EISFPPTYRYERGSRDTYAWh10rtNVP 69 EF.....EPLLR.VDQLNLEREk...HKVFLRFSEE.EISFPPTYRYERGSRDTYAWh10rtNVP 70 DL.....STVLE.FDQLRKEQEa...GNVFGEFLEG.EITFDPTYKYDLFSDDYDTSekq..RAP 71 EF.....EPLLR.VDQLNLEREk...HKVFLRFSEE.EISFPPTYRYERGSRDTYAWh10rtNVP 72 DL.....STVLE.FDQLRKEQEa...GNVFGEFLEG.EITFDPTYKYDLFSDDYDTSekq..RAP 73 EF.....EPLLR.VDQLNLEREk...HKVFLRFSEE.EISFPPTYRYERGSRDTYAWh10rtNVP 74 DL.....TAVLQ.YDQLRIQQNa...GSVFNEFLEG.EISFPPTYKYDLFSDDYDTSekc..RAP 75 DW.....RALLE.KDQLRIEQRk...GCVFEGWKEG.TIYFPPTYKYSNNSDIYAGDdr8krRTP 76 NW.....RALLE.NDQLRIEQKr...GHVFKGWNEG.KIYFPPTYKYSNNSDRYAGGdl8krRTP 77 QL.....HQLWE.KDQLNMAKNt...WPILKGFQEG.PLNFAPTFKFDVGTNKYDTSakk..RKP 78 EW.....SKLLE.YDQLVKEYRk...GRAFDGWSEG.TLHFPPTYKYQANSDEYTANdg6pkRTP 79 EW.....SKLLE.YDQLVKEYRk...GRAFDGWSEG.TLHFPPTYKYQANSDEYTANdg6pkRTP 80 EW.....SKLLE.YDQLVKEYRk...GRAFDGWSEG.TLHFPPTYKYQANSDEYTANdg6pkRTP 81 EW.....SKLLE.YDQLVKEYRk...GRAFDGWSEG.TLHFPPTYKYQANSDEYTANdg6pkRTP 82 QL.....HQLWE.KDQLNMAKNt...WPILKGFQEG.PLNFAPTFKFDVGTNKYDTSakk..RKP 83 QL.....HQLWE.KDQLNMAKNt...WPILKGFQEG.PLNFAPTFKFDVGTNKYDTSakk..RKP 84 DW.....TQLAE.KDQLKRELRk...GRAFDGWTEG.VLEFAPTYKYELNSAKYIGDdq6grRTP 85 CF.....DWLRE.KDQLHTEMEa...GNVFQGMREA.IIRFPPTYKFERHQAGLAGYds6kkRIP 86 CY.....GGLWE.KDQLSIAKKh...DPLLREFQEG.RLLFPPTYKFDRNSNDYDTSekk..RKP 87 CY.....GGLWE.KDQLSIAKKh...DPLLREFQEG.RLLFPPTYKFDRNSNDYDTSekk..RKP 88 NW.....DVLFE.RDQLKIERDa...GRVFKGWNEG.KIFFAPTYKYSYNSDAYASEta8krRTP 89 TY.....ELLLQ.YDQLRQEMRr...GKCFEGYTEG.EIKFRPTYKYDPGTDNYDSSekq..RAP 90 YI.....DRLLQ.YDQLTQEINe...GVVFQGFKEP.TLQFRPTYKYDYGTDNYDTSeka..RTP 91 YI.....DRLLQ.YDQLTQEINe...GVVFQGFKEP.TLQFRPTYKYDYGTDNYDTSeka..RTP 92 DW.....DTLLE.RDQLNMERGa...GRVFSGFQEG.QIFFAPTYKYSQNSDAYAGEmt8krRTP 93 EY.....ASLFE.KDQLNQQMIa...GESFPYFHEM.AIDFPPTYKFDPGTKNYDTSekm..RIP 94 SF.....DWLRE.RDQLRAEMKv...GKVFQGMREA.LITFPPTYKFERNRSGLGGYds6kkRIP 95 KW.....NILLE.NDQLRMEIMn...GQIFRGWQEG.IVKFAPTYKYVPNSDLYYGCit9kkRAP 96 DY.....NQLYQ.HDQLYVEKRr...NRIFRDYKEG.KILFPPTYKYNPGTDEWDSSeks..RTP 97 DY.....AKLVE.NDQLTQQKAl...GQTFVGFNEG.QLTFAPTYKYDTFSDDYDTSekc..RAP 98 RY.....ADLLK.LDQLNLLREk...GNAFSLLEEQ.QPNFAPTFKFVEGTNDYNLK.....RRP 99 DW.....ESLLE.KDQLKIEQRa...GRIFKGWEEG.KIYFAPTYKYRINSDNYVVQte8krRTP 100 DY.....AKLVE.NDQLTQQKAl...GQTFVGFNEG.QLTFAPTYKYDTFSDDYDTSekc..RAP 101 YI.....DKLLH.FDQLTLGINs...GSVFEGFKEP.TLKFRPTYKYDPGTGTYDSSeke..RTP 