a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1999.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0124 Phospholipase C beta C-terminus, turkey
- gi|4099293|gb|AAD00571.1|_895:1171 (U85712) phospholipase C-beta-1a [Mus musculus] (Mus musculus)
- gi|7110695|ref|NP_032900.1|pPlcb3_940:1200 phospholipase C, beta 3 (Mus musculus)
- gi|1730574|sp|P51432|PIP3_MOUSE 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA 3 (PLC-BETA-3) (PHOSPHOLIPASE C-BETA-3) (Mus musculus)
- gi|1150880|gb|AAA85199.1| (U43144) phospholipase C beta3 [Mus musculus] (Mus musculus)
- gi|226908|prf||1611219A_895:1171 phospholipase C 154 [Bos taurus] (Bos taurus)
- gi|130221|sp|P10894|PIP1_BOVIN_895:1171 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA 1 (PLC-BETA-1) (PHOSPHOLIPASE C-BETA-1) (PLC-I) (PLC-154) (Bos taurus)
- gi|89334|pir||A28822 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) I - bovine (Bos taurus)
- gi|163522|gb|AAA30702.1| (J03137) phospholipase C [Bos taurus] (Bos taurus)
- gi|130223|sp|P10687|PIP1_RAT_895:1170 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA 1 (PLC-BETA-1) (PHOSPHOLIPASE C-BETA-1) (PLC-I) (PLC-154) (Rattus norvegicus)
- gi|91896|pir||A28821 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) I - rat (Rattus norvegicus)
- gi|206218|gb|AAA41885.1| (M20636) phospholipase C-1 [Rattus sp.] (Rattus sp.)
- gi|9368448|emb|CAB98142.1|_895:1171 (AJ278313) phospholipase C-beta-1a [Homo sapiens] (Homo sapiens)
- gi|9438229|gb|AAF86613.1|_890:1166 (AY004175) phospholipase C beta 1 [Homo sapiens] (Homo sapiens)
- gi|3043686|dbj|BAA25507.1|_377:653 (AB011153) KIAA0581 protein [Homo sapiens] (Homo sapiens)
- gi|1082692|pir||S52099_939:1200 phospholipase C beta 3 - human (Homo sapiens)
- gi|829153|emb|CAA85776.1| (Z37544) phospholipase C beta 3 [Homo sapiens] ()
- gi|2134446|pir||S68251_881:1154 phospholipase C, inositol-lipid specific (EC 3.1.4.-) isoform beta - turkey (Meleagris gallopavo)
- gi|1223920|gb|AAC60011.1| (U49431) phospholipase C beta [Meleagris gallopavo] (Meleagris gallopavo)
- gi|1730573|sp|Q01970|PIP3_HUMAN_939:1200 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA 3 (PLC-BETA-3) (PHOSPHOLIPASE C-BETA-3) (Homo sapiens)
- gi|7435175|pir||I38994 phospholipase C-beta-3 - human (Homo sapiens)
- gi|836665|gb|AAA77683.1| (U26425) phospholipase C-beta-3 [Homo sapiens] (Homo sapiens)
- gi|284352|pir||S27002_756:1017 phospholipase C (EC 3.1.4.3), phosphatidylinositol-specific - human (fragment) (Homo sapiens)
- gi|38510|emb|CAA78903.1| (Z16411) phospholipase c [Homo sapiens] (Homo sapiens)
- gi|3688530|emb|CAA09465.1|_884:1149 (AJ011035) phospholipase C beta 2 [Rattus norvegicus] (Rattus norvegicus)
- gi|7296215|gb|AAF51507.1|_987:1267 (AE003589) Plc21C gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|130222|sp|P25455|PIP1_DROME_987:1267 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE CLASSES I AND II (PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C) (Drosophila melanogaster)
- gi|103302|pir||B40879 phospholipase C (EC 3.1.4.3), neuronal, long splice form - fruit fly (Drosophila melanogaster) (Drosophila melanogaster)
- gi|158133|gb|AAA28820.1| (M60453) phospholipase C [Drosophila melanogaster] (Drosophila melanogaster)
- gi|103301|pir||A40879_987:1260 phospholipase C (EC 3.1.4.3), neuronal - fruit fly (Drosophila melanogaster) (Drosophila melanogaster)
- gi|158131|gb|AAA28819.1| (M60452) phospholipase C [Drosophila melanogaster] (Drosophila melanogaster)
