;  SAM: prettyalign v3.2 (July 31, 2000) compiled 08/11/00_16:27:51
;  (c) 1992-2000 Regents of the University of California, Santa Cruz
;
;          Sequence Alignment and Modeling Software System
;         http://www.cse.ucsc.edu/research/compbio/sam.html
;
; ----------------- Citations (SAM, SAM-T99, HMMs) --------------------
; R. Hughey, A. Krogh, Hidden Markov models for sequence analysis:
;  Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
; K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting
;  remote protein homologies, Bioinformatics 14(10):846-856, 1999.
; A. Krogh et al., Hidden Markov models in computational biology:
;  Applications to protein modeling, JMB 235:1501-1531, Feb 1994.
; ---------------------------------------------------------------------
; Sequences correspond to the following labels:
; 1 RECJ_ECOLI/382-451
; 2 RECJ_ERWCH/381-449
; 3 RECJ_HAEIN/376-445
; 4 P73518/390-455
; 5 O32044/370-436
; 6 O83702/514-575
; 7 Q9Z7Z0/390-454
; 8 P94659/317-381
; 9 O84453/389-453
; 10 Q9ZD22/386-452
; 11 Q9ZMA0/338-403
; 12 O67909/370-434
; 13 Y371_MYCGE/252-315
; 14 O51269/507-572
; 15 Q9ZM41/283-342
; 16 O67552/249-312
; 17 O51564/262-322
; 18 O83450/285-343
; 19 P71615/275-333
; 20 MGPA_MYCPN/261-317
; 21 MGPA_MYCGE/296-360
; 22 O31824/247-305
; 23 YG33_METJA/394-461
; 24 O58017/401-472
; 25 O28250/387-458
; 26 Y988_METJA/239-310
; 27 O73979/249-318
; 28 Y977_METJA/396-466
; 29 O26266/371-441
; 30 O57804/392-465
; 31 O29523/379-449
; 32 O27473/379-449
; 33 O29559/362-431
; 34 Y831_METJA/355-424
; 35 YYBT_BACSU/588-647
; 36 O66728/230-290
; 37 O58035/847-912
; 38 SYA_ARCFU/831-899
; 39 O67323/793-863
; 40 SYA_THIFE/800-870
; 41 SYA_ECOLI/799-869
; 42 SYA_BACSU/801-872
; 43 SYA_HAEIN/798-868
; 44 SYA_BARBA/810-882
; 45 SYA_SYNY3/797-870
; 46 Q9ZCA4/802-873
; 47 SYA_METJA/829-887
; 48 Q9Z714/793-865
; 49 O84754/846-917
; 50 O57734/333-400
; 51 SYAC_SCHPO/881-951
; 52 SYAC_YEAST/877-950
; 53 SYA_METTH/817-891
; 54 SYA_THETH/808-882
; 55 SYA_MYCTU/821-895
; 56 O01541/890-961
; 57 SYA_HUMAN/886-957
; 58 SYA_BOMMO/889-960
; 59 SYA_HELPY/772-839
; 60 SYA_ARATH/923-996
; 61 RECJ_ECOLI/382-451
; 62 RECJ_ERWCH/381-449
; 63 RECJ_HAEIN/376-445
; 64 P73518/390-455
; 65 O32044/370-436
; 66 O83702/514-575
; 67 Q9Z7Z0/390-454
; 68 P94659/317-381
; 69 O84453/389-453
; 70 Q9ZD22/386-452
; 71 Q9ZMA0/338-403
; 72 O67909/370-434
; 73 Y371_MYCGE/252-315
; 74 O51269/507-572
; 75 Q9ZM41/283-342
; 76 O67552/249-312
; 77 O51564/262-322
; 78 O83450/285-343
; 79 P71615/275-333
; 80 MGPA_MYCPN/261-317
; 81 MGPA_MYCGE/296-360
; 82 O31824/247-305
; 83 YG33_METJA/394-461
; 84 O58017/401-472
; 85 O28250/387-458
; 86 Y988_METJA/239-310
; 87 O73979/249-318
; 88 Y977_METJA/396-466
; 89 O26266/371-441
; 90 O57804/392-465
; 91 O29523/379-449
; 92 O27473/379-449
; 93 O29559/362-431
; 94 Y831_METJA/355-424
; 95 YYBT_BACSU/588-647
; 96 O66728/230-290
; 97 O58035/847-912
; 98 SYA_ARCFU/831-899
; 99 O67323/793-863
; 100 SYA_THIFE/800-870
; 101 SYA_ECOLI/799-869
; 102 SYA_BACSU/801-872
; 103 SYA_HAEIN/798-868
; 104 SYA_BARBA/810-882
; 105 SYA_SYNY3/797-870
; 106 Q9ZCA4/802-873
; 107 SYA_METJA/829-887
; 108 Q9Z714/793-865
; 109 O84754/846-917
; 110 O57734/333-400
; 111 SYAC_SCHPO/881-951
