(c) 1992-2000 Regents of the University of California, Santa Cruz
Sequence Alignment and Modeling Software System
http://www.cse.ucsc.edu/research/compbio/sam.html

Citations (SAM, SAM-T99, HMMs)

Sequence numbers correspond to the following labels:

    • T0087-1-180 
              10        20                  30           40            
              |         |                   |            |            
   1 MSKILVFGHQNPDSDAIGSSMAYAYLK.....R.....QLGV.DAQ..AVALGNP.....NEET.
   2 MSKILVFGHQNPDSDAIGSSMAYAYLK.....R.....QLGV.DAQ..AVALGNP.....NEET.
   3 MSKILVFGHQNPDSDAIGSSYAFAYLA.....Re....AYGL.DTE..AVALGEP.....NEET.
   4 MEKILIFGHQNPDTDTICSAIAYADLK.....N.....KLGF.NAE..PVRLGQV.....NGET.
   5 -ERVYVIGHKNPDTDSVCSAIGYAHFK.....Nnv...EKGK.TFI..PARSGDL.....TNES.
   6 -ERVYVIGHKNPDTDSVCSAIGYAHFK.....Nnv...EKGK.TFI..PARSGDL.....TNES.
   7 FDKFSLFVHVNPDFDAFGSAFAFKTFL.....N.....TFFS.EKK..AYVMGSY.....N-IN.
   8 -DTLLIVMHDNPDPDCMASASALAVIA.....Q.....SIGL.KTQ..IVYGGDIt....HHQN.
   9 ---VYVVGHKNPDTDSVCSAIAFAYLW.....Nk12mmKIEA.EAK..PVIQGDV.....NPET.
  10 ----AVFGHLNPDTDAISAAMVYARLL.....T.....RQGT.EAQ..AYRLGEP.....NFET.
  11 -DSLLIVMHDNPDPDSMASASALAVIA.....Q.....SVGL.RPQ..IVYGGDIt....HHQN.
  12 -KRLGIFTHDNPDPDSMSSAYALREIA.....K.....QFDV.IAD..ILYYGEIl....HQKN.
  13 ----YVVGHKNPDTDSIASAIVLAYFL.....-.....----.DCY..PARLGDI.....NPET.
  14 FDKIVIFHHVRPDGDCLGAQQGLFHLI.....K.....ANFK.NKE..VKCVGNN.....NNLF.
  15 HDKIVIFHHIRPDGDCLGAQHGLARLI.....Q.....TNFP.HKQ..VFCVGDP.....KHNF.
  16 -EGIILLCHHNADPDSLGSAIAFSNFL.....L.....SKGFsRIR..IGVAQSI.....ASYS.
  17 ---ILVVGHKNPDSDSICSALVAAELL.....K.....ARGL.EAK..AVRQGEI.....NRET.
  18 FDNFSLYVHVNPDFDAFGAAFAFKAFL.....A.....VYFP.HKK..AYVMGSH.....N-IK.
  19 HDRILVVGHIMPDGDCVSSVLSLTLGL.....E.....KLGK.EVK..AAVDYKI.....PYVF.
  20 YDTIILHRHVRPDPDAYGSQCGLTEIL.....R.....ETYP.EKN..IFAVGTP.....EPSL.
  21 RDEVLFLCHHNADPDAVGSCVALKYLA.....S.....QLNP.NGK..FR--ISA.....DSVS.
  22 YNNFVIIGHKDPDFDCIGSSLALSSFL.....S.....RIGK.NSI..LLNEGPFi....RKEI.
  23 KGSILILTHENPDGDSLGSGLALYKFL.....K.....KKGK.EVY..IGSKDGV.....PHFL.
  24 -EGIILLCHHNADPDSLGSAIAFSNFL.....L.....DRGLrNVR..IGVAQSI.....ASYS.
  25 FNKITIFVHTNPDCDALGSAFALARIL.....K.....LNTF.GTR..VKIVGVN.....ALNP.
  26 ----VITTHRSPDFDAFASCVAAKKLL.....D.....----.DHI..IVLPSNP.....ARNL.
  27 --RVGVVCHVHPDADTIGAGLALALVL.....D.....GCGK.RVE..VSFAAPAtl...PESL.
  28 ----LILCHQTADFDVLGAAVGLAKLH.....-.....---P.GSR..IVLTGGS.....HPTV.
  29 -EKSAVITHRNADPDAVGAALVVREVL.....R.....ALRM.NPC..LYSPEGI.....SRQS.
  30 -SNVIIMGHKFPDMDSIGAAIGILKVA.....Q.....ANNK.DGF..IVIDPNQig8rlIGEI.
