(c) 1992-2000 Regents of the University of California, Santa Cruz
Sequence Alignment and Modeling Software System
http://www.cse.ucsc.edu/research/compbio/sam.html

Citations (SAM, SAM-T99, HMMs)

Sequence numbers correspond to the following labels:

    • T0121-cterm MalK, Thermococcus litoralis
    • gi|4581012|gb|AAD24578.1|AF126010_1_231:372 (AF126010) trehalose/maltose transport ATP-hydrolyzing subunit MalK [Thermococcus litoralis] (Thermococcus litoralis)
    • gi|9658383|gb|AAF96842.1|_225:359 (AE004421) maltose/maltodextrin ABC transporter, ATP-binding protein [Vibrio cholerae] (Vibrio cholerae)
    • gi|9106014|gb|AAF83877.1|AE003943_8_226:361 (AE003943) sugar ABC transporter ATP-binding protein [Xylella fastidiosa] (Xylella fastidiosa)
    • gi|9656059|gb|AAF94706.1|_245:374 (AE004233) glycerol-3-phosphate ABC transporter, ATP-binding protein [Vibrio cholerae] (Vibrio cholerae)
    • gi|1842218|gb|AAC34719.1|_226:319 (U49400) orfx protein; similar to MalK and other inner membrane ATP binding transport proteins [Escherichia coli] (Escherichia coli)
    • gi|4106649|emb|CAA21404.1|_15:95 (AL031866) ORF 79, len=113 aa, similar to MalK E. Coli (C- terminal), 33.3% identity in 87 aa overlap, Fasta scores: opt: 164, E(): 2.4e-05, possible frameshift as ORF78 is continuation of ORF 79 [Yersinia pestis] (Yersinia pestis) 
              10        20                30         40             50 
              |         |                 |          |              | 
   1 PANTFVAGFIGSPPMNFLDAIV....TEDG....FVDFGEFRLKLLP.DQFEVLGELG.....YV
   2 PVNTFVAGFIGSPPMNFLDATI....TDDG....FLDFGEFKLKLLQ.DQFEVLEEEN.....MV
   3 PANTFVAGFIGSPPMNFLDAIV....TEDG....FVDFGEFRLKLLP.DQFEVLGELG.....YV
   4 PANTFVAGFIGSPPMNFLDAIV....TEDG....FVDFGEFRLKLLP.DQFEVLGELG.....YV
   5 PLNTFVAGFIGSPPMNFLTATV....SSDG....FLDFGEFRLKLLK.DQFEVLEENN.....LI
   6 PENVFVGGFIGSPSMNFITGKI....EGDY....-FKVGDVTVKVPA.GKLSVLRDKG.....YM
   7 PENVFVGGFIGSPAMNFFKGKL....TDGL....-IKIGSAALTVPE.GKMKVLREKG.....YI
   8 PANKFVAGFIGSPAMNFFDVTI....KDGH....LVSKDGLTIAVTE.GQLKMLESKG.....FK
   9 PANLFVAGFIGSPGMNFLKGII....EQQHgel.FFTNSSIRLHIPE.EKAKRLKEKG.....YA
  10 PANVFVAGFIGSPPMNFVNARVvrg.EGGL....WIQASGFKVKVPK.EF--EDKLAN.....YI
  11 PNSVFVATFIGAPEMNIVEVSV....GDGY....-LEGKGFKIELPQ.DIMELLR--D.....YI
  12 PNSVFVATFIGAPEMNILEVSV....GDGY....-LEGRGFRIELPQ.DLMDLL--KD.....YV
