(c) 1992-2000 Regents of the University of California, Santa Cruz
Sequence Alignment and Modeling Software System
http://www.cse.ucsc.edu/research/compbio/sam.html
Citations (SAM, SAM-T99, HMMs)
- R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
- K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
- A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.
Sequence numbers correspond to the following labels:
-
- T0129 HI0817, H. influenzae
-
- gi|15803444|ref|NP_289477.1|_8:194 (NC_002655) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
- gi|15833034|ref|NP_311807.1| (NC_002695) hypothetical protein [Escherichia coli O157:H7]
- gi|16130811|ref|NP_417385.1| (NC_000913) orf, hypothetical protein [Escherichia coli K12]
- gi|421140|pir||A47020 hypothetical 21.5K protein (pepP-ssr intergenic region) - Escherichia coli
- gi|216626|dbj|BAA14324.1| (D90281) ORF194 protein [Escherichia coli]
- gi|882439|gb|AAA69077.1| (U28377) ORF_f194 [Escherichia coli]
- gi|1789276|gb|AAC75947.1| (AE000374) orf, hypothetical protein [Escherichia coli K12]
- gi|12517439|gb|AAG58036.1|AE005521_4 (AE005521) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
- gi|13363252|dbj|BAB37203.1| (AP002563) hypothetical protein [Escherichia coli O157:H7]
-
-
- gi|16766360|ref|NP_461975.1|_8:194 (NC_003197) putative cytoplasmic protein [Salmonella typhimurium LT2]
- gi|16421610|gb|AAL21934.1| (AE008840) putative cytoplasmic protein [Salmonella typhimurium LT2]
-
- gi|16761840|ref|NP_457457.1|_8:194 (NC_003198) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
- gi|16504142|emb|CAD02889.1| (AL627277) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]
-
- gi|16121216|ref|NP_404529.1|_7:192 (NC_003143) putative exported protein [Yersinia pestis]
- gi|15978982|emb|CAC89755.1| (AJ414145) putative exported protein [Yersinia pestis]
-
-
- gi|16272758|ref|NP_438977.1|_1:182 (NC_000907) conserved hypothetical protein [Haemophilus influenzae Rd]
- gi|1176090sp|P44882|YGFB_HAEIN Hypothetical protein HI0817
- gi|1074520|pir||I64158 hypothetical protein HI0817 - Haemophilus influenzae (strain Rd KW20)
- gi|1573830|gb|AAC22476.1| (U32764) conserved hypothetical protein [Haemophilus influenzae Rd]
-
-
- gi|15600418|ref|NP_253912.1|_5:184 (NC_002516) hypothetical protein [Pseudomonas aeruginosa]
- gi|13878884sp|Q9HTW5|YGFB_PSEAE Hypothetical protein PA5225
- gi|11350394|pir||A82993 hypothetical protein PA5225 [imported] - Pseudomonas aeruginosa (strain PAO1)
- gi|9951533|gb|AAG08610.1|AE004935_7 (AE004935) hypothetical protein [Pseudomonas aeruginosa]
-
- gi|15642472|ref|NP_232105.1|_2:157 (NC_002505) conserved hypothetical protein [Vibrio cholerae]