- gi|4505867|ref|NP_000924.1|_762:1001 phospholipase C, beta 4 (Homo sapiens)
- gi|762826|gb|AAB02027.1| (L41349) phospholipase C beta 4 [Homo sapiens] (Homo sapiens)
- gi|4758938|ref|NP_004564.1|_879:1147 phospholipase C, beta 2 (Homo sapiens)
- gi|400793|sp|Q00722|PIP2_HUMAN 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA 2 (PLC-BETA-2) (PHOSPHOLIPASE C-BETA-2) (Homo sapiens)
- gi|346297|pir||A43346 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) beta-2 - human (Homo sapiens)
- gi|190040|gb|AAA36453.1| (M95678) phospholipase C-beta-2 [Homo sapiens] (Homo sapiens)
- gi|423977|pir||A45493_921:1183 phospholipase C-beta 3 - rat (fragment) (Rattus norvegicus)
- gi|1079311|pir||A48001_913:1169 phospholipase C (EC 3.1.4.3) beta, oocyte - African clawed frog (Xenopus laevis)
- gi|405590|gb|AAA03065.1| (L20816) phospholipase C beta type [Xenopus laevis] (Xenopus laevis)
- gi|2706546|emb|CAA75861.1| (Y15901) phospholipase C beta type [Xenopus laevis] (Xenopus laevis)
- gi|6807700|emb|CAB70666.1|_635:881 (AL137267) hypothetical protein [Homo sapiens] (Homo sapiens)
- gi|1083573|pir||A53430_895:1141 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) beta-1b - rat (Rattus norvegicus)
- gi|9845289|ref|NP_062651.1|_895:1141 phospholipase C, beta (Mus musculus)
- gi|4099295|gb|AAD00572.1| (U85713) phospholipase C-beta-1b [Mus musculus] (Mus musculus)
- gi|4099297|gb|AAD00573.1| (U85714) phospholipase C-beta-1b' [Mus musculus] (Mus musculus)
- gi|543433|pir||A48047_916:1155 phospholipase C (EC 3.1.4.- ) beta-4 - rat (Rattus norvegicus)
- gi|435757|gb|AAB28484.1| phospholipase C-beta 4, PLC-beta 4 [rats, brain, Peptide, 1176 aa] (Rattus sp.)
- gi|304243|gb|AAA30700.1|_647:886 (L13937) phospholipase C [Bos taurus] (Bos taurus)
- gi|1083064|pir||B38932_763:1002 phospholipase C (EC 3.1.4.3) beta-I form B - bovine (fragment) (Bos taurus)
- gi|304241|gb|AAA30699.1| (L13936) phospholipase C [Bos taurus] (Bos taurus)
- gi|304239|gb|AAC37304.1|_751:990 (L13935) phospholipase C [Bos taurus] (Bos taurus)
- gi|304245|gb|AAA30701.1|_659:898 (L13938) phospholipase C [Bos taurus] (Bos taurus)
- gi|9368450|emb|CAB98143.1|_895:1141 (AJ278314) phospholipase C-beta-1b [Homo sapiens] (Homo sapiens)
- gi|3282557|gb|AAC24984.1|_468:713 (AF027571) phospholipase C-beta 4 isoform [Rattus norvegicus] (Rattus norvegicus)
- gi|7494881|pir||T33283_513:792 hypothetical protein B0348.3 - Caenorhabditis elegans (Caenorhabditis elegans)
- gi|3168960|gb|AAC17811.1| (AF068714) contains similarity to C2 domains (Pfam: C2.hmm, score: 108.46) and to phophatidylinositol-specific phospholipase C, X domains (Pfam: PI-PLC-Y.hmm. score: 204.05) [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|6179894|gb|AAF05701.1|AF179426_1_1121:1419 (AF179426) phospholipase C beta homolog EGL-8 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|7511518|pir||T37264_1120:1406 phospholipase C (EC 3.1.4.-) beta - Caenorhabditis elegans (Caenorhabditis elegans)
- gi|6014683|gb|AAF01458.1|AF188477_1 (AF188477) phospholipase C beta [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|5901838|gb|AAD55427.1|AF181641_1_860:1083 (AF181641) norpA [Drosophila melanogaster] (Drosophila melanogaster)
- gi|1172512|sp|P13217|PIPA_DROME_860:1083 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE (PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C) (Drosophila melanogaster)
- gi|157981|gb|AAA28724.1| (J03138) phospholipase C [Drosophila melanogaster] (Drosophila melanogaster)