  31 ----VVILSEGADLDSLSAAYGVLKLY.....P.....D---.---..-AYLLKP.....KHLS.
  32 --PLLILTHINPDPDAIASAMALKTLA.....E.....RWGV.DSD..IAYGGNIg....YDEN.
  33 ----FVSGNESADLDSCASSIVYAYCL.....Q.....RKQL.GRI..VVPFFNIpr7rlRPEL.
  34 PGPIVVLSHENPDGDALGSVLGLSRAL.....R.....TLGK.TV-..-LAPMTV.....PHYL.
  35 -QRLILVIQDFPDPDALSSAWAFQLIA.....A.....QYEI.QCD..IVYAGTLs....HQEN.
  36 HRAFAVVGHEKPDGDCVGSSLALASFL.....R.....RIGK.EVE..LLSAGPF.....KR--.
  37 ----ICVGNESADMDSIASAITYSYCQyi9ysE.....EKKK.GSF..IVPIIDI.....PREDl
  38 ----ICVGNESADMDSIASAITYSYCQyi9ysE.....EKKK.GSF..IVPIIDI.....PREDl
  39 ----VVQGNEGGDMDSIVGCIYLAMLF.....D.....KQPK.FGFenPVPALNF.....PQED.
  40 HGSFLLLGHEHPDEDCIASLVAFALLL.....T.....RCNK.RVE..ICCQGPI.....RVQI.
  41 -------GNEACDLDSTVSALALAFYLa....K.....TTEA.EEV..FVPVLNI.....KRSE.
  42 ---------------------------.....-.....----.---..-------.....----.


            50          60                  70             80          
            |           |                   |              |          
   1 ....AFVLD..YFGIQAPPV....VK.SAQA.....EGAKQVI.....LTDHNEFQQS.....IA
   2 ....AFVLD..YFGIQAPPV....VK.SAQA.....EGAKQVI.....LTDHNEFQQS.....IA
   3 ....AFVLD..YFGVAAPRV....IT.SAKA.....EGAEQVI.....LTDHNEFQQS.....VA
   4 ....QYALD..YFKQESPRL....VE.-TAA.....NEVNGVI.....LVDHNERQQS.....IK
   5 ....LFVLK..YFGMNPPLH....IE.TLEPt231kDVRKKVI.....LVDHNEITQA.....PE
   6 ....LFVLK..YFGMNPPLH....IE.TLEPt231kDVRKKVI.....LVDHNEITQA.....PE
   7 ....ADGRE..LFPFEQTDI....ND.DFVK.....ES--LAI.....IFDTSNQERV.....LT
   8 ....RAMVN..VLGMEFRKV....SRgSYEI.....KRHKAIA.....IVDAQPNGNIti...LD
   9 ....KYVLE..KFGFEVPEI....MT.N---.....GEGKKVA.....LVDHSEKAQT.....VD
  10 ....AYVLR..ELGLEAPPL....LT.ELPA.....GS--KVA.....LVDHNESAQS.....LP
  11 ....RAMVN..VLGMEFKKV....LRgSYEI.....KRYDAIA.....IVDAQPNGNIti...LD
  12 ....RAMVN..LLEIPMIRA....P-.EVDL.....SHYDAFA.....IVDSSGPGVN.....NS
  13 ....EFVLR..KFGVMEPEL....IE.SA--.....-KGKEII.....LVDHSEKSQS.....FD
  14 ....SFINM..TFTNQIDES....FL.KE--.....---ALAI.....VVDANYKNRIelre.LL
  15 ....PWLEM..VFTPKEQIT....PE.LMQQ.....A---LAV.....IVDANYKERIecrd.LL
  16 ....RRLVA..LSRVPIEKD....PV.I---.....-KENVIF.....IFDTSSIEQL.....EP
  17 ....QHILN..VAGVEQPEL....RT.SVAG.....E---QVW.....LVDYTDLAQA.....PD
  18 ....ADGKD..LFPFEAAPI....DD.AFVK.....NS--LAI.....IFDTSNQERV.....LT
  19 ....EKFPY..IDKIEENPN....FD.PE--.....----LLV.....VVDASSPDRIgk...FQ
  20 ....SFLYS..LDEVDNETY....EG.A---.....----LVI.....VCDTANQERId....DQ
