Citations (SAM, SAM-T99, HMMs)
10 20 30 40 50
| | | | |
1 .....AVLDGRPIIIRHHA--DTDGYCGGIALEKAILPIid6aiD.VDAIWHFFKR--RPSKAPF
2 .....AVYDGRSILVRHHA--DADGICAGVAIEKAVLPLlr6npS.TDAEWHYFKR--APSKAPF
3 .....AIFEGRPIILRHHA--DTDGYTAGVALETAIVPLie6apD.PDARWHLFKR--RPSRAPF
4 .....AIYESRPVIIRHHW--DADGTCGGVALEKALTDLve6hsD.SEAKYYLVKR--RVSRAPF
5 rs...--YAGGGVTVVHHN--DADGLCSGALLKKLCEYC.....G.FEAELICIEK---------
6 i....-LNHYGYIRVITHH--DTDGLSSGGILAKMLMRT.....N.KLFHLTVVEHLSKEVIEKL
7 .....HLERGNIIRIISHN--DADGLSAAGVVARAISSM.....N.GQFHISILSRLKKEF----
8 .....HIELGHTIRIISHR--DADGITSAAILAKALARE.....G.AKFHISIVKQ---------
9 l....-VARHDFIRIYTHH--DADGISAGAIIAKALLKA.....G.KAFHITFLKGLNEPFEYE-
10 r....-ILKNEEVLVVTHI--DADGITAGTIAHTSLLRA.....G.VESGIRFVKQLDESEIEAI
11 qn...--NKNNKILIVTHI--DTDGLTSRAILQKLAERL.....N.LDADFMFLKQ---------
12 m....-VESSETVTVYSHT--DCDGITAATVLSKVLERL.....D.MDHEVRIININEVPEVEL-
13 mismn--------LIIHHW--DTDGITSAALLIKALELD.....E.FRNMSPPIGE---------
14 a....-MRTNTEILVVGDY--DADGVISSAIMAKFFESL.....NyKHVRIAIPNRFMDGYGISK
15 .....AIVNSQQICIFADY--DVDGATSAALLKHFLRDL.....N.IICDIYVPDRIYEGYGPT-
16 .....AISQQEKIMIYGDY--DADGVTSTSVMLHTLQKL.....S.AQVDFYIPDRFKEGYGPN-
17 a....-FREGTRIIVVGDF--DADGATSTALSVLAMRSL.....GcSNIDYLVPNRFEDGYGLS-
18 .....ALADNRRIVIVGDF--DADRATSTALTVLALRSM.....AaREVQYLVPNRFEDGYGLS-
19 ay...--QPQQKIVIVGDF--DADGATSTALSVLALRQL.....GfSDVDYLVPNRFEQGYGLS-
20 .....AIKNNENILIFGDK--DADGITATIIMYETLKDF.....G.LNVSYKIPSN-GEFYGLS-
21 a....-RDRKEHVMIYGDS--DVDGMTGVALLVEFLRDI.....D.VHVSYFFLGAILKQHGET-
22 .....AKERNEHVMVYGDS--DVDGMTGVALLVEFLRSI.....D.MKVSYCFLGALLKHYGEP-
23 a....-KANNEHVMIYGDG--DVDGITGVTLIVEFLQIL.....G.VKTSYCCSGTLFKQHGET-
24 .....AVLKKKRIIIYGDY--DVDGITGTAILYRVLKLL.....G.AKVYPVLPNR-QTGYGLN-
25 .....AMAQKEKVTIWGDF--DADGITSTAVLWEGLGQFfpq..D.SQLTYTIPNRLRESHGLNR
26 .....AHERKEKVLIFGDR--DADGISATTLLFEALCAF.....G.LTVCWRVPVA-DEPYGLS-
27 .....HLNNKNKLFVQVDS--DVDGYTSSSIIINYIKKI.....C.PKANIHYRIQDGKEHGIF-
28 .....EAKQHRPIVFYTDN--DCDGMLAGSVLMSMCYRL.....GiKDFFFFSPLRNAHGYGFTD
29 mv7vv----------ILSEGADLDSLSAAYGVLK----L.....Y.PDAYLLKPKHLSKKAGEVF
30 i....-VTESSNVIIMGHKFPDMDSIGAAIGILKVAQAN.....N.KDGFIVIDPNQIGSSVQRL
31 kl...--KTFDNFSLYVHVNPDFDAFGAAFAFKAFLAVY.....F.PHKKAYVMGS--HNIKADG
32 ti...--SLYDTIILHRHVRPDPDAYGSQCGLTEILRET.....Y.PEKNIFAVGTPEPSLSFL-
33 .....AIKQFDKIVIFHHVRPDGDCLGAQQGLFHLIKAN.....F.KNKEVKCVGN--NNNLFSF
34 .....AIQAHDKIVIFHHIRPDGDCLGAQHGLARLIQTN.....F.PHKQVFCVGD--PKHNFPW
35 lk...--NVKGSILILTHENPDGDSLGSGLALYKFLKKK.....G.KEVYIGSKDGVPHFLDFL-
36 .....FIKKYNNFVIIGHKDPDFDCIGSSLALSSFLSRI.....G.KNSILLNEGPFIRKEIVPF
37 f....-IDAHRAFAVVGHEKPDGDCVGSSLALASFLRRI.....G.KEVELLSAGPFKRREIAAY
38 llsaa-----ARVGVVCHVHPDADTIGAGLALALVLDGC.....G.KRVEVSFAAPATLPESLRS
39 gh...---QGQRLILVIQDFPDPDALSSAWAFQLIAAQY.....E.IQCDIVYAGTLSHQENIAL
40 ee...--EKKAPLLILTHINPDPDAIASAMALKTLAERW.....G.VDSDIAYGGNIGYDENKAM
41 e....-SLRGKRLGIFTHDNPDPDSMSSAYALREIAKQF.....D.VIADILYYGEILHQKNRAM
42 i....-KEKTDTLLIVMHDNPDPDCMASASALAVIAQSI.....G.LKTQIVYGGDITHHQNRAM
43 l....--NRDEGIILLCHHNADPDSLGSAIAFSNFLLSK.....G.FSRIRIGVAQSIASYSRRL
44 e....-YLKRDEVLFLCHHNADPDAVGSCVALKYLASQL.....N.PNGKFRISADSVSKLSRNI
45 .....EIAIHGSFLLLGHEHPDEDCIASLVAFALLLTRC.....N.KRVEICCQGPIRVQISFL-
46 q....-------VYHLSHI--DLDGYACQLVSKQFFKNI.....Q.-----CYNANYGREVSARI
47 myh..---------LYSHN--DLDGVGCGIVAKLA---F.....G.KDVEIRYNSV--NGLNAQ-
48 .....AVLDGRPIIIRHHA--DTDGYCGGIALEKAILPIid6aiD.VDAIWHFFKR--RPSKAPF
49 .....AVYDGRSILVRHHA--DADGICAGVAIEKAVLPLlr6npS.TDAEWHYFKR--APSKAPF
50 .....AIFEGRPIILRHHA--DTDGYTAGVALETAIVPLie6apD.PDARWHLFKR--RPSRAPF
51 .....AIYESRPVIIRHHW--DADGTCGGVALEKALTDLve6hsD.SEAKYYLVKR--RVSRAPF
52 rs...--YAGGGVTVVHHN--DADGLCSGALLKKLCEYC.....G.FEAELICIEK---------
53 i....-LNHYGYIRVITHH--DTDGLSSGGILAKMLMRT.....N.KLFHLTVVEHLSKEVIEKL
54 .....HLERGNIIRIISHN--DADGLSAAGVVARAISSM.....N.GQFHISILSRLKKEF----
55 .....HIELGHTIRIISHR--DADGITSAAILAKALARE.....G.AKFHISIVKQ---------
56 l....-VARHDFIRIYTHH--DADGISAGAIIAKALLKA.....G.KAFHITFLKGLNEPFEYE-
57 r....-ILKNEEVLVVTHI--DADGITAGTIAHTSLLRA.....G.VESGIRFVKQLDESEIEAI
58 qn...--NKNNKILIVTHI--DTDGLTSRAILQKLAERL.....N.LDADFMFLKQ---------
59 m....-VESSETVTVYSHT--DCDGITAATVLSKVLERL.....D.MDHEVRIININEVPEVEL-
60 mismn--------LIIHHW--DTDGITSAALLIKALELD.....E.FRNMSPPIGE---------
61 a....-MRTNTEILVVGDY--DADGVISSAIMAKFFESL.....NyKHVRIAIPNRFMDGYGISK
62 .....AIVNSQQICIFADY--DVDGATSAALLKHFLRDL.....N.IICDIYVPDRIYEGYGPT-
63 .....AISQQEKIMIYGDY--DADGVTSTSVMLHTLQKL.....S.AQVDFYIPDRFKEGYGPN-
64 a....-FREGTRIIVVGDF--DADGATSTALSVLAMRSL.....GcSNIDYLVPNRFEDGYGLS-
65 .....ALADNRRIVIVGDF--DADRATSTALTVLALRSM.....AaREVQYLVPNRFEDGYGLS-
66 ay...--QPQQKIVIVGDF--DADGATSTALSVLALRQL.....GfSDVDYLVPNRFEQGYGLS-
67 .....AIKNNENILIFGDK--DADGITATIIMYETLKDF.....G.LNVSYKIPSN-GEFYGLS-
68 a....-RDRKEHVMIYGDS--DVDGMTGVALLVEFLRDI.....D.VHVSYFFLGAILKQHGET-
69 .....AKERNEHVMVYGDS--DVDGMTGVALLVEFLRSI.....D.MKVSYCFLGALLKHYGEP-
70 a....-KANNEHVMIYGDG--DVDGITGVTLIVEFLQIL.....G.VKTSYCCSGTLFKQHGET-
71 .....AVLKKKRIIIYGDY--DVDGITGTAILYRVLKLL.....G.AKVYPVLPNR-QTGYGLN-
72 .....AMAQKEKVTIWGDF--DADGITSTAVLWEGLGQFfpq..D.SQLTYTIPNRLRESHGLNR
73 .....AHERKEKVLIFGDR--DADGISATTLLFEALCAF.....G.LTVCWRVPVA-DEPYGLS-
74 .....HLNNKNKLFVQVDS--DVDGYTSSSIIINYIKKI.....C.PKANIHYRIQDGKEHGIF-
75 .....EAKQHRPIVFYTDN--DCDGMLAGSVLMSMCYRL.....GiKDFFFFSPLRNAHGYGFTD
76 mv7vv----------ILSEGADLDSLSAAYGVLK----L.....Y.PDAYLLKPKHLSKKAGEVF
77 i....-VTESSNVIIMGHKFPDMDSIGAAIGILKVAQAN.....N.KDGFIVIDPNQIGSSVQRL
78 kl...--KTFDNFSLYVHVNPDFDAFGAAFAFKAFLAVY.....F.PHKKAYVMGS--HNIKADG
79 ti...--SLYDTIILHRHVRPDPDAYGSQCGLTEILRET.....Y.PEKNIFAVGTPEPSLSFL-
80 .....AIKQFDKIVIFHHVRPDGDCLGAQQGLFHLIKAN.....F.KNKEVKCVGN--NNNLFSF
81 .....AIQAHDKIVIFHHIRPDGDCLGAQHGLARLIQTN.....F.PHKQVFCVGD--PKHNFPW
82 lk...--NVKGSILILTHENPDGDSLGSGLALYKFLKKK.....G.KEVYIGSKDGVPHFLDFL-
83 .....FIKKYNNFVIIGHKDPDFDCIGSSLALSSFLSRI.....G.KNSILLNEGPFIRKEIVPF
