a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1999.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0106 Secreted frizzled protein 3, mouse
- gi|6755476|ref|NP_035486.1|_33:157 secreted frizzled-related sequence protein 3 (Mus musculus)
- gi|1688097|gb|AAC53135.1| (U68058) frezzled [Mus musculus] (Mus musculus)
- gi|1917011|gb|AAB51300.1| (U91905) Fritz [Mus musculus] (Mus musculus)
- gi|1946345|gb|AAC53147.1| (U88568) secreted frizzled related protein sFRP-3 [Mus musculus] (Mus musculus)
- gi|1620539|gb|AAC48662.1|_33:157 (U24164) Frzb precursor [Bos taurus] (Bos taurus)
- gi|1688095|gb|AAC51217.1|_33:157 (U68057) frezzled [Homo sapiens] (Homo sapiens)
- gi|6746600|gb|AAF27643.1|AF218057_1_25:150 (AF218057) Frzb [Gallus gallus] (Gallus gallus)
- gi|1917007|gb|AAB51298.1|_33:157 (U91903) Fritz [Homo sapiens] (Homo sapiens)
- gi|4503789|ref|NP_001454.1|_33:157 frizzled-related protein (Homo sapiens)
- gi|1620541|gb|AAC50736.1| (U24163) Frzb precursor [Homo sapiens] (Homo sapiens)
- gi|4545254|gb|AAD22462.1|AF116853_1_30:155 (AF116853) fzb-1 [Danio rerio] (Danio rerio)
- gi|2293564|gb|AAB65431.1|_23:148 (AF012891) frizzled related protein frpAP [Rattus norvegicus] (Rattus norvegicus)
- gi|7710094|ref|NP_057896.1|_23:148 secreted frizzled-related sequence protein 4 ()
- gi|4219090|gb|AAD12306.1| (AF117709) secreted frizzled-related sequence protein 4 [Mus musculus] (Mus musculus)
- gi|4506895|ref|NP_003005.1|_23:148 secreted frizzled-related protein 4 (Homo sapiens)
- gi|2920804|gb|AAC04617.1| (AF026692) frpHE [Homo sapiens] (Homo sapiens)
- gi|7672423|gb|AAF66480.1|AF140346_1_23:148 (AF140346) frizzled related protein [Rattus norvegicus] (Rattus norvegicus)
- gi|1688099|gb|AAC60113.1|_29:150 (U68059) frezzled [Xenopus laevis] (Xenopus laevis)
- gi|1854030|gb|AAC60114.1|_29:150 (U78598) Frzb precursor [Xenopus laevis] (Xenopus laevis)
- gi|7672425|gb|AAF66481.1|_23:148 (AF140347) frizzled related protein [Rattus norvegicus] (Rattus norvegicus)
- gi|103213|pir||S15709_52:169 hypothetical protein - fruit fly (Drosophila melanogaster) (Drosophila melanogaster)
- gi|804980|emb|CAA38461.1| (X54648) frizzled (clone BE2) [Drosophila melanogaster] (Drosophila melanogaster)
- gi|120529|sp|P18537|FRIZ_DROME_52:169 FRIZZLED PROTEIN PRECURSOR (Drosophila melanogaster)
- gi|84965|pir||S03540 gene frizzled protein precursor - fruit fly (Drosophila melanogaster) (Drosophila melanogaster)
- gi|103211|pir||S15708 hypothetical protein - fruit fly (Drosophila melanogaster) (Drosophila melanogaster)
- gi|7981|emb|CAA38458.1| (X54646) frizzled [Drosophila melanogaster] (Drosophila melanogaster)
- gi|804979|emb|CAA38460.1| (X54648) frizzled (clone AC2) [Drosophila melanogaster] (Drosophila melanogaster)
- gi|226291|prf||1505374A Fz protein [Drosophila melanogaster] (Drosophila melanogaster)
- gi|882059|gb|AAB38383.1|_58:175 (L43163) tissue polarity protein [Drosophila virilis] (Drosophila virilis)
- gi|7527456|gb|AAF63152.1|AF039215_1_35:157 (AF039215) transmembrane receptor frizzled-7 [Xenopus laevis] (Xenopus laevis)
- gi|7983|emb|CAA38459.1|_52:169 (X54647) frizzled [Drosophila melanogaster] (Drosophila melanogaster)
- gi|4469405|gb|AAD21247.1|_35:157 (AF114151) frizzled-7 [Xenopus laevis] (Xenopus laevis)
- gi|6679885|ref|NP_032083.1|_47:168 frizzled homolog 7 (Drosophila) (Mus musculus)
- gi|1151258|gb|AAC52432.1| (U43320) transmembrane receptor [Mus musculus] (Mus musculus)
- gi|5815434|gb|AAD52671.1|_35:157 (AF179213) frizzled 7 [Xenopus laevis] (Xenopus laevis)
- gi|5524663|gb|AAD44331.1|_34:156 (AF159106) frizzled 7 [Xenopus laevis] (Xenopus laevis)
- gi|5262975|emb|CAB45875.1|_35:157 (AJ243323) Frizzled 7 protein [Xenopus laevis] (Xenopus laevis)
- gi|3434981|dbj|BAA32424.1|_47:168 (AB010881) FzE3 [Homo sapiens] (Homo sapiens)
- gi|4503833|ref|NP_003498.1|_47:168 frizzled 7 (Homo sapiens)
- gi|7451365|pir||JE0339 Frizzled-7 protein - human (Homo sapiens)
- gi|3927887|dbj|BAA34668.1| (AB017365) frizzled-7 [Homo sapiens] (Homo sapiens)
- gi|7340122|gb|AAF61095.1|AF224315_1_4:126 (AF224315) Frizzled-2 [Gallus gallus] (Gallus gallus)
- gi|6863203|gb|AAC12873.2|_109:230 (AF054623) Frizzled-1 [Mus musculus] (Mus musculus)
- gi|6273776|gb|AAF06359.1|AF139165_1_36:159 (AF139165) frizzled-2 [Xenopus laevis] (Xenopus laevis)
- gi|2655274|gb|AAB87968.1|_68:189 (AF031830) 7-transmembrane protein frizzled-1 [Gallus gallus] (Gallus gallus)
- gi|310115|gb|AAA41172.1|_42:164 (L02530) Drosophila polarity gene (frizzled) homologue [Rattus norvegicus] (Rattus norvegicus)
- gi|3983449|gb|AAC83940.1|_29:150 (AF039410) frizzled homolog [Danio rerio] (Danio rerio)
- gi|7340126|gb|AAF61097.1|AF224317_1_45:165 (AF224317) Frizzled-7 [Gallus gallus] (Gallus gallus)
- gi|6679887|ref|NP_032084.1|_33:154 frizzled homolog 8 (Drosophila) (Mus musculus)
- gi|1151260|gb|AAC52433.1| (U43321) transmembrane receptor [Mus musculus] (Mus musculus)
- gi|4503825|ref|NP_003496.1|_114:235 frizzled 1; Wnt receptor (Homo sapiens)
- gi|7451366|pir||JE0337 Frizzled-1 protein - human (Homo sapiens)
- gi|3927883|dbj|BAA34666.1| (AB017363) frizzled-1 [Homo sapiens] (Homo sapiens)
