Citations (SAM, SAM-T99, HMMs)
10 20 30 40 50
| | | | |
1 AAGTAKGHNPTEFPT...IYDASSAPTAA.....NTTVGIITIGGVSQTLQDLQQF.....TSAN
2 AAGTAKGHNPTEFPT...IYDASSAPTAA.....NTTVGIITIGGVSQTLQDLQQF.....TSAN
3 ------------GNF...AHQASVARVVGqqg..RGRAGIE-------ASLDVQYL.....MSAG
4 ------------GNF...AHQASVARVVGqqg..RGRAGIE-------ASLDVQYL.....MSAG
5 ------------GNF...AHQASVARVVGqqg..RGRAGIE-------ASLDVEYL.....MSAG
6 -------------SF...THQASVAKVVGkqg..RGRAGIE-------ASLDVEYL.....MSAG
7 -------------SF...THQASVAKVVGkqg..RGRAGIE-------ASLDVEYL.....MSAG
8 WATAIQQYNPIPKIA...SISYGWAEVEQce6nsCSTLGIDSVVYVARSNVELQKVg10vsSGDD
9 PAVTTQPFNPTVDVLplyGIDTSDSNRGA.....GQVIGIIDAYGASTAESDLAAF.....SRAN
10 --NATFSMNSARDTL...GHGTHTASTAA.....GNYVNGA-------SYFGYGKG.....TARG
11 AAAAVAAHHPQDFAA...IYGGSSLPAAT.....NTAVGIITWGSITQTVTDLNSF.....TSGA
12 AAGTAKGHNPTEFPT...IYDASSAPTAA.....NTTVGIITIGGVSQTLQDLQQF.....TSAN
13 ---------------...-----------.....----------------------.....----
14 ---------------...-------PVTG.....NSSVGVIEFEDQNFAPSDLSDF.....ATSF
15 --DYVDNDNTSDDGN...GHGTHCAGITGalt..NNSVGIA---------------.....---G
16 --DYVDNDNTSDDGN...GHGTHCAGITGalt..NNSVGIA---------------.....---G
17 ----VDNDSTPQNGN...GHGTHCAGIAAavt..NNSTGIA---------------.....---G
18 ----VDNDSTPQNGN...GHGTHCAGIAAavt..NNSTGIA---------------.....---G
19 ---FIDRDNNPMDLN...GHGTHVAGTVAadt..NNGIGVA---------------.....---G
20 ----VDNDYDPMDLN...NHGTHVAGIAAaet..NNATGIA---------------.....---G
21 ----VDNDYDPMDLN...NHGTHVAGIAAaet..NNATGIA---------------.....---G
22 ------------NNN...AHGTHVAGTIAai...ANNEGVV---------------.....---G
23 -------------NN...AHGTHVAGTIAai...ANNEGVK---------------.....---G
24 --------YQLNDVS...HHGTHVAGTVFaqy..GAGTGASGL----QSGMDA--N.....GVGG
25 WGKTIPAGDADEDGN...GHGTHCSGTIA.....GKKYGVA---------------.....----
26 WGKTIPAGDADEDGN...GHGTHCSGTIA.....GKKYGVA---------------.....----
27 ---------TARDGN...GHGTHCSGTIG.....SKTYGVA---------------.....----
28 ---------TARDGN...GHGTHCSGTIG.....SKTYGVA---------------.....----
29 ---------GTTDGH...GHGTHCAGTIG.....SKTYGVA---------------.....----
30 ---------QNRDGH...GHGTHCAGTIG.....SRSYGVA---------------.....----
31 ---------QNTDGH...GHGTHCAGTIG.....SKTYGVA---------------.....----
32 ---------QNTDGN...GHGTHCAGTIG.....SKTYGVA---------------.....----
33 -----------SDRN...GHGTHVAGTIG.....SKKYGVA---------------.....----
34 --------GQDTDGN...GHGTHVAGTVG.....GTTYGVA---------------.....----
35 ---------------...-----------.....----------------------.....----
36 ---------------...-----------.....----------------------.....----
37 ---FVDNDNDATDCN...GHGTHVAGTIG.....GGEYGVA---------------.....----
38 ---------QHVDSV...GHGTHVAGTIG.....GETYGVS---------------.....----
39 -------GGSHVDSI...GHGTHVAGTIG.....GKTTGVA---------------.....----
40 -------GGSHVDSI...GHGTHVAGTIG.....GKTYGVA---------------.....----
41 -------GGSHVDSI...GHGTHVAGTIG.....GKTYGVA---------------.....----
42 ----------NADLL...GHGTHVAGTVG.....GKTYGVD---------------.....----
43 ---------SNVDDN...GHGTHVAGTIG.....SRTYGVA---------------.....----
44 --------SNYQDRN...GHGTHVTGTVAai...DNDIGVI---------------.....---G
45 -----QPGDERTDHE...GHGTGMAALIAgtgkhGSKSGAY---------------.....---G
46 -----------RSWA...RHGTAMAGIIAgh6gsGDAEGVM---------------.....---G
47 ------------GGV...GHGTAVAGIAT.....----------------------.....---Q
48 --------EEVADRH...GHGTHVTSTVG.....GSGAASD--------------G.....KEKG
49 --FVDNDYDPKETPT...GDPRGEATDHG.....THVAGTVAANGTIK--------.....---G
50 --GECGIFSAARDSS...WHGTHVAGTIAeat..GNAIGGA---------------.....---G
51 ---------PAASSS...WHGTHVAGTVAavt..NNTTGVA---------------.....---G
52 CGGYPDPRREKKFST...WHGSHVAGTIAavt..NNGVGVA---------------.....---G
53 CGGYPDPRREKRFST...WHGSHVAGTIAavt..NNGVGVA---------------.....---G
54 -----------HDTT...DHGTHTAGLLV.....GSKVGVA---------------.....----
55 ---------------...-HGTHVAGIAE.....ANMPGWK---------------.....-MQG
56 ----TGSINDIDDKK...GHGTAVAGQIAan...----------GQIF--------.....---G
57 -------DNQVDENI...EHGTAVTSTIAaa...RDGRGVV---------------.....---G
58 -GATTPINNSCTDRN...GHGTHVAGTALadgg.SDQAGIY---------------.....---G
59 -GATTPINNSCTDRN...GHGTHVAGTALadgg.SDQAGIY---------------.....---G
60 -----FTDNSCTDRQ...GHGTHVAGSALang..GTGSGVY---------------.....---G
61 --GTTYTNNSCTDRQ...GHGTHVAGSALadg..GTGNGVY---------------.....---G
62 ------------NDQ...IVDNGCGEMHG.....QHVAGIAGANGQVK--------.....---G
63 ------DPTPTDPDT...GHGTSVSGIIAav...DNAIGTK---------------.....---G
