a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1999.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0115-outer Homoserine kinase, Methanococcus jannaschii
- gi|140422|sp|P24209|IPK_ECOLI_7:190 ISOPENTENYL MONOPHOSPHATE KINASE (4-(CYTIDINE-5'-DIPHOSPHO)-2-C-METHYL-D-ERYTHRITOL KINASE) (Escherichia coli)
- gi|477736|pir||B47706 ychB protein - Escherichia coli (Escherichia coli)
- gi|147382|gb|AAA24434.1| (M77237) ORF2 [Escherichia coli] (Escherichia coli)
- gi|968927|gb|AAC43434.1| (U18555) orfY gene product [Escherichia coli] (Escherichia coli)
- gi|1787459|gb|AAC74292.1| (AE000219) orf, hypothetical protein [Escherichia coli] (Escherichia coli)
- gi|4062791|dbj|BAA36066.1| (D90756) 31k hypothetical protein (5' of prs) [Escherichia coli] (Escherichia coli)
- gi|6478466|gb|AAF13867.1| (AF179284) isopentenyl monophosphate kinase [Escherichia coli] (Escherichia coli)
- gi|6687497|emb|CAB64963.1| (AJ249325) isopentenyl monophosphate kinase [Escherichia coli] (Escherichia coli)
- gi|6851369|gb|AAF29530.1|AF216300_1 (AF216300) 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Escherichia coli] (Escherichia coli)
- gi|7527350|dbj|BAA94247.1| (AB037116) 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythrito l kinase [Escherichia coli] (Escherichia coli)
- gi|549526|sp|P30753|IPK_SALTY_7:190 ISOPENTENYL MONOPHOSPHATE KINASE (Salmonella typhimurium)
- gi|282005|pir||S27732 conserved hypothetical protein 2 - Salmonella typhimurium (Salmonella typhimurium)
- gi|154282|gb|AAA27195.1| (M77236) ORF2 [Salmonella typhimurium] (Salmonella typhimurium)
- gi|1175665|sp|P42805|IPK_PSEAE_9:186 ISOPENTENYL MONOPHOSPHATE KINASE (Pseudomonas aeruginosa)
- gi|1072996|pir||S49374 conserved hypothetical protein 2 - Pseudomonas aeruginosa (fragment) (Pseudomonas aeruginosa)
- gi|557257|emb|CAA57570.1| (X82071) orf2 [Pseudomonas aeruginosa] (Pseudomonas aeruginosa)
- gi|1074864|pir||A64173_34:212 conserved hypothetical protein HI1608 - Haemophilus influenzae (strain Rd KW20) (Haemophilus influenzae)
- gi|9950924|gb|AAG08056.1|AE004880_12_9:186 (AE004880) isopentenyl monophosphate kinase [Pseudomonas aeruginosa] (Pseudomonas aeruginosa)
- gi|1175664|sp|P45271|IPK_HAEIN_26:204 ISOPENTENYL MONOPHOSPHATE KINASE (Haemophilus influenzae)
- gi|1574450|gb|AAC23252.1| (U32834) conserved hypothetical protein [Haemophilus influenzae Rd] (Haemophilus influenzae Rd)
- gi|6831546|sp|O85253|GAL1_THENE_1:191 GALACTOKINASE (Thermotoga neapolitana)
- gi|3252901|gb|AAC24222.1| (AF055482) galactose kinase [Thermotoga neapolitana] (Thermotoga neapolitana)
- gi|2494673|sp|P96993|GAL1_STRMU_21:219 GALACTOKINASE (Streptococcus mutans)
- gi|7434205|pir||JC5311 galactokinase (EC 2.7.1.6) - Streptococcus mutans (Streptococcus mutans)
- gi|1877422|gb|AAB49736.1| (U21942) galactokinase [Streptococcus mutans] (Streptococcus mutans)
- gi|6831547|sp|P56838|GAL1_THEMA_1:191 GALACTOKINASE (Thermotoga maritima)
- gi|7434204|pir||C72283 galactokinase - Thermotoga maritima (strain MSB8) (Thermotoga maritima)
- gi|4981741|gb|AAD36265.1|AE001776_1 (AE001776) galactokinase [Thermotoga maritima] (Thermotoga maritima)
- gi|6648061|sp|P04948|KHSE_BACSU_8:240 HOMOSERINE KINASE (HK) (Bacillus subtilis)
- gi|7450505|pir||H69722 homoserine kinase (EC 2.7.1.39) - Bacillus subtilis (Bacillus subtilis)
- gi|2635721|emb|CAB15214.1| (Z99120) homoserine kinase [Bacillus subtilis] (Bacillus subtilis)
- gi|7379787|emb|CAB84355.1|_12:189 (AL162755) hypothetical protein NMA1092 [Neisseria meningitidis] (Neisseria meningitidis)
- gi|4206187|gb|AAD11510.1|_30:228 (U60828) galactokinase [Lactococcus lactis] (Lactococcus lactis)
- gi|80285|pir||B25364_8:239 homoserine kinase (EC 2.7.1.39) - Bacillus subtilis (Bacillus subtilis)
- gi|40212|emb|CAA28271.1| (X04603) homoserine kinase [Bacillus subtilis] (Bacillus subtilis)
- gi|4995690|emb|CAB44216.1|_30:228 (AJ011653) galactokinase [Lactococcus lactis] (Lactococcus lactis)
- gi|147980|gb|AAA83915.1|_3:241 (J01706) homoserine kinase [Escherichia coli] (Escherichia coli)
- gi|216436|dbj|BAA01287.1| (D10483) homoserine kinase [Escherichia coli] (Escherichia coli)
- gi|7226111|gb|AAF41285.1|_12:189 (AE002439) conserved hypothetical protein [Neisseria meningitidis MC58] (Neisseria meningitidis MC58)
- gi|266419|sp|P00547|KHSE_ECOLI_3:242 HOMOSERINE KINASE (HK) (Escherichia coli)
- gi|1361027|pir||S56630 homoserine kinase (EC 2.7.1.39) thrB - Escherichia coli (Escherichia coli)
- gi|7428038|pir||KIECM homoserine kinase (EC 2.7.1.39) - Escherichia coli (Escherichia coli)
- gi|529240|gb|AAA20618.1| (L13601) homoserine kinase [Escherichia coli] (Escherichia coli)
- gi|537246|gb|AAA97302.1| (U14003) homoserine kinase [Escherichia coli] (Escherichia coli)
- gi|1786184|gb|AAC73114.1| (AE000111) homoserine kinase [Escherichia coli] (Escherichia coli)
- gi|6967628|emb|CAB72618.1|_1:233 (AL139074) homoserine kinase [Campylobacter jejuni] (Campylobacter jejuni)
- gi|6321814|ref|NP_011890.1|_5:290 homoserine kinase; Thr1p (Saccharomyces cerevisiae)
- gi|125396|sp|P17423|KHSE_YEAST HOMOSERINE KINASE (HK) (Saccharomyces cerevisiae)
- gi|630045|pir||S46772 homoserine kinase (EC 2.7.1.39) - yeast (Saccharomyces cerevisiae) (Saccharomyces cerevisiae)
- gi|172978|gb|AAA35154.1| (M37692) homoserine kinase [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|500690|gb|AAB68871.1| (U10399) Thr1p: Homoserine kinase [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|125395|sp|P27722|KHSE_SERMA_3:242 HOMOSERINE KINASE (HK) (Serratia marcescens)
- gi|421255|pir||C47057 homoserine kinase (EC 2.7.1.39) - Serratia marcescens (Serratia marcescens)
- gi|47274|emb|CAA43213.1| (X60821) homoserine kinase [Serratia marcescens] (Serratia marcescens)
- gi|216967|dbj|BAA38482.1| (D10387) homoserine kinase [Serratia marcescens] (Serratia marcescens)
- gi|125393|sp|P04947|KHSE_FREDI_4:241 HOMOSERINE KINASE (HK) (Fremyella diplosiphon)
- gi|79795|pir||S03743 homoserine kinase (EC 2.7.1.39) - Calothrix sp (Calothrix sp.)
- gi|43396|emb|CAA68576.1| (Y00522) homoserine kinase (AA 1-307) [Calothrix PCC7601] (Calothrix PCC7601)
- gi|6707009|gb|AAF25548.1|AF109295_3_21:218 (AF109295) GalK [Staphylococcus carnosus] (Staphylococcus carnosus)
- gi|7472024|pir||G75280_7:240 homoserine kinase - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6460205|gb|AAF11935.1|AE002069_9 (AE002069) homoserine kinase [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|9656736|gb|AAF95327.1|_15:192 (AE004289) kinase, GHMP family [Vibrio cholerae] (Vibrio cholerae)
- gi|729557|sp|P39574|GAL1_BACSU_21:219 GALACTOKINASE (Bacillus subtilis)
- gi|629042|pir||S39690 galactokinase (EC 2.7.1.6) galK - Bacillus subtilis (Bacillus subtilis)
- gi|413959|emb|CAA51591.1| (X73124) ipa-35d galK [Bacillus subtilis] (Bacillus subtilis)
- gi|2636355|emb|CAB15846.1| (Z99123) galactokinase [Bacillus subtilis] (Bacillus subtilis)
- gi|4614|emb|CAA37083.1|_5:289 (X52901) homoserine kinase (AA 1-356) [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|6225403|sp|O84902|GAL1_LACCA_21:218 GALACTOKINASE (Lactobacillus casei)
- gi|3201656|gb|AAC19328.1| (AF005933) galactokinase [Lactobacillus casei] (Lactobacillus casei)
- gi|7450509|pir||B64651_3:230 homoserine kinase - Helicobacter pylori (strain 26695) (Helicobacter pylori)
- gi|2314197|gb|AAD08095.1| (AE000612) homoserine kinase (thrB) [Helicobacter pylori 26695] (Helicobacter pylori 26695)
- gi|120900|sp|Q00052|GAL1_LACHE_22:219 GALACTOKINASE (Lactobacillus helveticus)
- gi|421585|pir||A47032 galactokinase galK - Lactobacillus helveticus (Lactobacillus helveticus)
- gi|44000|emb|CAA40525.1| (X57248) galactokinase [Lactobacillus helveticus] (Lactobacillus helveticus)
- gi|9107876|gb|AAF85442.1|AE004071_10_22:200 (AE004071) isopentenyl monophosphate kinase [Xylella fastidiosa] (Xylella fastidiosa)
- gi|7450510|pir||C71940_3:230 homoserine kinase - Helicobacter pylori (strain J99) (Helicobacter pylori)
- gi|4154901|gb|AAD05950.1| (AE001472) HOMOSERINE KINASE [Helicobacter pylori J99] (Helicobacter pylori J99)
- gi|5733507|gb|AAD49612.1|_23:220 (AF152357) galactokinase GalK [Streptococcus thermophilus] (Streptococcus thermophilus)
- gi|2497515|sp|Q58504|KHSE_METJA_3:296 HOMOSERINE KINASE (HK) (Methanococcus jannaschii)
- gi|2127974|pir||G64437 homoserine kinase (EC 2.7.1.39) - Methanococcus jannaschii (Methanococcus jannaschii)
- gi|1591748|gb|AAB99107.1| (U67553) homoserine kinase (thrB) [Methanococcus jannaschii] (Methanococcus jannaschii)
- gi|120898|sp|P06976|GAL1_ECOLI_21:180 GALACTOKINASE (Escherichia coli)
- gi|66661|pir||KIECGG galactokinase (EC 2.7.1.6) - Escherichia coli (Escherichia coli)
- gi|41532|emb|CAA26172.1| (X02306) galaktokinase [Escherichia coli] (Escherichia coli)
- gi|58030|emb|CAA47408.1| (X67018) galK [synthetic construct] (synthetic construct)
- gi|58033|emb|CAA47410.1| (X67019) galK gene from E.coli [synthetic construct] (synthetic construct)
- gi|595700|gb|AAA57082.1| (U13847) galactokinase [unidentified cloning vector] (unidentified cloning vector)
- gi|1651342|dbj|BAA35419.1| (D90714) Galactokinase (EC 2.7.1.6). [Escherichia coli] (Escherichia coli)
- gi|1786972|gb|AAC73844.1| (AE000178) galactokinase [Escherichia coli] (Escherichia coli)
- gi|208230|gb|AAA72509.1|_21:180 (K03394) galK [unidentified cloning vector] (unidentified cloning vector)
- gi|6225592|sp|O67332|KHSE_AQUAE_3:231 HOMOSERINE KINASE (HK) (Aquifex aeolicus)
- gi|7450507|pir||A70413 homoserine kinase - Aquifex aeolicus (Aquifex aeolicus)
- gi|2983721|gb|AAC07283.1| (AE000733) homoserine kinase [Aquifex aeolicus] (Aquifex aeolicus)
- gi|8928118|sp|Q9ZB10|GALK_STRTR_21:219 GALACTOKINASE (Streptococcus thermophilus)
- gi|4097440|gb|AAD00093.1| (U61402) galactokinase [Streptococcus thermophilus] (Streptococcus thermophilus)
- gi|6919915|sp|P72663|IPK_SYNY3_8:179 ISOPENTENYL MONOPHOSPHATE KINASE (Synechocystis PCC6803)
- gi|7469918|pir||S74513 hypothetical protein sll0711 - Synechocystis sp. (strain PCC 6803) (Synechocystis sp.)
