a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1999.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0117 Deoxyribonucleoside kinase, Drosophila melanogaster
- gi|4741228|emb|CAB41881.1|_4:249 (Y18048) deoxynucleoside kinase [Drosophila melanogaster] (Drosophila melanogaster)
- gi|5924308|gb|AAD56545.1|AF185268_1 (AF185268) deoxyribonucleoside kinase [Drosophila melanogaster] (Drosophila melanogaster)
- gi|7025919|gb|AAD47355.2|AF045610_1 (AF045610) deoxyribonucleoside kinase [Drosophila melanogaster] (Drosophila melanogaster)
- gi|7300459|gb|AAF55615.1| (AE003724) dnk gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|6502515|gb|AAF14342.1|U90524_1_19:270 (U90524) deoxyguanosine kinase [Mus musculus] (Mus musculus)
- gi|2497574|sp|O00142|KITM_HUMAN_3:232 THYMIDINE KINASE 2, MITOCHONDRIAL (Homo sapiens)
- gi|1905969|gb|AAC51167.1| (U77088) thymidine kinase 2 [Homo sapiens] (Homo sapiens)
- gi|4456608|emb|CAA71523.2|_5:230 (Y10498) thymidine kinase [Homo sapiens] (Homo sapiens)
- gi|2833282|sp|Q16854|DGK_HUMAN_21:270 DEOXYGUANOSINE KINASE PRECURSOR (DGUOK) (Homo sapiens)
- gi|7434491|pir||JC6142 deoxyguanosine kinase (EC 2.7.1.113) precursor - human (Homo sapiens)
- gi|1477482|gb|AAC50624.1| (U41668) deoxyguanosine kinase [Homo sapiens] (Homo sapiens)
- gi|7304999|ref|NP_038792.1|_20:270 deoxyguanosine kinase (Mus musculus)
- gi|4877287|emb|CAB43121.1| (AJ133749) deoxyguanosine kinase 1 [Mus musculus] (Mus musculus)
- gi|1905974|gb|AAC51168.1|_2:222 (U80628) thymidine kinase 2 isoform B [Homo sapiens] (Homo sapiens)
- gi|4503319|ref|NP_001920.1|_4:253 deoxyguanosine kinase (Homo sapiens)
- gi|1480198|emb|CAA66054.1| (X97386) deoxyguanosine kinase [Homo sapiens] (Homo sapiens)
- gi|7434490|pir||S71315_4:253 deoxyguanosine kinase (EC 2.7.1.113) precursor - human (Homo sapiens)
- gi|4877289|emb|CAB43122.1|_2:239 (AJ133750) deoxyguanosine kinase 2 [Mus musculus] (Mus musculus)
- gi|6424683|gb|AAF08104.1|AF105217_1_38:269 (AF105217) thymidine kinase 2 [Mus musculus] (Mus musculus)
- gi|4503269|ref|NP_000779.1|_3:257 deoxycytidine kinase (Homo sapiens)
- gi|118447|sp|P27707|DCK_HUMAN DEOXYCYTIDINE KINASE (DCK) (Homo sapiens)
- gi|105829|pir||A38585 deoxycytidine kinase (EC 2.7.1.74) - human (Homo sapiens)
- gi|181510|gb|AAA35752.1| (M60527) deoxycytidine kinase [Homo sapiens] (Homo sapiens)
- gi|6681141|ref|NP_031858.1|_3:257 deoxycytidine kinase (Mus musculus)
- gi|1169273|sp|P43346|DCK_MOUSE DEOXYCYTIDINE KINASE (DCK) (Mus musculus)
- gi|1083283|pir||A55122 deoxycytidine kinase (EC 2.7.1.74) - mouse (Mus musculus)
- gi|456677|emb|CAA54787.1| (X77731) deoxycytidine kinase [Mus musculus] (Mus musculus)
- gi|1352235|sp|P48769|DCK_RAT_3:257 DEOXYCYTIDINE KINASE (DCK) (Rattus norvegicus)
- gi|508570|gb|AAA65098.1| (L33894) deoxycytidine kinase [Rattus norvegicus] (Rattus norvegicus)
- gi|4494925|gb|AAD21347.1|_211:445 (AF083501) thymidine kinase [Macaca mulatta rhadinovirus 17577] (Macaca mulatta rhadinovirus 17577)
- gi|7330010|gb|AAF59999.1|AF210726_20_211:445 (AF210726) thymidine kinase [Macaca mulatta rhadinovirus 26-95] (Macaca mulatta rhadinovirus 26-95)
- gi|4019247|gb|AAC95545.1|_190:439 (AF083424) thymidine kinase [Ateline herpesvirus 3] (Ateline herpesvirus 3)
- gi|7271649|gb|AAF44495.1|AF198100_142_9:230 (AF198100) ORF FPV151 Deoxycytidine kinase [Fowlpox virus] (Fowlpox virus)
- gi|2370245|emb|CAA73635.1|_190:438 (Y13183) thymidine kinase [Saimiriine herpesvirus 2] (Saimiriine herpesvirus 2)
- gi|125448|sp|P21293|KITH_HSVSA_190:438 THYMIDINE KINASE (Herpesvirus saimiri (STRAIN 11))
- gi|66706|pir||KIBEHS thymidine kinase (EC 2.7.1.21) - saimiriine herpesvirus 1 (strain 11[Onc]) (Saimiriine herpesvirus 1)
- gi|60341|emb|CAA45643.1| (X64346) thymidine kinase [Saimiriine herpesvirus 2] (Saimiriine herpesvirus 2)
- gi|221856|dbj|BAA00432.1| (D00543) thymidine kinase [Saimiriine herpesvirus 2] (Saimiriine herpesvirus 2)
- gi|1246355|gb|AAA93507.1|_266:498 (L37432) (thymidine kinase):(phleomycin/zeocin binding protein) fusion protein [Cloning vector pZEO-SG1] (Cloning vector pZEO-SG1)
- gi|118822|sp|P14344|KITH_VZVW_1:217 THYMIDINE KINASE (Human herpesvirus 3)
- gi|66708|pir||KIBEEL thymidine kinase (EC 2.7.1.21) - human herpesvirus 3 (strains Ellen, Oka, ppIIa, and 5-1-1) (Human herpesvirus 3)
- gi|330327|gb|AAA45865.1| (M36160) thymidine kinase [Human herpesvirus 3] (Human herpesvirus 3)
- gi|5926722|dbj|BAA23727.2| (AB009252) thymidine kinase [Human herpesvirus 3] (Human herpesvirus 3)
- gi|5926724|dbj|BAA23728.2| (AB009253) thymidine kinase [Human herpesvirus 3] (Human herpesvirus 3)
- gi|118821|sp|P14343|KITH_VZVG_1:217 THYMIDINE KINASE (Human herpesvirus 3 (acyclovir-resistant strain GK))
- gi|66711|pir||KIBEGK thymidine kinase (EC 2.7.1.21) - human herpesvirus 3 (strain GK) (Human herpesvirus 3)
- gi|118820|sp|P09250|KITH_VZVD_1:217 THYMIDINE KINASE (Human herpesvirus 3 (strain Dumas))
- gi|66707|pir||KIBE36 thymidine kinase (EC 2.7.1.21) - human herpesvirus 3 (Human herpesvirus 3)
- gi|60025|emb|CAA27919.1| (X04370) ORF36 (AA1-341) [Human herpesvirus 3] (Human herpesvirus 3)
- gi|263540|gb|AAB24914.1| thymidine kinase, TK [varicella zoster virus VZV, Peptide, 341 aa] (Human herpesvirus 3)
- gi|118818|sp|P14341|KITH_VZV4_1:217 THYMIDINE KINASE (Human herpesvirus 3 (acyclovir-resistant strain 40A2))
- gi|66710|pir||KIBE40 thymidine kinase (EC 2.7.1.21) - human herpesvirus 3 (strain 40a2) (Human herpesvirus 3)
- gi|1246358|gb|AAA93509.1|_3:218 (L37440) thymidine kinase:phleomycin/zeocin resistance fusion protein [Cloning vector pZEO-SG2] (Cloning vector pZEO-SG2)
- gi|5732886|gb|AAD49322.1|_1:217 (AF162440) thymidine kinase [Human herpesvirus 3] (Human herpesvirus 3)
- gi|1072623|pir||C56604_107:338 thymidine kinase (EC 2.7.1.21) - bovine herpesvirus 4 (Bovine herpesvirus 4)
- gi|261090|gb|AAB24379.1| (S49773) thymidine kinase, TK [bovine herpesvirus type 4 BHV-4, Peptide, 445 aa] [Bovine herpesvirus 4] (Bovine herpesvirus 4)
- gi|449384|prf||1919221C thymidine kinase [Bovine herpesvirus 4] (Bovine herpesvirus 4)
- gi|1246776|emb|CAA63755.1|_308:540 (X93468) thymidine kinase [murine herpesvirus 68] (murine herpesvirus 68)
- gi|2317936|gb|AAB66394.1|_308:540 (U97553) thymidine kinase [murid herpesvirus 4] (murid herpesvirus 4)
- gi|6625585|gb|AAF19286.1|AF105037_18 (AF105037) 21 [murid herpesvirus 4] (murid herpesvirus 4)
- gi|118819|sp|P14342|KITH_VZV7_1:217 THYMIDINE KINASE (Human herpesvirus 3 (acyclovir-resistant strain 7-1-3))
- gi|66709|pir||KIBE73 thymidine kinase (EC 2.7.1.21) - human herpesvirus 3 (strain 7-1-3) (Human herpesvirus 3)
- gi|5732882|gb|AAD49321.1|_1:217 (AF162437) thymidine kinase [Human herpesvirus 3] (Human herpesvirus 3)
- gi|1360832|pir||S55615_275:516 thymidine kinase (EC 2.7.1.21) - equine herpesvirus 2 (Equine herpesvirus 2)
- gi|695193|gb|AAC13808.1| (U20824) thymidine kinase [Equine herpesvirus 2] (Equine herpesvirus 2)
- gi|586859|sp|P37529|YAAF_BACSU_3:213 HYPOTHETICAL 25.4 KD PROTEIN IN SERS-DNAZ INTERGENIC REGION (Bacillus subtilis)