64 ------------NND...SHGTHVTGTMGaa...RDGVGMH---------------.....---G
65 ------------NND...SHGTHVTGTMGaa...RDGVGMH---------------.....---G
66 ------------FDD...YHGTRCAGEIAavk..NDVCGI----------------.....---G
67 ------------KDD...YHGTRCAGEIAafr..NDICGV----------------.....---G
68 -----------TWFN...SHGTRCAGEVSa....AKDNGVC---------------.....-GVG
69 -----------TWFN...SHGTRCAGEVSa....AKDNGVC---------------.....-GVG
70 -----------TWFN...SHGTRCAGEVSa....AKDNGVC---------------.....-GVG
71 -----------TWFN...SHGTRCAGEVSa....AKDNGVC---------------.....-GVG
72 ------------FNF...TLAYERGYTGG.....GSNIAIEGVPESFVNVSDIYSF.....WQLY
60 70 80 90 100
| | | | |
1 GLAS..VNTQT.....IQTGSSNGD.YSDDQQG..QGEWDLDSQSIVGSAGGAV..QQLLFYMA.
2 GLAS..VNTQT.....IQTGSSNGD.YSDDQQG..QGEWDLDSQSIVGSAGGAV..QQLLFYMA.
3 ANIS..TW---.....--VYSSPGR.HE-----..--------------GQEPF..LQWLMLLS.
4 ANIS..TW---.....--VYSSPGR.HE-----..--------------GQEPF..LQWLMLLS.
5 ANIS..TW---.....--VYSSPGR.HE-----..--------------SQEPF..LQWLLLLS.
6 ANIS..TW---.....--VYSSPGR.HE-----..--------------AQEPF..LQWLLLLS.
7 ANIS..TW---.....--VYSSPGR.HE-----..--------------AQEPF..LQWLLLLS.
8 GAPS..FG-AA.....SGNCPIDGT.KQYCPLG..GCNHKSSQCPMITIMESNG..TQCFFPMGs
9 GLPA..ANFQK.....VDQNGGTNY.PKDDPDDasGDGWGVETALDLQIAHAVApaAKLILCTA.
10 IAPR..ARVAV.....YKVTWPEGR.YT-----..-------------------..--------.
11 GLAT..VNSTI.....TKVGS--GT.FANDPDS..NGEWSLDSQDIVGIAGGVK..QLIFYTSAn
12 GLAS..VNTQT.....IQTGSSNGD.YSDDQQG..QGEWDLDSQSIVGSAGGAV..QQLLFYMA.
13 ----..-----.....---------.-------..-------------------..--------.
14 SVPI..TPLTD.....NHIIGSNDP.TS----P..QIEATLDIQYILG------..VLLVQLDG.
15 VAPQ..TSIYA.....VRVLDNQGS.GT-----..-------------------..--------.
16 VAPQ..TSIYA.....VRVLDNQGS.GT-----..-------------------..--------.
17 TAPK..ASILA.....VRVLDNSGS.GT-----..-------------------..--------.
18 TAPK..ASILA.....VRVLDNSGS.GT-----..-------------------..--------.
19 MAPD..TKILA.....VRVLDANGS.GS-----..-------------------..--------.
20 MAPN..TRILA.....VRALDRNGS.GT-----..-------------------..--------.
21 MAPN..TRILA.....VRALDRNGS.GT-----..-------------------..--------.
22 VMPNqnANIHV.....INVFNEAGW.GY-----..-------------------..--------.
23 LLPNqnVNLHI.....VKVFNESGW.GY-----..-------------------..--------.
24 VASG..VNLYM.....ARVLGDDGS.GS-----..-------------------..--------.
25 --KK..ANVYA.....VKVLRSNGS.GT-----..----MADVVKGVEFAATSH..VEQVLRAK.
26 --KK..ANVYA.....VKVLRSNGS.GT-----..----MADVVKGVEFAATSH..VEQVLRAK.
27 --KK..VSIFG.....VKVLDDNGS.GS-----..-------------------..--------.
28 --KK..VSIFG.....VKVLDDNGS.GS-----..-------------------..--------.
29 --KK..ASILG.....VKVLEDSGS.GS-----..-------------------..--------.
30 --KN..AKLFA.....VKVLDDQGS.GS-----..-------------------..--------.
31 --KK..AKLYG.....VKVLDNQGS.GS-----..-------------------..--------.
32 --KK..TKIYG.....VKVLDNSGS.GS-----..-------------------..--------.
33 --KK..TKILG.....IKVLSDQGS.GD-----..-------------------..--------.
34 --KK..TSLFA.....VKVLDANGQ.GS-----..-------------------..--------.
35 ----..-----.....---------.-------..-------------------..--------.
36 ----..-----.....---------.-------..-------------------..--------.
37 --KN..VNIVG.....VRVLGCNGS.GS-----..-------------------..--------.
38 --KK..ANLLS.....VKVFQGESS.STSIILD..GFNWAANDIVSKGR-----..--------.
39 --KK..TNLLS.....VKVFQGESS.STSIILD..GFNWAVNDIVSKGRTKKA-..--------.
40 --KK..TNLLS.....VKVFQGESS.STSIILD..GFNWAVNDIVSKGRTKKA-..--------.
41 --KK..TNLLS.....VKVFQGESS.STSIILD..GFNWAVNDIVSKGRTKKA-..--------.
42 --AN..TKLVA.....VKVFAGRSA.ALSVINQ..GFTWALNDYISKR------..--------.
43 --KR..VTIFG.....VKVLPARGT.SP-----..-------------------..--------.
44 VAHS..VEIYA.....VKALGNGGY.GS-----..----WSDLIIAIDLAVKGP..DGVIDADG.
45 LAPG..VEILP.....IRMPEKIEG.-------..-------------------..------LD.
46 IAPE..AKILP.....VRVILEDGD.PS-----..-------------------..-------R.
47 VAPM..VQIMP.....VRALGTDGS.GD-----..-------------------..--------.
48 VAPG..ATLAV.....GKVLDDEGF.GS-----..-------------------..--------.
49 VAPD..ATLLA.....YRVLGPGGS.GT-----..-------------------..--------.
50 VAYK..AKVLP.....VRVLGHCGG.SFSDITD..AIVWASGGHVEGVPDN---..--------.
51 TAYG..AKVVP.....VRVLGKCGG.SLSDIAD..AIVWASGGTVSGIPA----..--------.
52 VAYG..AKVIP.....VRVLGKCGG.YDSDITD..GMYWSAGGHIDGVPDN---..--------.
53 VAYG..AKVIP.....VRVLGKCGG.YDSDITD..GMYWSAGGHIDGVPDN---..--------.
54 --PG..AKVIS.....ALVLPNNEG.TF-----..-------------------..--------.