102 SF.....DWLRE.KDQLRAEMKa...GRVFQGMREA.IITFPPTYKFERHRPGLGGYds6kkRIP 103 DF.....QMLYA.YDQLKIQVAa...KTVFEGFTEG.ELTFQPTYKYDTRALTTGIPvrsavLLP 104 QL.....HQLWE.KDQLNMAKNt...WPILKGFQEG.PLNFAPTFKFDVGTNKYDTSakk..RKP 105 EL.....KQLIE.KDQLLLVRRe...GRAFAQLQER.LPQFPPTFKFEHGSNEYDMK.....RRP 106 SF.....DWLRE.KDQLRQEMNe...GKVFQGMREA.LITFPPTYKFEKNKPGLGGYds6kkRIP 107 YY.....KELWE.KDQLFIAKKn...DQLLREFQEG.PLLFPPTYKFDRHSNNYDTSekk..RKP 108 KL.....SYLFE.YDQLNKQMLt...GKVFPFFSEL.PITFPPTYKFDIGTDIYDTSdkh..RVP 109 KL.....SYLFE.YDQLNKQMLt...GKVFPFFSEL.PITFPPTYKFDIGTDIYDTSdkh..RVP 110 DV.....LALLQ.HDQLTREMKk...GSIFKGFEEA.EIHFLPSYKFDIGKDTYDSTskq..RTP 111 DV.....PALLQ.HDQLIREMRk...GSIFKGFQEP.DIHFLPSYKFDIGKDTYDSTskq..RTP 112 DV.....LALLQ.HDQLTREMKk...GSIFRGFEEA.EIHFLPSYKFDIGKDTYDSTskq..RTP 113 QH.....EALIQ.RDQLYQVREks..QLAFQVLQER.LPAFPPTFKFREGTSEYDLK.....RRP 114 DL.....DKLAS.YDQLCTEMKk...GTVFHGLVEP.QLTFLPTYKFDNGTNDYDTSdkq..RVP 115 DI.....KTLLQ.SDQLLVERKrna.GFRLRTFTEP.EITFAPTYKYDVHSEQYDSSekk..RVP 116 DI.....KTLLQ.SDQLLVERKrna.GFRLRTFTEP.EITFAPTYKYDVHSEQYDSSekk..RVP 117 KF.....ADLLQ.HCQLREQMAr...GTVFKDFEEPsTLPFRPTYKYDCGTNTWDTSekg..RVP 118 AW.....DTLLN.KDQLKIERDa...GRVFKGWHEG.KIFFAPTYKYSYNSDAYAGDts9krRTP 119 NL.....TKLLE.RDQLLVAKRrnp.GFRLRAFDEL.PITFAPTYKYDVGTDNYDTSekk..RSP 120 DY.....DELLA.NEQLKEAKDa...GKIFKDYQEG.KIKFAPTFKLNVDEGTYNLK.....RRP 121 QFpl7lpHGFMH.TDQLTSVLSd...GAAFRGFREA.KITFPPTYKYDPGTQRFDSSskq..RAP 122 CY.....GGLWE.KDQLSIAKKh...DPLLREFQEG.RLLFPPTYKFDRNSNDYDTSekk..RKP 123 CY.....GGLWE.KDQLSIAKKh...DPLLREFQEG.RLLFPPTYKFDRNSNDYDTSekk..RKP 124 KFpl7lpHGYMH.TDQLTSVLAd...GAAFRGFMEA.NITFPPTYKYDPGSQNFDTSskq..RAP 125 NI.....DGLMA.FDQLKKAKE....QKLFDGWTEP.QVTFKPTYKFKPNTDEYDLS.....ATP 126 DW.....KKLME.FDQLQLQKSs...GKIFKDFHEG.AVNFGPTYKYDVGSAAYDTSdkc..RTP 127 QF.....SELLQ.YDELATEMKsp..HTPWLNFINF.TPTHMPTYRFDIGTDAYDTSekr..RVP 128 TL.....DSLLP.HDQLTRLIKqk..KVFHDGWHEG.TISFLPSYKYDVGTVGLFDSsekr.RAP 129 LQ.....SVLVS.KDQLLQEAEr...GEIFKGYSEG.TLGFKPTYKYNVGSSDYDTShki..RVP 130 TF.....RDVFE.TEELASHRKk...QLAFTDFKEA.PIKFPPTHKFEPDTDNYVPK.....RIP 131 TF.....RDVFE.TEELASHRKk...QLAFTDFKEA.PIKFPPTHKFEPDTDNYVPK.....RIP 132 CY.....GGLWE.KDQLSIAKKh...DPLLREFQEG.RLLFPPTYKFDRNSNDYDTSekk..RKP 133 DW.....NGLFQ.NDQLKREFKk...GHLFDGWTEG.VISFPPTYKYKVNSEKYTSDep6grRTP 134 TH.....LELLDtREQLKRALVe...RDAFIGFHEQ.PVTFEPTYRVTVGTTEQDGK.....RVP 135 CF.....DWLRE.KDQLHTEMEa...GNVFQGMREA.IIRFPPTYKFERHQAGLAGYds6kkRIP 136 TL.....RRLLE.NHEELNLLRkgedEPLCKGFQEL.KITFPPTYKFKLFEKETYNTk....RIP 137 NH.....KKLLD.DWRSYRDDDke..TENFQSMFEM.HINFPPTYPWSEDPENSETLmkt..RAP 138 DY.....SRARP.GDQCNEFRR....