- gi|11354711|pir||F82071 conserved hypothetical protein VC2476 [imported] - Vibrio cholerae (group O1 strain N16961)
- gi|9657055|gb|AAF95618.1| (AE004317) conserved hypothetical protein [Vibrio cholerae]
10 20 30 40 50 60
| | | | | |
1 MLISHSDLNQQLKSAGIGFNATELHGFLSGLLCGG..LKDQSWLPLLYQFSNDNHAYPTGLVQPV
2 EMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGG..NDDSSWLPLLHDLTNEGMAFGHELAQAL
3 EMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGG..NDDSSWLPLLHDLTNEGMAFGHELAQAL
4 EMPGYNEMNRFLNQQGAGLTPAEMHGLISGMICGG..NNDSSWQPLLHDLTNEGLAFGHELAQAL
5 EMPGYDEMNRFLNQQGAGLTPAEMHGLISGMICGG..NNDSSWQPLLHDLTNEGLAFGHELAQAL
6 -LPTYPSLALALSQQAVALTPAEMHGLISGMLCGG..SKDNGWQTLVHDLTNEGVAFPQALSLPL
7 --SSYSDFSQQLKTAGIALSAAELHGFLTGLICGG..IHDQSWQPLLFQFTNENHAYPTALLQEV
8 MLISHSDLNQQLKSAGIGFNATELHGFLSGLLCGG..LKDQSWLPLLYQFSNDNHAYPTGLVQPV
9 RLPAYPALANELRTASLGINPAELQGLLTGMLSGGlsLNDKSWQALVFDYTNDGMGWPIGALASA
10 -NSAYSAFSSLLAEAAMPVSPAELHGHLLGRVCAGagFDEAAWQHAAAELL--GGAPGERLKAAL
11 -------------------------------LSGGlsLNDKSWQALVFDYTNDGMGWPIGALASA
70 80 90 100 110 120
| | | | | |
1 TELYEQISQTLSDVEGFTFELGLTEDEN...VFTQADSLSDWANQFLLGIGLAQPELAKEKGEIG
2 RKMHSATSDALQD-DGFLFQLYLPDGDDvs.VFDRADALAGWVNHFLLGLGVTQPKLDKVTGETG
3 RKMHSATSDALQD-DGFLFQLYLPDGDDvs.VFDRADALAGWVNHFLLGLGVTQPKLDKVTGETG
4 RKMHAATSDALED-DGFLFQLYLPEGDDvs.VFDRADALAGWVNHFLLGLGVTQPKLDKVTGETG
5 RKMHAATSDALED-DGFLFQLYLPEGDDvs.VFDRADALAGWVNHFLLGLGVTQPKLDKVTGETG
6 QQLHEATQEALEN-EGFMFQLLIPEGEDvt.VFDRADALSGWVNHFLLGLGMLQPKLAQVKDEVG
7 TQIQQHISKKLADIDGFDFELWLPENEDd..VFTRADALSEWTNHFLLGLGLAQPKLDKEKGDIG
8 TELYEQISQTLSDVEGFTFELGLTEDEN...VFTQADSLSDWANQFLLGIGLAQPELAKEKGEIG
9 EQILLAMSAQLVDTD-FELSLLLPEGEGeeaLFELADAVAEWINHFISGLGLSGANLKHASVEAK
10 SGLLGMVRQDFSAGE-VAVVMLLPDDETp..LAQRTEALGQWCQGFLAGFGLTARE-GSLTGEAE
11 EQILLAMSAQLVDTD-FELSLLLPEGEGeeaLFELADAVAEWINHFISGLGLSGANLKHASVEAK
130 140 150 160 170 180
| | | | | |
1 EAVDDLQDICQLGYDEDDNEEELAEALEEIIEYVRTIAMLFYSHFN.EG.EIE....SKPVLH
2 EAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFT.HP.QPTapevQKPTLH
3 EAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFT.HP.QPTapevQKPTLH
4 EAIDDLRNIAQLGYDESEDQEELEMSLEEIIEYVRVAALLCHDTFT.RQ.QPTapevRKPTLH
5 EAIDDLRNIAQLGYDESEDQEELEMSLEEIIEYVRVAALLCHDTFT.RQ.QPTapevRKPTLH
6 EAIDDLRNIAQLGYDEDEDQEELAQSLEEVVEYVRVAAILCHIEFT.QQ.KPTapemHKPTLH
7 EAIDDLHDICQLGYDESDDKEELSEALEEIIEYVRTLACLLFTHFQ.PQ.LPE....QKPVLH
8 EAVDDLQDICQLGYDEDDNEEELAEALEEIIEYVRTIAMLFYSHFN.EG.EIE....SKPVLH
9 EALEDLEEMSKLGIDEEDDLAEQAELLEQVIEHIKACVLVLHAEFGvKP.EQD....TKPTVH
10 EVLQDMAAIAQVQGQLEDSEDGETDYME-VMEYLRVAPLLLFAECG.KPlEPA....PKPSLH
11 EALEDLEEMSKLGIDEEDDLAEQAELLEQVIEHIKACVLVLHAEFGvKP.EQD....TKPTVH