PFRMAT SS TARGET T0137 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0137.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0137.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0137.t2k.str.rdb (weight 1.53983) METHOD T0137.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0137.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0137 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0137.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 111 METHOD METHOD ============================================ METHOD Comments from T0137.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0137 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0137.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 111 METHOD METHOD ============================================ METHOD Comments from T0137.t2k.str.rdb METHOD ============================================ METHOD TARGET T0137 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0137.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 111 METHOD METHOD ============================================ METHOD Comments from T0137.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0137 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0137.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 111 METHOD METHOD ============================================ MODEL 1 M C 0.90 E C 0.80 A C 0.74 F C 0.59 L C 0.54 G E 0.63 T E 0.79 W E 0.86 K E 0.87 M E 0.84 E E 0.71 K E 0.62 S C 0.57 E C 0.65 G C 0.66 F H 0.83 D H 0.94 K H 0.95 I H 0.95 M H 0.95 E H 0.95 R H 0.90 L C 0.60 G C 0.94 V C 0.92 D C 0.88 F H 0.90 V H 0.94 T H 0.94 R H 0.93 K H 0.93 M H 0.92 G H 0.87 N H 0.74 L H 0.47 V C 0.71 K C 0.84 P C 0.77 N E 0.59 L E 0.90 I E 0.92 V E 0.92 T E 0.87 D E 0.57 L C 0.79 G C 0.88 G C 0.88 G C 0.81 K E 0.75 Y E 0.88 K E 0.91 M E 0.92 R E 0.89 S E 0.82 E E 0.63 S C 0.53 T C 0.66 F C 0.62 K E 0.49 T E 0.62 T E 0.82 E E 0.89 C E 0.89 S E 0.88 F E 0.86 K E 0.77 L E 0.50 G C 0.74 E C 0.58 K E 0.60 F E 0.67 K E 0.73 E E 0.73 V E 0.78 T C 0.53 P C 0.79 D C 0.92 S C 0.91 R C 0.61 E E 0.82 V E 0.86 A E 0.88 S E 0.90 L E 0.92 I E 0.92 T E 0.90 V E 0.79 E C 0.65 N C 0.93 G C 0.91 V E 0.76 M E 0.92 K E 0.91 H E 0.92 E E 0.91 Q E 0.89 D E 0.69 D C 0.68 K C 0.84 T C 0.85 K C 0.70 V E 0.60 T E 0.82 Y E 0.89 I E 0.91 E E 0.92 R E 0.91 V E 0.91 V E 0.89 E E 0.59 G C 0.92 N C 0.85 E E 0.80 L E 0.92 K E 0.92 A E 0.93 T E 0.93 V E 0.92 K E 0.89 V E 0.75 D C 0.89 E C 0.86 V E 0.83 V E 0.90 C E 0.91 V E 0.91 R E 0.88 T E 0.85 Y E 0.81 S E 0.76 K E 0.64 V C 0.67 A C 0.93 END