- gi|1651737|dbj|BAA16665.1| (D90899) hypothetical protein [Synechocystis sp.] (Synechocystis sp.)
- gi|7490646|pir||T40495_4:271 homoserine kinase - fission yeast (Schizosaccharomyces pombe) (Schizosaccharomyces pombe)
- gi|2832883|emb|CAA16824.1| (AL021730) homoserine kinase [Schizosaccharomyces pombe] (Schizosaccharomyces pombe)
- gi|9656932|gb|AAF95506.1|_3:248 (AE004306) homoserine kinase [Vibrio cholerae] (Vibrio cholerae)
- gi|2501753|gb|AAC48872.1|_21:180 (U66885) galactokinase [bacteriophage lambda] (bacteriophage lambda)
- gi|2501800|gb|AAC53713.1| (U87107) galactokinase [Cloning vector pAL-F] (Cloning vector pAL-F)
- gi|7532410|gb|AAF63224.1|_49:300 (AC002329) 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|4927412|gb|AAD33097.1|AF082525_1_49:300 (AF082525) homoserine kinase [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|7450508|pir||F72364_1:228 hypothetical protein TM0545 - Thermotoga maritima (strain MSB8) (Thermotoga maritima)
- gi|4981059|gb|AAD35630.1|AE001729_10 (AE001729) homoserine kinase, putative [Thermotoga maritima] (Thermotoga maritima)
- gi|7434441|pir||H75080_4:234 homoserine kinase (EC 2.7.1.39) (hk). PAB1676 - Pyrococcus abyssi (strain Orsay) (Pyrococcus abyssi)
- gi|5458461|emb|CAB49949.1| (AJ248286) HOMOSERINE KINASE (EC 2.7.1.39) (HK). [Pyrococcus abyssi] (Pyrococcus abyssi)
- gi|1170650|sp|P44504|KHSE_HAEIN_3:250 HOMOSERINE KINASE (HK) (Haemophilus influenzae)
- gi|1074209|pir||I64047 homoserine kinase (EC 2.7.1.39) - Haemophilus influenzae (strain Rd KW20) (Haemophilus influenzae)
- gi|1573039|gb|AAC21766.1| (U32694) homoserine kinase (thrB) [Haemophilus influenzae Rd] (Haemophilus influenzae Rd)
- gi|125390|sp|P07128|KHSE_BRELA_9:245 HOMOSERINE KINASE (HK) (Brevibacterium lactofermentum)
- gi|39588|emb|CAA68332.1| (Y00140) homoserine kinase (AA 1-309) [Corynebacterium glutamicum] (Corynebacterium glutamicum)
- gi|2292917|emb|CAA68163.1|_49:215 (X99851) galactokinase [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|2736186|gb|AAB94084.1|_49:215 (AF024623) galactose kinase [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|125391|sp|P08210|KHSE_CORGL_9:245 HOMOSERINE KINASE (HK) (Corynebacterium glutamicum)
- gi|66855|pir||KIFKMG homoserine kinase (EC 2.7.1.39) - Corynebacterium glutamicum (Corynebacterium glutamicum)
- gi|40504|emb|CAA68615.1| (Y00546) homoserine kinase (HK) (AA 1-309) [Corynebacterium glutamicum] (Corynebacterium glutamicum)
- gi|2497514|sp|P73646|KHSE_SYNY3_4:239 HOMOSERINE KINASE (HK) (Synechocystis PCC6803)
- gi|7450506|pir||S77133 homoserine kinase (EC 2.7.1.39) - Synechocystis sp. (strain PCC 6803) (Synechocystis sp.)
- gi|1652772|dbj|BAA17691.1| (D90908) homoserine kinase [Synechocystis sp.] (Synechocystis sp.)
- gi|6537164|gb|AAF15552.1|_49:215 (AF152851) galactokinase GAL1 [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|7543733|gb|AAF63635.1|_49:215 (AC020580) galactose kinase [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|9937364|gb|AAG02424.1|AF290087_1_6:177 (AF290087) mevalonate kinase [Staphylococcus aureus] (Staphylococcus aureus)
- gi|9656105|gb|AAF94749.1|_41:203 (AE004236) galactokinase [Vibrio cholerae] (Vibrio cholerae)
- gi|9937372|gb|AAG02430.1|AF290089_1_5:177 (AF290089) mevalonate kinase [Staphylococcus haemolyticus] (Staphylococcus haemolyticus)
- gi|9107373|gb|AAF85023.1|AE004035_2_16:255 (AE004035) homoserine kinase [Xylella fastidiosa] (Xylella fastidiosa)
- gi|9937379|gb|AAG02435.1|AF290091_1_6:176 (AF290091) mevalonate kinase [Staphylococcus epidermidis] (Staphylococcus epidermidis)
- gi|8928130|sp|O27995|KIME_ARCFU_1:151 MEVALONATE KINASE (MK) (Archaeoglobus fulgidus)
- gi|7483872|pir||A69536 mevalonate kinase (mvk) homolog - Archaeoglobus fulgidus (Archaeoglobus fulgidus)
- gi|2648230|gb|AAB88965.1| (AE000946) mevalonate kinase (mvk) [Archaeoglobus fulgidus] (Archaeoglobus fulgidus)
- gi|2497513|sp|P72535|KHSE_STRPN_1:225 HOMOSERINE KINASE (HK) (Streptococcus pneumoniae)
- gi|1498295|gb|AAC44297.1| (U41735) homoserine kinase homolog [Streptococcus pneumoniae] (Streptococcus pneumoniae)
- gi|8928178|sp|O59291|KIME_PYRHO_6:186 MEVALONATE KINASE (MK) (Pyrococcus horikoshii)
- gi|7521211|pir||A71042 probable mevalonate kinase - Pyrococcus horikoshii (Pyrococcus horikoshii)
- gi|3258054|dbj|BAA30737.1| (AP000006) 335aa long hypothetical mevalonate kinase [Pyrococcus horikoshii] (Pyrococcus horikoshii)
- gi|586879|sp|P37550|IPK_BACSU_7:171 ISOPENTENYL MONOPHOSPHATE KINASE (Bacillus subtilis)
- gi|2127037|pir||S66075 conserved hypothetical protein yabH - Bacillus subtilis (Bacillus subtilis)
- gi|467435|dbj|BAA05281.1| (D26185) unknown [Bacillus subtilis] (Bacillus subtilis)
- gi|2632313|emb|CAB11822.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis] (Bacillus subtilis)
- gi|1730045|sp|P52991|KHSE_LACLA_1:231 HOMOSERINE KINASE (HK) (Lactococcus lactis subsp. lactis)
- gi|2126613|pir||JC6050 homoserine kinase (EC 2.7.1.39) - Lactococcus lactis (Lactococcus lactis)
- gi|1255940|emb|CAA65714.1| (X96988) thrB [Lactococcus lactis] (Lactococcus lactis)
- gi|9937395|gb|AAG02447.1|AF290095_3_4:203 (AF290095) phosphomevalonate kinase [Enterococcus faecium] (Enterococcus faecium)
- gi|2497517|sp|Q58487|KIME_METJA_1:176 MEVALONATE KINASE (MK) (Methanococcus jannaschii)
- gi|2129120|pir||F64435 mevalonate kinase (EC 2.7.1.36) - Methanococcus jannaschii (Methanococcus jannaschii)
- gi|1591731|gb|AAB99088.1| (U67551) mevalonate kinase [Methanococcus jannaschii] (Methanococcus jannaschii)
- gi|9937388|gb|AAG02442.1|AF290093_3_4:203 (AF290093) phosphomevalonate kinase [Enterococcus faecalis] (Enterococcus faecalis)
- gi|2497516|sp|Q92209|KHSE_CANAL_5:142 HOMOSERINE KINASE (HK) (Candida albicans)
- gi|1546063|gb|AAB08101.1| (U67193) homoserine kinase [Candida albicans] (Candida albicans)
- gi|7521143|pir||E72511_33:280 probable homoserine kinase APE2067 - Aeropyrum pernix (strain K1) (Aeropyrum pernix)
- gi|5105765|dbj|BAA81077.1| (AP000063) 343aa long hypothetical homoserine kinase [Aeropyrum pernix] (Aeropyrum pernix)
- gi|6919916|sp|Q9X1A3|IPK_THEMA_14:161 ISOPENTENYL MONOPHOSPHATE KINASE (Thermotoga maritima)
- gi|7462336|pir||H72261 conserved hypothetical protein - Thermotoga maritima (strain MSB8) (Thermotoga maritima)
- gi|4981944|gb|AAD36453.1|AE001791_15 (AE001791) conserved hypothetical protein [Thermotoga maritima] (Thermotoga maritima)
- gi|9937380|gb|AAG02436.1|AF290091_2_18:156 (AF290091) mevalonate diphosphate decarboxylase [Staphylococcus epidermidis] (Staphylococcus epidermidis)
- gi|8928195|sp|Q9V187|KIME_PYRAB_6:185 MEVALONATE KINASE (MK) (Pyrococcus abyssi)
- gi|7519971|pir||H75172 mevalonate kinase (mvk) PAB0372 - Pyrococcus abyssi (strain Orsay) (Pyrococcus abyssi)
- gi|5457973|emb|CAB49463.1| (AJ248284) mevalonate kinase (mvk) [Pyrococcus abyssi] (Pyrococcus abyssi)
- gi|3913721|sp|P56599|GAL1_CANMA_40:207 GALACTOKINASE (Candida maltosa)
- gi|2660644|emb|CAA04516.1|_1:127 (AJ001072) galactokinase [Thermotoga maritima] (Thermotoga maritima)
- gi|6919911|sp|O67060|IPK_AQUAE_6:155 ISOPENTENYL MONOPHOSPHATE KINASE (Aquifex aeolicus)
- gi|7450511|pir||A70379 conserved hypothetical protein aq_915 - Aquifex aeolicus (Aquifex aeolicus)
- gi|2983445|gb|AAC07027.1| (AE000713) hypothetical protein [Aquifex aeolicus] (Aquifex aeolicus)