84 f....-IDAHRAFAVVGHEKPDGDCVGSSLALASFLRRI.....G.KEVELLSAGPFKRREIAAY
85 llsaa-----ARVGVVCHVHPDADTIGAGLALALVLDGC.....G.KRVEVSFAAPATLPESLRS
86 gh...---QGQRLILVIQDFPDPDALSSAWAFQLIAAQY.....E.IQCDIVYAGTLSHQENIAL
87 ee...--EKKAPLLILTHINPDPDAIASAMALKTLAERW.....G.VDSDIAYGGNIGYDENKAM
88 e....-SLRGKRLGIFTHDNPDPDSMSSAYALREIAKQF.....D.VIADILYYGEILHQKNRAM
89 i....-KEKTDTLLIVMHDNPDPDCMASASALAVIAQSI.....G.LKTQIVYGGDITHHQNRAM
90 l....--NRDEGIILLCHHNADPDSLGSAIAFSNFLLSK.....G.FSRIRIGVAQSIASYSRRL
91 e....-YLKRDEVLFLCHHNADPDAVGSCVALKYLASQL.....N.PNGKFRISADSVSKLSRNI
92 .....EIAIHGSFLLLGHEHPDEDCIASLVAFALLLTRC.....N.KRVEICCQGPIRVQISFL-
93 q....-------VYHLSHI--DLDGYACQLVSKQFFKNI.....Q.-----CYNANYGREVSARI
94 myh..---------LYSHN--DLDGVGCGIVAKLA---F.....G.KDVEIRYNSV--NGLNAQ-
95 .....AKERNEHVMVYGDS--DVDGMTGVALLVEFLRSI.....D.MKVSYCFLGALLKHYGEP-
96 .....AISQQEKIMIYGDY--DADGVTSTSVMLHTLQKL.....S.AQVDFYIPDRFKEGYGPN-
97 .....-KANNEHVMIYGDG--DVDGITGVTLIVEFLQIL.....G.VKTSYCCSGTLFKQHGET-
98 .....AVGRKEKILIVADY--DADGATACAVGMSGLAAM.....G.AKVDFLVPNRFEHGYGLT-
99 .....-FREGTRIIVVGDF--DADGATSTALSVLAMRSL.....GcSNIDYLVPNRFEDGYGLS-
100 .....AIAEQKRIIVVGDF--DADGATSSALSVLALRML.....GsRNVDYLVPNRFEDGYGLS-
101 .....-FREGTRIIVVGDF--DADGATSTALSVLAMRSL.....GcSNIDYLVPNRFEDGYGLS-
102 .....--QPQQKIVIVGDF--DADGATSTALSVLALRQL.....GfSDVDYLVPNRFEQGYGLS-
103 .....ALADNRRIVIVGDF--DADRATSTALTVLALRSM.....AaREVQYLVPNRFEDGYGLS-
104 .....-RDRKEHVMIYGDS--DVDGMTGVALLVEFLRDI.....D.VHVSYFFLGAILKQHGET-
105 .....AIVNSQQICIFADY--DVDGATSAALLKHFLRDL.....N.IICDIYVPDRIYEGYGPT-
106 .....AVLDGRPIIIRHHA--DTDGYCGGIALEKAILPIid6aiD.VDAIWHFFKR--RPSKAPF
107 .....AVERQEKILIVADY--DADGATACAVGLDGLAAM.....G.AKVDFLVPNRFEHGYGLT-
108 .....AIQAHDKIVIFHHIRPDGDCLGAQHGLARLIQTN.....F.PHKQVFCVGD--PKHNFPW
109 .....-RSKNELVLIHGDY--DVDGITSTVMLKEFLEEN.....G.WRVDVYIPHRIEEGYGIQ-
110 .....FIKKYNNFVIIGHKDPDFDCIGSSLALSSFLSRI.....G.KNSILLNEGPFIRKEIVPF
111 .....AVYDGRSILVRHHA--DADGICAGVAIEKAVLPLlr6npS.TDAEWHYFKR--APSKAPF
112 .....--ENNEHVMIYGDG--DVDGITGVTLLVEFLQML.....G.VKTSYCCSGTLFKQHGEI-
113 .....AIYESRPVIIRHHW--DADGTCGGVALEKALTDLve6hsD.SEAKYYLVKR--RVSRAPF
114 .....AIAAQRRILVVGDF--DCDGATACAVGVRGLRML.....GaLDVHHAVPNRMVHGYGLS-
115 .....AIKQFDKIVIFHHVRPDGDCLGAQQGLFHLIKAN.....F.KNKEVKCVGN--NNNLFSF
116 .....--NKNNKILIVTHI--DTDGLTSRAILQKLAERL.....N.LDADFMFLKQ---------
117 .....AVERKEKILIVADY--DADGATACAVGLDGLAAM.....G.AKVDFLVPNRFEHGYGLT-
118 .....-IKANGRILVVGDF--DCDGATACAVAVRGLRLL.....GaRNVMHAVPNRMVHGYGLS-
119 .....AIKNNENILIFGDK--DADGITATIIMYETLKDF.....G.LNVSYKIPSN-GEFYGLS-
120 .....AVLKKKRIIIYGDY--DVDGITGTAILYRVLKLL.....G.AKVYPVLPNR-QTGYGLN-
121 .....AIKNNENILIFGDK--DADGITATIIMYETLKDF.....G.LNVSYKIPSN-GEFYGLS-
122 .....AVEKNEKVAIVGDY--DVDGIISCVIMAEFFDDI.....G.FDYIIRIPNRFKDGYGLN-
123 .....---LYDTIILHRHVRPDPDAYGSQCGLTEILRET.....Y.PEKNIFAVGTPEPSLSFL-
124 .....------RVGVVCHVHPDADTIGAGLALALVLDGC.....G.KRVEVSFAAPATLPESLR-
125 .....AIKNNENILIFGDK--DADGIXATIIMYETLKDF.....G.LNVSYXIPSN-GEFYGLS-
126 .....---QGQRLILVIQDFPDPDALSSAWAFQLIAAQY.....E.IQCDIVYAGTLSHQENIAL
127 .....-VKQFDKFSLFVHVNPDFDAFGSAFAFKTFLNTF.....F.SEKKAYVMGS--YNINADG
128 .....--KTFDNFSLYVHVNPDFDAFGAAFAFKAFLAVY.....F.PHKKAYVMGS--HNIKADG
129 .....AIFEGRPIIIRHHA--DTDGYTAGVALETAIVPLie6apD.PDARWHLFKR--RPSRAPF
130 .....AIFEGRPIILRHHA--DTDGYTAGVALETAIVPLie6apD.PDARWHLFKR--RPSRAPF
131 .....-KEKTDTLLIVMHDNPDPDCMASASALAVIAQSI.....G.LKTQIVYGGDITHHQNRAM
132 .....EIAIHGSFLLLGHEHPDEDCIASLVAFALLLTRC.....N.KRVEICCQGPIRVQISFL-
133 .....HLNNKNKLFVQVDS--DVDGYTSSSIIINYIKKI.....C.PKANIHYRIQDGKEHGIF-
134 .....AVREGKRIRIHGDY--DADGVSATATLVLGLRAI.....G.ANVHGFIPHRLNEGYGIH-
135 .....-IELGHTIRIISHR--DADGITSAAIVAKALARE.....G.ADFHVSIVKQ---------
136 .....-IELGHTIRIISHR--DADGITSAAILAKALARE.....G.AKFHISIVKQ---------
137 .....-VTESSNVIIMGHKFPDMDSIGAAIGILKVAQAN.....N.KDGFIVIDPNQIGSSVQRL
138 .....--NVKGSILILTHENPDGDSLGSGLALYKFLKKK.....G.KEVYIGSKDGVPHFLDFL-
139 .....-KERTDSLLIVMHDNPDPDSMASASALAVIAQSV.....G.LRPQIVYGGDITHHQNRAM
140 .....-IDAHRAFAVVGHEKPDGDCVGSSLALASFLRRI.....G.KEVELLSAGPFKRREIAA-
141 .....HLERGNIIRIISHN--DADGLSAAGVVARAISSM.....N.GQFHISILSRLK-------
142 .....-VESSETVTVYSHT--DCDGITAATVLSKVLERL.....D.MDHEVRIININEVPEVEL-
143 .....EVKRHRPIIFYTDN--DCDGMLAGSVLMSMCYRL.....GiKDFFFFSPLRNAHGYGFTD
144 .....AMAQKEKVTIWGDF--DADGITSTAVLWEGLGQFfpq..D.SQLTYTIPNRLRESHGLN-
145 .....-VARHDFIRIYTHH--DADGISAGAIIAKALLKA.....G.KAFHITFLKGLNEPFEYE-
146 .....--YAGGGVTVVHHN--DADGLCSGALLKKLCEYC.....G.FEAELICIEK---------
147 .....------KILVFGHQNPDSDAIGSSMAYAYLKRQL.....G.VDAQAVALGNPNEETAFV-
148 .....-YLKRDEVLFLCHHNADPDAVGSCVALKYLASQL.....N.PNGKFRISADSVSKLSRN-
149 .....-AKQHRPIVFYTDN--DCDGMLAGSVLMSMCYRL.....GiKDFFFFSPLRNAHGYGFTD
150 .....-AKQHRPIVFYTDN--DCDGMLAGSVLMSMCYRL.....GiKDFFFFSPLRNAHGYGFTD
151 .....-MRTNTEILVVGDY--DADGVISSAIMAKFFESL.....NyKHVRIAIPNRFMDGYGISK
152 .....AHERKEKVLIFGDR--DADGISATTLLFEALCAF.....G.LTVCWRVPVA-DEPYGLS-
153 .....-LSQHDRILVVGHIMPDGDCVSSVLSLTLGLEKL.....G.KEVKAAVDYK---------
154 .....--AHPGPIVVLSHENPDGDALGSVLGLSRALRTL.....G.K----TVLAPMTVPHYLS-
155 .....-----EKILIFGHQNPDTDTICSAIAYADLKNKL.....G.FNAEPVRLGQVNGETQYA-
156 .....------KILVFGHQNPDSDAIGSSYAFAYLAREAy....G.LDTEAVALGEPNEETAFV-
157 .....--LRGKRLGIFTHDNPDPDSMSSAYALREIAKQF.....D.VIADILYYGEILHQKNRAM
158 .....--EKKAPLLILTHINPDPDAIASAMALKTLAERW.....G.VDSDIAYGGNIGYDENKAM
159 .....-LNRDEGIILLCHHNADPDSLGSAIAFSNFLLSK.....G.FSRIRIGVAQSIASYSRRL
160 .....-------ILVVGHKNPDSDSICSALVAAELLKAR.....G.LEAKAVRQGEINRETQHI-
161 .....-ILKNEEVLVVTHI--DADGITAGTIAHTSLLRA.....G.VESGIRFVKQLDESEIEAI
162 .....----FNKITIFVHTNPDCDALGSAFALARILKLNtf...G.TRVKIVGVNALNPNDFKNF
163 .....--------LIIHHW--DTDGITSAALLIKALELD.....E.FRNMSPPIGE---------
164 .....---------ITTHRSPDFDAFASCVAAKKLLD--.....-.-DHIIVLPSNPARNLSDFL
165 .....---EGEKSAVITHRNADPDAVGAALVVREVLRAL.....R.MNPCLYSPEGISRQSKRL-
166 .....-LNHYGYIRVITHH--DTDGLSSGGILAKMLMRT.....N.KLFHLTVVEHLSKEVIEKL