- gi|4503827|ref|NP_001457.1|_37:159 frizzled 2 (Homo sapiens)
- gi|7451364|pir||JE0338 Frizzled-2 protein - human (Homo sapiens)
- gi|736679|gb|AAB46397.1| (L37882) polarity gene; putative [Homo sapiens] (Homo sapiens)
- gi|3927885|dbj|BAA34667.1| (AB017364) frizzled-2 [Homo sapiens] (Homo sapiens)
- gi|8248134|gb|AAF74056.1|AF206321_1_42:164 (AF206321) frizzled 10 [Mus musculus] (Mus musculus)
- gi|5305407|gb|AAD41636.1|AF072872_1_115:236 (AF072872) frizzled 1 [Homo sapiens] (Homo sapiens)
- gi|7110524|gb|AAF36979.1|AF231711_1_49:170 (AF231711) 7-transmembrane receptor frizzled-1 [Xenopus laevis] (Xenopus laevis)
- gi|4335927|gb|AAD17520.1|_29:150 (AF060696) frizzled 8b protein [Danio rerio] (Danio rerio)
- gi|2655276|gb|AAB87969.1|_45:165 (AF031831) 7-transmembrane protein frizzled-7 [Gallus gallus] (Gallus gallus)
- gi|4585283|gb|AAD25360.1|AF117390_1_29:150 (AF117390) frizzled protein; fz6 [Danio rerio] (Danio rerio)
- gi|348411|pir||A45054_109:229 probable intercellular signal transducer or transmitter Fz-1 - rat (Rattus norvegicus)
- gi|310117|gb|AAA41173.1|_109:229 (L02529) Drosophila polarity gene (frizzled) homologue [Rattus norvegicus] (Rattus norvegicus)
- gi|6649950|gb|AAF21645.1|AF039412_1_28:149 (AF039412) frizzled homolog [Danio rerio] (Danio rerio)
- gi|4585281|gb|AAD25359.1|AF117389_1_28:149 (AF117389) frizzled protein; fz5 [Danio rerio] (Danio rerio)
- gi|4164471|gb|AAD05435.1|_28:149 (AF060697) frizzled 8a protein [Danio rerio] (Danio rerio)
- gi|4585279|gb|AAD25358.1|AF117388_1_33:156 (AF117388) frizzled protein; fz4 [Danio rerio] (Danio rerio)
- gi|6649948|gb|AAF21644.1|AF039411_1_33:156 (AF039411) frizzled homolog [Danio rerio] (Danio rerio)
- gi|5821259|dbj|BAA83742.1|_36:160 (AB023806) Frizzled-10 [Gallus gallus] (Gallus gallus)
- gi|7340132|gb|AAF61100.1|AF224320_1 (AF224320) Frizzled-10 [Gallus gallus] (Gallus gallus)
- gi|5524665|gb|AAD44332.1|_32:155 (AF159107) frizzled 9 [Xenopus laevis] (Xenopus laevis)
- gi|7494607|pir||T42210_35:143 Frizzled-1 protein homolog - Caenorhabditis elegans (Caenorhabditis elegans)
- gi|7508290|pir||T25162 hypothetical protein T23D8.1 - Caenorhabditis elegans (Caenorhabditis elegans)
- gi|2463674|gb|AAC47750.1| (AF013953) mom-5 gene product [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|3880075|emb|CAB03398.1| (Z81128) predicted using Genefinder~Similarity to Drosophila Tissue polarity protein (TR:Q24760)~cDNA EST yk471e5.5 comes from this gene [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|7305481|ref|NP_038862.1|_58:180 secreted frizzled-related sequence protein 1 (Mus musculus)
- gi|1946341|gb|AAC53145.1| (U88566) secreted frizzled related protein sFRP-1 [Mus musculus] (Mus musculus)
- gi|7451362|pir||S71786_62:181 wingless receptor precursor dfz2 - fruit fly (Drosophila melanogaster) (Drosophila melanogaster)
- gi|7293818|gb|AAF49184.1|_62:181 (AE003518) fz2 gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|1518051|gb|AAC47273.1|_62:181 (U65589) Dfz2 [Drosophila melanogaster] (Drosophila melanogaster)
- gi|4585277|gb|AAD25357.1|AF117387_1_43:162 (AF117387) frizzled protein; fz2 [Danio rerio] (Danio rerio)
- gi|6005762|ref|NP_009128.1|_33:156 frizzled (Drosophila) homolog 10 (Homo sapiens)
- gi|7512443|pir||JC7086 FZD10 protein - human (Homo sapiens)
- gi|5834488|dbj|BAA84093.1| (AB027464) Frizzled-10 [Homo sapiens] (Homo sapiens)
- gi|3323438|gb|AAC31121.1|_26:147 (AF017177) frizzled 8 protein; Xfz8 [Xenopus laevis] (Xenopus laevis)
- gi|6636325|gb|AAF20143.1|AF207665_1_1:111 (AF207665) secreted frizzled-related protein [Gallus gallus] (Gallus gallus)
- gi|6572469|emb|CAB63117.1|_30:151 (AJ251750) frizzled 4 protein [Xenopus laevis] (Xenopus laevis)
- gi|2337937|gb|AAB67062.1|_52:174 (U85945) FrzA [Bos taurus] (Bos taurus)
- gi|3869266|gb|AAC77361.1|_28:149 (AF033110) frizzled-8 [Xenopus laevis] (Xenopus laevis)
- gi|7294400|gb|AAF49746.1|_52:169 (AE003535) CG3646 gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|2415417|gb|AAB70793.1|_58:180 (AF017987) secreted apoptosis related protein 2 [Homo sapiens] (Homo sapiens)
- gi|8400732|ref|NP_003003.2|_57:179 secreted frizzled-related protein 1 (Homo sapiens)
- gi|2213819|gb|AAB61576.1| (AF001900) secreted frizzled-related protein [Homo sapiens] (Homo sapiens)
- gi|3033551|gb|AAC12877.1| (AF056087) secreted frizzled related protein [Homo sapiens] (Homo sapiens)
- gi|6679883|ref|NP_032082.1|_22:146 frizzled homolog 6 (Drosophila) (Mus musculus)
- gi|1151256|gb|AAC52431.1| (U43319) transmembrane receptor [Mus musculus] (Mus musculus)
- gi|6912384|ref|NP_036325.1|_43:164 frizzled (Drosophila) homolog 4 (Homo sapiens)
- gi|7522622|pir||JC7127 frizzled protein 4 - human (Homo sapiens)
- gi|6277266|dbj|BAA86286.1| (AB032417) WNT receptor Frizzled-4 [Homo sapiens] (Homo sapiens)
- gi|7340124|gb|AAF61096.1|AF224316_1_31:152 (AF224316) Frizzled-4 [Gallus gallus] (Gallus gallus)
- gi|6679881|ref|NP_032081.1|_43:164 frizzled homolog 4 (Drosophila) (Mus musculus)
- gi|1151254|gb|AAC52430.1| (U43317) transmembrane receptor [Mus musculus] (Mus musculus)