  13 PADRFVAGFIGSPKMNFLPVKV....TATA....-IDQVQVELPMPN.RQQVWLPVESrdv..QV
  14 PADRFVAGFIGSPKMNFLPVKV....TATA....-IDQVQVELPMPN.RQQVWLPVESrdv..QV
  15 PQNRFVAGFIGSPKMNFMSVFI....EG--....-VEKDRVQVQLSN.GTTFWIPVDGttv..TR
  16 PQNRFVAGFIGSPKMNFMSVFI....EG--....-VEKDRVQVQLSN.GTTFWIPVDGttv..TR
  17 PANTFVASFIGSPPMNLMPARIavd.STQH....VELNGGNRISLLP.RA----GTHL.....AP
  18 PADRFVAGFIGSPKMNFLPVKV....TA--....-TAIEQVQVELPN.RQQIWLPVESrgv..QV
  19 PADRFVAGFIGSPKMNFLPVKV....TA--....-TAIEQVQVELPN.RQQIWLPVESrgv..QV
  20 PVNIFVAGFVGSPQMNFLEMEV....RS--....----EGNSVVLQN.GEIKIPAKTD.....PG
  21 PANRFVGEFIGSPPMNFFTLKV....ASAS....VLQHPAFALNLPE.KWHGLV--AP.....YV
  22 PVNMFVAGFIGAPSMNFINCKV....ERNKi...ILSDGNSNTMFDI.PQKFKKVIAN.....IN
  23 PANIFVAGFIGSPSMNFLPATV....AA--....---TNGPLLKTPE.GVALPIDGGPtl...TG
  24 PQNRFVAGFIGSPSMNFLTARV....QNGE....FVIGQSQVAAMGR.LA---ESLRA.....YE
  25 PANTFVAQFIGSPPMNCFPVTIv...KDEH....GIKIDAGLFVLRP.DIPASFLLKN.....YI
  26 PANLFVAGFLGNPAMNMLPGRL....EA--....--VAGGMELHLES.GECVMFVGAIpksv.WF
  27 PANTFVATFIGSPQMNLFSGKV....AGGR....LEALGGIV-----.------EGVG.....LP
  28 PANIFVAGFIGSPQMNFIDGTI....KEEGgky.FACFQSEKIEMPM.DKARLLKEKG.....YI
  29 PKNMFVASFIGNPPTNFLRDFS....VS--....-VENKQTILKRDD.VIIKLPEPVD.....VK
  30 PKYKFVGGFLGNPPMNFVEAKV....EDGK....LVITEKSKLPIPK.QYVEIVKETG.....I-
  31 PMYKFVGGFLGNPPMNFVEARV....EDGK....LLISENNYIPVPK.QYRQIIERLN.....V-
  32 PANLFVAGFIGSPAMNFFQVERlsq.EGKE....KLSLDGVVLPMPD.SV------AK.....NG
  33 PKNTFVATFVGSPQMNLIEGEIikk.DGKV....IFDCGEFSLRLPE.DL--------.....NI
  34 PKHTFVATFIGAPPMNLVECDVesv.GEDL....WISCPGFSRRVPE.EARSVIESKG.....V-
  35 PDNMFVAGFIGSPRMNFLPAVV....IGQA....EGGQVTVALKARP.DTQLTVACATpp...QG
  36 PASTFVASFIGSPAMNFLPASI....KQGQ....LHIAGKHCYLPQF.DA--------.....MS
  37 PASLFVASFIGSPAMNLLTGRVnn..EGTH....FELDGGIELPLNG.GY------RQ.....YA
  38 PANLFVAGFIGSPAMNLVEVPI....TDGG....-VKFGNSVVPVNR.EA---LSAAD.....KG
  39 PASLFVASFIGSPAMNLLTGRVnn..EGTH....FELDGGIELPLNG.GY------RQ.....YA
  40 PVNLFVAGFIGSPVMNFFPAKL....TPNG....-LTLPLGELNLSR.DVQAMIGQHP.....-V
  41 PENVFVAGFIGSPGMNLVTLSI....VDSS....-VLLGDWPIRIPR.EI-------A.....SA
  42 PANLFVAGFLGTPKMGFLKGKV....TR--....-VDGQGCEVQLDA.GTLISLPLSGasl..SV
  43 PRNVFVASFIGTPPANLVSVPL....DSSRrc..LLLPGGGRYCPPR.RIAEKLAAVK.....T-
  44 PANEFVATFLGSPEMNIVNATV....KAGQ....LLWNENPLVKTKF.DL--------.....-P
  45 PGNVFVAGFIGSPAMNLFRLSI....ADST....-VSLGDWQILLPR.AVVG------.....-T
  46 PANLFVAGFIGSPAMNLVEVPI....TDGG....-VKFGNSVVPVNR.DALKAASD--.....KG