167 .....-------VYVVGHKNPDTDSVCSAIAFAYLWNKWk12kiE.AEAKPVIQGDVNPETKYVL
168 .....AMRANTEILVVGDY--DADGVISSAIMAKFFKSL.....NyKHVRVAIPNRFMDGYGISK
169 .....-LKRDEGIILLCHHNADPDSLGSAIAFSNFLLDR.....G.LRNVRIGVAQSIASYSRRL
170 .....-------VYHLSHI--DLDGYACQLVSKQFFKNI.....Q.-----CYNANYGREVSARI
171 .....---------LYSHN--DLDGVGCGIVAKLA---F.....G.KDVEIRYNSV--NGLNAQ-
172 .....-------VYHLSHI--DLDGYACQLVSKQFFKNI.....Q.-----CYNANYGREVSARI
173 .....--------LIIHHW--DTDGITSAALLMKKLG--.....-.----------------EDF
174 .....----------------------------------.....-.-------------------
175 .....---------VFGHLNPDTDAISAAMVYARLLTRQ.....G.TEAQAYRLGEPNFETAYVL
176 .....---------VVGHKNPDTDSIASAIVLAYFL---.....-.-DCYPARLGDINPETEFVL
177 .....----------------------------------.....-.-------------------
178 .....---------------ADLDSLSAAYGVLKL----.....Y.PDAYLLKPKHLSKKAGEVF
60 70 80 90
| | | |
1 YEL.....EDVT.....KDLVFSIEDAL...KFGQKLPLI.VLIDN...GSTD....E.....DI
2 YEL.....EDVV.....KDLSYALEDLE...RHGQKLPLL.VLLDN...GSTE....E.....DI
3 YEL.....EDVL.....KDIIFMMEDHM...RFGDELPLV.VIVDN...GGTT....E.....DI
4 YEL.....EDVV.....RDLDESLEDAE...RHGDKIPLV.VLVDN...GSGL....E.....DV
5 ---.....----.....---VYPAVVEK...IHSSRDGMI.IYTDL...GG--....L.....AA
6 AKE.....NEV-.....-----------...----NKPLF.IFADM...GS--....-.....--
7 ---.....----.....--------IKK...LSGEKYSLF.FFCDM...GS--....-.....--
8 ---.....----.....---VSEELVRQ...LKDEEYKII.IFSDL...GSGS....L.....SL
9 ---.....----.....-----------...----QGELL.LFADM...GS--....-.....--
10 KD-.....----.....-----------...----ENTFV.WFTDI...GS--....-.....--
11 ---.....----.....---ITIETIND...IPFKDYDLI.IFADL...GSGQlkmiK.....EK
12 ---.....----.....-----------...----SSDLT.IFSDL...GS--....-.....-G
13 ---.....----.....---FRFDDRIR...KAIEHAERV.YILDL...NLPY....D.....VE
14 KFL.....EKH-.....-----------...----HAPLI.ITVDN...GI--....N.....AF
15 ---.....----.....-----PLAMQK...IKGNGTELL.ITVDC...GA--....M.....AH
16 ---.....----.....-----EQAFRS...IKERGFSLI.ITVDT...GI--....A.....AV
17 ---.....----.....-----PEVVDQ...AHARGAQLI.VTVDN...GI--....S.....SH
18 ---.....----.....-----PEVVAQ...APAKGAELI.VTVDN...GI--....S.....SH
19 ---.....----.....-----IPVAEM...AIEKGVQLL.MTVDN...GV--....S.....SF
20 ---.....----.....-----NELINT...ALEKKISLI.ITVDN...GI--....S.....SI
21 ---.....----.....-----STLIAK...LKEEGITLL.ITVDC...GI--....T.....AG
22 ---.....----.....-----SSLIAK...MKEEKVTLL.ITVDC...GI--....T.....AG
23 ---.....----.....-----ASLISQ...MLQDGISLL.ITVDC...GI--....T.....AG
24 ---.....----.....------KELMS...IFEKYGDFL.ITVDN...GT--....-.....--
25 PGL.....ERL-.....-----------...-ATQGTKLI.VTCDT...GS--....T.....NL
26 ---.....----.....-----CNAVDE...HAAAGGTLI.VTVDC...GI--....S.....NR
27 ---.....----.....---------ID...TIPDDVDLV.IIPDA...GS--....S.....QF
28 LAL.....NDLLsq9pkTNQLVRLDCIK...NQFQKNPLL.FSADL...GADLa...A.....NT
29 KKY.....RDK-.....------FRVIE...DLPDCFE-L.VLVDT...HF--....-.....--
30 IGE.....IKKY.....EELWSRFITPEeamEISNDDTLL.VIVDT...HK--....P.....SL
31 KDL.....FPF-.....-----EAAPID...DAFVKNSLA.IIFDT...S---....N.....QE
32 ---.....----.....----YSLDEVD...NETYEGALV.IVCDT...A---....N.....QE
33 INM.....TF--.....------TNQID...ESFLKEALA.IVVDA...NYKN....R.....IE
34 LEM.....VFTP.....KEQITPELM--...----QQALA.VIVDA...NYKE....R.....IE
35 ---.....----.....---PGVEDVIN...PDGKFYDVG.IVVDA...SG--....-.....--
36 KD-.....----.....---KFLSEWPN...IEISEYS-V.IILDC...SI-L....D.....RI
37 ATL.....FR--.....-----PSLSAQ...IRPSDQTAV.IVVDC...SE-L....S.....RV
38 LPG.....CHL-.....------LVRPE...VMRRDVDLV.VTVDI...PS-V....D.....RL
39 VKL.....TGLP.....AKRWGPQMLKD...IDLSDYQGC.VLVDS...QGTN....S.....QL
40 INL.....LGI-.....----KLLNVED...IDLDNYCVI.AVIDT...ST--....-.....--
41 VNL.....LEI-.....----PMIRAPE...VDLSHYDAF.AIVDS...SG--....-.....--
42 VNV.....LGME.....FRKVSR---GS...YEIKRHKAI.AIVDA...QP--....N.....GN
43 VAL.....SRVP.....IEKDPVI----...----KENVI.FIFDT...SS--....-.....-I
44 LNE.....IG--.....-----ERVDIE...IYPKLPETV.FIVDT...AS--....I.....NQ
45 --I.....DICL.....YNGIAVHLDTQ...TVPRMPDAL.VILDTpnpGMIY....A.....PP
46 YEI.....LNA-.....---------IA...QSKESEFLI.LVSDL...NLNL....Nea6lqDK
47 ---.....----.....---VQYFLEKA...KESNRQDAL.FITDL...AVNE....E.....NE
48 YEL.....EDVT.....KDLVFSIEDAL...KFGQKLPLI.VLIDN...GSTD....E.....DI
49 YEL.....EDVV.....KDLSYALEDLE...RHGQKLPLL.VLLDN...GSTE....E.....DI
50 YEL.....EDVL.....KDIIFMMEDHM...RFGDELPLV.VIVDN...GGTT....E.....DI
51 YEL.....EDVV.....RDLDESLEDAE...RHGDKIPLV.VLVDN...GSGL....E.....DV
52 ---.....----.....---VYPAVVEK...IHSSRDGMI.IYTDL...GG--....L.....AA
53 AKE.....NEV-.....-----------...----NKPLF.IFADM...GS--....-.....--
54 ---.....----.....--------IKK...LSGEKYSLF.FFCDM...GS--....-.....--
55 ---.....----.....---VSEELVRQ...LKDEEYKII.IFSDL...GSGS....L.....SL
56 ---.....----.....-----------...----QGELL.LFADM...GS--....-.....--
57 KD-.....----.....-----------...----ENTFV.WFTDI...GS--....-.....--
58 ---.....----.....---ITIETIND...IPFKDYDLI.IFADL...GSGQlkmiK.....EK
59 ---.....----.....-----------...----SSDLT.IFSDL...GS--....-.....-G
60 ---.....----.....---FRFDDRIR...KAIEHAERV.YILDL...NLPY....D.....VE
61 KFL.....EKH-.....-----------...----HAPLI.ITVDN...GI--....N.....AF
62 ---.....----.....-----PLAMQK...IKGNGTELL.ITVDC...GA--....M.....AH
63 ---.....----.....-----EQAFRS...IKERGFSLI.ITVDT...GI--....A.....AV
64 ---.....----.....-----PEVVDQ...AHARGAQLI.VTVDN...GI--....S.....SH
65 ---.....----.....-----PEVVAQ...APAKGAELI.VTVDN...GI--....S.....SH
66 ---.....----.....-----IPVAEM...AIEKGVQLL.MTVDN...GV--....S.....SF
67 ---.....----.....-----NELINT...ALEKKISLI.ITVDN...GI--....S.....SI
68 ---.....----.....-----STLIAK...LKEEGITLL.ITVDC...GI--....T.....AG
69 ---.....----.....-----SSLIAK...MKEEKVTLL.ITVDC...GI--....T.....AG
70 ---.....----.....-----ASLISQ...MLQDGISLL.ITVDC...GI--....T.....AG
71 ---.....----.....------KELMS...IFEKYGDFL.ITVDN...GT--....-.....--