- gi|2127021|pir||S66044 deoxypurine kinase (EC 2.7.1.-) yaaF - Bacillus subtilis (Bacillus subtilis)
- gi|467404|dbj|BAA05250.1| (D26185) unknown [Bacillus subtilis] (Bacillus subtilis)
- gi|2632281|emb|CAB11790.1| (Z99104) similar to deoxypurine kinase subunit [Bacillus subtilis] (Bacillus subtilis)
- gi|7444320|pir||T03116_219:438 thymidine kinase (EC 2.7.1.21) - alcelaphine herpesvirus 1 (Alcelaphine herpesvirus 1)
- gi|2337984|gb|AAC58068.1| (AF005370) thymidine kinase [Alcelaphine herpesvirus 1] (Alcelaphine herpesvirus 1)
- gi|462450|sp|P33802|KITH_HSVBM_217:436 THYMIDINE KINASE (Bovine herpesvirus 3 (strain WC11))
- gi|320275|pir||A60030 thymidine kinase (EC 2.7.1.21), BXLF1 homolog - alcelaphine herpesvirus 1 (strain WC11) (Alcelaphine herpesvirus 1)
- gi|227948|prf||1714185A gene A [Bovine herpesvirus 3] (Bovine herpesvirus 3)
- gi|1136820|gb|AAB08396.1|_235:468 (U40377) thymidine kinase [Kaposi's sarcoma-associated herpesvirus] (Kaposi's sarcoma-associated herpesvirus)
- gi|1718273|gb|AAC57102.1| (U75698) ORF 21; thymidine kinase TK homolog; EBV BXLF1 homolog [Kaposi's sarcoma-associated herpesvirus] (Kaposi's sarcoma-associated herpesvirus)
- gi|2246497|gb|AAB62622.1| (U93872) ORF 21, thymidine kinase (TK) homolog [Kaposi's sarcoma-associated herpesvirus] (Kaposi's sarcoma-associated herpesvirus)
- gi|66705|pir||KIBETE_266:498 thymidine kinase (EC 2.7.1.21) BXLF1 - human herpesvirus 4 (strain B95-8) (Human herpesvirus 4)
- gi|1170666|sp|P03177|KITH_EBV_266:498 THYMIDINE KINASE (Human herpesvirus 4 (strain B95-8))
- gi|1334907|emb|CAA24799.1| (V01555) BXLF1 early reading frame, thymidine kinase (Littler et al, 1986). Weak homology to RF 36 VZV and HSV thymidine kinase. 4.0kb early RNA presumably encodes the TK. Also a 2.2kb late RNA here. [Human herpesvirus 4] (Human herpesvirus 4)
- gi|140631|sp|P21974|YF26_FOWP1_10:216 HYPOTHETICAL 25.9 KD PROTEIN (Fowlpox virus (strain FP-1))
- gi|93206|pir||D35216 FP26 protein - fowlpox virus (strain FP-1) (Fowlpox virus)
- gi|61227|emb|CAA35067.1| (X17202) ORF FP25.9 [Fowlpox virus] (Fowlpox virus)
- gi|7271557|gb|AAF44403.1|AF198100_50 (AF198100) ORF FPV059 Deoxycytidine kinase [Fowlpox virus] (Fowlpox virus)
- gi|7428050|pir||G70129_5:198 deoxyguanosine/deoxyadenosine kinase I (EC 2.7.1.-) subunit 2 dck homolog - Lyme disease spirochete (Borrelia burgdorferi)
- gi|2688138|gb|AAC66630.1| (AE001134) deoxyguanosine/deoxyadenosine kinase(I) subunit 2 (dck) [Borrelia burgdorferi] (Borrelia burgdorferi)
- gi|125445|sp|P28855|KITH_HSVI1_6:210 THYMIDINE KINASE (Ictalurid herpesvirus 1)
- gi|66704|pir||KIBEIC thymidine kinase (EC 2.7.1.21) - ictalurid herpesvirus 1 (Ictalurid herpesvirus 1)
- gi|331215|gb|AAA88108.1| (M75136) thymidine kinase [Ictalurid herpesvirus 1] (Ictalurid herpesvirus 1)
- gi|331292|gb|AAA88186.1| (M75136) thymidine kinase [Ictalurid herpesvirus 1] (Ictalurid herpesvirus 1)
- gi|7471796|pir||F75535_2:195 deoxyguanosine kinase/deoxyadenosine kinase subunit - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6457974|gb|AAF09882.1|AE001891_1 (AE001891) deoxyguanosine kinase/deoxyadenosine kinase subunit [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|3023658|sp|Q59483|DGK1_LACAC_1:211 DEOXYADENOSINE KINASE (DADO KINASE) (DAK) (DEOXYNUCLEOSIDE KINASE COMPLEX I S-COMPONENT) (Lactobacillus acidophilus)
- gi|1361409|pir||A56168 deoxyadenosine kinase (EC 2.7.1.76) - Lactobacillus acidophilus (strain R-26) (Lactobacillus acidophilus)
- gi|403983|gb|AAB09750.1| (U01881) deoxyguanosine kinase/deoxyadenosine kinase(I) subunit [Lactobacillus acidophilus] (Lactobacillus acidophilus)
- gi|687841|gb|AAA62532.1|_54:304 (U21320) similar to NADH dehydrogenase [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|464254|sp|P34942|NUDM_BOVIN_28:262 NADH-UBIQUINONE OXIDOREDUCTASE 42 KDA SUBUNIT, MITOCHONDRIAL PRECURSOR (COMPLEX I-42KD) (CI-42KD) (Bos taurus)
- gi|89675|pir||S17677 NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) 42K chain precursor - bovine (Bos taurus)
- gi|230|emb|CAA42054.1| (X59419) NADH dehydrogenase (ubiquinone) 39 kDa subunit [Bos taurus] (Bos taurus)
- gi|833830|gb|AAB04138.1|_4:224 (U25806) thymidine kinase [Cercopithecine herpesvirus 9] (Cercopithecine herpesvirus 9)
- gi|4033719|gb|AAC97156.1|_1:204 (U49397) unknown [Streptococcus pyogenes] (Streptococcus pyogenes)
- gi|7461161|pir||T03086_1:192 probable thymidine kinase (EC 2.7.1.21) - Chilo iridescent virus (Chilo iridescent virus)
- gi|2738433|gb|AAB94460.1| (AF003534) putative thymidine kinase [Chilo iridescent virus] (Chilo iridescent virus)
- gi|4758768|ref|NP_004535.1|_50:274 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD) (Homo sapiens)
- gi|6093592|sp|O95299|NUDM_HUMAN NADH-UBIQUINONE OXIDOREDUCTASE 42 KDA SUBUNIT, MITOCHONDRIAL PRECURSOR (COMPLEX I-42KD) (CI-42KD) (Homo sapiens)
- gi|7513179|pir||JE0385 NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) chain NDUFA10 - human (Homo sapiens)
- gi|4191348|gb|AAD09755.1| (AF087661) NADH-ubiquinone oxidoreductase 42 kDa subunit [Homo sapiens] (Homo sapiens)
- gi|3023659|sp|Q59484|DGK2_LACAC_1:213 DEOXYGUANOSINE KINASE (DGUO KINASE) (DGK) (DEOXYNUCLEOSIDE KINASE COMPLEX I F-COMPONENT) (Lactobacillus acidophilus)
- gi|1361410|pir||B56168 deoxyguanosine kinase (EC 2.7.1.113) - Lactobacillus acidophilus (Lactobacillus acidophilus)
- gi|403984|gb|AAB09751.1| (U01881) deoxyguanosine kinase/deoxyadenosine kinase(I) subunit [Lactobacillus acidophilus] (Lactobacillus acidophilus)
- gi|586860|sp|P37530|YAAG_BACSU_5:202 HYPOTHETICAL 24.1 KD PROTEIN IN SERS-DNAZ INTERGENIC REGION (Bacillus subtilis)
- gi|2127022|pir||S66045 deoxypurine kinase (EC 2.7.1.-) yaaG - Bacillus subtilis (Bacillus subtilis)
- gi|467405|dbj|BAA05251.1| (D26185) unknown [Bacillus subtilis] (Bacillus subtilis)
- gi|2632282|emb|CAB11791.1| (Z99104) similar to deoxypurine kinase subunit [Bacillus subtilis] (Bacillus subtilis)
- gi|7471797|pir||G75535_1:195 deoxyguanosine kinase/deoxyadenosine kinase subunit - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6457975|gb|AAF09883.1|AE001891_2 (AE001891) deoxyguanosine kinase/deoxyadenosine kinase subunit [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|7461850|pir||T17919_1:186 kinase-like protein A416R - Chlorella virus PBCV-1 (Paramecium bursaria Chlorella virus 1)
- gi|1620088|gb|AAC96784.1| (U42580) contains ATP/GTP-binding site motif A; similar to Bacillus subtilus 24.1 kDa protein, corresponds to Swiss-Prot Accession Number P37530 [Paramecium bursaria Chlorella virus 1] (Paramecium bursaria Chlorella virus 1)
- gi|1723139|sp|P47510|Y268_MYCGE_14:216 HYPOTHETICAL PROTEIN MG268 (Mycoplasma genitalium)
- gi|1361480|pir||F64229 deoxyguanosine/deoxyadenosine kinase(I) chain 2 homolog - Mycoplasma genitalium (Mycoplasma genitalium)
- gi|3844864|gb|AAC71490.1| (U39706) conserved hypothetical protein [Mycoplasma genitalium] (Mycoplasma genitalium)
- gi|7469438|pir||S76121_24:234 hypothetical protein - Synechocystis sp. (strain PCC 6803) (Synechocystis sp.)