  47 PANEFVARFLGTPEMNIIECSV....KNNQ....LFWNNHLLVTESF.KLNV------.....--
  48 PANFFVARFIGSPPMNVIPATI....TATGqqtaVSLAGGKSVTLDV.PT-----NAS.....EN
  49 PANLFVAGFIGSPAMNFFPARL....TAIGl...TLPFGEVTLAPEV.QG---VIAAH.....PK
  50 PNNKFVASFIGSPSINLIDTAI....RKNNerlyVEIAPGVEILIPH.SKQVLL--EG.....YI
  51 PANLFVAGFIGSPKMNLIEGPE....AAKH....-------------.----------.....--
  52 PRNVFVAAFIGTPRINLLRGLV....RAPLdgamTISLGKQFLRLPE.PLSLDHQLLRv....QQ
  53 PYNVFVATFIG--HSNLFYATI....K---....-IEGNDTYLLFRC.GYKLKMDNLLdv...KD
  54 PANMFVSGFIGSPAMNFIRGTI....DGDK....-FVTETLKLTIPE.EKLAVLKTQE.....SL
  55 PANMFVSGFIGSPAMNFIRGTI....DGDK....-FVTETLKLTIPE.EKLAVLKTQE.....SL
  56 PRNRFVAGFIGSPKMNFLEGPE....AAKQ....-------------.----------.....--
  57 PKTRFVASFIG--ETNFLEARV....VNGEv...ITEIGKVRVFGLD.GA--------.....--
  58 PKSEEVARFLG--FENIIEGVA....NGRI....-LKVGDLRIELPR.EV--------.....--
  59 PATYFVATFIG--RSTVLDGRV....SE--....-VLGSGMVRVALE.GGLSIVGTDMeggl.RQ
  60 PNSVFVAGFIGSPKMNFLSGAF....AEPY....-------------.----------.....--
  61 ----------------LLPVKV....TATA....-IDQVQVELPMPN.RQQVWLPVESrdv..QV
  62 PATRFVADFVG--KMSFVGGEI....VS--....-FEDDGMLVRLAD.DVFVRTASVDaa...6a
  63 PVDEGVARFLG--FENIIEGVA....KGNI....-LEANGVKITLPI.SV--------.....--
  64 PRTAFVANFLG--SSNLLAGRV....AE--....-LHGTEATVQTEF.GPLRTLHGAGl....SV
  65 PSPYFVADFLG---ANILEGTV....KG--....-QVNGLTSVNVNS.NI---FRTVD.....CG
  66 PASRFVAEFVG--ARNMLRGRAhitaEGIS....LIECDGISIYSSE.RA--------.....--
  67 PVNPFVADFLG--GTNYLNCNV....TEDN....-------VLCSPI.GEFRLFPEMN.....VQ
  68 PVNTFVATFIGAPAMNLIDAAV....AHGV....-VRAPDLAIPVPD.PA--------.....--
  69 PATPEVAGFIG--RCNLLEGRV....GA--....-TEGGAVQVELGEtGQRLRVAGAC.....SA
  70 PATDFVAKFIG--ETNSFLSTV....VSCT....AIENEEFMLSLQV.PELDRTLTVTadnpiDP
  71 PANKFVAGFIGSPAMNFFNVKV....TGGK....LTNNEGLNMDLPE.GKAKLLKEQG.....YE
  72 PADRFVAGFIGSPKMNFLPVKV....TA--....-TAIEQVQVELPN.RQQVWLPVDSahv..QV
  73 PNSRFTAEFIG--ETNIFDGVV....IEDHadyaVIECEGLENHVRI.DH----GLGG.....PS
  74 PNNLFVAKFIGSPEINFIKKEN....DKSY....-------------.----------.....--
  75 -----------SPAMNFIRGTI....DGDK....-FVTETLKLTIPE.EKLAVLKTQE.....SL
  76 ----------------------....----....-------------.----------.....-S
  77 PANLFVAGFIGSPAMNLVEVPI....TDGG....-VKFGNSVVPVNR.DALKAASD--.....KG
  78 ----------------------....----....-------------.----------.....--
  79 PKNLFVAGFIG--EINMFNATV....IERL....----DEQRVRANV.EGRECNIYVNfav..EP