72 PGL.....ERL-.....-----------...-ATQGTKLI.VTCDT...GS--....T.....NL
73 ---.....----.....-----CNAVDE...HAAAGGTLI.VTVDC...GI--....S.....NR
74 ---.....----.....---------ID...TIPDDVDLV.IIPDA...GS--....S.....QF
75 LAL.....NDLLsq9pkTNQLVRLDCIK...NQFQKNPLL.FSADL...GADLa...A.....NT
76 KKY.....RDK-.....------FRVIE...DLPDCFE-L.VLVDT...HF--....-.....--
77 IGE.....IKKY.....EELWSRFITPEeamEISNDDTLL.VIVDT...HK--....P.....SL
78 KDL.....FPF-.....-----EAAPID...DAFVKNSLA.IIFDT...S---....N.....QE
79 ---.....----.....----YSLDEVD...NETYEGALV.IVCDT...A---....N.....QE
80 INM.....TF--.....------TNQID...ESFLKEALA.IVVDA...NYKN....R.....IE
81 LEM.....VFTP.....KEQITPELM--...----QQALA.VIVDA...NYKE....R.....IE
82 ---.....----.....---PGVEDVIN...PDGKFYDVG.IVVDA...SG--....-.....--
83 KD-.....----.....---KFLSEWPN...IEISEYS-V.IILDC...SI-L....D.....RI
84 ATL.....FR--.....-----PSLSAQ...IRPSDQTAV.IVVDC...SE-L....S.....RV
85 LPG.....CHL-.....------LVRPE...VMRRDVDLV.VTVDI...PS-V....D.....RL
86 VKL.....TGLP.....AKRWGPQMLKD...IDLSDYQGC.VLVDS...QGTN....S.....QL
87 INL.....LGI-.....----KLLNVED...IDLDNYCVI.AVIDT...ST--....-.....--
88 VNL.....LEI-.....----PMIRAPE...VDLSHYDAF.AIVDS...SG--....-.....--
89 VNV.....LGME.....FRKVSR---GS...YEIKRHKAI.AIVDA...QP--....N.....GN
90 VAL.....SRVP.....IEKDPVI----...----KENVI.FIFDT...SS--....-.....-I
91 LNE.....IG--.....-----ERVDIE...IYPKLPETV.FIVDT...AS--....I.....NQ
92 --I.....DICL.....YNGIAVHLDTQ...TVPRMPDAL.VILDTpnpGMIY....A.....PP
93 YEI.....LNA-.....---------IA...QSKESEFLI.LVSDL...NLNL....Nea6lqDK
94 ---.....----.....---VQYFLEKA...KESNRQDAL.FITDL...AVNE....E.....NE
95 ---.....----.....-----SSLIAK...MKEEKVTLL.ITVDC...GI--....T.....AG
96 ---.....----.....-----EQAFRS...IKERGFSLI.ITVDT...GI--....A.....AV
97 ---.....----.....-----ASLISQ...MLQDGISLL.ITVDC...GI--....T.....AG
98 ---.....----.....-----PELAEI...AAAQGVDLL.ITVDN...GI--....A.....SI
99 ---.....----.....-----PEVVDQ...AHARGAQLI.VTVDN...GI--....S.....SH
100 ---.....----.....-----PEVVDQ...AIERGAEMI.MTVDN...GV--....S.....SL
101 ---.....----.....-----PEVVDQ...AHARGAQLI.VTVDN...GI--....S.....SH
102 ---.....----.....-----IPVAEM...AIEKGVQLL.MTVDN...GV--....S.....SF
103 ---.....----.....-----PEVVAQ...APAKGAELI.VTVDN...GI--....S.....SH
104 ---.....----.....-----STLIAK...LKEEGITLL.ITVDC...GI--....T.....AG
105 ---.....----.....-----PLAMQK...IKGNGTELL.ITVDC...GA--....M.....AH
106 YEL.....EDVT.....KDLVFSIEDAL...KFGQKLPLI.VLIDN...GSTD....E.....DI
107 ---.....----.....-----PELAEI...AAAQGVDLL.ITVDN...GI--....A.....SI
108 LEM.....VFTP.....KEQITPELM--...----QQALA.VIVDA...NYKE....R.....IE
109 ---.....----.....-----PENIST...FKENNVSCL.VTVDC...GI--....T.....AL
110 KD-.....----.....---KFLSEWPN...IEISEYS-V.IILDC...SI-L....D.....RI
111 YEL.....EDVV.....KDLSYALEDLE...RHGQKLPLL.VLLDN...GSTE....E.....DI
112 ---.....----.....-----TSLISQ...MLQDGVSLL.ITVDC...GI--....T.....AG
113 YEL.....EDVV.....RDLDESLEDAE...RHGDKIPLV.VLVDN...GSGL....E.....DV
114 ---.....----.....-----PALVDE...LAALQPDLL.VTVDH...GI--....A.....CH
115 INM.....T---.....-----FTNQID...ESFLKEALA.IVVDA...NYKN....R.....IE
116 ---.....----.....---ITIETIND...IPFKDYDLI.IFADL...GSGQlkmiK.....EK
117 ---.....----.....-----PELAEI...AAAQGVDLL.ITVDN...GI--....A.....SI
118 ---.....----.....-----SALVEE...LAPLQPALL.VTVDH...GI--....A.....CH
119 ---.....----.....-----NELINT...ALEKKISLI.ITVDN...GI--....S.....SI
120 ---.....----.....------KELMS...IFEKYGDFL.ITVDN...GT--....-.....--
121 ---.....----.....-----NELINT...ALEKKISLI.ITVDN...GI--....S.....SI
122 ---.....----.....-----AEIINE...---LDVNLI.ITVDN...GI--....A.....AL
123 ---.....----.....----YSLDEVD...NETYEGALV.IVCDT...A---....N.....QE
124 ---.....---S.....LPGCHLLVRPE...VMRRDVDLV.VTVDI...PS-V....D.....RL
125 ---.....----.....-----NELINT...ALEKKISLI.ITVDN...GI--....S.....SI
126 VKL.....TGLP.....AKRWGPQMLKD...IDLSDYQGC.VLVDS...QGTN....S.....QL
127 REL.....FPF-.....-----EQTDIN...DDFVKESLA.IIFDT...S---....N.....QE
128 KDL.....FPF-.....-----EAAPID...DAFVKNSLA.IIFDT...S---....N.....QE
129 YEL.....EDVL.....KDIIFMMEDHQ...RFGDELPLI.VIVDN...GGTS....E.....DI
130 YEL.....EDVL.....KDIIFMMEDHM...RFGDELPLV.VIVDN...GGTT....E.....DI
131 VNV.....LGME.....FR---KVSRGS...YEIKRHKAI.AIVDA...QP--....N.....GN
132 --I.....DICL.....YNGIAVHLDTQ...TVPRMPDAL.VILDTpnpGMIY....A.....PP
133 ---.....----.....---------ID...TIPDDVDLV.IIPDA...GS--....S.....QF
134 ---.....----.....------PDRVP...EHAAAADLV.VTVDC...GV--....S.....NL
135 ---.....----.....---VSEDLVRQ...LKDEDYKVF.IFSDL...GSGS....L.....SI
136 ---.....----.....---VSEELVRQ...LKDEEYKII.IFSDL...GSGS....L.....SL
137 IGE.....IKKY.....EELWSRFITPEeamEISNDDTLL.VIVDT...HK--....P.....SL
138 ---.....----.....---PGVEDVIN...PDGKFYDVG.IVVDA...SGFY....R.....VG
139 VNV.....LGME.....---FKKVLRGS...YEIKRYDAI.AIVDA...QP--....N.....GN
140 ---.....---Y.....ATLFRPSLSAQ...IRPSDQTAV.IVVDC...SE-L....S.....RV
141 ---.....----.....-----KEFIKK...LSGEKYSLF.FFCDM...GS--....-.....--
142 ---.....----.....-----------...----SSDLT.IFSDL...GS--....-.....-G
143 LALnd9ciFNPK.....TNQLVRLDYIK...NQFQKTPLL.FSADL...GADLv...S.....NI
144 ---.....----.....-----RPGLER...LATQGTKLI.VTCDT...GS--....T.....NL
145 ---.....----.....-----------...----QGELL.LFADM...GS--....-.....--
146 ---.....----.....---VYPAVVEK...IHSSRDGMI.IYTDL...GG--....L.....AA
147 LD-.....---Y.....FGIQAPPVVKS...AQAEGAKQV.ILTDH...NEFQ....Q.....SI
148 ---.....---I.....LNEIGERVDIE...IYPKLPETV.FIVDT...AS--....I.....NQ
149 LALnd9ciFNPK.....TNQLVRLDCIK...NQFQKNPLL.FSADL...GADLa...A.....NT
150 LALnd9ciFNPK.....TNQLVRLDCIK...NQFQKNPLL.FSADL...GADLa...A.....NT
151 KFL.....EKH-.....-----------...----HAPLI.ITVDN...GI--....N.....AF
152 ---.....----.....-----CNAVDE...HAAAGGTLI.VTVDC...GI--....S.....NR
153 --I.....PYVF.....EKFPYIDKIEE...NPNFDPELL.VVVDA...SSPD....R.....IG
154 ---.....---F.....LPQPGELTAPL...ESWPQGALA.AVLDV...DNND....P.....VR
