a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1999.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0116-1-500 MutS, Thermus Aquaticus
- gi|2497995|sp|Q56215|MUTS_THEAQ_3:500 DNA MISMATCH REPAIR PROTEIN MUTS (Thermus aquaticus)
- gi|1203807|gb|AAC43637.1| (U33117) MutS [Thermus aquaticus] (Thermus aquaticus)
- gi|1588400|prf||2208391A MutS-like protein [Thermus aquaticus] (Thermus aquaticus)
- gi|4887554|emb|CAB43497.1|_6:524 (AJ006210) mismatch repair protein [Escherichia coli] (Escherichia coli)
- gi|127556|sp|P23909|MUTS_ECOLI_6:524 DNA MISMATCH REPAIR PROTEIN MUTS (Escherichia coli)
- gi|2121105|pir||I54964 DNA mismatch repair protein - Escherichia coli (Escherichia coli)
- gi|146906|gb|AAA24188.1| (M64730) DNA mismatch repair protein [Escherichia coli] (Escherichia coli)
- gi|882626|gb|AAA69243.1| (U29579) DNA mismatch repair protein [Escherichia coli] (Escherichia coli)
- gi|1789089|gb|AAC75775.1| (AE000357) methyl-directed mismatch repair [Escherichia coli] (Escherichia coli)
- gi|1592569|gb|AAB97931.1|_6:524 (U69873) DNA mismatch repair protein [Escherichia coli] (Escherichia coli)
- gi|2497996|sp|Q56239|MUTS_THETH_10:508 DNA MISMATCH REPAIR PROTEIN MUTS (Thermus thermophilus)
- gi|1871501|dbj|BAA09880.1|_10:508 (D63810) MutS [Thermus thermophilus] (Thermus thermophilus)
- gi|1171081|sp|P44834|MUTS_HAEIN_3:526 DNA MISMATCH REPAIR PROTEIN MUTS (Haemophilus influenzae)
- gi|1074024|pir||G64087 DNA mismatch repair protein mutS - Haemophilus influenzae (strain Rd KW20) (Haemophilus influenzae)
- gi|1573708|gb|AAC22364.1| (U32753) DNA mismatch repair protein (mutS) [Haemophilus influenzae Rd] (Haemophilus influenzae Rd)
- gi|127555|sp|P27345|MUTS_AZOVI_3:523 DNA MISMATCH REPAIR PROTEIN MUTS (Azotobacter vinelandii)
- gi|1073104|pir||A53296 DNA mismatch repair protein MutS - Azotobacter vinelandii (Azotobacter vinelandii)
- gi|142306|gb|AAA16868.1| (M63007) mutS [Azotobacter vinelandii] (Azotobacter vinelandii)
- gi|7229490|gb|AAF42850.1|_4:523 (AF220055) mismatch repair protein MutS [Pseudomonas aeruginosa] (Pseudomonas aeruginosa)
- gi|7108493|gb|AAF36440.1|AF126491_1_4:523 (AF126491) mismatch repair system component MutS [Pseudomonas aeruginosa] (Pseudomonas aeruginosa)
- gi|9654962|gb|AAF93703.1|_7:531 (AE004139) DNA mismatch repair protein MutS [Vibrio cholerae] (Vibrio cholerae)
- gi|2145507|pir||S62790_18:507 mismatch DNA recognition protein mutS - Thermus aquaticus (fragment) (Thermus aquaticus)
- gi|417330|sp|P10339|MUTS_SALTY_7:525 DNA MISMATCH REPAIR PROTEIN MUTS (Salmonella typhimurium)
- gi|7387928|sp|Q9ZIX6|MUTS_THECA_8:506 DNA MISMATCH REPAIR PROTEIN MUTS (Thermus caldophilus)
- gi|4102012|gb|AAD01407.1| (AF007553) mismatch repair protein [Thermus caldophilus] (Thermus caldophilus)
- gi|1619909|gb|AAB16999.1|_3:501 (U71155) DNA mismatch repair protein [Thermotoga maritima] (Thermotoga maritima)
- gi|7448104|pir||I64827_19:575 gene MSH2 protein - human (Homo sapiens)
- gi|1000885|gb|AAB59572.1| (L47580) The deletion results in premature stop [Homo sapiens] (Homo sapiens)
- gi|2135744|pir||I37550_19:575 mismatch repair protein MSH2 - human (Homo sapiens)
- gi|1079805|gb|AAA82080.1| (U41221) similar to S. cerevisiae Msh2p (Swiss-Prot accession number P25847) and bacterial MutS proteins (Swiss-Prot accession numbers P23909, P10339, and P27345) [Homo sapiens] (Homo sapiens)
- gi|4557761|ref|NP_000242.1|_19:575 mutS homolog 2 (Homo sapiens)
- gi|1171032|sp|P43246|MSH2_HUMAN DNA MISMATCH REPAIR PROTEIN MSH2 (Homo sapiens)
- gi|1082595|pir||A49268 mismatch recognition protein MSH2 - human (Homo sapiens)
- gi|7448106|pir||I64819 DNA mismatch repair protein - human (Homo sapiens)
- gi|432998|gb|AAA61870.1| (U04045) homolog of bacterial MutS proteins [Swiss-Prot accession numbers P23909, P10339, and P27345]; germline mutations are responsible for hereditary nonpolyposis colon cancer (HNPCC) [Homo sapiens] (Homo sapiens)
- gi|433147|gb|AAA18643.1| (U03911) homolog of S. cerevisiae Msh2p [Swiss-Prot accession number P25847] and bacterial MutS proteins [Swiss-Prot accession numbers P23909, P10339, and P27345] [Homo sapiens] (Homo sapiens)
- gi|1000867|gb|AAB59564.1| (L47583) DNA mismatch repair protein [Homo sapiens] (Homo sapiens)
- gi|1000869|gb|AAB59565.1| (L47582) DNA mismatch repair protein [Homo sapiens] (Homo sapiens)
- gi|1000881|gb|AAA76858.1| (L47581) DNA mismatch repair protein [Homo sapiens] (Homo sapiens)
- gi|6226653|sp|P74926|MUTS_THEMA_3:501 DNA MISMATCH REPAIR PROTEIN MUTS (Thermotoga maritima)
- gi|7448113|pir||C72219 DNA mismatch repair protein - Thermotoga maritima (strain MSB8) (Thermotoga maritima)
- gi|4982296|gb|AAD36785.1|AE001811_5 (AE001811) DNA mismatch repair protein [Thermotoga maritima] (Thermotoga maritima)
- gi|7404405|sp|P73769|MUTS_SYNY3_22:561 DNA MISMATCH REPAIR PROTEIN MUTS (Synechocystis PCC6803)
- gi|7448108|pir||S74860_56:595 DNA mismatch repair protein - Synechocystis sp. (strain PCC 6803) (Synechocystis sp.)
- gi|1652903|dbj|BAA17821.1| (D90909) DNA mismatch repair protein [Synechocystis sp.] (Synechocystis sp.)
- gi|6678938|ref|NP_032654.1|_19:575 mutS homolog 2 (E. coli) (Mus musculus)
- gi|1171033|sp|P43247|MSH2_MOUSE DNA MISMATCH REPAIR PROTEIN MSH2 (Mus musculus)
- gi|1083295|pir||S53608 DNA mismatch repair protein MSH2 - mouse (Mus musculus)
- gi|534945|emb|CAA57049.1| (X81143) MSH2 [Mus musculus] (Mus musculus)
- gi|726086|gb|AAA75027.1|_19:575 (U21011) MutS homolog 2 [Mus musculus] (Mus musculus)
- gi|7512474|pir||JC5839_394:1024 GTBP-N protein - human (Homo sapiens)
- gi|2696086|dbj|BAA23674.1| (D89645) GTBP-N [Homo sapiens] (Homo sapiens)
- gi|4504191|ref|NP_000170.1|_394:1024 mutS (E. coli) homolog 6 (Homo sapiens)
- gi|1294813|gb|AAC50461.1| (U28946) G/T mismatch binding protein [Homo sapiens] (Homo sapiens)
- gi|6063479|gb|AAB39212.2| (U54777) hMSH6 protein [Homo sapiens] (Homo sapiens)
- gi|1082386|pir||A56742_326:956 G/T-binding protein - human (Homo sapiens)
- gi|1709123|sp|P52701|MSH6_HUMAN_394:1024 DNA MISMATCH REPAIR PROTEIN MSH6 (MUTS-ALPHA 160 KDA SUBUNIT) (G/T MISMATCH BINDING PROTEIN) (GTBP) (GTMBP) (P160) (Homo sapiens)
- gi|1840467|gb|AAB47425.1| (U73737) bacterial MutS homolog [Homo sapiens] (Homo sapiens)
- gi|79102|pir||A28668_7:524 DNA mismatch repair protein mutS - Salmonella typhimurium (Salmonella typhimurium)
- gi|154188|gb|AAA27167.1| (M18965) mismatch repair protein (MutS) [Salmonella typhimurium] (Salmonella typhimurium)
- gi|565092|gb|AAA80578.1| (U16303) DNA mismatch repair protein [Salmonella typhimurium] (Salmonella typhimurium)
- gi|6754744|ref|NP_034960.1|_393:1021 mutS homolog 6 (E. coli) (Mus musculus)
- gi|2665637|gb|AAB88445.1| (AF031087) mismatch repair protein MSH6 [Mus musculus] (Mus musculus)
- gi|1709122|sp|P54275|MSH2_RAT_19:575 DNA MISMATCH REPAIR PROTEIN MSH2 (Rattus norvegicus)
- gi|7448105|pir||JC6184 mismatch repair protein homolog MSH2 - rat (Rattus norvegicus)
- gi|1103621|emb|CAA63789.1| (X93591) MSH2 protein [Rattus norvegicus] (Rattus norvegicus)
- gi|7512473|pir||JC5840_394:1024 GTBP-ALT protein - human (Homo sapiens)
- gi|2662381|dbj|BAA23675.1| (D89646) GTBP-ALT [Homo sapiens] (Homo sapiens)
- gi|2696085|dbj|BAA23673.1| (D89645) GTBP-ALT [Homo sapiens] (Homo sapiens)
- gi|2506881|sp|P54276|MSH6_MOUSE_393:1021 DNA MISMATCH REPAIR PROTEIN MSH6 (MUTS-ALPHA 160 KDA SUBUNIT) (G/T MISMATCH BINDING PROTEIN) (GTBP) (GTMBP) (P160) (Mus musculus)
- gi|1817725|gb|AAC53034.1| (U42190) G/T-mismatch binding protein [Mus musculus] (Mus musculus)
- gi|123080|sp|P10564|HEXA_STRPN_4:509 DNA MISMATCH REPAIR PROTEIN HEXA (Streptococcus pneumoniae)
- gi|80013|pir||C28667 DNA mismatch repair protein hexA - Streptococcus pneumoniae (Streptococcus pneumoniae)
- gi|153655|gb|AAA88597.1| (M18729) mismatch repair protein [Streptococcus pneumoniae] (Streptococcus pneumoniae)
- gi|7387913|sp|O84797|MUTS_CHLTR_4:526 DNA MISMATCH REPAIR PROTEIN MUTS (Chlamydia trachomatis)
- gi|7448116|pir||D71471 probable DNA mismatch repair - Chlamydia trachomatis (serotype D, strain UW3/Cx) (Chlamydia trachomatis)
- gi|3329257|gb|AAC68387.1| (AE001351) DNA Mismatch Repair [Chlamydia trachomatis] (Chlamydia trachomatis)
- gi|7227419|gb|AAF42468.1|_4:518 (AE002564) DNA mismatch repair protein MutS [Neisseria meningitidis MC58] (Neisseria meningitidis MC58)
- gi|7404403|sp|P49849|MUTS_BACSU_3:512 DNA MISMATCH REPAIR PROTEIN MUTS (Bacillus subtilis)
- gi|7448109|pir||C69663 DNA mismatch repair (recognition) mutS - Bacillus subtilis (Bacillus subtilis)
- gi|2634076|emb|CAB13577.1| (Z99112) mutS [Bacillus subtilis] (Bacillus subtilis)
- gi|7379009|emb|CAB83555.1|_4:518 (AL162752) DNA mismatch repair protein [Neisseria meningitidis] (Neisseria meningitidis)
- gi|9106782|gb|AAF84525.1|AE003995_7_39:565 (AE003995) mismatch repair protein [Xylella fastidiosa] (Xylella fastidiosa)
- gi|7189834|gb|AAF38705.1|_5:532 (AE002251) DNA mismatch repair protein MutS [Chlamydophila pneumoniae AR39] (Chlamydophila pneumoniae AR39)
- gi|8979315|dbj|BAA99149.1| (AP002548) DNA mismatch repair [Chlamydophila pneumoniae] (Chlamydophila pneumoniae)
- gi|387849|gb|AAB60711.1|_175:753 (L10319) MutS homologue; major mRNA product contains exon 1a and exon 9b; alternative protein produced from exon 1b and exon 9b [Mus musculus] (Mus musculus)
- gi|400971|sp|P13705|MSH3_MOUSE_175:753 DNA MISMATCH REPAIR PROTEIN MSH3 (REPAIR-3 PROTEIN) (REP-1) (Mus musculus)
- gi|200706|gb|AAA40052.1| (M80360) Citations 2 and 3 contain revisions to the original sequence in Citation 1. The name of the gene was changed after Citation 1 from Rep-1 to Rep-3 to avoid naming conflict with an unrelated gene.; complete cds of major mRNA [Mus musculus] (Mus musculus)
- gi|1083296|pir||JC4019_189:788 DNA mismatch repair protein rep-3 - mouse (Mus musculus)
- gi|3024198|sp|P70755|MUTS_AQUPY_6:518 DNA MISMATCH REPAIR PROTEIN MUTS (Aquifex pyrophilus)
- gi|1619907|gb|AAB16998.1| (U71154) DNA mismatch repair protein [Aquifex pyrophilus] (Aquifex pyrophilus)
- gi|1002520|gb|AAB19235.1|_1:506 (U27343) MutS [Bacillus subtilis] (Bacillus subtilis)
- gi|7387924|sp|Q9Z6W5|MUTS_CHLPN_5:532 DNA MISMATCH REPAIR PROTEIN MUTS (Chlamydophila pneumoniae)
- gi|7448115|pir||G72017 DNA mismatch repair - Chlamydia pneumoniae (strain CWL029) (Chlamydophila pneumoniae)
- gi|4377264|gb|AAD19079.1| (AE001673) DNA Mismatch Repair [Chlamydophila pneumoniae] (Chlamydophila pneumoniae)
- gi|7190210|gb|AAF39048.1|_4:526 (AE002284) DNA mismatch repair protein MutS [Chlamydia muridarum] (Chlamydia muridarum)
- gi|1079288|pir||S53609_19:573 DNA mismatch repair protein MSH2 - African clawed frog (Xenopus laevis)
- gi|3914079|sp|O66652|MUTS_AQUAE_4:518 DNA MISMATCH REPAIR PROTEIN MUTS (Aquifex aeolicus)
- gi|7448111|pir||H70327 DNA mismatch repair protein MutS - Aquifex aeolicus (Aquifex aeolicus)
- gi|2983001|gb|AAC06613.1| (AE000683) DNA mismatch repair protein MutS [Aquifex aeolicus] (Aquifex aeolicus)
- gi|6320302|ref|NP_010382.1|_299:877 Homolog of the human GTBP protein, forms a complex with Msh2p to repair both single-base and insertion-deletion mispairs, redundant with Msh3p in repair of insertion-deletion mispairs; Msh6p (Saccharomyces cerevisiae)
- gi|3024187|sp|Q03834|MSH6_YEAST MUTS PROTEIN HOMOLOG 6 (Saccharomyces cerevisiae)
- gi|1078208|pir||S51246 probable DNA repair protein YDR097c - yeast (Saccharomyces cerevisiae) (Saccharomyces cerevisiae)
- gi|633631|emb|CAA87671.1| (Z47746) probable DNA repair protein [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1588283|prf||2208298A_299:877 MSH6 gene [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1000883|gb|AAB59571.1|_19:529 (L47579) Insertion mutation results in premature stop [Homo sapiens] (Homo sapiens)
- gi|110917|pir||A32495_175:753 rep-1 protein, form A - mouse (Mus musculus)
- gi|6647605|sp|Q9ZDM9|MUTS_RICPR_13:553 DNA MISMATCH REPAIR PROTEIN MUTS (Rickettsia prowazekii)
- gi|7448114|pir||E71685 DNA mismatch repair protein muts (mutS) RP298 - Rickettsia prowazekii (Rickettsia prowazekii)
- gi|3860859|emb|CAA14759.1| (AJ235271) DNA MISMATCH REPAIR PROTEIN MUTS (mutS) [Rickettsia prowazekii] (Rickettsia prowazekii)
- gi|7492209|pir||T41262_362:924 mutS family DNA mismatch repair protein - fission yeast (Schizosaccharomyces pombe) (Schizosaccharomyces pombe)
- gi|3581916|emb|CAA20855.1| (AL031545) mutS family DNA mismatch repair protein msh6 [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|6644186|gb|AAF20943.1|AF207839_1 (AF207839) mismatch repair protein Msh6 [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|6093453|sp|O83348|MUTS_TREPA_5:530 DNA MISMATCH REPAIR PROTEIN MUTS (Treponema pallidum)
- gi|7448112|pir||C71339 probable DNA mismatch repair protein (mutS) - syphilis spirochete (Treponema pallidum subsp. pallidum)
- gi|3322604|gb|AAC65315.1| (AE001212) DNA mismatch repair protein (mutS) [Treponema pallidum] (Treponema pallidum)
- gi|6226648|sp|O04716|MSH6_ARATH_367:977 DNA MISMATCH REPAIR PROTEIN MSH6 (Arabidopsis thaliana)
- gi|7487955|pir||T01508 mismatch repair enzyme T10M13.8 - Arabidopsis thaliana (Arabidopsis thaliana)
- gi|3912921|gb|AAC78699.1| (AF001308) G/T DNA mismatch repair enzyme [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|5763966|emb|CAB53337.1| (AJ245967) mismatch repair protein msh6-1 [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|7268591|emb|CAB80700.1| (AL161493) G/T DNA mismatch repair enzyme [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|8473172|sp|P56883|MUTS_RHIME_21:566 DNA MISMATCH REPAIR PROTEIN MUTS (Sinorhizobium meliloti)
- gi|2104549|gb|AAB57798.1|_372:1015 (AF001535) AGAA.3 [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|4505249|ref|NP_002430.1|_211:789 mutS (E. coli) homolog 3 (Homo sapiens)
- gi|1490521|gb|AAB06045.1| (U61981) hMSH3 [Homo sapiens] (Homo sapiens)
- gi|1000879|gb|AAB59570.1|_19:482 (L47578) The base insertion results in premature stop [Homo sapiens] (Homo sapiens)
- gi|4139230|gb|AAD04176.1|_27:571 (AF109243) mismatch repair protein [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|118951|sp|P20585|MSH3_HUMAN_220:798 DNA MISMATCH REPAIR PROTEIN MSH3 (DIVERGENT UPSTREAM PROTEIN) (DUP) (MISMATCH REPAIR PROTEIN 1) (MRP1) (Homo sapiens)
- gi|106358|pir||A33507 hypothetical protein DUC-1 - human (Homo sapiens)
- gi|181842|gb|AAB47281.1| (J04810) MSH3 [Homo sapiens] (Homo sapiens)
- gi|3914075|sp|O51737|MUTS_BORBU_4:516 DNA MISMATCH REPAIR PROTEIN MUTS (Borrelia burgdorferi)
- gi|7448110|pir||D70199 DNA mismatch repair protein (mutS) homolog - Lyme disease spirochete (Borrelia burgdorferi)
- gi|2688751|gb|AAC67157.1| (AE001179) DNA mismatch repair protein (mutS) [Borrelia burgdorferi] (Borrelia burgdorferi)
- gi|7331984|gb|AAF60672.1|_840:1459 (AC024791) contains similarity to Pfam family PF00488 (DNA mismatch repair proteins, mutS family), score=296.7, E=2.9e-85, N=1 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|7328284|emb|CAB82466.1|_2:419 (Y18631) MutS protein [Staphylococcus aureus] (Staphylococcus aureus)
- gi|1174416|sp|P43248|MSH2_DROME_8:567 DNA MISMATCH REPAIR PROTEIN SPELLCHECKER 1 (Drosophila melanogaster)
- gi|675456|gb|AAA62406.1| (U17893) Spellchecker1 [Drosophila melanogaster] (Drosophila melanogaster)
- gi|3914053|sp|O13396|MSH2_NEUCR_14:562 DNA MISMATCH REPAIR PROTEIN MSH2 (Neurospora crassa)
- gi|2606088|gb|AAB84225.1| (AF030634) DNA mismatch repair protein [Neurospora crassa] (Neurospora crassa)
- gi|7287834|gb|AAF44872.1|AE003406_77_24:571 (AE003416) symbol=spel1; synonym=BG:DS01068.9; cDNA=method:''sim4'', score:''1000.0'', desc:''LD33650 LD Drosophila melanogaster embryo pOT2 Drosophila melanogaster cDNA clone LD33650 5prime, mRNA sequence:AA979275''; match=method:''sim4'', score:''100> (Drosophila melanogaster)
- gi|1076927|pir||S22569_4:572 swi4 protein - fission yeast (Schizosaccharomyces pombe) (Schizosaccharomyces pombe)
- gi|135075|sp|P26359|SWI4_SCHPO_94:664 MATING-TYPE SWITCHING PROTEIN SWI4 (Schizosaccharomyces pombe)
- gi|101087|pir||S21964 swi4 protein - fission yeast (Schizosaccharomyces pombe) (Schizosaccharomyces pombe)
- gi|7492169|pir||T39178 mating-type switching protein swi4 - fission yeast (Schizosaccharomyces pombe) (Schizosaccharomyces pombe)