- gi|6007775|gb|AAF01036.1|AF183910_1_44:165 (AF183910) frizzled receptor 4 [Rattus norvegicus] (Rattus norvegicus)
- gi|6677895|ref|NP_033170.1|_40:150 stromal cell derived factor 5 (Mus musculus)
- gi|1946343|gb|AAC53146.1| (U88567) secreted frizzled related protein sFRP-2 [Mus musculus] (Mus musculus)
- gi|2415421|gb|AAB70795.1|_40:150 (AF017989) secreted apoptosis related protein 1 [Mus musculus] (Mus musculus)
- gi|1747302|dbj|BAA09053.1|_40:150 (D50462) SDF5 [Mus musculus] (Mus musculus)
- gi|7512442|pir||JE0174_40:150 frizzled protein-2 - human (Homo sapiens)
- gi|4503829|ref|NP_003459.1|_32:143 frizzled 5; Wnt receptor (Homo sapiens)
- gi|1151252|gb|AAC50385.1| (U43318) transmembrane receptor [Homo sapiens] (Homo sapiens)
- gi|4689161|gb|AAD27789.1|AF088850_1_38:159 (AF088850) frizzled-9 [Mus musculus] (Mus musculus)
- gi|4503835|ref|NP_003499.1|_37:158 frizzled 9 (Homo sapiens)
- gi|1906598|gb|AAC51174.1| (U82169) frizzled homolog [Homo sapiens] (Homo sapiens)
- gi|6746598|gb|AAF27642.1|AF218056_1_37:147 (AF218056) secreted frizzled-related protein-2 [Gallus gallus] (Gallus gallus)
- gi|1589780|gb|AAC47301.1|_26:136 (U63557) transmembrane receptor LIN-17 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|7105632|gb|AAF36028.1| (AC024201) C. elegans transmembrane receptor LIN-17 (GB:U63557); contains similarity to Pfam family PF01392 (Fz domain), score=241.6, E=1.1e-68, N=1 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|6539733|gb|AAF15998.1|_1:104 (AF153476) Frzb-1 [Gallus gallus] (Gallus gallus)
- gi|4503831|ref|NP_003497.1|_22:145 frizzled 6 (Homo sapiens)
- gi|7451363|pir||JE0164 frizzled-6 protein precursor - human (Homo sapiens)
- gi|3062803|dbj|BAA25686.1| (AB012911) Frizzled-6 [Homo sapiens] (Homo sapiens)
- gi|5305409|gb|AAD41637.1|AF072873_1 (AF072873) frizzled 6 [Homo sapiens] (Homo sapiens)
- gi|5729989|ref|NP_006578.1|_453:570 corin (Homo sapiens)
- gi|4884872|gb|AAD31850.1|AF133845_1 (AF133845) corin [Homo sapiens] (Homo sapiens)
- gi|8394057|ref|NP_058565.1|_521:639 corin (Mus musculus)
- gi|7513714|pir||JE0315 low-density lipoprotein receptor-related protein - mouse (Mus musculus)
- gi|3869145|dbj|BAA34371.1| (AB013874) Low Density Lipoprotein Receptor Related Protein 4 [Mus musculus] (Mus musculus)
- gi|7381173|gb|AAF61421.1|AF136184_1_26:133 (AF136184) putative wnt inhibitor frzb3 [Xenopus laevis] (Xenopus laevis)
- gi|3089551|gb|AAC15063.1|_27:134 (AF059570) secreted Xwnt8 inhibitor sizzled [Xenopus laevis] (Xenopus laevis)
- gi|7290800|gb|AAF46245.1|_45:169 (AE003439) CG4626 gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|7511690|pir||T37325_24:133 wingless protein receptor Cfz2 - Caenorhabditis elegans (Caenorhabditis elegans)
- gi|5931530|dbj|BAA84678.1| (AB026113) Cfz2 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|5042380|gb|AAB87503.2|_2:116 (AF033585) frizzled-9 protein [Mus musculus] (Mus musculus)
- gi|1151250|gb|AAC46993.1|_24:145 (U43316) transmembrane receptor [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|7331804|gb|AAF60492.1| (AC006736) C. elegans frizzled protein homolog precursor (GB:U43316); contains similarity to Pfam family PF01392 (Fz domain), score=182, E=9.2e-51, N-1 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|7331805|gb|AAF60493.1|_24:145 (AC006736) C. elegans frizzled protein homolog precursor (GB:U43316); contains similarity to Pfam family PF01392 (Fz domain), score=182, E=9.2e-51, N-1 [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|7512441|pir||JE0175_53:160 frezzled protein-1b - human (Homo sapiens)
- gi|4105677|gb|AAD02492.1|_54:162 (AF049908) frizzled-related protein; FrzA; Wnt-binding protein [Xenopus laevis] (Xenopus laevis)
- gi|6578963|gb|AAF18154.1|AF209200_1_29:146 (AF209200) frizzled receptor [Hydra vulgaris] (Hydra vulgaris)
- gi|1151180|gb|AAC52429.1|_26:142 (U43205) frizzled-3 [Mus musculus] (Mus musculus)
- gi|4506897|ref|NP_003006.1|_53:160 secreted frizzled-related protein 5 (Homo sapiens)
- gi|2415419|gb|AAB70794.1| (AF017988) secreted apoptosis related protein 3 [Homo sapiens] (Homo sapiens)
- gi|4583386|gb|AAD25052.1|AF117758_1 (AF117758) secreted frizzled-related protein 5 [Homo sapiens] (Homo sapiens)
- gi|4583384|gb|AAD25051.1|AF117757_1_51:158 (AF117757) secreted frizzled-related protein 5 [Bos taurus] (Bos taurus)
- gi|8393378|ref|NP_059108.1|_26:145 frizzled (Drosophila) homolog 3 (Homo sapiens)
- gi|7649449|emb|CAB89114.1| (AJ272427) frizzled homolog 3 [Homo sapiens] (Homo sapiens)
- gi|7670052|dbj|BAA94968.1| (AB039723) WNT receptor frizzled-3 [Homo sapiens] (Homo sapiens)
- gi|4583388|gb|AAD25053.1|AF117759_1_50:157 (AF117759) secreted frizzled-related protein 5 [Mus musculus] (Mus musculus)
- gi|2226372|gb|AAB61752.1|_44:151 (AF006508) crescent [Gallus gallus] (Gallus gallus)
- gi|7381171|gb|AAF61420.1|_38:145 (AF136183) putative wnt inhibitor frzb2 [Xenopus laevis] (Xenopus laevis)
- gi|7839501|gb|AAF70300.1|AF255340_1 (AF255340) Crescent [Xenopus laevis] (Xenopus laevis)
- gi|7839591|gb|AAF70340.1|AF260729_1 (AF260729) crescent [Xenopus laevis] (Xenopus laevis)
- gi|2440219|emb|CAA04977.1|_25:145 (AJ001754) fz3 [Xenopus laevis] (Xenopus laevis)