155 LDY.....FK--.....---QESPRLVE...TAANEVNGV.ILVDH...NERQ....Q.....SI
156 LD-.....---Y.....FGVAAPRVITS...AKAEGAEQV.ILTDH...NEFQ....Q.....SV
157 VNL.....LE--.....---IPMIRAPE...VDLSHYDAF.AIVDS...SG--....-.....--
158 INL.....LG--.....---IKLLNVED...IDLDNYCVI.AVIDT...ST-S....K.....QL
159 VAL.....SRVP.....IEKDPVI----...----KENVI.FIFDT...SS--....-.....-I
160 LN-.....---V.....AGVEQPELRTS...VAGEQVWLV.DYTDL...A---....Q.....AP
161 KD-.....----.....-----------...----ENTFV.WFTDI...GS--....-.....--
162 FT-.....----.....---FDPNEVDD...EFIKD-SIA.FIVDT...A---....N.....QE
163 ---.....----.....---FRFDDRIR...KAIEHAERV.YILDL...NLPY....D.....VE
164 K--.....---V.....YSDRFEFVWDH...EFEGEITEL.VIVDA...PS-L....D.....RI
165 ---.....LEAV.....GEEFGPLCSPD...----ENPLIaVVVDA...ANLS....Q.....IA
166 AKE.....NEV-.....-----------...----NKPLF.IFADM...GS--....-.....--
167 EK-.....----.....FGFEVPEIMTN...G---EGKKV.ALVDH...SEKA....Q.....TV
168 KFL.....EKH-.....-----------...----HAPLI.ITVDN...GI--....N.....AF
169 LKF.....SRV-.....------PIERN...PKI-SERVV.FIFDT...SS-L....E.....QL
170 YEI.....LNA-.....---------IA...QSKESEFLI.LVSDL...NLNL....Nea6lqDK
171 ---.....----.....---VQYFLEKA...KESNRQDAL.FITDL...AVNE....E.....NE
172 YEI.....LNA-.....---------IA...QSKESEFLI.LVSDL...NLNL....Nea6lqDK
173 ENL.....TG-P.....IGEFRFDDRIW...KEIERAEEI.YVVDF...NV--....-.....--
174 ---.....----.....---------ID...ESFLKEALA.IVVDA...NYKN....R.....IE
175 REL.....----.....-GLEAPPLLTE...LPAG--SKV.ALVDH...NESA....Q.....SL
176 RK-.....----.....---FGVMEPEL...IESAKGKEI.ILVDH...SEKS....Q.....SF
177 ---.....----.....-----------...-------LA.VIVDA...NYKE....R.....IE
178 KKY.....RDK-.....---FRVIEDLP...----DCFEL.VLVDT...HFLP....E.....GL
100 110 120 130 140 150
| | | | | |
1 PAISKAKAYGIEV.IVIDHH.FPGEVVDgkv.EVDDYVDAHVNPYLVGG.DSNLTAGVLGTEIA-
2 LALMKAKIYDIEI.VVVDHH.YPGEVQDgrv.EVDEYVDTHVNPYLVGG.DSQITAGSLSVEIA-
3 PAYKRLKAYGVKI.VVIDHH.DPRDWISedkaKVDEYVDVHVNPHH---.---VKRGYYELTAGM
4 PAIRQFLLFGADV.ITIDHH.FPDE---....EVDSYLLYHVNPYKVGG.DSNYTSGVLCVEIA-
5 DMIDKINAGKSMV.LIIDHH.PAKD---....-IDSDYVHVLDPELAGI.SGD-----VFVSASS
6 GQIEEIIKHNFNA.IILDHH.PPVIKDS....F-INENIIQLNPHIFGV.DGS-----REITASG
7 AYLEEISRLKGDV.IVADHH.QPSE---....SEAGPHVVHINPHLHGL.DGS-----RDLSASG
8 IGEHL---KDKSV.VILDHH.PPEP---....VETHEKHILANPVQFGA.NSV-----RDLSGSG
9 GYADLISQVDTDV.VILDHH.IPNG--E....IRPKRNLAHVNPHLVGM.DGT-----FELSASG
10 --GVLNMLDGIEF.AITDHH.LPQS---....----HHPMQLNPHDFGY.DGA-----FELSGAT
11 LDELNLSDKRDKI.IILDHH.QPEE---....IKIPKTIIHINPLTIAK.SGA------EICGAG
12 QRVHENLKSNSRV.LILDHH.PPVRKMNf...TAPSGDFLEINPIFYGM.DGS-----THVSGGG
13 GIE-------KET.VFIDHH.IQPK---....-IKNPRVRQINPSLEGKeSPSASFVVSEYFDV-
14 EAARFCKEKNYTL.IITDHH.CLHH---....DEVPDAYAVINPKQ---.-PDCDFIQKEVCGAL
15 DALKYAKDVKLDV.IVIDHH.ISTE---....-ILPDAVAIVNPNR---.-IDETSEYKYLAAVG
16 HEAKVAKELGLDV.IITDHH.EPGP---....-ELPDVRAIVHPKQ---.-PGCTYPFKELAGVG
17 AGVEHARSLGIPV.IVTDHH.LPGD---....-TLPAAEAIINPNL---.-RDCNFPSKSLAGVG
18 AGVDDAHRRGIAV.VVTDHH.LPGE---....-TLPAAEAMINPNL---.-SDCAFPSKALAGVG
19 DGVAFLKEKGIRV.LVTDHH.LPPE---....-TLPPADAIVNPNL---.-SQCGFPSKSLAGVG
20 EEINYANSKGIEI.IITDHH.LPGE---....-NFKTENIVINPHL---.-KDDKYPFKEIAGCC
21 KEVSDITRQGIDV.IITDHH.MPTG---....-KIPHCVATLNPKL---.-RDHTYPNRELTGVG
22 KEVSDINKQGIDV.IITDHH.MPTG---....-KIPHCIATLNPKL---.-RDRAYPNKELTGVG
23 KEVHAINKQGIDV.IVTDHH.MPTG---....-KLPHCVAMLNPKL---.-DKNPYPNKELTGVG
24 SAVEEIDQSSLET.VVIDHH.NVPP---....-RIPKKALIVNPKV---.-GAKREGLKALSSSA
25 DEIVYAQQLGMDV.IVTDHH.TLPD---....-DRPEVVAIINPRY---.-FADGHPLFNLSGVA
26 AEIAYARHRGIDV.LVIDHH.AAPE---....--TLPDAIIINAKV---.-PGAGYPHEFLSGCA
27 EEHEALNKRGTEI.IVIDHH.ECER---....--VSEHAIVVNNQL---.--SPNYSNKTLTGAG
28 ELQEILLEHFEQC.IITDHH.KSFE-VD....WIDENKIAYINLND---.-EKDANYYSGAFTSA
29 LPEGLPRERIKRI.IVYDHH.PIGD---....--VKEFEGKIEKV----.-GAATTLVVEEIKE-
30 VMEERLVNKIEHI.VVIDHH.RRGE--E....FIRDPLLVYMEPYA---.-SSTAELVTELLEY-
31 RVLTQKHKLAKET.VRIDHH.PKTE---....--SFADLEWIDPAF---.-SAAAEMVGYLILQ-
32 RIDDQRYPSGAKL.MKIDHH.PNED---....--PYGDLLWVDTSA---.-SSVSEMIYELYLEG
33 LRELLDKNLFKAV.LRIDHH.PNED---....-DLNTSFNFVEESY---.-VACCEQIVEMATV-
34 CRDLLDQNQFKAV.LRIDHH.PNED---....-DLNTTHNFVDASY---.-IAAAEQVVDLAVQ-
35 FYRVGKEVKVGKR.IRIDHH.VGGE---....--FYGMHDYIDPTA---.-PATAALVYEIIKNW
36 GDEFIFYVKNMPT.LVIDHH.MSGE---....--KLECEGYIDPFA---.-PSTTFLIEKLIRE-
37 GAELASQLAPFAR.AFIDHH.ETCG---....--DHCAHSFVVKTA---.-PSTTTLVQTLIET-
38 GALGDLTDSGREL.LVIDHH.ASND---....--LFGTANFIDPSA---.-DSTTTMVAEILDA-
39 MPLVQEANIPV-V.VIIDHH.SPQD--E....VEAEGAFVDIRPSS---.-RSTATILTEYLQGG
40 SKQLPIELPNID-.IIIDHH.NNTD---....--LTAKYMDVRPEV---.-GATASILTQYLME-
41 PGVNNSIPPDIDIsIVIDHH.PAEK---....--VVAEFVDLREDV---.-GATATILTEYIKE-
42 ITILDEEDLNKIE.IIIDHHqILQNLRE....KLPPNCFVDIRTDV---.-NATSSIMAEYLKA-
43 EQLEPIEVPPAKI.VVIDHH.VEKE---....NPIPADVAIIDPTR---.-TSTAEIVWELFKK-
44 LKVNFDELKEREV.ILIDHH.KKTD---....LADICKYYIIKEDY---.-PSTSEIIAEIFKE-
45 SCRLLLSDSTIRK.IELDHH.LFANAAC....CGDPGYSLIARA-----.-SSTCEIIAYLCYKL
46 IQEHRLQNKNIQI.QLLDHH.ISGKEVA....ESFHWYFLDINRCA---.----TKIVYEFLKKH
47 ERLNEYVHAGGKV.KLIDHH.KTALHLN....E-HEWGFVQVEYDDGRL.TSATSLLYGYLIENG
48 PAISKAKAYGIEV.IVIDHH.FPGEVVDgkv.EVDDYVDAHVNPYLVGG.DSNLTAGVLGTEIA-
49 LALMKAKIYDIEI.VVVDHH.YPGEVQDgrv.EVDEYVDTHVNPYLVGG.DSQITAGSLSVEIA-
50 PAYKRLKAYGVKI.VVIDHH.DPRDWISedkaKVDEYVDVHVNPHH---.---VKRGYYELTAGM
51 PAIRQFLLFGADV.ITIDHH.FPDE---....EVDSYLLYHVNPYKVGG.DSNYTSGVLCVEIA-
52 DMIDKINAGKSMV.LIIDHH.PAKD---....-IDSDYVHVLDPELAGI.SGD-----VFVSASS
53 GQIEEIIKHNFNA.IILDHH.PPVIKDS....F-INENIIQLNPHIFGV.DGS-----REITASG
54 AYLEEISRLKGDV.IVADHH.QPSE---....SEAGPHVVHINPHLHGL.DGS-----RDLSASG
55 IGEHL---KDKSV.VILDHH.PPEP---....VETHEKHILANPVQFGA.NSV-----RDLSGSG
56 GYADLISQVDTDV.VILDHH.IPNG--E....IRPKRNLAHVNPHLVGM.DGT-----FELSASG
57 --GVLNMLDGIEF.AITDHH.LPQS---....----HHPMQLNPHDFGY.DGA-----FELSGAT
58 LDELNLSDKRDKI.IILDHH.QPEE---....IKIPKTIIHINPLTIAK.SGA------EICGAG
59 QRVHENLKSNSRV.LILDHH.PPVRKMNf...TAPSGDFLEINPIFYGM.DGS-----THVSGGG