- gi|6016092|sp|O42821|GAL1_CANPA_40:219 GALACTOKINASE (Candida parapsilosis)
- gi|2959759|emb|CAA75006.1| (Y14704) galactokinase [Candida parapsilosis] (Candida parapsilosis)
- gi|9937365|gb|AAG02425.1|AF290087_2_18:157 (AF290087) mevalonate diphosphate decarboxylase [Staphylococcus aureus] (Staphylococcus aureus)
- gi|9937381|gb|AAG02437.1|AF290091_3_3:206 (AF290091) phosphomevalonate kinase [Staphylococcus epidermidis] (Staphylococcus epidermidis)
- gi|2494674|sp|P56091|GAL1_CANAL_41:223 GALACTOKINASE (Candida albicans)
- gi|2245669|gb|AAB62568.1| (AF006591) galactokinase [Candida albicans] (Candida albicans)
- gi|7471511|pir||E75254_14:166 conserved hypothetical protein - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6460432|gb|AAF12142.1|AE002089_5 (AE002089) conserved hypothetical protein [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|321817|pir||PC1178_3:131 hypothetical 21.8K protein (hemM 3' region) - Escherichia coli (Escherichia coli)
- gi|912433|dbj|BAA01106.1| (D10264) ORF3 [Escherichia coli] (Escherichia coli)
- gi|9937394|gb|AAG02446.1|AF290095_2_17:184 (AF290095) mevalonate diphosphate decarboxylase [Enterococcus faecium] (Enterococcus faecium)
- gi|6919909|sp|O05596|IPK_MYCTU_10:160 ISOPENTENYL MONOPHOSPHATE KINASE (Mycobacterium tuberculosis)
- gi|7476599|pir||F70603 hypothetical protein Rv1011 - Mycobacterium tuberculosis (strain H37RV) (Mycobacterium tuberculosis)
- gi|2052148|emb|CAB08138.1| (Z94752) hypothetical protein Rv1011 [Mycobacterium tuberculosis] (Mycobacterium tuberculosis)
- gi|7434202|pir||F71144_3:176 probable galactokinase - Pyrococcus horikoshii (Pyrococcus horikoshii)
- gi|3256760|dbj|BAA29443.1| (AP000002) 350aa long hypothetical galactokinase [Pyrococcus horikoshii] (Pyrococcus horikoshii)
- gi|7190224|gb|AAF39061.1|_5:151 (AE002285) kinase, GHMP family [Chlamydia muridarum] (Chlamydia muridarum)
- gi|1170651|sp|P45836|KHSE_MYCLE_14:179 HOMOSERINE KINASE (HK) (Mycobacterium leprae)
- gi|7434440|pir||T09990 homoserine kinase (EC 2.7.1.39) - Mycobacterium leprae (Mycobacterium leprae)
- gi|699339|gb|AAA63100.1| (U15186) homoserine kinase [Mycobacterium leprae] (Mycobacterium leprae)
- gi|9937408|gb|AAG02456.1|AF290099_2_19:173 (AF290099) mevalonate diphosphate decarboxylase [Streptococcus pneumoniae] (Streptococcus pneumoniae)
- gi|8894769|emb|CAB95929.1|_25:179 (AL359989) galactokinase [Streptomyces coelicolor A3(2)] (Streptomyces coelicolor A3(2))
- gi|7450512|pir||D71103_2:212 probable homoserine kinase - Pyrococcus horikoshii (Pyrococcus horikoshii)
- gi|3257503|dbj|BAA30186.1| (AP000004) 271aa long hypothetical homoserine kinase [Pyrococcus horikoshii] (Pyrococcus horikoshii)
- gi|9937393|gb|AAG02445.1|AF290095_1_6:162 (AF290095) mevalonate kinase [Enterococcus faecium] (Enterococcus faecium)
- gi|6919912|sp|O83386|IPK_TREPA_8:173 ISOPENTENYL MONOPHOSPHATE KINASE (Treponema pallidum)
- gi|7514575|pir||B71333 conserved hypothetical protein TP0371 - syphilis spirochete (Treponema pallidum subsp. pallidum)
- gi|3322649|gb|AAC65356.1| (AE001216) conserved hypothetical protein [Treponema pallidum] (Treponema pallidum)
- gi|8894781|emb|CAB95941.1|_7:165 (AL359989) putative isopentenyl monophosphate kinase [Streptomyces coelicolor A3(2)] (Streptomyces coelicolor A3(2))
- gi|9937401|gb|AAG02451.1|AF290097_2_19:172 (AF290097) mevalonate diphosphate decarboxylase [Streptococcus pyogenes] (Streptococcus pyogenes)
- gi|8979328|dbj|BAA99162.1|_5:135 (AP002548) kinase [Chlamydophila pneumoniae] (Chlamydophila pneumoniae)
- gi|6919913|sp|O84810|IPK_CHLTR_5:154 ISOPENTENYL MONOPHOSPHATE KINASE (Chlamydia trachomatis)
- gi|7468948|pir||B71470 probable kinase - Chlamydia trachomatis (serotype D, strain UW3/Cx) (Chlamydia trachomatis)
- gi|3329270|gb|AAC68399.1| (AE001352) Predicted Kinase [Chlamydia trachomatis] (Chlamydia trachomatis)
- gi|9937373|gb|AAG02431.1|AF290089_2_18:155 (AF290089) mevalonate diphosphate decarboxylase [Staphylococcus haemolyticus] (Staphylococcus haemolyticus)
- gi|9695270|dbj|BAB07790.1|_31:204 (AB037666) mevalonate kinase [Streptomyces sp. CL190] (Streptomyces sp. CL190)
- gi|9937386|gb|AAG02440.1|AF290093_1_8:165 (AF290093) mevalonate kinase [Enterococcus faecalis] (Enterococcus faecalis)
- gi|9695271|dbj|BAB07791.1|_35:172 (AB037666) diphosphomevalonate decarboxylase [Streptomyces sp. CL190] (Streptomyces sp. CL190)
- gi|6968538|emb|CAB73359.1|_4:177 (AL139077) hypothetical proteinCj1104 [Campylobacter jejuni] (Campylobacter jejuni)
- gi|7447991|pir||F75161_26:170 homoserine kinase PAB0301 - Pyrococcus abyssi (strain Orsay) (Pyrococcus abyssi)
- gi|5457883|emb|CAB49373.1| (AJ248284) HOMOSERINE KINASE [Pyrococcus abyssi] (Pyrococcus abyssi)
- gi|2128859|pir||G64479_27:178 hypothetical protein MJ1440 - Methanococcus jannaschii (Methanococcus jannaschii)
- gi|1500322|gb|AAB99451.1| (U67585) conserved hypothetical protein [Methanococcus jannaschii] (Methanococcus jannaschii)
- gi|1730046|sp|Q10603|KHSE_MYCTU_17:180 HOMOSERINE KINASE (HK) (Mycobacterium tuberculosis)
- gi|7434439|pir||D70773 probable thrB protein - Mycobacterium tuberculosis (strain H37RV) (Mycobacterium tuberculosis)
- gi|1322420|emb|CAA97729.1| (Z73419) thrB [Mycobacterium tuberculosis] (Mycobacterium tuberculosis)
- gi|3183231|sp|O26918|Y830_METTH_18:144 HYPOTHETICAL PROTEIN MTH830 (Methanobacterium thermoautotrophicum)
- gi|7429726|pir||G69210 conserved hypothetical protein MTH830 - Methanobacterium thermoautotrophicum (strain Delta H) (Methanobacterium thermoautotrophicum)
- gi|2621920|gb|AAB85328.1| (AE000860) conserved protein [Methanobacterium thermoautotrophicum] (Methanobacterium thermoautotrophicum)
- gi|6323864|ref|NP_013935.1|_8:219 mevalonate kinase; Erg12p (Saccharomyces cerevisiae)
- gi|125407|sp|P07277|KIME_YEAST MEVALONATE KINASE (MK) (MVK) (Saccharomyces cerevisiae)
- gi|73086|pir||BVBYR1 mevalonate kinase (EC 2.7.1.36) - yeast (Saccharomyces cerevisiae) (Saccharomyces cerevisiae)
- gi|3684|emb|CAA39359.1| (X55875) mevalonate kinase [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|4287|emb|CAA29487.1| (X06114) ORF1 (put. RAR1 protein) (AA 1-443) [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|854460|emb|CAA89923.1| (Z49809) Rar1p [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|2804172|dbj|BAA24409.1|_8:218 (D78165) mevalonate kinase [Saccharomyces cerevisiae] (Saccharomyces cerevisiae)
- gi|9711346|dbj|BAB07817.1|_21:180 (AB037907) mevalonate kinase [Streptomyces griseolosporeus] (Streptomyces griseolosporeus)
- gi|8928161|sp|Q9Y946|KIME_AERPE_6:169 MEVALONATE KINASE (MK) (Aeropyrum pernix)
- gi|7521212|pir||F72474 probable mevalonate kinase APE2439 - Aeropyrum pernix (strain K1) (Aeropyrum pernix)
- gi|5106143|dbj|BAA81454.1| (AP000064) 324aa long hypothetical mevalonate kinase [Aeropyrum pernix] (Aeropyrum pernix)
- gi|7447990|pir||E69207_28:169 conserved hypothetical protein MTH805 - Methanobacterium thermoautotrophicum (strain Delta H) (Methanobacterium thermoautotrophicum)
- gi|2621895|gb|AAB85305.1| (AE000858) conserved protein (homoserine kinase related) [Methanobacterium thermoautotrophicum] (Methanobacterium thermoautotrophicum)
- gi|1170660|sp|P46086|KIME_ARATH_4:226 MEVALONATE KINASE (MK) (Arabidopsis thaliana)