; 112 SYAC_YEAST/877-950
; 113 SYA_METTH/817-891
; 114 SYA_THETH/808-882
; 115 SYA_MYCTU/821-895
; 116 O01541/890-961
; 117 SYA_HUMAN/886-957
; 118 SYA_BOMMO/889-960
; 119 SYA_HELPY/772-839
; 120 SYA_ARATH/923-996
; 121 gi|7450701|pir||E69056_377:449
; 122 gi|7475820|pir||H69980_370:436
; 123 gi|1172895|sp|P45112|RECJ_HAEIN_376:445
; 124 gi|9656991|gb|AAF95560.1|_385:454
; 125 gi|6707750|sp|Q9Z714|SYA_CHLPN_794:865
; 126 gi|135089|sp|P21894|SYA_BOMMO_888:960
; 127 gi|2126389|pir||PC4257_66:130
; 128 gi|7190761|gb|AAF39542.1|_389:453
; 129 gi|7450703|pir||G75192_393:465
; 130 gi|3063673|gb|AAC14136.1|_317:381
; 131 gi|6226165|sp|O67323|SYA_AQUAE_793:863
; 132 gi|96357|pir||C39202_383:450
; 133 gi|2833617|sp|Q58241|Y831_METJA_355:424
; 134 gi|2507106|sp|P21893|RECJ_ECOLI_382:449
; 135 gi|7190160|gb|AAF39003.1|_798:866
; 136 gi|6707748|sp|Q9XDM3|SYA_AQUPY_795:863
; 137 gi|7450705|pir||G69341_379:448
; 138 gi|7500106|pir||T29466_889:958
; 139 gi|7451685|pir||A70485_370:434
; 140 gi|3183171|sp|O13914|SYAC_SCHPO_881:951
; 141 gi|2507107|sp|P39693|RECJ_ERWCH_381:447
; 142 gi|7518105|pir||C75065_253:316
; 143 gi|7451688|pir||H71513_389:452
; 144 gi|7450704|pir||H71224_392:464
; 145 gi|7451687|pir||D72062_390:453
; 146 gi|7445472|pir||F70440_254:312
; 147 gi|4501841|ref|NP_001596.1|_886:954
; 148 gi|7451686|pir||G71656_386:452
; 149 gi|609338|gb|AAC49007.1|_877:948
; 150 gi|6324911|ref|NP_014980.1|_877:948
; 151 gi|7297398|gb|AAF52657.1|_888:956
; 152 gi|7450700|pir||B69086_373:440
; 153 gi|6707747|sp|O84754|SYA_CHLTR_798:867
; 154 gi|6176442|gb|AAF05593.1|AF188718_1_888:956
; 155 gi|7518694|pir||B71167_252:315
; 156 gi|7437632|pir||E71476_847:916
; 157 gi|1174496|sp|P43815|SYA_HAEIN_800:866
; 158 gi|9654973|gb|AAF93713.1|_786:852
; 159 gi|2496410|sp|P75229|Y371_MYCPN_256:315
; 160 gi|7226845|gb|AAF41948.1|_797:865
; 161 gi|7226077|gb|AAF41253.1|_378:444
; 162 gi|7379749|emb|CAB84317.1|_378:444
; 163 gi|7453624|gb|AAF62912.1|_378:444
; 164 gi|3122886|sp|O34526|SYA_BACSU_802:868
; 165 gi|2281029|dbj|BAA21554.1|_2:65
; 166 gi|6707752|sp|Q9X1B6|SYA_THEMA_792:859
; 167 gi|7380429|emb|CAB85015.1|_797:862
; 168 gi|6967975|emb|CAB75143.1|_770:832
; 169 gi|6967533|emb|CAB72521.1|_338:400
; 170 gi|7463775|pir||F70131_509:570
; 171 gi|2842584|sp|Q58387|RECJ_METJA_398:463
; 172 gi|7462295|pir||G72233_250:306
; 173 gi|6899351|gb|AAF30778.1|AE002134_2_827:899
; 174 gi|6707753|sp|Q9ZJY5|SYA_HELPJ_771:836
; 175 gi|3122879|sp|O07438|SYA_MYCTU_822:892
; 176 gi|6899406|gb|AAF30828.1|AE002139_1_253:310
; 177 gi|7521421|pir||D71289_514:572
; 178 gi|7450702|pir||C69337_362:430
; 179 gi|2496409|sp|Q49428|Y371_MYCGE_256:315
; 180 gi|145220|gb|AAA03208.1|_800:863
; 181 gi|2507425|sp|P00957|SYA_ECOLI_800:863
; 182 gi|3024653|sp|P56452|SYA_HELPY_771:836
; 183 gi|3334348|sp|O28029|SYA_ARCFU_831:898
; 184 gi|2500959|sp|P74423|SYA_SYNY3_798:867
                       10        20           30         40         50 
                       |         |            |          |          | 
   1 ........HRPVIAFA.-PAGDGTLKGSGRSIQ.G.LHM.R--DAL.ERLDTLYPGMMLKFG.GH
   2 ........HRPVIAFA.-PAGDGILKGSGRSIA.G.L--.-HLHAL.ERLDTCHPGLMLKFG.GH
   3 ........HRPVIAFA.-QDSEGILKGSARSIE.G.LHM.R--DVL.ERIHSQHPNMILKFG.GH