--AYPTFLEE.VIRFGPTYKYITGTDELCRK.....RHP 139 --.....-----.---------....----------.--------------------.....--- 140 NH.....KKLLD.DWRSYRDDDke..TENFQSMFEM.HINFPPTYPWSEDPENSETLmkt..RAP 141 NH.....KKLLD.DWRSYRDDDke..TENFQSMFEM.HINFPPTYPWSEDPENSETLmkt..RAP 142 TY.....ELLLQ.YDQLRQEMRr...GKCFEGYTEG.EIKFRPTYKYDPGTDNYDSSekq..RAP 143 DL.....QRLLK.FDQLNIQRTq...KKAFVDFNEG.EIKFIPTYKYDSKTDRWDSSgkc..RVP 144 NG.....TALLE.FDKELSVFK....DRLY----EL.DISFPPSYPYSEDSGQGRQYmnt..RCP 145 NG.....TALLE.FDKELSVFK....DRLY----EL.DISFPPSYPYSEDSSQGEQYmnt..RCP 146 NG.....TALLE.FDKELSVFK....DRLY----EL.DISFPPSYPYSEDARQGEQYmnt..RCP 147 NG.....TALLE.FDKELSVFK....DRLY----EL.DISFPPSYPYSEDARQGEQYmnt..RCP 148 DV.....PALLQ.HDQLIREMRk...GSIFKGFQEP.DIHFLPSYKFDIGKDTYDSTskq..RTP 149 SG.....QWLRE.YDRELEDFD....GRLF----EF.PIKFVPSYPFEEDINEGSNYmqt..RVP 150 NG.....TALLE.FDKELSVFK....DRLY----EL.DISFPPSYPYSEDARQGEQYmnt..RCP 151 NG.....TALLE.FDKELSVFK....DRLY----EL.DISFPPSYPYSEDARQGEQYmnt..RCP 152 QL.....HQLWE.KDQLNMAKNt...WPILKGFQEG.PLNFAPTFKFDVGTNKYDTSakk..RKP 0 250 260 270 280 | | | | | 1 SW.....TDR..ALYK.....SGTGKTIQ....PLSYNSLTNY.....KQTEHRPVLAKFRVTL 2 AW.....TDR..VLWWr25anIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 3 AW.....TDR..VLWWr25anIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 4 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 5 AW.....TDR..VLWWr25pqIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 6 AW.....TDR..VLWWr25anIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 7 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 8 AW.....TDR..VLWWr25pqIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 9 AW.....TDR..VLWWr25pqIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 10 AW.....TDR..VLWWr25pqIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 11 AW.....TDR..VLWWr25anIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 12 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 13 AW.....TDR..VLWWr25pqIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 14 AW.....TDR..VLWWr25pqIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 