PFRMAT SS TARGET T0139 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0139.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0139.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0139.t2k.str.rdb (weight 1.53983) METHOD T0139.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0139.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0139 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0139.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3 METHOD METHOD ============================================ METHOD Comments from T0139.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0139 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0139.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3 METHOD METHOD ============================================ METHOD Comments from T0139.t2k.str.rdb METHOD ============================================ METHOD TARGET T0139 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0139.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3 METHOD METHOD ============================================ METHOD Comments from T0139.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0139 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0139.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3 METHOD METHOD ============================================ MODEL 1 T C 0.82 G C 0.78 I C 0.66 S C 0.67 R C 0.48 E H 0.49 T H 0.55 S H 0.69 S H 0.76 D H 0.87 V H 0.88 A H 0.87 L H 0.86 A H 0.89 S H 0.89 H H 0.89 I H 0.90 L H 0.91 T H 0.90 A H 0.86 L H 0.77 R H 0.68 E C 0.52 K C 0.75 Q C 0.82 A C 0.84 P C 0.81 E C 0.60 L C 0.54 S C 0.54 L C 0.61 S C 0.67 S C 0.50 Q C 0.52 D C 0.51 L H 0.57 E H 0.58 L H 0.55 V C 0.51 T C 0.61 K C 0.59 E C 0.65 D C 0.82 P H 0.62 K H 0.68 A H 0.72 L H 0.74 A H 0.67 V H 0.59 A H 0.56 L H 0.45 N C 0.45 W C 0.50 D C 0.53 I H 0.50 K H 0.49 K H 0.54 T H 0.63 E H 0.76 T H 0.79 V H 0.87 Q H 0.88 E H 0.89 A H 0.86 C H 0.82 E H 0.87 R H 0.88 E H 0.89 L H 0.90 A H 0.89 L H 0.87 R H 0.85 L H 0.87 Q H 0.84 Q H 0.82 T H 0.74 Q H 0.72 S H 0.66 L H 0.64 H H 0.51 S C 0.57 L C 0.72 R C 0.91 END