- gi|85099|pir||A31225_860:1083 phospholipase C (EC 3.1.4.3) - fruit fly (Drosophila melanogaster) (Drosophila melanogaster)
- gi|4894766|gb|AAD32609.1|AF128539_1_888:1099 (AF128539) phospholipid phospholipase C beta isoform [Homarus americanus] (Homarus americanus)
- gi|8778048|gb|AAF79180.1|_888:1122 (AF258528) phospholipase C [Loligo pealei] (Loligo pealei)
- gi|4521177|dbj|BAA76277.1|_1073:1344 (AB017512) PLC-betaH2 [Hydra magnipapillata] (Hydra magnipapillata)

              10        20        30        40        50        60     
              |         |         |         |         |         |     
   1 NMKEVTQLPEPQTASLAELQQMKLFLKLLKKQEKELKELERKGSKRREELLQKYSVLFLEP....
   2 EDLIQSVLTEVEAQTIEELKQQKSFVKLHKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIq...
   3 DDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALTRRLLDGLAQAr...
   4 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIq...
   5 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIq...
   6 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIq...
   7 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIq...
   8 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIq...
   9 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIq...
  10 DDLIASILSEVAPTPLDELRGHKALVKLRSRQERDLRELRKKHQRKAVTLTRRLLDGLAQAq...
  11 -MKEVTQLPEPQTASLAELQQMKLFLKLLKKQEKELKELERKGSKRREELLQKYSVLFLEPv...
  12 DDLIASILSEVAPTPLDELRGHKALVKLRSRQERDLRELRKKHQRKAVTLTRRLLDGLAQAq...
  13 DDLIASILSEVAPTPLDELRGHKALVKLRSRQERDLRELRKKHQRKAVTLTRRLLDGLAQAq...
  14 -------VAEPQTTSLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELq...
  15 ----------VLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKk...
  16 ----------VLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKk...
  17 ----------VLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKk...
  18 -----------PQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIv...
  19 ---------EPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELg...
  20 DDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALTRRLLDGLAQAr...
  21 DDHIASVLTDIQAPSMEELKSQKSFEKLICRQYRELRQLRRKHLRKVSSLCKEQSTWVTPLq...
  22 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIq...
  23 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKLHHKKTTELIKEHTTKYNEIq...
  24 EDLIQSVLTEVEAQTIEELKQQKSFVKLHKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIq...
  25 -----------PQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIv...
  26 -----------PQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHAKEHSTMQKLHCTQVDKIv...
  27 -----------PQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHAKEHSTMQKLHCTQVDKIv...
  28 -----------PQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHAKEHSTMQKLHCTQVDKIv...
  29 -----------PQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHAKEHSTMQKLHCTQVDKIv...
  30 EDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIq...
  31 -----------PQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIv...
  32 --------FKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQQTNVDKLi...
  33 --------FKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQPARRRNSs...
  34 --------FKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQQTNVDKLi...
  35 EKKEPPLVFEPVT--LESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKL....
  36 EKKEPPLVFEPVT--LESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKL....
  37 EKKEPPLVFEPVT--LESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKL....
  38 -------FVEYEPINLETLRSQKNFLKATKKQQKELESMRKKHMKERLSIQKAQCSAIEKL....