- gi|1001473|dbj|BAA10099.1| (D63999) hypothetical protein [Synechocystis sp.] (Synechocystis sp.)
- gi|2496356|sp|P75396|Y268_MYCPN_16:219 HYPOTHETICAL PROTEIN MG268 HOMOLOG (Mycoplasma pneumoniae)
- gi|2146291|pir||S73777 hypothetical protein yaaF - Mycoplasma pneumoniae (strain ATCC 29342) (Mycoplasma pneumoniae)
- gi|1674139|gb|AAB96099.1| (AE000044) Mycoplasma pneumoniae, hypothetical protein (yaaF) homolog; similar to Swiss-Prot Accession Number P37529, from B. subtilis (Mycoplasma pneumoniae)
- gi|8247943|sp|Q55593|KTHY_SYNY3_2:210 THYMIDYLATE KINASE (DTMP KINASE) (Synechocystis PCC6803)
- gi|6899038|gb|AAF30491.1|AE002108_4_21:225 (AE002108) deoxyguanosine kinase [Ureaplasma urealyticum] (Ureaplasma urealyticum)
- gi|3769437|gb|AAC64514.1|_4:216 (AF059316) thymidine kinase [macropodid herpesvirus type 2] (macropodid herpesvirus type 2)
- gi|125440|sp|P22649|KITH_HSVBH_5:212 THYMIDINE KINASE (Bovine herpesvirus type 2 (strain BHM-1))
- gi|66696|pir||KIBEB2 thymidine kinase (EC 2.7.1.21) - bovine herpesvirus 2 (Bovine herpesvirus 2)
- gi|221805|dbj|BAA00425.1| (D00537) thymidine kinase [Bovine herpesvirus 2] (Bovine herpesvirus 2)
- gi|1074411|pir||A64153_11:230 dTMP kinase (EC 2.7.4.9) - Haemophilus influenzae (strain Rd KW20) (Haemophilus influenzae)
- gi|7493480|pir||T41553_7:201 thymidylate kinase - fission yeast (Schizosaccharomyces pombe) (Schizosaccharomyces pombe)
- gi|3192027|emb|CAA19357.1| (AL023794) thymidylate kinase [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|5926720|dbj|BAA23726.2|_1:166 (AB009251) thymidine kinase [Human herpesvirus 3] (Human herpesvirus 3)
- gi|6015696|emb|CAB57523.1|_3:184 (Y18930) thymidylate kinase [Sulfolobus solfataricus] (Sulfolobus solfataricus)
- gi|8134528|sp|Q9YA48|KTHY_AERPE_1:197 PROBABLE THYMIDYLATE KINASE (DTMP KINASE) (Aeropyrum pernix)
- gi|7434643|pir||E72514 hypothetical protein APE2090 - Aeropyrum pernix (strain K1) (Aeropyrum pernix)
- gi|5105789|dbj|BAA81101.1| (AP000063) 208aa long hypothetical protein [Aeropyrum pernix] (Aeropyrum pernix)
- gi|7483979|pir||C69413_38:238 thymidylate kinase homolog - Archaeoglobus fulgidus (Archaeoglobus fulgidus)
- gi|2649268|gb|AAB89936.1| (AE001013) thymidylate kinase, putative [Archaeoglobus fulgidus] (Archaeoglobus fulgidus)
- gi|1730073|sp|P44719|KTHY_HAEIN_1:203 THYMIDYLATE KINASE (DTMP KINASE) (Haemophilus influenzae)
- gi|1573430|gb|AAC22114.1| (U32728) thymidylate kinase [Haemophilus influenzae Rd] (Haemophilus influenzae Rd)
- gi|547813|sp|P36590|KTHY_SCHPO_7:201 THYMIDYLATE KINASE (DTMP KINASE) (Schizosaccharomyces pombe)
- gi|478751|pir||S28955 dTMP kinase (EC 2.7.4.9) - fission yeast (Schizosaccharomyces pombe) (Schizosaccharomyces pombe)
- gi|4974|emb|CAA46698.1| (X65868) thymidylate kinase [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|7446649|pir||H75067_2:174 hypothetical protein PAB1012 - Pyrococcus abyssi (strain Orsay) (Pyrococcus abyssi)
- gi|5458950|emb|CAB50437.1| (AJ248287) hypothetical protein [Pyrococcus abyssi] (Pyrococcus abyssi)
- gi|6016458|sp|O30175|KTHY_ARCFU_1:189 PROBABLE THYMIDYLATE KINASE (DTMP KINASE) (Archaeoglobus fulgidus)
- gi|7434641|pir||E69257 thymidylate kinase (tmk) homolog - Archaeoglobus fulgidus (Archaeoglobus fulgidus)
- gi|2650584|gb|AAB91163.1| (AE001102) thymidylate kinase (tmk) [Archaeoglobus fulgidus] (Archaeoglobus fulgidus)
- gi|7481957|pir||S77770_2:149 probable ATP-binding pyrimidine kinase - Mycoplasma capricolum (Mycoplasma capricolum)
- gi|530420|emb|CAA83737.1| (Z33066) ATP-bind. pyrimidine kinases [Mycoplasma capricolum] (Mycoplasma capricolum)
- gi|7518683|pir||F71164_2:176 hypothetical protein PH0515 - Pyrococcus horikoshii (Pyrococcus horikoshii)
- gi|3256920|dbj|BAA29603.1| (AP000002) 195aa long hypothetical protein [Pyrococcus horikoshii] (Pyrococcus horikoshii)
- gi|7519788|pir||T12903_1:138 hypothetical protein yorR - Bacillus subtilis phage SPBc2 (Bacillus subtilis phage SPBc2)
- gi|2634421|emb|CAB13920.1| (Z99114) yorR [Bacillus subtilis] (Bacillus subtilis)
- gi|3025617|gb|AAC13112.1| (AF020713) unknown [Bacteriophage SPBc2] (Bacteriophage SPBc2)
- gi|7449772|pir||D70470_1:190 conserved hypothetical protein aq_1985 - Aquifex aeolicus (Aquifex aeolicus)
- gi|2984232|gb|AAC07761.1| (AE000766) hypothetical protein [Aquifex aeolicus] (Aquifex aeolicus)
- gi|7463781|pir||H70198_65:234 thymidylate kinase (tmk) homolog - Lyme disease spirochete (Borrelia burgdorferi)
- gi|2688733|gb|AAC67140.1| (AE001178) thymidylate kinase (tmk) [Borrelia burgdorferi] (Borrelia burgdorferi)
- gi|3123135|sp|O28278|YK01_ARCFU_1:147 HYPOTHETICAL PROTEIN AF2001 (Archaeoglobus fulgidus)
- gi|7450209|pir||H69499 conserved hypothetical protein AF2001 - Archaeoglobus fulgidus (Archaeoglobus fulgidus)
- gi|2648537|gb|AAB89254.1| (AE000964) conserved hypothetical protein [Archaeoglobus fulgidus] (Archaeoglobus fulgidus)
- gi|7939517|dbj|BAA95720.1|_14:191 (AB024028) uridine kinase-like protein [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|7450211|pir||H75093_1:152 thymidylate kinase related PAB0757 - Pyrococcus abyssi (strain Orsay) (Pyrococcus abyssi)
- gi|5458565|emb|CAB50053.1| (AJ248286) THYMIDYLATE KINASE related (EC 2.7.4.9) [Pyrococcus abyssi] (Pyrococcus abyssi)

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   1 MAEAASCARKGTKYAEGTQPFTVLIEGNIGSGKTT....YLNHFEKY.....KNDICLLTEPVEK
   2 ---AASCARKGTKYAEGTQPFTVLIEGNIGSGKTT....YLNHFEKY.....KNDICLLTEPVEK
   3 LRNCFVDAPHARAMHDGGGPRRLCIEGNIAVGKST....FVKLLMKT.....HPEWQVATEPIAE