15 AW.....TDR..VLWWr25pqIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 16 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 17 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 18 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 19 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 20 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 21 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 22 AW.....TDR..VLWWr25tkVRHTWSPG....ALQYYGRAEL.....QASDHRPVLAIVEVEV 23 AW.....TDR..VLWWr25tkVRHTWSPG....ALQYYGRAEL.....QASDHRPVLAIVEVEV 24 AW.....TDR..VLWRr25skILYTWTPG....TLLHYGRAEL.....KTSDHRPVVALIDIDI 25 AW.....CDR..ILWR.....GTN---VN....QLNYRSHMEL.....KTSDHKPVSALFHIGV 26 AW.....CDR..ILWR.....GTN---VN....QLNYRSHMEL.....KTSDHKPVSALFHIGV 27 AW.....CDR..ILWR.....GTN---VN....QLNYRSHMEL.....KTSDHKPVSALFHIGV 28 AW.....CDR..ILWR.....GTN---VN....QLNYRSHMEL.....KTSDHKPVSALFHIGV 29 AW.....CDR..ILWR.....GTN---VN....QLNYRSHMEL.....KTSDHKPVSALFHIGV 30 AW.....CDR..ILWR.....GTN---VN....QLNYRSHMEL.....KTSDHKPVSALFHIGV 31 AW.....CDR..ILWR.....GTN---VN....QLNYRSHMEL.....KTSDHKPVSALFHIGV 32 AW.....CDR..ILWK.....GKN---IT....QLSYQSHMAL.....KTSDHKPVSSVFDIGV 33 AW.....CDR..ILWK.....GKN---IT....QLSYQSHMAL.....KTSDHKPVSSVFDIGV 34 AW.....CDR..ILWK.....GKN---IT....QLSYQSHMAL.....KTSDHKPVSSVFDIGV 35 AW.....CDR..ILWK.....GKN---IT....QLSYQSHMAL.....KTSDHKPVSSVFDIGV 36 AW.....CDR..ILWK.....GKN---IT....QLSYQSHMAL.....KTSDHKPVSSVFDIGV 37 AW.....TDR..VLWYr25prLPHLWNPG....TLIHYSRAEL.....KTSDHRPVIALIDVDL 38 AW.....CDR..ILWL.....GKG----I....RQECYKRSEI.....RMSDHRPVTSIFNVGV 39 AW.....CDR..ILWL.....GKG----I....RQECYKRSEI.....RMSDHRPVTSIFNVGV 40 AW.....CDR..ILWL.....GKG----I....RQECYKRSEI.....RMSDHRPVTSIFNVGV 41 AW.....CDR..ILWL.....GKG----I....RQECYKRSEI.....RMSDHRPVTSIFNVGV 42 AW.....CDR..ILWL.....GKG----I....RQECYKRSEI.....RMSDHRPVTSIFNVGV 43 AW.....CDR..IIWN.....GKG----M....KLFNYRRNEI.....KLSDHRPVTATFLAEV 44 AW.....CDR..IIWN.....GKG----M....KLFNYRRNEI.....KLSDHRPVTATFLAEV 45 AW.....CDR..IIWN.....GKG----M....KLFNYRRNEI.....KLSDHRPVTATFLAEV 46 AW.....CDR..IIWN.....GKG----M....KLFNYRRNEI.....KLSDHRPVTATFLAEV 47 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 48 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 49 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 50 