             60        70               80        90       100         
             |         |                |         |         |         
   1 GREVIFGIRPEDLYDAMFARV.....RVP.GE.NLVRAVVEIVENLGSERIVHLRV.....GGV.
   2 GKEVIFGIRPEDVHDASFTHI.....DVP.EE.NTVKATVDIIENLGGEKIVHLRR.....GNI.
   3 GREVIFGIRPEDLYDAMFARV.....RVP.GE.NLVRAVVEIVENLGSERIVHLRV.....GGV.
   4 GREVIFGIRPEDLYDAMFAQV.....RVP.GE.NLVRAVVEIVENLGSERIVHLRV.....GGV.
   5 GKEVIFGIRPEDIYDASFIRV.....E-E.PE.NIVRAKVDIVENLGGEKIVHLRL.....GDI.
   6 NKEIILGIRPEDIHDE-LLFI.....ESS.PE.TKLTAEIDVAELTGAETVLYSSV.....NGQ.
   7 GKEVIFGIRPEDIHDE-LIVV.....ESY.KN.SSIKAKINVAELLGSEIMIYSQI.....DNQ.
   8 NKNLIFGIRPEDISSS-LLVQ.....ETY.PD.ATVDAEVVVSELLGSETMLYLKL.....GQT.
   9 GEQMIAGVRPEHITQM--TGN.....DQL.FD.SVFQANVEVNENLGSELIVHVMA.....GDE.
  10 DKEIIFGIRPEDIYDK-LFAL.....APS.PE.NTITGVVDVVEPLGSETILHVKV.....GDD.
  11 GKTVLFGIRPEHMTVEGVSELa....HMK.KT.AKLNAKVDFVEALGTDTILHVKF.....GDE.
  12 GKTVLFGIRPEHMTVEGVSELa....HMK.RT.ARLIGKVDFVEALGTDTILHVKF.....GDE.
  13 GANMSLGIRPEHLLPS-----.....-DI.AD.VILEGEVQVVEQLGNETQIHIQI.....PSI.
  14 GANMSLGIRPEHLLPS-----.....-DI.AD.VILEGEVQVVEQLGNETQIHIQI.....PSI.
  15 GERMSLGIRPEHLVEA-----.....-EH.GD.AKIEGKVMIVEKLGNETQVYMNLkg...SDS.
  16 GERMSLGIRPEHLVEA-----.....-EH.GD.AKIEGKVMIVEKLGNETQVYMNLkg...SDS.
  17 GQEVVFGIRPEDVTLD---GV.....EGS.ER.AQIKATVDIVEPLGSESILHATV.....GDH.
  18 GANMSLGIRPEHLLPS-----.....-DI.AD.VTLEGEVQVVEQLGHETQIHIQI.....PAI.
  19 GANMSLGIRPEHLLPS-----.....-DI.AD.VTLEGEVQVVEQLGHETQIHIQI.....PAI.
  20 AKKVILGIRPENVYLE-----.....EKP.NT.LKLEGEVYFAEKLMSDTILHLNV.....GSE.
  21 GRSLILGVRPESFIPS-----.....-TE.GS.NAFPVTVNLVEALGNDTFIYAHLvte..PDL.
  22 GKEMVMGIRPEDIYDA-VFSQ.....NIE.NK.LHVDVYVKVVEKLGSENLIYFDK.....YGT.
  23 RSEVTYGIRPEHLQLG-----.....---.-E.TGIPAEVVVVEPTGSETQLYVTV.....GGR.
  24 GREVFLGIRPEHVGLVGHSDL.....-PQ.GR.NVLRGEVVVVESLGAQTDLIVDV.....AGQ.