   4 ---AFCQRPSSDKEQEKEKKSVICVEGNIAGGKTT....CLEFFSNA.....-TDVEVLTEPVSK
   5 -------AWPPDKEQEKEKKSVICVEGNIASGKTT....CLEFFSNA.....-TDVEVLTEPVSK
   6 --SPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKST....FVKLLTKT.....YPEWHVATEPVAT
   7 -RNALVDAPHARAMHDGGGPRRLCIEGNIAVGKST....FVKLLMKT.....HPEWQVATEPIAA
   8 ------------KEQEKEKKSVICVEGNIAGGKTT....CLEFFSNA.....-TDVEVLTEPVSK
   9 --SPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKST....FVKLLTKT.....YPEWHVATEPVAT
  10 --SPLEGVSSSRGLHAGCGPRRLSIEGNIAVGKST....FVKLLTKT.....YPEWHVATEPVAT
  11 --------------HDGGGPRRLCIEGNIAVGKST....FVKLLMKT.....HPEWQVATEPIAA
  12 --PRRAWPPDKDRENDKEKKAVVCIEGNIASGKTT....CLEFFSNT.....-TDVEVLMEPVLK
  13 -TPPKRSCPSFSASSEGTRIKKISIEGNIAAGKST....FVNILKQL.....CEDWEVVPEPVAR
  14 -TPPKRFCPSPSTSSEGTRIKKISIEGNIAAGKST....FVNILKQA.....SEDWEVVPEPVAR
  15 -TPPKRFCSSPSTSSEGTRIKKISIEGNIAAGKST....FVNILKQV.....CEDWEVVPEPVAR
  16 PVTVPVHLMQPHPMTEYRNAFLIYLEGVMGVGKTT....LLNSMTGMvp...QENVLSCPEPMKF
  17 PVTVPVHLMQPHPMTEYRNAFLIYLEGVMGVGKTT....LLNSMTGMvp...QENVLSCPEPMKF
  18 LVHVPVHVLYPPLHQEPIPAFFIFLEGSIGVGKTT....LLKSMRGIlp...GKNVLTFHEPMAF
  19 -----SNLLKFENCSLLETHKKISIEGNISAGKST....LINILSD-.....-NGYNVVQEPLEQ
  20 LVHVPVHLLYPPMHQELVPAFFIFLEGSIGVGKTT....LLKSMNGIlg...GKNVLAFHEPIAY
  21 LVHVPVHLLYPPKHQDPVPAFFIFLEGSIGVGKTT....LLKSMNGIlg...GKNVLAFHEPIAY
  22 -MRVPIVTHLTNHVPVIKPACSLFLEGAPGVGKTT....MLNHLKAVf....GDLTIVVPEPMRY
  23 --------MSTDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGEPLSY
  24 --------MSTDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGEPLSY
  25 --------MSTDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGEPLSY
  26 --------MSTDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGEPLSY
  27 ---------STDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGEPLSY
  28 --------MSTDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGEPLSY
  29 -KPAPAHLLYPRPPTGYTDAYFIFFEGVMGVGKTT....LLKTLARNd....MNNVIIFEEAMNY
  30 -YSYMSKMSTDFPAGPTRCATVLYFDGGIAVGKTT....ALEAAAEF.....LHNILVISEPIPY
  31 -YSYMSKMSTDFPAGPTRCATVLYFDGGIAVGKTT....ALEAAAEF.....LHNILVISEPIPY
  32 --------MSTDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGEPLSY
  33 --------MSTDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGGPLSY
  34 PRDVFNTFLGSGTCPSFKNAFFLYLEGSMGVGKTT....LIRHMREIn....GDNVISFVEPMFY
  35 -------------EHHIPKNSIITVAGTVGVGKST....LTKTLAKR.....-LGFKTSLEEVDH
  36 CQPGFTPIFQDLGEPHYVKACTVFFEGCMAAGKTT....LLNFARQTls...DDEALTIPEPMRF
  37 CQPGFTPIFQDLGEPHYVKACTVFFEGCMAAGKTT....LLNFARQTls...DDEALTIPEPMRF
  38 -LMVPVHLIRTPVTVDYRNVYLLYLEGVMGVGKST....LVNAVCGIlp...QERVTSFPEPMVY
  39 -MRVPIVTHLTNHVPVIKPACSLFLEGAPGVGKTT....MLNHLKAVf....GDLTIVVPEPMRY
  40 -MRVPIVTHLTNHVPVIKPACSLFLEGAPGVGKTT....MLNHLKAVf....GDLTIVVPEPMRY
  41 --------------------KKLSIEGNISSGKTD....VLNILRNI.....-NNVVSFHDVEDR
  42 --------------------LVIVIEGLIGVGKTT....LGNILSKE.....-LEVPFYSELNND
  43 ---------GPTPARFLPEGLVFCVEGNIGCGKST....LVKALMERva...GSGVNVVEEPVDQ
  44 ---------------------YVAVSGNIGSGKST....LTRMLAER.....-YGLRPVYEPYAE
  45 -------------------MTVIVLSGPIGAGKSS....LTSLLAEH.....-LGTQAFYEGVDN
  46 -FNYIDGLKDDTRSHFHQNSKLIVVEGNIGSGKTT....LAKQLADQ.....-LGFVHFPEFRMD
  47 --PLAYILGEKATKKMTEKSKLITVDGNICSGKSK....LAKEIAEK.....-LGLKHFPEAGIH
  48 ----------HGTCRDPVCITRVYLEGAFGIGKTT....TALAFVNGsr...VNPVFFIGEPMMY
  49 --------------------MLIVLAGTIGAGKSS....LAAALGEH.....-LGTDVFYEAVDN
  50 -------------------MTIICIDGIIGAGKST....VTHRLKK-.....-NLYKCYEEPIDK
  51 ------------SKRLTERSRVITVDGNICTGKGK....LAKEIAEK.....-LGFKHFPEAGIH
  52 -------------------MTVIVLSGPIGAGKSS....LTGILSKY.....-LGTNPFYESVDD
  53 --------------------PFIAIEGPIGAGKTT....LATMLSQK.....-FGFPMINEIVED
  54 --------------------MYVVVEGPIGVGKTS....LAQRLAQR.....-SGAELNLEVVEE
  55 --------------------MIISVDGLMGSGKTT....LLDRLEKR.....--GFKVFREPVGE
  56 -------------------ANCIVIGGMIALGKTT....IANTLANH.....IQAAKVVCELETN
  57 ----------------IMAALFIVLEGIDGSGKTTqgdlLLAHFQRQ.....GLAAVLSPEPTNG
  58 --------------------NAVVVGGMIAFGKTT....IAESLAKH.....LKGSKVIYELEEQ
  59 ------------------AALFIVLEGIDGSGKTTqgdlLLAHFQRQ.....GLAAVLSPEPTNG
  60 ---------------------SIAIGGMIAFGKST....LAQALHEK.....YQPSNVVYEMVEG
  61 -------------------VLRIYLDGPHGIGKTT....LGSELTKVlah..RADVVFVPEPMAY
  62 --------------------LRVYVDGPHGLGKTT....AASRLASE.....RGDAIYLPEPMSY
  63 YVGIAVRKMPNKSAEENMKGKFIVIEGLEGAGKSSahqsVVRVLHELg....IQDVVFTREPGGT
  64 -------------------GRLIVIEGLDRSGKST....QCQLLVDKli6heKAELFKFPDRTTA
  65 --------MSTDKTDVKMGVLRIYLDGAYGIGKTTaaeeFLHHFAIT.....PNRILLIGEPLSY
  66 --------------------KLIAIEGIDGSGKTT....LANLLKEHleskmKLNVIVTREPFSE
  67 -------------------MRIVALEGIDGSGVSThsrlLHARLAGA.....GVKSCLWKEPTEG
  68 -AGQPERFNFNRNTILLDGMRFIVIDGMDGAGKDT....HAEFVRRRyae..RGSVIVRTHPSDS
  69 -----------------MKGKFIVIEGLEGAGKSSahqsVVRVLHELg....IQDVVFTREPGGT
  70 -------------------GRLIVIEGLDRSGKST....QCQLLVDKl....ILNMKRLKLFKFP
  71 ----------------GMEKMIVGIAGKIAAGKTT....VAKFLEEF.....GFCRISCSEPLFD
  72 --------------------MLIAVEGIDGAGKTTiaayIAELLKEK.....GYKVKVLKEPGDS
  73 -----------------------------------....--------.....-------------
  74 ----------------GVEKTIVGIAGKIAAGKTT....VAKFLEEL.....GFCRISCSEPLLD
  75 -------------------MTLIILEGPDCCFKST....VAAKLSKE.....-------------
  76 -------------------MKRIGLTGNIGCGKST....VAQMFREL.....-GAYVLDADKLIH
  77 -----------------------CIEGIDGSGKTS....ITNKLKALcnd..ESRYYFTKEPSSG
  78 --------------------MLIALTGTPGTGKSS....VAERLRER.....GYKVATVVELAEK
  79 ----ISDYVSPSAPAPLKQPFVIGVAGGTASGKTT....VCNMIMSQ.....LHDQRVVLVNQDS
  80 --------------------MLIAITGTPGVGKTT....IAKLLAEK.....-LGYEY-------