   4 g.......-RPAILLN.-TQDGKIAKGSARSVA.-.---.-NIDLY.ALLHSQRHLM-LGFG.GH
   5 y.......-RPAIVLG.IDEEKGIAKGSARSIR.-.---.-GFNLF.ESLSECRDIL-PHFG.GH
   6 v.......------II.CIMADGHAVGSLRSAR.-.---.-GYHLF.SLLDPLADLF-SDYG.GH
   7 n.......-KPVVIIA.--IQRGIGKGSARTIG.-.---.-SFPLL.GVLKKCSSLL-LSYG.GH
   8 nk......--PVAII-.-SNQGGVGKGSLRTIG.-.---.-SFPLL.GILQKCSSLF-ISYG.GH
   9 n.......-KPVAIIA.--LQDGIGKGSLRTIG.-.---.-SFPLL.GVLRKCESFF-LSYG.GH
  10 ........DKPVVVVA.--LNNGIGKASCRSIL.-.---.-GIDFSaEIINAKSKDLIISGG.GH
  11 qkps....------LV.FTFKEGVYKGSARSSP.-.---.-NIDLI.DALNGVSSLL-LGYG.GH
  12 ........NKPVAVFS.--KGKTKAVGSIRSIE.-.---.-SIDVY.DKVSTMRDMF-LKWG.GH
  13 kgv.....-KIWTTVY.FNESIKKWIGSIRSRN.-.---.--IPIN.NFAQM------FNGG.GH
  14 qkv.....-----AIF.LTKQDNIIKGSIRSNN.-.---.-KINSK.TLISIIPSHLVINSG.GH
  15 fyi.....--------.--DVNSKGNVSLRANG.-.---.-NCDVC.ELSQMC-----FNGG.GH
  16 egv.....-KVAYALI.EKPEEGVWKVSLRAKG.-.---.-NVNVG.KIAER------LGGG.GH
  17 ne......---ILGIL.KEMEDGSIIVGLRSKD.-.---.-SFDVG.KLAED------FGGG.GH
  18 e.......---AIVVV.RQESPTHCSVGFRSRG.-.---.-SIDVS.VIAAR------FGGG.GH
  19 aev.....----AAVF.KEVEPHRWSVSMRAKT.-.---.--VNLA.AVASG------FGGG.GH
  20 h.......---IWLFF.IEEGKNHYRVEFRSNG.-.---.--INVR.EVALK------YGGG.GH
  21 yk......---IWLFF.IEQANNEIRIDLRSNG.-.---.--INVR.DIAIK------YGGG.GH
  22 ldy12gsk--------.--------RVSLRTIH.-.---.DYIDVS.EIAGR------YGGG.GH
  23 ist.....-----TFV.FGIVGDEIHISARTKD.-.---.LRLNLG.EILNKA-----FGGG.GH
  24 it......----TVLV.FGIVDDRIEISARTRD.-.---.VRVNIG.NVMKEAFGEI-GSGG.GH
  25 is......----TVVV.FGVIKDTVYVSARNKD.-.---.VRIHMG.EVLRRAFGDV-GSAG.GH
  26 ad......--VAFVVA.VRKKEKEIRVSARCRK.-.HVS.KYVHLG.NLMEKIGKELGGSGG.GH
  27 adv.....------AI.VGSEKDGVRISARAKD.Y.LVK.QGLHLG.KIMEKVGPIIKGSGG.GH
  28 mkp.....-----IFA.ITEDENGYKVSARCPK.L.LCFaEDVNLA.KAIKYASEKVNGSGG.GH
  29 rrpm....----IGLG.--ETADGLKVSLRCSR.L.LAF.DGIHFG.SIMRRVAEKVGGSGG.GH
  30 e.......-KPVIVFAdTDEDPNLIKGSARTTE.K.ALE.RGYHLG.EALRKAAEIIGGEGG.GH
  31 ........EKPIIAFA.--ESDKGVKVSARATY.R.LVE.RGVHLA.KALKRAAEAVGGVGG.GH
  32 dip.....-----LLG.LSRMDQHVKVSARTTR.P.AVE.RGVNLG.VALRDAAASFGGTGG.GH
  33 ........DKPLIVVN.--IKNEYAKVSARTNE.A.LAE.R-VDLA.EVMRLAAEKVGGRGG.GH
  34 ........DKPVIGYH.--IEGDIAKFSARGNR.D.LVN.RGLNLS.VAMAV-AKEFGGNGG.GH
  35 easfa...-------V.ARRDEQTVCISARSLG.-.---.-EVNVQ.IIMEA------LEGG.GH
  36 sda.....-----FFV.IIEAEGKTYVFGRSQS.-.---.EDVDVG.EILSH------FGGG.GH
  37 kr......-----VVV.LISRDGYFAVSVGSEV.-.---.-GVEAN.ELAKKITLIAGGGGG.GR
  38 ........EKGAVGCL.MAKGEGKVFVVTFSGQ.-.---.-KYDAR.ELLREIGRVAKGSGG.GR
  39 kd......----VVFI.ASRKGDKINFVIGVSK.E.ISD.K-VNAK.EVIREVGKVLKGGGG.GR
  40 dgv.....-----IVL.AGVEREKVALIAGVGK.G.LTG.R-VHAG.ELVNTVAQPLGGKGG.GR
  41 st......----IIVL.ATVVEGKVSLIAGVSK.D.VTD.R-VKAG.ELIGMVAQQVGGKGG.GR
  42 sa......----VIVL.GAVQNDKVNISAGVTK.D.LIE.KGLHAG.KLVKQAAEVCGGGGG.GR
  43 sgv.....-----IAF.ASILDEKVNLVVGVTN.D.LTA.K-IKAG.ELVNLMAQQVGGKGG.GR
  44 sg......---VVAFI.SVSEDGKGSAVVGVTD.D.LTD.T-LNAV.DLVRIISVTLGGQGGgGR
  45 es......--AVVLAS.IPEEGKVSLVAAFSPQ.L.VKT.KQLKAG.QFIGAIAKICGGGGG.GR
  46 n.......---LIVVY.IAHGVDKLSITVAVSK.A.ITD.K-FNAG.IIAKELSLFLGGSGGgGQ
  47 na......----IVVL.LNDKGNILCKRGENVD.-.---.--IKMN.ELIRYI-----AKGG.GR
  48 ek......---LISLW.TTEKNGKYIVLSRVSD.D.LIT.QGVHAQ.DLLKAVLTPCGGRWG.GK