  25 GTQVVFGLRPEAITPRTEETL.....ARE.CA.NVIQLKVLAVEALGAETFVYLDA.....GVQ.
  26 GRDVVLGVRPEHIRPA-----.....GLG.EP.VALEATVEALEPVGNEVFLHLRC.....GAL.
  27 DGEVLVGVRPEDVALG-----.....--K.GD.LTFEAYVDFVEDLGSDSVVHLKTq....SGQ.
  28 GKNVIIGVRPEHLDDD-QELG.....EGK.ST.TVIKSKVEVTELMGAESYIYTKL.....GDQ.
  29 LKEVVVGIRPEHCRIS-----.....RER.VE.NSIPGVVYVVEPLGRDIIVNVKTe....KGE.
  30 -TEVIIGFRPHDAEIV-----.....-KG.EG.EGIVGEVYSFEPLGREQIVTVSV.....NDS.
  31 -KDVIIGFRPHDAEVI-----.....-KG.IS.EGIVGEVYSFEPLGREQIVTVSV.....NDS.
  32 DRPLTLGIRPENIYHPQYLPL.....EI-.EP.MELPATVNLVEMMGNELIVYAQTp....AGT.
  33 EGRVILGFRPQHVEVS-----.....EMP.RE.DFIEGKLIGIEKLGVESYAHPAY.....GDV.
  34 -RKIYLGIRPEFISVS-----.....RRE.TE.GSIAGKVYVVEPLGSEYVVNVDI.....GDG.
  35 GDAVTVGVRPEHFLPA-----.....-GS.GD.TQLTAHVDVVEHLGNTSYVYAHTvp...GEQ.
  36 SENITLGIRPEHASLH-----.....PLT.NA.IELKLDIQVVEPLGPNQLVHGKIigl..ESE.
  37 GRKMTLGIRPEHIALS-----.....-SQ.AE.GGVPMVMDTLEILGADNLAHGRW.....GEQ.
  38 DRTVTVGVRPEHFDVVELGGAva...8kd.SA.DAPAGLAVSVNVVEELGADGYVY.....GTAe
  39 GRKMTLGIRPEHIALS-----.....-SQ.AE.GGVPMVMDTLEILGADNLAHGRW.....GEQ.
  40 PDRVIVGVRPEHLTDAKLIDA.....HQH.GTvLTFKVKVDLVESLGADKYIYFTT.....TGCd
  41 ASEVIIGVRPEHFELG-----.....---.-S.LGVEVEIDMVEELGADAYLYGRIag...6kv.
  42 GSAVTLGIRPEHLEIA-----.....-SP.GQ.TTLTVTADVGERLGSDTFCHVITs....NGE.
  43 -NSVILGFRPEVAVLS---ES.....PLG.DY.VSMEAEVYTVETLGRENIVTLLV.....NGS.
  44 DGAIRVGFRYDEVTAP-----.....KND.GS.PVFSGTLISVENLGKHMVGVVES.....NGV.
  45 AAEVIIGVRPEHLELG-----.....---.-G.AGIEMDVDMVEELGADAYLYGRIvs...6ce.
  46 DRTVTVGVRPEHFDVVELNGGaa...8kd.SA.DAPAGLAVSVNVVEETGADGYIY.....GTVe
  47 -EKLLVGFRYEQLVVT-----.....--T.NK.SSLQAKLINIENLGKHLVATISL.....FDT.
  48 GKTASFGVRPEDLRVT-----.....-EA.DD.FLFEGTVSIVEALGEVTLLYIEGlv...ENE.
  49 PENVIVGVRPEHIQDAALIDA.....YQRiRA.LTFQVKVNLVESLGADKYLYFTT.....ESPa
  50 NKPVCFGIRPEHISLA----S.....DDD.DL.NTFEGVLTVVENMGSEKFLYFIV.....GGK.
  51 -GATTIGIRPEHIDLS-----.....--R.EA.GAWEGEVGVSEHLGSDTFLHVHVa....GMP.