55 AAPG..AKIVS.....AKACVYAGG.CT-----..-------------------..--------.
56 VSPG..TNLLV.....YRVFGKSKS.KE-----..-------------------..--------.
57 VAPD..AKYLT.....AAMFQPGSV.GS-----..-------------------..--------.
58 VAPD..ADLWA.....YKVLLDSGSgYSDDIAA..AIRHAADQATATGT-----..--------.
59 VAPD..ADLWA.....YKVLLDSGSgYSDDIAA..AIRHAADQATATGT-----..--------.
60 VAPE..ADLWA.....YKVLGDDGSgYADDIAE..AIRHAGDQATALN------..--------.
61 VAPD..ADLWA.....YKVLGDDGSgYADDIAA..AIRHAGDQATAL-------..--------.
62 VAPD..AQLLA.....MKVFSNNAK.NSGAYDD..DIISAIEDSVKLG------..--------.
63 IAPR..AQLQG.....FNLLDDNSQ.QL-----..------------------Q..KDWLYALG.
64 VAYN..AQIYV.....GNTNANDSF.LFGP---..-------------------..--------.
65 VAYN..AQLYV.....GNTNANDSF.LFG----..-------------------..--------.
66 VAWK..SQVSG.....IRILSGPIT.SS-DEAE..AMVYGLD------------..--------.
67 VAYN..SKVSG.....IRILSGQIT.AE-----..-------------------..--------.
68 VAYG..SKVAG.....LRMLDQPFM.TD-----..-------------------..--------.
69 VAFG..SKVAG.....LRMLDQPFM.TD-----..-------------------..--------.
70 VAFG..SKVAG.....LRMLDQPFM.TD-----..-------------------..--------.
71 VAFG..SKVAG.....LRMLDQPFM.TD-----..-------------------..--------.
72 GIPR..TGHLNvi6gnVTTGGQSGE.NELDAEW..SGAFAPAANVTIVFSNGYV..------GG.
110 120 130 140 150
| | | | |
1 ....DQSASGNTGLTQAFNQAVSDN.....VAKVINVSLGW.....CEADANADG.....TLQAE
2 ....DQSASGNTGLTQAFNQAVSDN.....VAKVINVSLGW.....CEADANADG.....TLQAE
3 ....NESALPH--------------.....---VHTVSYGD.....DEDSL-SSA.....YIQRV
4 ....NESALPH--------------.....---VHTVSYGD.....DEDSL-SSA.....YIQRV
5 ....NESALPH--------------.....---VHTVSYGD.....DEDSL-SSA.....YIQRV
6 ....NESSLPH--------------.....---VHTVSYGD.....DEDSL-SSI.....YIQRV
7 ....NESSLPH--------------.....---VHTVSYGD.....DEDSL-SSI.....YIQRV
8 esntCQSMLQNQNIVNGINEFVSSN.....SKCQVAL----.....-EQDTQQNY.....HIYSS
9 ....KSASDTNLN---ACIKTLTNL.....HVNHISMSYGG.....SEGDT----.....---SS
10 ....--------SDVLAGIDQAIAD.....GVDVISISLGY.....DGVPLYEDP.....IAIAS
11 gds.SSSGITDAGITASYNRAVTDN.....IAKLINVSLGE.....DETAAQQSG.....TQAAD
12 ....DQSASGNTGLTQAFNQAVSDN.....VAKVINVSLGW.....CEADANADG.....TLQAE
13 ....---------------------.....-----------.....----YLGSG.....YLRRS
14 ....SGLKVIVYRLYGFHHLFATKD.....VPLVNSISYGW.....NEEDQCENGi15aqYVARV
15 ....-------LDAVAQGIREAADS.....GAKVISLSLGA.....PNGGT----.....---AL
16 ....-------LDAVAQGIREAADS.....GAKVISLSLGA.....PNGGT----.....---AL
17 ....-------WTAVANGITYAADQ.....GAKVISLSLGG.....TVGNS----.....---GL
18 ....-------WTAVANGITYAADQ.....GAKVISLSLGG.....TVGNS----.....---GL
19 ....-------LDSIASGIRYAADQ.....GAKVLNLSLGC.....ECNST----.....---TL
20 ....-------LSDIADAIIYAADS.....GAEVINLSLGC.....DCHTT----.....---TL
21 ....-------LSDIADAIIYAADS.....GAEVINLSLGC.....DCHTT----.....---TL
22 ....------SSSLVAAIDTCVTSG.....GANVVTMSLGG.....SGSTT----.....---TE
23 ....-------SSTLVRAIQTCADN.....GAKIVNMSLGG.....SQSSR----.....---TE
24 ....-------SSGIINGVNWCAAQlk8teSKVVISLSLGG.....GRASQ----.....---TE
25 ....DGKRKGFKGS-----------.....---VANMSLGG.....--------G.....KTQAL
26 ....DGKRKGFKGS-----------.....---VANMSLGG.....--------G.....KTQAL
27 ....-------LSNVIAGMDFVASDyr7cpRGVVASMSLGG.....--------G.....YSATV
28 ....-------LSNVIAGMDFVASDyr7cpRGVVASMSLGG.....--------G.....YSATV
29 ....-------LSGVIAGMDFVATDrk7csKGTVASMSLGG.....--------G.....YSATV
30 ....-------YSGIISGMDFVAQDsk7cpNGHIASMSLGG.....--------G.....YSASV
31 ....-------YSGIISGMDYVAQDsk7cpNGAIASMSLGG.....--------G.....YSASV
32 ....-------YSGIISGMDFAVQDsk7cpKGVVANMSLGG.....--------G.....KAQSV
33 ....-------YSGILAGMDFAIQDsr7cpKGVVANMSLGG.....--------G.....YSAAI
34 ....-------NSGVIAGMDFVTKDas7cpKGVVVNMSLGG.....PSSSA----.....----V
35 ....------------SSINWAVGNkgs..AAAVANMSLGG.....--------G.....ASQAV
36 ....---------------------.....-----------.....---------.....-----
37 ....-------YSGVISGIDWVKNNas...GPSVANMSLGG.....--------G.....VSQAV
38 ....--------------------T.....GKSAINMSLGG.....--------G.....YSYAF
39 ....---------------------.....---AINMSLGG.....--------G.....YSYAF