- gi|541880|pir||S42088 mevalonate kinase (EC 2.7.1.36) - Arabidopsis thaliana (Arabidopsis thaliana)
- gi|456614|emb|CAA54820.1| (X77793) mevalonate kinase [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|4883990|gb|AAD31719.1|AF141853_1 (AF141853) mevalonate kinase [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|7463680|pir||E70185_16:143 mevalonate pyrophosphate decarboxylase homolog - Lyme disease spirochete (Borrelia burgdorferi)
- gi|2688615|gb|AAC67031.1| (AE001169) mevalonate pyrophosphate decarboxylase [Borrelia burgdorferi] (Borrelia burgdorferi)
- gi|6899611|gb|AAF31014.1|AE002158_12_25:149 (AE002158) conserved hypothetical [Ureaplasma urealyticum] (Ureaplasma urealyticum)
- gi|5578718|gb|AAD45421.1|L77688_1_4:224 (L77688) mevalonate kinase [Arabidopsis thaliana] (Arabidopsis thaliana)
- gi|3183371|sp|Q58822|YE27_METJA_13:200 HYPOTHETICAL PROTEIN MJ1427 (Methanococcus jannaschii)
- gi|2128851|pir||B64478 hypothetical protein MJ1427 - Methanococcus jannaschii (Methanococcus jannaschii)
- gi|1592332|gb|AAB99449.1| (U67584) M. jannaschii predicted coding region MJ1427 [Methanococcus jannaschii] (Methanococcus jannaschii)
- gi|629246|pir||S44963_26:168 lmbP protein - Streptomyces lincolnensis (Streptomyces lincolnensis)
- gi|2127561|pir||S69824 lmbP protein - Streptomyces lincolnensis (Streptomyces lincolnensis)
- gi|487706|emb|CAA55762.1| (X79146) lmbP [Streptomyces lincolnensis] (Streptomyces lincolnensis)
- gi|6919910|sp|O25984|IPK_HELPY_37:149 ISOPENTENYL MONOPHOSPHATE KINASE (Helicobacter pylori)
- gi|7464002|pir||C64700 conserved hypothetical protein HP1443 - Helicobacter pylori (strain 26695) (Helicobacter pylori)
- gi|2314615|gb|AAD08481.1| (AE000644) conserved hypothetical protein [Helicobacter pylori 26695] (Helicobacter pylori 26695)
- gi|3183451|sp|O28190|YK89_ARCFU_15:128 HYPOTHETICAL PROTEIN AF2089 (Archaeoglobus fulgidus)
- gi|7429725|pir||H69510 conserved hypothetical protein AF2089 - Archaeoglobus fulgidus (Archaeoglobus fulgidus)
- gi|2648456|gb|AAB89167.1| (AE000960) conserved hypothetical protein [Archaeoglobus fulgidus] (Archaeoglobus fulgidus)
- gi|7445272|pir||B75078_11:116 hypothetical protein PAB1694 - Pyrococcus abyssi (strain Orsay) (Pyrococcus abyssi)
- gi|5458439|emb|CAB49927.1| (AJ248286) hypothetical protein [Pyrococcus abyssi] (Pyrococcus abyssi)
- gi|2909376|emb|CAA76303.1|_15:128 (Y16585) Orf322 [Methanosarcina mazei] (Methanosarcina mazei)
- gi|7447992|pir||H69314_4:151 conserved hypothetical protein AF0520 - Archaeoglobus fulgidus (Archaeoglobus fulgidus)
- gi|2650100|gb|AAB90713.1| (AE001068) conserved hypothetical protein [Archaeoglobus fulgidus] (Archaeoglobus fulgidus)
- gi|7429727|pir||F71066_11:134 hypothetical protein PH1228 - Pyrococcus horikoshii (Pyrococcus horikoshii)
- gi|3257645|dbj|BAA30328.1| (AP000005) 325aa long hypothetical protein [Pyrococcus horikoshii] (Pyrococcus horikoshii)
- gi|7429728|pir||D71246_19:123 hypothetical protein PH0227 - Pyrococcus horikoshii (Pyrococcus horikoshii)
- gi|3256616|dbj|BAA29299.1| (AP000001) 316aa long hypothetical protein [Pyrococcus horikoshii] (Pyrococcus horikoshii)

              10        20           30               40               
              |         |            |                |               
   1 MREIMKVRVKAPCTSANLGVGFDVF...GLCLK..E.....PYDVIEVEA..IDDKEII.....I
   2 SPAKLNLFLYITGQRAD---GYHTL...QTLFQflD.....YGDTISIEL..RDDGDIR.....L
   3 SPAKLNLFLYITGQRAD---GYHTL...QTLFQflD.....YGDTLHIEP..RHDGEIH.....L
   4 APAKLNLFLHILGRRDD---GYHEL...QTLFQflD.....HGDELHFEA..RQDGQVR.....L
   5 SPAKLNLFLYINGKFPN---GYHEL...QTLFQflD.....FGDWLDISI..REQDNQI.....V
   6 APAKLNLFLHILGRRDD---GYHEL...QTLFQflD.....HGDELHFEA..RQDGQVR.....L
   7 SPAKLNLFLYINGKFPN---GYHEL...QTLFQflD.....FGDWLDISI..REQDNQI.....V
   8 MRVKAPGRINIIGEHTDYNDGY-VL...PFAVN..-.....RFVFLTIED..SGKFVFH.....S
   9 -TFFSPGRINLIGEHTDYNGGR-VF...PAAIT..-.....LGTYGAARK..RDDKLLRf11giI
  10 MKVKAPGRINIIGEHTDYNDGY-VL...PFAVN..-.....RYVFLSIEG..SERFIFH.....S
  11 ------FSVTVPGSTANLGPGFDSV...GMALS..-.....RYLKLTVFE..SDKWSFEa....E
  12 APAKLNLDLRITGRREDGYHNIESI...FCLID..-.....LQDTVYLKP..RDDGKII.....L
  13 -YFFSPGRINLIGEHTDYNGGY-VF...PASIT..-.....IGTTGLARL..REDKKVKl11gvI
  14 ------FSVTVPGSTANLGPGFDSV...GMALS..-.....RYLKLTVFE..SDKWSFE.....A
  15 -YFFSPGRINLIGEHTDYNGGY-VF...PASIT..-.....IGTTGLARL..REDNKVKl11gvI
  16 -------KVYAPASSANMSVGFDVL...GAAVT..PvdgalLGDVVTVEA..AQTFSLNn....L
  17 APAKLNLDLRITGRREDGYHNIESI...FCLID..-.....LQDTVYLKP..RDDGKII.....L
  18 -------KVYAPASSANMSVGFDVL...GAAVT..PvdgalLGDVVTVEA..AETFSLNn....L
  19 ------MKILVPATSANLGPGFDCL...GLSLK..-.....LFNETQIQK..SGVFSIS.....I
  20 ------FKIKVPASSANIGPGYDVL...GVGLS..-.....LFLELDVTI..DSSQAQEt14tkE
  21 -------KVYAPASIGNVSVGFDVL...GAAVS..PidgtlLGDCVSVEA..AETFSLQn....A
  22 ---VSSVTVTVPATTANLGPGFDCI...GAALT..-.....LYNKVKFTR..LDAGGLIihv..T
  23 --AFAPGRINLIGEHTDYNGGY-VF...PAAIE..-.....LGTYGLASK..RNDNKICl11gtI
  24 -----PFTVRAPASSANLGPGFDSL...GLSVP..-.....LYTTLRVTP..QDKAEVVp....L
  25 SPAKLNLFLYITGRRAN---GYHDL...QTLFQflD.....HGDELTITA..NNSGNIT.....L
  26 -FFFAPGRVNLIGEHTDYNGGH-VF...PCALT..-.....MGTYAAVAE..RNDGLVRm11giK
  27 ------FKIKVPASSANIGPGYDVL...GVGLS..-.....LFLELDVTI..DSSQAQEt14tkE
  28 -TFFAPGRINLIGEHTDYNGGH-VF...PCAIS..-.....LGTYAAVGT..NEDNAFRl10laL
  29 --------VSVPATSANLGPGFDCL...GLSLN..-.....LRNRFFIEP..SSFHAVK.....L
  30 --FFSPGRINVIGEHTDYNGGH-VF...PAPIS..-.....LGVYGVYGP..RDDKKVRl12veF
  31 APAKLNLFLQITGRRVD---GYHEL...QTVFRllD.....WGDTIHLRV..REDGQIH.....R
  32 --------VSVPATSANLGPGFDCL...GLSLN..-.....LRNRFFIEP..SNIHAVK.....L
  33 --YFSPGRINLIGEHTDYNGGH-VF...PASIT..-.....YGTQGVAAS..RKDNKVLv11gvI
  34 --EIMKVRVKAPCTSANLGVGFDVF...GLCLK..E.....PYDVIEVEA..IDDKEII.....I
  35 HTIQAPGRVNLIGEHTDYNDGF-VL...PCAID..-.....YQTVISCAP..RDDRKVRv11ldE
  36 HTIQAPGRVNLIGEHTDYNDGF-VL...PCAID..-.....YQTVISCAP..RDDRKVRv11ldE
  37 -------KIEVPATTTNFGSGFDTF...GLALS..-.....LTNTFSVDF..SDKYEVQ.....I
  38 -TFFSPGRINLIGEHTDYNGGN-VL...PVAIT..-.....LGTYGAARK..RDDKVLRf11giI
  39 APAKINLFLEILGDRPD---GFHEL...VMVLQsiA.....LGDKITVRA..NGTDDIR.....L
  40 ------FQIKVPASSANIGPGFDVL...GMSLE..-.....EYMTLDVEV..STESGPCvlty.E
  41 ------VVVYAPASIGNVSVGFDVL...GAAVS..PidgtlLGDRVKVEA..GAEAFTLkt...A
  42 HTIQAPGRVNLIGEHTDYNDGF-VL...PCAID..-.....YQTVISCAP..RDDRKVRv11ldE
  43 -PVFVSVKTFAPATVANLGPGFDFL...GCAVD..G.....LGDHVTLRV..DPSVRAGev6seI
  44 -PVFVSVKTFAPATVANLGPGFDFL...GCAVD..G.....LGDHVTLRV..DPSVRAGev6seI
  45 ------MKVLVPATTTNLGAGFDVF...GLALD..-.....LFNEVEFSF..DTKETTI.....E
  46 -------RIYAPATIANFGPGFDVF...GMAIE..E.....PGDEVIVKE..SDSFEIE.....V
  47 -------RIYAPASSANISVGFDTL...GAAIS..PidgslLGDVVQIES..ISTGFELes...A
  48 ----RKVTVTVPGSSANLGPGFDTL...GLALS..-.....VYDTVEVEI..IPSGLEVev...F
  49 LFARSPGRVNLIGEHIDYE-GYSVL...PMAIR..-.....QDTIIAIRK..CEDQKQLr12mcT
  50 LFARSPGRVNLIGEHIDYE-GYSVL...PMAIR..-.....QDTIIAIRK..CEDQKQLr12mcT
  51 ----RKVTVTVPGSSANLGPGFDTL...GLALS..-.....VYDTVEVEI..IPSGLEVev...F
  52 ------FTVSVPATTANIGPGFDCL...GAALG..-.....LYNHVTVTD..PTDPEVDllieaR
  53 LFARSPGRVNLIGEHIDYE-GYSVL...PMAIR..-.....QDTIIAIRK..CEDQKQLr12mcT
  54 LFARSPGRVNLIGEHIDYE-GYSVL...PMAIR..-.....QDTIIAIRK..CEDQKQLr12mcT
  55 -YGESTGKIILIGEHAV-TFGEPAI...AVPFNagK.....IKVLIEALE..SGNYSSI.....K
  56 HLVQAPGRVNLIGEHTDYNDGF-VL...PCAIN..-.....YQTVVAAAK..REDFLVRl11tdE
  57 GYGESNGKIILIGEHAV-TFGEPAI...AIPFTsgK.....VKVLIESLE..KGNYSAI.....Q