  52 GREVIVGLRSEAVRIA-KPSS.....ARP.GE.VLLTGLVEHVEFQGHEVLVHFNT.....GSQp
  53 GDEVVVGIRPEEFFVN-----.....-SE.ND.EGIKAKILSKTFLGKYTNYFLHF.....NDN.
  54 HKPIVMGIRPEDIHPD-----.....-AQ.EE.NNISAKISVAELTGAEFMLYTTV.....G--.
  55 HKPIVMGIRPEDIHPD-----.....-AQ.EE.NNISAKISVAELTGAEFMLYTTV.....G--.
  56 -GAHAIGIRPEHLRIS-----.....--T.TE.GMWPGTVGVSEHLGSDTFLHVTT.....DHG.
  57 -REFCISIRPEKLKIN-----.....-QQ.AE.NTFEAVVEEIGYLGSFLMLKLRA.....GDV.
  58 WGKVRVGIRPEDITIF-MEGV.....KTS.AR.NVFKARVEGIEDLGALVKLTLNL.....GGI.
  59 GERVKVVIRPERVKVG----H.....EYN.GE.NVFEGKVSLAMFLGWRTQLKVEV.....GGQ.
  60 -KADTIGIRAEHLEID-----.....--E.QG.GEWSGTVIHSEMLGSDSYIYLDIg....TGE.
  61 GANMSLGIRPEHLLPS-----.....-DI.AD.VILEGEVQVVEQLGNETQIHIQI.....PSI.
  62 lRLGDEVILAMRPERIALK--.....-KR.GP.RGFGAIPAQIESLAFVGSFHAYM.....VRLd
  63 EGKVRIGVRPEDIILS-TEPV.....KTS.AR.NEFRAEVIGIEELGPLVRVNLKI.....GGI.
  64 GQEVTLSIRPEKLRME---RD.....DET.EG.NEVRARVDDIVYTGAENQYLLEA.....HGQ.
  65 EGSVILSIRPENIMIA-ADPF.....MAS.AQ.NIFKGTVEDIIETSRIVYVNLRI.....GDI.
  66 TGDVSATIRPEDITVS-WQRT.....DSS.AL.NQLEGRVLAVRDAGSVQQLEVRC.....GGE.
  67 KGRYRWLLRPEQIILK-----.....---.PN.ELGLGKVVGKLFLGLYYRYQVEI.....KGI.
  68 AERVLVGVRPESWDVA-----.....SIG.TP.GSLTVHVELVEELGFESFVYATP.....VDQr
  69 GSSATVGLRSERITLTDRADA.....PHD.GAvNVLRARIEQCSYTGARFEYELSI.....GDV.
  70 GRRVCFTVRPEKIHISLEEPG.....TTS.APlNVFRGFVEEPVYAGFQSKFFVQLe....SGA.
  71 GKEVILGIRPEDIQ-------.....---.--.-----------------------.....---.
  72 GANMSLGIRPEHLLPS-----.....---.--.-----------------------.....---.
  73 EQDLWVSIRPEDIDLYKEKPE.....YLG.DY.NWAKGTVKEIAYLGSFAIYHIKL.....GNGr
  74 ------YIRHNKIKVK-----.....---.PN.LNGKYQIIDKKSFGDKVHYLINF.....NKD.