- gi|5113|emb|CAA43603.1| (X61306) Swi4 [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|5701972|emb|CAB52164.1| (AL109738) mating-type switching protein swi4 [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|7294307|gb|AAF49656.1|_249:858 (AE003532) CG7003 gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|6319935|ref|NP_010016.1|_152:725 mutS homolog, forms a complex with Msh2p to repair insertion-deletion mispairs; redundant with Pms3/Msh6p in repair of insertion-deletion mispairs; Msh3p (Saccharomyces cerevisiae)
- gi|127089|sp|P25336|MSH3_YEAST MUTS PROTEIN HOMOLOG 3 (MISMATCH BINDING PROTEIN) (MBP) (Saccharomyces cerevisiae)
- gi|83266|pir||S19508 MSH3 protein - yeast (Saccharomyces cerevisiae) (Saccharomyces cerevisiae)
- gi|4804|emb|CAA46116.1| (X64954) ORF YCR1152 [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|172004|gb|AAA34803.1| (M96250) MSH3 protein [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1907230|emb|CAA42247.1| (X59720) YCR092c, len:1047 [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|3319876|emb|CAA07684.1|_93:712 (AJ007791) Msh3 protein [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|3914056|sp|O24617|MSH2_ARATH_27:571 DNA MISMATCH REPAIR PROTEIN MSH2 (Arabidopsis thaliana)
- gi|2522362|gb|AAB82649.1| (AF002706) MutS homolog 2 [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|2522364|gb|AAB82650.1| (AF003005) MutS homolog 2 [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|2547236|gb|AAB81282.1| (AF026549) DNA mismatch repair protein MSH2 [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|448278|prf||1916402A_152:724 mismatch repair protein [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|6324482|ref|NP_014551.1|_19:592 MutS homolog encoding major mismatch repair activity in mitosis and meiosis.; Msh2p (Saccharomyces cerevisiae)
- gi|2506880|sp|P25847|MSH2_YEAST DNA MISMATCH REPAIR PROTEIN MSH2 (Saccharomyces cerevisiae)
- gi|1362426|pir||S57379 MSH2 protein - yeast (Saccharomyces cerevisiae) (Saccharomyces cerevisiae)
- gi|600468|emb|CAA58189.1| (X83121) orf 00935 [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1419934|emb|CAA99102.1| (Z74832) ORF YOL090w [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|172002|gb|AAA34802.1|_19:592 (M84170) homologue of bacterial MutS protein [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1000877|gb|AAB59569.1|_19:423 (L47577) mutation causes premature stop [Homo sapiens] (Homo sapiens)
- gi|6166561|sp|O13921|MSH1_SCHPO_50:578 MUTS PROTEIN HOMOLOG 1 (Schizosaccharomyces pombe)
- gi|6224917|gb|AAF06013.1|AF193018_1_255:726 (AF193018) MutS homolog 7 [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|7298155|gb|AAF53392.1|_24:508 (AE003643) spel1 gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|4775576|emb|CAB42554.1|_29:572 (AJ238785) MUS1 protein [Zea mays] (Zea mays)
- gi|9294039|dbj|BAB01996.1|_255:726 (AB020746) DNA repair protein MutS [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|4151103|emb|CAA07342.1|_20:587 (AJ006948) Msh2 [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|7522263|pir||T39832_20:579 dna mismatch repair protein - fission yeast (Schizosaccharomyces pombe) (fragment) (Schizosaccharomyces pombe)
- gi|2894257|emb|CAA17055.1| (AL021839) dna mismatch repair protein [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|7269404|emb|CAB81364.1|_93:725 (AL161563) putative DNA mismatch repair protein [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|4775578|emb|CAB42555.1|_353:805 (AJ238786) MUS2 protein [Zea mays] (Zea mays)
- gi|4775580|emb|CAB42556.1|_46:498 (AJ238787) MUS2 protein [Zea mays] (Zea mays)
- gi|3914062|sp|O65607|MSH3_ARATH_93:725 DNA MISMATCH REPAIR PROTEIN MSH3 (Arabidopsis thaliana)
- gi|7487958|pir||T05793 msh3 protein homolog M7J2.90 - Arabidopsis thaliana (Arabidopsis thaliana)
- gi|2980796|emb|CAA18172.1| (AL022197) putative DNA mismatch repair protein [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|172000|gb|AAA34801.1|_68:557 (M84169) homologue of bacterial MutS protein [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1000875|gb|AAB59568.1|_19:377 (L47576) Frameshift mutation results in premature stop [Homo sapiens] (Homo sapiens)
- gi|6321912|ref|NP_011988.1|_68:557 mutS homolog involved in mitochondrial DNA repair; Msh1p (Saccharomyces cerevisiae)
- gi|730065|sp|P25846|MSH1_YEAST MUTS PROTEIN HOMOLOG 1 (Saccharomyces cerevisiae)
- gi|630277|pir||S48962 MSH1 protein - yeast (Saccharomyces cerevisiae) (Saccharomyces cerevisiae)
- gi|529134|gb|AAB68849.1| (U00059) Yhr120wp [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|3886083|gb|AAC78226.1|_18:547 (AF106587) contains similarity to DNA mismatch repair proteins, mutS (Pfam: PF00488, score=376.5, E=2.8e-109, N=1) [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|9864530|gb|AAG00261.1|_10:607 (AY005798) MSH2 [Trypanosoma cruzi] (Trypanosoma cruzi)
- gi|1000873|gb|AAB59567.1|_19:338 (L47575) premature stop codon due to mutation [Homo sapiens] (Homo sapiens)
- gi|3986757|gb|AAC84154.1|_15:450 (AF109905) MutS homolog [Mus musculus] (Mus musculus)
- gi|7305281|ref|NP_038628.1|_15:450 mut S homolog 5 (E. coli) (Mus musculus)
- gi|5814105|gb|AAD52102.1| (AF107352) MSH5 [Mus musculus] (Mus musculus)
- gi|6409195|gb|AAF07881.1|AF146227_1 (AF146227) MutS homolog 5 [Mus musculus] (Mus musculus)
- gi|7522430|pir||T38256_2:417 muts protein homolog 1 - fission yeast (Schizosaccharomyces pombe) (fragment) (Schizosaccharomyces pombe)
- gi|2330782|emb|CAB11169.1| (Z98559) muts protein homolog 1 [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|8515837|gb|AAF76200.1|_58:505 (AF271389) MSH-5 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|3831701|gb|AAC70065.1|_58:505 (AF070070) MutS homolog [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|4336728|gb|AAD17920.1|_148:585 (AF104243) meiosis-specific MutS homolog [Homo sapiens] (Homo sapiens)
- gi|4505253|ref|NP_002432.1|_44:451 mutS (E. coli) homolog 5 (Homo sapiens)
- gi|3914060|sp|O43196|MSH5_HUMAN MUTS PROTEIN HOMOLOG 5 (Homo sapiens)
- gi|2653649|gb|AAB87632.1| (AF034759) MutS homolog [Homo sapiens] (Homo sapiens)
- gi|3108227|gb|AAC62534.1| (AF048991) MutS homolog 5 [Homo sapiens] (Homo sapiens)
- gi|3831703|gb|AAC70066.1| (AF070071) MutS homolog [Homo sapiens] (Homo sapiens)
- gi|3831715|gb|AAC70067.1| (AF070079) MutS homolog [Homo sapiens] (Homo sapiens)
- gi|4529899|gb|AAD21822.1| (AF134726) MutSH5 [Homo sapiens] (Homo sapiens)
- gi|4505251|ref|NP_002431.1|_148:585 mutS (E. coli) homolog 4 (Homo sapiens)
- gi|3914055|sp|O15457|MSH4_HUMAN MUTS PROTEIN HOMOLOG 4 (Homo sapiens)
- gi|2463653|gb|AAB72039.1| (U89293) MSH4 [Homo sapiens] (Homo sapiens)
- gi|3108220|gb|AAC62533.1|_44:451 (AF048986) MutS homolog 5 [Homo sapiens] (Homo sapiens)
- gi|5725250|emb|CAB52406.1|_44:468 (AJ245661) G7 protein [Homo sapiens] (Homo sapiens)
- gi|6321109|ref|NP_011187.1|_97:543 meiosis specific protein, E.coli MutS protein, localizes to discrete sites on meiotic chromosomes; Msh4p (Saccharomyces cerevisiae)
- gi|1078105|pir||A55201 meiosis-specific protein MSH4 - yeast (Saccharomyces cerevisiae) (Saccharomyces cerevisiae)
- gi|836751|dbj|BAA09235.1| (D50617) MutS protein homolog 4 [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|870825|dbj|BAA08073.1| (D44604) MUST PROTEIN HOMOLOG 4 [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|730066|sp|P40965|MSH4_YEAST_97:543 MUTS PROTEIN HOMOLOG 4 (Saccharomyces cerevisiae)
- gi|563198|gb|AAA65234.1| (U13999) Msh4p [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|3914066|sp|Q19272|MSH5_CAEEL_58:606 MUTS PROTEIN HOMOLOG 5 (Caenorhabditis elegans)
- gi|7498739|pir||T20660 hypothetical protein F09E8.3 - Caenorhabditis elegans (Caenorhabditis elegans)
- gi|3875605|emb|CAA98059.1| (Z73896) Similarity to Yeast DNA mismatch repair protein MSH5 (TR:G836681)~cDNA EST yk16g5.5 comes from this gene~cDNA EST yk16g5.3 comes from this gene~cDNA EST yk353a3.5 comes from this gene~cDNA EST yk583f10.3 comes from this gene~cDNA EST yk583f10.> (Caenorhabditis elegans)
- gi|3914061|sp|O63852|MSHM_SARGL_71:565 MITOCHONDRIAL MUTS PROTEIN HOMOLOG ()
- gi|3132797|gb|AAC16386.1| (AF063191) MSH [Sarcophyton glaucum] ()
- gi|5815430|gb|AAD52669.1|AF178755_1_50:495 (AF178755) HIM-14 protein [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|5921981|gb|AAB93433.2| (U58758) C. elegans HIM-5 (GB:AF178755); contains similarity to Pfam domain PF00488 (mutS), Score=204.6, E-value=4.9e-58, N=1 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|7012942|gb|AAF35250.1|AF227632_1_1:276 (AF227632) mismatch binding protein Mus3 [Zea mays] (Zea mays)
- gi|6981224|ref|NP_034959.1|_143:376 mutS homolog 3 (E. coli) (Mus musculus)
- gi|110915|pir||B32495 Rep-1 protein B - mouse (Mus musculus)
- gi|200704|gb|AAA40051.1| (M24919) complete cds of class B 1.6 kb mRNA [Mus musculus] (Mus musculus)
- gi|387848|gb|AAB60710.1| (L10319) alternate protein including exons 1b and 9a [Mus musculus] (Mus musculus)
- gi|7243293|dbj|BAA92687.1|_38:229 (AB039965) mismatch repair system component MutS [Pseudomonas putida] (Pseudomonas putida)
- gi|7547005|gb|AAF63754.1|AF242852_1_65:256 (AF242852) DNA mismatch repair protein [Brassica napus] (Brassica napus)
- gi|6320047|ref|NP_010127.1|_53:531 MutS homolog involved in chromosome exchange; Msh5p (Saccharomyces cerevisiae)
- gi|2497997|sp|Q12175|MSH5_YEAST MUTS PROTEIN HOMOLOG 5 (Saccharomyces cerevisiae)
- gi|2132350|pir||S67702 MSH5 protein - yeast (Saccharomyces cerevisiae) (Saccharomyces cerevisiae)
- gi|836681|gb|AAA67649.1| (L42517) MSH5 [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1321950|emb|CAA66337.1| (X97751) D1542 [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1431243|emb|CAA98728.1| (Z74202) ORF YDL154w [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|1582703|prf||2119252A_48:531 MSH5 gene [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|2072992|gb|AAC46142.1|_1:130 (U95756) DNA mismatch repair protein [Synechococcus PCC7942] (Synechococcus PCC7942)
- gi|7490460|pir||T37626_49:190 DNA mismatch repair protein homolog - fission yeast (Schizosaccharomyces pombe) (fragment) (Schizosaccharomyces pombe)
- gi|2408012|emb|CAB11774.1| (Z99091) muts protein homolog; DNA mismatch repair protein [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)

              10             20        30            40         50     
              |              |         |             |          |     
   1 MEGMLKGEGPGPLPPL.....LQQYVELRDQYPDYLLLFQVGD....FYECFG.EDAERLARALG
   2 --GMLKGEGPGPLPPL.....LQQYVELRDQYPDYLLLFQVGD....FYECFG.EDAERLARALG
   3 --------NFDAHTPM.....MQQYLKLKAQHPEILLFYRMGD....FYELFY.DDAKRASQLLD
   4 --------NFDAHTPM.....MQQYLRLKAQHPEILLFYRMGD....FYELFY.DDAKRASQLLD
   5 --------NFDAHTPM.....MQQYLKLKAQHPEILLFYRMGD....FYELFY.DDAKRASQLLD
   6 -EGMLKGEGPGPLPPL.....LQQYVELRDRYPDYLLLFQVGD....FYECFG.EDAERLARALG
   7 -EGMLKGEGPGPLPPL.....LQQYVELRDRYPDYLLLFQVGD....FYECFG.EDAERLARALG
   8 -----SEENFQQHTPM.....MQQYLKLKAENPDILLFYRMGD....FYELFY.DDAKKAAALLD
   9 --------SLSQHTPM.....MQQYWKLKREHPDQLMFYRMGD....FYELFY.EDAKKAAKLLD
  10 ---------LSQHTPM.....MQQYFKLKHQHPDQLMFYRMGD....FYELFY.EDAKKAAKLLD
  11 ---------LSQHTPM.....MQQYFKLKHQHPDQLMFYRMGD....FYELFY.EDAKKAAKLLD
  12 ----SPSESLSHHTPM.....MQQYLRLKAENPDILLFYRMGD....FYELFY.DDAKRASELLD
  13 ----------PPLPPL.....LQQYVELRDRYPDYLLLFQVGD....FYECFG.EDAERLARALG
  14 -------KDFSNHTPM.....MQQYLKLKAQHPEILLFYRMGD....FYELFY.DDAKRASQLLD
  15 --VMLKGEGPGPLPPL.....LQQYVELRDRYPDYLLLFQVGD....FYECFG.EDAERLARALG
  16 ------------VTPL.....MEQYLRIKEQYKDSILLFRLGD....FYEAFF.EDAKIVSKVLN
  17 ---------------F.....VRFFQGMPEKPTTTVRLFDRGD....FYTAHG.EDALLAAREVF
  18 ---------------F.....VRFFQGMPEKPTTTVRLFDRGD....FYTAHG.EDALLAAREVF
  19 ---------------F.....VRFFQGMPEKPTTTVRLFDRGD....FYTAHG.EDALLAAREVF
  20 ------------VTPL.....MEQYLRIKEQYKDSILLFRLGD....FYEAFF.EDAKIVSKVLN
  21 ---------RQKLTPM.....FQHYTEVKEQYQGALLLYRVGD....FFECFF.QDAVIIARELE
  22 ---------RQKLTPM.....FQHYTEVKEQYQGALLLYRVGD....FFECFF.QDAVIIARELE
  23 ---------------F.....VRFFEGMPEKPSTTVRLFDRGD....FYTAHG.EDALLAAREVF
  24 ---------------F.....VRFFEGMPEKPSTTVRLFDRGD....FYTAHG.EDALLAAREVF
  25 STLYVPEDFLNSCTPG.....MRKWWQIKSQNFDLVICYKVGK....FYELYH.MDALIGVSELG
  26 STLYVPEDFLNSCTPG.....MRKWWQIKSQNFDLVICYKVGK....FYELYH.MDALIGVSELG
  27 STLYVPEDFLNSCTPG.....MRKWWQIKSQNFDLVICYKVGK....FYELYH.MDALIGVSELG
  28 STLYVPEDFLNSCTPG.....MRKWWQIKSQNFDLVICYKVGK....FYELYH.MDALIGVSELG
  29 -------KDFSNHTPM.....MQQYLKLKAQHPEILLFYRMGD....FYELFY.DDAKRASQLLD
  30 TTLYVPEEFLNSCTPG.....MRKWWQLKSQNFDLVIFYKVGK....FYELYH.MDAVIGVSELG
  31 ---------------F.....VRFFEGMPEKPSTTVGLFDRGD....FYTAHG.EDALLAAREVF
  32 STLYVPEDFLNSCTPG.....MRKWWQIKSQNFDLVICYKVGK....FYELYH.MDALIGVSELG
  33 TTLYVPEEFLNSCTPG.....MRKWWQLKSQNFDLVIFYKVGK....FYELYH.MDAVIGVSELG
  34 ----------EKLSPG.....MQQYVDIKKQYPDAFLLFRMGD....FYELFY.EDAVNAAQILE
  35 -----------KLTPM.....MQQWHQCKEQAGDCLLLFRLGE....FYEAFF.DDALILAQNLD
  36 ----------SAVSPM.....MQQYLGIKAQHTDKLVFYRMGD....FYEMFF.DDAVEAAKLLD
  37 -----------GYTPM.....IQQYLKIKAEHQDAFLFFRLGD....FYEMFF.EDAKKASQELE
  38 ----------SAVSPM.....MQQYLGIKAQHTDKLVFYRMGD....FYEMFF.DDAVEAAKLLD
  39 --KPEGGKGMAEHTPL.....MKQYFAAKAEYPDLLLFFRMGD....FYELFH.QDARKAARLLD
  40 -----------KPTPM.....MEQWHQCKEKAGDSVLLFRMGD....FYEAFY.DDAVLLSQHLE
  41 DCKPFNKRSKSVYTPL.....ELQYLDMKQQHKDAVLCVECGY....KYRFFG.EDAEIAARELN
  42 DCKPFNKRSKSVYTPL.....ELQYLDMKQQHKDAVLCVECGY....KYRFFG.EDAEIAARELN
  43 DCKPFNKRSKSVYTPL.....ELQYLDMKQQHKDAVLCVECGY....KYRFFG.EDAEIAARELN
  44 ----------KELTPM.....LAQYHQFKSMYPDCLLLFRLGD....FYELFY.EDAVVGSKELG
  45 ---------------M.....IQQYLKIKAEHQDAFLFFRLGD....FYEMFF.EDAKKASQELE
  46 -----------KPTPM.....MEQWHQCKEKAGDSVLLFRMGD....FYEAFY.DDAVLLSQHLE
  47 -----------KLTPM.....MQQWHQCKEQAGDCLLLFRLGE....FYEAFF.DDALVLAQNLD
  48 ---------------F.....LHFYQSMPEKPDTTVRVFDRND....YYTVHG.GDALFAAKEVF
  49 --------SEKELTPM.....LSQYHYFKNQYPDCLLLFRLGD....FYELFY.EDAYIGSKELG
  50 RTLYIPSSAWNKFTPF.....EKQYWEIKSKMWDCIVFFKKGK....FFELYE.KDALLANALFD
  51 RTLYIPSSAWNKFTPF.....EKQYWEIKSKMWDCIVFFKKGK....EFELYE.KDALLANALFD
  52 ---------------F.....VRFFQGMPEKPTTTVRLFDRGD....FYTAHG.EDALLAAREVF
  53 DCKPFNKRSKSVYTPL.....ELQYLDMKQQHKDAVLCVECGY....KYRFFG.EDAEIAARELN
  54 -----QKYNYNVATKM.....MQQYLDIKFAHLDCLLLFRMGD....FYELFY.EDAILASNILG
  55 RTLYIPPSAWATFKPF.....EKQFWKIKKDLMDTVVFFQKGK....FYELYE.NDAAIGHQVFS
  56 ----------ASDTPL.....MRQYHAIRAQHPDAVLFFRLGD....FYEMFD.SDALHVSTLLG
  57 RTLYLPPDFVKKLTGG.....QRQWWEFKAKHMDKVVFFKMGK....FYELFE.MDAHVGAKELD
  58 ----ASEESRSTATPM.....MEQFIEIKANNPDSLLFYRMGD....FYELFF.QDAVEASRALG
  59 RTLYLPPDFVKKLTGGqv...8gnLRQWWEFKAKHMDKVVFFK....MGKFYE.LFEMDAHVGAK
  60 ---SANKRSKSIYTPL.....ELQYIEMKQQHKDAVLCVECGY....KYRFFG.EDAEIAARELN
  61 ---------------F.....VRFFQGMPEKPTTTVRLFDRGD....FYTAHG.EDALLAAREVF
  62 ----------------.....---FYKTLPNDTRAVRFFDRKD....YYTAHG.ENSVFIAKTYY
  63 ---SANKRSKSIYTPL.....ELQYIEMKQQHKDAVLCVECGY....KYRFFG.EDAEIAARELN
  64 -----------NVTPM.....IRQYLDIKKKYKDAVLFFRVGS....FYEMFF.DDAIEVSKLLN
  65 KTLWVPPDFHQKQTPG.....HRQWWTMKSQHFDTILLFKVGK....FYETYH.MDAVEVVRALN
  66 ----------SNVTPM.....MQQYLKIKSEYQDCLLFFRLGD....FYEMFY.EDAKEASRVLE
  67 ---TYPEYGHKCASNF.....IKFHAKLGEKPATTVRFFDHTD....RYTVHGsDDCELVAKIVY
  68 --------------GF.....IRFYKSLPQLGEEAIRIFDRGD....WYTAHG.DDATFIARTVY
  69 ---------------F.....IKFHAKLGEKPATTVRFFDHTD....RYTVHGsDDCELVAKIVY
  70 -----PTKQKSVFTPL.....EQQYLELKKNYQETILAIEVGY....KFRFFG.KDAKIASEVLG
  71 ---SKPTKQKSVFTPL.....EQQYLELKKNYQETILAIEVGY....KFRFFG.KDAKIASEVLG
  72 STLHVPEKFLNGLSPG.....VRQWWVLKSDNYDCVLFFKVGK....FYELYH.MDADVGVNELG
  73 ---KARKSPTAKLTPL.....DKQVKDLKMHHRDKVLVIRVGY....KYKCFA.EDAVTVSRILH
  74 -EYVPETSSSRKYTPL.....EQQVVELKSKYPDVVLMVEVGY....RYRFFG.EDAEIAARVLG
  75 ----------------.....---FYKTLPNDTRAVRFFDRKD....YYTAHG.ENSVFIAKTYY
  76 ---KARKSPTAKLTPL.....DKQVKDLKMHHRDKVLVIRVGY....KY-CFA.EDAVTVSRILH
  77 ---------------F.....YKKYTGLPKKPLKTIRLVDKGD....YYTVIG.SDAIFVADSVY
  78 ---------------F.....YKKYTGLPKKPLKTIRLVDKGD....YYTVIG.SDAIFVADSVY
  79 ---------------F.....VRFFQGMPEKPTTTVRLFDRGD....FYTAHG.EDALLAAREVF
  80 --DFIRPKEKVTLPPL.....LKEVSFQQKKFADCVLLTKVGN....FYEMYF.EQAEKIGPLLN
  81 KTLHIPPDVFKKMSAS.....QKQYWSVKSEYMDIVLFFKVGK....FYELYE.LDAELGHKELD
  82 ---------------F.....IKFHAKLGEKPATTVRFFDHTD....RYTVHGsDDCELVAKIVY
  83 ----------------.....---FFKKLPQDPRAVRLFDRRD....YYTAHG.ENATFIARTYY
  84 KTLHIPPDVFKKMSAS.....QKQYWSVKSEYMDIVLFFKVGK....FYELYE.LDAELGHKELD
  85 ----------------.....--NFYEKMPKDTNTVRVFDRGE....FYVAIG.EDASFVAQNAY