  58 -PAAHQARAFAPASVANVAVGFDLL...GYPMD..Q.....VGDTVTVRR..IDTPQVRiaa..I
  59 -YGESTGKIILMGEHAV-TFGQPAI...AIPFN..A.....GKIKVLIES..LDEGNYSsi...T
  60 MIASAPGKIILFGEHAVVY-GRHAV...VSAIN..-.....LRCRVSVRK..SDRFLIR.....S
  61 ------MKIIVPATSANIGPGFDSV...GVAVT..-.....KYLQIEVSE..ERDEWLI.....E
  62 -LASAPAKVILFGEHSVVY-GKPAI...ASAIE..-.....LRTYVRAQF..NDSGNIKi12liV
  63 APAKINLSLDVTRKRPDGYHEVEMI...MTTID..-.....LADRIELTE..LAEDEVR.....V
  64 ------MKIIVPATSANLGAGFDSI...GIAVN..-.....LYLTVEVLG..ESRDWKI.....D
  65 --VSAPGKLYIAGEYAVVETGHPAV...IAAVD..-.....QFVTVTVES..ARKVGSI.....Q
  66 MIIETPSKVILFGEHAVVY-GYRAI...SMAID..-.....LTSTIEIKE..TQEDEIIl15lnE
  67 --VTTPGKLFIAGEYAVVEPGHPAI...IVAVD..-.....QFVTVTVEE..TTDEGSI.....Q
  68 -----SFKIKVPASSANIGPGFDVL...GIGLQ..-.....LYLTITVTI..DPSIDTSsd8llS
  69 ---CSRARARAYSSAANLGPGFDAL...AVALD..A.....YYDEVEVRV..CSGGNSVyvdevE
  70 SYAKLNLYLDVLGKRSD---GYHEI...VGLFQtiS.....LHDTLTVEI..CDRGFYL.....E
  71 YWGKADETYIIPMNN--------SL...SVTLD..R.....FYTETKVTF..DPDFTED.....C
  72 -LASAPAKIILFGEHSVVY-GKPAI...ASAID..-.....LRTYVRAEF..NDSGNIKi12liV
  73 FFARSPGRVNLIGDHIDYN-FFPVL...PMAIA..-.....NDVIAAVNV..NSTNEIIi11lkE
  74 MKVKAPGRINIIGEHTDYNDGY-VL...PFAVN..-.....RYVFLSIEG..SERFIFH.....S
  75 SPAKINLGLWVLGRLPS---GYHEI...LTLYQ..E.....IPFYDEIYI..REGVLRV.....E
  76 FFARSPGRVNLIGDHIDYN-YFPVL...PMAIE..-.....VDVVAAVST..NNNDMIVi12keT
  77 YWGKKDEALIIPMNN--------SI...SVTLE..K.....FYTETKVTF..NDQLTQD.....Q
  78 -QVKAPGKLYIAGEYAVTEPGYKSI...LIAVN..-.....RFVTATIEA..SNKVEGSihskt-
  79 FFARSPGRVNLIGDHIDYN-FFPVL...PMAIS..-.....ADVIVAVNV..NDEPEIVi15ipL
  80 APAKINLGLSVLGVRENGYHDLHSL...MVPLT..-.....VGDELEIRP..AGALTLR.....V
  81 -------------------------...-----..-.....---------..-------.....-
  82 YWGKKNEELILPMNN--------SL...SLTLD..A.....FYTETEVIF..SDSYMVD.....E
  83 VPGKVNLYLAVGDRRED---GYHEL...TTVFH..A.....VSLVDEVTV..RNADVLSlel..V
  84 -KVKSPGRVNLIGEHTDYTYGY-VM...PMAIN..-.....LYTKIEAEK..HGEVILY.....S
  85 SPAKLNIFLQLLGKRED---GFHEI...VTRYQavS.....FGDQLSLSV..SSRDSFQ.....I
  86 ---------VVAASSANLGPGFDSI...GLALS..-.....LCDEIVVET..TDSGLVVvv...D
  87 YWGKKKEKEMVPATS--------SI...SLTLE..N.....MYTETTLSP..LPANVTA.....D
  88 --WAAPGRVNLIGEHTDYNDGF-VM...PFALP..-.....HQAVAAVSR..RDDGILRl10dpV
  89 -------------------------...--AID..K.....PFDEVVVEE..FNEFEII.....S
  90 -QGESSGKIILMGEHAVVY-GEPAI...AFPFY..A.....TKVTAFLEE..LDAMDDQl....V
  91 AHAKVNMHLWVGARRAD---GLHSI...ESVMQ..R.....ITLADSLSL..SRLDIPG.....R
  92 VPAKVNVQLAVGAARPD---GFHDLanvFLAVS..-.....LYDEVTATP..AADGLRVtc...E
  93 YWGKENQAKMIPSTS--------SI...SLTLE..N.....MFTTTSVSF..LPDTATS.....D
  94 SPAKLNLFLKIWGKRFD---NFHEL...TTLYQ..A.....IDFGDTLSL..KNSMKDS.....L
  95 SPAKLNLFLQILGRRED---DFHEI...VTRYQaiA.....FGDQLSLSI..SSRDSLQ.....V
  96 YWGKADEALIIPMNN--------SL...SVTLD..R.....FYTETRVTF..DETLTED.....Q
  97 -IGRAHAKAILLGEHAVVY-GAPAL...ALPIP..Q.....LTVTASVGW..SSEASDS.....A
  98 -LGQATGKIILMGEHAVVY-GEPAI...AFPFQ..A.....TEITAVFTP..AKTMQIDcay..F
  99 YWGKRDERLILPCTT--------SL...SMTLD..V.....FPTTTEVRL..DPAAEHD.....T
 100 -YAKANIFLKLTGFDSRKYHLLESR...FILLK..D.....VFDELELVD..KESDSKK.....E
 101 -------------------------...----Gi.E.....LWTEARVRV..TGDGEVR.....G
 102 -------------------------...---L-..D.....LKVYAKVKL..IDDGKNK.....I
 103 ----------VAASSANLGPGFDSV...GLALS..-.....LYDEIIVET..TDSGLTVtv...D
 104 --------IDLNGERGRLDGGV---...GITLN..E.....PELVVGLEA..SDDMGVE.....F
 105 ---SAPGKVIIFGEHSAVY-NKPAV...AASVS..A.....LRTYLLISE..SSAPDTIe44qeL
 106 ---SAPGKVIIFGEHSAVY-NKPAV...AASVS..A.....LRTYLLISE..SSAPDTIe44qeL
 107 -TGRAHAKAILLGEHAVVY-GTPAL...AMPIP..Q.....LAVTASAGW..SGRSAES.....R
 108 -RASAPGKVIIVGEHFVVRGSL-AI...VAAIG..-.....RRLRVTVRS..GGKGIVL.....E
 109 -------------------------...---FGi.G.....LRVEAEAEL..IDSGVEC.....I
 110 -KARAPGKIILAGEHAVVH-GSTAV...AAAID..-.....LYTYVTLRF..PLPSAENn48ksI
 111 YWGKKDVFLNIPATS--------SL...AVSVD..K.....FYSISELEL..SNRDEII.....L
 112 -------------------HDFESI...FILVE..N.....IYDDIEITK..IEKNIDD.....V
 113 -KARAPGKIILAGEHAVVH-GSTAV...AAAID..-.....LYTYVTLRFpl-PSNNDRl45ksI
 114 -------LIDLNGSIGRVDGGI---...GLALE..E.....PNIKIEGKE..SDDISIEfdkklI
 115 -------------------HGCRLL...AVALT..A.....HGALRLAEA..PEGVTVR.....A
 116 -------------------------...-----..K.....LKDIISVKS..ALSFS--.....-
 117 --------IDLNGSIGRVDGGV---...GLALE..E.....PHIEIKAKE..SETFVLK.....G
 118 --------LGMIDPTGSLGRRFGSI...GVALE..-.....GGYEIKVTP..AGSLTIE.....A
 119 --------IDLNAEIGRVDGGV---...GITLE..S.....PSLEISASE..ADTVEVV.....G
 120 --------AKAYAAGTVLNALPTGI...GSAFGi.E.....MHTIVKLRP..SDELKVF.....-
 121 -----RLHLGIIDPTGSLGRKFGSI...GVALE..-.....GGYDIKVTP..AGSLTIE.....A
 122 ---------------GDMGRLFGTL...GFAIE..Y.....PYLEVEIET..SEKDKA-.....-


      50        60             70                80        90          
      |         |              |                 |         |          
   1 EVDDKNIPTDPDK.....NVAGIVAKKMIDDF...NIG.....KGVKITIKKGVKAGS....GLG
   2 LTPVEGVEH--ED.....NLIVRAARLLMKTA...ADSgr6tgSGANISIDKRLPMGG....GLG
   3 LTPVNGVEN--ED.....NLIVRAARLLMKVA...SESgr6agSGADISIEKRLPMGG....GLG
   4 HTEIAGVPH--DS.....NLIVRAARGLQEAS...GSP.....QGVDIWLDKRLPMGG....GIG
   5 LTPEIPNLKT-EN.....NLIYRAAKLLQEKA...NIQ.....LGANIHLDKILPMGG....GVG
   6 HTEIAGVPH--DS.....NLIVRAARGLQEAS...GSP.....QGVDIWLDKRLPMGG....GIG
   7 LTPEIPNLKT-EN.....NLIYRAAKLLQEKA...NIQ.....LGANIHLDKILPMGG....GVG
   8 ENMNETVEMEKIEkl...NRWTDYISGVIKAF...EKRgykv.SPVKISVSSNLPMGA....GLS
   9 EISLDHLIFN-KK.....DSWTNYAKGVIKYL...QEAghsidTGMDVYVFGNIPNGS....GLS
  10 ENVNETVEMEKIEkl...NKWTDYISGVIASF...EKRgyrv.SPVKISVSSNLPIGA....GLS
  11 TETVAGIPAG-TD.....NLIYQVAKRTADLY...GKEm....PPVHVKVWSDIPLAR....GLG
  12 HNPVDGMPQ--EA.....DLSYRAASLLQKYA...RTP.....TGVEIWLDKKIPTGA....GLG
  13 EFDLDEVEKK-DG.....ELWSNYVKGMIVML...KGAgyeidKGFELLIKGEIPTAS....GLS
  14 ETETVAGIRG-TD.....NLIYQVAKRTADLY...GKEm....PPVHVKVWSDIPLAR....GLG
  15 EFDLDDVENK-DG.....ELWSNYVKGMIVML...KGAgyeidKGFELLIKGEIPTAS....GLS
  16 GRFADKLPSEPRE.....NIVYQCWERFCQEL...GKQ.....IPVAMTLEKNMPIGS....GLG
  17 HNPVDGMPQ--EV.....DLSYRAASLLQKYA...RNP.....AGVEIWLDKKIPTGA....GLG
  18 GRFADKLPSEPRE.....NIVYQCWERFCQEL...GKQ.....IPVAMTLEKNMPIGS....GLG
  19 GGEGSDNIFLKKN.....NIFVNIFYEIYEKL...SGKk....DNFRFIFQNNIPLSR....GLG
  20 SEGYSTVPLRSDA.....NLITRTALYVLRCN...NIRnfp..SGTKVHVSNPIPLGR....GLG
  21 GRFVSKLPAEPKE.....NIVYQCWERFCQEI...GRE.....VPVAMRLEKNMPIGS....GLG
  22 GKEAEGVNTD-ES.....NLLYQAFVKLYQHIe..QIP.....PSVKIEIDLGVPLAR....GLG
  23 EFSLDELQFD-TT.....HSWANYPKGMVKFL...KESgyqidSGFNILIEGNIPNGA....SLS
  24 GTELADTPAD-ES.....NYVYRAMTLAAKRA...GRTl....PPARVEIETEVPLAR....GLG
  25 SPALADVAL--ED.....NLIYKAAMALKNAA...QSP.....LGADIQLHKVLPMGG....GIG
  26 ECSLDDIRYQ-KE.....DDWANYPKGVIYEF...QQRgyavpHGFDIVFSGNIPNGA....GLS
  27 SEGYSTVPLRSDA.....NLITRTALYVLRCNir.NFP.....SGTKVHVSNPIPLGR....GLG
  28 LTSIFGSFQD-KR.....GLWTDYFQGMARVM...KTAganftHGLNVYINGNLPDGA....GLS
  29 VGEGEGIPKFLTN.....NIFTKVFYEILKKH...GND.....GSFKFLLHNKVPITR....GMG
  30 DIDDTNVEKD-ED.....RFWANYFKGMITYL...REKydgidHGFNLYIEANLPSGS....GLS
  31 IGESVTGVVE-AD.....DLVVRAAYLLKYAT...NVH.....LGADIFVEKRIPVGG....GFG
  32 VGEGEGIPKFLTN.....NIFTKVFYEILKKH...GND.....GSFKFLLHNKVPITR....GMG
  33 SFTLNELEYD-KQ.....AGWANYVKGMILKL...KEAgytfdHGFELLVEGTIPNGA....GLS
  34 EVDDKNIPTDPDK.....NVAGIVAKKMIDDF...NIG.....KGVKITIKKGVKAGS....GLG
  35 FSLDAPIVAH-EN.....YQWANYVRGVVKHL...QLRnnsf.GGVDMVISGNVPQGA....GLS
