PFRMAT SS TARGET T0138 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0138.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0138.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0138.t2k.str.rdb (weight 1.53983) METHOD T0138.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0138.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0138 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0138.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3 METHOD METHOD ============================================ METHOD Comments from T0138.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0138 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0138.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3 METHOD METHOD ============================================ METHOD Comments from T0138.t2k.str.rdb METHOD ============================================ METHOD TARGET T0138 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0138.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3 METHOD METHOD ============================================ METHOD Comments from T0138.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0138 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0138.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3 METHOD METHOD ============================================ MODEL 1 M C 0.91 L C 0.84 S C 0.80 Q C 0.61 I E 0.47 A E 0.64 I E 0.72 C E 0.73 I E 0.68 W E 0.60 V C 0.47 E C 0.73 S C 0.70 T H 0.76 A H 0.84 I H 0.88 L H 0.90 Q H 0.90 D H 0.90 C H 0.90 Q H 0.90 R H 0.87 A H 0.81 L H 0.67 S H 0.54 A C 0.52 D C 0.61 R H 0.72 Y H 0.71 Q H 0.74 L H 0.65 Q H 0.60 V H 0.61 C H 0.58 E H 0.57 S H 0.57 G H 0.83 E H 0.90 M H 0.91 L H 0.93 L H 0.94 E H 0.93 Y H 0.92 A H 0.89 Q H 0.81 T H 0.62 H C 0.65 R C 0.50 D C 0.59 Q C 0.53 I C 0.58 D E 0.50 C E 0.87 L E 0.89 I E 0.90 L E 0.87 V E 0.75 A C 0.50 A C 0.76 N C 0.78 P C 0.73 S C 0.64 F H 0.76 R H 0.92 A H 0.94 V H 0.95 V H 0.95 Q H 0.95 Q H 0.94 L H 0.91 C H 0.85 F H 0.67 E C 0.65 G C 0.81 V C 0.64 V E 0.68 V E 0.73 P E 0.80 A E 0.89 I E 0.91 V E 0.90 V E 0.81 G E 0.52 D C 0.78 R C 0.85 D C 0.78 S C 0.79 E C 0.82 D C 0.85 P C 0.82 D C 0.83 E C 0.85 P C 0.84 A C 0.83 K C 0.79 E C 0.80 Q C 0.69 L C 0.48 Y E 0.67 H E 0.72 S E 0.75 A E 0.80 E E 0.86 L E 0.86 H E 0.84 L E 0.59 G C 0.72 I H 0.64 H H 0.71 Q H 0.79 L H 0.86 E H 0.82 Q H 0.74 L H 0.59 P H 0.80 Y H 0.90 Q H 0.92 V H 0.95 D H 0.96 A H 0.96 A H 0.95 L H 0.95 A H 0.95 E H 0.92 F H 0.91 L H 0.85 R H 0.75 L H 0.63 A C 0.62 P C 0.59 V C 0.46 E C 0.49 T C 0.57 M C 0.75 A C 0.92 END