  86 ----------------.....--NFYEKMPKDTNTVRVFDRGE....FYVAIG.EDASFVAQNAY
  87 -EYVPETSSSRKYTPL.....EQQVVELKSKYPDVVLMVEVGY....RYRFFG.EDAEIAARVLG
  88 STLFIPPDALRKMSTS.....QKQYWNIKCKYMDVVLFFKVGK....FYELYE.LDAEIGQKELD
  89 STLFIPPDALRKMSTS.....QKQYWNIKCKYMDVVLFFKVGK....FYELYE.LDAEIGQKELD
  90 -EYVPETSSSRKYTPL.....EQQVVELKSKYPDVVLMVEVGY....RYRFFG.EDAEIAARVLG
  91 -KLSSTEPSKASLPPS.....LQYVRDLMDLYKDHVVLTQMGS....FYELYF.EQAIRYAPELN
  92 ---------------F.....VRFFQGMPEKPTTTVRLFDRGD....FYTAHG.EDALLAAREVF
  93 -KLSSTEPSKASLPPS.....LQYVRDLMDLYKDHVVLTQMGS....FYELYF.EQAIRYAPELN
  94 ----------------.....-------KSKSPNTIAIFSRGE....YFSVYG.DDATFVATNIF
  95 ----------------.....LQAFTAVGGDDKACVRLFSRGGstpgCYVLGS.WAGFIAREYIR
  96 ---------------F.....VRFFQGMPEKPTTTVRLFDRGD....FYTAHG.EDALLAAREVF
  97 ----------------.....----------------------....------.-----------
  98 ----------------.....----------------------....------.-----------
  99 ----------------.....----------------------....------.-----------
 100 ----------------.....----------------------....------.-----------
 101 ----------------.....----------------------....------.-----------
 102 ----------------.....----------------------....------.-----------
 103 ----------------.....----------------------....------.-----------
 104 ----------------.....----------------------....------.-----------
 105 ----------------.....----------------------....------.-----------
 106 ----------------.....----------------------....------.-----------
 107 ----------------.....----------------------....------.-----------
 108 ----------------.....----------------------....------.-----------
 109 ----------------.....----------------------....------.-----------
 110 ----------------.....----------------------....------.---EQVASLLD
 111 ----------------.....----------------------....------.-----------
 112 ----------------.....----------------------....------.-----------
 113 DCKPFNKRSKSVYTPL.....ELQYLDMKQQHKDAVLCVECGY....KYRFFG.EDAEIAARELN
 114 ----------------.....----------------------....------.-----------
 115 -----------KYTPL.....EQQVVELKRKHPDVILMVEVGY....RYRFFG.EDAEIAARVLG
 116 ----------------.....----------------------....------.-----------
 117 ----------------.....----------------------....------.-----------
 118 ----------------.....----------------------....---CFF.QDAIVVARELE
 119 -LDFIRPKEKVTLPPL.....LKEVSFQQKKFADCVLLTKVGN....FYEMYF.EQAEKIGPLLN


              60               70        80           90       100     
              |                |         |            |         |     
   1 L.....VLTHK.....TSK..DFTTPMAGIPLRAFEAYAE.RLL..KMGFRLAVADQVEPA...E
   2 L.....VLTHK.....TSK..DFTTPMAGIPLRAFEAYAE.RLL..KMGFRLAVADQVEPA...E
   3 I.....SLTKR.....GASa.GEPIPMAGIPYHAVENYLA.KLV..NQGESVAICEQIGDP...A
   4 I.....SLTKR.....GASa.GEPIPMAGIPYHAVENYLA.KLV..NQGESVAICEQIGDP...A
   5 I.....SLTKR.....SASa.GEPIPMAGIPYHAVENYLA.KLV..NQGESVAICEQIGDP...A
   6 L.....VLTHK.....TSK..DFTTPMAGIPIRAFDAYAE.RLL..KMGFRLAVADQVEPA...E
   7 L.....VLTHK.....TSK..DFTTPMAGIPIRAFDAYAE.RLL..KMGFRLAVADQVEPA...E
   8 I.....SLTKR.....GQSa.GQPIPMAGMPYHAVEGYLA.KLV..QLGESVAICEQIGDP...T
   9 I.....TLTAR.....GQSa.GKSIPMAGIPFHSVEGYLA.KLV..KLGESVAICEQIGDP...A
  10 I.....TLTAR.....GQSg.GKAIPMAGIPFHSAEGYLA.KLV..KLGESVAICEQIGDP...A
  11 I.....TLTAR.....GQSg.GKAIPMAGIPFHSAEGYLA.KLV..KLGESVAICEQIGDP...A
  12 I.....SLTKR.....GASa.GEPIPMAGVPFHAVEGYLA.KLV..QMGESVAICEQIGDP...A
  13 L.....VLTHK.....TSK..DFTTPMAGIPIRAFDAYAE.RLL..KMGFRLAVADQVEPA...E
  14 I.....SLTKR.....GASa.GEPIPMAGIPHHAVENYLA.KLV..NQGESVAICEQIGDP...A
  15 L.....VLTHK.....TSK..DFTTPMAGIPIRAFDAYAE.RLL..RMGFGLAVADQVEPA...E
  16 I.....VLTRR.....---..-QDAPMAGIPYHALNTYLK.KLV..EAGYKVAICDQMEEP...S
  17 K.....TQGVIkymg.PAG..AKNLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNRAG-...N
  18 K.....TQGVIkymg.PAG..AKNLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNRAG-...N
  19 K.....TQGVIkymg.PAG..AKNLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNRAG-...N
  20 I.....VLTRR.....---..-QDAPMAGIPYHALNTYLK.KLV..EAGYKVAICDQMEEP...S
  21 L.....ILTSK.....EGGkeIGRVAMTGVPHHALDRYAR.QLV..EKGYAVAICDQVEDA...A
  22 L.....ILTSK.....EGGkeIGRVAMTGVPHHALDRYAR.QLV..EKGYAVAICDQVEDA...A
  23 K.....TQGVIkymg.PAG..SKTLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNKAG-...N
  24 K.....TQGVIkymg.PAG..SKTLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNKAG-...N
  25 L.....VFMKG.....---..--NWAHSGFPEIAFGRYSD.SLV..QKGYKVARVEQTETP...E
  26 L.....VFMKG.....---..--NWAHSGFPEIAFGRYSD.SLV..QKGYKVARVEQTETP...E
  27 L.....VFMKG.....---..--NWAHSGFPEIAFGRYSD.SLV..QKGYKVARVEQTETP...E
  28 L.....VFMKG.....---..--NWAHSGFPEIAFGRYSD.SLV..QKGYKVARVEQTETP...E
  29 I.....SLTKR.....GASa.GEPIPMAGIPHHAVENYLA.KLV..NQGESVAICEQIGDP...A
  30 L.....IFMKG.....---..--NWAHSGFPEIAFGRFSD.SLV..QKGYKVARVEQTETP...E
  31 K.....TQGVIkymg.PAG..AKTLQTVVLSKMNFESFVK.DLLl.VRHYRVEVYKNKAG-...N
  32 L.....VFMKG.....---..--NWAHSGFPEIAFGRYSD.SLV..QKGYKVARVEQTETP...E
  33 L.....IFMKG.....---..--NWAHSGFPEIAFGRFSD.SLV..QKGYKVARVEQTETP...E
  34 I.....SLTSR.....NKNa.DNPIPMAGVPYHSAQQYID.VLI..EQGYKVAIAEQMEDP...K
  35 I.....TLTQR.....---..-QNVPMSGIPATCLDGYVD.RLV..SRGFKVAIAEQADNT...E
  36 I.....TLTTRg....QVD..GEPVKMAGVPFHAAEQYLA.RLV..KLGKSVAICEQVGEV...G
  37 I.....TLTSR.....DGGa.AEKIPMCGVPYHSASAYIE.QLI..KKGYKVAICEQTEDP...K
  38 I.....TLTTRg....QVD..GEPVKMAGVPFHAAEQYLA.RLV..KLGKSVAICEQVGEV...G
  39 I.....TLTQR.....GSSg.GAPIPMAGVPVHAYEGYLA.RLI..ALGESVAICEQIGDP...G
  40 L.....TLTQR.....---..-QGIPMSGIPVSTVDTYVD.RLI..GKGFKVAVAEQFGEP...A
  41 I.....YCHLD.....---..-HNFMTASIPTHRLFVHVR.RLV..AKGYKVGVVKQTETA...A
  42 I.....YCHLD.....---..-HNFMTASIPTHRLFVHVR.RLV..AKGYKVGVVKQTETA...A
  43 I.....YCHLD.....---..-HNFMTASIPTHRLFVHVR.RLV..AKGYKVGVVKQTETA...A
  44 L.....VLTSRpa...GKG..RERIPMCGVPYHSANNYIA.KLV..NKGYKVAICEQVEDP...S
  45 I.....TLTSR.....DGGa.AEKIPMCGVPYHSASAYIE.QLI..KKGYKVAICEQTEDP...K
  46 L.....TLTQR.....---..-QGIPMSGIPVSTVDTYVD.RLI..GKGFKVAVAEQFGEP...A
  47 I.....TLTQR.....---..-QNIPMSGIPAAYLDGYVD.RLV..SRGFKIAIAEQADNS...E
  48 K.....TNGVIkyl..GSG..NKKLESVVLSKMNFESVVK.DLLl.VRQYRVEVYKNKSG-...G
  49 L.....VLTSRpa...GKG..KERIPMCGVPYHSANSYIA.KLV..NKGYKVAICEQVEDP...S
  50 L.....KIAGG.....--G..RANMQLAGIPEMSFEYWAA.QFI..QMGYKVAKVDQRESM...L
  51 L.....KIAGG.....--G..RANMQLAGIPEMSFEYWAA.QFI..QMGYKVAKVDQRESM...L
  52 K.....TQGVIkymg.PAG..AKNLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNRAG-...N
  53 I.....YCHLD.....---..-HNFMTASIPTHRLFVHVR.RLV..AKGYKVGVVKQTETA...A
  54 I.....ALTKR.....GKNc.EEEIPMCGVPYHALEHYLT.KLI..EENYKVAICDQLETP...E
  55 L.....KLTDR.....---..-VNMKMVGIPEASFDYWAS.QFI..AKGYRIARVDQLETA...L
  56 L.....TLTKR.....---..-NGTPMCGVPVHTARTHIA.RLL..KHGKKVALCEQVSHP...-
  57 I.....QYMKG.....---..--EQPHCGFPEKNFSVNIE.KLV..RKGYRVLVVEQTETP...D
  58 I.....TLTKR.....GQHm.GQEIPMCGVPVHAADDYLQ.KLI..ASGYRVAVCEQVEDP...A
  59 E.....LDIQY.....MKG..-----EQPHCGFPEKNFSV.NIE..KLVRKGYRVLVVEQT...E
  60 I.....YCHLD.....---..-HNFMTASIPTHRLFVHVR.RLV..AKGYKVGVVKQTETA...A
  61 K.....TQGVIkymg.PAG..AKNLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNRAG-...N
  62 H.....TTTALrql..GSG..SNALSSVSISRNMFETIAR.DLLleRNDHTVELYEGSGS-...-
  63 I.....YCHLD.....---..-HNFMTASIPTHRLFVHVR.RLV..AKGYKVGVVKQTETA...A
  64 L.....TLTKR.....---..-ENVPMCGVPYHTSKEYIR.KLI..LFDKKVAICEQASN-...S
  65 I.....AFMRG.....---..--SYAHAGFPEHAASKFAD.QLM..NHGYKVARIEQTETP...Q
  66 I.....TLTKR.....DAKk.ENPIPMCGVPYHSADSYID.TLV..NNGYKVAICEQMEDP...K
  67 K.....STAFIgallpDDK..KETLQFVSMSKGNFELAVR.ELLl.VRNYRVEVY------...-
  68 K.....TTSVIrqlg.RSD..HTGLPSVTMTVTVFRQFLR.EALf.KLGKRIEIW------...A
  69 K.....STAFIgallpDDK..KETLQFVSMSKGNFELAVR.ELLl.VRNYRVEVY------...-
  70 I.....SCYFE.....---..-HNFLNASVPSYRIDYHLE.RLI..NFGLKVAVVRQTETA...A
  71 I.....SCYFE.....---..-HNFLNASVPSYRIDYHLE.RLI..NFGLKVAVVRQTETA...A
  72 F.....TYMRG.....---..--EFAHSGFPEISFDKMST.ILV..DRGFKVARVEQTETP...D
  73 I.....KLVPGk....10pq.DCNHRQFAYCSFPDVRLNV.HLE..RLVHHNLKVAVVEQA...E
  74 I.....YAHMD.....---..-HNFMTASVPTFRLNFHVR.RLV..NAGYKIGVVKQTETA...A
  75 H.....TTTALrql..GSG..SNALSSVSISRNMFETIAR.DLLleRNDHTVELYEGSGS-...-
  76 I.....KLVPGk....10pq.DCNHRQFAYCSFPDVRLNV.HLE..RLVHHNLKVAVVEQA...E
  77 H.....TQSVLk....10ta.KNFHEPTKYVTVSLQVLAT.LLKl.CLLDLGYKVEIYDK-...-
  78 H.....TQSVLk....10ta.KNFHEPTKYVTVSLQVLAT.LLKl.CLLDLGYKVEIYDK-...-
  79 K.....TQGVIkymg.PAG..AKNLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNRAG-...N
  80 L.....RVSKK.....KTS..KSDVSMAGFPFFKLDRYLK.ILVe.DLKKCVALSEEVIRPvddL
  81 W.....KMTMS.....GV-..-GKCRQVGISESGIDEAVQ.KLL..ARGYKVGRIEQLETS...D
  82 K.....STAFIgallpDDK..KETLQFVSMSKGNFELAVR.ELLl.VRNYRVEVY------...-
  83 H.....TMSALrql..GSS..SDGILSASVSKAMFETIAR.NILleRTDCTLELYEGSGS-...-
  84 W.....KMTMS.....GV-..-GKCRQVGISESGIDEAVQ.KLL..ARGYKVGRIEQLETS...D
  85 H.....TTSVL.....KHHn.VSNTSYCNLSPSLFIKFAE.DVLs.NLAKRVEIW------...G
  86 H.....TTSVL.....KHHn.VSNTSYCNLSPSLFIKFAE.DVLs.NLAKRVEIW------...G
  87 I.....YAHMD.....---..-HNFMTA------------.---..--GYKIGVVKQTETA...A
  88 W.....KMTVS.....GV-..-GKCRQVGISESGIDDAVD.KLI..ARGYKVGRIEQMESA...N
  89 W.....KMTVS.....GV-..-GKCRQVGISESGIDDAVD.KLI..ARGYKVGRIEQMESA...N
  90 I.....YAHMD.....---..-HNFMT-------------.---..-ARYKIGVVKQTETA...A
  91 I.....SLTNR.....AYS..HGKVPFAGFPVHQLSRHLK.MLVn.NCGYSVTIAEQFKKK...D
  92 K.....TQGVIkymg.PAG..AKNLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNRAG-...N
  93 I.....SLTNR.....AYS..HGKVPFAGFPVHQLSRHLK.MLVn.NCGYSVTIAEQFKKK...D
  94 Ksd...6vkTF.....TLS..TDNSQQMKYISVNRGQYEK.VVRe.TIVLLRCSVELY---...-
  95 S.....TAVLK.....NWG..GVDVVVVNDS-IAKEVIRD.CLL..RRGASVEYYER----...-
  96 K.....TQGVIkymg.PAG..AKNLQSVVLSKMNFESFVK.DLLl.VRQYRVEVYKNRAG-...N
  97 -.....-----.....-GP..RSGIPSASFPSPQP-----.---..---------------...-
  98 -.....-----.....-GP..RSGIPSASFPSPQP-----.---..---------------...-
  99 -.....-----.....---..-------------------.---..---------------...-
 100 -.....-----.....---..-------------------.---..---------------...-
 101 -.....-----.....---..-------------------.---..---------------...-
 102 -.....-----.....---..-------------------.---..---------------...-
 103 -.....-----.....---..-------------------.---..---------------...-
 104 -.....-----.....---..-------------------.---..---------------...-
 105 -.....-----.....---..-------------------.---..---------------...-
 106 -.....-----.....---..-------------------.---..---------------...-
 107 -.....-----.....---..-------------------.---..---------------...-
 108 -.....-----.....---..-------------------.---..---------------...-
 109 -.....-----.....---..-------------------.---..---------------...-
 110 M.....KIISL.....--G..KRSLLQMGFPVYSLTTHLS.TLL..DKGWTVIVIDELVTN...-
 111 -.....-----.....---..-------------------.---..---------------...-
 112 -.....-----.....---..-------------------.---..---------------...-
 113 I.....YCHLD.....---..-HNFMTASIPTHRLFVHVR.RLV..AKGYKVGVVKQTETA...A
 114 -.....-----.....---..-------------------.---..---------------...-
 115 I.....YAHMD.....---..-HSFMTASVPTFRLNVHVR.GLV..NAGYKVGVVKQTETA...A
 116 -.....-----.....---..-------------------.---..---------------...-
 117 -.....-----.....---..-------------------.---..---------------...-
 118 L.....VLTSK.....EAGkeVGRVPMAGIPYHALDRYAS.QLV..EKGYAIAICDQVETA...A
 119 L.....RVSKK.....KTS..KSDVSMAGFPFFKLDRYLK.ILVe.DLKKCVALSEEVIRPvddL


                110       120                   130            140     
                 |         |                     |              |     
   1 EAE.....GLVRREVTQLLTPGTLLQ....ESLL...P.....REANYLAAIA.....TGDG...
   2 EAE.....GLVRREVTQLLTPGTLLQ....ESLL...P.....REANYLAAIA.....TGDG...
   3 TSK.....GPVERKVVRIVTPGTISD....EALLq..E.....RQDNLLAAIWq....DSKG...
   4 TSK.....GPVERKVVRIVTPGTISD....EALLq..E.....RQDNLLAAIWq....DSKG...
   5 TSK.....GPVERKVVRIVTPGTISD....EALLq..E.....RQDNLLAAIWq....DSKG...
   6 EAE.....GLVRREVTQLLTPGTLTQ....EALL...P.....REANYLAAIA.....TGDG...
   7 EAE.....GLVRREVTQLLTPGTLTQ....EALL...P.....REANYLAAIA.....TGDG...
   8 TSK.....GPVERQIVRIVTPGTVSD....EALLp..E.....RQDNLIAAVYq....EKEK...
   9 TTK.....GPVERQVVRIITPGTVSD....EALLd..E.....RRDNLLAAVVg....DERL...
  10 TSK.....GPVERQVVRIITPGTVSD....EALLd..E.....RRDNLLAAILg....DERL...
  11 TSK.....GPVERQVVRIITPGTVSD....EALLd..E.....RRDNLLAAILg....DERL...
  12 TSK.....GPVERKVVRIVTPGTVTD....EALLs..E.....RVDNLIAAIYh....HNGR...
  13 EAE.....GLVRREVTQLLTPGTLTQ....EALL...P.....REANYLAAIA.....TGDG...
  14 TSK.....GPVERKVVRIVTPGTISD....EALLq..E.....RQDNLLAAIWq....DGKG...
  15 EAE.....GLVRREVTQLLTPGTLTQ....EALL...P.....REANYLAAIA.....TGDG...
  16 KSK.....KLIRREVTRVVTPGSIVE....DEFL...S.....ETNNYMAVVSe....EKGR...
  17 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMSASIGv....10vd...
  18 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMSASIGv....10vd...
  19 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMSASIGv....10vd...
  20 KSK.....KLIRREVTRVVTPGSIVE....DEFL...S.....ETNNYMAVVSe....EKGR...
  21 EAQaek..RMVERQVTKLLTPGTLTD....DSMLp..A.....KRNNFLAAIAm....VEDK...
  22 EAQaek..RMVERQVTKLLTPGTLTD....DSMLp..A.....KRNNFLAAIAm....VEDK...
  23 KAS.....KENEWYLAFKASPGNLSQf...EDIL...F.....GNNDMSASVGv....10vd...
  24 KAS.....KENEWYLAFKASPGNLSQf...EDIL...F.....GNNDMSASVGv....10vd...
  25 MMEa....13ydRVVRREICRIITKG....TQTYsvle.....GDPSENYSKY.....LLSL...
  26 MMEa....13ydRVVRREICRIITKG....TQTYsvle.....GDPSENYSKY.....LLSL...
  27 MMEa....13ydRVVRREICRIITKG....TQTYsvle.....GDPSENYSKY.....LLSL...
  28 MMEa....13ydRVVRREICRIITKG....TQTYsvle.....GDPSENYSKY.....LLSL...
  29 TSK.....GPVERKVVRIVTPGTISD....EALLq..E.....RQDNLLAAIWq....DGKG...
  30 MMEa....13fdRVVRREICRIITKG....TQTYsvld.....GDPSENYSRY.....LLSL...
  31 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMATSIGi....10vd...
  32 MMEa....13ydRVVRREICRIITKG....TQTYsvle.....GDPSENYSKY.....LLSL...
  33 MMEa....13fdRVVRREICRIITKG....TQTYsvld.....GDPSENYSRY.....LLSL...
  34 QAV.....GVVKREVVQVITPGTVVD....SSKP...D.....SQNNFLVSIDr....EGNQ...
  35 GSK.....GLVPRTINRLITPGALLS....SSLLp..E.....KANNYVLAINq....VGSL...
  36 AGK.....GPVERKVVRIVTPGTLTD....SALLe..D.....KETNRIVAVSp....DKKY...
  37 AAK.....GVVKREVVQLITPGTVMD....GKGIh..E.....SENNFIASVSa....CSNG...
  38 AGK.....GPVERKVVRIVTPGTLTD....SALLe..D.....KETNRIVAVSp....DKKY...
  39 LAK.....GLVERKVVRIVTPGTITD....EVLLe..E.....RRDTLLMALSr....SKNC...
  40 KEKeskkiGPMARDIQRFVTPGTLLS....STLLq..E.....KFNNYIVAINr....IGSL...
  41 LKAig...6ksSVFSRKLTALYTKST....LIGE...D.....VNPl16tdTS.....TNYL...
  42 LKAig...6ksSVFSRKLTALYTKST....LIGE...D.....VNPl16tdTS.....TNYL...
  43 LKAig...6ksSVFSRKLTALYTKST....LIGE...D.....VNPl16tdTS.....TNYL...
  44 KAK.....GIVKRDVIRVITPGTFFE....----...-.....RETGGLCSLYr....KGKS...
  45 AAK.....GVVKREVVQLITPGTVMD....GKGIh..E.....SENNFIASVSa....CSNG...
  46 KEKeskkiGPMARDIQRFVTPGTLLS....STLLq..E.....KFNNYIVAINr....IGSL...
  47 GGK.....GLVPRTINRLITPGALLS....SSLLp..E.....KANNYIIAISq....VGSL...
  48 KYS.....KENDWQLAFKASPGNLTQf...EEIL...F.....GNNDMSTAVGv....10se...
  49 KAK.....GIVKREVVRVITPGTFFE....----...-.....RDTGGLASLYk....KGNH...
  50 AKEmr...6skGIVKRELQCILTSGT....LTDG...D.....MLhSDLATFC.....LAIRe..
  51 AKEmr...6skGIVKRELQCILTSGT....LTDG...D.....MLhSDLATFC.....LAIRe..
  52 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMSASIGv....10vd...
  53 LKAig...6ksSVFSRKLTALYTKST....LIGE...D.....VNPl16tdTS.....TNYL...
  54 EAKkr...6ykAVVTRDVTRIITPGT....IIEE...N.....LIsVTEPNYL.....TSLVipk
  55 GKEi....11eeKVVQRGLTQVLTSG....TLVD...E.....AMLtSDLSTY.....CMAI...
  56 VPG.....ELTQRKVIEIISPGTAVE....DDFLs..Q.....GFSQYLATVCa....SDAT...
  57 QLEq....10kdKVVKREVCAVVTKG....TLTD...G.....EMLltNPDAS.....YLMA...
  58 EAKkrgskSVVRRDVVRLVTPGTITE....DKLLs..P.....SESNYLMALArirsgSEPA...
  59 TPD.....QLEq10kdKVVKREVCAV....VTKG...T.....LTDGEMLltN.....PDAS...
  60 LKAig...6rsSLFSRKLTALYTKST....LIGE...D.....VNPl16tdTS.....TSYL...
  61 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMSASIGv....10vd...
  62 ---.....---NWRLVKTGSPGNIGSf...EDVL...FannemQDTPVVVSIFpsfhdGRCV...
  63 LKAig...6rsSLFSRKLTALYTKST....LIGE...D.....VNPl16tdTS.....TSYL...
  64 TSG.....GPLEREVVEVITPGVIID....EDFLn..D.....DINNYLVAISd....YKDY...
  65 MLEe....10keKVVRREVCRVTSNG....TRTY...G.....VLDGv11ldP.....TAKH...
  66 QTK.....GMVRREVVRIVTPGTVMEq...GGVD...D.....KQNNYILSFVm....NQPE...
  67 -VK.....NSSDWEIEYRGSPGNLLQf...EDIL...F.....SNKEVLVGNSi....11gg...
  68 SPS.....GRMNWKVVKQASPGNLQDv...EDELggqF.....EGAPVILAVKis...6asE...
  69 -VK.....NSSDWEIEYRGSPGNLLQf...EDIL...F.....SNKEVLVGNSi....11gg...