  36 FSLDAPIVAH-EN.....YQWANYVRGVVKHL...QLRnnsf.GGVDMVISGNVPQGA....GLS
  37 EGYSSGIPKD-QK.....NLFIKVYKKTCQSI...GKKp....KPLKLIQENRVPPAR....GLG
  38 EVPLENLRFE-KE.....HNWTNYPKGVLHFL...QEAghtidSGMDIYIYGNIPNGS....GLS
  39 SCGDSPLAND-AT.....NLAYRAAQLMINNF...PQAhdny.GGVDITLTKHIPMAA....GLA
  40 GDGKEHVSLDVQK.....NMITQTSLYVLRCN...NIStfp..YATKIHVINPIPLGR....GMG
  41 GRFVDKLPANPQE.....NIVYDCWQVFAREL...EKKsvvl.KPLTMTLEKNMPIGS....GLG
  42 FSLDAPIVAH-EN.....YQWANYVRGVVKHL...QLRnnsf.GGVDMVDHGNVPQGA....GLS
  43 TGTTTKLSTNPLR.....NCAGIAAIATMKML...GIRs....VGLSLDLHKGLPLGS....GLG
  44 TGTTTKLSTNPLR.....NCAGIAAIATMKML...GIRs....VGLSLDLHKGLPLGS....GLG
  45 STGKYASDLK-DH.....NLFFEVLRFFERKT...GYRv....PPVRIKQTCNIPVSS....GLG
  46 EGY--DVPRD-EN.....NVAVISAKALFKMV...GEE.....GGVKIRLKKGVRPKS....GLG
  47 GYFVRKLPKEPQK.....NIVYQAYVLFSEQL...KLRganv.KPLRLTLEKNMPIGS....GLG
  48 GEGQGEVPLD-GS.....HLVVKAIRAGLKAA...DAEv....PGLRVVCHNNIPQSR....GLG
  49 YPADPDQEIDLKN.....HKWGHYFICAYKGF...HEYa11spVGLDVLVDGIVPTGS....GLS
  50 YPADPDQEIDLKN.....HKWGHYFICAYKGF...HEYa11spVGLDVLVDGIVPTGS....GLS
  51 GEGQGEVPLD-GS.....HLVVKAIRAGLKAA...DAEv....PGLRVVCHNNIPQSR....GLG
  52 GRDGEKISTT-KD.....NLLYQAIAYFYQQT...GQAi....PPLKLEIDLEIPLAR....GLG
  53 YPADPDQEIDLKN.....HKWGHYFICAYKGF...HEYa11spVGLDVLVDGIVPTGS....GLS
  54 YPADPDQEIDLKN.....HKWGHYFICAYKGF...HEYa11spVGLDVLVDGIVPTGS....GLS
  55 SDVYDGMLYD-AP.....DHLKSLVNRFVELN...NIT.....EPLAVTIQTNLPPSR....GLG
  56 FDLREEIAFQ-PK.....KMWSNYIRGVIKCL...IERgfef.NGADIVVSGNVPQGA....GLS
  57 SDVYDGPLYD-AP.....EHLKSLIGHFVENK...KVE.....EPLLIKIQANLPPSR....GLG
  58 RGIAQPLPLQTER.....NTAGAALLSMHRDL...ALP.....FGFELEIDKGIPLSS....GMG
  59 SDVYDGMLYD-AP.....EHLKSIINRFVEKS...GVK.....EPLSVKIQTNLPPSR....GLG
  60 SLGESGLDYQ-RH.....PYVVQAVKRFGELR...NIP.....-GAEIEIESEIPIGS....GLG
  61 HQIGKWIPHD-ER.....NLLLTIALQIVPDL...Q--.....-PRRLKMTSDVPLAR....GLG
  62 SFSEDKIYFETDYgk7vlSYVRYAIELALEES...DKR.....VGIDVSITSQIPVGA....GLG
  63 SSHNRFVPDD-QR.....NLAYQAAKLIKDRY...NVK.....KGVSIMITKVIPVAA....GLA
  64 HDLGENIPTD-ER.....NLLLTTLSAVLEDK...NVAls...AKFHLKMTSEVPLAR....GLG
  65 SAQYSGMPVRWTRr14pfHYILAAIRLTEKYA...QEKnill.SFYDLKVTSELDSSNgrkyGLG
  66 IKNINPNNFG-DF.....KYCLCAIKNTLDYL...NIEpk...TGFKINISSKIPISC....GLG
  67 SAQYSSLPIRWTRr14pfHYVLAAIHLTEKYA...QEQnkel.SFYHLKVTSELDSSNgrkyGLG
  68 YEGDGKVPFESNE.....NLITQTALYVMRCN...GIKdfp..RGTHIHVNNPIPLGR....GLG
  69 GKFSSGVLQ--GP.....NTAAEAVRGLLNME...GVE.....AEVGIRVYKGVPPGR....GLG
  70 SSVALP-----SD.....NTIKRAWEMFRKNT...GKE.....FGLKVTLKKEIPVGS....GLG
  71 LILNGNEVNAKEK.....EKIQNYMNIVRDLA...GNR.....LHARIESENYVPTAA....GLA
  72 SFSEDKIYFETD-yg8vlSYVRHAIELVLEEA...DKR.....TGVSVSITSQIPVGA....GLG
  73 VIALRNSQIDQEH.....HSWANYFKCALIVA...KQYle9slKGMKLTFNGNVPTGG....GLS
  74 ENVNETVEMEKIEkl...NKWTDYISGVIASF...EKRgyrv.SPVKISVSSNLPIGA....GLS
  75 TNI--GIPQ--EE.....NLVYKGLREFERIT...GIE.....INYSIFIQKNIPPGA....GLG
  76 VSLAEEFTIDREH.....HTWANYFKCGLIVA...SKFlq9klKGMNITFSGTVPTGG....GLS
  77 FWLNGEKVSGKEL.....EKISKYMDIVRNRA...GID.....WYAEIESDNFVPTAA....GLA
  78 -LHYEPVKFDRNEd14qlKYVVTAIEVFEQYV...RSCnmnl.KHFHLTIDSNLADNSgqkyGLG
  79 TNNNDGFEIDSQH.....HSWANYFKCALIVA...NNYl10qlKGMKLTFDGNVPTGG....GLS
  80 EG--ADLPTD-ER.....NLVYRAARAYLDAA...GAA.....GGADLVLHKRLPLAS....GLG
  81 ----------HED.....NLIVRAARLLMKTA...ADSgr6tgSGANISIDKRLPMGG....GLG
  82 FYLDGTLQDEKAT.....KKVSQFLDLFRKEA...GLS.....LKASVISQNFVPTAA....GLA
  83 GEGADQLPTD-ER.....NLAWQAAELMAEHV...GRA.....PDVSIMIDKSIPVAG....GMA
  84 EHFGEERKFSLNDlrke.NSWIDYVKGIFWVL...KESdyev.GGIKGRVSGNLPLGA....GLS
  85 ---INDCQLEISN.....NSIWKSTALFRQYT...GIT.....DPVSWRVVKHIPIGS....GLA
  86 GEGADQVPMG-PE.....HLVVRAVRRGLQAV...GVSa....AGLVVRCRNAIPHSR....GLG
  87 EFYINGQLQNEVE.....HAKMSKIIDRYRPA...GEG.....-FVRIDTQNNMPTAA....GLS
  88 ELRVADLAPG-SD.....KSWTAYPSGVLWAL...REAghel.TGADVHLASTVPSGA....GLS
  89 SGY--PVPNG-ED.....NIALFSAKTLFKML...NIE.....GGLRIKLKKGIRPKS....GLG
  90 SSYYSGNLAE-AP.....HALKNIKKLFIHLK...KQHdiq..KNLQLTIESTIPAER....GMG
  91 CEVCSPYMALPRE.....NTLTRAYARFCQVT...GVH.....DGVRVRVVKRIPAGS....GLG
  92 GPDAGQVPLD-RT.....NLAARAAEALAARY...GRA.....PDVHLHIAKDIPVAG....GMA
  93 QFYINGVLQNDEE.....HTKISTIIDQFRQP...GQA.....-FVKMETQNNMPTAA....GLS
  94 SSNVNELLS--PS.....NLIWKSLEIFRRET...QIH.....QPVSWHLNKSIPLQS....GLG
  95 I---NACHLETPS.....NSIWKSVALFRRYT...GIT.....TPVSWRVVKQIPVGA....GLA
  96 LILNGEAVNAKES.....AKIQRYMEMIRKEA...GIS.....EHALIESENFVPTAA....GLA
  97 GGLSYTMTGTPSR.....ALVTQASDGLHRLT...AEFma9naPHLDVILDGAIPHGR....GLG
  98 TGLLEDVPQ--EL.....ANIKEVVQQTLHFL...KEDt....FKGTLTLTSTIPAER....GMG
  99 AALNGEVATGETL.....RRISAFLSLVREVA...GSD.....QRAVVDTRNTVPTGA....GLA
 100 FEIISNFKC--EN.....NIIQKAYLLLSRRY...NNElkelfSKKSLKLTKNIPVCA....GLG
 101 KIVVKGEEFK-DY.....RLVNSVISVLREVT...GEP.....FGVRFEIHSDIPVGK....GLK
 102 EGKVLDNPNI-KP.....NLIVRCVKNTLDYF...GLN.....YSAYVETKTEIPIKS....GLS
 103 GEGGDQVPLG-PE.....HLVVRAVQHGLQAA...GVSa....AGLAVRCRNAIPHSR....GLG
 104 TSHAEGKLREEYR.....SKIMEAARRTLKHI...GSD.....EKFHFTVRSMFPAHS....GLG
 105 VSLLDPLLAQLSEsfhy.HAAFCFLYMFVCLC...PHA.....KNIKFSLKSTLPIGA....GLG
 106 VSLLDPLLAQLSEsfhy.HAAFCFLYMFVCLC...PHA.....KNIKFSLKSTLPIGA....GLG
 107 GGPTFTMTGSASR.....AVTAQALDGLRRLTasv---ka9dgQHLDVSLDGAIPPGR....GLG
 108 SSMLGRHSAPLPGqg8vsPVLEPYIAVLRSLA...ARGysv..VPHTILVESGIPPRA....GLG
 109 SREGA------DT.....SLMELCTRMVIEHY...GVD.....AGVRVVTSSDLPVAS....GLS
 110 AVLVEEQNLP-KE.....KMWLSSGISTFLWL...YTRiigf.NPATVVINSELPYGS....GLG
 111 NS--KPVILKNRE.....KVFFDYARKILNEP...NVR.....--FKIKSKNNFPTAA....GLA
 112 HYYNETNEIYVYS.....RLVHKTLEWIRHTY...HIK.....NHYRINIKKRIPIGA....GLG
 113 AVLVEEQNLP-KE.....KMWLSSGISTFLWL...YTRiigf.NPATVVINSELPYGS....GLG
 114 EKYGEDYIKS-VR.....DRVYNTAIKVLDVI...GGE.....-GVDLKILSLFPAHS....GLG
 115 FGTETRAEH--AS.....SHPDPLVRAALGYF...GID.....RGVHLTVESDVAPGS....GLG
 116 --LKGDFDCPLEE.....NSLFKALQILKNFL...KSKn10slDTLAIEVEKNIPTQA....GLG
 117 EPI--------NR.....ERFEIAAAKMAEYC...GR-.....-GAEIEVVSDYDAHV....GLG
 118 DEE--------DR.....KVIERVVKELNLKY...ETG.....LDYYIEVRRSIPRHI....GLG
 119 SSL----------.....-LAGRMLKAAKAVI...PEG.....KGIKIHIKRDLPDHV....GLG
 120 -----------VN.....GVERRSIVAERILN...SMD.....VTAEVIVESEIPGGS....GLG
 121 DKE--------DR.....EVIEKIVKELNLEY...ETG.....LDYYIEVRKSIPRHI....GLG
 122 -----------ND.....KDALRFLERLREKY...EFP.....-PVKIEIKHYIPKWV....GLG


       100            110            120          130            140   
        |              |              |            |              |   
   1 SSAASSAGTAYAI.....NELFKL.....NLDKLKLV...DYASYGELASO.....DKVYGIT.I
   2 GGSSNAATVLVAL.....NHLWQC.....GLSMDELA...EMGLTLGADVP.....VFVRGHA.A
   3 GGSSNAATVLVAL.....NHLWQC.....GLSIDELA...TLGLTLGADVP.....VFVRGHA.A
   4 GGSSDAATTLLAL.....NHLWQL.....GWDEDRIA...ALGLRLGADVP.....VFTRGRA.A
   5 GGSSNAATALVSL.....NYLWQA.....NLSIDELA...KLGLTLGADVP.....IFVHGHA.A
   6 GGSSDAATTLLAL.....NHLWQL.....GWDEDRIA...ALGLRLGADVP.....VFTRGRA.A
   7 GGSSNAATALVSL.....NYLWQA.....NLSIDELA...KLGLTLGADVP.....IFVHGHA.A
   8 SSAALEMATAYAI.....SEHFGF.....HLPKLELV...KIAREAEVEFV.....GVRCGIM.D
   9 SSSSLELLIGIMA.....EELFDL.....KLDRLDLV...KIGKRTENDFI.....GVNSGIM.D
  10 SSAALEVATAYAI.....SEYFGF.....NVPKLELV...KIAREAEVEFV.....GVRCGIM.D
  11 SSAAAIVAAIELA.....DELCGL.....KLSEADKL...HLASLEEGHPDn54efPYADAVK.A
  12 GGSSDAATVLLVL.....NRWWQC.....GLTQRQLI...DSGAALGADVP.....FFIFGKN.A
  13 SSASLELLVGVVL.....DDLFNL.....NVPRLELV...QLGQKTENDYI.....GVNSGIL.D