  49 nf......----ISLW.ITEKNGRYIVLSRVSD.D.LTK.RGVQAH.TLLAELLAPYGGRCG.GK
  50 sntilll.--------.---ANEKYVLFAKNEG.-.---.VPVSMR.ELLKEVIDELGGKGG.GT
  51 ........DKSIYLLA.--SDDTKVAHACLVSP.E.AMK.K-LTPQ.EWSQKVCHSIGGRSG.GK
  52 ........DKSIYLLA.GNDPEGRVAHGCYISN.A.ALA.KGIDGS.ALAKKVSSIIGGKAG.GK
  53 lelsa...----TVDA.VVLANPEGKIVGAASE.D.AVK.AGLRIN.EVISQAAAVLGGGGG.GR
  54 ddl22vlk--------.-------------LSP.K.AQG.MGLEAG.ALFRALAEKAGGRGG.GK
  55 s.......EPAVVALI.AEGESQTVPYAVAANP.A.AQD.LGIRAN.DLVKQLAVAVEGRGG.GK
  56 a.......---VMAFS.VNEDSGKVLCLAKVDK.S.LVS.NGLKAN.EWVNEVCTVLGGKGG.GK
  57 s.......---AMLFT.VDNEAGKITCLCQVPQ.N.AAN.RGLKAS.EWVQQVSGLMDGKGG.GK
  58 a.......---AMFFS.VDKDADKIYCLAAVPK.S.DVE.KGLLAS.EWVQSVVDIIGGKGG.GK
  59 rll.....-----AMV.FKKENERITLACGVKN.-.---.APIKAN.VWANEVAQILGGKGG.GR
  60 s.......---IMVFS.TDESTNKAVVCAGVPEkS.DQF.KPLDVT.EWLTTALGPLKGRCGkGK
  61 ........HRPVIAFA.-PAGDGTLKGSGRSIQ.G.LHM.R--DAL.ERLDTLYPGMMLKFG.GH
  62 ........HRPVIAFA.-PAGDGILKGSGRSIA.G.L--.-HLHAL.ERLDTCHPGLMLKFG.GH
  63 ........HRPVIAFA.-QDSEGILKGSARSIE.G.LHM.R--DVL.ERIHSQHPNMILKFG.GH
  64 g.......-RPAILLN.-TQDGKIAKGSARSVA.-.---.-NIDLY.ALLHSQRHLM-LGFG.GH
  65 y.......-RPAIVLG.IDEEKGIAKGSARSIR.-.---.-GFNLF.ESLSECRDIL-PHFG.GH
  66 v.......------II.CIMADGHAVGSLRSAR.-.---.-GYHLF.SLLDPLADLF-SDYG.GH
  67 n.......-KPVVIIA.--IQRGIGKGSARTIG.-.---.-SFPLL.GVLKKCSSLL-LSYG.GH
  68 nk......--PVAII-.-SNQGGVGKGSLRTIG.-.---.-SFPLL.GILQKCSSLF-ISYG.GH
  69 n.......-KPVAIIA.--LQDGIGKGSLRTIG.-.---.-SFPLL.GVLRKCESFF-LSYG.GH
  70 ........DKPVVVVA.--LNNGIGKASCRSIL.-.---.-GIDFSaEIINAKSKDLIISGG.GH
  71 qkps....------LV.FTFKEGVYKGSARSSP.-.---.-NIDLI.DALNGVSSLL-LGYG.GH
  72 ........NKPVAVFS.--KGKTKAVGSIRSIE.-.---.-SIDVY.DKVSTMRDMF-LKWG.GH
  73 kgv.....-KIWTTVY.FNESIKKWIGSIRSRN.-.---.--IPIN.NFAQM------FNGG.GH
  74 qkv.....-----AIF.LTKQDNIIKGSIRSNN.-.---.-KINSK.TLISIIPSHLVINSG.GH
  75 fyi.....--------.--DVNSKGNVSLRANG.-.---.-NCDVC.ELSQMC-----FNGG.GH
  76 egv.....-KVAYALI.EKPEEGVWKVSLRAKG.-.---.-NVNVG.KIAER------LGGG.GH
  77 ne......---ILGIL.KEMEDGSIIVGLRSKD.-.---.-SFDVG.KLAED------FGGG.GH
  78 e.......---AIVVV.RQESPTHCSVGFRSRG.-.---.-SIDVS.VIAAR------FGGG.GH
  79 aev.....----AAVF.KEVEPHRWSVSMRAKT.-.---.--VNLA.AVASG------FGGG.GH
  80 h.......---IWLFF.IEEGKNHYRVEFRSNG.-.---.--INVR.EVALK------YGGG.GH
  81 yk......---IWLFF.IEQANNEIRIDLRSNG.-.---.--INVR.DIAIK------YGGG.GH
  82 ldy12gsk--------.--------RVSLRTIH.-.---.DYIDVS.EIAGR------YGGG.GH
  83 ist.....-----TFV.FGIVGDEIHISARTKD.-.---.LRLNLG.EILNKA-----FGGG.GH
  84 it......----TVLV.FGIVDDRIEISARTRD.-.---.VRVNIG.NVMKEAFGEI-GSGG.GH
  85 is......----TVVV.FGVIKDTVYVSARNKD.-.---.VRIHMG.EVLRRAFGDV-GSAG.GH
  86 ad......--VAFVVA.VRKKEKEIRVSARCRK.-.HVS.KYVHLG.NLMEKIGKELGGSGG.GH
  87 adv.....------AI.VGSEKDGVRISARAKD.Y.LVK.QGLHLG.KIMEKVGPIIKGSGG.GH
  88 mkp.....-----IFA.ITEDENGYKVSARCPK.L.LCFaEDVNLA.KAIKYASEKVNGSGG.GH
  89 rrpm....----IGLG.--ETADGLKVSLRCSR.L.LAF.DGIHFG.SIMRRVAEKVGGSGG.GH
  90 e.......-KPVIVFAdTDEDPNLIKGSARTTE.K.ALE.RGYHLG.EALRKAAEIIGGEGG.GH
  91 ........EKPIIAFA.--ESDKGVKVSARATY.R.LVE.RGVHLA.KALKRAAEAVGGVGG.GH
  92 dip.....-----LLG.LSRMDQHVKVSARTTR.P.AVE.RGVNLG.VALRDAAASFGGTGG.GH
  93 ........DKPLIVVN.--IKNEYAKVSARTNE.A.LAE.R-VDLA.EVMRLAAEKVGGRGG.GH
