PFRMAT SS TARGET T0136 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0136.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0136.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0136.t2k.str.rdb (weight 1.53983) METHOD T0136.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0136.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0136 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0136.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 72 METHOD METHOD ============================================ METHOD Comments from T0136.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0136 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0136.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 72 METHOD METHOD ============================================ METHOD Comments from T0136.t2k.str.rdb METHOD ============================================ METHOD TARGET T0136 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0136.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 72 METHOD METHOD ============================================ METHOD Comments from T0136.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0136 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0136.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 72 METHOD METHOD ============================================ MODEL 1 A C 0.89 E C 0.80 N H 0.56 N H 0.62 N H 0.66 L H 0.71 K H 0.70 L H 0.65 A H 0.87 S H 0.92 T H 0.92 M H 0.94 E H 0.95 G H 0.95 R H 0.95 V H 0.96 E H 0.96 Q H 0.95 L H 0.95 A H 0.96 E H 0.95 Q H 0.95 R H 0.95 Q H 0.95 V H 0.94 I H 0.92 E H 0.84 A H 0.58 G C 0.73 G C 0.79 G C 0.68 E H 0.93 R H 0.95 R H 0.95 V H 0.95 E H 0.94 K H 0.92 Q H 0.89 H H 0.88 S H 0.82 Q C 0.56 G C 0.88 K C 0.86 Q C 0.73 T C 0.83 A H 0.90 R H 0.94 E H 0.95 R H 0.95 L H 0.94 N H 0.92 N H 0.86 L H 0.76 L H 0.53 D C 0.85 P C 0.84 H C 0.89 S C 0.79 F C 0.38 D H 0.48 E H 0.55 V H 0.78 G H 0.83 A H 0.90 F H 0.87 R H 0.84 K H 0.71 H H 0.61 R C 0.50 T C 0.55 T C 0.66 L C 0.72 F C 0.72 G C 0.77 M C 0.65 D C 0.60 K C 0.54 A C 0.61 V C 0.70 V C 0.91 END