        60                70                    80         90          
        |                 |                     |          |          
   1 WRNV.....NGVNLLEL...MY.....K...DPK...K.WAMPFQSYVTLTML.QSHTAPT....
   2 WRNV.....NGVNLLEL...MY.....K...DPK...K.WAMPFQSYVTLTML.QSHTAPT....
   3 WQNIq12skRLGNLLEM...MY.....Q...EPA...R.WSYTFQTLSFMSRL.KVQLEPIpg7q
   4 WRNV.....RGHNPLGL...MY.....H...DAS...R.WGLTLQTYVQLTML.DRHTRPQ....
   5 WRNV.....RGHNPLGL...MY.....H...DAS...R.WGLTLQTYVQLTML.DRHTRPQ....
   6 WQNIq12aqSLGNLLDM...MY.....R...EPA...R.WSYTFQTFSFLSRL.KVQLEPFpe7q
   7 WQNIq12skRLGNLLEM...MY.....Q...EPA...R.WSYTFQTLSFMSRL.KVQLEPIpg7q
   8 WRNV.....RGHNPLGL...MY.....H...DAS...R.WGLTLQTYVQLTML.DRHTRPQ....
   9 WQNIq12aqSLGNLLDM...MY.....R...EPA...R.WSYTFQTFSFLSRL.KVQLEPFpe7q
  10 WQNIq12aqSLGNLLDM...MY.....R...EPA...R.WSYTFQTFSFLSRL.KVQLEPFpe7q
  11 WQNIq12skRLGNLLEM...MY.....Q...EPA...R.WSYTFQTLSFMSRL.KVQLEPIpg7q
  12 WRNV.....HGHNPLSL...MY.....H...DAS...R.WGLTLQTYVQLTML.DQHTRPQ....
  13 WCNVq15qkNGGNVLQM...MY.....E...KPE...R.WSFTFQTYACLSRI.RAQLASLng7d
  14 WCNVq15qkSGGNVLQM...MY.....E...KPE...R.WSFTFQSYACLSRI.RAQLASLng7d
  15 WCNVq15qkSGGNVLQM...MY.....E...KPE...R.WSFIFQSYACLSRI.RAQLASLng7d
  16 WTCV.....YSNCLKEQrs.IV.....K...QGT...H.GKLITSARVYACQS.KFALPFRa21t
  17 WTCV.....YSNCLKEQrs.IV.....K...QGT...H.GKSITSARVYACQS.KFALPFRa21t
  18 WKNV.....F-SNSLDE...VY.....KltlPAK...V.GSMTNSSKLLACQL.KFAAPLLa18l
  19 WR--.....-GNNLLDK...LY.....K...DPS...R.WAYTFQSHAFWTRT.KTYIDALnk..
  20 WTDV.....F-SNSLEE...VY.....KltlPAK...V.GRTSNSAKLLACQL.KFASPLLa18l
  21 WTDV.....F-SNSLEE...VY.....KltlPAK...V.GRTSNSAKLLACQL.KFASPLLa18l
  22 WTHV.....Y-ENAIKA...MH.....KnvtRAR...H.GREDTSAEVLACQM.KFTTPFRv21a
  23 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  24 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  25 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  26 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  27 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  28 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  29 WKTV.....F-SDCHKL...IYdvm..K...MGK...H.GSFSVSSKLLACQM.KFLTPLKs22s
  30 WTST.....FDKNVCQQ...IY.....Dvv.KTK...E.KGKKHSKKVLQCQM.AFAQPFHa19g
  31 WTST.....FDKNVCQQ...IY.....Dvv.KTK...E.KGKKHSKKVLQCQM.AFAQPFHa19g
  32 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  33 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  34 WREV.....Y-SDCVKL...IYsac..K...PFN...L.GKMSTSKKVLSAQM.KFMTPMKc21t
  35 ----.....--NPYLEK...FY.....H...DFE...R.WSFHLQIYFLAERF.KEQKTIFe...
  36 WTEV.....Y-TNVLSQ...IV.....KinkECK...P.GKTSTTAELVSCQL.KFATPLKt21g
  37 WTEV.....Y-TNVLSQ...IV.....KinkECK...P.GKTSTTAELVSCQL.KFATPLKt21g
  38 WTRA.....FTDCYKEI...SHlm...K...SGK...A.GDPLTSAKIYSCQN.KFSLPFRt21g
  39 WTHV.....Y-ENAIKA...MH.....KnvtRAR...H.GREDTSAEVLACQM.KFTTPFRv21a
  40 WTHV.....Y-ENAIKA...MH.....KnvtRAR...H.GREDTSAEVLACQM.KFTTPFRv21a
  41 YTPI.....E-KELIRK...FH.....E...NPS...R.WSYALQTHYCMKRV.RMHLECFv...
  42 FT--.....--LAVLDK...FY.....K...DKS...R.WAFPVQINFLNERF.KLIKGVF....
  43 WVNH.....NGKNYLEL...SY.....T...DPT...G.YAVPFQNLVFDSYV.NVQ---R....
  44 ----.....--NPYLED...FY.....H...DMR...Q.YSFHSQVYFLSRRL.EQHLGMVt...
  45 ----.....--NPILPL...YY.....K...DMA...H.YTFLLNTYLLNHRL.AQINQAI....
  46 DILVd17arYRLPDISM...FY.....K...NPS...GeLSAAMQDRIFNCRF.DQYLNALahil
  47 YVDSt12qfSGNCSLEK...FY.....D...DPKsndG.NSYRLQAWLYASRL.LQYADALehll
  48 WRNM.....AGDDAING...IYg13sdN...DAQ...R.LTAYFQGLFCSPHS.MLHARILh15f
  49 ----.....--NPVLDF...YY.....Q...DPK...K.YAFLLQIYFLNKRF.KSIKEAY....
  50 WT--.....----LLPN...LY.....N...DMK...K.YATPFQFQVLFSQY.DQYLSFKd...
  51 YPDSt12dyNGNCSLEK...FY.....D...DPRsndG.NSYRLQSWLYSSRL.LQYSDALehll
  52 ----.....--NPVLPL...FY.....E...NPK...K.YAFLLQVYFLNTRF.RSIKSAL....
  53 ----.....--NPYLDK...FY.....D...NIK...E.WSFQLEMFFLCHRY.KQLEDTSdhfl
  54 ----.....--NPFLAK...FY.....E...QPQ...A.YAFQVQAFFLLSRF.KQLSQLWqpgl
  55 WK--.....----FLNK...FY.....K...NPK...K.YALALQLEILVSFT.KYT---F....
  56 DQLV.....--ELLLAK...MY.....Ers.DEL...L.YSPLFQLYFTLNRFgKYQNNCN....
  57 PVGR.....LIRQALQGdlfTY.....N...DAR...Q.FEAQMGYLFAADRH.YHLYHPGdg8l
  58 DQLA.....--DLLLAK...MY.....Ern.DEL...L.YAPLFQLYFTLNRFnKYRKECN....
  59 PVGR.....LIRQALQGdlfTY.....N...DAR...Q.FEAQMGYLFAADRH.YHLYHPGdg8l
  60 DKLM.....--DLLLAK...MY.....Ere.NNV...L.FGSLFQLYFVLNRF.ANYKNNCn...
  61 WRAV.....GGVDTIAS...VYet6rcD...NKE...I.SSEEASLIMANTQV.LMNMPYMv22p
  62 WSGA.....GEDDLVAR...VYta6rmD...RGE...I.DAREAAGVVLGAQL.TMSTPYVa21t
  63 PL--.....--AEKLRH...LI.....KhetEEP...V.TDKAELLMLYAARI.QLVENVIkpal
  64 IGKK.....IDDYLKES...VQ.....L...NDQ...V.IHLLFSANRWETIQ.YIYEQIN....
  65 WRNL.....AGEDAICG...IYg13spE...DAQ...R.LTAHFQSLFCSPHA.IMHAKISa16k
  66 ----.....----DIIK...LI.....E...KIG...W.NDPILLVLLFAADR.EIHVNWLskik
  67 PV--.....--GRLIRG...FL.....R...STE...G.VDSDLMALLFAADR.LWGLR--....
  68 LFGR.....V---AKAS...LL.....R...RGK...F.FHLMAAIFYFFDVI.YSLLR--....
  69 PL--.....--AEKLRH...LI.....KhetEEP...V.TDKAELLMLYAARI.QLVENVIkpal
  70 DRTT.....AIGKKIDD...YLt....E...SVQ...L.NDQVIHLLFSANRW.EPSIYYRanq.
  71 ILTG.....N-------...--.....-...---...-.----TQGYSWVPEV.EFKGEPT....
  72 KFGKki9rlSPEEELEL...FL.....K...DRE...I.D----------ARE.NILPALQ....
  73 ----.....--------...--.....-...---...-.-----QIYMLTARS.KQLKQAK....
  74 ILTG.....N-------...--.....-...---...-.----VSEYSWVPEV.NFKGEPT....
  75 ----.....-------L...KY.....P...IIK...G.SSFELAKSGNEKLF.EHFNKLA....