40 ....---------------------.....---AINMSLGG.....--------G.....YSYAF
41 ....---------------------.....---AINMSLGG.....--------G.....YSYAF
42 ....---------------------dtl..PRGVLNFSGGG.....--------P.....KSASQ
43 ....NSVIIKGMDFVHAMPSGVNAP.....TDVVVNMSLGG.....--------G.....YSKAT
44 ....DGVVAGDPD----------DD.....APEVISMSLGG.....SSPPP----.....---EL
45 ....FTSGHNAARDFSKAIRFAADS.....DAKVINISMGQ.....AESGTKGGV.....DTSEL
46 ....AKARKTRGNALAEGIRWAADH.....GADIINLSLGD.....DSASA---H.....PEPGE
47 ....-------ISAVVQAIVWAVDH.....GANIINLSLGS.....NEASE----.....---AL
48 ....-------ESEIIAGMEWAARDv....DADIVSMSLGS.....TEPSDGTDP.....MAEAV
49 ....-------TENVIAGVERAVQD.....GADVMNLSLGNsl...NNPDW----.....---AT
50 ....---------------------re...PAEIINISLGG.....FGPCD----.....--SAM
51 ....------------------NAN.....PAEVINMSLGG.....GGSCS----.....--TTM
52 ....-------------------QN.....PAQVVNMSLGG.....GG------G.....CSQNS
53 ....-------------------QN.....PAQVINMSLGG.....DGDCS----.....--QSS
54 ....AQVIAGMQYVLDPDNNADTDD.....GADVVNMSLGI.....PGTWN----.....---EF
55 ....------SVALTEGMIELVGNQ.....RVDIVNMSIGG.....--LPALNDG.....NNTRS
56 ....--------CWILKAIIDATNN.....GANVINLSLGQyiki.PNGDIWESA.....EALRY
57 ....--------AGVAKAILWMVDN.....GAKVLNNSWGG.....AGFDP----.....---LI
58 ....---------------------.....-KTIISMSLGS.....SANNS----.....---LI
59 ....---------------------.....-KTIISMSLGS.....SANNS----.....---LI
60 ....---------------------.....TKVVINMSLGS.....SGESS----.....---LI
61 ....--------------------N.....TKVVINMSLGS.....SGESS----.....---LI
62 ....---------------------.....-ADVINMSLGS.....VSSDV---G.....PSDPQ
63 ....DSNASRDNRVFNHSYRMSVVD.....PRSANSL----.....DQSQL----.....---DR
64 ....----TPDPQYFKAVYSALVDS.....GVRAINNSWGSq12gdLHAAYAQHY.....NQNTW
65 ....---PTPDPKYFKAVYTALVDS.....GVRAINNSWGSq12agLHAAYAQHY.....NQGTW
66 ....---------------------.....TNDIYSCSWGPt....DNGKVLSEPdviv.KKAMI
67 ....DEAASLIYGL----------D.....VNDIYSCSWGP.....SDDGKTMQApdtlvKKAII
68 ....---------LIEANAMGHMPN.....VIDIYSASWGP.....TDDGKTVDGprnltMRAIV
69 ....---------LIERNAMGHMPN.....VIDIYSASWGP.....TDDGKTVDGprnltMRAIV
70 ....---------LIEANAMGHMPN.....VIDIYSASWGP.....TDDGKTVDGprnltMRAIV
71 ....---------LIEANAMGHMPN.....VIDIYSASWGP.....TDDGKTVDGprnltMRAIV
72 ....PQLVGNLLNYYYEYYYMVNYL.....NPNVISISVTV.....PESFLAAYYpa...MLDMI
160 170 180 190 200
| | | | |
1 DRIFATAAAQGQTFSVSSGDEGVYECNNRGY.....PD.GST.....YSVSWPASSPNVIAVGGT
2 DRIFATAAAQGQTFSVSSGDEGVYECNNRGY.....PD.GST.....YSVSWPASSPNVIAVGGT
3 NTELMKAAARGLTLLFASGDSGAGCWSVSGR.....H-.--Q.....FRPTFPASSPYVTTVGGT
4 NTELMKAAARGLTLLFASGDSGAGCWSVSGR.....H-.--Q.....FRPTFPASSPYVTTVGGT
5 NTEFMKAAARGLTLLFASGDSGAGCWSVSRR.....H-.--Q.....FRPSFPASSPYVTTVGGT
6 NTEFMKAAARGLTLLFASGDTGAGCWSVSGR.....H-.--K.....FRPSFPASSPYVTTVGGT
7 NTEFMKAAARGLTLLFASGDTGAGCWSVSGR.....H-.--K.....FRPSFPASSPYVTTVGGT
8 CTCDK-------LKPYSDSDAGFKIVGYSYD.....QDaGTL.....FQPDYPASSPFITSVGAT
9 DSYFQQAQEAGISLFASAGDSGAE-------.....--.---.....--AEYPAASQYVVAVGGT
10 FAAM----EKGVVVSTSAGNAGPFFGNMH--.....--.---.....------NGIPWVLTVAAG
11 DAIFQQAVAQGQTFSIASGDAGVYQWSTDPTs15vkID.LTH.....YSVSEPASSPYVIQVGGT
12 DRIFATAAAQGQTFSVSSGDEGVYECNNRGY.....PD.GST.....YSVSWPASSPNVIAVGGT
13 DVEFQKLALMGITIIIADGDNGAGDLGAPPMlt...PD.CSTr....LNPDWP--SQRLTSRLGL
14 NTEFQKIGLRGITLFAASGDSGAN-GRTDPD.....CS.ESN.....LNPAYPAASPYITSVGAT
15 QQAVQYAWNKGSVIVAAAGNAGNT-------.....--.---.....-KANYPAYYSEVIAVAST
16 QQAVQYAWNKGSVIVAAAGNAGNT-------.....--.---.....-KANYPAYYSEVIAVAST
17 QQAVNYAWNKGSVVVAAAGNAGNT-------.....--.---.....-APNYPAYYSNAIAVAST
18 QQAVNYAWNKGSVVVAAAGNAGNT-------.....--.---.....-APNYPAYYSNAIAVAST
19 KSAVDYAWNKGAVVVAAAGNDNVS-------.....--.---.....-RTFQPASYPNAIAVGAI
20 ENAVNYAWNKGSVVVAAAGNNGSS-------.....--.---.....-TTFEPASYENVIAVGAV
21 ENAVNYAWNKGSVVVAAAGNNGSS-------.....--.---.....-TTFEPASYENVIAVGAV
22 RNALNTHYNGGVLLIAAAGNAGDS-------.....--.---.....-TYTYPPSYDIVMSVAAV
23 QNAMDALYERGVLMIAAAGNSGNT-------.....--.---.....-AHSYPASYDSVMSVAAV
24 QRAYTSVYNKGVLTVAATGNDGAA-------.....--.---.....--VSYPAAYTNVVGVGAI
25 DAAVNAAVKAGIHFAVAAGNDNADACNYS--.....--.---.....-----PAAAELPVTVGAS