  70 LKSts...6rnTLFDRRVARVLTKGT....TLDD...S.....FFr-fe9tlQ.....ASQF...
  71 LKSts...6rnTLFDRRVARVLTKGT....TLDD...S.....FFr-fe9tlQ.....ASQF...
  72 MMTe....12fdKVVAREICQITNRG....TQVF...G.....SQCkig-pnH.....QPNY...
  73 TSA.....IKKhd8ksSVFERKISNV....FTKA...T.....FGVNSTFVlr.....7ilG...
  74 IKShg...6rtGPFFRGLSALYTKAT....LEAa...E.....DISGgc9fgS.....QSNF...
  75 ---.....---NWRLVKTGSPGNIGSf...EDVL...FannemQDTPVVVSIFpsfhdGRCV...
  76 TSA.....IKKhd8ksSVFERKISNV....FTKA...T.....FGVNSTFVlr.....7ilG...
  77 ---.....------GWKLIKSASPGN....IEQv...N.....ELMnmnIDSS.....IIIA...
  78 ---.....------GWKLIKSASPGN....IEQv...N.....ELMnmnIDSS.....IIIA...
  79 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMSASIGv....10vd...
  80 SSK.....NMYIRSVTRVITPGTLID....ENFMn..P.....YESNYILTVVf....22cf...
  81 QAKarganTIIPRKLVQVLTPSTASE....GNIG...P.....-DAVHLLAIKei...8qkC...
  82 -VK.....NSSDWEIEYRGSPGNLLQf...EDIL...F.....SNKEVLVGNSi....11gg...
  83 ---.....---NWRLTKSGTPGNIGSf...EDIL...FanndmEDSPVIVALFpacreSQLY...
  84 QAKarganTIIPRKLVQVLTPSTASE....GNIG...P.....-DAVHLLAIKei...8qkC...
  85 ANS.....AKTGFELLKQASPGNMQMl...EDLL...Vs....13dsSVSSVL.....LAVTtrv
  86 ANS.....AKTGFELLKQASPGNMQMl...EDLL...Vs....13dsSVSSVL.....LAVTtrv
  87 IKShg...6rtGPFFRGLSALYTKAT....LEAa...E.....DISGgc9fgS.....QSNF...
  88 QAKargvhSVIERKLVHVSTPSTAVDni..----...G.....TDAVHLLALKev...7ssG...
  89 QAKargvhSVIERKLVHVSTPSTAVDni..----...G.....TDAVHLLALKev...7ssG...
  90 IKShg...6rtGPFFRGLSALYTKAT....LEAa...E.....DISGgc9fgS.....QSNF...
  91 VADnea..NKFYRRVTRIVTPGTFID....EAFEn..L.....RENTYLLNIEf....11ad...
  92 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMSASIGv....10vd...
  93 VADnea..NKFYRRVTRIVTPGTFID....EAFEn..L.....RENTYLLNIEf....11ad...
  94 ---.....-SSEQGEWKMTKRGSPGN....TVDfe..Q.....EIGVSDQAPI.....LAIYihp
  95 -PP.....GGGTYACVQRGSPGNITDf...EATL...Fs....22nkGGNAGK.....CMISg..
  96 KAS.....KENDWYLAYKASPGNLSQf...EDIL...F.....GNNDMSASIGv....10vd...
  97 ---.....--------PMAGPGGIEE....EDEE...E.....PAEIHLCVLW.....SSGY...
  98 ---.....--------PMAGPGGIEE....EDEE...E.....PAEIHLCVLW.....SSGY...
  99 ---.....------VTRVITPGTLID....ENFMn..P.....YESNYILTVVf....22cf...
 100 ---.....------------------....--EQ...F.....RDETVLSLSF.....AQGM...
 101 ---.....------------------....--EQ...F.....RDETVLSLSF.....AQGM...
 102 ---.....------------------....-AIS...A.....HSPSVIVAVV.....EGRGlar
 103 ---.....------------------....----...-eee..LAEIHLCVLW.....NSGY...
 104 ---.....------------------....-AIS...A.....HSPSVIVAVV.....EGRGlar
 105 ---.....------------------....----...-eee..LAEIHLCVLW.....NSGY...
 106 ---.....------------------....----...-eee..LAEIHLCVLW.....NSGY...
 107 ---.....------------------....--LLg..P.....SIDCVLCCIYevprdISTR...
 108 ---.....------------------....--LLg..P.....SIDCVLCCIYevprdISTR...
 109 ---.....------------------....--EQ...F.....RDETVLSLSF.....AQGM...
 110 -KS.....GPKQRAVSQVYSPSCNLE....DCPEl..-.....---PYVLSIYfs...QDDL...
 111 ---.....------------------....----...-.....NSDVVIVV--me...6gsC...
 112 ---.....------------------....----...-.....----------.....----...
 113 LKAig...6ksSVFSRKLTALYTKST....LIGE...D.....VNPl16tdTS.....TNYL...
 114 ---.....------------------....----...-.....----------.....----...
 115 IKShg...6raGPFFRGLSGLYTKAT....LEAa...E.....DISGgc9fgG.....QSNF...
 116 ---.....------------------....----...-fdf..DEEIVMCIDF.....SGGK...
 117 ---.....------------------....----...-st...8dfDEEIVMC.....ID-f...
 118 QAQg....PLVRREITRIITPGTILE....EGMLq..A.....RRNNFLAAVVi....AGEH...
 119 SSK.....NMYIRSVTRVITPGTLID....ENFMn..P.....YESNYILTVV.....----...


             150       160            170       180                    
              |         |              |         |                    
   1 ..WGLAFLDVSTGEFKGTVLKS.....KSALYDELFRHRPAEVLL.....APELLE.....N...
   2 ..WGLAFLDVSTGEFKGTVLKS.....KSALYDELFRHRPAEVLL.....APELLE.....N...
   3 ..FGYATLDISSGRFRLSEPAD.....RETMAAELQRTNPAELLY.....AEDFAE.....Ms..
   4 ..FGYATLDISSGRFRLSEPAD.....RETMAAELQRTNPAELLY.....AEDFAE.....Ms..
   5 ..FAYATLDISSGRFRLSEPAD.....RETMAAELQRTNPAELLY.....AEDFAE.....Ms..
   6 ..WGLAFLDVSTGEFKGTLLKS.....KSALYDELFRHRPAEVLL.....APELRE.....N...
   7 ..WGLAFLDVSTGEFKGTLLKS.....KSALYDELFRHRPAEVLL.....APELRE.....N...
   8 ..FGLATLDMTSGRFQLCEPAD.....KETLRAELQRIAPVELLY.....CEEFNE.....Ma..
   9 ..FGLAILDITSGRFNVQEIQG.....WENLLAELERLNPAELLY.....PDDWPA.....Gl..
  10 ..FGLAVLDITSGRFSVQEIKG.....WETLLAELERLNPAELLI.....PDDWPQ.....Gl..
  11 ..FGLAVLDITSGRFSVQEIKG.....WETLLAELERLNPAELLI.....PDDWPQ.....Gl..
  12 ..FGYATMDITSGRFQLSEPQT.....EEEMAAELQRTSPRELLF.....PEDFSP.....Vh..
  13 ..WGLAFLDVSTGEFKGTLLKS.....KSALYDELFRHRPAEVLL.....APELRE.....N...
  14 ..YGYATLDISSGRFRLSEPAD.....RETMAAELQRTNPAELLY.....AEDFAE.....Ma..
  15 ..WGLAFLDVSTGEFKATLLKS.....KSALYDELFRHRPAEVLL.....APELRE.....N...
  16 ..YCTVFCDVSTGEVLVHESSD.....EQETLDLLKNYSISQIIC.....PEHLKS.....S...
  17 ..GQRQVGVGYVDSIQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECV.....L...
  18 ..GQRQVGVGYVDSIQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECV.....L...
  19 ..GQRQVGVGYVDSIQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECV.....L...
  20 ..YCTVFCDVSTGEVLVHESSD.....EQETLDLLKNYSISQIIC.....PEHLKS.....S...
  21 ..WGLAHADISTGEFFTCQSSN.....LDDLAVELLRLQPSEVLI.....PTSAPD.....I...
  22 ..WGLAHADISTGEFFTCQSSN.....LDDLAVELLRLQPSEVLI.....PTSAPD.....I...
  23 ..GQRHVGVGYVDSTQRKLGLC.....EFPEndqFSNLEALLIQI.....GPKECV.....L...
  24 ..GQRHVGVGYVDSTQRKLGLC.....EFPEndqFSNLEALLIQI.....GPKECV.....L...
  25 ..Kek8sgHTRAYGVCFVDTSL.....GKFFIGQFSDdrhCSRFR.....TLVAHY.....P...
  26 ..Kek8sgHTRAYGVCFVDTSL.....GKFFIGQFSDdrhCSRFR.....TLVAHY.....P...
  27 ..Kek8sgHTRAYGVCFVDTSL.....GKFFIGQFSDdrhCSRFR.....TLVAHY.....P...
  28 ..Kek8sgHTRAYGVCFVDTSL.....GKFFIGQFSDdrhCSRFR.....TLVAHY.....P...
  29 ..YGYATLDISSGRFRLSEPAD.....RETMAAELQRTNPAELLY.....AEDFAE.....Ma..
  30 ..Kek8sgHTRVYGVCFVDTSL.....GKFFIGQFSDdrhCSRFR.....TLVAHY.....P...
  31 ..GQRQVGVGDVDSTQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECI.....L...
  32 ..Kek8sgHTRAYGVCFVDTSL.....GKFFIGQFSDdrhCSRFR.....TLVAHY.....P...
  33 ..Kek8sgHTRVYGVCFVDTSL.....GKFFIGQFSDdrhCSRFR.....TLVAHY.....P...
  34 ..FGLAYMDLVTGDFYVTGLLD.....FTLVCGEIRNLKAREVVL.....GYDLSE.....Eeeq
  35 ..YGLSCLDLSIGTFLVAEYDN.....TKDLIEAICRLAPTELLS.....HAKFYQ.....Kn..
  36 ..IGLAWASLQSGEFKTKLTT-.....VDKLDDELARLQAAEILL.....PDSKNA.....P...
  37 ..YGLALSDLTTGENLAVLIER.....LEDVISEIYSVGAREIVV.....SGSLDA.....D...
  38 ..IGLAWASLQSGEFKTKLTT-.....VDKLDDELARLQAAEILL.....PDSKNA.....P...
  39 ..YGLAWADLAGGRFLVNEVNS.....EEALEAELARLEPAELLLp....DEDAWP.....E...
  40 ..FGFACLDLSTGSFFIEECEN.....TKELVDEICRLAPSEVLS.....CNKFYN.....Ke..
  41 ..LCIYe11kkGNLSVGVVGVQ.....PATGEVVFDCFQDsasRL.....ELETRI.....S...
  42 ..LCIYe11kkGNLSVGVVGVQ.....PATGEVVFDCFQDsasRL.....ELETRI.....S...
  43 ..LCIYe11kkGNLSVGVVGVQ.....PATGEVVFDCFQDsasRL.....ELETRI.....S...
  44 ..YLVSYLNLSVGEFIGAKVK-.....EEELIDFLSKFNIREVLVkk...GEKLPE.....K...
  45 ..YGLALSDLTTGENLAVLIER.....LEDVISEIYSVGAREIVV.....SGSLDA.....D...
  46 ..FGFACLDLSTGSFFIEECEN.....TKELVDEICRLAPSEVLS.....CNKFYN.....Ke..
  47 ..YGLSCLDLSTGTFLVAEYDN.....TKDLIEAVYRLAPTELLS.....HAKFYQ.....Kn..
  48 ..GQRLVGVGYVDSTLRKLGVC.....EFPDndqFSNLEALLVQI.....GPKECV.....M...
  49 ..YYVGYLNLAVGEFLGAKVK-.....IEELLDLLSKLNIKEILVkk...GEKLPE.....E...
  50 ..21klNTKIFGAAFIDTATGE.....LQMLEFEDdseCTKLDTL.....MSQVRP.....M...
  51 ..21klNTKIFGAAFIDTATGE.....LQMLEFEDdseCTKLDTL.....MSQVRP.....M...
  52 ..GQRQVGVGYVDSIQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECV.....L...
  53 ..LCIYe11kkGNLSVGVVGVQ.....PATGEVVFDCFQDsasRL.....ELETRI.....S...
  54 ..NKKTASICCVDLSTSKIFVI.....NVP-ETEILNELARLKSR.....EILLSE.....N...
  55 ..Kes7dnEEPSFGICFIDTST.....GGFHMCEFTDdihRTKLD.....TLLTQV.....R...
  56 ..VAFSYLEVSTGAFFITSFPRaea..ADALQKEFGRVQPSEVLL.....SASVLR.....S...
  57 ..LTeg6sl----tn8hnFGVC.....LVDVATQKIILGQFKDdqd....CSALSC.....L...
  58 ..YALAWIDISTGIFRLAETA-.....ESRLLADILRIEPRELIL.....PDTVFH.....D...
  59 ..YLMALTeg6sl----tn8hn.....FGVCLVDVATQKIILGQF.....KDdqdC.....S...
  60 ..LCISe11kk----gnifIGI.....VGVQPATGEVVFDSFQDsas...RSELET.....R...
  61 ..GQRQVGVGYVDSIQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECV.....L...
  62 ..IGMAYVDLTRRVLGLAEFLDdsr..FTNLESSLIALGAKECIFpa...ESGKSN.....E...
  63 ..LCISe11kk----gnifIGI.....VGVQPATGEVVFDSFQDsas...RSELET.....R...
  64 ..YSFSYIDLSTSSLGIMFYENgf...FEKLKRDLEKYSPKEIIV.....SENFYY.....Eyse
  65 ..LLAIKef7etGKSSYGVCMI.....DTTTAHIRIGQFEDddyR.....SQLRTL.....L...
  66 ..IALSYCDVSTGELKVTHFND.....EATLLNEITTINPNEVVI.....NDNISD.....N...
  67 ..GQRRVGVASVEQNDCKFQLL.....EFLDddfFTELEATVVLL.....GPKECL.....L...
  68 ..ARTVGVCFADASVRELGVSE.....FLDndlYSNFEALLIQLG.....VKECIVtqdkgE...
  69 ..GQRRVGVASVEQNDCKFQLL.....EFLDddfFTELEATVVLL.....GPKECL.....L...
  70 ..ILCVAdn9akSGR-vqVGLI.....AIQLSSGTTVYDHFQDdfl....RSELQT.....R...
  71 ..ILCVAdn9akSGR-vqVGLI.....AIQLSSGTTVYDHFQDdfl....RSELQT.....R...
  72 ..MLAIVekdegTCSRYGVCFI.....DTSIGDFHLGEFEDdknC.....SRLLTL.....V...
  73 ..DTNSIWALSrdvhQGK-vak.....YSLISVNLNNGEVVYDEF.....EEpnla.....D...
  74 ..LVCVVDERVk16vrVGVVGV.....EISTGEVVYEEFNDnfmR.....SGLEAV.....I...
  75 ..IGMAYVDLTRRVLGLAEFLDdsr..FTNLESSLIALGAKECIFpa...ESGKSN.....E...
  76 ..DTNSIWALSrdvhQGK-vak.....YSLISVNLNNGEVVYDEF.....EEpnla.....D...
  77 ..SLKvq7qdGNCIIGVAFIDT.....TAYKVGMLDIVDnevYSN.....LESFLI.....Q...
  78 ..SLKvq7qdGNCIIGVAFIDT.....TAYKVGMLDIVDnevYSN.....LESFLI.....Q...
  79 ..GQRQVGVGYVDSIQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECV.....L...
  80 ..ADCKIGLSWLDLSTGEFFTQ.....DSN-LQRLAGDLTRISPR.....EIVLDE.....S...
  81 ..STVYGFAFVDCAALRFWVGS.....ISDdasCAALGALLMQVS.....PKEVLYd....S...
  82 ..GQRRVGVASVEQNDCKFQLL.....EFLDddfFTELEATVVLL.....GPKECL.....L...
  83 ..VGLSFLDMTNRKLGLAEFPEdsr..FTNVESALVALGCKECLL.....PADCEK.....Sid.
  84 ..STVYGFAFVDCAALRFWVGS.....ISDdasCAALGALLMQVS.....PKEVLYd....S...
  85 kqDQRIIGVAFIDPILKKLGVS.....EFVDsdaYTNFEALIVQV.....GAKECI.....I...
  86 kqDQRIIGVAFIDPILKKLGVS.....EFVDsdaYTNFEALIVQV.....GAKECI.....I...
  87 ..LVCVVDERVk16vrVGVVGV.....EISTGEVVYEEFNDnfmR.....SGLEAV.....I...
  88 ..FQVFGFAFLDYAALKIWVGS.....VQDddsSAALGALLMQVS.....PRELIY.....E...
  89 ..FQVFGFAFLDYAALKIWVGS.....VQDddsSAALGALLMQVS.....PRELIY.....E...
  90 ..LVCVVDERVk16vrVGVVGV.....EISTGEVVYEEFNDnfmR.....SGLEAV.....I...
  91 ..TSLKVGICWCDVSTGEIFVQ.....QVY-LRDLVSAITRIQPK.....EILLDE.....R...
  92 ..GQRQVGVGYVDSIQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECV.....L...
  93 ..TSLKVGICWCDVSTGEIFVQ.....QVY-LRDLVSAITRIQPK.....EILLDE.....R...
  94 gdDDNRVTLCAWDAGNVRIVIS.....EYIDtpsFSQTEQCIFGL.....CPTEYI.....Lvn.
  95 ..-GQGirVGFAALNTTLRTLT.....YAEYLDtlqLTSLDALMA.....QCNLKE.....L...
  96 ..GQRQVGVGYVDSIQRKLGLC.....EFPDndqFSNLEALLIQI.....GPKECV.....L...
  97 ..LGIAYYDTSDSTIHFMPDAPdhes.LKLLQRVLDEINPQSVVT.....SAKQDE.....A...
  98 ..LGIAYYDTSDSTIHFMPDAPdhes.LKLLQRVLDEINPQSVVT.....SAKQDE.....A...
  99 ..ADCKIGLSWLDLSTGEFFTQ.....DSN-LQRLAGDLTRISPR.....EIVLDE.....S...
 100 ..LGAAYYEQSSQLLKIMNDISedle.FRFLKRLIDDVKPTLIIA.....NRSQDL.....E...
 101 ..LGAAYYEQSSQLLKIMNDISedle.FRFLKRLIDDVKPTLIIA.....NRSQDL.....E...
 102 geIGMASIDLKNPQIILSQFADntt..YAKVITKLKILSPLEIIM.....SNTACA.....V...
 103 ..LGIAYYDTSDSTIHFMPDAPdhes.LKLLQRVLDEINPQSVVT.....SAKQDE.....N...
 104 geIGMASIDLKNPQIILSQFADntt..YAKVITKLKILSPLEIIM.....SNTACA.....V...
 105 ..LGIAYYDTSDSTIHFMPDAPdhes.LKLLQRVLDEINPQSVVT.....SAKQDE.....N...
 106 ..LGIAYYDTSDSTIHFMPDAPdhes.LKLLQRVLDEINPQSVVT.....SAKQDE.....N...
 107 ..IGLCIINCNTGQMYLSDFMDsqi..YIRVVHKLQIYQPTEILI.....PSSSLA.....P...
 108 ..IGLCIINCNTGQMYLSDFMDsqi..YIRVVHKLQIYQPTEILI.....PSSSLA.....P...
 109 ..LGAAYYEQSSQLLKIMNDISedle.FRFLKRLIDDVKPTLIIA.....NRSQDL.....E...
 110 ..LGITLFSAMNGHSIIFPVSWtd...RDKVTRLLISYHIREIVIwa...DSGVCS.....Nil.
 111 ..EGHIGIALHDTCFPEIHLCE.....FVDsreYTTLKTMINVHE.....AFDIVI.....Q...
 112 ..--------------------.....------------------.....------.....-...
 113 ..LCIYe11kkGNLSVGVVGVQ.....PATGEVVFDCFQDsasRL.....ELETRI.....S...
 114 ..--------------------.....------------------.....------.....-...
 115 ..LVCVVDERVd17vrVGVVGV.....EISTGEVVHGEFNDnfmR.....SGLEAV.....I...
 116 ..LGCSILDYHTKTLKAFDQDYv....23diSLLLGLLIMEANPT.....VCLVPA.....R...
 117 ..SGGKLGCSILDYHTKTLKAF.....DQDYvvnk--------TT.....ISSHDL.....I...
 118 ..WGLAYADSSTGDYWTSQSTG.....LEGL--------------.....------.....-...
 119 ..--------------------.....------------------.....------.....-...