  14 SSAAAIVAAIELA.....DELCGL.....KLSEADKL...HLASLEEGHPDn54efPYADAVK.A
  15 SSASLELLVGVVL.....DDLFKL.....SVPRLELV...QLGQKTENDYI.....GVNSGIL.D
  16 SSACSVVAALMAM.....NEHCGK.....PLNDTRLL...ALMGELEGRISg59qyRRQDCIA.H
  17 GGSSDAATVLLVL.....NRWWQC.....GLTQRQLI...DSGAALGADVP.....FFIFGKN.A
  18 SSACSVVAALMAM.....NEHCGK.....PLNDTRLL...ALMGELEGRISg60qyRRQDCIA.H
  19 SSSAVIVGAIASA.....YYMSGF.....KVEKECIL...DEALIYENHPDn55nlSFNDAVF.N
  20 SSGAAVVAGVILG.....NEVAQL.....GFSKQRML...DYCLMIERHPDn90ayPTQDLVF.N
  21 SSACSVVAGLMAM.....NEFCDR.....PLDKTTLL...GLMGELEGRISg60qyRRQDCIS.H
  22 SSATAIVGGLVAA.....NQLAGE.....PLSQLQVM...ELAIAMEGHPDn55efSRADAIF.N
  23 SSASIEILMGWLL.....KALFNL.....EVERLELI...ELGRKVENQFI.....GVNSGIM.D
  24 SSAAALVAGVVAG.....NELLGR.....PLDDETVL...DVTAREEGHPDn55eySRADTVH.A
  25 GGSSNAATTLVAL.....NYLWQT.....GLSDDQLA...EIGLALGADVP.....VFTRGFA.A
  26 SSASIELLMGVVL.....QSYFHP.....EVDALELV...KMAQHAENHFI.....GVNCGIM.D
  27 SSGAAVVAGVILG.....NEVAQL.....GFSKQRML...DYCLMIERHPDn90ayPTQDLVF.N
  28 SSASLEMLVGTIL.....NSLFDG.....GFEPLELV...QFGVKVENDYI.....GVNSGVM.D
  29 SSSAMIVGAVASA.....FAFLGF.....DFDRENIV...NTALIYENHPDn55rySVQESVF.N
  30 SSAAIEMLMGIIL.....KDEFNL.....DVDRVSLA...KMGQRTENEFI.....GLNSGIM.D
  31 GGSSDAATVLLVL.....NALWHT.....RLDVAVLA...ALGLRLGADVP.....VFVHGCN.A
  32 SSSAMIVGAVASA.....FAFLGF.....AFDRENIL...NTALIYENHPDn55rySVQESVF.N
  33 SSASLELLVGVVL.....EDLFDL.....AIDRLALV...QTGKKVENEFI.....GVNSGIM.D
  34 SSAASSAGTAYAI.....NELFKL.....NLDKLKLV...DYASYGELASSg116kDKVYGIT.I
  35 SSASLEVAVGTVL.....QQLYHL.....PLDGAQIA...LNGQEAENQFV.....GCNCGIM.D
  36 SSASLEVAVGTVL.....QQLYHL.....PLDGAQIA...LNGQEAENQFV.....GCNCGIM.D
  37 SSATAIVGGIEAA.....LALHKV.....ELPLKEKL...KIAFEFEKHPDn55kvELKEAVF.N
  38 SSSSLELLIGVIV.....EKLYDI.....KLERLDLV...KIGKQTENDFI.....GVNSGIM.D
  39 GGSADAAAVLVGL.....DLLWNL.....GLTRPELE...QLAAQLGSDIP.....FCIGGGT.A
  40 SSGSAAIAGVMLA.....NEIAKL.....GLSKLQMM...DYVLMIERHPDn82syGRTDVVY.N
  41 SSACSIVAALDAL.....NQFHAS.....PLDETELL...ALMGEMEGKISg60qyRRQDIVA.H
  42 SSASLEVAVGTVL.....QQLYHL.....PLDGAQIA...LNGQEAENQFV.....GCNCGIM.D
  43 SSAASAAAAAVAV.....NEIFGR.....KLGSDQLV...LAGLESEAKVSg61eiPMVHHVW.N
  44 SSAASAAAAAVAV.....NEIFGR.....KLGSDQLV...LAGLESEAKVSg61eiPMVHHVW.N
  45 SSAAVIVAALHIA.....NEGTGR.....NLSREDLM...KLAVELEGHPDn53kvPFEDAVF.N
  46 SSGASSVAGALAA.....ARVLGV.....DNDELIIM...-AALEGEKAASg58kvPLKDAIK.N
  47 SSACSIVAALVAL.....NQFHNE.....PFSKMELL...EMMGELEGRISg60syTRQNVIA.H
  48 SSAAAAVAGVAAA.....NGLADF.....PLTQEQIV...QLSSAFEGHPDn62evTHIDARF.N
  49 SSAAFVCSATIAI.....MAVFGH.....NFEKKELA...QLTCECERHIG.....TQSGGMD.Q
  50 SSAAFVCSATIAI.....MAVFGH.....NFEKKELA...QLTCECERHIG.....TQSGGMD.Q
  51 SSAAAAVAGVAAA.....NGLADF.....PLTQEQIV...QLSSAFEGHPDn62evTHIDARF.N
  52 SSATAIVGGLLAA.....NQAAGN.....PCTTSEIL...QMAIAMEGHPDn55qyDRSAAIF.N
  53 SSAAFVCSATIAI.....MAVFGH.....NFEKKELA...QLTCECERHIG.....TQSGGMD.Q
  54 SSAAFVCSATIAI.....MAVFGH.....NFEKKELA...QLTCECERHIG.....TQSGGMD.Q
  55 SSAAVAVAFVRAS.....YDFLGK.....SLTKEELI...EKANWAEQIAH.....GKPSGID.T
  56 SSAALEVVIGQTF.....KELYQL.....KISQAEIA...LNGQQAENQFV.....GCNCGIM.D
  57 SSAAVAVAFIRAS.....YDYLGL.....PLTDKELL...ENADWAERIAH.....GKPSGID.T
  58 GSAASCVAALLAA.....NALLEE.....PLRREHLY...RYALDGEAVASg57pyLLPDIVT.Q
  59 SSAAVAVAFVRAS.....YDFMDQ.....PLDDKTLI...KEANWAEQIAH.....GKPSGID.T
  60 SSAAVIVATIAAL.....NAEFDG.....DMDKEAIF...QMAKQVEIDVQ.....GRASGID.P
  61 SSSSVIVAGIELA.....NQLGQL.....NLSDHEKL...QLATKIEGHPDn59eaVAASSIA.N
  62 SSAAVAVATIGAV.....SRLLGL.....ELSKEEIA...KLGHKVELLVQ.....GASSGID.P
  63 GGSSDAAATLRGL.....NRLWNL.....NLSAETLA...ELGAEIGSDVS.....FCVYGGT.A
  64 SSSSVIIAGIELA.....NQLAKL.....NLTSDEKL...KLACEIEGHPDn54elTYKEAVA.A
  65 SSGAVTVATVKAL.....NVFYAL.....NLSQLEIF...KIAALANLAVQ.....DNGSCGD.I
  66 SSASITIGTIKAV.....SGFYNK.....ELKDDEIA...KLGYMVEKEIQ.....GKASITD.T
  67 SSGAVTVGTVKAL.....NIFYDL.....GLENEEIF...KLSALAHLAVQ.....GNGSCGD.I
  68 SSASAIVAGVYLG.....NEIGNL.....KLDKYRLL...DYCLMIERHP-.....-------.-
  69 SSGASAAAAVAAV.....SHALAL.....EVPVDRLV...FYAGLGERAAAg63nvSFRDAVR.N
  70 GGSSNAAAVLRYL.....GEVFKI.....PL--EDLL...NIAAQVGSDVP.....FFLYGGT.A
  71 SSASAYAALAAAC.....NEALSL.....NLSDTDLS...RLARRGSGSAS.....RSIFGGF.A
  72 SSAAVAVATIGAV.....SKLLDL.....ELSKEEIA...KMGHKVELLVQ.....GASSGID.P
  73 SSAAFCVASTLAI.....IRANGIt....DLTKQDLT...RITVVSEHYVG.....VNTGGMD.Q
  74 SSAALEVATAYAI.....SEYFGF.....NVPKLELV...-----------.....-------.-
  75 GGSSNLAVVLKKV.....NELLGS.....PLSEEELR...ELVGSISADAP.....FFLLGKS.A
  76 SSAAFCVASTLAV.....LYANGVe....DISKADLT...RITVVSEHYLG.....LNNGGMD.Q
  77 SSASAYAALAAAC.....NQALDL.....QLSDKDLS...RLARIGSGSAS.....RSIYGGF.A
  78 SSAAVLVSVVKAL.....NEFYGL.....ELSNLYIY...KLAVIANMKLQ.....SLSSCGD.I
  79 SSAAFCVASTLAI.....LHANGVk....DITKADLT...RITVVCEHYVG.....VNTGGMD.Q
  80 GGSSDAASTLLAL.....AELYPAp....DHRPVDLP...ALALTLGADVP.....FFLLGGA.A
  81 GGSSNAATVLVAL.....NHLWQC.....GLSMDELA...EMGLTLGADVP.....VFVRGHA.A
  82 SSASGLAALAGAC.....NTALKL.....GLDDLSLS...RFARRGSGSAC.....RSIFGGF.V
  83 GGSADAAAVLVAM.....NSLWEL.....NVPRRDLR...MLAARLGSDVP.....FALHGGT.A
  84 SSASFEVGILETL.....DKLYNL.....KLDSLSKV...LLAKKAENEFV.....GVPCGIL.D
  85 GGSSNAATALFAL.....NQMFQT.....GLSDEELR...SLAEKVGMDTP.....FFFSSGS.A
  86 SSAAAVVGGLAVV.....NGFVAQidst.PLSNAQLI...QLASEFEGHPD.....NAAAAVL.G
  87 SSSSGLSALVKAC.....NAYFKL.....GLDRSQLA...QEAKFASGSSS.....RSFYGPL.G
  88 SSAALEVVLALAM.....NDLYAL.....GLRGWQLA...RLCQRAENVYV.....GAPVGIM.D
  89 SSGASAVAGALGA.....AKLLGV.....SNDELILK...AAMKGEEKASGe57mvPLKDAVK.N
  90 SSAAVATAVTRAF.....YDYLAF.....PLSREILL...ENVQLSEKIAH.....GNPSGID.A
  91 GGSADAAALLCGL.....DTLFGT.....TLSARVLR...EVAYSVGSDVP.....FFLASQA.A
  92 GGSADGAGALLAC.....DALWGT.....GASREELL...EICAGLGSDVP.....FSLVGGA.A
  93 SSSSGLSALVKAC.....DQLFDT.....QLDQKALA...QKAKFASGSSS.....RSFFGPV.A
  94 GGSSNAATALYAL.....NEHFQT.....HIPITTLQ...LWAREIGSDVP.....FF-----.-
  95 GGSSNAATALFAL.....NQIFKT.....GLSDEEMR...SLAEQLGVDTP.....FFFSTGA.A
  96 SSASAYAALAGAC.....NEALQL.....GLSDKDLS...RLARRGSGSAS.....RSIYGGF.A
  97 SSAAGSRAIALAL.....ADLFGH.....ELAEHTAY...ELVQTAENMAH.....GRASGVD.A
  98 SSAATAVAIVRSL.....FDYFDY.....AYTYQELF...ELVSLSEKIAH.....GNPSGID.A
  99 SSASGFAALAVAA.....AAAYGL.....ELDDRGLS...RLARRGSGSAS.....RSIFGGF.A
 100 GGSSDCASFLLLI.....NETLNL.....KLNLQELI...NLSIQLGSDIA.....FFLSGFHsA
 101 SSSAAANSLTKAL.....VEALRL.....NIDDLSIV...KLGVEAAKRAG.....VTITGAF.D
 102 SSSATSNAVVLAT.....FDALGE.....KIDDELIL...NLGIKSSFDEK.....LTVTGAY.D
 103 SSAAAVVGGLAAV.....NGLVVQtdss.PSSDAELI...QLASEFEGHPDn35di-------.-
 104 SGTQLSLATARLV.....AEYHGM.....KFTARELA...HIVGRGGTSGI.....GVAS---.-
 105 SSASISVSLALAM.....AYLGGLi10lsENDKHIVN...QWAFIGEKCIH.....GTPSGID.N
 106 SSASISVSLALAM.....AYLGGLi10lsENDKHIVN...QWAFIGEKCIH.....GTPSGID.N
 107 SSAANARAIILAL.....ADLFGR.....ELTEGEVF...DLVQEAENLTH.....GRASGVD.A
 108 SSAASMVAYALSY.....SAMHGD.....PLSAEDLY...SVAMEGEKIAH.....GKPSGVD.V
 109 SSSAASNATVMAV.....SSLLSDefglqPMEDFEML...NMAVDASLQAG.....VSVTGAY.D
 110 SSAALCVALTAALl11rgNGWSSL.....DETNLELLn..KWAFEGEKIIH.....GKPSGID.N
 111 SSSSGFASIAACI.....LKYFN-.....KYSCNSAS...NLARVGSASAA.....RAIYGGF.-
 112 GGSSNAAAIMKYI.....LEFEG-.....-IKEINYK...DVVNKLGADIP.....FFLSGYK.T
 113 SSAALCVALTAALl11rgNGWSSL.....DETNLELLn..KWAFEGEKIIH.....GKPSGID.N
 114 SGTQLSLAVGKLI.....SKIYNK.....EMNAYNIA...KITGRGGTSGIg25keDFRPSSA.S
 115 GSGAFLVALATAL.....SHLTGD.....PLTPAAAA...RAAFRIERALC.....GRPVGQQ.D
 116 GGSTDAGGLLYHL.....NQIFDW.....RLSLEELY...SMGSLVGADTN.....FFIS---.-