  75 HKPIVMGIRPEDIHPD-----.....-AQ.EE.NNISAKISVAELTGAEFMLYTTV.....G--.
  76 GEHVKVGIRPEHLRLC-----.....-DQ.AE.AHLIGQIQHIEHLGEAAYFYVSV.....NNF.
  77 DRTVTVGVRPEHFDVV-----.....---.--.-----------------------.....---.
  78 ------GIRPEMFKVC-----.....-PE.AE.ALFNEQIPVAEALGADTFVFFDI.....ASPp
  79 GQKLHVLLRPEDLRVE-----.....EIN.DD.NHAEGLIGYVR------------.....---.


                110            120       130       140  
                 |              |         |         |  
   1 ....T..FVGAFRS.....ESRVREGVEVDVVFDMKKIHIFDKTTGKAIF
   2 ....S..FTAKFPK.....ESKVREGDEVSVVFDMKKIHIFRKDTEKAIF
   3 ....T..FVGAFRS.....ESRVREGVEVDVVFDMKKIHIFDKTTGKAIF
   4 ....T..FVGSFRS.....ESRVREGVEVDVVFDMKKIHIFDKTTGKAIF
   5 ....I..FTAKFPQ.....ESVVEEGQEAEVFFDMKKAHVFNKTNERAIF
   6 ....A..FVARIDS.....RTDIEGGQSLDLAFDMNKSHFFDAETELRI-
   7 ....D..FIARIDA.....RLDIQSGDELTVAFDMNKGHFFDSETEVR--
   8 ....E..FAARVDA.....RDFHEPGEKVSLTFNVAKGHFFDAETEAAI-
   9 ....R..LKVRLDG.....NTRIDAGDSIQLSVKMDHVVFFDAETEEAVY
  10 ....L..IVASVNP.....RTQAKEEQKIDLVLDMTRMHAFDKETEKAI-
  11 ....L..VKVKLPG.....HIPIEVGKEVTIVIDLDMMHVFDKDTEKAI-
  12 ....L..VKVKLPG.....HIPIEPGREVKVIMDLDMIHVFDKDTEKAI-
  13 ....RqnLVYRQND.....VVLVEEGATFAIGLPPERCHLFREDGTA---
  14 ....RqnLVYRQND.....VVLVEEGATFAIGLPPERCHLFREDGTA---
  15 ....D..VIYRQPD.....TLDVETGDTLTIGIPAHRCHLFHSDGRA---
  16 ....D..VIYRQPD.....TLDVETGDTLTIGIPAHRCHLFHSDGRA---
  17 ....S..LVVKVGG.....LNEVHPGDPVTLHVDLTRVHLFDAQSQASIY
  18 ....RqnLVYRQND.....VVLVEEGATFAIGLPPERCHLFREDGSA---
  19 ....RqnLVYRQND.....VVLVEEGATFAIGLPPERCHLFREDGSA---
  20 ....K..IVAKIPG.....DVDFRSGEKITFFLDVEKIHLFHPETGERI-
  21 ....T..IQARIAP.....DHPLQVGEQLWLTINPEKIHLFDAKTEQAI-
  22 ....T..ITARVNS.....QSRIVSGEYAKVAFNIDKIYLFDKETGIAIY
  23 ....E..VVAVLRD.....RVDVRPGEKIWLTPRKGCAHLFDPNTGARI-
  24 ....Q..VTAKVEG.....MAPVQPGDQVELLIDQTRLHAFDTETELAI-
  25 ....P..IVARCNH.....TLTAHEGTLLTLALDLSKALYFDAETGHA--
  26 ....A..LTLRVPP.....QELPGIGESLPLAVQPDRLHVFDAVSGECL-
  27 ....V..IVAKLSG.....GEPPSPGSRVIAGVSREKIHIFDKESGKAI-
  28 ....N..ITVRVNG.....STKLQNGQEAKFYVDANKIHIFDKETE----
  29 ....I..IKVFGDT.....GKAPQPGENVFLVPDLRKIHLFNPETEETI-
  30 ....I..VKVFAPE.....GEHFSFGEKVTIKVKEELLVLFDKKTEKAL-
  31 ....I..VKVFAPE.....GEHFNFGEKVTIKLKEGSVVLFDKKSEKAL-
  32 ....E..FVARIDP.....RVNIKQKDSVKFVVDTQRFYYFDREMETAIF
  33 ....E..IIIRVPE.....ELKIKE-RKIYWRPSLTRIYLFDPRTGELIY
  34 ....Ii.IKAKVLGl....REKMTPGDKVYLKLDWSKVKIFDYRTGEA--
  35 ....I..IIEQEER.....RHGGRYGDEIAVGISAKTSFLFDASG-----