- gi|2415415|gb|AAB70792.1|_40:148 (AF017986) secreted apoptosis related protein 1 [Homo sapiens] (Homo sapiens)
- gi|2921088|gb|AAC04668.1|_44:161 (AF017637) carboxypeptidase Z [Rattus norvegicus] (Rattus norvegicus)
- gi|2921090|gb|AAC04669.1|_44:161 (AF017638) carboxypeptidase Z [Rattus norvegicus] (Rattus norvegicus)
- gi|7106481|dbj|BAA92184.1|_124:246 (AB031542) frizzled homolog [Ciona intestinalis] (Ciona intestinalis)
- gi|7290081|gb|AAF45547.1|_38:154 (AE003418) fz3 gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|5729989|ref|NP_006578.1|_137:248 corin (Homo sapiens)
- gi|4884872|gb|AAD31850.1|AF133845_1 (AF133845) corin [Homo sapiens] (Homo sapiens)
- gi|1167906|gb|AAC52903.1|_370:490 (U03715) alpha-1(XVIII) collagen [Mus musculus] (Mus musculus)
- gi|7446033|pir||B56101_370:490 collagen alpha 1(XVIII) chain precursor, long splice form - mouse (Mus musculus)
- gi|841240|gb|AAA91635.1|_370:490 (U19600) alpha 1 type XVIII collagen [Mus cookii] (Mus cookii)
- gi|618430|gb|AAC52179.1|_370:490 (U11637) alpha-1 type XVIII collagen precursor [Mus musculus] (Mus musculus)
- gi|8394057|ref|NP_058565.1|_204:317 corin (Mus musculus)
- gi|7513714|pir||JE0315 low-density lipoprotein receptor-related protein - mouse (Mus musculus)
- gi|3869145|dbj|BAA34371.1| (AB013874) Low Density Lipoprotein Receptor Related Protein 4 [Mus musculus] (Mus musculus)
- gi|7532831|gb|AAF63250.1|AF195242_1_38:154 (AF195242) FRIZZLED 3 [Drosophila melanogaster] (Drosophila melanogaster)
- gi|5931528|dbj|BAA84677.1|_38:154 (AB018565) Dfrizzled-3 [Drosophila melanogaster] (Drosophila melanogaster)
- gi|7500013|pir||T31690_2:94 hypothetical protein F27E11.3 - Caenorhabditis elegans (Caenorhabditis elegans)
- gi|2291116|gb|AAB65257.1| (AF016413) similar to the FRIZZLED-like transmembrane receptors [Caenorhabditis elegans] (Caenorhabditis elegans)
- gi|4503025|ref|NP_003643.1|_30:147 carboxypeptidase Z precursor (Homo sapiens)
- gi|2160714|gb|AAB58911.1| (U83411) carboxypeptidase Z precursor [Homo sapiens] (Homo sapiens)
- gi|1917009|gb|AAB51299.1|_5:95 (U91904) Fritz [Mesocricetus auratus] (Mesocricetus auratus)
- gi|7839499|gb|AAF70299.1|AF255339_1_43:121 (AF255339) secreted frizzled-related protein 2 [Xenopus laevis] (Xenopus laevis)
- gi|6981564|ref|NP_036939.1|_72:174 smoothened (Rattus norvegicus)
- gi|6226144|sp|P97698|SMO_RAT SMOOTHENED HOMOLOG PRECURSOR (SMO) (Rattus norvegicus)
- gi|1813878|gb|AAB41789.1| (U84402) smoothened [Rattus norvegicus] (Rattus norvegicus)
- gi|6226143|sp|P56726|SMO_MOUSE_72:174 SMOOTHENED HOMOLOG PRECURSOR (SMO) (Mus musculus)
- gi|7513827|pir||JC5539 Smoothened protein precursor - mouse (Mus musculus)
- gi|7290916|gb|AAF46357.1|_372:489 (AE003443) CG1632 gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|5032099|ref|NP_005622.1|_68:171 smoothened (Drosophila) homolog (Homo sapiens)
- gi|6226142|sp|Q99835|SMO_HUMAN SMOOTHENED HOMOLOG PRECURSOR (SMO) (Homo sapiens)
- gi|1813876|gb|AAB41788.1| (U84401) smoothened [Homo sapiens] (Homo sapiens)
- gi|4324955|gb|AAD17202.1| (AF114821) smoothened [Homo sapiens] (Homo sapiens)
- gi|6940763|gb|AAF31757.1| (AF120103) Gx protein [Homo sapiens] (Homo sapiens)
- gi|6226140|sp|O42224|SMO_CHICK_38:145 SMOOTHENED HOMOLOG PRECURSOR (SMO) (Gallus gallus)
- gi|2618975|gb|AAB84389.1| (AF019977) smoothened [Gallus gallus] (Gallus gallus)
- gi|7304194|gb|AAF59230.1|_759:871 (AE003840) CG2105 gene product [Drosophila melanogaster] (Drosophila melanogaster)
- gi|7511863|pir||T13484_17:99 frizzled protein homolog - fruit fly (Drosophila melanogaster) (Drosophila melanogaster)
- gi|3645951|emb|CAA20896.1| (AL031583) /prediction=(method:""genefinder"", version:""084"", score:""60.60"")~/match=(desc:""DFZ2"", species:""Drosophila melanogaster (Fruit fly)"", ranges:(query:5735..5932, target:SPTREMBL::Q94916:82..147, score:""117.00""), (query:6239..6445, ta> (Drosophila melanogaster)
- gi|7297269|gb|AAF52532.1|_313:422 (AE003618) CG6739 gene product [Drosophila melanogaster] (Drosophila melanogaster)

              10          20         30               40         50    
              |           |          |                |          |    
   1 AACEPVRIPLCKS..LPWEMTKMP.NHLHHSTQANAILA.....ME..QFEGLLGT.HCSPDLLF
   2 AACEPVRIPLCKS..LPWNMTKMP.NHLHHSTQANAILA.....ME..QFEGLLGT.HCSPDLLF
   3 AACEPVRIPLCKS..LPWNMTKMP.NHLHHSTQANAILA.....IE..QFEGLLGT.HCSPDLLF
   4 AACEPVRIPLCKS..LPWNMTKMP.NHLHHSTQANAILA.....IE..QFEGLLGT.HCSPDLLF
   5 AACEPVRIPLCKP..LPWNMTKMP.NHLHHSTQANAVLA.....ME..QFEGLLGT.NCSPDLLF
   6 AACEPVRIPLCKS..LPWNMTKMP.NHLHHSTQDNAILA.....IE..QFEGLLGT.HCSPDLLF
   7 AACEPVRIPLCKS..LPWNMTKMP.NHLHHSTQANAILA.....IE..QFEGLLGT.HCSPDLLF
   8 -SCEPIRIPMCKS..MPWNMTKMP.NHLHHSTQANAVLA.....IE..QFEGLLGT.QCSADLLF
   9 -PCEAVRIPMCRH..MPWNITRMP.NHLHHSTQENAILA.....IE..QYEELVDV.NCSSVLRF
  10 -PCEAVRIPMCRH..MPWNITRMP.NHLHHSTQENAILA.....IE..QYEELVDV.NCSSVLRF
  11 -PCEAVRIPMCRH..MPWNITRMP.NHLHHSTQENAILA.....IE..QYEELVDV.NCSAVLRF
  12 -PCEAVRIPMCRH..MPWNITRMP.NHLHHSTQENAILA.....IG..QYEELVDV.NCSSVLSF
  13 ASCEPVRIPMCKS..MPWNMTKMP.NHLHHSTQANAILA.....IE..QFEGLLTT.ECSQDLLF