26 DAAVNAAVKAGIHFAVAAGNDNADACNYS--.....--.---.....-----PAAAELPVTVGAS
27 NQAAARLQSSGVFVAVAAGNDNRDAANTS--.....--.---.....-----PASEPSVCTVGAT
28 NQAAARLQSSGVFVAVAAGNDNRDAANTS--.....--.---.....-----PASEPSVCTVGAT
29 NQAAARLQASGVFVAVAAGNDNRDAAQTS--.....--.---.....-----PASEPSVCTVGAT
30 NQGAAALVRSGVFLAVAAGNDNRDAQNTS--.....--.---.....-----PASEPTACTVGAT
31 NQGAAALVNSGVFLAVAAGNDNRDAQNTS--.....--.---.....-----PASEPSACTVGAS
32 NDGAAAMIRAGVFLAVAAGNDNANAANYS--.....--.---.....-----PASEPTVCTVGAT
33 NQAAAKMIQSNVFLAVAAGNDAKDASQTS--.....--.---.....-----PASEPSVCTVGAT
34 NRAAAEITSAGLFLAVAAGNEATDASSSS--.....--.---.....-----PASEESACTVGAT
35 DDAVNNAASKNLVMAVAAGNENQNACNVS--.....--.---.....-----PARAVNAITVGAT
36 -------------------------------.....--.---.....------GNGYTAITRGLT
37 DDAVNNAVASGVSFVVAAGNDNSNACNYS--.....--.---.....-----PARAANAITVGST
38 NQAVEDAYDEGVLSVVAAGNDNIDASDSS--.....--.---.....-----PASAPNALTVAAS
39 NNAVENAFDEGVLSVVAAGNENSDASNTS--.....--.---.....-----PASAPNALTVAAI
40 NNAVENAFDEGVLSVVAAGNENSDASNTS--.....--.---.....-----PASAPNALTVAAI
41 NNAVENAFDEGVLSVVAAGNENSDASNTS--.....--.---.....-----PASAPNALTVAAI
42 DALWSRATQEGLLVAIAAGNDAVDACNDS--.....--.---.....-PGNIGGSTSGIITVGSI
43 NQAAARLVRAKYFVAVASGNNNRDARNYS--.....--.---.....-----PASEPSVCTVGGT
44 HDVIKAAYNLGITIVAAAGNDGAD-------.....--.---.....-SPSYPAAYPEVIAVGAI
45 DAAVKYAVDKGKLIFAAAGNEGDG-------.....--.--A.....NRPRFPASTPGVVAVGSI
46 DEAIQYALKKGVVVVASAGNGGEL-------.....--.--G.....DHISYPAAYPGVIAATAV
47 QSAVRYADEKGVAVVAAAGNAGNN-------.....--.ELT.....YPAAYARTSAGLLSVGSV
48 NTLSR---ETGALFVIAAGNTGAP-------.....--.---.....SSIGSPGAADAALTVGAV
49 STALDWAMSEGVVAVTSNGNSGPN-------.....--.--G.....WTVGSPGTSREAISVGAT
50 QAAINGAVSRGTTVVVAAGNGGSD-------.....--.---.....VSSAVPANCANVVSVAAT
51 QNAINGAVSRGTTVVVAAGNDASN-------.....--.---.....VSGSLPANCANVIAVAAT
52 QRMIDKTTNLGALIVIAAGNENQD-------.....--.---.....ASRTWPSSCNNVLSVGAT
53 QRIIDKTTNLGALIVIAAGNENQD-------.....--.---.....ASRTWPSSCNNVLSVGAT
54 IVPVNNMLKAGVVPVFAIGNFGPA-------.....--.--A.....GSTGSPGNLPQAIGVGAV
55 ALYNRIIDEYGVQIFISAANSGAG-------.....--.--T.....NTIADPSVATDAVSVAAG
56 KFAIDYATRHNVIVVAATGNDGLSDDNGEVKt11qdMS.QND.....TVEDYPSVLPNAIAVGSS
57 KAAMDYALERNVTVVVSAGNESRE-------.....--.---.....-YYQRPALFAGVIPSAAL
58 SSAVNYAYSKGVLIVAAAGNSGYA-------.....--.--Q.....GTIGYPGALPNAIAVAAL
59 SSAVNYAYSKGVLIVAAAGNSGYS-------.....--.--Q.....GTIGYPGALPNAIAVAAL
60 TNAVDYAYDKGVLIIAAAGNSGPK-------.....--.--P.....GSIGYPGALVNAVAVAAL
61 TNAVNYSYNKGVLIIAAAGNSGPY-------.....--.--Q.....GSIGYPGALVNAVAVAAL
62 QQAVAKASEAGVINVISAGNSGVAGSTADGN.....PV.NNTgtselSTVGTPGVTPDALTVASA
63 LFEQQTLKAQGAAYIKAAGN-GFNKIAAGGYv10pkLP.FEN.....SNLDPSNSNFWNLVVSAL
64 LDAAADVAKAGVINVFSAGNSGYANASVR--.....--.-SA.....LPYFQPGLEGHWLAVSGL
65 LDAAADVAKAGVINVFSAGNSGYANASVR--.....--.-SA.....LPYFQPELEGHWLAVSGL
66 KGIQEGRDKKGAIYVFASGNGGRF-------.....--.GDS.....CNFDGYTNSIYSITVGAI
67 KGVTEGRDAKGALYVFASGNGGMF-------.....--.GDS.....CNFDGYTNSIFSITVGAI
68 NGVNNGRNGLGNVYVWASGDGGPN-------.....--.-DD.....CNCDGYAASMWTISINSA
69 NGVNNGRNGLGNVYVWASGDGGPN-------.....--.-DD.....CNCDGYAASMWTVSINSA
70 NGVNNGRNGLGNVYVWASGDGGPN-------.....--.-DD.....CNCDGYAASMWTVSINSA
71 NGVNNGRNGLGNVYVWASGDGGPN-------.....--.-DD.....CNCDGYAASMWTVSINSA
72 HNIMLQAAAQGISVLAASGDWGYESDHPPPN.....FHiGTY.....NTIWYPESDPYVTSVGGI
210 220 230 240 250
| | | | |
1 TLYTTSA.GAY.....SNE.....TVWNEGL.....DSNGKLWATGGGYSVYESKPSWQSVVSGT
2 TLYTTSA.GAY.....SNE.....TVWNEGL.....DSNGKLWATGGGYSVYESKPSWQSVVSGT
3 SFQEPF-.---.....---.....-----LI.....TNEIVDYISGGGFSNVFPRPSYQEEAVTK
4 SFQEPF-.---.....---.....-----LI.....TNEIVDYISGGGFSNVFPRPSYQEEAVTK
5 SFQNPFR.---.....---.....------V.....TTEIVDYISGGGFSNVFPQPSYQEEAVVQ
6 SFKNPF-.---.....---.....-----LI.....TDEVVDYISGGGFSNVFPRPPYQEEAVAQ
7 SFKNPF-.---.....---.....-----LI.....TDEVVDYISGGGFSNVFPRPPYQEEAVAQ
8 QITDVTK.PEI.....VCS.....-------.....VATGAIITGGGGVAITQAQPSYQADAVAT
9 TLHTNSD.GSF.....NSE.....-------.....---TAWSGSGGGCSKYTKVIPEQNADPGY
10 NIDRSFA.GTL.....TLGn64snVAGAILI.....SNHTKLFELGGGVSCPCLVISPKDAAALI