  39 ----------VALPKLDALKSNKAYAKIISKRDKEVDSIKKKNDKAQSNMKTKMKAEEKKMk...
  40 --------------KIDDFKLDKMFLRIAKKNGKEVDILKQNHRKERKLTESFYDEEISKLq...


                   70         80        90       100       110       12
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   5 .40laAL.....DAEMTQKLVD.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
   6 .40laAL.....DAEMTQKLID.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
   7 .40laAL.....DAEMTQKLID.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
   8 .40laAL.....DAEMTQKLID.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
   9 .40laAL.....DAEMTQKLID.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
  10 .22dtKE.....GEDEAKRYQE.FQNRQVQSLLELREAQVDAEAQRRLEHLRQALQRLREVVLDA
  11 .33pvEM.....AEKLDSQVVE.LKERLEMELIHLGEEYHDGIRRRKEQHATEQTAKITELAREK
  12 .22dtKE.....GEDEAKRYQE.FQNRQVQSLLELREAQVDAEAQRRLEHLRQALQRLREVVLDA
  13 .22dtKE.....GEDEAKRYQE.FQNRQVQSLLELREAQVDAEAQRRLEHLRQALQRLREVVLDA
  14 .31prEV.....LEGPDPRVQD.LKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREK
  15 .49aaDA.....GEDLAGGSSS.LDGRtQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKT
  16 .49aaDA.....GEDLAGGSSS.LDGRtQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKT
  17 .42aaDA.....GEDLAGGSSS.LDGRtQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKT
  18 .39iqTL.....TSDHKSKVKE.IVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINA
  19 .36pgEG.....PEGVDGRVRE.LKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREK
  20 .23vkEE.....EKEAARQYRE.FQNRQVQSLLELREAQADAETERRLEHLKQAQQRLREVVLDA
  21 .17vsGA.....DQDAEQKLMD.MQRDQQKRLLELREIQHEQERKLKHSHLLQAVQKLQEVAISY
  22 .40laAL.....DAEMTQKLID.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
  23 .40laAL.....DAEMTQKLID.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
  24 .40laAL.....DAEMTQKLID.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
  25 .39iqTL.....TSDHKSKVKE.IVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINA
  26 .39iqTL.....TSDHKSKVKE.IVAQHTKEWSDMINTHSAEEQEIRDLLLSQQCELLRKLLISA
  27 .39iqTL.....TSDHKSKVKE.IVAQHTKEWSDMINTHSAEEQEIRDLLLSQQCELLRKLLISA
  28 .39iqTL.....TSDHKSKVKE.IVAQHTKEWSDMINTHSAEEQEIRDLLLSQQCELLRKLLISA
  29 .39iqTL.....TSDHKSKVKE.IVAQHTKEWSDMINTHSAEEQEIRDLLLSQQCELLRKLLISA
  30 .40laAL.....DAEMTQKLID.LKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
  31 .39iqTL.....TSDHKSKVKE.IVAQHTKECSEMINTHSAEEQEIRDLHMSQQCELLRKLLINV
  32 .72gsPV.....PQDLvnNDRV.RSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMS
  33 .84gsPV.....PQDLvnNDRV.RSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMS
  34 .72gsPV.....PQDLvnNDRV.RSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMS
  35 .IKGKSKddirnDANIKNSIND.QTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQ
  36 .IKGKSKddirnDANIKNSIND.QTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQ
  37 .IKGKSKddirnDANIKNSIND.QTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQ
  38 .AKGKKDvmd..DPKIKSLVSE.QMKQWSEMMEKHRKEEWEMLKEHLKSQEDILKKLMEEEQAGQ
  39 .20hdQL.....VKENQDKFNQ.LHKENIDKYLATCSEHFNAESEICKKYIDSLNDCLKGVITST