  94 ........DKPVIGYH.--IEGDIAKFSARGNR.D.LVN.RGLNLS.VAMAV-AKEFGGNGG.GH
  95 easfa...-------V.ARRDEQTVCISARSLG.-.---.-EVNVQ.IIMEA------LEGG.GH
  96 sda.....-----FFV.IIEAEGKTYVFGRSQS.-.---.EDVDVG.EILSH------FGGG.GH
  97 kr......-----VVV.LISRDGYFAVSVGSEV.-.---.-GVEAN.ELAKKITLIAGGGGG.GR
  98 ........EKGAVGCL.MAKGEGKVFVVTFSGQ.-.---.-KYDAR.ELLREIGRVAKGSGG.GR
  99 kd......----VVFI.ASRKGDKINFVIGVSK.E.ISD.K-VNAK.EVIREVGKVLKGGGG.GR
 100 dgv.....-----IVL.AGVEREKVALIAGVGK.G.LTG.R-VHAG.ELVNTVAQPLGGKGG.GR
 101 st......----IIVL.ATVVEGKVSLIAGVSK.D.VTD.R-VKAG.ELIGMVAQQVGGKGG.GR
 102 sa......----VIVL.GAVQNDKVNISAGVTK.D.LIE.KGLHAG.KLVKQAAEVCGGGGG.GR
 103 sgv.....-----IAF.ASILDEKVNLVVGVTN.D.LTA.K-IKAG.ELVNLMAQQVGGKGG.GR
 104 sg......---VVAFI.SVSEDGKGSAVVGVTD.D.LTD.T-LNAV.DLVRIISVTLGGQGGgGR
 105 es......--AVVLAS.IPEEGKVSLVAAFSPQ.L.VKT.KQLKAG.QFIGAIAKICGGGGG.GR
 106 n.......---LIVVY.IAHGVDKLSITVAVSK.A.ITD.K-FNAG.IIAKELSLFLGGSGGgGQ
 107 na......----IVVL.LNDKGNILCKRGENVD.-.---.--IKMN.ELIRYI-----AKGG.GR
 108 ek......---LISLW.TTEKNGKYIVLSRVSD.D.LIT.QGVHAQ.DLLKAVLTPCGGRWG.GK
 109 nf......----ISLW.ITEKNGRYIVLSRVSD.D.LTK.RGVQAH.TLLAELLAPYGGRCG.GK
 110 sntilll.--------.---ANEKYVLFAKNEG.-.---.VPVSMR.ELLKEVIDELGGKGG.GT
 111 ........DKSIYLLA.--SDDTKVAHACLVSP.E.AMK.K-LTPQ.EWSQKVCHSIGGRSG.GK
 112 ........DKSIYLLA.GNDPEGRVAHGCYISN.A.ALA.KGIDGS.ALAKKVSSIIGGKAG.GK
 113 lelsa...----TVDA.VVLANPEGKIVGAASE.D.AVK.AGLRIN.EVISQAAAVLGGGGG.GR
 114 ddl22vlk--------.-------------LSP.K.AQG.MGLEAG.ALFRALAEKAGGRGG.GK
 115 s.......EPAVVALI.AEGESQTVPYAVAANP.A.AQD.LGIRAN.DLVKQLAVAVEGRGG.GK
 116 a.......---VMAFS.VNEDSGKVLCLAKVDK.S.LVS.NGLKAN.EWVNEVCTVLGGKGG.GK
 117 s.......---AMLFT.VDNEAGKITCLCQVPQ.N.AAN.RGLKAS.EWVQQVSGLMDGKGG.GK
 118 a.......---AMFFS.VDKDADKIYCLAAVPK.S.DVE.KGLLAS.EWVQSVVDIIGGKGG.GK
 119 rll.....-----AMV.FKKENERITLACGVKN.-.---.APIKAN.VWANEVAQILGGKGG.GR
 120 s.......---IMVFS.TDESTNKAVVCAGVPEkS.DQF.KPLDVT.EWLTTALGPLKGRCGkGK
 121 ........DPDIPLLG.LSRMDQHVKVSARTTR.P.AVE.RGVNLG.VALRDAAASFGGTGG.GH
 122 ........YRPAIVLG.IDEEKGIAKGSARSIR.-.---.-GFNLF.ESLSECRDIL-PHFG.GH
 123 ........HRPVIAFA.-QDSEGILKGSARSIE.G.LHM.R--DVL.ERIHSQHPNMILKFG.GH
 124 ........HRPVIAFA.-EGGDGKLKGSCRSVP.G.LHM.R--DAL.DKIDTQNPGIILKFG.GH
 125 ........--KLISLW.TTEKNGKYIVLSRVSD.D.LIT.QGVHAQ.DLLKAVLTPCGGRWG.GK
 126 ........-SAAMFFS.VDKDADKIYCLAAVPK.S.DVE.KGLLAS.EWVQSVVDIIGGKGG.GK
 127 ........NKPVAIIS.--NQGGVGKGSLRTIG.-.---.-SFPLL.GILQKCSSLF-ISYG.GH
 128 ........NKPVAIIA.--LQDGIGKGSLRTIG.-.---.-AFPLL.GVLRKCESFF-LSYG.GH
 129 ........EKPVIVFAdTDEDPNLIKGSARTTE.K.ALE.KGYHLG.EALKKAAEMIGGEGG.GH
 130 ........NKPVAIIS.--NQGGVGKGSLRTIG.-.---.-SFPLL.GILQKCSSLF-ISYG.GH
 131 ........--KDVVFI.ASRKGDKINFVIGVSK.E.ISD.K-VNAK.EVIREVGKVLKGGGG.GR
 132 ........HRPVIAFA.-PAGDGTLKGSGRSIQ.G.LHM.R--DAL.ERLDTLYPGMMLKFG.GH
 133 ........DKPVIGYH.--IEGDIAKFSARGNR.D.LVN.RGLNLS.VAMAV-AKEFGGNGG.GH
 134 ........HRPVIAFA.-PAGDGTLKGSGRSIQ.G.LHM.R--DAL.ERLDTLYPGMMLKFG.GH
 135 ........---FISLW.VTEKNDRYIVLVRVSD.D.LVK.QGIDAQ.ALLEELLAPYGGRCG.GK
 136 ........----VVFI.ASKKEGKINFVIASSK.G.ISK.E-VRAN.ELIRQVGKVLKGGGG.GR
 137 ........EKPIIAFA.--ESDKGVKVSARATY.R.LVE.RGVHLA.KALKRAAEAVGGVGG.GH
 138 ........-KAVMAFS.VNEDSGKVLCLAKVDK.S.LVS.NGLKAN.EWVNEVCTVLGGKGG.GK
 139 ........NKPVAVFS.--KGKTKAVGSIRSIE.-.---.-SIDVY.DKVSTMRDMF-LKWG.GH