       190       200            210       220       230               2
        |         |              |         |         |                
   1 .GAFLDEFRKRFPVMLSEA.....PFEPEGEGPLALRRARGALLAYAQRTQGG.....AL...SL
   2 .GAFLDEFRKRFPVMLSEA.....PFEPEGEGPLALRRARGALLAYAQRTQGG.....AL...SL
   3 .LIEGRRGLRRRPLWEFEId....15rdLVGFGVENAPRGLCAAGCLLQYAKD.....TQ...RT
   4 .LIEGRRGLRRRPLWEFEId....15rdLVGFGVENAPRGLCAAGCLLQYAKD.....TQ...RT
   5 .LIEGRRGLRRRPLWEFEId....15rdLVGFGVENAPRGLCAAGCLLQYAKD.....TQ...RT
   6 .EAFVAEFRKRFPVMLSEA.....PFEPQGEGPLALRRAQGALLAYARATQGG.....AL...SV
   7 .EAFVAEFRKRFPVMLSEA.....PFEPQGEGPLALRRAQGALLAYARATQGG.....AL...SV
   8 .AIEHCKGLRRRPIWEFELs....15kdLRAFGVEKSPLGLSAAGCLLQYAKE.....TQ...RT
   9 .PLEKRRGAHRRAPWDFDFd....15qdLKGFGCDGLGLAIGAAGCLLAYARE.....TQ...RT
  10 .PAEKRRGVRRRAPWDFDRd....15qdLKGFGCQNLTLAIGAAGCLLAYAKE.....TQ...RT
  11 .PAEKRRGVRRRAPWDFDRd....15qdLKGFGCQNLTLAIGAAGCLLAYAKE.....TQ...RT
  12 .LMASRQGNRRRPIWEFELd....15rdLVGFGVEQAKLGLCAAGCLIQYVKD.....TQ...RT
  13 .EAFVAEFRKRFPVMLSEA.....PFEPQGEGPLALRRAQGALLAYARATQGG.....AL...SV
  14 .LIEGRRGLRRRPLWEFEId....15rdLVGFGVENASRGLCAAGCLLQYVKD.....TQ...RT
  15 .EAFVAQFRKRFPVMLSEA.....PFDPEGEAPLALSRARGALLAYARATQGG.....AL...SV
  16 .LKERFPGVYTETISEWYFs....12nlKDIHHFELSPLALKALAALIKYVKY.....TM...IG
  17 .PGGETAGdMGKLRQIIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  18 .PGGETAGdMGKLRQIIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  19 .PGGETAGdMGKLRQIIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  20 .LKERFPGVYTETISEWYFs....12nlKDIHHFELSPLALKALAALIKYVKY.....TM...IA
  21 .RNILRPGEPSEHIPKQLPt....30ksLEGMGCEGLPLAIRAAGGLLEYIED.....TQ...KA
  22 .RNILRPGEPSEHIPKQLPt....30ksLEGMGCEGLPLAIRAAGGLLEYIED.....TQ...KA
  23 .PGGETTGdMGKLRQVIQR.....GGILITERk27inSAALPEMENQVAVSSL.....SA...VI
  24 .PGGETTGdMGKLRQVIQR.....GGILITERk27inSAALPEMENQVAVSSL.....SA...VI
  25 .PVQVLFEKGNLSKeTKTI.....LKSSLSCSLQEGLIp46dsIGLTPGEKSE.....LA...LS
  26 .PVQVLFEKGNLSKeTKTI.....LKSSLSCSLQEGLIp46dsIGLTPGEKSE.....LA...LS
  27 .PVQVLFEKGNLSKeTKTI.....LKSSLSCSLQEGLIp46dsIGLTPGEKSE.....LA...LS
  28 .PVQVLFEKGNLSKeTKTI.....LKSSLSCSLQEGLIp46dsIGLTPGEKSE.....LA...LS
  29 .LIEGRRGLRRRPLWEFEId....15rdLVGFGVENASRGLCAAGCLLQYVKD.....TQ...RT
  30 .PVQILFEKGNLSTeTKTV.....LKGSLSSCLQEGLIp44dsVGLTPGEESE.....LA...LS
  31 .PGGETAGdMGKLRQVIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  32 .PVQVLFEKGNLSKeTKTI.....LKSSLSCSLQEGLIp46dsIGLTPGEKSE.....LA...LS
  33 .PVQILFEKGNLSTeTKTV.....LKGSLSSCLQEGLIp44dsVGLTPGEESE.....LA...LS
  34 iLSRQMNLVLSYEKESFED.....LHLLDLRLATVEQTASSKLLQYVHRTQMR.....ELn..HL
  35 .EAVIKQLQQHLRITLSEYv....22ssLDGFGLQGLVPAINAAGALLSYIQD.....KL...LL
  36 .QLQTASGVTRLNAWQFAAd....17lrGFGLDGKEHAVAIGAAGALLNYIRL.....TQ...NL
  37 .TVAQLRERCGATISIEDGetdehVTIIEHLNNEDITKTFLRLYTYLKRTQKR.....SLd..HL
  38 .QLQTASGVTRLNAWQFAAd....17lrGFGLDGKEHAVAIGAAGALLNYIRL.....TQ...NL
  39 .YLQQRNGVRRRPPWLFDAd....15hdLSGFGIENNPQATAAAGALLGYIEE.....TQ...KQ
  40 .TAIVMQLQQHLKLTLSTYa....22asLDGFGLKGLVPAINAAGGLLSYIQD.....KL...LL
  41 .SLQPVELLLPSDLSEPTE.....MLIQRATNVSVRDDRIr34sqSLSGVINL.....EK...PV
  42 .SLQPVELLLPSDLSEPTE.....MLIQRATNVSVRDDRIr34sqSLSGVINL.....EK...PV
  43 .SLQPVELLLPSDLSEPTE.....MLIQRATNVRLKTVRKl55sqSLSGVINL.....EK...PV
  44 .LEKVLKLHITELEEEFFEe....13vpSIKAFGFQDEDLSLSLGAVYRYAKA.....TQ...KS
  45 .TVAQLRERCGATISIEDGetdehVTIIEHLNNEDITKTFLRLYTYLKRTQKR.....SLd..HL
  46 .TAIVMQLQQHLKLTLSTYa....22asLDGFGLKGLVPAINAAGGLLSYIQD.....KL...LL
  47 .EPVVKQLQQHLRITLSEHv....22ssLDGFGLQGLVPAINAAGALLSYIQD.....KL...LL
  48 .PGGETAGdMGKLRQIVKR.....GGILITDRk27vtSAALPEMEKQVAMSAL.....AA...VM
  49 .LEKVLKVYVSELEEEFFEe....13vlSLQAFGFEEDTYSLPLGAVYKYAKT.....TQ...KG
  50 .EVVMERNNLSTLANKIVK.....FNSAPNAIFNEv32evLKSYYDTGKKVGF.....SA...FG
  51 .EVVMERNNLSTLANKIVK.....FNSAPNAIFNEv32evLKSYYDTGKKVGF.....SA...FG
  52 .PGGETAGdMGKLRQIIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  53 .SLQPVELLLPSDLSEPTE.....MLIQRATNVSVRDDRIr34sqSLSGVINL.....EK...PV
  54 .LKSSnISDSILKQFNCRI.....TYQVDs19irDIKGIGEISNSQICAIGSI.....LE...YL
  55 .PKELILEKSKISQksIRA.....IKYCVSSSSIWNFIKp30pkILKSYLSEK.....PL...AI
  56 .LPELAAILSLYPRLVRTTg....23rnLDCLTLLPHSPDLAAAGALIAYLEE.....TT...RH
  57 .LSEMRPVEIIKPAKVLSYa....TERTIVRQTRNPLVNNLVp49lsELATED.....KN...GS
  58 .PDLRPVFDVLGRVAVPQPa....20vgTLDGFGSFSRAELAAASAAVSYVEK.....TQ...LQ
  59 .ALSCLLSEMRPVEIIKPA.....KVLSYaTERTIVRQTRNPLVNNLVp49ls.....EL...AT
  60 .MSSLQPVELLLPSALSEQ.....TEALIHRATSVSVQDDRIr34sqIISGIV.....NL...EK
  61 .PGGETAGdMGKLRQIIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  62 .CKSLYDSLERCAVMITERk....23iePVRDLVSGFDLATPALGALLSFSEL.....LS...NE
  63 .MSSLQPVELLLPSALSEQ.....TEALIHRATSVSVQDDRIr34sqIISGIV.....NL...EK
  64 kLNLSRFLINRVPTWHLDKd....15lgLSSLGFDEEKPYYISIFLIINHIKN.....NL...KN
  65 .ANVIVVQAIVERGSISST.....TKSIINGILFSVPVEHLl41ssILPKPST.....DW...QL
  66 .LKRQINMVTETITVRETLsse..IYSVNQTEHKLMYQATQLLLDYIHHTQKR.....DLs..HI
  67 .P-SIEGEYSAVKTLLDRN.....GVMITMPk25edATGLKELQLQLASNALK.....TA...IK
  68 .KEKDPELAKLRQIIDNCG.....VAIAERs23raASLLPQTDLKLAMGSASA.....LI...KY
  69 .P-SIEGEYSAVKTLLDRN.....GVMITMPk25edATGLKELQLQLASNALK.....TA...IK
  70 .LSHFQPCELIYSNKLSSE.....SVALLNHYVSTEKTCGRVv36elHMEKVK.....SL...HS
  71 .LSHFQPCELIYSNKLSSE.....SVALLNHYVSTEKTCGRVv36elHMEKVK.....SL...HS
  72 .SHHMPVLFLNEKSALSQR.....TQQIVRTVLGGILKEPVp44dhLGLTPND.....NY...KL
  73 .EKLQIRIKYLQPIEVLVN.....TDDLPLHVAKFFKDISCPLIHKQEy12ik.....VM...NE
  74 .LSLSPAELLLGQPLSQQT.....EKFLVAHAGPTSNVRVEr46clTVHTIMN.....MP...HL
  75 .CKSLYDSLERCAVMITERk....23iePVRDLVSGFDLATPALGALLSFSEL.....LS...NE
  76 .EKLQIRIKYLQPIEVLVN.....TDDLPLHVAKFFKDISCPLIHKQEy12ik.....VM...NE
  77 .LGVKECLVqdltsNSNSN.....AEMQKVINVIDRCGCVVTLLk22dlALSL.....PQ...KY
  78 .LGVKECLVqdltsNSNSN.....AEMQKVINVIDRCGCVVTLLk22dlALSL.....PQ...KY
  79 .PGGETAGdMGKLRQIIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  80 .LKSFtTHPIYSFIQERKY.....FLSYVe18eiDPSFIKYCTKLEVTAGCTL.....IS...YI
  81 .KGLSREAQKALRKYTLTG.....STAVQLa33wnCAVDGLNECDVALSALGE.....LI...NH
  82 .P-SIEGEYSAVKTLLDRN.....GVMITMPk25edATGLKELQLQLASNALK.....TA...IK
  83 .LNPLQDVISNCNVLLTEKk....23vePVRDLLSQFDYALGPLGALLSYAEL.....LA...DD
  84 .KGLSREAQKALRKYTLTG.....STAVQLa33wnCAVDGLNECDVALSALGE.....LI...NH
  85 .SQSGHEs13taEINRLRN.....IIEGCGALVTTIr23vtHALVPELGLQLA.....MA...SC
  86 .SQSGHEs13taEINRLRN.....IIEGCGALVTTIr23vtHALVPELGLQLA.....MA...SC
  87 .LSLSPAELLLGQPLSQQT.....EKFLVAHAGPTSNVRVEr46clTVQTIMN.....MP...HL
  88 .TSGISKeTQRTIRKYASA.....GSVKMQLt32wlSALDCTMNQDVVICALG.....GL...IG
  89 .TSGISKeTQRTIRKYASA.....GSVKMQLt32wlSALDCTMNQDVVICALG.....GL...IG
  90 .LSLSPAELLLGQPLSQQT.....EKFLVAHAGPTSNVRVEr46clTVHTIMN.....MP...HL
  91 .LLEf10ypELVELKKFFI.....KYQKMPSQHr21rqLKIQFQTFTQKELAA.....LR...NT
  92 .PGGETAGdMGKLRQIIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  93 .LLEf10ypELVELKKFFI.....KYQKMPSQHr21rqLKIQFQTFTQKELAA.....LR...NT
  94 .EGSVAPKAKKIASMFTRM.....EVHNKQQl13esVHLDYKDEAEKQNENIK.....EC...LQ
  95 .IYlDKSRCRGGSNSDRGG.....GAAGVCRRKRa66vpEDRLALSNCPLASR.....AI...EY
  96 .PGGETAGdMGKLRQIIQR.....GGILITERk27mnSAVLPEMENQVAVSSL.....SA...VI
  97 .MTRFLGKLASEEHREPKGp....40lfLSSIIPFDCVLTVRALGGLLKFLSR.....RR...IG
  98 .MTRFLGKLASEEHREPKGp....40lfLSSIIPFDCVLTVRALGGLLKFLSR.....RR...IG
  99 .LKSFtTHPIYSFIQERKY.....FLSYVe18eiDPSFIKYCTKLEVTAGCTL.....IS...YI
 100 .FIKFLTTRYDPQEKIYEDg....84iiIKMRFDIEAVNMIRSFGALLLFLDE.....TR...MG
 101 .FIKFLTTRYDPQEKIYEDg....84iiIKMRFDIEAVNMIRSFGALLLFLDE.....TR...MG
 102 .GNSTKLFTLITENFKNVNf....27fsTVLMEVQSKYYCLAAVAALLKYVEF.....IQ...NS
 103 .MTRFLGKLASQEHREPKRp....40lfLSSIIPFDCLLTVRALGGLLKFLGR.....RR...IG
 104 .GNSTKLFTLITENFKNVNf....27fsTVLMEVQSKYYCLAAVAALLKYVEF.....IQ...NS
 105 .MTRFLGKLASQEHREPKRp....40lfLSSIIPFDCLLTVRALGGLLKFLGR.....RR...IG
 106 .MTRFLGKLASQEHREPKRp....57dlRFTPIPLLIPSQVRALGGLLKFLGR.....RR...IG
 107 .TVSKLATMIKFNVAETVKi....29kdLKIEEIIDKTFALCAASAAISYMEE.....II...SK
 108 .TVSKLATMIKFNVAETVKi....29kdLKIEEIIDKTFALCAASAAISYMEE.....II...SK
 109 .FIKFLTTRYDPQEKIYEDg....84iiIKMRFDIEAVNMIRSFGALLLFLDE.....TR...MG
 110 .INKIYNLLIGWNLFPSEPn....56ifQSTWTENVNQANLISLLGVLQFIKD.....RN...PN
 111 .NGNEERGSTKLLGEALMT.....AFPEASl27vsTVSEGCLRRTLALGALAV.....LL...KY
 112 .------------------.....-----------------------------.....--...--
 113 .SLQPVELLLPSDLSEPTE.....MLIQRATNVRLKT----------------.....--...--
 114 .------------------.....-----------------------------.....--...--
 115 .L-----------------.....-----------------------------.....--...--
 116 .LEDWi-------------.....-----f77dsTASSNMVTGRLVQNAFE--.....--...--
 117 .DDADMSSNDISLLLGLLI.....MEANPTVCl87dsTASSNMVTGRLVQNAF.....E-...--
 118 .------------------.....-----------------------------.....--...--
 119 .------------------.....-----------------------------.....--...--


      40             250       260            270       280        290 
      |               |         |              |         |          | 
   1 QPFRFYDP.....G.AFMRLPEATLRALEVFEPLRGQ.....DTLFSVLDETRT.APGRRLLQSW
   2 QPFRFYDP.....G.AFMRLPEATLRALEVFEPLRGQ.....DTLFSVLDETRT.APGRRLLQSW
   3 TLpHIRSI.....T.MEREQDSIIMDAATRRNLEITQ.....NLAGGaeNTLAS.VLDCTVTPMG
   4 TLpHIRSI.....T.MEREQDSIIMDAATRRNLEITQ.....NLAGGaeNTLAS.VLDCTVTPMG
   5 TLpHIRSI.....T.MEREQDSIIMDAATRRNLEITQ.....NLAGGaeNTLAS.VLDCTVTPMG
   6 RPFRLYDP.....G.AFVRLPEASLKALEVFEPLRGQ.....DTLFGVLDETRT.APGRRLLQAW
   7 RPFRLYDP.....G.AFVRLPEASLKALEVFEPLRGQ.....DTLFGVLDETRT.APGRRLLQAW
   8 ALpHIQSI.....S.LIQNQDCIQLDAATRRNLELTQ.....NLAGGteNTLAS.VLDKCVTPMG
   9 ALpHLRGL.....R.HERLDDTVILAGASRRNLELDV.....NLSGGrdNTLQS.VIDRCQTAMG
  10 ALpHLRSL.....R.HDRLDDTVILDGASRRNLELDI.....NLSGGreNTLQS.VVDRCQTAMA
  11 ALpHLRSL.....R.HDRLDDTVILDGASRRNLELDI.....NLSGGreNTLQS.VVDRCQTAMA
  12 ALpHIRSL.....T.WDRQDQSVILDAATRRNLELTH.....NLAGGtdNTLAE.VLDHCATPMG
  13 RPFRLYDP.....G.AFVRLPEASLKALEVFEPLRGQ.....DTLFGVLDETRT.APGRRLLQAW
  14 SLpHIRSI.....T.MERQQDSIIMDAATRRNLEITQ.....NLAGGveNTLAA.VLDCTVTPMG
  15 RPFRLYDP.....G.AIVRLPEASLKALEVFEPLRGQ.....DTLFGVLDETRT.APGRRLLQAW
  16 EDlNLKPP.....L.LISQRDYMILDSATVENLSWIP.....GDRGKn--LFDV.LNNTETPMGA
  17 KFLELLSD.....D.SNfGQFELTTFDFSQYMKLDIA.....AVRALNLFQGSV.EDttgsQSLA
  18 KFLELLSD.....D.SNfGQFELTTFDFSQYMKLDIA.....AVRALNLFQGSV.EDttgsQSLA
  19 KFLELLSD.....D.SNfGQFELTTFDFSQYMKLDIA.....AVRALNLFQGSV.EDttgsQSLA
  20 EDlNLKPP.....L.LISQRDYMILDSATVENLSLIP.....GDRGKn--LFDV.LNNTETPMGA
  21 HVvPIQPL.....K.TYGLTDFLVLDHQTRRNLEINQ.....TVRDGsfhGSLL.WALDRTSTTM
  22 HVvPIQPL.....K.TYGLTDFLVLDHQTRRNLEINQ.....TVRDGsfhGSLL.WALDRTSTTM
  23 KFLELLSD.....D.SNfGQFELATFDFSQYMKLDMA.....AVRALNLFQGSV.EDttgsQSLA
  24 KFLELLSD.....D.SNfGQFELATFDFSQYMKLDMA.....AVRALNLFQGSV.EDttgsQSLA
  25 ALGGCVFY.....L.KKCLIDQEllSMANFEEYIPl1.....8kaYQRMVLDAV.TLNNLEIFLN
  26 ALGGCVFY.....L.KKCLIDQEllSMANFEEYIPl1.....8kaYQRMVLDAV.TLNNLEIFLN
  27 ALGGCVFY.....L.KKCLIDQEllSMANFEEYIPl1.....8kaYQRMVLDAV.TLNNLEIFLN
  28 ALGGCVFY.....L.KKCLIDQEllSMANFEEYIPl1.....8kaYQRMVLDAV.TLNNLEIFLN
  29 SLpHIRSI.....T.MERQQDSIIMDAATRRNLEITQ.....NLAGGveNTLAA.VLDCTVTPMG
  30 ALGGIVFY.....L.KKCLIDQEllSMANFEEYFPl1.....8kaSQRMVLDAV.TLNNLEIFLN
  31 KFLELLSD.....D.SNfGQFELATFDFSQYMKLDMA.....AVRALNLFQGSV.EDttgsQSLA
  32 ALGGCVFY.....L.KKCLIDQEllSMANFEEYIPl1.....8kaYQRMVLDAV.TLNNLEIFLN
  33 ALGGIVFY.....L.KKCLIDQEllSMANFEEYFPl1.....8kaSQRMVLDAV.TLNNLEIFLN
  34 KPVIRYEI.....K.DFLQMDYATKASLDLVENARSGkkq..GSLFWLLDETKT.AMGMRLLRSW
  35 PIsHLSIP.....K.IYGQQKHLLIDKASQTNLELLS.....PIHGEhgkGSLL.QVMERTSTPM
  36 MPqHLDGL.....S.LETDSQYIGMDAATRRNLEITQ.....TLSGKksPTLMS.TLDLCATHMG
  37 QPVQVYEL.....E.EAMKIDLYSKRNLELTETIRSKnkk..GSLLWLLDETKT.AMGGRLLKQW
  38 MPqHLDGL.....S.LETDSQYIGMDAATRRNLEITQ.....TLSGKksPTLMS.TLDLCATHMG
  39 RLpHLTSI.....T.METVGEAITMNAATRRHLELDT.....RVDGEsrHTLLG.VLDSTVTPMG
  40 PTkHIAIP.....Q.TRGKQQKLLIDTASQVNLELLA.....PLNDPqgkNSLL.RIMDHTSTPM
  41 ICALAAVI.....R.YLKEFNLEKMlsKPESFKQLSS.....GmEFMRINGTTL.RNLEILQNQT
  42 ICALAAVI.....R.YLKEFNLEKMlsKPESFKQLSS.....GmEFMRINGTTL.RNLEMVQNQT
  43 ICALAAVI.....R.YLKEFNLEKMlsKPESFKQLSS.....GmEFMRINGTTL.RNLEILQNQT
  44 FTpLIPKP.....K.PYVDEGYVKLDLKAVKGLEITE.....SIEGRkdLSLFK.VVDRTLTGMG
  45 QPVQVYEL.....E.EAMKIDLYSKRNLELTETIRSKnkk..GSLLWLLDETKT.AMGGRLLKQW
  46 PTkHIAIP.....Q.TRGKQQKLLIDTASQVNLELLA.....PLNDPqgkNSLL.RIMDHTSTPM
  47 PIsHLSIP.....K.IYGQHKHLLIDKASQTNLELLS.....AIHGEhgkGSLL.QVMERTSTPM
  48 KYLELLSD.....E.SNfGQFVMTNFDLSQYMKLDNA.....AVGALNLFPGSA.EDtsgtQSLA
  49 YTpLIPRP.....K.PYRDEGFVRLDIKAIKGLEILE.....SLEGRkdISLFK.VIDRTLTGMG
  50 GLLYYLKW.....L.KLDKNliSMKNIKEYDFvksQH.....SMVLDGITLQNL.EIFSNSFDGs
  51 GLLYYLKW.....L.KLDKNliSMKNIKEYDFvksQH.....SMVLDGITLQNL.EIFSNSFDGs
  52 KFLELLSD.....D.SNfGQFELTTFDFSQYMKLDIA.....AVRALNLFQGSV.EDttgsQSLA
  53 ICALAAVI.....R.YLKEFNLEKMlsKPESFKQLSS.....GmEFMRINGTTL.RNLEMVQNQT
  54 SLTQKQNIp....H.LPIPKIINFHNYMTIDFSTRRN.....LEIVTNLQGNly.GSVLNTLNHT
  55 SAFGALFW.....Y.LRQLKLDKDmcSMGNFDEYDAsqq...STSLLMNGQTLK.NLEIFSNSFD
  56 PLsHVSAI.....T.RYHIHDFVEIDDATRKNLEILQ.....NLHDSthaHSLF.ETLNYTHTAM
  57 LALSALGG.....A.IYYLRQAFLDe10feSLPYCDF.....SNVNEKQHMVLD.AAALENLEIF
  58 ERpALGIP.....E.RESAASTLFIDPATRANLELAK.....TLSGSrdGSLLK.SLDRTMTSGG