60 GIE-------KET.VFIDHH.IQPK---....-IKNPRVRQINPSLEGKeSPSASFVVSEYFDV-
61 EAARFCKEKNYTL.IITDHH.CLHH---....DEVPDAYAVINPKQ---.-PDCDFIQKEVCGAL
62 DALKYAKDVKLDV.IVIDHH.ISTE---....-ILPDAVAIVNPNR---.-IDETSEYKYLAAVG
63 HEAKVAKELGLDV.IITDHH.EPGP---....-ELPDVRAIVHPKQ---.-PGCTYPFKELAGVG
64 AGVEHARSLGIPV.IVTDHH.LPGD---....-TLPAAEAIINPNL---.-RDCNFPSKSLAGVG
65 AGVDDAHRRGIAV.VVTDHH.LPGE---....-TLPAAEAMINPNL---.-SDCAFPSKALAGVG
66 DGVAFLKEKGIRV.LVTDHH.LPPE---....-TLPPADAIVNPNL---.-SQCGFPSKSLAGVG
67 EEINYANSKGIEI.IITDHH.LPGE---....-NFKTENIVINPHL---.-KDDKYPFKEIAGCC
68 KEVSDITRQGIDV.IITDHH.MPTG---....-KIPHCVATLNPKL---.-RDHTYPNRELTGVG
69 KEVSDINKQGIDV.IITDHH.MPTG---....-KIPHCIATLNPKL---.-RDRAYPNKELTGVG
70 KEVHAINKQGIDV.IVTDHH.MPTG---....-KLPHCVAMLNPKL---.-DKNPYPNKELTGVG
71 SAVEEIDQSSLET.VVIDHH.NVPP---....-RIPKKALIVNPKV---.-GAKREGLKALSSSA
72 DEIVYAQQLGMDV.IVTDHH.TLPD---....-DRPEVVAIINPRY---.-FADGHPLFNLSGVA
73 AEIAYARHRGIDV.LVIDHH.AAPE---....--TLPDAIIINAKV---.-PGAGYPHEFLSGCA
74 EEHEALNKRGTEI.IVIDHH.ECER---....--VSEHAIVVNNQL---.--SPNYSNKTLTGAG
75 ELQEILLEHFEQC.IITDHH.KSFE-VD....WIDENKIAYINLND---.-EKDANYYSGAFTSA
76 LPEGLPRERIKRI.IVYDHH.PIGD---....--VKEFEGKIEKV----.-GAATTLVVEEIKE-
77 VMEERLVNKIEHI.VVIDHH.RRGE--E....FIRDPLLVYMEPYA---.-SSTAELVTELLEY-
78 RVLTQKHKLAKET.VRIDHH.PKTE---....--SFADLEWIDPAF---.-SAAAEMVGYLILQ-
79 RIDDQRYPSGAKL.MKIDHH.PNED---....--PYGDLLWVDTSA---.-SSVSEMIYELYLEG
80 LRELLDKNLFKAV.LRIDHH.PNED---....-DLNTSFNFVEESY---.-VACCEQIVEMATV-
81 CRDLLDQNQFKAV.LRIDHH.PNED---....-DLNTTHNFVDASY---.-IAAAEQVVDLAVQ-
82 FYRVGKEVKVGKR.IRIDHH.VGGE---....--FYGMHDYIDPTA---.-PATAALVYEIIKNW
83 GDEFIFYVKNMPT.LVIDHH.MSGE---....--KLECEGYIDPFA---.-PSTTFLIEKLIRE-
84 GAELASQLAPFAR.AFIDHH.ETCG---....--DHCAHSFVVKTA---.-PSTTTLVQTLIET-
85 GALGDLTDSGREL.LVIDHH.ASND---....--LFGTANFIDPSA---.-DSTTTMVAEILDA-
86 MPLVQEANIPV-V.VIIDHH.SPQD--E....VEAEGAFVDIRPSS---.-RSTATILTEYLQGG
87 SKQLPIELPNID-.IIIDHH.NNTD---....--LTAKYMDVRPEV---.-GATASILTQYLME-
88 PGVNNSIPPDIDIsIVIDHH.PAEK---....--VVAEFVDLREDV---.-GATATILTEYIKE-
89 ITILDEEDLNKIE.IIIDHHqILQNLRE....KLPPNCFVDIRTDV---.-NATSSIMAEYLKA-
90 EQLEPIEVPPAKI.VVIDHH.VEKE---....NPIPADVAIIDPTR---.-TSTAEIVWELFKK-
91 LKVNFDELKEREV.ILIDHH.KKTD---....LADICKYYIIKEDY---.-PSTSEIIAEIFKE-
92 SCRLLLSDSTIRK.IELDHH.LFANAAC....CGDPGYSLIARA-----.-SSTCEIIAYLCYKL
93 IQEHRLQNKNIQI.QLLDHH.ISGKEVA....ESFHWYFLDINRCA---.----TKIVYEFLKKH
94 ERLNEYVHAGGKV.KLIDHH.KTALHLN....E-HEWGFVQVEYDDGRL.TSATSLLYGYLIENG
95 KEVSDINKQGIDV.IITDHH.MPTG---....-KIPHCIATLNPKL---.-RDRAYPNKELTGVG
96 HEAKVAKELGLDV.IITDHH.EPGP---....-ELPDVRAIVHPKQ---.-PGCTYPFKELAGVG
97 KEVHAINKQGIDV.IVTDHH.MPTG---....-KLPHCVAMLNPKL---.-DKNPYPNKELTGVG
98 AGVARAQALGLDV.IVTDHH.LPAE---....--TVPDCIIVNPNQ---.-KGCGFPSKSLAGVG
99 AGVEHARSLGIPV.IVTDHH.LPGD---....-TLPAAEAIINPNL---.-RDCNFPSKSLAGVG
100 EGVRYAKQKGLQV.VVTDHH.LPGQ---....-ELPEVDAMVNPNL---.-QQCAFPSKALAGVG
101 AGVEHARSLGIPV.IVTDHH.LPGD---....-TLPAAEAIINPNL---.-RDCNFPSKSLAGVG
102 DGVAFLKEKGIRV.LVTDHH.LPPE---....-TLPPADAIVNPNL---.-SQCGFPSKSLAGVG
103 AGVDDAHRRGIAV.VVTDHH.LPGE---....-TLPAAEAMINPNL---.-SDCAFPSKALAGVG
104 KEVSDITRQGIDV.IITDHH.MPTG---....-KIPHCVATLNPKL---.-RDHTYPNRELTGVG
105 DALKYAKDVKLDV.IVIDHH.ISTE---....-ILPDAVAIVNPNR---.-IDETSEYKYLAAVG
106 PAISKAKAYGIEV.IVIDHH.FPGEVVDgkv.EVDDYVDAHVNPYLVGG.DSNLTAGVLGTEIA-
107 AGVARAQALGLDV.IVTDHH.LPAE---....--TVPDCIIVNPNQ---.-KGCGFPSKSLAGVG
108 CRDLLDQNQFKAV.LRIDHH.PNED---....-DLNTTHNFVDASY---.-IAAAEQVVDLAVQ-
109 DSVALAKKFGMKV.IVTDHH.EVNG---....-DLPPADAIVNPKV---.-PGENYPFRDLAGVG
110 GDEFIFYVKNMPT.LVIDHH.MSGE---....--KLECEGYIDPFA---.-PSTTFLIEKLIRE-
111 LALMKAKIYDIEI.VVVDHH.YPGEVQDgrv.EVDEYVDTHVNPYLVGG.DSQITAGSLSVEIA-
112 REVRSINKQGIDV.IVTDHH.TPTG---....-KLPHCIATLNPKL---.-DKNSYPNKELTGVG
113 PAIRQFLLFGADV.ITIDHH.FPDE---....EVDSYLLYHVNPYKVGG.DSNYTSGVLCVEIA-
114 AGVAAAKARGWTV.LVTDHH.LPGE---....-VLPPADAIVDPNL---.-VQDSFPSKTLAGVG
115 LRELLDKNLFKAV.LRIDHH.PNED---....-DLNTSFNFVEESY---.-VACCEQIVEMATV-
116 LDELNLSDKRDKI.IILDHH.QPEE---....IKIPKTIIHINPLTIAK.SGA------EICGAG
117 AGVARAQALGLDV.IVTDHH.LPAD---....--TVPDCIIVNPNQ---.-KGCGFPSKSLAGVG
118 AGVAAAKARGWQV.LVTDHH.LPGE---....-ILPPADVIVNPNL---.-PGDLFPSKTLAGVG
119 EEINYANSKGIEI.IITDHH.LPGE---....-NFKTENIVINPHL---.-KDDKYPFKEIAGCC
120 SAVEEIDQSSLET.VVIDHH.NVPP---....-RIPKKALIVNPKV---.-GAKREGLKALSSSA
121 EEINYANSKGIEI.IITDHH.LPGE---....-NFKTENIVINPHL---.-KDDKYPFKEIAGCC
122 EAAKLCKEKNIDL.IITDHH.MPQD---....-ILPDAFAIINPKQ---.-KDCDFPEIEICGAQ
123 RIDDQRYPSGAKL.MKIDHH.PNED---....--PYGDLLWVDTSA---.-SSVSEMIYELYLEG
124 GALGDLTDSGREL.LVIDHH.ASND---....--LFGTANFIDPSA---.-DSTTTMVAEILDA-
125 EEINYANSKGIEI.IITDHH.LPGE---....-NFKTENIVINPHL---.-KDDKYPFKEIAGCC
126 MPLVQEANIPV-V.VIIDHH.SPQD--E....VEAEGAFVDIRPSS---.-RSTATILTEYLQGG
127 RVLTQKHKLAKET.VRIDHH.PRTE---....--KFADMEWIDSSF---.-SATAEMIGYLILQ-
128 RVLTQKHKLAKET.VRIDHH.PKTE---....--SFADLEWIDPAF---.-SAAAEMVGYLILQ-
129 PAYKRLKAYGVKI.VVIDHH.DPREWISedkaKVDEYVDVHVNPHH---.---VKRGYYELTAGM
130 PAYKRLKAYGVKI.VVIDHH.DPRDWISedkaKVDEYVDVHVNPHH---.---VKRGYYELTAGM
131 ITILDEEDLNKIE.IIIDHHqILQNLRE....KLPPNCFVDIRTDV---.-NATSSIMAEYLKA-
132 SCRLLLSDSTIRK.IELDHH.LFANAAC....CGDPGYSLIARA-----.-SSTCEIIAYLCYKL
133 EEHEALNKRGTEI.IVIDHH.ECER---....--VSEHAIVVNNQL---.--SPNYSNKTLTGAG
134 DEVKSLLATGTEV.VVTDHH.APGE---....--NFPECLVVHPHL---.TPDYDPDRHNLTGAG
135 IKEHL---KDRTV.IILDHH.PPEN---....VELPEKHILVNPVQFGA.NSV-----RDLSGSG
136 IGEHL---KDKSV.VILDHH.PPEP---....VETHEKHILANPVQFGA.NSV-----RDLSGSG
137 VMEERLVNKIEHI.VVIDHH.RRGE--E....FIRDPLLVYMEPYA---.-SSTAELVTELLEY-
138 KEV-----KVGKR.IRIDHH.VGGE---....--FYGMHDYIDPTA---.-PATAALVYEIIKNW
139 ITILDDDDLKRVE.IIVDHHqILQNLRE....KLSPNCFVDIRTDV---.-NATSSIMVEYLKA-
140 GAELASQLAPFAR.AFIDHH.ETCG---....--DHCAHSFVVKTA---.-PSTTTLVQTLIET-
141 AYLEEISRLKGDV.IVADHH.QPSE---....SEAGPHVVHINPHLHGL.DGS-----RDLSASG
142 QRVHENLKSNSRV.LILDHH.PPVRKMNf...TAPSGDFLEINPIFYGM.DGS-----THVSGGG