11 TLSTS-G.TTW.....SGE.....TVWNEGLsa8qgDNNQRLWATGGGVSLYEAAPSWQSSVSSS
12 TLYTTSA.GAY.....SNE.....TVWNEGL.....DSNGKLWATGGGYSVYESKPSWQSVVSGT
13 YIHHTLA.EPI.....CYT.....DIDCRLDnp9vsLDNGLFWTTGGGFADYPPRPQYQEAIISQ
14 QISQSSG.VAK.....LPNp27ilHQVEDFL.....WLPQHCLSEGSHCSILQVRCNLASKLLLQ
15 DQSDRKS.SFS.....TYG.....-------.....-----------------------------
16 DQSDRKS.SFS.....TYG.....-------.....-----------------------------
17 DQNDNKS.SFS.....TYG.....-------.....-----------------------------
18 DQNDNKS.SFS.....TYG.....-------.....-----------------------------
19 DSNDRKA.SFS.....NYG.....-------.....-----------------------------
20 DQYDRLA.SFS.....NYG.....-------.....-----------------------------
21 DQYDRLA.SFS.....NYG.....-------.....-----------------------------
22 DSNLDHA.AFS.....QYTd108aGAKGIIV.....YSNTALPRLQNPFVVDAD--SEILIPSMS
23 DSNYDHA.SFS.....QATn109aGALAAMV.....YSNQQ--RPGLQNPFVLDQFNTYPLLSVS
24 DSAEARA.SFS.....NFG.....-------.....---SQVDLVGPGVSVLSSIPLGQGTRASA
25 AFDDSRA.YFS.....NYG.....-------.....-----------------------------
26 AFDDSRA.YFS.....NYG.....-------.....-----------------------------
27 DSSDRRS.SFS.....NYG.....-------.....-----------------------------
28 DSSDRRS.SFS.....NYG.....-------.....-----------------------------
29 DSSDRRS.TFS.....NFG.....-------.....-----------------------------
30 ASDDSRS.TFS.....NYG.....-------.....-----------------------------
31 AENDSRS.SFS.....NYG.....-------.....-----------------------------
32 TSSDARS.SFS.....NYG.....-------.....-----------------------------
33 DSSDRLS.SFS.....NYG.....-------.....-----------------------------
34 DKTDTLA.EYS.....NFG.....-------.....-----------------------------
35 TKTDSRDtGYS.....NYG.....-------.....-----------------------------
36 TNTDARW.SFS.....NYG.....-------.....-----------------------------
37 TSSDARS.SFS.....NYG.....-------.....-----------------------------
38 TKSNTRA.SFS.....NYG.....-------.....-----------------------------
39 NKSNARA.SFS.....NYG.....-------.....-----------------------------
40 NKSNARA.SFS.....NYG.....-------.....-----------------------------
41 NKSNARA.SFS.....NYG.....-------.....-----------------------------
42 DSSDKIS.VWSggqgsNYG.....-------.....-----------------------------
43 DKFDSV-.YMS.....NWG.....-------.....---PAVDINGPGVDVLSTLPNRRTVCFF-
44 DENGNVP.SWS.....NRN.....-------.....-----------------------------
45 NEKVKRS.SFS.....EWG.....-------.....-----------------------------
46 DRYGTRA.AFS.....TRR.....-------.....-----------------------------
47 SDSDVKS.GFS.....NYA.....-------.....-----------------------------
48 DSADQAA.WFT.....SAG.....-------.....--------------------------PRY
49 QLPLNE-.YAV.....TFGs117kLTVSKAL.....GEQVADFSSRGPVMDTWM-----------
50 RLTGGLA.YYS.....NFG.....-------.....-SLIDLAAPGGGARDLETDTLYDGPIG--
51 TSAGAKA.SYS.....NFG.....-------.....-----------------------------
52 TPKGKRA.PFS.....NYG.....-------.....-----------------------------
53 TPKGKRA.PFS.....NYG.....-------.....-----------------------------
54 DSNGQVA.SFS.....SRG.....-------.....------------------PVAWQGEISGV
55 ASKETW-.-LA.....NYG.....AKAKEEYwaqn.YSSRGPREDGGFKPNIMAPGSAISAVPMF
56 DNNNQRS.SFS.....NYY.....-----NQ.....YQDNFILAPGGGTPLLDQ--YGQEEWYNQ
57 AVNNTKA.SFS.....SFG.....-------.....---RHISVAAPGTDILMASPLFINDDGTR
58 ENVQQNG.TYR.....VAD.....-------.....YSSRGYISTAGDYVIQE------------
59 ENVQQNG.TYR.....VAD.....-------.....YSSRGYISTAGDYVIQE------------
60 ENTIQNG.TYR.....VAD.....-------.....FSSRGHKRTAGDYVIQK------------
61 ENKVENG.TYR.....VAD.....-------.....FSSRGYSWTDGDYAIQK------------
62 ENSKVTT.DTV.....KDEl116wLKQQKKV.....RASRLKFGTALIDNSRAGKMSDFTSWGPT
63 NADGVRS.SYS.....SVG.....-------.....-SNIFLSATGGEYGTDTP-----------
64 DKANNQK.---.....---.....-------.....--------------------------YNQ
65 DKTNNQK.---.....---.....-------.....--------------------------YNK
66 DYKGLHP.QYS.....EAC.....-------.....---------------------------SA
67 DWKGLHP.PYS.....ESC.....-------.....---------------------------SA