 140 ........DKSIYLLA.--SDDTKVAHACLVSP.E.AMK.K-LTPQ.EWSQKVCHSIGGRSG.GK
 141 ........HRPVIAFA.-PAGDGILKGSGRSIA.G.L--.-HLHAL.ERLDTCHPGLMLKFG.GH
 142 ........------AI.VGSEKDGVRISARAKD.Y.LVK.KGLHLG.KLMEKVGPIIGGSGG.GH
 143 ........NKPVAIIA.--LQDGIGKGSLRTIG.-.---.-SFPLL.GVLRKCESFF-LSYG.GH
 144 ........EKPVIVFAdTDEDPNLIKGSARTTE.K.ALE.RGYHLG.EALRKAAEIIGGEGG.GH
 145 ........NKPVVIIA.--IQRGIGKGSARTIG.-.---.-SFPLL.GVLKKCSSLL-LSYG.GH
 146 ........---AYALI.EKPEEGVWKVSLRAKG.-.---.-NVNVG.KIAER------LGGG.GH
 147 ........--SAMLFT.VDNEAGKITCLCQVPQ.N.AAN.RGLKAS.EWVQQVSGLMDGKGG.GK
 148 ........DKPVVVVA.--LNNGIGKASCRSIL.-.---.-GIDFSaEIINAKSKDLIISGG.GH
 149 ........DKSIYLLA.GNDPEGRVAHGCYISN.A.ALA.KGIDGS.ALAKKVSSIIGGKAG.GK
 150 ........DKSIYLLA.GNDPEGRVAHGCYISN.A.ALA.KGIDGS.ALAKKVSSIIGGKAG.GK
 151 ........--AAMFLS.VDADSKKIFCLSSVPK.S.AVE.KGLKAN.EWVQHVSATLGGKGG.GK
 152 ........--PMIGLG.--ETADGLKVSLRCSR.L.LAF.DGIHFG.SIMRRVAEKVGGSGG.GH
 153 ........---FISLW.ITEKNGRYIVLSRVSD.D.LTK.RGVQAH.TLLAELLAPYGGRCG.GK
 154 ........--AAMFLS.VDADSKKIFCLSSVPK.S.AVE.KGLKAN.EWVQHVSATLGGKGG.GK
 155 ........------AI.VGSEKDGVRISARAKD.Y.LVK.QGLHLG.KIMEKVGPIIKGSGG.GH
 156 ........---FISLW.ITEKNGRYIVLSRVSD.D.LTK.RGVQAH.TLLAELLAPYGGRCG.GK
 157 ........---VIAFA.-SILDEKVNLVVGVTN.D.LTA.K-IKAG.ELVNLMAQQVGGKGG.GR
 158 ........----IIML.GNVAEGKVGLIAGVTN.D.LTN.K-VKAG.ELVNMVALQVGGKGG.GR
 159 ........--IWTTCY.FNEDIKKWIGSIRSRS.-.---.--IPIN.NFAQM------FGGG.GH
 160 ........--NAVILL.AAVNDGKVSLCAGVSK.P.LTG.K-VKAG.DLVKFAAEQVGGKGG.GR
 161 ........-RPTIVFA.-PADNGEVRGSGRSIP.N.LHL.R--DAL.DLVSKRHPDLILKFG.GH
 162 ........-RPTIVFA.-PADNGEVRGSGRSIP.N.LHL.R--DAL.DLVSKRHPDLILKFG.GH
 163 ........-RPTIVFA.-PADNGEVRGSGRSIP.N.LHL.R--DAL.DLVSKRHPDLILKFG.GH
 164 ........---AVIVL.GAVQNDKVNISAGVTK.D.LIE.KGLHAG.KLVKQAAEVCGGGGG.GR
 165 ........---TIIVL.ATVVEGKVSLIAGVSK.D.VTD.R-VKAG.ELIGMVAQQVGGKGG.GR
 166 ........----IVIL.FSKFENKVSLVVKVSE.N.LLG.K-YDAS.SIARNIAKELGGNGG.GR
 167 ........--NAVILL.AAVNDGKVSLCAGVSK.P.LTG.K-VKAG.DLVKFAAEQVGGKGG.GR
 168 ........---AVILL.IQVKDEKITLAAGVKD.-.---.VPLKAG.ALVKEAAQILGGNGG.GR
 169 ........NKPAFVFS.--QNEEHLKGSARSVG.-.---.-KIDIL.ALISKTNSIL-SNYG.GH
 170 ........----VAIF.LTKQDNIIKGSIRSNN.-.---.-KINSK.TLISIIPSHLVINSG.GH
 171 ........----PIFA.ITEDENGYKVSARCPK.L.LCFaEDVNLA.KAIKYASEKVNGSGG.GH
 172 ........---VAVLF.MEFPRGKIHVSMRSKD.-.---.-WFNVN.EVAFE------LGGG.GH
 173 ........NQDTLFIS.FNLDDNKIQYLLAINE.KfATT.NQINLN.KYIKELNTISNGKGG.GK
 174 ........-EKLLAIV.FKKENERITLACGVKN.-.---.VPIKAN.AWANEVAQILGGKGG.GR
 175 ........EPAVVALI.AEGESQTVPYAVAANP.A.AQD.LGIRAN.DLVKQLAVAVEGRGG.GK
 176 ........--IWFIVY.FDENTNTYKVSLRSNK.-.---.--YKVR.LVASQ------FNGG.GH
 177 ........---VIICI.--MADGHAVGSLRSAR.-.---.-GYHLF.SLLDPLADLF-SDYG.GH
 178 ........DKPLIVVN.--IKNEYAKVSARTNE.A.LAE.R-VDLA.EVMRLAAEKVGGRGG.GH
 179 ........--IWTTVY.FNESIKKWIGSIRSRN.-.---.--IPIN.NFAQM------FNGG.GH
 180 ........---TIIVL.ATVVEGKVSLIAGVSK.D.VTD.R-VKAG.ELIGMVAQQVGGKGG.GR
 181 ........---TIIVL.ATVVEGKVSLIAGVSK.D.VTD.R-VKAG.ELIGMVAQQVGGKGG.GR
 182 ........-ERLLAMV.FKKENERITLACGVKN.-.---.APIKAN.VWANEVAQILGGKGG.GR
 183 ........EKGAVGCL.MAKGEGKVFVVTFSGQ.-.---.-KYDAR.ELLREIGRVAKGSGG.GR
 184 ........-SAVVLAS.IPEEGKVSLVAAFSPQ.L.VKT.KQLKAG.QFIGAIAKICGGGGG.GR