  40 .66tkIW.....KTEKVGKISV.IVEEQKKALKIMIDEHIEKEARIKYSHSIQQIDLIGKLLKTA


      0       130       140           150       160         170       1
     |         |         |             |         |           |        
   1 LKALKESSESNIKDIKKKLEAKRLDRIQVM....MRSTSDKAAQERL..KKEINNSHIQEVVQTI
   2 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--TSKDKSQ..MEEEKTEMIRSYIQEV
   3 HTTQFKRLKELNEREKKELQKILDRKRNNS....ISEA--KTREKHK..KEVELTEINRRHITES
   4 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
   5 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
   6 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
   7 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
   8 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
   9 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
  10 NTTQFKRLKEMNESWPSWPRSVRSSGRGSP....RRSA----GACWA..RCRRgeLTEINRRHIT
  11 QIAELKALKESSESNIKDIKKKLEAKRLDR....IQVMMRSTSDKAA..QERLKKEINNSHIQEV
  12 NTTQFKRLKEMNEREKKELQKILDRKRHNS....ISEA--KMRDKHK..KEAELTEINRRHITES
  13 NTTQFKRLKEMNEREKKELQKILDRKRHNS....ISEA--KMRDKHK..KEAELTEINRRHITES
  14 QAAELKSFKETSETDTKEMKKKLEAKRLER....IQAMTKVTTDKVA..QERLKREINNSHIQEV
  15 SQTGQTKQLKASLDKVTGEVMHQLQEARRN....EVKNLATVHRDRD..ELIRMKREVASSVVER
  16 SQTGQTKQLKASLDKVTGEVMHQLQEARRN....EVKNLATVHRDRD..ELIRMKREVASSVVER
  17 SQTGQTKQLKASLDKVTGEVMHQLQEARRN....EVKNLATVHRDRD..ELIRMKREVASSVVER
  18 HEQQTQQLKLSHDRESKEMRAHQAKISMEN....SKAIsqDKSIKNK..AERERRVRELNSSNTK
  19 QAAELKALKETSENDTKEMKKKLETKRLER....IQGMTKVTTDKMA..QERLKREINNSHIQEV
  20 HTTQFKRLKELNEREKKELQKILDRKRNNS....ISEA--KTREKHK..KEVELTEINRRHITES
  21 HSTQLKKLKEINEKEKKELQKILDRKRHNS....ITEA--KSRERQK..KDVELTEINRRHINES
  22 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
  23 QNNQLKKLKEICEKEKKELKKKMDKKLQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
  24 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--TSKDKSQ..MEEEKTEMIRSYIQEV
  25 HEQQTQQLKLSHDRESKEMRAHQAKISMEN....SKAIsqDKSIKNK..AERERRVRELNSSNTK
  26 HEQQTQQLKLSHDRESKEMRAHQAKISMEN....SKAIsqDKSIKNK..AERERRVRELNSSNTK
  27 HEQQTQQLKLSHDRESKEMRAHQAKISMEN....SKAIsqDKSIKNK..AERERRVRELNSSNTK
  28 HEQQTQQLKLSHDRESKEMRAHQAKISMEN....SKAIsqDKSIKNK..AERERRVRELNSSNTK
  29 HEQQTQQLKLSHDRESKEMRAHQAKISMEN....SKAIsqDKSIKNK..AERERRVRELNSSNTK
  30 QNNQLKKLKEICEKEKKELKKKMDKKRQEK....ITEA--KSKDKSQ..MEEEKTEMIRSYIQEV
  31 HEQQTQQLKVSHDRESKEMRAHQAKICMEN....SKAIsqDKSIKNK..AERERRVRELNSSNTK
  32 EAQKNQMLALKLRLEAEGKDLKQTQTKKSM....EDAKVIqlDKGIK..TKAERDRRVKELNEKN
  33 EAQKNQMLALKLRLEAEGKDLKQTQTKKSM....EDAKVIqlDKGIK..TKAERDRRVKELNEKN
  34 EAQKNQMLALKLRLEAEGKDLKQTQTKKSM....EDAKVIqlDKGIK..TKAERDRRVKELNEKN
  35 IKQLEDRHARDIKDLNAKQAKMSADTAKEVqn..DKTLKTKNEKDRR..LREKRQNNVKRFMEEK
  36 IKQLEDRHARDIKDLNAKQAKMSADTAKEVqn..DKTLKTKNEKDRR..LREKRQNNVKRFMEEK
  37 IKQLEDRHARDIKDLNAKQAKMSADTAKEVqn..DKTLKTKNEKDRR..LREKRQNNVKRFMEEK
  38 IKKMEAKHEQDMKDMKAQQAKAAMETAKDVnq..DKTLKTKADRDRR..LKEKNQNNTKRFIEER
  39 QEDLKKKLQTIHDKEVESMNKELNKKSKEE....QKNLGKETKDKEE..LARKKRELSKKLIDGI
  40 QDNDIKKLAEINEKELSDLTKAQARDSIQS....IKDLekefENSKM..DRINKEKIKRERDKLR