  21 ....KLSRN..ILNEIGERV....DI.EIYP.....KLPETVF.....IVDTASINQLkv...NF
  22 ....VPFKD..KFLSEWPNI....EI.SEY-.....----SVI.....ILDCSILDRIgde..FI
  23 ....DFLPG..VEDVINPDG....--.----.....KFYDVGI.....VVDASGFYRV.....GK
  24 ....RRLLK..FSRVPIERN....PK.I---.....-SERVVF.....IFDTSSLEQLe....PI
  25 ....NDFKN..FFTFDPNEV....DD.EFIK.....DS--IAF.....IVDTANQERV.....LS
  26 ....SDFLK..VYSDRFEFV....WD.HEFE.....GEITELV.....IVDAPSLDRIpes..IR
  27 ....RSLPG..CHLLVRPEV....MR.R---.....-DVDLVV.....TVDIPSVDRLgal..GD
  28 ....RQFLA..LHRNEFPLI....ELrSVNP.....DKIRSLY.....IVDNQQGDRLgkaadWL
  29 ....KRLLE..AVGEEFGPL....CS.PD--.....ENPLIAV.....VVDAANLSQIaga..ES
  30 ....KKYEE..LWSRFITPE....EA.MEIS.....NDDTLLV.....IVDTHKPSLV.....ME
  31 ....KKAGE..VFKKYRDKF....RV.IEDL.....PDCFELV.....LVDTHFLPEG.....LP
  32 ....KAMIN..LLGIKLLNV....E-.DIDL.....DNYCVIA.....VIDTSTSKQL.....PI
  33 ....SYLLN..LASISSDDI....VFlDDIV.....KLPKRIFsnpiyLVDHNSLDRK.....DL
  34 ....SFLPQ..PGELTAP--....LE.SWPQ.....GALAAVL.....DVDNNDPVRVa....GA
  35 ....IALVK..LTGLPAKRWgpqmLK.DIDL.....SDYQGCV.....LVDSQGTNSQlmp..LV
  36 ....REIAA..YATLFRPSL....SA.QIRP.....SDQTAVI.....VVDCSELSRVgae..LA
  37 s7dvMYVLE..KLKIKEEEL....FF.IEDL.....KSLKQNVsq9syLVDNNDTPKN.....LK
  38 s7dvMYVLE..KLKIKEEEL....FF.IEDL.....KSLKQNVsq9syLVDNNDTPKN.....LK
  39 ....FGLRN..DVTNLFKEL....GI.DASLl17iaALNASVV.....LYDHNKLREN.....QS
  40 ....SFLIDicLYNGIAVHL....DT.QTVP.....RMPDALV.....ILDTPNPGMIya7crLL
  41 ....LPLRG..DIVFFLQKV....HI.PESIl14yqAGQLTLI.....LVDHHILSKS.....DT
  42 ....-----..---------....--.----.....-------.....----------.....--


           90         100           110         120         130        
           |           |             |           |           |        
   1 DI..REVE.VVEVVDHH.RVANFET....ANPLYM.RLEPV.GSASSIVYRL..YKE.....NGV
   2 DI..REVE.VVEVVDHH.RVANFET....ANPLYM.RLEPV.GSASSIVYRL..YKE.....NGV
   3 DI..AEVE.VYGVVDHH.RVANFET....ANPLYM.RLEPV.GSASSIVYRM..FKE.....HSV
   4 DI..EEVQ.VLEVIDHH.RIANFET....AEPLYY.RAEPV.GCTATILNKM..YKE.....NNV
   5 GV..EKAE.ILEIIDHH.RLGGLST....LNPVFF.YNEPV.GSTSTIVAEF..FLK.....NGV
   6 GV..EKAE.ILEIIDHH.RLGGLST....LNPVFF.YNEPV.GSTSTIVAEF..FLK.....NGV
   7 QKh.KLAK.ETVRIDHH.PRTEK--....FADMEW.IDSSF.SATAEMIGYL..ILQ.....MGY
   8 EE..DLNK.IEIIIDHH.QILQNLReklpPNCFVD.IRTDV.NATSSIMAEY..LKA.....LEI
   9 GI..DKAE.VVAIVDHH.KIGDVTT....PQPILF.VNLPV.GCTATVIKLL..FDK.....TGV
  10 AL..GELD.VTRVVDHH.KLGDLTT....INPPYL.RFEPV.GCTGTILLKL..HRE.....AGL
  11 DD..DLKR.VEIIVDHH.QILQNLReklsPNCFVD.IRTDV.NATSSIMVEY..LKA.....LEI