68 RNDGQTA.GYD.....ESC.....-------.....-SSTLASTFSNGKSN--------------
69 TNDGQTA.GYD.....ESC.....-------.....---------------------------SS
70 TNDGQTA.GYD.....ESC.....-------.....---------------------------SS
71 TNDGQTA.GYD.....ESC.....-------.....---------------------------SS
72 FLNASSN.GSI.....VEI.....-------.....--SGWDYSTGGNSVVYPAQIYEITSLIPF
260 270 280 29
| | |
1 .....PG.....RRLLPDISFDAAQG.....TGALIY.....NYGQ.....LQQIG....GTSLA
2 .....PG.....RRLLPDISFDAAQG.....TGALIY.....NYGQ.....LQQIG....GTSLA
3 .....FLs15asGRAYPDVAALSDGY.....WVVSNR.....V--P.....IPWVS....GTSAS
4 .....FLs15asGRAYPDVAALSDGY.....WVVSNR.....V--P.....IPWVS....GTSAS
5 .....FLs15asGRAYPDVAALSDGY.....WVVSNS.....V--P.....IPWVS....GTSAS
6 .....FLk15asGRAYPDVAALSDGY.....WVVSNM.....V--P.....IPWVS....GTSAS
7 .....FLk15asGRAYPDVAALSDGY.....WVVSNM.....V--P.....IPWVS....GTSAS
8 .....YIks...GTLPPSYSYMPPID.....SIQILLl17ntCPCA.....LESVD....GTSCS
9 aslgcKG.....KKALPDLAALADPN.....SGITII.....FHGQe....LEGIG....GTSLA
10 .....KYa39ypGILKPDVM--APGS.....LVLASW.....IPNEa14shYNMVS....GTSMA
11 .....T-.....KRVGPDLAFDAASS.....SGALIV.....VNGS.....TEQVG....GTSLA
12 .....PG.....RRLLPDISFDAAQG.....TGALIY.....NYGQ.....LQQIG....GTSLA
13 .....YLq15sgGRAYPDIS---TVG.....HNLMTV.....ISGS.....MTPVD....GTSPS
14 .....CC.....CKRISDVS---ALG.....SAILIE.....TGGN.....IQTVG....GTSAS
15 .....--.....----SWVDVAAPGS.....NIYSTY.....KGST.....YQSLS....GTSMA
16 .....--.....----SWVDVAAPGS.....NIYSTY.....KGST.....YQSLS....GTSMA
17 .....--.....----SWVDVAAPGS.....SIYSTY.....PTST.....YASLS....GTSMA
18 .....--.....----SVVDVAAPGS.....WIYSTY.....PTST.....YASLS....GTSMA
19 .....--.....----TWVDVTAPGV.....NIASTV.....PNNG.....YSYMS....GTSMA
20 .....--.....----TWVDVVAPGV.....DIVSTI.....TGNR.....YAYMS....GTSMA
21 .....--.....----TWVDVVAPGV.....DIVSTI.....TGNR.....YAYMS....GTSMA
22 .....VD.....RTTGLALKAKLGQS.....TTVSNQ.....GNRD.....YEYYN....GTSMA
23 .....VN.....RNVGQELAALVGQD.....ITVSTR.....TGED.....YQYYN....GTSMA
24 s....GG.....GVTFTDVS--AADK.....SGKATFs103vTGAD.....YDFFD....GTSMA
25 .....--.....----KCTDIFAPGL.....NILSTW.....IGSPta...VNTIS....GTSMA
26 .....--.....----KCTDIFAPGL.....NILSTW.....IGSPta...VNTIS....GTSMA
27 .....--.....----RALDIFAPGT.....DITSTW.....IGGR.....TNTIS....GTSMA
28 .....--.....----RALDIFAPGT.....DITSTW.....IGGR.....TNTIS....GTSMA
29 .....--.....----KAVDIFAPGT.....GILSTW.....NNGG.....TNTIS....GTSMA
30 .....--.....----RIVDIFAPGT.....GILSTW.....INGR.....TNTIS....GTSMA
31 .....--.....----RVVDIFAPGS.....NVLSTW.....IVGR.....TNSIS....GTSMA
32 .....--.....----NLVDIFAPGS.....NILSTW.....IGGT.....TNTIS....GTSMA
33 .....--.....----AAVDILAPGS.....DILSTW.....IGGI.....TKSIS....GTSMA
34 .....--.....----SVVDLLAPGT.....DIKSTW.....NDGR.....TKIIS....GTSMA
35 .....--.....----SCLDIFAPGT.....NITSTW.....IGSTsa...TNTIS....GTSMA
36 .....--.....----SCLDIFAPGS.....SITSAW.....YTSSta...TNTIS....GTSMA
37 .....--.....----NCLDIYAPGS.....SITSAW.....YNSDts...TNTIS....GTSMA
38 .....--.....----SVVDIFAPGQ.....DILSAW.....IGSTta...TNTIS....GTSMA
39 .....--.....----SVVDIFAPGQ.....DILSAW.....IGSTta...TNTIS....GTSMA
40 .....--.....----SVVDIFAPGQ.....DILSAW.....IGSTta...TNTIS....GTSMA
41 .....--.....----SVVDIFAPGQ.....DILSAW.....IGSTta...TNTIS....GTSMA
42 .....--.....----TCVDVFAPGS.....DIISAS.....YQSDsg...TLVYS....GTSMA
43 .....--.....----FLIKIPAWRA.....EELTCM.....MQGR.....LT---....GTSMA
44 .....--.....----PEVA--APGV.....NILSTY.....PDDT.....YEELS....GTSMA
45 .....--.....----PEIDVTAPGE.....DLVHAC.....IGGTg....VCRTS....GTSDA
46 .....--.....--WYATVS--APGV.....DVIIAD.....PDHR.....YYEGW....GTSAA
47 .....--.....----ASLEVLAPGE.....RIATYA.....PNNK.....LALWT....GTSMS
48 .....GD.....NALKPDLS--APGV.....GILAARsrlaeGSGD.....YTSMD....GTSMA
49 .....--.....--IKPDIS--APGV.....NIVSTI.....PTHDpd6ygYGSKQ....GTSMA
50 .....--.....----SWIW--QTGY.....TGATTP.....TSGQ.....FTYIGpgfaGTSMA
51 .....--.....----TGIDVSAPGS.....SILSTL.....NSGTtt7asYASYN....GTSMA
52 .....--.....----ARVHLAAPGT.....NILSTI.....DVGQag7ssYGMKA....GTSMA
53 .....--.....----ARVHLAAPGT.....NILSTI.....DVGQag7ssYGMKA....GTSMA