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 51 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 52 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 53 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 54 AW.....CDR..ILWK.....GKN---IT....QLSYQSHMAL.....KTSDHKPVSSVFDIGV 55 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 56 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 57 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 58 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 59 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 60 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 61 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 62 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 63 AW.....CDR..ILWF.....GEG----L....HQLSYVRGES.....RFSDHRPVYGIFCAEV 64 SW.....CDR..VLWK.....SYPLVHVV....CQSYGSTSDI.....MTSDHSPVFATFEAGV 65 AW.....CDR..ILWF.....GEG----L....HQLSYVRGES.....RFSDHRPVYGIFCAEV 66 SW.....CDR..ILWK.....SYPETHII....CNSYGCTDDI.....VTSDHSPVFGTFEVGV 67 SW.....CDR..ILWK.....SYPETHII....CNSYGCTDDI.....VTSDHSPVFGTFEVGV 68 SW.....CDR..ILWK.....SYPETHII....CNSYGCTDDI.....VTSDHSPVFGTFEVGV 69 SW.....CDR..ILWK.....SYPETHII....CNSYGCTDDI.....VTSDHSPVFGTFEVGV 70 AW.....TDR..VLWRr10dfAASAWNPG....KLIHYGRSEL.....KQSDHRPVIAIIDAEI 71 SW.....CDR..ILWK.....SYPETHII....CNSYGCTDDI.....VTSDHSPVFGTFEVGV 72 AW.....TDR..VLWRr10dfAASAWNPG....KLIHYGRSEL.....KQSDHRPVIAIIDAEI 73 SW.....CDR..ILWK.....SYPETHII....CNSYGCTDDI.....VTSDHSPVFGTFEVGV 74 AW.....TDR..VLWRrr9adRHPGWNPG....RLVHYGRAEL.....KQSDHRPVIAMIDIEV 75 AW.....CDR..ILWH.....GSG----I....SQLSYVRGES.....RFSDHRPVYSLFSVEI 76 AW.....CDR..ILWH.....GEG----L....HQLSYVRGES.....RFSDHRPVYGIFSAEV 77 AW.....TDR..ILWKv13grKSHRLQVT....QHSYRSHMEY.....TVSDHKPVAAQFL--- 78 AW.....CDR..VLSY.....GKG----M....RLVHYRRTEQ.....KFSDHRPVTAIYMAEV 79 AW.....CDR..VLSY.....GKG----M....RLVHYRRTEQ.....KFSDHRPVTAIYMAEV 80 AW.....CDR..VLSY.....GKG----M....RLVHYRRTEQ.....KFSDHRPVTAIYMAEV 81 AW.....CDR..VLSY.....GKG----M....RLVHYRRTEQ.....KFSDHRPVTAIYMAEV 82 AW.....TDR..ILWKv13grESHRLQVT....QHSYRSHMEY.....TVSDHKPVAARFL--- 83 AW.....TDR..ILWKv13grESHRLQVT....QHSYRSHMEY.....TVSDHKPVAAQFI--- 84 AW.....CDR..ILSF.....GKG----V....KLMSYGRAEL.....TMSDHRPVVATYAAEV 85 AW.....CDR..ILYRd11csLDCPVVSS....ISQYDACMEV.....TDSDHKPVRCVFSVKI 