PFRMAT SS TARGET T0135 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0135.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0135.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0135.t2k.str.rdb (weight 1.53983) METHOD T0135.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0135.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0135 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0135.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 14 METHOD METHOD ============================================ METHOD Comments from T0135.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0135 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0135.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 14 METHOD METHOD ============================================ METHOD Comments from T0135.t2k.str.rdb METHOD ============================================ METHOD TARGET T0135 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0135.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 14 METHOD METHOD ============================================ METHOD Comments from T0135.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0135 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0135.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 14 METHOD METHOD ============================================ MODEL 1 M C 0.90 A C 0.81 T C 0.79 R C 0.79 T C 0.74 P C 0.71 K C 0.66 L C 0.45 V E 0.54 K E 0.71 H E 0.90 T E 0.91 L E 0.92 L E 0.91 T E 0.87 R E 0.80 F E 0.56 K C 0.72 D C 0.74 E C 0.82 I C 0.86 T C 0.89 R H 0.83 E H 0.89 Q H 0.93 I H 0.95 D H 0.95 N H 0.95 Y H 0.95 I H 0.94 N H 0.90 D H 0.86 Y H 0.87 T H 0.87 N H 0.83 L H 0.85 L H 0.81 D H 0.66 L H 0.59 I C 0.65 P C 0.65 S C 0.55 M E 0.61 K E 0.73 S E 0.78 F E 0.71 N E 0.60 W C 0.60 G C 0.74 T C 0.73 D C 0.73 L C 0.74 G C 0.77 M C 0.56 E C 0.54 S C 0.53 A H 0.63 E H 0.67 L H 0.66 N C 0.49 R C 0.73 G C 0.85 Y C 0.79 T C 0.62 H E 0.85 A E 0.92 F E 0.92 E E 0.90 S E 0.79 T E 0.64 F C 0.61 E C 0.81 S C 0.89 K H 0.81 S H 0.87 G H 0.90 L H 0.94 Q H 0.93 E H 0.90 Y H 0.89 L H 0.78 D H 0.61 S C 0.77 A H 0.78 A H 0.79 L H 0.84 A H 0.81 A H 0.74 F H 0.74 A H 0.73 E H 0.66 G H 0.60 F H 0.46 L H 0.44 P H 0.56 T H 0.53 L H 0.46 S C 0.62 Q C 0.76 R C 0.58 L E 0.75 V E 0.87 I E 0.86 D E 0.76 Y E 0.50 F C 0.50 L C 0.64 Y C 0.92 END