      80       190       200       210       220       230       240  
      |         |         |         |         |         |         |  
   1 KLLTEKTARYQQKLEEKQAENLRAIQEKEGQLQQEAVAEYEEKLKTLTVEVQEMVKNYMKEVFP
   2 VQYIKRLEEAQSKRQEKLVEKHNEIRQQILDEKPKLQTELEQEYQDKFKRLPLEILEFVQEAMK
   3 VNSIRRLEEAQKQRHERLVAGQQQVLQQLEEEEPKLLAQLTQECQEQRERLPQEIRRCLLGETA
   4 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMK
   5 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMK
   6 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQMELEQEYQDKFKRLPLEILEFVQEAMK
   7 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMK
   8 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMK
   9 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMK
  10 ESVNSIRRLEEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQEIRRSLLGE
  11 VQTIKLLTEKTARYQQKLEEKQAENLRAIQEKEGQLQQEAVAEYEEKLKTLTVEVQEMVKNYMK
  12 VNSIRRLEEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQEIRRSLLGEMP
  13 VNSIRRLEEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQEIRRSLLGEMP
  14 VQAVKQMTETLERHQEKLEEKQTACLEQIQAMEKQFQEKALAEYEAKMKGLEAEVKESMRACFK
  15 GVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPH
  16 GVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPH
  17 GVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPH
  18 KFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQA--------------------------
  19 VQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKESVRACLR
  20 VNSIRRLEEAQKQRHERLLAGQQQVLQQLVEEEPKLVAQLTQECQEQRERLPQEIRRCLLGETS
  21 VSSIRRLEEAQKRRQEKLQTAHQETLQRIKDEEPKLQAQLDEACQAEFCQLPQEVRRYLQEDGW
  22 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPK-----------------------------
  23 VQYIKRLEEAQSKRKEKLVEKHKEIRQQILDEKPK-----------------------------
  24 VQYIKRLEEAQSKRQEKLVEKHNEIRQQILDEKPK-----------------------------
  25 KFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQA--------------------------
  26 KFLEERKRLAMKQSKEMDQLKKVQLEHLEFVEKQNEQA--------------------------
  27 KFLEERKRLAMKQSKEMDQLKKVQLEHLEFVEKQNEQA--------------------------
  28 KFLEERKRLAMKQSKEMDQLKKVQLEHLEFVEKQNEQA--------------------------
  29 KFLEERKRLAMKQSKEMDQLKKVQLEHLEFVEKQNEQA--------------------------
  30 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPK-----------------------------
  31 KFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQLLKSCHA--------------------
  32 LKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALD----------------------
  33 LKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVGNYK---------------
  34 LKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVGNYK---------------
  35 KQIGVKQGRAMEKLKLAHSKQIEEFSTDVQKLMDMYKIEEE-----------------------
  36 KQIGVKQGRAMEKLKLAHSKQIEEFSTDVQKLMDMYKIEEE-----------------------
  37 KQIGVKQGRAMEKLKLAHSKQIEEFSTDVQKLMDMYKIEEE-----------------------
  38 KISAMKQGKQKEKLKKVHDQQMTELTKDIQMAIQFY----------------------------
  39 VAERNKLKALKERQEKVLDKNVEELTKEYEKEKANAENKLKEDIDAKLKKV-------------
  40 IEEFGMQRRKLVQNQQKRQEKLIEKHKNENKQFEDHRKEIIQLGYE------------------