86 AW.....TDR..ILWRl14ipPASHFSLS....LRGYSSHMTY.....GISDHKPVSGTFDLEL 87 AW.....TDR..ILWRl14ipPASHFSLS....LRGYSSHMTY.....GISDHKPVSGTFDLEL 88 AW.....CDR..ILWR.....GDG----I....LQLSYYRGES.....RFSDHRPVCGTFIVEV 89 AY.....CDR..VLWK.....GTR---IE....QLAYNSIMEI.....RQSDHKPVYAVFQVKV 90 SW.....TDR..IIYK.....GEN----L....HPLAYSDAPL.....KISDHKPVYAAYRANV 91 SW.....TDR..IIYK.....GEN----L....HPLAYSDAPL.....KISDHKPVYAAYRANV 92 ACv10crCDR..ILWK.....GEG----I....EQLSYIRGES.....RFSDHRPVCAIFAVEV 93 AW.....TDR..ILSR.....GEV---LE....QLEYKCCEDI.....LFSDHRPVYAIFRARV 94 AW.....CDR..VIYRd11snLQCPVVSS....VIMYEACMDV.....TESDHKPVRCKFHATI 95 AW.....CDR..IIWY.....GNG----L....KQHEYTRGET.....KISDHRPVKAIFTTEI 96 AW.....CDR..ILWK.....GQR---IE....MLRYNSVMQL.....RKSDHKPVYADFKVD- 97 AW.....TDR..ILWK.....DQRKKGKT....QLLSYDRSEL.....KTSDHRPVGAVFKV-- 98 AW.....CDR..ILHRvq6iyPGITLSAN....QLSYQSHMDY.....TLSDHKPVSATFNYKV 99 AW.....CDR..ILWK.....GDG----M....KQLWYVRGES.....KFSDHRPVQSLFSVHI 100 AW.....TDR..ILWK.....DQRKKGKT....QLLSYDRSEL.....KTSDHRPVGAVFKV-- 101 SW.....TDR..IIYK.....GEN----L....LPLSYSDAPI.....MISDHRPVYAAYRAKI 102 AW.....CDR..VIFRd11csLDCPVVAS....IMLYDACMDV.....TESDHKPVRCKFHVKI 103 GV.....---igFLWK.....GKN---IT....QLSYQSHMAL.....KTSDHKPVSSVFDIGV 104 AW.....TDR..ILWKv13grKSHRLQVT....QHSYRSHMEY.....TVSDHKPVAAQFL--- 105 AW.....TDR..ILYAvn6nyRNVRLTAE....QTSYKSHPSY.....SISDHKPVTSEFTLKV 106 AW.....CDR..VIYRd11csLKCPVVSS....TIMYEACMDV.....TESDHKPVRCKLHANI 107 AW.....TDR..ILWRl15svPTSYFLLT....LKNYVSHMAY.....SISDHKPVTGTFDLEL 108 AW.....TDR..ILYR.....GEL----V....PHSYQSV-PL.....YYSDHRPIYATYEANI 109 AW.....TDR..ILYR.....GEL----V....PHSYQSV-PL.....YYSDHRPIYATYEANI 110 SY.....TDR..VLYK.....SRHKGDIC....PMKYSSCPGI.....KTSDHRPVYGLFRVKV 111 SY.....TDR..VLYR.....SRHKGDIC....PVSYSSCPGI.....KTSDHRPVYGLFRVKV 112 SY.....TDR..VLYK.....SRHKGDIC....PMKYSSCPGI.....KTSDHRPVYGLFQVKV 113 AW.....TDR..IMYAvq7rqPGMQLSIE....QCSYKSHPLY.....TISDHKPVTSDFTIKL 114 SW.....TDR..ILAT.....KSF-----....TRNCYKSCDI.....RCSDHRPVFATFSLKI 115 AW.....CDR..ICYR.....GSP--DYI....SAENYTRYEL.....KASDHRPVSALI---- 116 AW.....CDR..ICYR.....GSP--DYI....SAENYTRYEL.....KASDHRPVSALI---- 117 AW.....TDR..ILTF.....KKYPQVGLes..IRPMVSIDTI.....TISDHKPVRAMFNLKV 118 AW.....CDR..ILWH.....GDG----I....RQLSYVRGES.....RFSDHRPVCSVFVVDV 119 AW.....CDR..LLYR.....GRG---RI....EQLDYRRHEV.....RVSDHRPVSGRFR--- 