143 ELQKILLERFEQC.IITDHH.KSFE-VD....WIDKNKIAYINLND---.-EKDAN---YYSGAF
144 DEIVYAQQLGMDV.IVTDHH.TLPD---....-DRPEVVAIINPRY---.-FADGHPLFNLSGVA
145 GYADLISQVDTDV.VILDHH.IPNG--E....IRPKRNLAHVNPHLVGM.DGT-----FELSASG
146 DMIDKINAGKSMV.LIIDHH.PAKD---....-IDSDYVHVLDPELAGI.SGD-----VFVSASS
147 ADIREVEV----V.EVVDHH.RVAN--F....ETANPLYMRLEPV----.-GSASSIVYRLYKE-
148 LKVNFDELKEREV.ILIDHH.KKTD---....LADICKYYIIKEDY---.-PSTSEIIAEIFKE-
149 ELQEILLEHFEQC.IITDHH.KSFE-VD....WIDENKIAYINLND---.-EKDAN---YYSGAF
150 ELQEILLEHFEQC.IITDHH.KSFE-VD....WIDENKIAYINLND---.-EKDAN---YYSGAF
151 EAARFCKEKNYTL.IITDHH.CLHH---....DEVPDAYAVINPKQ---.-PDCDFIQKEVCGAL
152 AEIAYARHRGIDV.LVIDHH.AAPE---....--TLPDAIIINAKV---.-PGAGYPHEFLSGCA
153 KFQDLLDK--VPS.VVIDHH.STNT---....--NFGNWNWVDPSF---.-AATAQMIFRINKA-
154 VAGADLTQFDGPV.VNVDHH.GTNL---....--RRADAGVVDPSK---.-PAAAMMVADVIDA-
155 KDIEEVQV----L.EVIDHH.RIAN--F....ETAEPLYYRAEPV----.-GCTATILNKMYKE-
156 ADIAEVEV----Y.GVVDHH.RVAN--F....ETANPLYMRLEPV----.-GSASSIVYRMFKE-
157 PGVNNSIPPDIDIsIVIDHH.PAEK---....--VVAEFVDLREDV---.-GATATILTEYIKE-
158 PIELPNID-----.IIIDHH.NNTD---....--LTAKYMDVRPEV---.-GATASILTQYLME-
159 EQLEPIEVPPAKI.VVIDHH.VEKE---....NPIPADVAIIDPTR---.-TSTAEIVWELFKK-
160 DDLNQAEI----L.GIVDHH.RLGD--V....MTVNPLEAWIWPV----.-GCTSTILFNLFKM-
161 --GVLNMLDGIEF.AITDHH.LPQS---....----HHPMQLNPHDFGY.DGA-----FELSGAT
162 RVLSQKHRLAKKT.ILVDHH.VKTI---....--TYTDLEYINDQS---.-IAACEMIAYSLMH-
163 GIEKE-------T.VFIDHH.IQPK---....-IKNPRVRQINPSLEGKeSPSASFVVSEYFDV-
164 PESIRKKAQGAKI.TVYDHH.VDES---....----PYDGIVSKV----.-GATITILVELIRE-
165 GAESLFRAARL-K.VVIDHH.ERGS---....IHEEADVALVDPGA---.-GSSSELAVKTAVE-
166 GQIEEIIKHNFNA.IILDHH.PPVI-KD....SFINENIIQLNPHIFGV.DGS-----REITASG
167 DGIDKAEV----V.AIVDHH.KIGD---....VTTPQPILFVNLPV---.-GCTATVIKLLFDK-
168 EAAQFCKEKNYTL.IITDHH.CLHH---....DEIPDAYAVINPKQ---.-PDCDFIQKEVCGAL
169 --EPIKIPPNAKL.IVIDHH.VEKE---....NPIPADISVIDPKR---.-TSTAEIVWELFKK-
170 IQEHRLQNKNIQI.QLLDHH.ISGKEVA....ESFHWYFLDINRCA---.----TKIVYEFLKKH
171 ERLNEYVHAGGKV.KLIDHH.KTALHLN....E-HEWGFVQVEYDDGRL.TSATSLLYGYLIEN-
172 IQEHRLQNKDIQI.QLLDHH.ISGKEVA....ESFHWYFLDTNRCA---.----TKIVYEFLKKY
173 --PREAEKLRVPT.VFIDHH.SQPR---....-IKNPLVKHVNPVLEGRyYPSASFVVSEYLNY-
174 LRELLDKNLFKAV.LRIDHH.PNED---....-DLNTSFNFVEESY---.-VACCEQIVEMATV-
175 PALGELDV----T.RVVDHH.KLGD--L....TTINPPYLRFEPV----.-GCTGTILLKLHRE-
176 DDLEEGKL----I.AIIDHH.KVGL---....TTTEPILYYAKPV----.-GSTATVIAELYFKD
177 CRDLLDQNQFKAV.LRIDHH.PNED---....-DLNTTHNFVDASY---.-IAAAEQVVDLAVQ-
178 PRERI-----KRI.IVYDHH.PIGD---....--VKEFEGKIEKV----.-GAATTLVVEEIKE-
160 170 180
| | |
1 -------RMINP..DV.....E.....DEIKHIPGIAVVGD---hak...
2 -------KMINP..EI.....A.....ERILHLPGIAAVGD---han...
3 LATEVARYVNPA..VE.....D.....KIKHLPAIAG-------tg6sk.
4 ----------RM..IS.....D.....LDMKHLAAISVVGD---rae...
5 LNYIFFRAVAGE..E-.....A.....KKYAYIAVLGSVGDY--hd....
6 VCYLV----ARE..FG.....Y.....YDLSVLAIVGIIGDMQ-y.....
7 TAYL-----ATR..LL.....N.....RKTAPLALVGALGDMQ-y.....
8 VSYFFAREL--N..EM.....N.....KDLAYIAIVGAVGDMQ-e.....
9 VCYFFA---NEL..GR.....N.....RELASVALIGALGDKQR......
10 TTYLVSKYLRNG..RTlf7ndN.....SDLLPISIVGAVGDLQ-d.....
11 VSYLFAKAINND..WI.....D.....--LAKYAVLGAVGDIQN......
12 LTYLL----ARE..FG.....Y.....RDLSWMGLLAAVGDMQN......
13 ------------..--.....-.....--WNTWTALGAVGDVG-e.....
14 VAFYLCYGIHQL..LG.....KekshsSELLCLAGVATIADMMP......
15 VTFLFATAILSN..LK.....Kr13nlMKYLDLVALGTVCDMM-k.....
16 VAFKLAHALLGE..LP.....D.....-ELLDLAAIGTIADLV-p.....
17 VAFYLMLALRTF..LR.....Dq14nlAELLDLVALGTVADVV-p.....
18 VAFYLMMALRAN..LR.....Ec14nlAELLDLVALGTVADVV-p.....
19 VAFYLMLAVRAK..FR.....El12nfTDLLDLVALGTIADVV-p.....
20 VSFKACLA----..--.....-.....-----------------l165p.
21 VAFKLARGVLNA..LI.....Sr11slKKLLDLVTLGTITDVG-v.....
22 VAFKLARGVLNA..LR.....Ken9dtKHLLDLVTLGTVTDVG-t.....
23 VAFKLVCATYEE..LI.....Qq11dlLRFLDLVSLGTIADVGR......
24 LSFYLGSALIRE..FNlded.P.....RNFLDLVALGLLADYMP......
25 VAFKLVEALYNQ..YP.....Tvp6plEDLLDLVAIGLIADL--vt....
26 TAWKVVTA----..--.....-.....-----------------l167v.
27 MAYKFCQAIDEK..LN.....Knea..EQFLDLVSIGNIAD---sad...
28 LVFSQIFQTQTT..PL.....E.....EELIAITLLS-------drid..
29 ---------KGI..DI.....N.....PRDATLLAFGIYEDTGN......
30 -------QPKRL..KI.....N.....MIEATALLAGIIVDT--ks....
31 ---------MGY..EL.....N.....AEMAAYIYAGIITDTQR......
32 KE-------HGW..KL.....N.....TKAAELIYAGIVGDTGR......
33 ---------AKW..TI.....P.....PVAATLLYIGIYTDSN-r.....
34 ---------AKW..KL.....S.....PPAATALYLGIYTDSN-r.....
35 ---------DET..AI.....D.....KDIATCIYTGLATDTG-f.....
36 ---------FGH..DL.....T.....KEEAWYILVGFCTDTG-f.....
37 ---------MAG..SL.....E.....AAEARALFLGLATDTG-f.....
38 ---------WGK..PI.....D.....PRVAHCIYAGLATDTG-s.....
39 MLDFN----SSN..PT.....H.....VKCATALMHGLRSDTI-n.....
40 ---------LDI..EP.....S.....RNLATALFYGIQSDT--dy....
41 ---------LKI..TP.....S.....KILATALFFGIKS----etde..
42 ---------LEI..PI.....T.....ETLATALFYGMYIDT--kk....
43 ----------FN..YS.....D.....ENSAKALLAGIISDTS-n.....
44 ---------LNI..FP.....P.....KNVRIALLCGIVYDT--kh....
45 ARNHAQRTALGIrnLY.....S.....RNVVLSILTGMIGD---akt...
46 YA----------..--.....-.....-----------------i19ns.
47 ------------..--.....-.....-----------------f17rq.
48 -------RMINP..DV.....E.....DEIKHIPGIAVVGD---hak...
49 -------KMINP..EI.....A.....ERILHLPGIAAVGD---han...
50 LATEVARYVNPA..VE.....D.....KIKHLPAIAG-------tg6sk.
51 ----------RM..IS.....D.....LDMKHLAAISVVGD---rae...
52 LNYIFFRAVAGE..E-.....A.....KKYAYIAVLGSVGDY--hd....
53 VCYLV----ARE..FG.....Y.....YDLSVLAIVGIIGDMQ-y.....
54 TAYL-----ATR..LL.....N.....RKTAPLALVGALGDMQ-y.....
55 VSYFFAREL--N..EM.....N.....KDLAYIAIVGAVGDMQ-e.....
56 VCYFFA---NEL..GR.....N.....RELASVALIGALGDKQR......
57 TTYLVSKYLRNG..RTlf7ndN.....SDLLPISIVGAVGDLQ-d.....
58 VSYLFAKAINND..WI.....D.....--LAKYAVLGAVGDIQN......
59 LTYLL----ARE..FG.....Y.....RDLSWMGLLAAVGDMQN......
60 ------------..--.....-.....--WNTWTALGAVGDVG-e.....