  12 IP..PDID.ISIVIDHH.PAEKV--....VAEFVD.LREDV.GATATILTEY..IKE.....LKI
  13 DL..EEGK.LIAIIDHH.KVG-LTT....TEPILY.YAKPV.GSTATVIAEL..YFKda8ggKKK
  14 DK..NLFK.AVLRIDHH.PNEDD-L....NTSFNF.VEESY.VACCEQIVEM..ATV.....AKW
  15 DQ..NQFK.AVLRIDHH.PNEDD-L....NTTHNF.VDASY.IAAAEQVVDL..AVQ.....AKW
  16 IE..VPPA.KIVVIDHH.VEKENPI....PADVAI.IDPTR.TSTAEIVWEL..FKK.....FNY
  17 DL..NQAE.ILGIVDHH.RLGDVMT....VNPLEA.WIWPV.GCTSTILFNL..FKM.....ENA
  18 QKh.KLAK.ETVRIDHH.PKTES--....FADLEW.IDPAF.SAAAEMVGYL..ILQ.....MGY
  19 DL..LDKV.PSVVIDHH.STNTN--....FGNWNW.VDPSF.AATAQMIFRI..NKA.....LGV
  20 RY..PSGA.KLMKIDHH.PNEDP--....YGDLLW.VDTSA.SSVSEMIYEL..YLEgke..HGW
  21 DE..LKER.EVILIDHH.KKTDLAD....ICKYYI.IKEDY.PSTSEIIAEI..FKE.....LNI
  22 FY..VKNM.PTLVIDHH.MSGEKLE....CEG--Y.IDPFA.PSTTFLIEKL..IRE.....FGH
  23 EV..-KVG.KRIRIDHH.VGGEFYG....MHD--Y.IDPTA.PATAALVYEI..IKN.....WDE
  24 KI..PPNA.KLIVIDHH.VEKENPI....PADISV.IDPKR.TSTAEIVWEL..FKK.....LGY
  25 QKh.RLAK.KTILVDHH.VKT--IT....YTDLEY.INDQS.IAACEMIAYS..LMH.....TNL
  26 KK..AQGA.KITVYDHH.VDE----....-SPYDG.IVSKV.GATITILVEL..IRE.....KNI
  27 LT..DSGR.ELLVIDHH.ASNDL--....FGTANF.IDPSA.DSTTTMVAEI..LDA.....WGK
  28 TL..PHLR.QVAIYDHH.LNSPRDI....EADI-W.ELEAV.GASTTLIVEK..LQR.....ADI
  29 LF..RAAR.LKVVIDHH.ERGSIHE....EADVAL.VDPGA.GSSSELAVKT..AVE.....AGT
  30 ERlvNKIE.HIVVIDHH.RRGEEFI....RDPLLV.YMEPYaSSTAELVTELleYQP.....KRL
  31 RE..R-IK.RIIVYDHH.PIGDV--....-KEFEG.KIEKV.GAATTLVVEE..IKE.....KGI
  32 EL..PNI-.-DIIIDHH.NNTDL--....TAKYMD.VRPEV.GATASILTQY..LME.....LDI
  33 EN..FNGS.IAGIIDHH.KDEGGSL....HADP-R.IIEEC.GSCCTLVCRY..FMP.....VIR
  34 DL..TQFDgPVVNVDHH.GTN--LR....RADAGV.VDPSK.PAAAMMVADV..IDA.....LGA
  35 QE..ANIP.VVVIIDHHsPQDEVEA....EGAFVD.IRPSS.RSTATILTEY..LQG.....GML
  36 SQ..LAPF.ARAFIDHH.ETCGDHC....AHS--F.VVKTA.PSTTTLVQTL..IET.....MAG
  37 NY..IDN-.VVGIIDHH.FDLQKHL....DAEP-R.IVKVS.GSCSSLVFNY..WYEklq..GDR
  38 NY..IDN-.VVGIIDHH.FDLQKHL....DAEP-R.IVKVS.GSCSSLVFNY..WYEklq..GDR
  39 DL..AS-R.VVGVVDHH.FDEQQYLk...TASKLR.VLRTV.GSACTLVTEL..YRE.....CGE
  40 LS..DSTI.RKIELDHH.LFANAAC....CGDPGYsLIARA.SSTCEIIAYL..CYK.....LAR
  41 AL..EEA-.VAEVLDHR.PIEPKHC....PPCH-V.SVELV.GSCATLVTER..ILQ.....GAP
  42 --..----.--------.-------....FADMEW.IDSSF.SATAEMIGYL..ILQ.....MGY


                140       150         160       170       180
                 |         |           |         |         |
   1 A.IPK.....EIAGVMLSGLISDTLLL..KSPTTHASDPAVAEDLAKIAGVDLQE
   2 A.IPK.....EIAGVMLSGLISDTLLL..KSPTTHASDPAVAEDLAKIAGVDLQE