             60        70             
             |         |             
   1 AMAAGLSLEE-DKFKLFQQRF--ge.......
   2 AMAAGLSLVE-DRFDEFRQRF--ad.......
   3 AMAAGLSIRE-EHFADFQHIFNQ.........
   4 PFAAGLSLPL-DKLPLFTEAVN-q........
   5 PMAAGMTLKA-EDVPDLRSRLNE.........
   6 AFAAGFSIPS-ERIPQLLHR---mel......
   7 DFAAGVIMKE-DKVEDFKKKFV-h........
   8 DFAAGIIINE-DQVEAFRKKFI-h........
   9 DFAAGLMIKE-DQVEGFRKKFI-h........
  10 AMAAGFTATA-SKLQELQDFLND.........
  11 RQACGLSVGK-NNIVSLFET---lenf.....
  12 DKAMGLTLPS-NRLEEFREKVNQ.........
  13 KYAAAFVLDEKNQFMKLVQIMDD.........
  14 KAAAGFTLHE-NLLEDFIKE---ley......
  15 RNASGGKIDG-------------fke16vee.
  16 KYASGAKIKT-NSYEEALKKLLE.........
  17 KNASGFRIKQ-GSLEIVKN----rmla.....
  18 RCAAGLRIE--GTVDELLPRF--va.......
  19 RLAAGYTTT--GSIDDAV-----aslra....
  20 IQASGAVLKSKRDI---------irvvqd...
  21 NNASGAIITNKKQISDVVSD---cvkkivy..
  22 AKASGCSITD-EVYELFVA----eafr.....
  23 QTAAAAKIP--------------lgi19vee.
  24 PQAGGARIP--------------lgi19vee.
  25 AHAAGAQIP--------------lgi19ite.
  26 SEAGGLNAP--------------ydk13ike.
  27 AGAAGANGK--ENLDEAIKFLV-ke.......
  28 KFACGAYIP--DNKREFIK----ylei.....
  29 ATACGAYIPS-EREREFLELLD-r........
  30 AIAAGIRVPK-ARFAEFRKLID-k........
  31 SVAAGATIPE-GREDEFLKLLD-r........
  32 DIAAGAMVPY-RDMESFLQLVDE.........
  33 RVAAGANITP-DKVEEFLKEVD-r........
  34 DVASGAVVSK-DKVQEFLKRVDE.........
  35 LTNAATQLSG-ISVSEALERLK-h........
  36 REAGAVKLEN-VSAERI------kelika...
  37 RDIAQGKVKDISKAKDVIE----siks.....
  38 KDVAQGAVQQLLDREEMLDVIF-r........
  39 ADLAQGGGKAPDKFPEAVKLLKE.........
  40 PELAQAGAGNPAALDAALNA---ard......
  41 PDMAQAGGTDAAALPAA------lasvkg...
  42 PDMAQAGGKQPEKLEEAL-----asved....
  43 PDMAMAGGSQLENVTQAIKVA--qd.......
  44 RDMAQAGGSEGGKADEALVA---lkd......
  45 PNLAQAGGRDASKLPEALATA--kq.......
  46 ASIAQAGGNDIINLTNINKKLW-s........
  47 EHLAQGKYE--GDVEEIKKKVIE.........
  48 DQSAQGSAPALPATEVLNETLWQ.........
  49 AISAQGSSAELPQIEFLNKTLR-q........
  50 DNLARGRVE--AKPEEIFDVAL-eklrs....
  51 GDTCQGVGDKPLSIDVAVEEAIE.........
  52 GNVFQGMGDKPAAIKDAVDD---les......
  53 PHLAQGAGPATDKVDEALEE---ara......
  54 GALAQGGGLDPRKAREALP----gllp.....
  55 ADLAQGSGKNPTGIDAALD----avrs.....
  56 DANAQLTGENVDKLDAAVELA--qk.......
  57 DVSAQATGKNVGCLQEALQL---ats......
  58 AESAQASGNNPNSLNEAIQIANE.........
  59 GDFASAGGKDIENLQAALNL---akn......
  60 GGLASGQGTDASQVQAALDM---ass......
  61 AMAAGLSLEE-DKFKLFQQRF--ge.......
  62 AMAAGLSLVE-DRFDEFRQRF--ad.......
  63 AMAAGLSIRE-EHFADFQHIFNQ.........
  64 PFAAGLSLPL-DKLPLFTEAVN-q........
  65 PMAAGMTLKA-EDVPDLRSRLNE.........
  66 AFAAGFSIPS-ERIPQLLHR---mel......
  67 DFAAGVIMKE-DKVEDFKKKFV-h........
  68 DFAAGIIINE-DQVEAFRKKFI-h........
  69 DFAAGLMIKE-DQVEGFRKKFI-h........
  70 AMAAGFTATA-SKLQELQDFLND.........
  71 RQACGLSVGK-NNIVSLFET---lenf.....
  72 DKAMGLTLPS-NRLEEFREKVNQ.........
  73 KYAAAFVLDEKNQFMKLVQIMDD.........
  74 KAAAGFTLHE-NLLEDFIKE---ley......
  75 RNASGGKIDG-------------fke16vee.
  76 KYASGAKIKT-NSYEEALKKLLE.........
  77 KNASGFRIKQ-GSLEIVKN----rmla.....
  78 RCAAGLRIE--GTVDELLPRF--va.......
  79 RLAAGYTTT--GSIDDAV-----aslra....
  80 IQASGAVLKSKRDI---------irvvqd...
  81 NNASGAIITNKKQISDVVSD---cvkkivy..
  82 AKASGCSITD-EVYELFVA----eafr.....
  83 QTAAAAKIP--------------lgi19vee.
  84 PQAGGARIP--------------lgi19vee.
  85 AHAAGAQIP--------------lgi19ite.
  86 SEAGGLNAP--------------ydk13ike.
  87 AGAAGANGK--ENLDEAIKFLV-ke.......
  88 KFACGAYIP--DNKREFIK----ylei.....
  89 ATACGAYIPS-EREREFLELLD-r........
  90 AIAAGIRVPK-ARFAEFRKLID-k........
  91 SVAAGATIPE-GREDEFLKLLD-r........