61 VAFYLCYGIHQL..LG.....KekshsSELLCLAGVATIADMMP......
62 VTFLFATAILSN..LK.....Kr13nlMKYLDLVALGTVCDMM-k.....
63 VAFKLAHALLGE..LP.....D.....-ELLDLAAIGTIADLV-p.....
64 VAFYLMLALRTF..LR.....Dq14nlAELLDLVALGTVADVV-p.....
65 VAFYLMMALRAN..LR.....Ec14nlAELLDLVALGTVADVV-p.....
66 VAFYLMLAVRAK..FR.....El12nfTDLLDLVALGTIADVV-p.....
67 VSFKACLA----..--.....-.....-----------------l165p.
68 VAFKLARGVLNA..LI.....Sr11slKKLLDLVTLGTITDVG-v.....
69 VAFKLARGVLNA..LR.....Ken9dtKHLLDLVTLGTVTDVG-t.....
70 VAFKLVCATYEE..LI.....Qq11dlLRFLDLVSLGTIADVGR......
71 LSFYLGSALIRE..FNlded.P.....RNFLDLVALGLLADYMP......
72 VAFKLVEALYNQ..YP.....Tvp6plEDLLDLVAIGLIADL--vt....
73 TAWKVVTA----..--.....-.....-----------------l167v.
74 MAYKFCQAIDEK..LN.....Knea..EQFLDLVSIGNIAD---sad...
75 LVFSQIFQTQTT..PL.....E.....EELIAITLLS-------drid..
76 ---------KGI..DI.....N.....PRDATLLAFGIYEDTGN......
77 -------QPKRL..KI.....N.....MIEATALLAGIIVDT--ks....
78 ---------MGY..EL.....N.....AEMAAYIYAGIITDTQR......
79 KE-------HGW..KL.....N.....TKAAELIYAGIVGDTGR......
80 ---------AKW..TI.....P.....PVAATLLYIGIYTDSN-r.....
81 ---------AKW..KL.....S.....PPAATALYLGIYTDSN-r.....
82 ---------DET..AI.....D.....KDIATCIYTGLATDTG-f.....
83 ---------FGH..DL.....T.....KEEAWYILVGFCTDTG-f.....
84 ---------MAG..SL.....E.....AAEARALFLGLATDTG-f.....
85 ---------WGK..PI.....D.....PRVAHCIYAGLATDTG-s.....
86 MLDFN----SSN..PT.....H.....VKCATALMHGLRSDTI-n.....
87 ---------LDI..EP.....S.....RNLATALFYGIQSDT--dy....
88 ---------LKI..TP.....S.....KILATALFFGIKS----etde..
89 ---------LEI..PI.....T.....ETLATALFYGMYIDT--kk....
90 ----------FN..YS.....D.....ENSAKALLAGIISDTS-n.....
91 ---------LNI..FP.....P.....KNVRIALLCGIVYDT--kh....
92 ARNHAQRTALGIrnLY.....S.....RNVVLSILTGMIGD---akt...
93 YA----------..--.....-.....-----------------i19ns.
94 ------------..--.....-.....-----------------f17rq.
95 VAFKLARGVLNA..LR.....Ken9dtKHLLDLVTLGTVTDVG-......
96 VAFKLAHALLGE..LP.....D.....-ELLDLAAIGTIADLV-......
97 VAFKLVCATYEE..LI.....Qq11dlLRFLDLVSLGTIADVGR......
98 VIFYVLMALRAE..LR.....Rr13nlGELLDLVALGTVADVVP......
99 VAFYLMLALRTF..LR.....Dq14nlAELLDLVALGTVADVVP......
100 VAFYLMMALCVH..MR.....Qq14klMELIDLVALGTVADVVP......
101 VAFYLMLALRTF..LR.....Dq14nlAELLDLVALGTVADVVP......
102 VAFYLMLAVRAK..FR.....El12nfTDLLDLVALGTIADVVP......
103 VAFYLMMALRAN..LR.....Ec14nlAELLDLVALGTVADVVP......
104 VAFKLARGVLNA..LI.....Sr11slKKLLDLVTLGTITDV--......
105 VTFLFATAILSN..LK.....Kr13nlMKYLDLVALGTVCDMM-......
106 -------RMINP..DV.....E.....DEIKHIPGIAVVGD---......
107 VIFYVLMALRAE..LR.....Rr13nlGDLLDLVALGTVADV--......
108 ---------AKW..KL.....S.....PPAATALYLGIYTDSN-......
109 VTYKLVQALSEA..TN.....Yphp..ERFLELVALGTVADMV-......
110 ---------FGH..DL.....T.....KEEAWYILVGFCTDTG-......
111 -------KMINP..EI.....A.....ERILHLPGIAAVGD---......
112 VAFKLVCATYEE..LI.....Kq11dlLHFLDLVSLGTIADVGR......
113 ----------RM..IS.....D.....LDMKHLAAISVVGD---......
114 VIFYVLLALRGV..LR.....Ar12dlSVLLDLVAVGTVADLV-......
115 ---------AKW..TI.....P.....PVAATLLYIGIYTDSN-......
116 VSYLFAKAINND..WI.....D.....--LAKYAVLGAVGDIQN......
117 VIFYVLTALRAE..LR.....Rr13nlGGLLDLVALGTVADVVP......
118 VIFYVLLALRAR..LY.....Pv25dlTSLLDLVAVGTVADLV-......
119 VSFKACLAL---..--.....-.....-----------------......
120 LSFYLGSALIRE..FNlded.P.....RNFLDLVALGLLADYMP......
121 VSFKACLAL---..--.....-.....-----------------......
122 VAWYLIAALKEVc.-K.....Lkydm.CKFLELLAIAIVADMM-......
123 KE-------HGW..KL.....N.....TKAAELIYAGIVGDTGR......
124 ---------WGK..PI.....D.....PRVAHCIYAGLATDTG-......
125 VSFKACLAL---..--.....-.....-----------------......
126 MLDFN----SSN..PT.....H.....VKCATALMHGLRSDTI-......
127 ---------MGY..KL.....N.....DEIASYLYAGIITDTQR......
128 ---------MGY..EL.....N.....AEMAAYIYAGIITDTQR......
129 LATEVARFI-NP..EV.....E.....DKIKHLPAIAGTGD---......
130 LATEVARYV-NP..AV.....E.....DKIKHLPAIAGTGD---......
131 ---------LEI..PI.....T.....ETLATALFYGMYIDT--......
132 ARNHAQRTALGIrnLY.....S.....RNVVLSILTGMIGD---......
133 MAYKFCQAIDEK..LN.....Knea..EQFLDLVSIGNIADS--......
134 VAYHLLWAVYEE..LG.....Rpep..RALLPLATLGTVADV--......
135 VCYFFAREL--N..ER.....N.....KDLAYIAIVGAVGDMQ-......
136 VSYFFAREL--N..EM.....N.....KDLAYIAIVGAVGDMQ-......
137 -------QPKRL..KI.....N.....MIEATALLAGIIVDT--......
138 ---------DET..AI.....D.....KDIATCIYTGLATDTG-......
139 ---------LEI..PI.....T.....DTLATALFYGMYIDT--......
140 ---------MAG..SL.....E.....AAEARALFLGLATDTG-......
141 TAYL-----ATR..LL.....N.....RKTAPLALVGALGDMQ-......
142 LTYLL----ARE..FG.....Y.....RDLSWMGLLAAVGDMQN......
143 TSALVFSQIFQI..QT.....T.....PLEEELIAITLLSD---......
144 VAFKLVEALYNQ..YP.....Tvp6plEDLLDLVAIGLIADL--......
145 VCYFFA---NEL..GR.....N.....RELASVALIGALGDKQR......
146 LNYIFFRAVAGE..E-.....A.....KKYAYIAVLGSVGDY--......
147 ---------NGV..AI.....P.....KEIAGVMLSGLISDT--......
148 ---------LNI..FP.....P.....KNVRIALLCGIVYDT--......
149 TSALVFSQIFQT..QT.....T.....PLEEELIAITLLSD---......
150 TSALVFSQIFQT..QT.....T.....PLEEELIAITLLSD---......
151 VAFYLCYGIHQL..LG.....KekshsSELLCLAGVATIADMMP......
152 TAWKVVTA----..--.....-.....-----------------......
153 ---------LGV..EY.....D.....SNLATLNYLGIATDTG-......
154 ---------LGA..PW.....S.....EAVATPLMLGLNTDTGN......
155 ---------NNV..KI.....E.....KEIAGLMLSAIISD---......
156 ---------HSV..AV.....S.....KEIAGLMLSGLISDT--......
157 ---------LKI..TP.....S.....KILATALFFGIKSE---......
158 ---------LDI..EP.....S.....RNLATALFYGIQSDT--......
159 ----------FN..YS.....D.....ENSAKALLAGIISDTS-......
160 ---------ENA..EI.....T.....RPLALLMISAILSDTV-......
161 TTYLVSKYLRNG..RTlfdy.-endn.SDLLPISIVGAVGDLQ-......
162 ---------TNL..NF.....D.....LKTLNYLLLGITTDSN-......
163 ------------..--.....-.....--WNTWTALGAVGDVG-......
164 ---------KNI..PL.....D.....PTEATLFMIALYDDTGN......
165 ---------AGT..PL.....R.....PSVATAALGGIVYDTGR......
166 VCYLV----ARE..FG.....Y.....YDLSVLAIVGIIGDMQ-......
167 ---------TGV..EI.....P.....KDIAGILLSSILSDT--......
168 VAFYLCYGIHQL..LG.....KekshsSELLCLAGVATIADMMP......
169 ---------LGY..K-.....D.....EDSAKVLLAAIISDT--......
170 YAI------LEP..KN.....T.....TWL--------------......
171 ------------..--.....-.....-----------------......
172 YAIL--------..--.....-.....-----------------......
173 ------------..--.....-.....--WNEWSALGVVGDI--......
174 ---------AKW..TI.....P.....PVAATLLYIGIYTDSN-......
175 ---------AGL..SV.....E.....PQDAKLMLSAILSDT--......
176 AIDLI--GGKKK..EL.....K.....PDLAGLLLSAIISDT--......
177 ---------AKW..KL.....S.....PPAATALYLGIYTDSN-......
178 ---------KGI..DI.....N.....PRDATLLAFGIYEDTGN......