   3 A.VSK.....EIAGLMLSGLISDTLLL..KSPTTHPTDKAIAPELAELAGVNLEE
   4 K.IEK.....EIAGLMLSAIISDSLLF..KSPTCTDQDVAAAKELAEIAGVDAEE
   5 K.MER.....EIAGILLSGIVSDTLFF..KLSTTTEKDRKMANFLADVAKLDLE-
   6 K.MER.....EIAGILLSGIVSDTLFF..KLSTTTEKDRKMANFLADVAKLDLE-
   7 K.LND.....EIASYLYAGIITDTQRF..WGPTTTPQTFALTAKLME--------
   8 P.ITE.....TLATALFYGMYIDTKKF..SK--LSRVDINAIEFLTGKVNYELLD
   9 E.IPK.....DIAGILLSSILSDTVIF..KSATTTELDKEVAEELAKIAGIDD--
  10 S.VEP.....QDAKLMLSAILSDTLHF..RSPTTTQDDRDAVAFLAPVAGVNDV-
  11 P.ITD.....TLATALFYGMYIDTKKF..SK--LSRVDISAIEFLTGKVNYELLD
  12 T.PSK.....ILATALFFGIKSETDEF..KR-NTRTADFLACAFLYPFVDQDLIE
  13 E.LKP.....DLAGLLLSAIISDTVLF..KSPTTTDLDKEMAKKLAEIAGISNI-
  14 T.IPP.....VAATLLYIGIYTDSNRF..LYSNTSYRTLYLAAILYK--------
  15 K.LSP.....PAATALYLGIYTDSNRF..LYSNTSWRTLYLGSMLY---------
  16 S.-DE.....NSAKALLAGIISDTSNF..RY--ANAKTFKAVYEILELYDFSIPE
  17 E.ITR.....PLALLMISAILSDTVGF..ASPTCTQKDRDAVAELAVLAGITDL-
  18 E.LNA.....EMAAYIYAGIITDTQRF..SSSATTPQTFALTAKLLE--------
  19 E.YDS.....NLATLNYLGIATDTGFF..RHSNADVRVFEDAYKLVK--------
  20 K.LNT.....KAAELIYAGIVGDTGRF..LFPNTTEKTLKYAGELIQ--------
  21 F.PPK.....NVRIALLCGIVYDTKHL..KL--ANSKTFELISYLIKDIS-----
  22 D.LTK.....EEAWYILVGFCTDTGFF..KF--ISRSDPEPFEMVARLVS-----
  23 TaIDK.....DIATCIYTGLATDTGFF..RYSNTNEKTFELAKELVS--------
  24 K.-DE.....DSAKVLLAAIISDTSSF..RY--ANAKTFKTVSEILELYDFSIS-
  25 N.FDL.....KTLNYLLLGITTDSNRL..MYDKVSDFTYEIMSWFF---------
  26 P.LDP.....TEATLFMIALYDDTGNL..LFSSTTPRDLEIAKFLLE--------
  27 P.IDP.....RVAHCIYAGLATDTGSF..RW--ASVRGYRLAARLVE--------
  28 S.LSM.....VEASVMALGIHVDTGSL..TFTQTTVRDVKALAWLME--------
  29 P.LRP.....SVATAALGGIVYDTGRF..LR--ASKLSFEAAAHLLS--------
  30 K.INM.....IEATALLAGIIVDTKSF..SL-RTGSRTFDAASYL----------
  31 D.INP.....RDATLLAFGIYEDTGNF..TYEGTTPRDALALAFLLE--------
  32 E.PSR.....NLATALFYGIQSDTDYF..KR-ETSKLDFEAAAYLQSYIDASIL-
  33 S.LYDs11atNLAVLALGPILIDTGNL..KNEKTTDTDVKIVNDLCSFVPKDWV-
  34 P.WSE.....AVATPLMLGLNTDTGNF..AFDSVSAETFECAARL----------
  35 D.FNSsn6hvKCATALMHGLRSDTINL..LQ--AQEAEFMAAAYLSRIYDAQLL-
  36 S.LEA.....AEARALFLGLATDTGFF..RHLDEHS-------------------
  37 E.VVM.....NIALLLMGAILIDTSNM..RR-KVEESDKLAIE------------
  38 E.VVM.....NIAPLLMGAILIDTSNM..RR-KVEESDKLAIE------------
  39 D.V--.....VCPTLLTAPIVLDTVNFepAQKKVTPEDIAAYEWL----------
  40 N.HAQ.....RTAL-------------..--------------------------
  41 EiLDR.....QTAALLHGTIILDCVNMdlKIGKATPKDSKYVEKL----------
  42 K.LND.....EIASYLYAGIITDTQRF..WGPTTTPQTFALTAKLME--------