120 SW.....TDR..VLYK.....SETNKNID....VLAYHSLENH.....TRSDHFPVMAQYKIKV 121 AY.....TDR..ILYKf22kiSHPPSPVK....CIAYDSVQSI.....TSSDHKPVWALF---- 122 AW.....TDR..ILWRl14ipPASHFSLS....LRGYSSHMTY.....GISDHKPVSGTFDLEL 123 AW.....TDR..ILWRl14ipPASHFSLS....LRGYSSHMTY.....GISDHKPVSGTFDLEL 124 AY.....TDR..ILYKy19vsTPTQPHVQ....CLLYDSVPSI.....TTSDHKPVWALFR--- 125 SW.....TDR..ALYK.....SGTGKTIQ....PLSYNSLTNY.....KQTEHRPVLAKFRV-- 126 AW.....TDR..VLWWr25pqIRHTWSPG....TLKYYGRAEL.....QASDHRPVLAIVEVEV 127 SY.....TDR..ICMWsrr..KSMESRVR....LDRLSALMEV.....RSSDHKPVQALARIPI 128 SW.....CDR..ILYRt77drDDWVDRIR....QDIYTSHQRI.....TSSDHKPIISIFTL-- 129 AW.....TDR..ILFK.....IQDTDNIQat..LHSYDSIDQV.....YGSDHKPVKAD----- 130 SF.....TDR..VLFW.....VRNSEWLQ....NIQYDCMRGT.....TPSDHKAVFATFWLTV 131 SF.....TDR..VLFW.....VRNSEWLQ....NIQYDCMRGT.....TPSDHKAVFATFW--- 132 AW.....TDR..ILWRl14ipPASHFSLS....LRGYSSHMTY.....GISDHKPVSGTFDLEL 133 AW.....CDR..ILSF.....GKG----M....RLQAYRTVDI.....RLSDHRPVTAVYTSDV 134 SW.....TDR..ILYK.....GDG---IT....GLSYTNNKKA.....VASDHLPVVAMFRV-- 135 AW.....CDR..ILYRd11csLDCPVVSS....ISQYDACMEV.....TDSDHKPVRCVFSVKI 136 SW.....CDR..ILYK.....SYAVPTFAqegtYHSVPRSNAL.....LFSDHQPVNLTV---- 137 AW.....CDR..VLMN.....KNAYSLVEege.PQYRSFGMET.....CTGDHKPVMLTF---- 138 SW.....CDR..VFVS.....SSC--TCR....FNTYSSIHSV.....KISDHKPVVCIFEV-- 139 --.....---..----.....--------....----------.....---------------- 140 AW.....CDR..VLMN.....KNAYSLVEege.PQYRSFGMET.....CTGDHK---------- 141 AW.....CDR..VLMN.....KNAYSLVEege.PQYRSFGMET.....CTGDH----------- 142 AY.....CDR..VLWK.....GTR---IE....QLAYNSIMEI.....RQSDHKPVYAVFQVKV 143 AW.....CDR..ILWR.....GTN---VN....QLNYRSHMEL.....KTSDHKPVSALFHIGV 144 AW.....CDR..VLMSps8ilKSESEEKV....VTYDHIGPNV.....CMGDHKPVFLAFRI-- 145 AW.....CDR..ILMSls8vlKSESEEKV....ATYDHIGPNV.....CMGDHKPVFLAFRI-- 146 AW.....CDR..ILMSps8vlRSESEEKV....VTYDHIGPNV.....CMGDHKPVFLAFR--- 147 AW.....CDR..ILMSps8vlRSESEEKV....VTYDHIGPNV.....CMGDHKPVFLAFR--- 148 SY.....TDR..VLYR.....SRHKGDIC....PVSYSSCPGI.....KTSDHRPVYGLFRVKV 149 AW.....CDR..VLLN.....PTDKMLVQ....DISSPDAVEYgi7ttCMGDHKPVFLEFRM-- 150 AW.....CDR..ILMSps8vlRSESEEKV....VTYDHIGPNV.....CMGDHKPVFLAFR--- 151 AW.....CDR..ILMSps8vlRSESEEKV....VTYDHIGPNV.....CMGDHKPVFLAFR--- 152 AW.....TDR..ILWKv13grKSHRLQVT....QHSYRSHMEY.....TVSDHKPVAAQFL---