  14 ASCEPVRIPMCKS..MPWNMTKMP.NHLHHSTQANAILA.....IE..QFEGLLTT.ECSQDLLF
  15 -PCEAVRIPMCRH..MPWNITRMP.NHLHHSTQENAILA.....IE..QYEELVDV.NCSSVLSF
  16 -RCEPITISICKN..IPYNMTIMP.NLIGHTKQEEAGLE.....VH..QFAPLVKI.GCSDDLQL
  17 -RCEPITISICKN..IPYNMTIMP.NLIGHTKQEEAGLE.....VH..QFAPLVKI.GCSDDLQL
  18 -RCEPITISICKN..IPYNMTIMP.NLIGHTKQEEAGLE.....VH..QFAPLVKI.GCSADLQL
  19 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  20 -RCEPITISICKN..IPYNMTIMP.NLIGHTKQEEAGLE.....VH..QFAPLVKI.GCSDDLQL
  21 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  22 GFCQPISIPLCTD..IAYNQTILP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  23 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  24 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  25 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  26 GFCQPISIPLCTD..IAYNQTILP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  27 GFCQPISIPLCTD..IAYNQTILP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  28 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSLELKF
  29 GYCQPISIPLCTD..MAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSAELKF
  30 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSSELRF
  31 GYCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSAELKF
  32 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  33 HVCQEISVPLCRG..IGYNYTYMP.NQFNHDNQDEAGLE.....VH..QFWPLVEI.QCSPDLRF
  34 GFCQPISIPLCTD..IAYNQTILP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSAELKF
  35 LACQEITVPLCKG..IGYNYTYMP.NQFNHDTQDEAGLE.....VH..QFWPLVEI.QCSPDLKF
  36 GYCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSAELKF
  37 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  38 GFCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELRF
  39 GYCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSAELKF
  40 GYCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSPELKF
  41 HVCQEISVPLCRG..IGYNYTYMP.NQFNHDNQDEAGLE.....VH..QFWPLVEI.QCSPDLRF
  42 GFCQPISIPLCTD..IAYNQTILP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSAELKF
  43 HVCQEISVPLCRG..IGYNYTYMP.NQFNHDNQDEAGLE.....VH..QFWPLVEI.QCSPDLRF
  44 GYCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSAELKF
  45 GYCQPISIPLCTD..IAYNQTIMP.NLLGHTNQEDAGLE.....VH..QFYPLVKV.QCSAELKF
  46 ITCQEIAVPLCKG..IGYNYTYMP.NQFNHDTQDEAGLE.....VH..QFWPLVEI.QCSPDLKF
  47 ITCQEIAVPLCKG..IGYNYTYMP.NQFNHDTQDEAGLE.....VH..QFWPLVEI.QCSPDLKF
  48 ITCQEIAVPLCKG..IGYNYTYMP.NQFNHDTQDEAGLE.....VH..QFWPLVEI.QCSPDLKF
  49 GRCQEIAIPLCKD..IGYNLTVMP.NLMGHEDQNEAAIK.....LH..EFAPLIEF.GCHSHLKF
  50 GRCQEIAIPLCKD..IGYNLTVMP.NLMGHEDQNEAAIK.....LH..EFAPLIEF.GCHSHLKF
  51 GRCQPIEIPMCKD..IGYNMTRMP.NLMGHENQREAAIQ.....LH..EFAPLVEY.GCHGHLKF
  52 GRCQAIEIPMCKD..IGYNMTRMP.NLMGHENQKEAAIQ.....LH..EFAPLVEY.GCHSHLKF
  53 RKCEHITIPMCKN..LDYNQTVFP.NLLGHTTQSEAGPA.....IA..QFNPLIKV.KCSEDIRL
  54 CVDIPVDLRLCHN..VGYKKMVLP.NLLEHETMAEVKQQ.....AS..SWVPLLNK.NCHMGTQV
  55 LRCEEITIPMCRG..IGYNMTSFP.NEMNHETQDEAGLE.....VH..QFWPLVEI.KCSPDLKF
  56 LRCEEITIPMCRG..IGYNMTSFP.NEMNHETQDEAGLE.....VH..QFWPLVEI.KCSPDLKF
  57 LRCEEITIPMCRG..IGYNMTSFP.NEMNHETQDEAGLE.....VH..QFWPLVEI.KCSPDLKF
  58 IVCEPITVPMCKG..IGYNHTYMP.NQFNHDNQDEVGLE.....VH..QFWPLVRI.HCSPDLLF
  59 -KCQPIEIPMCKD..IGYNMTRMP.NLMGHENQREAAIQ.....LH..EFAPLVEY.GCHGHLRF
  60 LSCQEITVPLCKD..IGYNYTYMP.NQFNHDTQDEAGME.....VH..QFWPLVVI.HCSPDLKF
  61 -------------..--WNMTKMP.NHLHHSTQANAVLA.....ME..QFEGLLGT.NCSPDLLF
  62 -SCDPIRITMCQN..LGYNVTKMP.NLVGHELQADAELQ.....LT..TFTPLIQY.GCSSQLQF
  63 CVDIPADLRLCHN..VGYKRMVLP.NLLEHETMAEVKQQ.....AS..SWVPLLNK.NCHIGTQV
  64 LSCQEITVPLCKD..IGYNYTYMP.NQFNHDTQDEAGME.....VH..QFWPLVVI.HCSPDLKF
  65 -RCEPITISICKN..IPYNMTIMP.NLIGHTKQEEAGLE.....VH..QFAPLVKI.GCSDDLQL
  66 CVDIPADLRLCHN..VGYKKMVLP.NLLEHETMAEVKQQ.....AS..SWVPLLNK.NCHAGTQV
  67 CVDIPADLRLCHN..VGYKKMVLP.NLLEHETMAEVKQQ.....AS..SWVPLLNK.NCHAGTQV
  68 FTCEPITVPRCMK..MTYNMTFFP.NLMGHYDQGIAAVE.....MG..HFLHLANL.ECSPNIEM
  69 RRCDPIRISMCQN..LGYNVTKMP.NLVGHELQTDAELQ.....LT..TFTPLIQY.GCSSQLQF
  70 RRCDAIRIAMCQN..LGYNVTKMP.NLVGHELQADAELQ.....LT..TFTPLIQY.GCSSQLQF
  71 RRCDPIRIAMCQN..LGYNVTKMP.NLVGHELQTDAELQ.....LT..TFTPLIQY.GCSSQLQF
  72 RRCDPIRIAMCQN..LGYNVTKMP.NLVGHELQTDAELQ.....LT..TFTPLIQY.GCSSQLQF
  73 CKPIPANLQLCHG..IEYQNMRLP.NLLGHETMKEVLEQ.....AG..AWIPLVMK.QCHPDTKK
  74 CKPIPANLQLCHG..IEYQNMRLP.NLLGHETMKEVLEQ.....AG..AWIPLVMK.QCHPDTKK
  75 CKPIPANLQLCHG..IEYQNMRLP.NLLGHETMKEVLEQ.....AG..AWIPLVMK.QCHPDTKK
  76 CKPIPANLQLCHG..IEYQNMRLP.NLLGHETMKEVLEQ.....AG..AWIPLVMK.QCHPDTKK
  77 -VCQEITVPMCRG..IGYNLTHMP.NQFNHDTQDEAGLE.....VH..QFWPLVEI.QCSPDLRF
  78 APCQAMEIPMCRG..IGYNLTRMP.NLLGHTSQGEAAAQ.....LA..EFSPLVQY.GCHSHLRF
  79 APCQAVEIPMCRG..IGYNLTRMP.NLLGHTSQGEAAAE.....LA..EFAPLVQY.GCHSHLRF
  80 CKPIPAPMLLCRG..IEYQSMRLP.NLLGHETVQEVLEQ.....AT..TWIPLVQK.QCHPDTRK
  81 GKCIPIDIELCKD..LPYNYTYFP.NTILHNDQHTLQTH.....TE..HFKPLMKT.KCHPHIHF
  82 -------------..---------.NHLHHSTQANAVLA.....ME..QFEGLLGT.NCSPDLLF
  83 FTCEPITVPRCMK..MAYNMTFFP.NLMGHYDQSIAAVE.....ME..HFLPLANL.ECSPNIET
  84 SQCEPITLELCMN..LPYNSTSYP.NYFGHRTQKEASIS.....WEssLFPALVQT.NCYKYLMF
  85 SQCEPITLELCMN..LLYNHTHYP.NYLGHRTQKEASIS.....WEssLFPALVQT.NCYKYLMF
  86 CVPIPKEMAMCND..VGYSEMRLP.NLLGHTNMAEVVPK.....SA..EWQNLLQT.GCHPYART