  59 EDKNGSLA.....L.SALGGAIYYLRQAFLDe10feS.....LPYCDFSNVNEK.QHMVLDAAAL
  60 PVICSLAA.....I.IKYLKEFNLEKMlsKPENFKQL.....SSKmEFMTINGT.TLRNLEILQN
  61 KFLELLSD.....D.SNfGQFELTTFDFSQYMKLDIA.....AVRALNLFQGSV.EDttgsQSLA
  62 DNyGNFTI.....R.RYDIGGFMRLDSAAMRALNVME.....SKTDAnknFSLF.GLMNRTCTaG
  63 PVICSLAA.....I.IKYLKEFNLEKMlsKPENFKQL.....SSKmEFMTINGT.TLRNLEILQN
  64 LLsNIDKI.....D.INNDSSYMFLDDVTQVNLELVK.....NNNDFssqYSLY.SVLNDCKTAM
  65 ALSAFGAI.....F.WYLRDSLIDVDmlSMRNVTIYN.....Sn15wnGKNLIL.DGTALENLNI
  66 EDVVQYAA.....I.DYMKMDFYAKRNLELTESIRLKskk..GTLLWLMDETKT.PMGARRLKQW
  67 YLDLVNDA.....G.NlGHYEIKQLDLNRFVHLDSAA.....VAALNIMPKPGT.Hps8rwQSVL
  68 LGILHDPS.....NfGQYQLYQHDLAQFMKLDAAALK.....ALNLMPGARDGaknMSLYGLLNH
  69 YLDLVNDA.....G.NlGHYEIKQLDLNRFVHLDSAA.....VAALNIMPKPGT.Hps8rwQSVL
  70 LSIICLDM.....A.ISYLMEFSLEDLfvASNFYQPF.....DSISSMVLSKQA.LEGLELFVNQ
  71 LSIICLDM.....A.ISYLMEFSLEDLfvASNFYQPF.....DSISSMVLSKQA.LEGLELFVNQ
  72 ALKALGQC.....I.FFIHKCKLEPKvlPMARYQLYV.....Pp16lrRSHMVL.DATTLSNLRI
  73 KIQLSPSL.....I.RLVSKLYSHMVEYNNEQVmlIP.....SIYSPFASKIHM.LLDPNSLQSL
  74 TVQALALT.....F.CHLKQFGFERIlyQGASFRSLS.....SNTEMTLSANTL.QQLEVVKNNS
  75 DNyGNFTI.....R.RYDIGGFMRLDSAAMRALNVME.....SKTDAnknFSLF.GLMNRTCTaG
  76 KIQLSPSL.....I.RLVSKLYSHMVEYNNEQVmlIP.....SIYSPFASKIHM.LLDPNSLQSL
  77 SKLSMGAC.....N.ALIGYLQLLSEQDQvGKYELVE.....HKLKEFMKLDAS.AIKALNLFPQ
  78 SKLSMGAC.....N.ALIGYLQLLSEQDQvGKYELVE.....HKLKEFMKLDAS.AIKALNLFPQ
  79 KFLELLSD.....D.SNfGQFELTTFDFSQYMKLDIA.....AVRALNLFQGSV.EDttgsQSLA
  80 ADRLQNSHp....N.IQPPIRVSLNEYMIIGESAMKG.....LEIRSSLYQNrytGSLLHAINKT
  81 LSRLKLED.....VlkHGDIFPYQVYRGCLRIDGQTM.....VNLEIFNNSCDGvlqGPLNKYLE
  82 YLDLVNDA.....G.NlGHYEIKQLDLNRFVHLDSAA.....VAALNIMPKPGT.Hps8rwQSVL
  83 TNyGNYTI.....E.KYNLNCYMRLDSAAVRALNIAE.....GKTDVnknFSLF.GLMNRTCTvG
  84 LSRLKLED.....VlkHGDIFPYQVYRGCLRIDGQTM.....VNLEIFNNSCDGgpsGTLYKYLD
  85 NALLRYLG.....P.ALLNpd8re-NtsRKLHLYHHN.....LEQYMRLDIAAV.RSLNLLPPPN
  86 NALLRYLG.....P.ALLNpd8re-NtsRKLHLYHHN.....LEQYMRLDIAAV.RSLNLLPPPN
  87 TVQALALT.....F.CHLKQFGFERIlyQGASFRSLS.....SNTEMTLSANTL.QQLEVVKNNS
  88 HLTRLMLH.....D.AlkNGEVLPYHVYKTCLRMDGQ.....TLVNLEIFINNF.NGgssGTLYK
  89 HLTRLMLH.....D.AlkNGEVLPYHVYKTCLRMDGQ.....TLVNLEIFINNF.NGgssGTLYK
  90 TVQALALT.....F.CHLKQFGFERIlyQGASFRSLS.....SNTEMTLSANTL.QQLEVVKNNS
  91 LIYVSNHL.....P.DFSiNFQIPQRQLATAIMQIDS.....RTSTALELHSTV.RDNnkkGSLL
  92 KFLELLSD.....D.SNfGQFELTTFDFSQYMKLDIA.....AVRALNLFQGSV.EDttgsQSLA
  93 LIYVSNHL.....P.DFSiNFQIPQRQLATAIMQIDS.....RTSTALELHSTV.RDNnkkGSLL
  94 ILHSNAAD.....E.YsisEKYSIFNYGTHGNMLIDS.....CAVEALELFQLN.YNYle6nnLT
  95 LVSNIIDN.....F.DATNhRAFYLKHTIPSTFMKLD.....TAAIQALHIIHQ.KPEArgslpT
  96 KFLELLSD.....D.SNfGQFELTTFDFSQYMKLDIA.....AVRALNLFQGSV.EDttgsQSLA
  97 ve7yd-Vgv....P.ILGFKKFVLTHLVSIDQDTYSV.....LQIFKSESHPs1.2egLSLFGIL
  98 ve7yd-Vgv....P.ILGFKKFVLTHLVSIDQDTYSV.....LQIFKSESHPs1.2egLSLFGIL
  99 ADRLQNSHp....N.IQPPIRVSLNEYMIIGESAMKG.....LEIRSSLYQNrytGSLLHAINKT
 100 vt7lsV-ts....P.IKSIKTFTLGNLVEIDFNTIQA.....LDILPKETENkk.7qgRSLYQLM
 101 vt7lsV-ts....P.IKSIKTFTLGNLVEIDFNTIQA.....LDILPKETENkk.7qgRSLYQLM
 102 VYapKSLK.....I.CFQGSEQTAMIDSSSAQNLELL.....INNQDYrnnHTL.FGVLNYTKTP
 103 ve8nvS-v.....P.ILGFKKFMLTHLVNIDQDTYSV.....LQIFKSESHPs1.2egLSLFGIL
 104 VYapKSLK.....I.CFQGSEQTAMIDSSSAQNLELL.....INNQDYrnnHTL.FGVLNYTKTP
 105 ve8nvS-v.....P.ILGFKKFMLTHLVNIDQDTYSV.....LQIFKSESHPs1.2egLSLFGIL
 106 ve8nvS-v.....P.ILGFKKFMLTHLVNIDQDTYSV.....LQIFKSESHPs1.2egLSLFGIL
 107 ssrnl--naf...R.KLRIQFEGTENTMLIDSKTVRG.....LELVENKLDKng.ISLWKFLDTT
 108 ssrnl--naf...R.KLRIQFEGTENTMLIDSKTVRG.....LELVENKLDKng.ISLWKFLDTT
 109 vt7lsV-ts....P.IKSIKTFTLGNLVEIDFNTIQA.....LDILPKETENkk.7qgRSLYQLM
 110 LIkNLQLP.....E.CYNSvvsPLNLILCNRAEYQLD.....LLSKRGKLGGLL.NLIDYCSTAM
 111 IHETRCVF.....FrvKSLRIKEMGVNDTCMIDFVSW.....ESLEIVDADDASk10qkRTLMSV
 112 --------.....-.-----DTAALENLELLENTRTGgls..GTLYAQLNHCVT.GFGKRLLKRW
 113 --------.....-.----------------------.....------------.----------
 114 --------.....-.----------------------.....------------.----------
 115 --------.....-.----------------------.....------------.----------
 116 --------d....V.IHGIRYIDIRDRMVLDENTISA.....LHIFPTAHKLg1.0gfFSVFELF
 117 --------.....-.--dVIHGIRYIDIRDRMVLDEN.....TISALHIFPTAH.KLg10gfFSV
 118 --------.....-.----------------------.....------------.----------
 119 --------.....-.----------------------.....------------.----------


            300            310            320               330       3
             |              |              |                 |        
   1 LRHPLLDRGPLEARLDRV.....EGFV.....REGALREGVR...R.....LLYRLADLERLATR
   2 LRHPLLDRGPLEARLDRV.....EGFV.....REGALREGVR...R.....LLYRLADLERLATR
   3 SRMLKRWLHMPVRDTRVL.....LERQ.....QTIGALQ---...D.....FTAELQPVLRQVGD
   4 SRMLKRWLHMPVRDTRVL.....LERQ.....QTIGALQ---...D.....FTAGLQPVLRQVGD
   5 SRMLKRWLHMPVRHTRVL.....LERQ.....QTIGALQ---...D.....FTAELQPVLRQVGD
   6 LRHPLLERGPLEARLDRV.....ERFV.....REGALREGVR...R.....LLFRLADLERLATR
   7 LRHPLLERGPLEARLDRV.....ERFV.....REGALREGVR...R.....LLFRLADLERLATR
   8 SRLLKRWIHQPVRDVEKL.....KQRQ.....QSIAEIL-NF...D.....LVDELQPYLQLVGD
   9 SRLLGRWLNRPLRDRAVL.....EARQ.....DTVACLLQD-...Y.....RFESLQPQLKEIGD
  10 SRLMSRWLNRPLRDRAVL.....EARQ.....ESIACLL-ER...Y.....RFENLQPQLKEIGD
  11 SRLMSRWLNRPLRDRAVL.....EARQ.....ESIACLL-ER...Y.....RFENLQPQLKEIGD
  12 SRMLKRWIHQPMRDNATL.....NQRL.....DAITELK-ET...A.....LYGELHPVLKQIGD
  13 LRHPLLERGPLEARLDRV.....ERFV.....REGALREGVR...R.....LLFRLADLERLATR
  14 SRMLKRWLHMPVRNTDIL.....RERQ.....QTIGALQ---...D.....TVSELQPVLRQVGD
  15 LRHPLLERGPLEARLDRV.....ERFV.....REGALREGVR...R.....LLFRLADLERLATR
  16 RLGKKWILHPLVDRKQIE.....ERLK.....AVERLVNDRV...S.....LEEMRNLLSNVRDV
  17 ALLNKCKTPQGQRLVNQW.....IKQP.....LMDKNRIEER...L.....NLVEAFVEDAELRQ
  18 ALLNKCKTPQGQRLVNQW.....IKQP.....LMDKNRIEER...L.....NLVEAFVEDAELRQ
  19 ALLNKCKTPQGQRLVNQW.....IKQP.....LMDKNRIEER...L.....NLVEAFVEDAELRQ
  20 RLLKKWILHPLVDRKQIE.....ERLK.....AVERLVNDRV...S.....LEEMRNLLSNVRDV
  21 GSRALRRWLLQPLLDLKG.....IQAR.....QDTIQELYHH...P.....ALRQDLRQLLRQIY
  22 GSRALRRWLLQPLLDLKG.....IQAR.....QDTIQELYHH...P.....ALRQDLRQLLRQIY
  23 ALLNKCKTAQGQRLVNQW.....IKQP.....LMDRNRIEER...L.....NLVEAFVEDSELRQ
  24 ALLNKCKTAQGQRLVNQW.....IKQP.....LMDRNRIEER...L.....NLVEAFVEDSELRQ
  25 GTNGsteGTLLERVDTCH.....TPFG.....KRLLKQWLCA...P.....LCNHYAINDRLDAI
  26 GTNGsteGTLLERVDTCH.....TPFG.....KRLLKQWLCA...P.....LCNHYAINDRLDAI
  27 GTNGsteGTLLERVDTCH.....TPFG.....KRLLKQWLCA...P.....LCNHYAINDRLDAI
  28 GTNGsteGTLLERVDTCH.....TPFG.....KRLLKQWLCA...P.....LCNHYAINDRLDAI
  29 SRMLKRWLHMPVRNTDIL.....RERQ.....QTIGALQ---...D.....TVSELQPVLRQVGD
  30 GTNGsteGTLLERLDTCH.....TPFG.....KRLLKQWLCA...P.....LCSPSAISDRLDAV
  31 AFLNKCKTAQGQRLVSQW.....IKQP.....LMDKNRIEER...L.....NLVEAFVEDSELRR
  32 GTNGsteGTLLERVDTCH.....TPFG.....KRLLKQWLCA...P.....LCNHYAINDRLDAI
  33 GTNGsteGNLLERLDTCH.....TPFG.....KRLLKQWLCA...P.....LCSPSAISDRLDAV
  34 IHRPLIDKERIVQRQEVV.....QVFL.....DHFFERSDLT...D.....SLKGVYDIERLASR
  35 GGRLLRNTLINPFYDLKE.....ITLR.....QDSVEFFLQQ...A.....DLRKILKRQLSCVR
  36 SRLLALWLHHPLRNRAHI.....RARQ.....EAVAALE---...S.....QYKPLQCRLKSIAD
  37 IDRPLIRVNQIEERQEMV.....ETLM.....SHFFEREDLR...E.....RLKEVYDLERLAGR
  38 SRLLALWLHHPLRNRAHI.....RARQ.....EAVAALE---...S.....QYKPLQCRLKNIAD
  39 GRLLRRWLHRPLRLREVV.....RQRH.....AAVGSMI-DR...D.....LDNKLMETFRRLGD
  40 GGRLLRQILISPFYNPKE.....ILVR.....QDAVEFFLRQ...V.....TLRKNIKTYLCQVR
  41 DMktkGSLLWVLDHTKTS.....FGRR.....KLKNWVTQPL...L.....KLREINARLDAVSD
  42 DMktkGSLLWVLDHTKTS.....FGRR.....KLKNWVTQPL...L.....KLREINARLDAVSD
  43 DMktkGSLLWVLDHTKTS.....FGRR.....KLKNWVTQPL...L.....KLREINARLDAVSD
  44 RRRLRFRLLNPFRSIERI.....RKVQ.....EAVEELINKR...E.....VLNEIRKTLEGMSD
  45 IDRPLIRVNQIEERQEMV.....ETLM.....SHFFEREDLR...E.....RLKEVYDLERLAGR
  46 GGRLLRQILISPFYNPKE.....ILVR.....QDAVEFFLRQ...V.....TLRKNIKTYLCQVR
  47 GGRLLRNTLVNPFYDLKE.....ITLR.....QDSVEFFLKQ...E.....PLRKTLKRHLSCVR
  48 GLLNKCKTPQGQRLVNQW.....IKQP.....LMDKNRVEER...L.....NLVEAFVMDVELRQ
  49 RRRLKFRLLSPFRSREKI.....ERIQ.....EGVQELKENR...E.....ALLKIRQILEGMAD
  50 dkGTLFKLFNRAITPMGK.....RMMK.....KWLMHPLLRK...N.....DIESRLDSVDSLLQ
  51 dkGTLFKLFNRAITPMGK.....RMMK.....KWLMHPLLRK...N.....DIESRLDSVDSLLQ
  52 ALLNKCKTPQGQRLVNQW.....IKQP.....LMDKNRIEER...L.....NLVEAFVEDAELRQ
  53 DMktkGSLLWVLDHTKTS.....FGRR.....KLKNWVTQPL...L.....KLREINARLDAVSD
  54 VTTQGGRLLYHFLSSPLT.....NIAK.....INHRLNITEF...F.....YSNLGIVTRIRELL
  55 GgseGTLFHLLCRCVTPF.....GKRL.....FHTWLCHPLR...S.....GTAINARLDVVELI
  56 GTRLLRYWLHHPLRSQEE.....IQKR.....LSAVVFFHHR...P.....HILKTLRATLSCVR
  57 ENSRNGgysGTLYAQLNQ.....CITA.....SGKRLLKTWL...A.....RPLYNTELIKERQD
  58 ARLLAERLMSPLTDPERI.....NQRL.....DSIEVLADQP...R.....FTTDVRDALRRAPD
  59 ENLEIFENSRNGgysGTL.....YAQL.....NQCITASGKR...L.....LKTWLARPLYNTEL
  60 QTDMktkGSLLWVLDHTK.....TSFG.....RRKLKKWVTQ...P.....LLKLREINARLDAV
  61 ALLNKCKTPQGQRLVNQW.....IKQP.....LMDKNRIEER...L.....NLVEAFVEDAELRQ
  62 MGKRLLHMWLKQPLVDLN.....EIKT.....RLDIVQCFVE...E.....AGLRQDLRQHLKRI
  63 QTDMktkGSLLWVLDHTK.....TSFG.....RRKLKKWVTQ...P.....LLKLREINARLDAV
  64 GKRLLREFILNPILNISE.....INTR.....LDHVEFFCKN...I.....SLTVTLRETFINIW
  65 VPNGRDShlTSLYYVINK.....CSTP.....FGRRLLRSWL...L.....QPTCDPKKLEQRQK
  66 IDRPLISKEQIEARLDIV.....DEFS.....AHFIERDTLR...T.....YLNQVYDIERLVGR
  67 GVLDHCRTPQGHRLMGQW.....VKQP.....LRSRNILNDR...H.....NIVQCLLESPDTME
  68 CKTPVGSRLLSQWLKQPL.....MNAE.....EIEKRQQLVE...A.....FANDTELRQSMQeE
  69 GVLDHCRTPQGHRLMGQW.....VKQP.....LRSRNILNDR...H.....NIVQCLLESPDTME
  70 TDHtpvGSLFWVLDRTYT.....RFGQ.....RMLQRWLQKP...L.....VDKENIIERLDAVE
  71 TDHtpvGSLFWVLDRTYT.....RFGQ.....RMLQRWLQKP...L.....VDKENIIERLDAVE
  72 I---GEEHSLLSTLDHCC.....TKFG.....KRLLHHWLCA...P.....SCDVSVIKERQDAI
  73 DIFTHDGGKGSLFWLLDH.....TRTS.....FGLRMLREWI...L.....KPLVDVHQIEERLD
  74 DGsesGSLFHNMNHTLTV.....YGSR.....LLRHWVTHPL...C.....DRNLISARLDAVs1
  75 MGKRLLHMWLKQPLVDLN.....EIKT.....RLDIVQCFVE...E.....AGLRQDLRQHLKRI
  76 DIFTHDGGKGSLFWLLDH.....TRTS.....FGLRMLREWI...L.....KPLVDVHQIEERLD
  77 GPQNp21kvTSLFQLLNH.....CKTN.....AGVRLLNEWL...K.....QPLTNIDEINKRHD
  78 GPQNp21kvTSLFQLLNH.....CKTN.....AGVRLLNEWL...K.....QPLTNIDEINKRHD
  79 ALLNKCKTPQGQRLVNQW.....IKQP.....LMDKNRIEER...L.....NLVEAFVEDAELRQ
  80 VTKSGSRLLTRRLCAPST.....NIVE.....INNRLDLVEK...F.....KLLPELCSKVINLL
  81 NCVSPTGKRLLRNWICHP.....LKDV.....ESINKRLDVV...E.....EFTANSESMQITGQ
  82 GVLDHCRTPQGHRLMGQW.....VKQP.....LRSRNILNDR...H.....NIVQCLLESPDTME
  83 MGKRLLNRWLKQPLLDVN.....EINN.....RLDMVQAFVE...D.....PELRQGLRQQLKRI
  84 NCVSPTGKRLLRNWICHP.....LKDV.....ESINKRLDVV...E.....EFTANSESMQITGQ
  85 GNahktMSLYGLLNHCRT.....AMGA.....RNLRRWIVQP...L.....LDAKSIERRHDLVS
  86 GNahktMSLYGLLNHCRT.....AMGA.....RNLRRWIVQP...L.....LDAKSIERRHDLVS
  87 DGsesGSLFHNMNHTLTV.....YGSR.....LLRHWVTHPL...C.....DRNLISARLDAVs1
  88 HLNHCVTASGKRMLRRWI.....CHPL.....KDIDAINKRL...D.....VVEGFIQNCGLGPT
  89 HLNHCVTASGKRMLRRWI.....CHPL.....KDIDAINKRL...D.....VVEGFIQNCGLGPT
  90 DGsesGSLFHNMNHTLTV.....YGSR.....LLRHWVTHPL...C.....DRNLISARLDAVs1
  91 SSIRRTVTPSGTRLLSQW.....LSGP.....SLDLKEIKKR...Q.....KIVAFFKDNRDITE
  92 ALLNKCKTPQGQRLVNQW.....IKQP.....LMDKNRIEER...L.....NLVEAFVEDAELRQ
  93 SSIRRTVTPSGTRLLSQW.....LSGP.....SLDLKEIKKR...Q.....KIVAFFKDNRDITE
  94 LYNVLNKCKTLPGEKLLR.....DWLS.....RPLCQIDHIN...E.....RLDIVEALFENQTI
  95 SVYSWLNRCVTGMGSRMM.....RQWL.....LQPLRNAEDI...N.....QRLSLVELMVEDSI
  96 ALLNKCKTPQG-------.....----.....----------...-.....--------------
  97 NRCRCKWGQKLLRLWFTR.....PTRE.....LRELNSRLDV...I.....QFFLmpQNLDMAQM
  98 NRCRCKWGQKLLRLWFTR.....PTRE.....LRELNSRLDV...I.....QFFLmpQNLDMAQM
  99 VTKSGSRLLTRRLCAPST.....NIVE.....INNRLDLVEK...F.....KLLPELCSKVINLL
 100 DKCRSTVGKKCLRKWFRN.....PTTD.....RDDLVSRQKC...V.....HYFKqdWNAEVTAK
 101 DKCRSTVGKKCLRKWFRN.....PTTD.....RDDLVSRQKC...V.....HYFKqdWNAEVTAK
 102 GGSRRLRSNILEPLVDIE.....TINM.....RLDCVQELLQ...D.....EELFFGLQSVISRF
 103 NRCHCKWGEKLLRLWFTR.....PTHD.....LGELSSRLDV...I.....QFFLlpQNLDMAQM
 104 GGSRRLRSNILEPLVDIE.....TINM.....RLDCVQELLQ...D.....EELFFGLQSVISRF
 105 NRCHCKWGEKLLRLWFTR.....PTHD.....LGELSSRLDV...I.....QFFLlpQNLDMAQM
 106 NRCHCKWGEKLLRLWFTR.....PTHD.....LGELSSRLDV...I.....QFFLlpQNLDMAQM
 107 STKMGQRSLRNSILQPLT.....DRGS.....IEMRLEALEE...L.....KANDDLLQKLRLEM
 108 STKMGQRSLRNSILQPLT.....DRGS.....IEMRLEALEE...L.....KANDDLLQKLRLEM
 109 DKCRSTVGKKCLRKWFRN.....PTTD.....RDDLVSRQKC...V.....HYFKqv7kvEYRNL
 110 GKRLLKFRLLNPITDYSE.....LNLR.....YKDISIFKRL...L.....NQKIFDNSELKCIK
 111 LNHTVTTNGYRLLRSSVL.....QPST.....DVYLIQSRQE...A.....IEELIGKPQLKDKL
 112 IAKPLYDCREILRRQSAV.....ATFKg....VGQDCAAQFR...K.....DLSRLPDMERLLAR
 113 ------------------.....----.....----------...-.....--------------
 114 ------------------.....----.....---GIGVDVS...P.....VMIKVVDAAVQKAR
 115 ------------------.....----.....----------...-.....--------------
 116 NQVSSDYARRILKSWLIN.....PLTN.....KKRIETRYSI...I.....RTLLdkQNAIIFSD
 117 FELFNQVSSDYARRILKS.....WLIN.....PLTNKKRIET...R.....YSIIRTLLdkQNAI
 118 ------------------.....----.....----------...-.....--------------
 119 ------------------.....----.....----------...-.....--------------


