CASP4 Target T0112

1. Protein Name: Ketose Reductase / Sorbitol Dehydrogenase
2. Organism Name: Bemisia argentifolii
3. Number of amino acids (approx): 352
4. Accession number: O96496
5. Sequence Database: Swiss-prot
6. Amino acid sequence: MASDNLSAVL YKQNDLRLEQ RPIPEPKEDE VLLQMAYVGI CGSDVHYYEH GRIADFIVKD
PMVIGHEASG TVVKVGKNVK HLKKGDRVAV EPGVPCRRCQ FCKEGKYNLC PDLTFCATPP
DDGNLARYYV HAADFCHKLP DNVSLEEGAL LEPLSVGVHA CRRAGVQLGT TVLVIGAGPI
GLVSVLAAKA YGAFVVCTAR SPRRLEVAKN CGADVTLVVD PAKEEESSII ERIRSAIGDL
PNVTIDCSGN EKCITIGINI TRTGGTLMLV GMGSQMVTVP LVNACAREID IKSVFRYCND
YPIALEMVAS GRCNVKQLVT HSFKLEQTVD AFEAARKKAD NTIKVMISCR QG
7. Additional Information: Protein is a member of the medium-chain dehydrogenase/reductase
(MDR) family (includes Zinc-containing alcohol dehydrogenases).

The crystals of the protein were grown at pH 8.75.

The protein is a tetramer in solution.
8. Homologous Sequence of known structure: yes
9. Current state of the experimental work: Co-ordinates for this protein structure have already been
submitted to the PDB. They are on-hold until publication.
10. Interpretable map?: yes
11. Estimated date of chain tracing completion: Done
12. Estimated date of public release of structure: Sept. 2000
13. Name: Unavailable until after public release of structure