  87 CVTIPTEMAMCND..VGYSEMRLP.NLMGHTNMAEVVPK.....SA..EWQNLLQT.GCHPYART
  88 -QCETIRIEMCRK..IGYNETSMP.NLVGNEMQTDVEYT.....LQ..TFAPLIEY.DCSSQLKL
  89 -KCEQITIPLCKG..IGYNMTSFP.NSYGHEKQEEAGLE.....VH..QFYPLVEV.GCFQHLKF
  90 -------IPMCRG..IGYNLTRMP.NLLGHTPQGEAAAQ.....LA..EFSPLVQY.GCHSHLRF
  91 QRCQKVDHEMCND..LPYNLTSFP.NLVDEESWKDASES.....IL..TYKPLLSV.VCSEQLKF
  92 QRCQKVDHEMCND..LPYNLTSFP.NLVDEESWKDASES.....IL..TYKPLLSV.VCSEQLKF
  93 CLDIPADLPLCHT..VGYKRMRLP.NLLEHESLAEVKQQ.....AS..SWLPLLAK.RCHSDTQV
  94 CLEIPQDMTLCHG..VGYNKMVLP.NLLDSETMAEVKYQ.....AS..SWVPLLSK.KCHPSTQV
  95 CIPFAHHFQICNK..MPYNTTMFP.NLLEHRNPEEASLE.....VA..QFKPLVKV.GCSDDLEF
  96 FSCEPITLRMCQD..LPYNTTFMP.NLLNHYDQQTAALA.....ME..PFHPMVNL.DCSRDFRP
  97 CLDIPADLPLCHT..VGYKRMRLP.NLLEHESLAEVKQQ.....AS..SWLPLLAK.RCHSDTQV
  98 CLDIPADLPLCHT..VGYKRMRLP.NLLEHESLAEVKQQ.....AS..SWLPLLAK.RCHSDTQV
  99 FSCEPITLRMCQD..LPYNTTFMP.NLLNHYDQQTAALA.....ME..PFHPMVNL.DCSRDFRP
 100 CLDIPADLPLCHT..VGYKRMRLP.NLLEHESLAEVKQQ.....AS..SWLPLLAK.RCHSDTQV
 101 CTAIPRSMALCYD..IGYSEMRIP.NLLEHETMPEVIQQ.....SS..SWLPLLAR.ECHPDARI
 102 CMRIPKSMALCYD..IGYSEMRIP.NLLEHETMAEAIQQ.....SS..SWLPLLAR.ECHPDARI
 103 FACEPITLRMCQD..LPYNSTFMP.NLLNHYDQQTAALA.....ME..PFHPMVNL.ECSRDLRP
 104 CKPIPANLQLCHG..IEYQNMRLP.NLLGHETMKEVLEQ.....AG..AWIPLVMK.QCHPDTKK
 105 ATCVDLHLRTCAD..AAYNHTSFP.TPLEHRSWEAVEASpeytlLG..VLHFLLEG.QCNPDLRL
 106 ATCVDLHLRTCAD..AAYNHTSFP.TPLEHRSWEAVEASpeytlLG..VLHFLLEG.QCNPDLRL
 107 GVCEPIQVPMCID..IGYNFTDMSvSPSYIYDQKEAAQS.....VI..QFGPLTKT.KCAEEMKL
 108 LQCQPIAVSACQG..LGYNMTALP.NLAGHTNQLEAELQ.....IA..KLVPLIES.GCSRRARF
 109 SACMNITHSQCQM..LPYHATLTP.-LLSVVRNMEMEKF.....LK..FFTYLHRL.SCYQHIML
 110 CLPLPPTLTLCSR..LGIGHFWLP.NHLHHTDSVEVEAT.....VQ..AWGRFLHT.NCHPFLAW
 111 CLPLPPTLTLCSR..LGIGHFWLP.NHLHHTDSVEVEAT.....VQ..AWGRFLHT.NCHPFLAW
 112 CLPLPPTLTLCSR..LGIGHFWLP.NHLHHTDSVEVEAT.....VQ..AWGRFLHT.NCHPFLAW
 113 CLPLPPTLTLCSR..LGIGHFWLP.NHLHHTDSVEVEAT.....VQ..AWGRFLHT.NCHPFLAW
 114 STCMNITHSQCQI..LPYHSTLAP.-LLPIVKNMDMEKF.....LK..FFTYLHRL.SCYQHILL
 115 LQCQPIAVSACQG..LGYNMTALP.NLAGHTNQLEAELQ.....IA..KLVPLIES.GCSRRARF
 116 LQCQPIAVSACQG..LGYNMIALP.NLAGHTNQLEAELQ.....IA..KLVPLIES.GCSRRARF
 117 -------------..-----TSFP.NSYGHEKQEEAGLE.....VH..QFYPLVEV.GCFQHLKF
 118 ATCVDLQLRTCSD..AAYNHTTFP.NLLQHRSWEVVEASseyilLS..VLHQLLEG.QCNPDLRL
 119 -------------..---------.------------LX.....IX..QFEGLLXT.HCXGDLLF
 120 CKPIPATLVLCHD..IEYPNMRLP.NLLGHESMKEVLQQ.....AS..SWIPLVQK.QCHQDTKK
 121 AHCEPLRYNVCLGsaLPYGATTTL.LAGDSDSQEEAHSK.....LV..LWSGLRNApRCWAVIQP
 122 AHCEPLRYNVCLGsaLPYGATTTL.LAGDSDSQEEAHGK.....LV..LWSGLRNApRCWAVIQP
 123 RRCSPLELSYCRQ..VGYNITTYP.NLLGHASYEQLAED.....VI..VFRELVDG.ECHREAYD
 124 APCEPLRYNVCLGsvLPYGATSTL.LAGDSDSQEEAHGK.....LV..LWSGLRNApRCWAVIQP
 125 AACERLRFGSCLGsaLPYAHTSTL.LAADSGSQEEAHGK.....LL..LWSGLRNApRCWDVIQP
 126 GTCLPIIVRFCQGpqIPYNYTVFP.NYIGHFGQLETQTD.....LD..SYEALVDV.RCYELVSL
 127 -------------..---------.------------IP.....IA..KLVPLIES.GCSRRARF
 128 -GCQSTMLPMCQGv.LDYDLTFNR.EGAAPRD----AVS.....MA..AYDSLIRA.NCSVRAAE


          60           70         80         90       100         110  
          |            |          |          |         |           |  
   1 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARQGC.EPILIKYRHSWPESLAC..DELPVYDR
   2 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARQGC.EPILIKYRHSWPESLAC..DELPVYDR
   3 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARQGC.EPILIKYRHSWPESLAC..EELPVYDR
   4 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARQGC.EPILIKYRHSWPENLAC..EELPVYDR
   5 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARAGC.EPVLIRYRHAWPESLAC..DELPLYDR
   6 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARQGC.EPILIKYRHSWPENLAC..EELPVYDR
   7 FLCAMYAPICTI...DFQH.EPINPCKSVCERARQGC.EPILIKYRHSWPENLAC..EELPVYDR
   8 FLCAMYAPICTI...DFQH.DPIKPCKSVCERAKCGC.EPVMKRYNHTWPESLAC..EELPVYDR
   9 FLCAMYAPICTL...EFLH.DPIKPCKSVCQRARDDC.EPLMKMYNHSWPESLAC..DELPVYDR
  10 FLCAMYAPICTL...EFLH.DPIKPCKSVCQRARDDC.EPLMKMYNHSWPESLAC..DELPVYDR
  11 FFCAMYAPICTL...EFLH.DPIKPCKSVCQRARDDC.EPLMKMYNHSWPESLAC..DELPVYDR
  12 FLCAMYAPICTL...EFLH.DPIKPCKSVCQRARDDC.EPLMKMYNHSWPESLAC..DELPVYDR
  13 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARAGC.EPILIKYRHTWPESLAC..EELPVYDR
  14 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARAGC.EPILIKYRHTWPESLAC..EELPVYDR
  15 FLCAMYAPICTL...EFLH.DPIKPCKSVSQRARDDC.EPLMKMYNHSWPESLAC..DELPVYDR
  16 FLCSLYVPVCTI...--LE.RPIPPCRSLCESARV-C.EKLMKTYNFNWPENLEC..SKFPVHGG
  17 FLCSLYVPVCTI...--LE.RPIPPCRSLCESARV-C.EKLMKTYNFNWPENLEC..SKFPVHGG
  18 FLCSLYVPVCTI...--LE.RPIPPCRSLCESARV-C.ETLMKTYNFNWPENLEC..SKFPVHGG
  19 FLCSMYAPVCTV...--LE.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  20 FLCSLYVPVCTI...--LE.RPIPPCRSLCESARV-C.EKLMKTYNFNWPENLEC..SKFPVHGG
  21 FLCSMYAPVCTV...--LE.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  22 FLCSMYAPVCTV...--LD.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  23 FLCSMYAPVCTV...--LE.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  24 FLCSMYAPVCTV...--LE.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  25 FLCSMYAPVCTV...--LE.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  26 FLCSMYAPVCTV...--LD.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  27 FLCSMYAPVCTV...--LD.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  28 FLCSMYAPVCTV...--LE.QAIPPCRSICERARQGC.EALMNKFGFQWPERLRC..ENFPRHGA