  76 SFYR.....KGHPVYEE...VVk27deE...KLR...K.LEEITHRALYKEIE.KITKNLS....
  77 II--.....--GEMIRK...QL.....M...NFEnp.L.EESTFAYLYAADRH.DHLYKKGgi8n
  78 ----.....--------...--.....-...---...-.--------------.-------....
  79 FYHS.....LTKEKLNK...VH.....Ey..NFD...H.PDAFNTEVLLSCME.KLRSGQPvnip
  80 ----.....--VNLRDF...AL.....E...KGC...G.REVDGEVEVEIDEL.AYFVEKEl...


        100       110       120       130       140            150     
         |         |         |         |         |              |     
   1 .NKKLKIMERSIFSARYCFVENMRRNGSLEQGMYNTLEEWYKFIEESI.....HVQADLIIYLRT
   2 .NKKLKIMERSIFSARYCFVENMRRNGSLEQGMYNTLEEWYKFIEESI.....HVQADLIIYLRT
   3 aEKSVRVFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLQEFan...RLLLHGFIYLQA
   4 .VSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNM.....DVSVDLIVYLRT
   5 .VSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNM.....DVSVDLIVYLRT
   6 aRKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFas...RITLHGFIYLQA
   7 aEKSVRVFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLQEFan...RLLLHGFIYLQA
   8 .VSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNM.....DVSVDLIVYLRT
   9 aRKPVQIFERSVYSDRYIFAKNLFENDSLSDIEWHIYQDWHSFLLWEFas...RITLHGFIYLQA
  10 aRKPVQIFERSVYSDRYIFAKNLFENDSLSDIEWHIYQDWHSFLLWEFas...RITLHGFIYLQA
  11 aEKSVRVFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLQEFan...RLLLHGFIYLQA
  12 .MSPVRLMERSIYSARYIFVENLYRSGKMPEVDYAILSEWFDWIVRNI.....DVSVDLIVYLRT
  13 aEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFgq...SLELDGIIYLQA
  14 aEKPVLFFERSVYSDRYIFASNLYESDCMNETEWTIYQDWHDWMNSQFgq...SLELDGIIYLRA
  15 aEKPVLFFERSVYSDRYIFASNLYESDCMNETEWTIYQDWHDWMNSQFgq...SLELDGIIYLRA
  16 kPANWIVFDRHLLSATVVFPLVHVKYNRLTPDHLFQILSLFSA-----.....-HDGDVVVLLTL
  17 kPANWIVFDRHLLSATVVFPLVHVKYNRLTPDHLFQILSLFSA-----.....-HDGDVVVLLTL
  18 sSNMWVMFDRHPLSATVVFPYMHYQNGFLSFSHLVHLWGSFRA-----.....-SHGDNIILLNL
  19 .NKGNIILERSVFSDKYIFATALHDIGYIDDTEWNIYNEYSKWMTEFM.....DIKIDGIIYLKT
  20 sSDMWVMFDRHPLSATVVFPYMHFQNGFLSFSHLIQLWSSFKA-----.....-SQGDNIILLNL
  21 sSDMWVMFDRHPLSATVVFPYMHFQNGFLSFSHLIQLWSSFKA-----.....-SRGDNIILLNL
  22 pLDCWILHDRHLLSASVVFPLMLLRSQLLSYSDFIQVLATFTA-----.....-DPGDTIVWMKL
  23 ePYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPA-----.....EPPGTNLVVCTV
  24 ePYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPA-----.....EPPGTNLVVCTV
  25 ePYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPA-----.....EPPGTNLVVCTV
  26 ePYKIMLSDRHPIASTICFPLSRYLVGDMSPAAPPGLLFTLPA-----.....EPPGTNLVVCTV
  27 ePYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPA-----.....EPPGTNLVVCTV
  28 ePYKIMLSDRHPIASTICFPLSGYLVGDMSPAALPGLLFTLPA-----.....EPPGTNLVVCTV
  29 dVSHWVMFDRHALSACLVFPLVMLKSGMLSFEHFISLVSTFRA-----.....-NEGDIIVLIAL
  30 tCNNYVLIDRHMVSPTVIFPCLFFRLGVLRFCDLLSLLSVFSA-----.....-QKFDNVVLFKL
  31 tCNNYVLIDRHMVSPTVIFPCLFFRLGVLRFCDLLSLLSVFSA-----.....-QKFDNVVLFKL
  32 ePYKIMLSDQHPIASTICFPLSRYLVGDMSPAALPGLLFTLPA-----.....EPPGTNLVVCTV
  33 ePYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPA-----.....EPPGTNLVVCTV
  34 aMDNWLLFDRHPLSATLVFPYLSLKNGYLAFEHFLALAANFTA-----.....-HEGDIIALLCM
  35 .AGGGFVQDRSIYEDTGIFAKMHADKGTMSKVDYKTYTSLFEAMVMTPy....FPHPDVLIYLEG
  36 pLDKWVIVDRHQLSALVVFPLVLMRRGMLSFSDFFNLLGMFEA-----.....-HPGEVIALMSV
  37 pLDKWVIVDRHQLSALVVFPLVLMRRGMLSFSDFFNLLGMFEA-----.....-HPGEVIALMSV
  38 rGTHWCVFDRHLLSPAVVFPLMHLKHGRLSFDHFFQLLSIFRA-----.....-TEGDVVAILTL
  39 pLDCWILHDRHLLSASVVFPLMLLRSQLLSYSDFIQVLATFTA-----.....-DPGDTIVWMKL
  40 pLDCWILHDRHLLSASVVFPLMLLRSQLLSYSDFIQVLATFTA-----.....-DPGDTIVWMKL
  41 .PSRVNILERSIFSDRYVFAEAATALGYMDDPEWALYCKQHDWYTDKL.....EIQFDGIIYLRT
  42 .RTKGGILDRSIYGD-CVFASLLNCDGHISDEEYKIYIDLLDNMLEHS.....-QRPSLLVYLDC
  43 .LQNPDIMERSPMSATRVFCAVNGSRGVIPATALPGMAARGEAVMRTI.....-ATRPVFVYLEL
  44 .GARYVIQDRTVFEDANIFARNLYESGQMGERDWQTYRGLYEGVLPAL.....-RVPDLLIHIDA
  45 .RDHNSVSDRSIYED-ALFFKMNVDSGIADPTEFKIYDSLLENMMEQApgnp.SKKPDLLIYIHV
  46 nTGQGVVLERTPHSD-FVFANAMRDKNYIGHEYFKHYYFVRKNALPQL.....HFWPHLVVYLNT
  47 sTGQGVVLERSIYSD-FVFLEAMYRQGFIRKQCVDHYNQVKKVTICEY.....-LPPHVVVYVDV
  48 fNNPVAIFDRHPVASNVCFPISRYVVGDMTPATLPGFLFAVSE-----.....EPEGTNLIVCTV
  49 .QADNNILDRSIFED-ELFLKLNYKNGNVTKTELDIYQELLANMLEELegmp.KKRPDLLIYIDV
  50 .CKETVVVERCPWTSKNIFTSLMIENNLFDLSAIDTYNNLYER----L.....SYQVDHFIYIKV
  51 tTGQGVVLERSIFSD-FVFLEAMYNQGFIRKQCVDHYNEVKSVTICDY.....-LPPHLVIYIDV
  52 .TDDNNVLDRSIYED-ALFFQMNADIGRATPEEVDTYYELLHNMMSELdrmp.KKNPDLLVHIDV
  53 kKGQPVIADYHIYKN-VIFAE-----RTLSPHQLEKYKKIYHLLTDDL.....-PKPNFIIYIKA
  54 .YRPEVVSDYLFDKD-FIFAAMN-----LRDAEFDLYQDLYGHLSPRL.....-PTPDLVVYLRA
  55 .TEDIVFTERCPQVSHYVFAKMLSAKGTLTDEEMATYKNFYDKMN---.....LWKPDVHIFLKC
  56 .TINPTIFDRSIFED-WLFA----KHNIIRPAVFSYYNQLWNRLAKELvnk..HGVPNLYVILDG
  57 aQQCHVITTRYYFSS------------LAYNCHTEADWEFVQRLNQSF.....-PQPDWVIYLDL
  58 .NKTPTIFDRSIFED-WLFA----KQNIHRPSIFTYYNHLWNGIVKELifk..HGIPALYVILEG
  59 aQQCHVITTRYYFSS------------LAYNCHTEADWEFVQRLNQSF.....-PQPDWVIYLDL
  60 .RKSLTIFDRSIFED-WLFAHANIDK----PSVFSYYDGLWQGVCKELiye..HGVPKLYVILDG
  61 lPGQTIIVDRHPIASLLCYPLARYLRGSFTLQTAMSLLAFIPK-----.....IPHGTNLVLGKL
  62 pPDLILIFDRHPTASLLCYPLARYLTRCLPIESVLSLIALIPP-----.....TPPGTNLILGTA
  63 mQGKWVVGDRHDMSS----QAYQGGGRQLDPHFMLTLKETVLG-----.....NFEPDLTIYLDI
  64 .KGVTCILDRYAFSG------------IAFSAAKGLDWEWCKSPDRGL.....-PRPDLVIFLNV
  65 ePYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPA-----.....DPP---------
  66 .DADLIILDRYYFSS------------IAYQGALGVDEQWIKMVNSYF.....-PKPDMVILLDL
  67 .---LGVVERCGGSP-EVLVVDRYKYSSLAYQGVGSGLEWVDAVNRKA.....-PEAEILVYIDV
  68 .--------YYGRAETVIFVRYLGGVLYLPERYARVLYRFFRSVL---.....-PTSPYMFYLEA
  69 mQGKWVVGDRHDMSS----QAYQGGGRQLDPHFMLTLKETVLG-----.....NFEPDLTIYLDI