      40            350        360       370            380       390  
      |              |          |         |              |         |  
   1 LE.....LGRASPKDLGAL.RRSLQILPELRALLGEEVG.....LPDLSPLKEELEAALVEDPP.
   2 LE.....LGRASPKDLGAL.RRSLQILPELRALLGEEVG.....LPDLSPLKEELEAALVEDPP.
   3 LE.....RILARLALRTAR.PRDLARMRHAFQQLPELRA.....QLETVDSap9ekMGEFAELR.
   4 LE.....RILARLALRTAR.PRDLARMRHAFQQLPELRA.....QLETVDSap9ekMGEFAELR.
   5 LE.....RILARLALRTAR.PRDLARMRHAFQQLPELRA.....QLETVDSap9ekMGEFAELR.
   6 LE.....LSRASPRDLAAL.RRSLEILPELKGLLGEEVG.....LPDLSGLLEELRAALVEDPP.
   7 LE.....LSRASPRDLAAL.RRSLEILPELKGLLGEEVG.....LPDLSGLLEELRAALVEDPP.
   8 ME.....RILARVALRSAR.PRDLTRLRTALEQIPALRA.....IVQQKTPpf9sqIADFSEQC.
   9 VE.....RILARIGLRNAR.PRDLARLRDALAALPQLQT.....ALSPLEAph9gnIRTYPELA.
  10 LE.....RILARIGLRNAR.PRDLARLRDALAALPDLQN.....AMTELEAph9ttIGTYPELA.
  11 LE.....RILARIGLRNAR.PRDLARLRDALAALPDLQN.....AMTELEAph9ttIGTYPELA.
  12 IE.....RILARLALRSAR.PRDLARLRHAMQQLPELHS.....VMSELKQph9thAEPMDELC.
  13 LE.....LSRASPRDLAAL.RRSLEILPELKGLLGEEVG.....LPDLSGLLEELRAALVEDPP.
  14 LE.....RTPC----ASGA.AQPSARSRPNASRLPAAAE.....LHAQLETv12kkMGDFAELR.
  15 LE.....LSRASPRDLAALrRRSLEILPELEGLLGEEVG.....LPDLSGLLEELRAALVEDPP.
  16 ER.....IVSRVEYNRSVP.RDLVALRETLEIIPKLNEV.....LSTFGVfkkLAFPEGLVDLL.
  17 TL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGINQLPNVIQALEKHEGk.
  18 TL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGINQLPNVIQALEKHEGk.
  19 TL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGINQLPNVIQALEKHEGk.
  20 ER.....IVSRVEYNRSVP.RDLVALRETLEIIPKLNEV.....LSTFGVfkkLAFPEGLVDLL.
  21 DL.....ERLTGRIGANTA.SARDVYGLASSLVRLTDLA.....ELAQEGHSpy9tvPPELEEL.
  22 DL.....ERLTGRIGANTA.SARDVYGLASSLVRLTDLA.....ELAQEGHSpy9tvPPELEEL.
  23 SL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGINQLPSVIQALEKYEGr.
  24 SL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGINQLPSVIQALEKYEGr.
  25 ED.....LMVVPDKISEVV.ELLKKLPDLERLLSKIHn2.....3ttYSKKKIIDFLSALEGFK.
  26 ED.....LMVVPDKISEVV.ELLKKLPDLERLLSKIHn2.....3ttYSKKKIIDFLSALEGFK.
  27 ED.....LMVVPDKISEVV.ELLKKLPDLERLLSKIHn2.....3ttYSKKKIIDFLSALEGFK.
  28 ED.....LMVVPDKISEVV.ELLKKLPDLERLLSKIHn2.....3ttYSKKKIIDFLSALEGFK.
  29 LE.....RTPC----ASGA.AQPSARSRPNASRLPAAAE.....LHAQLETv11vkKWAISPSC.
  30 ED.....LMAVPDKVTEVA.DLLKKLPDLERLLSKIHn2.....3ttYSKKKIIDFLSALEGFK.
  31 AL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGVKQLPNVIQALEKYQGr.
  32 ED.....LMVVPDKISEVV.ELLKKLPDLERLLSKIHn2.....3ttYSKKKIIDFLSALEGFK.
  33 ED.....LMAVPYKVTEVA.DLLKKLPDLERLLSKIHn2.....3ttYSKKKIIDFLSALEGFK.
  34 VS.....FGKTNPKDLLQL.ATTLSSVPRIRAILEGMEQpt...9aqLDAIPELESLISAAIAP.
  35 DL.....ERLATKISTSLA.TPKDIGTLRDSLLSCTHIA.....DNLQNCALp10liAPPLCSL.
  36 IE.....RIAARIAVGNAR.PRDLAALRDSLFALSEIEL.....SAECSSLlg7avFPENLSTA.
  37 VA.....FGNVNARDLIQL.KESLKQVPGIKQLVASLAHdk...9krIDPCGDVLELLEEALYE.
  38 IE.....RIAARIAVGNAR.PRDLASLRDSLFELAQIDL.....SANGSSLle7avFPENLSTA.
  39 ME.....RILTRVALRSAR.PRDISTLRDSLSLLPRLRE.....LLNASDSpr9aeLGEHDSTA.
  40 DI.....ERLMTKVTTGLA.GPRDIGTLRDSFSAGAQIY.....EQLASATLp10slDTKLASL.
  41 VLh....SESSVFEQIENL.LRKLPDVERGLCSIYHKKC.....STQEFFLIVKSLCQLKSELQ.
  42 VLh....SESSVFEQIENL.LRKLPDVERGLCSIYHKKC.....STQEFFLIVKSLCQLKSELQ.
  43 VLh....SESSVFEQIENL.LRKLPDVERGLCSIYHKKC.....STQEFFLIVKSLCQLKSELQ.
  44 LE.....RLVSRISSNMAS.PRELIHLKNSLRKAEELRK.....ILSLLDSei9gsLLNLNKVA.
  45 VA.....FGNVNARDLIQL.KESLKQVPGIKQLVASLAHdk...9krIDPCGDVLELLEEALYE.
  46 DI.....ERLMTKVTTGLA.GPRDIGTLRDSFSAGAQIY.....EQLASATLp10slDTKLASL.
  47 DL.....ERLATKISTTLA.SPKDIGMLRDSLLSCMHIA.....HDLQSYTLp10liSSSLKSL.
  48 CL.....QeDLLRRFPDLN.RLAKKFQRQTANLQDCYRL.....YQAVNHLPTVVQAIEKYEGt.
  49 LE.....RLVSKISSNMAT.PRELVYLKNSLKKVEELRL.....LLLELKApi9qnFEDTKKII.
  50 DI.....TLREQLEITFSK.LPDLERMLARIHSRTIKVK.....DFEKVITAFETIIELQDSLK.
  51 DI.....TLREQLEITFSK.LPDLERMLARIHSRTIKVK.....DFEKVITAFETIIELQDSLK.
  52 TL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGINQLPNVIQALEKHEGk.
  53 VLh....SESSVFEQIENL.LRKLPDVERGLCSIYHKKC.....STQEFFLIVKSLCQLKSELQ.
  54 KN.....TSDIERCLTRIT.MNRSSGRDLLSIKYTLETA.....KTIKGLFSESYGl13kpLSG.
  55 AD.....NPVIRDTIWGFL.HKLPDLERLISRVHAGRSK.....PADFVRVLEGFQRINSAFDQ.
  56 DV.....ERLVARVALEKA.HGRDLLALKESLRAILTFR.....SLERESPFp10gdTPVLQEL.
  57 AV.....AILRgENLPYSL.EFRKSLSRLPDMERLIARM.....Fs18edTAKKQVQEFISTLR.
  58 MP.....RALSRLALGRGG.PRDLGAIQAGMRAAAAISA.....LLSGAELs11aiAALPGELL.
  59 IK.....ERQDAVAILRgE.NLPYSLEFRKSLSRLPDME.....RLIARMFs18edTAKKQVQE.
  60 SE.....VLhSESSVFGQI.ENHLRKLPDIERGLCSIYH.....KKCSTQEFFLIVKTLYHLKS.
  61 TL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGINQLPNVIQALEKHEGk.
  62 SD.....VERLLRSLERRR.GGLQHIIKLYQSAIRLPFI.....KTAMQQYTGe19sdQDHLGK.
  63 SE.....VLhSESSVFGQI.ENHLRKLPDIGRGLCSIYH.....KKCSTQEFFLIVKTLYHLKS.
  64 DI.....ERIISRIQMKRY.IKKDFLFIEKALSVFFTVK.....KLFDKHNFdywNFDKFEEDS.
  65 AI.....KWLVspDASSFM.TTATATLKKIPDLDRLLQK.....IHt23ikTNQKKIAELLAAI.
  66 VS.....YGNVNARDLIQL.KHSISEIPNIKALLNSMNQnt...8nqLEPLDDLLDILEQSLVE.
  67 TL.....SlDYLKRIPDIL.MLTKKLMRRKANLQDLFRI.....YQVILRTPKILKVLHELDNs.
  68 HL.....RSIPDLYRLSKR.FQRGKATLEDVVRAYQVVI.....RLPGFIGTLEGVMDe18elS.
  69 TL.....SlDYLKRIPDIL.MLTKKLMRRKANLQDLFRI.....YQVILRTPKILKVLHELDNs.
  70 EL.....AfNSNSQVQAIR.KMLYRLPDLEKGLSRIYy1.....3fsKNSYSCFKSALLRRLIQ.
  71 EL.....AfNSNSQVQAIR.KMLYRLPDLEKGLSRIYy1.....3fsKNSYSCFKSALLRRLIQ.
  72 GE.....LIRMPTELQEVR.ALLAPMPDFERNLAQIHl2.....4klYNKQKLQGFMAVLKGFN.
  73 AI.....ECITseiNNSIF.FESLNQMLNHTPDLLRTLN.....RIMYGTTSRKEVYFYLKQIT.
  74 6ls....SELVEEGSERAI.VSPe11ltAMSRSSDIQRG.....ITRIFHRTAKATEFIAVMEA.
  75 SD.....VERLLRSLERRR.GGLQHIIKLYQSTIRLPFI.....KTAMQQYTGe19sdQDHLGK.
  76 AI.....ECITseiNNSIF.FESLNQMLNHTPDLLRTLN.....RIMYGTTSRKEVYFYLKQIT.
  77 LV.....DYLIDQIELRQM.LTsEYLPMIPDIRRLTKKL.....N-KRGNLEDVLKIYQFSKRI.
  78 LV.....DYLIDQIELRQM.LTsEYLPMIPDIRRLTKKL.....N-KRGNLEDVLKIYQFSKRI.
  79 TL.....QeDLLRRFPDLN.RLAKKFQRQAANLQDCYRL.....YQGINQLPNVIQALEK----.
  80 KK.....SNDTHRILQHLL.MGRGNSYDLLKMADNFSIT.....KEIHSLLSPLESs10lnMHP.
  81 YL.....HKLPDLERLLGR.IKSSVRSSASVLPALLGKK.....VLKQRVKAFGQIVKg11laL.
  82 TL.....SlDYLKRL----.-------------------.....--------------------.
  83 SD.....IDRLTHSLRKKS.ANLQPVVKLYQSCSRIPYI.....KGILQQYNGq19maKNRFGR.
  84 YL.....HKLPDLERLLGR.IKSSVRSSASVLPALLGKK.....VLKQRVKAFGQIVKg11laL.
  85 AL.....VEDAEARQLLLdddHLLRSIPDIPKLCRRLTR.....GSASLEDVVRIYQMAKALPK.
  86 AL.....VEDAEARQLLLdddHLLRSIPDIPKLCRRLTR.....GSASLEDVVRIYQMAKALPK.
  87 6ls....SELVEEGSERAI.VSPe11ltAMSRSSDIQRG.....ITRIFh23pgSSSPGLRVLN.
  88 TL.....GYLQKIPDLERL.LGQVR----STVGLSSLLQ.....LPFIGEKIIK----------.
  89 TL.....GYLQKIPDLERL.LGQVR----STVGLSSLLQ.....LPFIGEKIIK----------.
  90 6ls....SELVEEGSERAI.VSPe11ltAMSRSSDIQRG.....ITRIFh23pvSSSPGLRVLN.
  91 NL.....RTMLKKVNDLSR.ILQKFSFGRGEALELIQMA.....RSLEVSREIRKYLLNNTSlm.
  92 TL.....Q-----------.-------------------.....--------------------.
  93 TL.....RTMLKKVNDLSR.ILQKFSFGRGEALELIQMA.....RSLEVSREIRKYLLNNTSlm.
  94 RQ.....KLRdSILARMPD.CSQLARRLM-RKCTLQDLN.....RFYQAATLLETVEMQLIQLS.
  95 LR.....DALLsQVLRCCG.DMDRLNRKLQRRSIALKDL.....QSILTFVNTIPRAVQVLRTH.
  96 --.....------------.-------------------.....--------------------.
  97 LH.....RLLSHIKNVPLI.LKRMKLSHTKVSDWQVLYK.....TVYSALGLRDACRSLPQs12e
  98 LH.....RLLSHIKNVPLI.LKRMKLSHTKVSDWQVLYK.....TVYSALGLRDACRSLPQs12e
  99 KK.....SNDTHRILQHLL.MGRGNSYDLLKMADNFSIT.....KEIHSLLSPLESs10lnMHP.
 100 LS.....SILGRVKALNSV.FQKFQSGTAQLIHWECFVS.....TVNALVEILNIIRQTPIsk9s
 101 LS.....SILGRVKALNSV.FQKFQSGTAQLIHWECFVS.....TVNALVEILNIIRQTPIsk9s
 102 LD.....TEQLLSVLVqi9vnAAESKITNLIYLKHTLEL.....VDPLKIAMKNCNTp11leDK.
 103 LH.....RLLGHIKNVPLI.LKRMKLSHTKVSDWQVLYK.....TVYSALGLRDACRSLPQs12e
 104 LD.....TEQLLSVLVqi9vnAAESKITNLIYLKHTLEL.....VDPLKIAMKNCNTp11leDK.
 105 LH.....RLLGHIKNVPLI.LKRMKLSHTKVSDWQVLYK.....TVYSALGLRDACRSLPQs12e
 106 LH.....RLLGHIKNVPLI.LKRMKLSHTKVSDWQVLYK.....TVYSALGLRDACRSLPQs12e
 107 KS.....LPDLDKLFSRLLci7aiKPDQRINYVLLLKET.....LQSVKSLKDALNDQLIq13fn
 108 KS.....LPDLDKLFSRLLci7aiKPDQRINYVLLLKET.....LQSVKSLKDALNDQLIq13fn
 109 WE.....IFLNHSKFSPDS.EYLSEKIFl96fqSGTAQL.....IHWECFVSTVNALVEILNII.
 110 DL.....SSLHRQWAicassDTTLPPKKLSQIYHSYLFA.....CQLISKLTNNIQlpplvGPQ.
 111 RR.....TLSRAHELDRVI.AMCIqt9vrESEAKINQII.....KLMHTLKVIQGIRTLLHSAK.
 112 LFs....14vlYEDASKKL.LQQFTSALCGCQQMFHACS.....SISTl18kgLSNISSILDRF.
 113 --.....------------.-------------------.....--------------------.
 114 IG.....LRNARPRDLARL.RDALGALPELQNAMTELEAph...9aiTGTYPELASLLERAIID.
 115 --.....------------.-------------------.....--------------------.
 116 LS.....QSIKRCPDAFGF.INQLRSGKSTLGTWSKVAS.....FLEKGIAIFQLVSSLKLg16v
 117 IF.....SDLSQSIKRCPD.AFGFINQLRSGKSTLGTWS.....KVASFLEKGIAIFQLVSSLK.
 118 --.....------------.-------------------.....--------------------.
 119 --.....------------.-------------------.....--------------------.


                400       410        420       430              440    
                 |         |          |         |                |    
   1 ....LKVSEGGLIREGYDPDLDALR.AAHREGVAYFLELEERERERTG..IP.....TLKVGYNA
   2 ....LKVSEGGLIREGYDPDLDALR.AAHREGVAYFLELEERERERTG..IP.....TLKVGYNA
   3 ....DLLERAIIDTPPVLVRDGGVI.ASGYNEELDEWRALADGATDYL..ER.....LEVRERER
   4 ....DLLERAIIDTPPVLVRDGGVI.ASGYNEELDEWRALADGATDYL..ER.....LEVRERER
   5 ....DLLERAIIDTPPVLVRDGGVI.ASGYNEELDEWRALADGATDYL..ER.....LEVRERER
   6 ....LKVSEGGLIREGYDPDLDALR.RAHAEGVAYFLDLEAREKERTG..IP.....TLKVGYNA
   7 ....LKVSEGGLIREGYDPDLDALR.RAHAEGVAYFLDLEAREKERTG..IP.....TLKVGYNA
   8 ....DLLQRALIETPPLLIRDGGVI.AEGYNAELDEWRMLSDGATQYL..EN.....LEKRERES
   9 ....ELLRRAIIDNPPAVIRDGGVL.KQGYDAELDELLSLSENAGQFL..MD.....LEAREKAR
  10 ....ELLAKAIIDNPPAVIRDGGVI.KTGYDAELDELQALSENAGQFL..MD.....LEAREKAR
  11 ....ELLAKAIIDNPPAVIRDGGVI.KTGYDAELDELQALSENAGQFL..MD.....LEAREKAR
  12 ....DLLERAIKENPPVVIRDGGVI.ADGYSAELDEWRDLANGATEFL..ER.....LEAEERDR
  13 ....LKVSEGGLIREGYDPDLDALR.RAHAEGVAYFLDLEAREKERTG..IP.....TLKVGYNA
  14 ....DLLERAIIDAPPVLVRDGAVI.APGYHEELDEWRALADGATDYL..DR.....LEIRERER
  15 ....LKVSEGGVIREGYDPDLDALR.RAHADPVAYFLDLEVREKESTG..IP.....TLKVGYNA
  16 ....RKAIEDDPVGSPGEGKVIKRG.FSSELDEYRDLLEHAEERLKEF..EE.....KERERTGI
  17 ....17dlRSDFSKFQEMIETTLDM.D--QVENHEFLVKPSFDPNLSE..LR.....EIMNDLEK
  18 ....17dlRSDFSKFQEMIETTLDM.D--QVENHEFLVKPSFDPNLSE..LR.....EIMNDLEK
  19 ....17dlRSDFSKFQEMIETTLDM.D--QVENHEFLVKPSFDPNLSE..LR.....EIMNDLEK
  20 ....RKAIEDDPVGSPGEGKVIKRG.FSSELDEYRDLLEHAEERLKEF..EE.....KERERTGI
  21 ....GKYVLAHIVENPPLHIREGNL.IRSGVNPTLDEMRQSLEDDNQW..LA.....NLEVTERE
  22 ....GKYVLAHIVENPPLHIREGNL.IRSGVNPTLDEMRQSLEDDNQW..LA.....NLEVTERE
  23 ....17dlRSDFSKFQEMIETTLDM.D--QVENHEFLVKPSFDPNLSE..LR.....EVMDGLEK
  24 ....17dlRSDFSKFQEMIETTLDM.D--QVENHEFLVKPSFDPNLSE..LR.....EVMDGLEK
  25 ....VMCKIIGIMEEVADg21grFP.DLTVELNRWDTAFDHEK-ARKT..GL.....ITPKAGFD
  26 ....VMCKIIGIMEEVADg21grFP.DLTVELNRWDTAFDHEK-ARKT..GL.....ITPKAGFD
  27 ....VMCKIIGIMEEVADg21grFP.DLTVELNRWDTAFDHEK-ARKT..GL.....ITPKAGFD
  28 ....VMCKIIGIMEEVADg21grFP.DLTVELNRWDTAFDHEK-ARKT..GL.....ITPKAGFD
  29 ....ATSWNAPLLTRRRYWSRRRVI.APGYHEELDEWRALADGATDYL..DR.....LEIRERER
  30 ....VMCKVSGLLEEVAGg21grFP.DLTAELQRWDTAFDHEK-ARKT..GL.....ITPKAGFD
  31 ....17dlRSDFSKFQEKIETTLDM.D--QVENHEFLVKPSFDPNLSE..LR.....EVMDGLEK
  32 ....VMCKIIGIMEEVADg21grFP.DLTVELNRWDTAFDHEK-ARKT..GL.....ITPKAGFD
  33 ....VMCKVSGLLEEVAGg21grFP.DLTAELQRWDTAFDHEK-ARKT..GL.....ITPKAGFD
  34 ....EAPHVITDGGIIRTGFDETLD.KYRCVLREGTSWIAEIEAKERE..NS.....GISTLKID
  35 ....IKTLSTELIQELPLKVSEGNI.FANHYHPDLLRLRNIKENSKSW..IL.....EYQERIRN
  36 ....EQLRQAILPEPSVWLKDGNVI.NHGFHPELDELRRIQNHGDEFL..LD.....LEAKERER
  37 ....NPPLSVKEGNLIKDGYNQKLD.EYRDASRNGKDWIARLEQQERE..YT.....GIRSLKVG
  38 ....EQLRQAILPEPSVWLKDGNVI.NHGFHPELDELRRIQNHGDEFL..LD.....LEAKERER
  39 ....SLLVKAVAEQPPLKLTDGGVI.ASEYDVELDELRKLSNNADQFL..ID.....LETRERES
  40 ....IALLSKSLNGDLPLRVSDGNI.FVDEFHNDLKRLRHNQEHSQEW..IW.....EYQERIRK
  41 ....ALMPAVNs11alIVELLSPVE.HYLKVLNGPAAKVGDKTELFKD..LS.....DFPLIKKR
  42 ....ALMPAVNs11alIVELLSPVE.HYLKVLNGPAAKVGDKTELFKD..LS.....DFPLIKKR
  43 ....ALMPAVNs11alIVELLSPVE.HYLKVLNGPAAKVGDKTELFKD..LS.....DFPLIKKR
  44 ....DLIDKTLVDDPPLHVKEGGLI.KPGVNAYLDELRFIRENAEKLL..KE.....YEKKLKKE
  45 ....NPPLSVKEGNLIKDGYNQKLD.EYRDASRNGKDWIARLEQQERE..YT.....GIRSLKVG
  46 ....IALLSKSLNGDLPLRVSDGNI.FVDEFHNDLKRLRHNQEHSQEW..IW.....EYQERIRK
  47 ....IEALSTDLLQELPLKVSEGNI.FADHYHQDLLRLRNIKTNSKSW..IL.....EYQERIRQ
  48 ....17dlSSDFSKFQEMIETTLDM.D--QVENHEFLVKASFDPNLTE..LR.....EKMDELEK
  49 ....NDIEKTLVEDPPLHVKEGGLI.REGVNAYLDELRFIRDNAETYL..RE.....YEKKLRQE
  50 ....NNDLKGDVSKYISSFPEGLVE.AVKs10qkAINENIIVPQRGFD..IE.....FDKSMDRI
  51 ....NNDLKGDVSKYISSFPEGLVE.AVKs10qkAINENIIVPQRGFD..IE.....FDKSMDRI
  52 ....17dlRSDFSKFQEMIETTLDM.D--QVENHEFLVKPSFDPNLSE..LR.....EIMNDLEK
  53 ....ALMPAVNs11alIVELLSPVE.HYLKVLNGPAAKVGDKTELFKD..LS.....DFPLIKKR
  54 ....DAELYNLIHMSIREDAPNNLN.DGGIIKYEFHPKIAQLNDLINN..KK.....LHVEKLKD
  55 ....LREEFMe14qsAPNMKEELEA.WTRAFNWQK-ASEEGVFEPEIG..FE.....AEYDTSQK
  56 ....YGLLEQSIKEDCPVTLSDGNL.IKRGFSASLDELHRVRDNANEI..LK.....QYLAEERE
  57 ....GCETMAEACSSLRAILKh16qsLPNISSSIKYFKDAFDWVE-AH..NS.....GRVIPHEG
  58 ....ARLDATLAEELPLLKRDGGFV.REGASAELDEMRALRDQSRRVI..AG.....LQLQYCEE
  59 ....FISTLRGCETMAEACSSLRAI.LKh41qsLPNISSSIKYFKDAF..DW.....VE-AHNSG
  60 ....EFQAIIPAVNs14leIPELLS.PVEHYLKILNEQAAKVGDKTEL..FK.....DLSDFPLI
  61 ....17dlRSDFSKFQEMIETTLDM.D--QVENHEFLVKPSFDPNLSE..LK.....--------
  62 ....FIDLVECSVDLD--QLENGEY.MISSNYDTKLASLKDQKELLEQ..QI.....HELHKKTA
  63 ....EFQAIIPAVNs14leIPELLS.PVEHYLKILNEQAAKVGDKTEL..FK.....DLSDFPLI
  64 ....ISKVYFLINSAISSAPDELIK.RGYDLKLDNLKDLKINANKYID..QY.....LESERLLS
  65 ....DGFKLCNKLRKEYIKVQKe17qeMEEVDENIYFFEKMFDRST-A..MK.....DGKIVPNA
  66 ....EPPISVKDGGLFKVGFNTQLD.E---------------------..--.....--------
  67 ....14sfLKDLTGLKQMVEQVVDF.E--AIERGEYLVKASFDSRLME..LQ.....QMMTELYS
  68 ....DSLVKLQEMVETTVDLD--AL.DNHEFIIKPEFDDSLRIIRKKL..DR.....LRTDMDNE
  69 ....14sfLKDLTGLKQMVEQVVDF.E--AIERGEYLVKASFDSRLME..LQ.....QMMTELYS