  29 FLCSMYAPVCTV...--LE.QALPPCRSLCERARQGC.EALMNKFGFQWPDTLKC..EKFPVHGA
  30 FLCSMYAPVCTV...--LE.QAIPPCRSICERARHGC.EALMNKFGFQWPERLRC..ENFPRHGA
  31 FLCSMYAPVCTV...--LE.QALPPCRSLCERARQGC.EALMNKFGFQWPDTLRC..EKFPVHGA
  32 FLCSMYAPVCTV...--LE.QAIPPCRSICERARQGC.EALMNKFGFQWPERLRC..EHFPRHGA
  33 FLCSMYTPICLE...DY-K.KPLPPCRSVCERAKAGC.APLMRQYGFPWPDRMRC..DLLPVQGD
  34 FLCSMYAPVCTV...--LE.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  35 FLCSMYTPICLE...DY-K.KPLPPCRSVCERAKAGC.APLMRQYGFAWPDRMRC..DRLPEQGN
  36 FLCSMYAPVCTV...--LE.QALPPCRSLCERARQGC.EALMNKFGFQWPDTLKC..EKFPVHGA
  37 FLCSMYAPVCTV...--LE.QAIPPCRSICERARQGC.EALMNKFGFQWPERLRC..EHFPRHGA
  38 FLCSMYAPVCTV...--LE.QAIPPCRSICERARQGC.EALMNKFGFQWPERLRC..EHFPRHGA
  39 FLCSMYAPVCTV...--LE.QALPPCRSLCERARQGC.EALMNKFGFQWPDTLKC..EKFPVHGA
  40 FLCSIYAPVCTV...--LE.QALPPCRSLCDRARQGC.EALMNKFGFQWPESLRC..EKFPINGA
  41 FLCSMYTPICLE...DY-K.KPLPPCRSVCERAKAGC.APLMRQYGFPWPDRMRC..DLLPVQGD
  42 FLCSMYAPVCTV...--LE.QAIPPCRSLCERARQGC.EALMNKFGFQWPERLRC..ENFPVHGA
  43 FLCSMYTPICLE...DY-K.KPLPPCRSVCERAKAGC.APLMRQYGFPWPDRMRC..DLLPVQGD
  44 FLCSMYAPVCTV...--LE.QALPPCRSLCERA-QGC.EALMNKFGFQWPDTLKC..EKFPVHGR
  45 FLCSMYAPVCTV...--LE.QALPPCRSLCERA-QGC.EALMNKFGFQWPDTLKC..EKFPVHGA
  46 FLCSMYTPICLE...DY-K.KPLPPCRSVCERAKAGC.APLMRQYGFPWPDRMRC..DLLPVQGA
  47 FLCSMYTPICLE...DY-K.KPLPPCRSVCERAKAGC.APLMRQYGFPWPDRMRC..DLLPVQGA
  48 FLCSMYTPICLE...DY-K.KPLPPCRSVCERAKAGC.APLMRQYGFPWPDRMRC..DLLPVQGA
  49 FLCSLYAPMCTE...QV-S.TPIPACRVMCEQARQKC.SPIMEQFNFHWPESLDC..SRLPNKND
  50 FLCSLYAPMCTE...QV-S.TPIPACRVMCEQARQKC.SPIMEQFNFHWPESLDC..SRLPNKND
  51 FLCSLYAPMCTE...QV-S.TPIPACRVMCEQARLKC.SPIMEQFNFKWPDSLDC..SKLPNKND
  52 FLCSLYAPMCTE...QV-S.TPIPACRVMCEQARLKC.SPIMEQFNFKWPDSLDC..SKLPNKND
  53 FLCTVYAPVCTV...--LE.KPIQPCRELCLSAKNGC.ESLMKKFGFQWPDQLDC..NKFPVTD-
  54 FLCSLFAPVCL-...---D.RPIYPCRWLCEAVRDSC.EPVMQFFGFYWPEMLKC..DKFPEGDV
  55 FLCSMYTPICLE...DY-H.KPLPVCRSVCERARSGC.APIMQQYSFEWPERMAC..EHLPLHGD
  56 FLCSMYTPICLE...DY-H.KPLPVCRSVCERARSGC.APIMQQYSFEWPERMAC..EHLPLHGD
  57 FLCSMYTPICLE...DY-H.KPLPVCRSVCERARSGC.APIMQQYSFEWPERMAC..EHLPLHGD
  58 FLCSMYTPICLQ...DY-K.KPLPPCRSVCERAKRGC.SPLMIQYGFEWPERMSC..EQLPMLGD
  59 FLCSLYAPMCTE...QV-S.TPIPACRVMCEQARLKC.SPIMEQFNFKWPDSLDC..RKLPNKND
  60 FLCSMYTPICLE...DY-K.KPLPPCRSVCERARAGC.APLMRQYGFAWPDRMRC..DRLPEQGN
  61 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARAGC.EPVLIRYRHAWPESLAC..DELPLYDR
  62 FLCSVYVPMCTE...KI-N.IPIGPCGGMCLSVKRRC.EPVLKEFGFAWPESLNC..SKFPPQND
  63 FLCSLFAPVCL-...---D.RPIYPCRWLCEAVRDSC.EPVMQFFGFYWPEMLKC..DKFPEGDV
  64 FLCSMYTPICLE...DY-K.KPLPPCRSVCERARAGC.APLMRQYGFAWPDRMRC..DRLPEQSN
  65 FLCSLYVPVCTI...--LE.RPIPPCRSLCESARV-C.EKLMKTYNFNWPENLEC..SKFPVHGG
  66 FLCSLFAPVCL-...---D.RPIYPCRWLCEAVRDSC.EPVMQFFGFYWPEMLKC..DKFPEGDV
  67 FLCSLFAPVCL-...---D.RPIYPCRWLCEAVRDSC.EPVMQFFGFYWPEMLKC..DKFPEGDV
  68 FLCQAFIPTCTE...--QI.HVVLPCRKLCEKIVSDC.KKLMDTFGIRWPEELEC..NRLPHCDD
  69 FLCSVYVPMCTE...KI-N.IPIGPCGGMCLSVKRRC.EPVLKEFGFAWPESLNC..SKFPPQND
  70 FLCSVYVPMCTE...KI-N.IPIGPCGGMCLSVKRRC.EPVLKEFGFAWPDSLNC..SKFPPQND
  71 FLCSVYVPMCTE...KI-N.IPIGPCGGMCLSVKRRC.EPVLREFGFAWPDTLNC..SKFPPQND
  72 FLCSVYVPMCTE...KI-N.IPIGPCGGMCLSVKRRC.EPVLKEFGFAWPDSLNC..SKFPPQND
  73 FLCSLFAPVCLD...DL-D.ETIQPCHSLCVQVKDRC.APVMSAFGFPWPDMLEC..DRFPQDND
  74 FLCSLFAPVCLD...DL-D.ETIQPCHSLCVQVKDRC.APVMSAFGFPWPDMLEC..DRFPQDND
  75 FLCSLFAPVCLD...DL-D.ETIQPCHSLCMQVKDRC.APVMSAFGFPWPDMLEC..DRFPQDND
  76 FLCSLFAPVCLD...DL-D.ETIQPCHSLCVQVKDRC.APVMSAFGFPWPDMLEC..DRFPQDND
  77 FLCTMYTPICLP...DY-H.KPLPPCRSVCERAKAGC.SPLMRQYGFAWPERMSC..DRLPVLGR
  78 FLCSLYAPMCTD...QV-S.TPIPACRPMCEQARLRC.APIMEQFNFGWPDSLDC..ARLPTRND
  79 FLCSLYAPMCTD...QV-S.TPIPACRPMCEQARLRC.APIMEQFNFGWPDSLDC..ARLPTRND
  80 FLCSLFAPVCID...DL-D.EIIQPCHSLCEEVKESC.APVMSAFGFPWPDMLDC..SRFPKDND
  81 FICSVFAPMCPI...GM-P.QAVTSCKSVCEQVKADC.FSILEEFGIGWPEPLNC..AQFPDPPE
  82 FLCAMYAPICTI...DFQH.EPIKPCKSVCERARAGC.EPVLIRYRHAWPESLAC..DELPLYDR
  83 FLCKAFVPTCIE...--QI.HVVPPCRKLCEKVYSDC.KKLIDTFGIRWPEELEC..DRLQYCDE
  84 FSCTILVPKCDV...NT-G.ERIPPCRALCEHSKERC.ESVLGIVGLQWPEDTDC..SQFPEENS
  85 FACTILVPKCDV...NT-G.QRIPPCRLLCEHSKERC.ESVLGIVGLQWPEDTDC..NQFPEESS
  86 FLCSLFAPVCL-...---D.TFIQPCRSMCVAVRNSC.APVLACHGHSWPESLDC..DRFPAGED
  87 FLCSLFAPVCL-...---D.TFIQPCRSMCVAVRDSC.APVLACHGHSWPESLDC..DRFPAGED
  88 FLCAAYVPMCTP...KAPV.HAIGPCRSLCESVRIRC.HPVLQGFGFPWPPALDC..DKFPRENN
  89 FLCTMYTPICQE...NY-D.KPILPCMELCVEARSKC.SPIMAKYGFRWPETLSC..EALPKMSD
  90 FLCSLYAPMCTD...QV-S.TPIPACRPMCEQARLRC.APIMEQFNFGWPDSLDC..ARLPTRND
  91 FLCSVYFPMCNE...KL-A.NPIGPCRPLCLSVQEKC.LPVLESFGFKWPDVIRC..DKFPLENN
  92 FLCSVYFPMCNE...KL-A.NPIGPCRPLCLSVQEKC.LPVLESFGFKWPDVIRC..DKFPLENN
  93 FLCSLFAPVCL-...---D.RPIYPCRSLCEAVRAGC.APLMEAYGFPWPEMLHC..HKFPLDND
  94 FLCSLFAPLCL-...---D.RPVYPCRRLCESVRDAC.EPVMQYFGFHWPEMLRC..EQYPTEED
  95 FLCSVYAPVCLN...---H.GPLPPCKPLCERARSGC.ISIMQKFGFIWPENIRC..ERYPDSTP
  96 FLCALYAPICME...--YG.RVTLPCRRLCQRAYSEC.SKLMEMFGVPWPEDMEC..SRFPDCDE
