CASP4 Target T0097

1. Protein Name

C-domain of ERp29

2. Organism Name

rat

3. Number of amino acids (approx)

105

4. Accession number

U36482

5. Sequence Database

Genbank

6. Amino acid sequence

GCLPAYDALA
GQFIEASSRE
ARQAILKQGQ
DGLSGVKETD
KKWASQYLKI
MGKILDQGED
FPASELARIS
KLIENKMSEG
KKEELQRSLN
ILTAFRKKGA
EKEEL

7. Additional Information

monomer, no disulfides, pH 5. The full length protein contains
an N-terminal domain with similarity to a PDI domain. Sequence
alignment with the C-domain (submitted here) yields no protein
of known structure. The C-domain forms a monomeric
globular structure on its own, independent of the N-domain.

References with the sequence of ERp29 and proteins related
to the C-domain of ERp29 (by sequence alignment):
Mkrtchian S. Fang C. Hellman U. Ingelman-Sundberg M.
A stress-inducible rat liver endoplasmic reticulum protein, ERp29.
European Journal of Biochemistry. 251(1-2):304-13, 1998
Ferrari, D.M., Van, P.N., Kratzin, H.D., Söling, H.D. (1998) Eur. J. Biochem. 255, 570-579
Ferrari DM, Soling HD. Biochem J. 1999, 339 ( Pt 1):1-10.
Konsolaki, M. and Shüpbach, T. (1998) Genes & Development 12, 120-131

8. Homologous Sequence of known structure

no

9. Current state of the experimental work

NMR structure completed. Coordinates will be provided 1st
September 2000.

10. Interpretable map?

yes

11. Estimated date of chain tracing completion

finished structure

12. Estimated date of public release of structure

1st Sept. 2000

13. Name

Unavailable until after public release of structure