  92 DIAAGAMVPY-RDMESFLQLVDE.........
  93 RVAAGANITP-DKVEEFLKEVD-r........
  94 DVASGAVVSK-DKVQEFLKRVDE.........
  95 LTNAATQLSG-ISVSEALERLK-h........
  96 REAGAVKLEN-VSAERI------kelika...
  97 RDIAQGKVKDISKAKDVIE----siks.....
  98 KDVAQGAVQQLLDREEMLDVIF-r........
  99 ADLAQGGGKAPDKFPEAVKLLKE.........
 100 PELAQAGAGNPAALDAALNA---ard......
 101 PDMAQAGGTDAAALPAA------lasvkg...
 102 PDMAQAGGKQPEKLEEAL-----asved....
 103 PDMAMAGGSQLENVTQAIKVA--qd.......
 104 RDMAQAGGSEGGKADEALVA---lkd......
 105 PNLAQAGGRDASKLPEALATA--kq.......
 106 ASIAQAGGNDIINLTNINKKLW-s........
 107 EHLAQGKYE--GDVEEIKKKVIE.........
 108 DQSAQGSAPALPATEVLNETLWQ.........
 109 AISAQGSSAELPQIEFLNKTLR-q........
 110 DNLARGRVE--AKPEEIFDVAL-eklrs....
 111 GDTCQGVGDKPLSIDVAVEEAIE.........
 112 GNVFQGMGDKPAAIKDAVDD---les......
 113 PHLAQGAGPATDKVDEALEE---ara......
 114 GALAQGGGLDPRKAREALP----gllp.....
 115 ADLAQGSGKNPTGIDAALD----avrs.....
 116 DANAQLTGENVDKLDAAVELA--qk.......
 117 DVSAQATGKNVGCLQEALQL---ats......
 118 AESAQASGNNPNSLNEAIQIANE.........
 119 GDFASAGGKDIENLQAALNL---akn......
 120 GGLASGQGTDASQVQAALDM---ass......
 121 DIAAGAMVPY-RDMESFLQLVDE.........
 122 PMAAGMTLKA-EDVPDLRSRLNE.........
 123 AMAAGLSIRE-EHFADFQHIFNQ.........
 124 AMAAGLTIEE-QNFERFCRLFDQ.........
 125 DQSAQGSAPALPATEVLNETLWQ.........
 126 AESAQASGNNPNSLNEAIQIANE.........
 127 DFAAGIIINE-DQVEAFRKKFIH.........
 128 DFAAGLMIKE-EQIEGFRKKFIH.........
 129 AIAAGIRVPK-ARLAEFRKLID-.........
 130 DFAAGIIINE-DQVEAFRKKFIH.........
 131 ADLAQGGGKAPDKFPEAVKLLKE.........
 132 AMAAGLSLEE-DKFKLFQQRF--.........
 133 DVASGAVVSK-DKVQEFLKRVDE.........
 134 AMAAGLSLEE-DKFKLFQQRF--.........
 135 AVSAQGSSKELPQIEVLNTIL--.........
 136 EDLAQGGGKAPDKFDESVKLLKE.........
 137 SVAAGATIPE-GREDEFLKLLD-.........
 138 DANAQLTGENVDKLDAAVEL---.........
 139 DKAMGLTLPS-NRLEEFREKVNQ.........
 140 GDTCQGVGDKPLSIDVAVEEAIE.........
 141 AMAAGLSLVE-DRFDEFRQRF--.........
 142 PGAAGANGK--ENLDEAIKFL--.........
 143 DFAAGLMIKE-DQVEGFRKKFI-.........
 144 AIAAGIRVPK-ARFAEFRKLID-.........
 145 DFAAGVIMKE-DKVEDFKKKFV-.........
 146 KYASGAKIKT-NSYEEALKKLLE.........
 147 DVSAQATGKNVGCLQEALQL---.........
 148 AMAAGFTATA-SKLQELQDFLND.........
 149 GNVFQGMGDKPAAIKDAVDDL--.........
 150 GNVFQGMGDKPAAIKDAVDDL--.........
 151 PESAQASGTNYEKVDEIVQL---.........
 152 ATACGAYIPS-EREREFLELLD-.........
 153 AISAQGSSAELPQIEFLNKTLR-.........
 154 PESAQASGTNYEKVDEIVQL---.........
 155 AGAAGANGK--ENLDEAIKFL--.........
 156 AISAQGSSAELPQIEFLNKTLR-.........
 157 PDMAMAGGSQLENVTQAIKVA--.........
 158 PDMAQAGGTDAHALPSALESV--.........
 159 KYAAAFVLDDKRQFMKLVEIMDD.........
 160 PDLAQAGGTDADKLPAVLDSV--.........
 161 AMAAGLSILE-HNIPAFQTTF--.........
 162 AMAAGLSILE-HNIPAFQTTF--.........
 163 AMAAGLSILE-HNIPAFQTAF--.........
 164 PDMAQAGGKQPEKLEEALA----.........
 165 PDMAQAGGTDAAALPAA------.........
 166 KNFAQAGGRHPERIKDVLERLE-.........
 167 PDLAQAGGTDAGKLPEML-----.........
 168 DDFATAGGKDLSKINEALK----.........
 169 KGAAGISLNS-ENFEQFKNKI--.........
 170 KAAAGFTLHE-NLLEDFIKEL--.........
 171 KFACGAYIP--DNKREFIKY---.........
 172 PRAAGVTFEG-KKIEEVIPRV--.........
 173 PYFVQGGTSEQEKLDELLTVV--.........
 174 DDFASAGGKDIENLQAALNL---.........
 175 ADLAQGSGKNPTGIDAALDA---.........
 176 DLAAGCSLTNIDQLENLLSAL--.........
 177 AFAAGFSIPS-ERIPQLLHR---.........
 178 RVAAGANITP-DKVEEFLKEVD-.........
 179 KYAAAFVLDEKNQFMKLVQIMDD.........
 180 PDMAQAGGTDAAALPAA------.........
 181 PDMAQAGGTDAAALPAA------.........
 182 GDFASAGGKDIENLQAALNL---.........
 183 KDVAQGAVQQLLDREEMLDVIF-.........
 184 PNLAQAGGRDASKLPEALAT---.........