  97 FLCSLFAPVCL-...---D.RPIYPCRSLCEAVRAGC.APLMEAYGFPWPEMLHC..HKFPLDND
  98 FLCSLFAPVCL-...---D.RPIYPCRSLCEAVRAGC.APLMEAYGFPWPEMLHC..HKFPLDND
  99 FLCALYAPICME...--YG.RVTLPCRRLCQRAYSEC.SKLMEMFGVPWPEDMEC..SRFPDCDE
 100 FLCSLFAPVCL-...---D.RPIYPCRSLCEAARAGC.APLMEAYGFPWPEMLHC..HKFPLDND
 101 FLCSLFAPICL-...---D.RLIYPCRSLCEAVKRSC.APVMACYGYPWPEILNC..NKFPADHE
 102 FLCSLFAPICF-...---D.RYIFPCRSLCEAVRSSC.APIMACYGYPWPEILKC..DKFPEDHG
 103 FLCALYTPVCME...--YG.RMTLPCRKLCQRAYNEC.FKLMEMFGVPWPEEMEC..SRFPDCDE
 104 FLCSLFAPVCLD...DL-D.ETIQPCHSRCVQVKDRC.APVMSAF--PWPDMLEC..DRFPQDND
 105 LGCSVLAPRCQG...---G.HTQRPCRRVCEGLREAC.QPAFDAIDMAWPYFLDC..TQYFAPEE
 106 LGCSVLAPRCQG...---G.HTQRPCRRVCEGLREAC.QPAFDAIDMAWPYFLDC..TQYFAPEE
 107 LVCSVYTPICIP...GY-P.GFLPPCRFICEAAKAGC.EPILKKYDRTWPNLFDC..KQFPDSQG
 108 LLCSSLFPLCTP...DV-P.RPVAACKLLCETVRGECmENAPPELMELWPSFLNC..DGLPQPEK
 109 FGCTLAFPECII...DGDDsHGLLPCRSFCEAAKEGC.ESVLGMVNYSWPDFLRC..SQFRNQTE
 110 FFCLLLAPSCGP...GP-P.PPLPPCRQFCEALEDEC.WNYLAGDRLP----VVC..ASLPSQED
 111 FFCLLLAPSCGP...GP-P.PPLPPCRQFCEALEDEC.WNYLAGDRLP----VVC..ASLPSQED
 112 FFCLLLAPSCGP...GP-P.PPLPPCRQFCEALEDEC.WNYLAGDRLP----VVC..ASLPSQED
 113 FFCLLLAPSCGP...GP-P.PPLPPCRQFCEALEDEC.WNYLAGDRLP----VVC..ASLPSQED
 114 FGCSLAFPECVV...DGDDrHGLLPCRSFCEAAKEGC.ESVLGMVNSSWPDSLRC..SQFRDHTE
 115 LLCSSLFPLCTP...DV-P.RPVAACKLLCETVRGECmENAPPELMELWPSFLNC..DGLPQPEK
 116 LLCSSLFPLCTP...DV-P.RPVAACKLLCETVRGECmENAPPELMELWPSFLNC..DGLPQPEK
 117 FLCTMYTPICQE...NY-D.KPILPCMELCVEARSKC.SPIMAKYGFRWPETLSC..EALPKMSD
 118 LGCAVLAPRCEG...---G.WVRRPCRHICEGLREVC.QPAFDAIDMAWPYFLDC..HRYFTRED
 119 FLCAMYAPICTX...DFQR.EPIKPCKSVCERARQGC.EPILIKYRHSWPESLAC..EELPVYDR
 120 FLCSLFAPVCID...DL-D.ETIKPCRSLC-------.-----------------..--------
 121 LLCAVYMPKCEN...---D.RVELPSRTLCQATRGPC.AIVERERG--WPDFLRC..T-------
 122 LLCAVYMPKCEN...---D.RVELPSRTLCQATRGPC.AIVERERG--WPDFLRC..T-------
 123 FVCRLLQPPCDThgsDLQP.TPGQICREYCESFMAGC.GGRLPQ---RFRQFFDC..ERFPESTG
 124 LLCAVYMPKCEN...---D.RVELPSRTLCQATRGPC.AIVERERG--WPDFLRCtp--------
 125 LLCAVYMPKCED...---G.QVELPSQTLCQATRAPC.TIVERERG--WPDFLKCtpDRFP----
 126 FLCTLFVPKCGQ...--SG.ATVPPCKTLCTETMRRC.GFFFDVFGLSLPEYLNC..KLFKDFPS
 127 LLCSSLFPLCTP...DV-P.RPVAACKLLCETVRGECmENAPPELMELWPSFLNC..DGLPQPEK
 128 FICGALEPECRP...LH-I.GQLPPCRRICKAILEAC.SIPIYNSDV-LGELFDC..NLYPDAHE


           120        
            |        
   1 GVCISPEAIVTADGAD
   2 GVCISPEAIVTAD---
   3 GVCISPEAIVTAD---
   4 GVCISPEAIVTAD---
   5 GVCISPEAIVTAEG--
   6 GVCISPEAIVTAD---
   7 GVCISPEAIVTAD---
   8 GVCISPEAIVKAEGP-
   9 GVCISPEAIVTDLPE-
  10 GVCISPEAIVTDLPE-
  11 GVCISPEAIVTDLPE-
  12 GVCISPEAIVTDLPE-
  13 GVCISPEAIV------
  14 GVCISPEAIV------
  15 GVCISPEAIVTDLPE-
  16 EDLCVAENTT------
  17 EDLCVAENTT------
  18 EDLCVAENTT------
  19 GEICVGQNTSDNS---
  20 EDLCVAENTT------
  21 GEICVGQNTSDNS---
  22 GEICVGQNTSDG----
  23 GEICVGQNTSDNS---
  24 GEICVGQNTSDNS---
  25 GEICVGQNTSDNS---
  26 GEICVGQNTSDG----
  27 GEICVGQNTSDG----
  28 EQICVGQNHSEDG---
  29 GELCVGQNTSDK----
  30 EQICVGQNHSEDGG--
  31 GELCVGQNASER----
  32 EQICVGQNHSEDG---
  33 PNTLCMDYNRT-----
  34 GEICVGQNTSD-----
  35 PDTLCMDYNRT-----
  36 GELCVGQNTSDK----
  37 EQICVGQNHSEDG---
  38 EQICVGQNHSEDG---
  39 GELCVGQNTSDK----
  40 GELCVGQNTTES----
  41 PNTLCMDYNRT-----
  42 GEICVGQNTSD-----
  43 PNTLCMDYNRT-----
  44 GELCVGQNTSDK----
  45 GELCVGQNTSDK----
  46 PDTLCMDYNRT-----
  47 PDTLCMDYNRT-----
  48 PDTLCMDYNRT-----
  49 PNYLCMEAPNNGT---
  50 PNYLCMEAPNNGT---
  51 PNYLCMEAPNNGSD--
  52 PNYLCMEAPNNGT---
  53 ----------------
  54 CIAMTPPNTTEASKP-
  55 PDNLCMEQP-------
  56 PDNLCMEQP-------
  57 PDNLCMEQP-------
  58 TDRLCMDRN-------
  59 PNYLCMEAPNNGSD--
  60 PDTLCMDYYNR-----
  61 GVCISPEAIVTAEG--
  62 HNHMCMEGPGDD----
  63 CIAMTPPNATEASKP-
  64 PDTLCMDYYNR-----
  65 EDLCVAENTT------
  66 CIAMTPPNPTEASKP-
  67 CIAMTPPNATEASKP-
  68 TVPVTSHPHTELSGP-
  69 HNHMCMEGPGD-----
  70 HNHMCMEGPGD-----
  71 HNHMCMEGPGD-----
  72 HNHMCMEGPGD-----
  73 ----------------
  74 ----------------
  75 ----------------
  76 ----------------
  77 DA--------------
  78 PHALCMEAPEN-----
  79 PHALCMEAPEN-----
  80 ----------------
  81 ----------------
  82 GVCISPEAIVTAEG--
  83 TVPVTFDPHTEFLG--
  84 DNQTC-----------
  85 DNQTCL----------
  86 ----------------
  87 ----------------
  88 HETMCMEGPGELHQ--
  89 ----------------
  90 PHALCMEAPEN-----
  91 REKMCMKGPNE-----
  92 REKMCMKGPNE-----
  93 ----------------
  94 V---------------
  95 NALCIDNAE-------
  96 PYPRLVD---------
  97 ----------------
  98 ----------------
  99 PYPRLVDLNL------
 100 ----------------
 101 ----------------
 102 ----------------
 103 PYPRIVDISLS-----
 104 ----------------
 105 EGCY------------
 106 EGCY------------
 107 KNPPCLHFNRS-----
 108 HELCM-----------
 109 ----------------
 110 GYCVFIGPAAENVA--
 111 GYCVFIGPAAENVA--
 112 GYCVFIGPAAENVA--
 113 GYCVFIGPAAENVA--
 114 TN--------------
 115 HELCM-----------
 116 HELCM-----------
 117 ----------------
 118 EGCY------------
 119 GVCISPEAIVTAD---
 120 ----------------
 121 ----------------
 122 ----------------
 123 TQSCHQ----------
 124 ----------------
 125 ----------------
 126 S---------------
 127 HELCM-----------
 128 SHKC------------