 117 SGTQISLAVGRAF.....SELYGL.....NLTTRQIA...EIMGRGGTSGIg....-------.-
 118 STTQLTLAIASAI.....LRIAKK.....EVPIEDVA...-----------.....-------.-
 119 SGTQAALSVAAAI.....NEIYGL.....GKSVRELA...VAVGRGGTSGIgv...-------.-
 120 SSSAFVNALICAV.....KKMKGE.....ELNAFEIL...RSNARFSLEAG.....ISYTGAF.D
 121 STTQLTLAIASAI.....LRIAKK.....DIPIEEVAfslKRARESGAGLY.....I------.-
 122 FHTTLALTLGLGI.....NRIYNL.....GLSLEDIA...LTVRRGLITAL.....-------.-


                150        160        170       180    
                 |          |          |         |    
   1 SGSGPS.....IIAFPKEEFID.EVENILR.DYYENTIRTEVGKGVEVV
   2 FAEGVG.....EILTPVDPPEK.WYLVAHP.GVSIPTPVIFKDPEL---
   3 FAEGVG.....EILTPVNPPEK.WYLVAHP.GVSIPTPVIFKDPQL---
   4 FAEGVG.....EKLTPVDIPEP.WYLVVVP.QVLVSTAEIFSDPLL---
   5 FAEGVG.....EKITYCEPAEK.WFVILKP.DDSISTAVIFQDPNL---
   6 FAEGVG.....EKLTPVDIPEP.WYLVVVP.QVLVSTAEIFSDPLL---
   7 FAEGVG.....EKITYCEPAEK.WFVILKP.DDSISTAVIFQDPNL---
   8 QFTSAFgk6haIFLDTMTLEYE.YVPLKLE.GYEINLVDSNVKHEL---
   9 QFAIGMga6kaIYLDTKTLEYD.LVPLDLG.DNVIVIMNTNKRREL---
  10 QFTAVFgk6haIFLDTMTLEYE.YVPLKLE.GYEINLVDSNVKHEL---
  11 SAVSNI.....LIAAIMSKDWP.LVGKIMKkDMFHQPYRAMLVPELSKV
  12 FARGIG.....DRLDEMDIPKQ.WYVIVKP.PVHVSTAKIFTHEGL---
  13 QFAIGFge6kaILLDCNTLKYE.MVPVELR.DYDIVIMNTNKPRAL---
  14 SAVSNI.....LIAAIMSKDWP.LVGKIMKkDMFHQPYRAMLVPELSKV
  15 QFAIGFge6kaILLDCNTLKYE.MVPVELR.DYDIVIMNTNKPRAL---
  16 GRHLAG.....FIHACYSRQPE.LAAKLMK.DVIAEPYRERLLPGF---
  17 FARGIG.....DRLDEMDIPKQ.WYVIVKP.PVHVSTAKIFTHESL---
  18 GRHLAG.....FIHACYSRQPE.LAAKLMK.DVIAEPYRERLLPGF---
  19 LSHASF.....LTACFLEKKYE.FLKFASQ.DKLHEINRMKNLPELFEV
  20 LQRLAVlt...TALTMDPPNAD.LIYPAMQ.DRVHQPYRKTLIPGLTEI
  21 GRYLAG.....FIHACHTRQPQ.LAAKLMQ.DVIAEPYRTRLLPGF---
  22 TAHLGL.....LLRGLATGKGE.WLKTALQ.DKLHQPYRKALIPGYDAV
  23 QFIVGMgr6qaILLDTATLEYH.YVPTEFG.DYVISIMNTNKRREL---
  24 LSHAAL.....LAAALAQGRLD.LLRHAMQ.DYVHQVWRAPLVPGLSDI
  25 FAEGVG.....EELSAVEPEEK.WYLVVRP.AVSIATKDIFTHPQL---
  26 QFAIGMgk6haMLLNCDTLDYE.YSKLNVS.GLALVIANTNKKRTL---
  27 LQRLAVlt...TALTMDPPNAD.LIYPAMQ.DRVHQPYRKTLIPGLTEI
  28 QFAIEMgr6qaTLLDTNTMKYE.YLPVEMG.DNVIVIMNTNKRREL---
  29 LSHASL.....MTMAIVQGKWD.LLRCCSK.DRMHQYKRMQTYPVLF--
  30 QFACIMgk6saIFLDCNTLKYE.YLPLALG.DYEIIIMATNNPHT----
  31 WAEGVG.....ECLTPMILPGA.AYLLLDP.GVCVPTRELFLDPDL---
  32 LSHASL.....MTMAIVQGKWD.LLRCCSK.DRMHQYKRMQTYPVLF--
  33 QFAIGFge6kaILLDTNTLKYE.MVPVKLD.GYAVVIMNTNKRREL---
  34 SGSGPS.....IIAFPKEEFID.EVENILR.DYYENTIRTEVGKG----
  35 QLISAL.....-----------.-------.------------------
  36 QLISAL.....-----------.-------.------------------
  37 VQRSAL.....FVSALLTKDYK.LLREAVR.DKLHQPYREKLVPGLS--
  38 QFAIGMga6caIYLDTNTLKYD.LVPLDLK.DNVVVIMNTNKRREL---
  39 IATGRG.....EILDPLPDGNC.FWVVLAK.HRSI--------------
  40 LQRLALlt...TALGQTPINPH.LVYEVMK.DKVHQPYRASLIPGLQNI
  41 GRYLAG.....FIHACHTQQPE.LAAKMIK.DVIAEPYREKLLPGF---
  42 QLISAL.....-----------.-------.------------------
  43 SSQAAA.....LVAAVLEGDAV.MLGKALSsDKIVEPTRAPLIPGMEAV
  44 SSQAAA.....LVAAVLEGDAV.MLGKALSsDKIVEPTRAPLIPGMEAV
  45 IKNSCQ.....FLAKIAAGKIK.EALKYVG.DRLHQNYRINGNKKMK--
  46 LAMASS.....LVLALKEGDIE.TVGRLLD.DNLALPYRKKLMPWFDEV
  47 GRHLGG.....FVHACHTHQEN.LAAIMMK.DVIAEPYRESLLPNFAEV
  48 VSRVAV.....MIVALQQ-RPD.LLWEGTR.DRLHQPYRAEVLP-----
  49 AISI--.....-----------.-------.------------------
  50 AISI--.....-----------.-------.------------------
  51 VSRVAV.....MIVALQQ-RPD.LLWEGTR.DRLHQPYRAEVLP-----
  52 ASHLAL.....LVQAFSQGRGD.WLALALQ.DQIHQPYRQSLIPAYDQ-
  53 AISI--.....-----------.-------.------------------
  54 AISI--.....-----------.-------.------------------
  55 QTIVSG.....KPVWFQKGQAE.TLKTLSL.DGYMVVI-----------
  56 QMISAQgqa..-----------.-------.------------------
  57 KTIVTN.....QPVWYQKGEVE.ILKTLDL.DGYMVVI-----------
  58 SANLAL.....VLAGCYHGDAE.LVRAGLR.DVLIEPRRAPLIAGF---
  59 QTIVSN.....KPVWFKQGQAE.TLKSLKL.NGYMVV------------
  60 FISTFGg....SWLFPE-----.-------.------------------
  61 VAVAAL.....LAGDMVTAG--.--QAIEG.DLFHERYRQDLVREF---
  62 TVSAVG.....GFLYYKQGKFE.PLPFME-.------------------
  63 LATGRG.....EKIKHISTPPH.CWVILAK.P-----------------
  64 SSIANV.....LTASLLTNNLE.VAGQMMEaDRFHESYRASLIPELQ--
  65 AASCYG.....GWIAFSTFDHP.WLQEQET.QHSISELLALDWPGL---
  66 STITYK.....GILEIKNNKFR.KIK----.------------------
  67 AASCYG.....GWIAFSTFDHD.WVNQKVT.TETLTDLLAMDWPEL---
  68 ------.....-----------.-------.------------------
  69 FSRAAG.....IVAAAVNGDLKsMGALMMS.DEIVEPRRRSYVPCYTQV
  70 LVRGRG.....EIVEKLED---.-------.------------------
  71 EWEKG-.....-----------.-------.------------------
  72 TVSAIG.....GFLYYKQGEFE.HLPFV--.------------------
  73 CASVCG.....E----------.-------.------------------
  74 ------.....-----------.-------.------------------
  75 IGRGKG.....EVLEPVETE--.-------.------------------
  76 CASVYGeq...GKALFIQFKP-.-------.------------------
  77 EWEKGY.....-----------.-------.------------------
  78 AVSVYS.....GWLAYSTFDHD.WVKQQME.ETSVNDVLEKNWPGL---
  79 CASVYGep...DKALLIQFK--.-------.------------------
  80 LAEGVG.....ERLTPVDD---.-------.------------------
  81 FAEGVG.....EILTPVDPPEK.WYLVAHP.GVSIPTPVIFKDPEL---
  82 EWEKGHdd9kpVPSDSFEDDLA.MVFVLIN.D-----------------
  83 LGTGRG.....EELA-------.-------.------------------
  84 QFAVVFgr6nvIFLDTHTLDYE.YIPF---.------------------
  85 LGLGRG.....EKV--------.-------.------------------
  86 GAVVSW.....VDRSYDQPDYC.AVPLRLH.PDIH--------------
  87 AWDKDS.....GEIYPVETDLK.LAMIM--.------------------
  88 QTAS--.....-----------.-------.------------------
  89 IAMASS.....LILALKEGDLE.TIGRLLD.DNLALPYRKKLMPWFDEI
  90 AATSSL.....QPIYFTKG---.-------.------------------
  91 CVLGGG.....EQLVPLVPKTG.YLGLLVW.PGL---------------
  92 LGTGRG.....ERLAELEVGGD.-------.------------------
  93 AWDKDS.....GAIYKVETDLK.MAMI---.------------------
  94 ------.....-----------.-------.------------------
  95 LGVARG.....EKIIAL-----.-------.------------------
  96 EWEK--.....-----------.-------.------------------
  97 MTVGAS.....RPLLFQQGRTE.RLAIGCD.S-----------------
  98 AATSGA.....DPLFFTRGFP-.-------.------------------
  99 VWHA--.....-----------.-------.------------------
 100 NVSSCG.....EIIEEFEDDIP.NLKWTFP.QISCQ-------------
 101 DACASY.....FGGLCITDNYE.MEILVKR.EINPETVV----------
 102 DATASY.....YGGITITDNIE.RKILKRD.KMRDDLNVLILIPNLE--
 103 ------.....-----------.-------.------------------
 104 ------.....-----------.-------.------------------
 105 AVATYG.....NALLFEKDSH-.-------.------------------
 106 AVATYG.....NALLFEKDS--.-------.------------------
 107 VTVGAT.....APLLF------.-------.------------------
 108 TIAVRG.....GVLAYRRG---.-------.------------------
 109 DASASF.....YGGLTVTDNME.RRIILRE.PMEN--------------
 110 TVSAYG.....NMIKFCSGEIT.RLQS---.------------------
 111 ------.....-----------.-------.------------------
 112 AYIS--.....-----------.-------.------------------
 113 TVSAYG.....NMIKFCSGEIT.RLQS---.------------------
 114 KGVKPA.....PIIFRHDFDWE.TILIIPK.GEHV--------------
 115 HWTAAS.....GAAIELRIAPD.GTADA--.------------------
 116 ------.....-----------.-------.------------------
 117 ------.....-----------.-------.------------------
 118 ------.....-----------.-------.------------------
 119 ------.....-----------.-------.------------------
 120 DASASM.....LGGFVVSDNRK.MRLIRTD.E-----------------
 121 ------.....-----------.-------.------------------
 122 ------.....-----------.-------.------------------