  36 ....Q..DFIAVTA.....EIPLDVHQTLPIWVALEQLHLFDQQGKRF--
  37 ....K..LVVRLAH.....QERPTAGSTLWLHLAENQLHLFDGETGQ---
  38 v...G..GEvkDLV.....VRVNGRQVPEKGSTLHVVPRPGETHVFSTST
  39 ....K..LVVRLAH.....QERPTAGSTLWLHLAENQLHLFDGETGQ---
  40 ....1..9enQFVA.....RVSAESKMAIGESIELAFGTAKIAVFDADSG
  41 ....T..DQLVVAR.....VDGRNPPAKGSRVRLYTEPGNVHFFGVDG--
  42 ....P..LTMRIRG.....DMASQYGETLHLHLDPAHCHLFDTD------
  43 ....Q..VKVIVPP.....VVEPRPGSRIFINIEEDKVMYFDPETEI---
  44 ....Q..LNVRLEL.....SHQFEVGNAVKFTIKPNGLHFFDPQTTQR--
  45 ....M..DQSIVAR.....VDGRGPPERGSRVRLCPTPGHLHFFAVDGR-
  46 vgg.E..TKDLVVR.....VSSRAVPEKGATVHVVPRPGEIHVFSSSTGE
  47 ....T..LSMRLEL.....NSHLKVGDSLNFIIKANNLHFFDIDTKQRI-
  48 ....P..IIAKMPG.....IARVGRGDKVRFTADKAKLHLFDTNG-----
  49 ....2..2enQFVA.....RVPAESKVAIGQSVELAFDTARLAVFDADSG
  50 ....E..LIARVDTqd...INPFHIGKTLRFNLNTAFCHVFDF-------
  51 ....T..LTVRTGG.....EFGVHHGDRVWLTPQADKIHRFGADG-----
  52 ....6..4pgDLIV.....RTTPDIDLRHGMQVPLLVDLAHLFVFDQHGD
  53 ....E..VVPDQPSi....10ytDRMYEKDEVITLKPNANKINVFTPDME
  54 ....-..-------.....-------------------------------
  55 ....-..-------.....-------------------------------
  56 ....L..INVRAGG.....EVGLHHGDRVFLSPDMGQLHRFDAQGG----
  57 ....V..VKAFAPP.....QENVREGERVIVGWDSRD-------------
  58 ....I..LRAFITRssli.ELGIREGEEVYASFKASAIHVF---------
  59 ....E..ITIYSDP.....RRAPLPGQPVRFYIDPEEAKVYR--------
  60 ....P..VIVRESG.....IAKHQPGQTIRISPAAGQVHRFDAGG-----
  61 ....RqnLVYRQND.....VVLVEEGATFAIGLPPERCHLFREDGTA---
  62 lpgsP..LVEVQVV.....TGSEVNFRAGDTVDLVPDPQAVSFFSKE---
  63 ....T..LKAFITRssli.ELGISEGREVYVSFKTSAIKV----------
  64 ....R..LVAFQLNadigaDEDFDYDEEVALYLPPASLV-----------
  65 ....V..LTSAVTPgavt.ELGIRTGEEFQVLIKATNVRIIG--------
  66 ....T..LTVHMTGksln.DMGITTGSRVWIEFKASAVH-----------
  67 ....E..IVTYQSQ.....ELKI--GEQVEVGFQVREFIL----------
  68 g...8apRIVFRTD.....RRTAVRVGESLAIVPHSQEVRLFNSRTET--
  69 ....R..VHAESP-.....--VRHTDGEINLIIRPDDCLLFP--------
  70 ....I..IQVFQQH.....QKYLDTGPEIA--------------------
  71 ....-..-------.....-------------------------------
  72 ....-..-------.....-------------------------------
  73 v...8vpAPYWYVR.....NITPPTWDETVYISWPE--------------
  74 ....I..KWNLVLN.....DNSLQVNDLIDLKYNQSDVLVFNKNGNR---
  75 ....-..-------.....-------------------------------
  76 ....Dp.MLVRHSE.....DQKLALGDDVGLMIPAHHAHLFDNK------
  77 ....-..-------.....-------------------------------
  78 ....1..9knRLVA.....RIPPALTPRPNQVLPLTVDLEKLHWFDPVTG
  79 ....-..-------.....-------------------------------