  70 .QRCNCILDRYAFSG------------IAFSAAKGLDWEWCKSPDRGL.....-TRPDLVIFLNV
  71 .RENLIELGRILKEKYGEDILIRLAVDKLRNCENIAIDGVRSMGEVDAi....KRMGGIVVYIEA
  72 .SGYAVVMDRYYFSN------------IAYQSARGIDARLIREMNEKI.....APKPDLTILLDV
  73 .NLENIIFDRTLLED-PIFMKVNYDLNNVDQIDYNTYIEFYNNVVLENlk6enKLSFDIVIYLRV
  74 .RENLIELGRLLKEKYGEDILIRLAIDKLRRCKNIAIDGVRSLGEVEAi....KRMGGIIIYIEA
  75 .DEDNVIIDRFVYSN-LVYAKKFKDYSILTERQLRFIEDKIKA-----.....---KAKVVYLHA
  76 .EDTLFILEASLLVE----------------------KGTYKN-----.....---YDKLIVVYA
  77 tKSRKIITDRYLFSS-------------------IAYQGKLGYELNKN.....FPLPEKVFFIET
  78 .--HGCIIDEEDGEI-VIDVESLAAR--------IDFEGIVEGHLSHL.....-LKPDVAIVLRC
  79 .SYDFKIHQSIESSS------------PVNPGDVIILEGILVLNDPRV.....RDLMNMKIFVDT
  80 .KDRNVVLDGHLSHL---------------------------------.....-MPVDLVVVLRA


        160       170                180       190            200      
         |         |                  |         |              |      
   1 SPEVAYERIRQRARSEES.....CVPL....KYLQELHELHEDWLIH.....QRRPQSC....KV
   2 SPEVAYERIRQRARSEES.....CVPL....KYLQELHELHEDWLIH.....QRRPQSC....KV
   3 SPQVCMERLYQRDREEEK.....GIEL....AYLQQLHSQHEDWFINkt6lhFEALQHV....PV
   4 NPETCYQRLKKRCREEEK.....VIPL....EYLEAIHHLHEEWLIKg....SLFPMAA....PV
   5 NPETCYQRLKKRCREEEK.....VIPL....EYLEAIHHLHEEWLIKg....SLFPMAA....PV
   6 SPQVCLKRLYQRAREEEK.....GIEL....AYLEQLHGQHEAWLIHkt6lhFEALMNI....PV
   7 SPQVCMERLYQRDREEEK.....GIEL....AYLQQLHSQHEDWFINkt6lhFEALQHV....PV
   8 NPETCYQRLKKRCREEEK.....VIPL....EYLEAIHHLHEEWLIKg....SLFPMAA....PV
   9 SPQVCLKRLYQRAREEEE.....GIEL....AYLEQLHGQHEAWLIHkt6lhFEALMNI....PV
  10 SPQVCLKRLYQRAREEEE.....GIEL....AYLEQLHGQHEAWLIHkt6lhFEALMNI....PV
  11 SPQVCMERLYQRDREEEK.....GIEL....AYLQQLHSQHEDWFINkt6lhFEALQHV....PV
  12 TPEICYQRLKMRCREEEK.....VIPM....EYLHAIHRLYEEWLVNg....SLFPAAA....PV
  13 TPETCLHRIYLRGRNEEQ.....GIPL....EYLEKLHYKHESWLLHrt6tnFDYLQEV....PI
  14 TPEKCLNRIYLRGRNEEQ.....GIPL....EYLEKLHYKHESWLLHrt6tsFDYLQEV....PV
  15 TPEKCLNRIYIRGRDEEQ.....GIPL....EYLEKLHYKHESWLLHrt6tnFEYLQEV....PI
  16 NSSEAHRRIQSRGRKEEK.....GITQ....NYLRQVAWAYHAVFCT.....WVMMQYLt...PE
  17 NSSEAHRRIQSRGRKEEK.....GITQ....NYLRQVAWAYHAVFCT.....WVMMQYLt...PE
  18 NSQENLERVKRRNRKEEK.....CVSL....EHIRMLNSCYHAVYCA.....WLLVQNFt...PE
  19 SPDICYKRMLNRARHEEN.....TVKI....DYLNLLHDKHEKWLSEn....NEHEFKV....PV
  20 NSQENLKRVRKRNRKEEK.....SVSI....EHIRLLNNCYHAVYCA.....WLLVQNFt...PE
  21 NSQENLKRVKKRNRKEEK.....SVSI....EHIRLLNNCYHAVYCA.....WLLVQNFt...PE
  22 NVEENMRRLKKRGRKHES.....GLDA....GYLKSVNDAYHAVYCA.....WLLTQYFa...PE
  23 SLPSHLSRVSKRARPGE-.....TVNL....PFVMVLRNVYIMLINT.....IIFLK--....--
  24 SLPSHLSRVSKRARPGE-.....TVNL....PFVMVLRNVYIMLINT.....IIFLK--....--
  25 SLPSHLSRVSKRARPGE-.....TVNL....PFVMVLRNVYIMLINT.....IIFLK--....--
  26 SLPSHLSRVSKRARPGE-.....TVNL....PFVMVLRNVYIMLINT.....IIFLK--....--
  27 SLPSHLSRVSKRARPGE-.....TVNL....PFVMVLRNVYIMLINT.....IIFLK--....--
  28 SLPSHLSRVSKRARPGE-.....TVNL....PFVMVLRNVYIMLINT.....IIFLK--....--
  29 DHGEAIRRIKTRKRPEEE.....TISL....TYVIRLHWCFVAVYNT.....WRLLQYFt...AR
  30 HPKVAATRVKERGRNPEG.....VINH....TYLQLLNEVLDAIFCA.....WELLAIVp...PE
  31 HPKVAATRVKERGRNPEG.....VINH....TYLQLLNEVLDAIFCA.....WELLAIVp...PE
  32 SLPSHLSRVSKRARPGE-.....TVNL....PFVMVLRNVYIMLINT.....IIFLK--....--
  33 SLPSHLSRVSKRARPGE-.....TVNL....PFVMVLRNVYIMLINT.....IIFLK--....--
  34 GEEDNLKMVKLRNRKGES.....GVTS....AHLKDLGQAFHACYCT.....WLLLKYLs...PE
  35 DLENILNRIEQRGREMEL.....QTSR....SYWEEMHTRYENWISG.....F---NAC....PV
  36 NVEENFTRLKKRGRVCER.....HIDR....DYIKEIKGSFNAAYCA.....WLFLQYF....S-
  37 NVEENFTRLKKRGRVCER.....HIDR....DYIKEIKGSFNAAYCA.....WLFLQYF....S-
  38 SSAESLRRVRARGRKNDG.....TVEQ....NYIRELAWAYHAVYCS.....WIMLQYIt...VE
  39 NVEENMRRLKKRGRKHES.....GLDA....GYLKSVNDAYHAVYCA.....WLLTQYFa...PE
  40 NVEENMRRLKKRGRKHES.....GLDA....GYLKSVNDAYHAVYCA.....WLLTQYFa...PE
  41 IPESCKERINEKSITEKNyp...NISI....DYLKTLHEKHELWLTQ.....C---KKV....PV
  42 SIDEVERRIKNRNRSFEM.....NIPR....DYLEGLNRKYLKWYDE.....YNLSSKI....KF
  43 PPEECLRRMRRRDRTGEA.....GVGL....DYLRLLHERYEAWLSS.....-----AE....DV
  44 GLPTLRRRIALRGRDYEQ.....AIPD....EYLAGLNRLYAGWIAA.....F---DLC....PV
  45 SLDTMLHRIQKRGRKFEQ.....LSTDpslkDYYARLLSYYEPWY--.....-EKYNAS....PK
  46 PTNKCLENIKRRGNTDEIa....TVDE....RYLKTIEESYKDSLRE.....YR--NHS....KI
  47 PVPEVQSRIQKKGNPHEM.....KITS....AYLQDIENAYKGTFLPemsekCEVLQYS....AW
  48 SLTNHLTRITNRSRSGE-.....IIDV....QFILVLRNVYIMLINT.....IRYLQAK....SD
  49 SFDKMLERIEKRGRSFEQvd...--GNpsleQYYHQVHGEYPTWYED.....Y---KVS....PK
  50 DSEMAFERIKKRDRFAEQ.....NISF....DYLKSLENKYATSLAT.....---LSPS....TV
  51 PVPEVQRRIQKKGDPHEM.....KITS....AYLQDIENAYKKTFLPemsekCEVLQYS....AR
  52 SYDTMLKRIQKRGRNYEQls...--YDptleDYYKRLLRYYKPWYAK.....Y---DYS....PK
  53 SLPTLLHRIEKRGRPFEK.....KIET....SYLEQLISDYEVAIKQl....QEADPEL....TV
  54 DPPELLRRIARRGRPFEH.....DMKA....AYLADLTGRYDDYFRT.....Y----AH....PH
  55 PIDVCEQRLKRRSDSY--.....TIDT....EYMERLEKYYSIFN--.....-KYTNST....PI
  56 DWKLFEKRLFMRNRKVEIdnf..TKNQ....LYFQNLHRVYTGFMEA.....VCNDFGI....NY
  57 PVDLALQRLGDRQQLEDQaprecYEQR....EKLISVHRNYDRIFAH.....Y----QG....QL
  58 DWELFEQRLFQRNRKVEIdnf..AKNK....DYFKNLYKIYGEFIKN.....VCYDFGI....SH
  59 PVDLALQRLGDRQQLEDQaprecYEQR....EKLISVHRNYDRIFAH.....Y----QG....QL
  60 DWELFKERIFKRNRKVEIdnf..SINE....TYFKRLLEMYKNYMVN.....VCKDFGI....NY
  61 SGGETTQRLYERGRPGE-.....VVDW....HMIECIHNIYDRLQNT.....VTYIQQG....NN
  62 PAEDHLSRLVARGPPGE-.....LPDA....RMLRAIRYVYALLANT.....VKYLQSG....GS
  63 DPSVGLARARGRGELDRIe....QMDL....DFFHRTRARYLELVKD.....-----NP....KA
  64 DPRIAATR---GQYGEER.....YEKI....EMQEKVLKNFQRLQKE.....F-REEGL....EF
  65 ------------------.....----....----------------.....-------....--
  66 PIEVAISRIKNDKFNFEE.....KIKS....--LAKVREKYLKLA--.....----KEY....NF
