PFRMAT SS TARGET T0134 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0134.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0134.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0134.t2k.str.rdb (weight 1.53983) METHOD T0134.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0134.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0134 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0134.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 4 METHOD METHOD ============================================ METHOD Comments from T0134.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0134 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0134.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 4 METHOD METHOD ============================================ METHOD Comments from T0134.t2k.str.rdb METHOD ============================================ METHOD TARGET T0134 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0134.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 4 METHOD METHOD ============================================ METHOD Comments from T0134.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0134 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0134.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 4 METHOD METHOD ============================================ MODEL 1 G C 0.92 E C 0.84 P C 0.74 V C 0.68 Q C 0.68 N C 0.64 G C 0.69 A C 0.71 P C 0.63 E C 0.65 E C 0.73 E C 0.79 Q C 0.82 L C 0.86 P C 0.89 P C 0.79 E C 0.79 S C 0.75 S H 0.51 Y H 0.59 S H 0.62 L H 0.62 L H 0.55 A H 0.44 E C 0.55 N C 0.73 S C 0.71 Y E 0.48 V E 0.70 K E 0.81 M E 0.88 T E 0.85 C E 0.79 D E 0.53 I C 0.68 R C 0.79 G C 0.76 S C 0.81 L C 0.58 Q C 0.59 E C 0.62 D C 0.81 S C 0.79 Q E 0.50 V E 0.81 T E 0.89 V E 0.91 A E 0.92 I E 0.92 V E 0.92 L E 0.86 E E 0.60 N C 0.65 R C 0.74 S C 0.77 S C 0.57 S C 0.48 I H 0.41 L C 0.35 K E 0.34 G E 0.43 M E 0.45 E E 0.50 L E 0.39 S H 0.38 V H 0.57 L H 0.61 D H 0.61 S H 0.59 L H 0.58 N H 0.51 A H 0.49 R H 0.48 M H 0.37 A C 0.45 R C 0.75 P C 0.82 Q C 0.86 G C 0.87 S C 0.83 S C 0.69 V C 0.70 H C 0.74 D C 0.79 G C 0.79 V C 0.60 P C 0.54 V C 0.64 P C 0.63 F C 0.60 Q C 0.66 L C 0.81 P C 0.90 P C 0.83 G C 0.88 V C 0.81 S C 0.83 N C 0.77 E C 0.67 A C 0.55 Q E 0.59 Y E 0.80 V E 0.87 F E 0.85 T E 0.85 I E 0.78 Q E 0.68 S E 0.55 I H 0.47 V H 0.59 M H 0.70 A H 0.72 Q H 0.63 K H 0.53 L C 0.47 K C 0.60 G C 0.49 T E 0.68 L E 0.79 S E 0.83 F E 0.83 I E 0.83 A E 0.69 K C 0.50 N C 0.70 D C 0.78 E C 0.81 G C 0.84 A C 0.81 T C 0.76 H C 0.65 E C 0.52 K C 0.45 L E 0.43 D E 0.46 F E 0.59 R E 0.59 L E 0.48 H C 0.52 F C 0.54 S C 0.54 C E 0.56 S E 0.60 S E 0.76 Y E 0.84 L E 0.84 I E 0.64 T C 0.67 T C 0.82 P C 0.81 C C 0.78 Y C 0.74 S C 0.61 D H 0.60 A H 0.81 F H 0.87 A H 0.90 K H 0.89 L H 0.88 L H 0.80 E H 0.59 S C 0.66 G C 0.86 D C 0.80 L C 0.58 S C 0.62 M C 0.58 S C 0.65 S C 0.53 I E 0.66 K E 0.75 V E 0.65 D C 0.66 G C 0.64 I E 0.63 R E 0.74 M E 0.77 S E 0.72 F H 0.68 Q H 0.87 N H 0.88 L H 0.93 L H 0.93 A H 0.94 K H 0.93 I H 0.91 C H 0.87 F H 0.77 H H 0.58 H C 0.60 H C 0.73 F C 0.55 S E 0.60 V E 0.70 V E 0.72 E E 0.67 R E 0.54 V C 0.57 D C 0.66 S C 0.48 C H 0.52 A H 0.43 S C 0.40 M H 0.44 Y C 0.44 S C 0.50 R C 0.43 S C 0.50 I C 0.68 Q C 0.87 G C 0.88 H C 0.68 H E 0.69 V E 0.84 C E 0.89 L E 0.90 L E 0.90 V E 0.87 K E 0.81 K E 0.56 G C 0.73 E C 0.80 N C 0.83 S C 0.61 V E 0.71 S E 0.79 V E 0.71 D C 0.68 G C 0.82 K C 0.75 C C 0.76 S C 0.86 D C 0.79 S H 0.81 T H 0.87 L H 0.91 L H 0.94 S H 0.94 N H 0.94 L H 0.94 L H 0.95 E H 0.95 E H 0.92 M H 0.93 K H 0.94 A H 0.93 T H 0.91 L H 0.84 A H 0.68 K C 0.53 C C 0.91 END