  70 ....QLPSISSIIDHFLGmfDQKEA.ENNNKVDMFKDIDNFDLSEEPN..DV.....DYELAQEI
  71 ....QLPSISSIIDHFLGmfDQKEA.ENNNKVDMFKDIDNFDLSEEPN..DV.....DYELAQEI
  72 ....DLTKLPTMFHQCKTt15gsFP.DLSKELQYFATAFDHDA-AAKT..GV.....IAPQAGMD
  73 ....SFVDHFKMHQSYLSe32tqLP.HFLTMINVSAVMEKNSDKQVMD..FF.....NLNNYDCS
  74 ....ILLAGKQIQRLGIKQDs28vv.VDNAGKLLSALNKEAAVRGDLL..--.....DILITSSD
  75 ....FIDLVECSVDLD--QLENGEY.MISSSYDTKLASLKDQKELLEQ..QI.....HELHKKTA
  76 ....SFVDHFKMHQSYLSe32tqLP.HFLTMINVSAVMEKNSDKQVMD..FF.....NLNNYDCS
  77 ....PEIVQVFTSFLEd23hhVEPL.SKFEEMVETTVDLDA-YEENNE..FM.....IKVEFNEE
  78 ....PEIVQVFTSFLEd23hhVEPL.SKFEEMVETTVDLDA-YEENNE..FM.....IKVEFNEE
  79 ....---------------------.----------------------..--.....--------
  80 ....HDELKQLINNAVDENALmkqk.INEEEETEVIAQEAEEILQDEN..AQ.....VEIVKKSL
  81 ....QKESNMMSLLYKLCKLPILVG.KSGLELFLSQFEAAID------..--.....--------
  82 ....------KQMVEQVVDFE--AI.ERGEYLVKASFDSRLMELQQMM..TE.....LYSKMEEL
  83 ....FSSLVETAIDLA--QLENGEY.RISPLYSSDLGVLKDELSVVEN..HI.....NNLHVDTA
  84 ....QKESNMMSLLYKLCKLPILVG.KSGLELFLSQFEAAID------..--.....--------
  85 ....IVTVLDSLTSe17nhCKNLEK.LIELVETTIDLE--ALDSHQYI..IR.....AEFDEELL
  86 ....IVTVLDSLTSe17nhCKNLEK.LIELVETTIDLE--ALDSHQYI..IR.....AEFDEELL
  87 ....FLDEKFIAVMEAILLAGKQIQr35vvVDNAGKLLSALNKEAAVR..GD.....LL--DILI
  88 ....-----------------KRIK.TFIMLINGLRNGIDLLNDLQRA..DH.....GILA----
  89 ....-----------------KRIK.TFIMLINGLRNGIDLLNDLQRA..DH.....GILA----
  90 ....FLDEKFIAVMEAILLAGKQIQr35vvVDNAGKLLSALNKEAAVR..GD.....LL--DILI
  91 ....9sqITQLTESLNFEKNLIDDI.LKFLNEEELAKSQDAKQNADVT..RM.....LDIDVKDK
  92 ....---------------------.----------------------..--.....--------
  93 ....9sqITQLTESLNFEKNLIDDI.LKFLNEEELAKSQDAKQNADVT..RM.....LDIDVKDK
  94 ....Ea18teILKKVERFQVLCDEF.FDFDYEKENKEIRVRVDFVPEI..QE.....ISEKLEQM
  95 ....QGg14apLEDINEHFSNLRIL.ITATVDLSDENTTRINPEFDDE..LM.....ELEEQRKS
  96 ....---------------------.----------------------..--.....--------
  97 f...SDDLHHIASLIGKVVDFEE-S.LAENRFTVLPNIDPDIDAKKRR..LI.....GLPSFLTE
  98 f...SDDLHHIASLIGKVVDFEE-S.LAENRFTVLPNIDPDIDAKKRR..LI.....GLPSFLTE
  99 ....HDELKQLINNAVDENALmkqk.INEEEETEVIAQEAEEILQDEN..AQ.....VEIVKKSL
 100 d...LLREVSEIAVIAGSIINFAES.KIQGRVTVMNGIDEELDEIRDT..YE.....NMPMVLTA
 101 d...LLREVSEIAVIAGSIINFAES.KIQGRVTVMNGIDEELDEIRDT..YE.....NMPMVLTA
 102 ....RFGIILEKIKTVINDDARym7lnMRTQKCYAVRSNINEFLDIAR..RT.....YTEIVDDI
 103 f...SDDLHHIASLIGKVVDFEG-S.LAENRFTVLPNIDPEIDEKKRR..LM.....GLPSFLTE
 104 ....RFGIILEKIKTVINDDARym7lnMRTQKCYAVRSNINEFLDIAR..RT.....YTEIVDDI
 105 f...SDDLHHIASLIGKVVDFEG-S.LAENRFTVLPNIDPEIDEKKRR..LM.....GLPSFLTE
 106 f...SDDLHHIASLIGKVVDFEG-S.LAENRFTVLPNIDPEIDEKKRR..LM.....GLPSFLTE
 107 ....NDAIMEIEKLINSCINEDCVwa7iqLLNQRSYAVKSDSNGLLDV..SR.....QIYKEVKE
 108 ....NDAIMEIEKLINSCINEDCVwa7iqLLNQRSYAVKSDSNGLLDV..SR.....QIYKEVKE
 109 ....RQTPIsk9sdLLREVSEIAVI.AGSIINFAESKIQGRVTVMNGI..DE.....ELDEIRDT
 110 ....LKSLIKEIERIFQVDSLLGDF.KDVIQPIGNLPNLFEQRQTLR-..--.....AQLTEWAE
 111 ....Mk13lkDPRFDQIMNILVEKV.DDSLLdg8lhLQNTKCYAIRHF..VA.....VQLDLARQ
 112 ....RDAFDWSD-ADRNGRFIPYEG.CDPEFDATCNAIEEIKSSLKEY..LK.....EQRKLLRP
 113 ....---------------------.----------------------..--.....--------
 114 ....NPPAVIRDGGVLKAGYDNELD.EMLAISENAGQFLIDLEAREKA..RT.....GLANLKVG
 115 ....---------------------.----------------------..--.....--------
 116 d...ISALKECLRKVETVIDFDT-S.RDTKTLTINTGVDNRLDECRNI..YN.....HLEGILLD
 117 ....Lg16vdISALKECLRKVETVI.DFDT-SRDTKTLTINTGVDNRL..DE.....CRNIYNHL
 118 ....---------------------.----------------------..--.....--------
 119 ....---------------------.----------------------..--.....--------


         450               460            470          480       490   
          |                 |              |            |         |   
   1 VFGYYLEVTRPYY....ER....VPKE.....YRPVQTLKD...RQRYTLPEMKEKEREVYRLEA
   2 VFGYYLEVTRPYY....ER....VPKE.....YRPVQTLKD...RQRYTLPEMKEKEREVYRLEA
   3 TGLDTLKVGFNAV....HG....YYIQ.....ISRGQSHLA...PINYMRRQTLKNAERYIIPEL
   4 TGLDTLKVGFNAV....HG....YYIQ.....ISRGQSHLA...PINYMRRQTLKNAERYIIPEL
   5 TGLDTLKVGFNAV....HG....YYIQ.....ISRGQSHLA...PINYMRRQTLKNAERYIIPEL
   6 VFGYYLEVTRPYY....EK....VPQE.....YRPVQTLKD...RQRYTLPEMKERERELYRLEA
   7 VFGYYLEVTRPYY....EK....VPQE.....YRPVQTLKD...RQRYTLPEMKERERELYRLEA
   8 TGIDTLKIGFNAV....HG....YYIQ.....ISQGQAHKA...PIHYVRRQTLKNAERYIIPEL
   9 TGLPNLKVGYNRI....HG....YYIE.....LPRVQAEQA...PADYIRRQTLKGAERFITPEL
  10 TGLPNLKVGYNRI....HG....YFIE.....LPRVQAEQA...PADYIRRQTLKGAERFITPEL
  11 TGLPNLKVGYNRI....HG....YFIE.....LPRVQAEQA...PADYIRRQTLKGAERFITPEL
  12 HGIDTLKVGYNNV....HG....FYIQ.....VSRGQSHLV...PPHYVRRQTLKNAERYIIEEL
  13 VFGYYLEVTRPYY....EK....VPQE.....YRPVQTLKD...RQRYTLPEMKERERELYRLEA
  14 TGLDTLKVGYNAV....HG....YYIQ.....ISRGQSHLA...PINYVRRQTLKNAERYIIPEL
  15 VFGYYLEVTRPYY....EK....VPQE.....YRPVQTLKD...RQRYTLPEMKERERELYRLEA
  16 QKLRVGYNQVFGY....YI....EVTK.....ANLDKIPDD...YERKQTLVNSERFITPELKEF
  17 KMQSTLISAARDL....GL....Dpgk.....QIKLDSSAQ...FGYYFRVTCKEEKVLRNNknF
  18 KMQSTLISAARDL....GL....Dpgk.....QIKLDSSAQ...FGYYFRVTCKEEKVLRNNknF
  19 KMQSTLISAARDL....GL....Dpgk.....QIKLDSSAQ...FGYYFRVTCKEEKVLRNNknF
  20 QKLRVGYNQVFGY....YI....EVTK.....ANLDKIPDD...YERKQTLVNSERFITPELKEF
  21 KTGIANLKVGYNK....AF....GYYL.....SLPRSKSEQ...APDNYIRKQTLVNEERYITPE
  22 KTGIANLKVGYNK....AF....GYYL.....SLPRSKSEQ...APDNYIRKQTLVNEERYITPE
  23 KMQSTLINAARGL....GL....Dpgk.....QIKLDSSAQ...FGYYFRVTCKEEKVLRNNknF
  24 KMQSTLINAARGL....GL....Dpgk.....QIKLDSSAQ...FGYYFRVTCKEEKVLRNNknF
  25 SDYDQALADIREN....EQ....SLLE.....YLEKQRNRI...GCRTIVYWGIGRNRYQLEIPE
  26 SDYDQALADIREN....EQ....SLLE.....YLEKQRNRI...GCRTIVYWGIGRNRYQLEIPE
  27 SDYDQALADIREN....EQ....SLLE.....YLEKQRNRI...GCRTIVYWGIGRNRYQLEIPE
  28 SDYDQALADIREN....EQ....SLLE.....YLEKQRNRI...GCRTIVYWGIGRNRYQLEIPE
  29 TGLDTLKVGYNAV....HG....YYIQ.....ISRGQSHLA...PINYVRRQTLKNAERYIIPEL
  30 SDYDQALADIREN....EQ....SLLE.....YLDKQRSRL...GCKSIVYWGIGRNRYQLEIPE
  31 KMQSTLISAARGL....GL....Dpgk.....QIKLDSSAQ...FGYYFRVTCKEEKVLRNNknF
  32 SDYDQALADIREN....EQ....SLLE.....YLEKQRNRI...GCRTIVYWGIGRNRYQLEIPE
  33 SDYDQALADIREN....EQ....SLLE.....YLDKQRSRL...GCKSIVYWGIGRNRYQLEIPE
  34 YNKKDGYYFHVTN....SQ....LGNV.....PAHFFRKAT...LKNSERFGTEELARIEGDMLE
  35 ETGIKKLKVCYAQ....AL....GYYI.....EVASNLAPQ...LPKEFIRRQSRLHAERFTTQE
  36 TGLSTLKVEFNRV....HG....FYIE.....LSKTQAEQA...PADYQRRQTLKNAERFITPEL
  37 FNKVFGYYIEVTK....AN....LHLL.....EEGrYERNE...TLTNAERYITPELKEKEALIL
  38 TGLSTLKVEFNRV....HG....FYIE.....LSKTQAEQA...PADYQRRQTLKNAERFITPEL
  39 SGISTLKVGYNRV....HG....YYIE.....ISKGQADKA...PVHYTRRQTLTNAERYITEEL
  40 ETGIKKLKICFAQ....AL....GYYI.....EVSSEFAPQ...LPKDFIRRQSRLHAERFTTIE
  41 kNEIQEVIHSIQM....RL....QEFR.....KILKLPSLQ...YVTVSGQEFMIEIKNSAVSCI
  42 kNEIQEVIHSIQM....RL....QEFR.....KILKLPSLQ...YVTVSGQEFMIEIKNSAVSCI
  43 kNEIQEVIHSIQM....RL....QEFR.....KILKLPSLQ...YVTVSGQEFMIEIKNSAVSCI
  44 TGIQSLKIGYNKV....MG....YYIE.....VTKANVKYV...PEHFRRRQTLSNAERYTTEEL
  45 FNKVFGYYIEVTK....AN....LHLL.....EEGrYERNE...TLTNAERYITPELKEKEALIL
  46 ETGIKKLKICFAQ....AL....GYYI.....EVSSEFAPQ...LPKDFIRRQSRLHAERFTTIE
  47 ETGIKKLKVCYAQ....AL....GYYI.....EVASSFAPQ...LPKEFIRRQSRLHAERFTTQE
  48 NMQGALGGAAREL....GL....Dagk.....SIKLESNSQ...IGHYFRVTCKEEKALRNNkkF
  49 TGIQSLKIGYNKV....MG....YYIE.....VTKPNLKYV...PSYFRRRQTLSNSERFTTEEL
  50 QELEDELMEILMT....YR....KQFK.....CSNIQYKDS...GKEIYTIEIPISATKNVPSNW
  51 QELEDELMEILMT....YR....KQFK.....CSNIQYKDS...GKEIYTIEIPISATKNVPSNW
  52 KMQSTLISAARDL....GL....Dpgk.....QIKLDSSAQ...FGYYFRVTCKE----------
  53 kNEIQEVIHSIQM....RL....QEFR.....KILKLPSLQ...YVTVSGQEFMIEIKNSAVSCI
  54 QYRKETRIESLKI....SH....NNVL.....GFFIDITPK...NVNKiLDPKFIHRQTTINSVR
  55 YQSELKNELYALL....EQ....YKKQ.....LRCSSLNFK...NIGKEVYQVEVPSDV--KVPV
  56 RTGIGTLKMKYNR....ML....GHFL.....EVSKGHLSA...VPAHFIRRRSLSNADRFTTEQ
  57 ADEEYDCACKTVE....EF....ESSL.....KKHLKEQRK...LLGDASINYVTVGKDEYLLEV
  58 TGIKSLKIKHNNV....LG....YFIE.....VTAGNAGSM...TDTda6arFIHRQTMANAMRF
  59 RVIPHEGADEEYD....CA....CKTV.....EEFESSLKK...HLKEQRKLLGDASINYVTVGK
  60 KKRkDEIQGVIDE....IR....MHLQ.....EIRKILKNP...SAQYVTVSGQEFMIEIKNSAV
  61 -------------....--....----.....---------...---------------------
  62 IELDLQvdkALKL....DK....AAQF.....GHVFRITKK...EEPKIRKKlttqFIVLETRKD
  63 KKRkDEIQGVIDE....IR....MHLQ.....EIRKILKNP...SAQYVTVSGQEFMIEIKNSAV
  64 KINNLKIRKTNNR....GL....FFEV.....TKSNYAQVP...PHFMESQALNSSKRYKTEKLI
  65 GCDEEYDEALNRV....KE....ALNE.....LNDYKDSVA...KKYSCS-IKFVDSGKVKYLLE
  66 -------------....--....----.....---------...---------------------
  67 KMEELQFKCSQEL....NL....Dgkn.....QVKLESVAK...LGHHFRITVKDDSVLRKNknY
  68 FAEAAEDLGQErek...KI....FLEN.....HKVHGWCMR...LTRTEAGCIRNNsrYLECSTQ
  69 KMEELQFKCSQEL....NL....Dgkn.....QVKLESVAK...LGHHFRITVKDDSVLRKNknY
  70 RELKMSILMVRTE....MD....FHLQ.....ELRDYLEYP...NLEFSIWGNVKFCIEVSKGC-
  71 RELKMSILMVRTE....MD....FHLQ.....ELRDYLEYP...NLEFSIWGNVKFCIEVSKGC-
  72 AEYDAAMDSIGEV....EK....RLKT.....YLVEQERHF...GCR-ITYFGSDKKRYQLDVPE
  73 EGIIKIQRESESV....RS....QLKE.....ELAEIRKYL...KRPYLNFR--DEVDYLIEVKN
  74 QFPELAEARQAVL....VI....REKL.....DSSIASFRK...KLAIRNLEFLQVSGITHLIEL
  75 IELDLQvdkALKL....DK....AAQF.....GHVFRITKK...EEPKIRKKlttqFIVLETRKD
  76 EGIIKIQRESESV....RS....QLKE.....ELAEIRKYL...KRPYLNFR--DEVDYLIEVKN
  77 LGKIRSKLDTLRD....EI....HSIH.....LDSAEDLGF...DpdkKLKLENHHLHGWCMRLT
  78 LGKIRSKLDTLRD....EI....HSIH.....LDSAEDLGF...DpdkKLKLENHHLHGWCMRLT
  79 -------------....--....----.....---------...---------------------
  80 SSEFDIRQSFKEN....--....----.....---------...------------WVVKSNFNN
  81 -------------....--....----.....---------...---------------------
  82 QFKCSQELNLDgkn...QV....KLES.....VAKLGHHFR...ITVKDDSVLRKNknYRIVDVI
  83 SDLDLSvdkQLKL....EK....-GSL.....GHVFRMSKK...EEQKVRKKltgsYLIIETRKD
  84 -------------....--....----.....---------...---------------------
  85 DLRQRLDELQHSI....FE....EHKR.....VGSDLHQDtek.KLHLEQHHLYGWCLRLTRTEA
  86 DLRQRLDELQHSI....FE....EHKR.....VGSDLHQDtek.KLHLEQHHLYGWCLRLTRTEA
  87 TSSDQFPELAEAR....QA....VLVI.....REKLDSSIA...SFRKKLAIRNLEFLQVSGITH
  88 -LYKIVDIPSLSY....--....----.....---------...---------------------
  89 -LYKIVDIPSLSY....--....----.....---------...---------------------
  90 TSSDQFPELAEAR....QA....VLVI.....REKLDSSIA...SFRKKLAIRNLEFLQVSGITH
  91 KESNKDEIFEL--....--....----.....---------...---------------------
  92 -------------....--....----.....---------...---------------------
  93 KESNKDEIFEL--....--....----.....---------...---------------------
  94 ERVAEKLRKKYSA....KF....ECDN.....LKLDKNSQY...GFYFRVTLKEEKSIRKKdvHI
  95 VVKAIESEHQRVM....KV....YGWTek...QLKCEYHTT...YGYVFRVTRKEDQQVRTSkeL
  96 -------------....--....----.....---------...---------------------
  97 VAQKELENLDsrI....PS....CSVI.....YIPLIGFLL...SIPR-----------------
  98 VAQKELENLDsrI....PS....CSVI.....YIPLIGFLL...SIPR-----------------
  99 SSEFDIRQSFKEN....--....----.....---------...------------WVVKSNFNN
 100 IAKQEEARLGLPpys..NV....ACVY.....IPLVGFVLS...VPRDY----------------
 101 IAKQEEARLGLPpys..NV....ACVY.....IPLVGFVLS...VPRDY----------------
 102 AGMISQLGEKYSL....P-....LRTS.....FSSARGFFI...QMTTDCIalpsDQLPSEFIKI
 103 VARKELENLDsrI....PS....CSVI.....YIPLIGFLL...SIPR-----------------
 104 AGMISQLGEKYSL....P-....LRTS.....LSSVRGFFI...QMTTDCIalpsDQLPSEFIKI
 105 VARKELENLDsrI....PS....CSVI.....YIPLIGFLL...SIPR-----------------
 106 VARKELENLDsrI....PS....CSVI.....YIPLIGFLL...SIPR-----------------
 107 EFFREVEDLTAKN....KI....N-LD.....HNYDSARGF...YLRIKRQEFTDdvatLPDVFI
 108 EFFREVEDLTAKN....KI....N-LD.....HNYDSARGF...YLRIKRQEFTDdvatLPDVFI
 109 YENMPMVLTAIAK....QE....EARL.....GLPpysNVA...CVYIPLVGFVLSVPRDY----
 110 QISNIVFQDttSI....KA....EYFN.....KEGYAFSIS...SKKLTKLEHYMMNTSISNN--
 111 TYEEIIRNVEETG....AR....EIAE.....YFHGnsSVR...LSFSQSRGFHYTFVTRQAESv
 112 ASVNYVNVGKDMY....LI....EVPE.....SLGGSVPRN...YELQSTKKGFYRYWTPELKEL
 113 -------------....--....----.....---------...---------------------
 114 YNRVHGYFIELPT....KQ....AEQA.....PGDYIRRQT...LKGAERFITPELKAFEDKALS
 115 -------------....--....----.....---------...---------------------
 116 VARETQIFLLNTm....14ek..LVNA.....VYIPQLGYL...VTISVLMEPLldgIPNLqWEE
 117 EGILLDVARETQI....FL....LNTm.....14ekLVNAV...YIPQLGYLVTISVLMEPLldg
 118 -------------....--....----.....---------...---------------------
 119 -------------....--....----.....---------...---------------------


          500
           |
   1 LIRRREE
   2 LIRRREE
   3 KEYEDKV
   4 KEYEDKV
   5 KEYEDKV
   6 LIKRREE
   7 LIKRREE
   8 KEYEDKV
   9 KAFEDKA
  10 KAFEDKA
  11 KAFEDKA
  12 KQHEDKV
  13 LIKRREE
  14 KEYEDKV
  15 LIKRREE
  16 ETKIMAA
  17 STVDIQK
  18 STVDIQK
  19 STVDIQK
  20 ETKIMAA
  21 LKERETR
  22 LKERETR
  23 STVDIQK
  24 STVDIQK
  25 NFTTRnL
  26 NFTTRnL
  27 NFTTRnL
  28 NFTTRnL
  29 KEYEDKV
  30 NFATRnL
  31 STVDIQK
  32 NFTTRnL
  33 NFATRnL
  34 AREKSAN
  35 LQQFQDE
  36 KAFEDKV
  37 EAENNIC
  38 KAFEDKV
  39 KAFEDKV
  40 LQQFQDD
  41 PADWVKV
  42 PADWVKV
  43 PADWVKV
  44 QRLEEKI
  45 EAENNIC
  46 LQQFQDD
  47 LQQFQDE
  48 TTIDIQK
  49 QRLEEKI
  50 VQMAANK
  51 VQMAANK
  52 -------
  53 PADWVKV
  54 YTTYELQ
  55 NWCKMSG
  56 LSELEAK
  57 PESLSGS
  58 TTTELAE
  59 DEYLLEV
  60 SCIPTDW
  61 -------
  62 GVKFTNT
  63 SCIPTDW
  64 SLEVDIN
  65 MPEN--T
  66 -------
  67 RIVDVIK
  68 KNGVYFT
  69 RIVDVIK
  70 KKIPPDW
  71 KKIPPDW
  72 SHASKAN
  73 SQIKDLP
  74 PVD--SK
  75 GVKFTNT
  76 SQIKDLP
  77 RNDAKEL
  78 RNDAKEL
  79 -------
  80 NLRKLHE
  81 -------
  82 KGGVRFT
  83 GVKFTNS
  84 -------
  85 GCLRGRs
  86 GCLRGRs
  87 LIELPVD
  88 -------
  89 -------
  90 LIELPVD
  91 -------
  92 -------
  93 -------
  94 LETTKGS
  95 ITVSTSK
  96 -------
  97 -------
  98 -------
  99 NLRKLHE
 100 -------
 101 -------
 102 SKVKNSY
 103 -------
 104 SKVKNSY
 105 -------
 106 -------
 107 SRTIKKN
 108 SRTIKKN
 109 -------
 110 -------
 111 tIPRYFL
 112 ILELSKA
 113 -------
 114 AKSRALA
 115 -------
 116 IFRSSEN
 117 IPNLqWE
 118 -------
 119 -------