  67 PTEVALRRITARERR-EV.....FETP....EFLERVKSMYEEVL--.....-RLARAR....GV
  68 EPEVCMERVARRSES-EM.....FENI....EDFRRVRERAFRILKG.....W------....--
  69 DPSVGLARARGRGELDRIe....QMDL....DFFHRTRARYLELVKD.....-----NP....KA
  70 DPRIAATR---GQYGEER.....YEKI....EMQEKVLKNLQRLQKE.....F-REEGL....EF
  71 KPEIRFERLRRRGSSKDR.....GIKS....--LEDLLK-FDEWE--.....-EKLYET....TK
  72 EPEIALERVRKRGKLSP-.....FEKL....DYLRKVRKCFLENA--.....-----DE....TT
  73 STKTAISRIKKRGRSEEP.....LIGD....EYWETLNKNYEEFYKQ.....NV--YNF....PF
  74 RAEVRFERLRKRCSEKDR.....GIKT....--LQDLLR-FDEWE--.....-ERLYST....TN
  75 DPSVIKKRLRVRGDE---.....YIEG....KDIDSILELYREVMSN.....-------....--
  76 PYEVCKERAIKRGMSEED.....FERR....------------WKKQmp...IEEKVKY....AD
  77 DPNIAYERIQKNRTQSDLfe...LEKY....KTFEQIALKYLKIFKK.....LE--KKI....NV
  78 NPAVLRERLKGRNWSEE-.....----....KLLENLEAEMLDVILV.....EALEHAS....EV
  79 DADVRLSRRIQRDTVER-.....GRN-....--IQNVLEQYTKFVKP.....-------....--
  80 HPRIIGERLRERGYSKEKig...-ENV....----------EAELVD.....AILIEAIdeheNV


             210       220       230       240       250
              |         |         |         |         |
   1 LVLDAD..LNLENIGTEYQRSESSIFDAISSNQQPSPVLVSPSKRQRVAR
   2 LVLDAD..LNLENIGTEYQRSESSIFDAISSNQQPSPVLVSPSKRQRVA-
   3 LVLDVT..EDFSENAARQEELMGQV-------------------------
   4 LVIEAD..HHMERM--------------LELFEQNRDRILTPENRKH---
   5 LVIEAD..HHMERM--------------LELFEQNRDRILTPENRKH---
   6 LVLDVN..DDFSEEVTKQEDLMREV-------------------------
   7 LVLDVT..EDFSENAARQEELMGQV-------------------------
   8 LVIEAD..HHMERM--------------LELFEQNRDRILTPENRKH---
   9 LVLDVN..DDFSEEVTKQEDLMREV-------------------------
  10 LVLDVN..DDFSEEVTKQEDLMREV-------------------------
  11 LVLDVT..EDFSENAARQEELMGQV-------------------------
  12 LVIEAD..HNLEKM--------------LELFEQNRARILTPENWKHW--
  13 LTLDVN..EDFKDKYESLVEKVKEFL------------------------
  14 LTLDVN..EDFKDKHESLVEKVKEFL------------------------
  15 LTLDVN..LDFKDKEESLVEKVKEFL------------------------
  16 QMVQLC..VQTVSIE-----------------------------------
  17 QMVQLC..VQTVSIE-----------------------------------
  18 EIVEVC..FNTKQI-TDLRSSKPSFLEKHVSIED----------------
  19 LEINGD..GDFIDDSNRQSSILSNIYDFI---------------------
  20 EIVEVC..FNAKHI-TDLSSSKPSFLAKHVSTE-----------------
  21 EIVEVC..FNAKHI-TDLSSSKPSFLAKHVSTE-----------------
  22 DIVKVC..AGLTTIT-----------------------------------
  23 ------..------------------------------------------
  24 ------..------------------------------------------
  25 ------..------------------------------------------
  26 ------..------------------------------------------
  27 ------..------------------------------------------
  28 ------..------------------------------------------
  29 EATEVC..LDIKT-------------------------------------
  30 VIVDAM..LSQTSVKTVF--------------------------------
  31 VIVDAM..LSQTSVKTVF--------------------------------
  32 ------..------------------------------------------
  33 ------..------------------------------------------
  34 DMVSVCc.CDVTLNDICIMRSM----------------------------
  35 LKLRIEd.YDLLNDENSIENIVDQIASVIHD-------------------
  36 ------..------------------------------------------
  37 ------..------------------------------------------
  38 QMVQLC..VQTTNIP-----------------------------------
  39 DIVKVC..AGLTTIT-----------------------------------
  40 DIVKVC..AGLTTIT-----------------------------------
  41 LIIDGE..EDFIFDPCAKKKLINEVTEFI---------------------
  42 SYDNIN..IFSEEDRNKVISL-----------------------------
  43 ERVDAS..RSREEIVDRVIEI-----------------------------
  44 VRVDGDa.LDFVHDPQAFEWVCGR--------------------------
  45 MMIDGDk.YDFVANEDARRKVINAIDQKLIDI------------------
  46 LAYDWTkpGDTDAVVEDIERLDLDFFEWHS--------------------
  47 EAQDAE..KVVEDIE-----------------------------------
  48 WLIDW-..------------------------------------------
  49 MKIDGNs.LDFVQNPQDLATVLKMID------------------------
  50 TIIDGS..NTIEEVEFDVKTAINNF-------------------------
  51 EAQDSK..KVVEDIE-----------------------------------
  52 MTIDGDk.LDFMASEEDRQEVLNQIVAKLKEMGK----------------
  53 LTVDGDs.KDFVLNKSDFERIAAHV-------------------------
  54 LILEAGn.YDFVANEADQQAIFDQIDAA----------------------
  55 KFIDAS..KNEDEVEEDFMNQVKDF-------------------------
  56 CIIDAK..LPIVTIIKMILE------------------------------
  57 CRLDAS..LPVEQLHQAIITKVEE--------------------------
  58 CIVNAN..QSVESITKQVLEVL----------------------------
  59 CRLDAS..LPVEQLHQAIITKVEE--------------------------
  60 VVLDAN..NSVEQNVDEVTKILQK--------------------------
  61 WRDDW-..------------------------------------------
  62 WRADL-..------------------------------------------
  63 VVINAE..QSIELVQADIESAVKN--------------------------
  64 ITLDAS..SSLEDVHSQIVDLVSNV-------------------------
  65 ------..------------------------------------------
  66 YVVDAS..KDKNEVLEQAIKII----------------------------
  67 KVIRVE..GVRGGVERGIEDVQGEIAE-----------------------
  68 KFINTN..RPIEETRREIERILSEL-------------------------
  69 VVINAE..QSIELVQADIESAVKN--------------------------
  70 ITLDASs.YALEDVDSQIVDLVSNV-------------------------
  71 IKEKAD..IVIV--------------------------------------
  72 VVVDAS..KPLEEVKEEVRKVIESFL------------------------
  73 FVVDAE..LDVKAQIELIMNKLNSI-------------------------
  74 IKEKAD..FVILNE------------------------------------
  75 ------..------------------------------------------
  76 YVIDNS..GSIEETYKQVKKVYE---------------------------
  77 I-----..------------------------------------------
  78 YEIDTTe.MSLEEVIEAVEAIIR---------------------------
  79 ------..------------------------------------------
  80 IEVDTTn.KTPEEIVEEIIGLIK---------------------------