54 .....F-.....--TKPDIA--APGV.....NITSTV.....RNGG.....YQAMS....GSSQA
55 .....MD.....PEDIPQVSYKLPV-.....------.....---G.....LSMFN....GTSMA
56 .....KL.....----------FMKE.....QVLSTS.....NNGN.....YDYAD....GTSIS
57 .....KL.....GATPPDGS------.....------.....---G.....YVLMS....GTSFS
58 .....--.....----GDIEISAPGS.....SVYSTW.....YNGG.....YNTIS....GTSMA
59 .....--.....----GDIEISAPGS.....SVYSTW.....YNGG.....YNTIS....GTSMA
60 .....--.....----GDVEISAPGA.....AVYSTW.....FDGG.....YATIS....GTSMA
61 .....--.....----GDVEISAPGA.....AIYSTW.....FDGG.....YATIS....GTSMA
62 .....PE.....LDFKPEIT--APGG.....KIYSLA.....NDNK.....YQQMS....GTSMA
63 .....--.....----AMVTTDLPGC.....DMGYNR.....TDDPs17dyNGVMN....GTSSA
64 .....CG.....IAKYWCIS--TPGA.....LINSTI.....PEGG.....YGVKS....GTSMS
65 .....CG.....IAKYWCIS--TPGA.....LINSTV.....PGGG.....YGVKS....GTSMS
66 .....VM.....VVTYSSGS----GE.....HIHTTD.....IKKKc....SATHG....GTSAA
67 .....VM.....VVTYSSGS----GN.....YIKTTD.....LDEKc....SNTHG....GTSAA
68 .....--.....----------SRDA.....GVATTD.....LYNNc....TASHS....GTSAA
69 .....TL.....ASTFSNGKSSSRDA.....GVATTD.....LYNNc....TASHS....GTSAA
70 .....TL.....ASTFSNGKSSSRDA.....GVATTD.....LYNNc....TASHS....GTSAA
71 .....TL.....ASTFSNGKSSSRDA.....GVATTD.....LYNNc....TASHS....GTSAA
72 tp...VI.....VRTYPDIAFVSAGGyn7fgFGLPLV.....FQGQ.....LFVWY....GTSGA
0 300 310 320 330
| | | | |
1 SPIFVGLWARLQSANS.....NSLGFPAASFYSAIS...STPS.....LVHDVKSGNNG.....Y
2 SPIFVGLWARLQSANS.....NSLGFPAASFYSAIS...STPS.....LVHDVKSGNNG.....Y
3 TPVFGGILSLINEHRIlsgr.PPLGFLNPRLYQQHG...AGL-.....--FDVTRGCHEsc6eeV
4 TPVFGGILSLINEHRIlsgr.PPLGFLNPRLYQQHG...AGL-.....--FDVTRGCHEsc6eeV
5 TPVFGGILSLINEHRLlsgl.PPLGFLNPRLYQQRG...AGL-.....--FDVTRGCHEsc6eeV
6 TPVFGGILSLINEHRIlngr.PPLGFLNPRLYQQHG...TGL-.....--FDVTHGCHEsc6eeV
7 TPVFGGILSLINEHRIlngr.PPLGFLNPRLYQQHG...TGL-.....--FDVTHGCHEsc6eeV
8 SPTLAGMISLINDKLIgagk.PTLGFLNPLLYQAAK...EQPN.....VFNDITTGANNcnrayC
9 APLTAGRAAIRGDQVT.....----------PAYVY...TGGI.....QFRDITQGSNG.....H
10 CPHASGVAALLKAAHP.....---EWSPAAIRSAMM...TTA-.....--NPLDNTLNP.....I
11 SPLFVGAFARIESAAN.....NAIGFPASKFYQAFP...TQTS.....LLHDVTSGNNG.....Y
12 SPIFVGLWARLQSANS.....NSLGFPAASFYSAIS...STPS.....LVHDVKSGNNG.....Y
13 ATIFAGIVSLLTDARLragk.PALGFLNPLLYQIAA...EA--.....LMHSVCSG---.....-
14 SPIFAGVVGLLNDYVNsktg.KPLGFVSPLLYKMAA...ERPA.....AFFDVIKGDNI.....C
15 TPHVAGVAVLLANQ--.....---GYSNTQIRQIIE...STT-.....---DKISGTGT.....Y
16 TPHVAGVAALLANQ--.....---GYSNTQIRQIIE...STT-.....---DKISGTGT.....Y
17 TPHVAGVAGLLASQ--.....---GRSASNIRAAIE...NTA-.....---DKISGTGT.....Y
18 TPHVAGVAGLLASQ--.....---GRSASNIRAAIE...NTA-.....---DKISGTGT.....Y
19 SPHVAGLAALLASQ--.....---GKNNVQIRQAIE...QTA-.....---DKISGTGT.....N
20 SPHVAGLAALLASQ--.....---GRNNIEIRQAIE...QTA-.....---DKISGTGT.....Y
21 SPHVAGLAALLASQ--.....---GRNNIEIRQAIE...QTA-.....---DKISGTGT.....Y
22 TPHVSGVATLVWSYHP.....---ECSASQVRAALN...ATAD.....DL---------.....-
23 TPHVSGVAGLVWSYHP.....---QCSAKQIRQALT...QTA-.....-----------.....-
24 TPHVSAAAAVVWAAKP.....---TLTNTQLLNLLT...STAK.....DL---------.....-
25 SPHICGLLAYYLSLQPag6efSVASITPKQLKDTLIei.STQG.....VLTDIPNDTPN.....-
26 SPHICGLLAYYLSLQPag6efSVASITPKQLKDTLIei.STQG.....VLTDIPNDTPN.....-
27 TPHIAGLGAYLLALE-.....---GGSASTICARIQtl.STKN.....AISGVPSGTVN.....Y
28 TPHIAGLGAYLLALE-.....---GGSASTICARIQtl.STKN.....AISGVPSGTVN.....Y
29 TPHIAGLGAYLLALG-.....---KGTAGNLCQTIQtl.STKN.....VLTGVPSGTVN.....Y
30 TPHIAGLAAYFSALSG.....---KTSPAALCQKIQdt.STKN.....VIRNVPAGTVN.....F
31 TPHIAGLAAYLSALQG.....---KTTPAALCKKIQ...DTATkn...VLTGVPSGTVN.....Y
32 TPHIVGLGAYLAGLE-.....---GFPGAQALCKRIqtlSTKN.....VLTGIPSGTVN.....Y
33 TPHIVGLGAYLSSLEGf....PGAQALCERIRSLAI...RNT-.....-----------.....-
34 SPHVAGLGAYFLGLGQ.....KVQGL----------...----.....-----------.....-
35 TPHVTGAVALLIAEG-.....---NTTTSAVTSALL...NN--.....-----------.....-
36 SPHVAGAAALYLALNP.....---SATPAQVTTAIIna.STPN.....KVTGAQTGSPN.....-
37 APHVAGAVALYLDENP.....---SLSPSQIDSLLS...QRSSkg...KVSNPQSGSP-.....-
38 TPHVVGLSLYLIALEG.....---LSSASAVVSRIK...E---.....-----------.....-
39 TPHIVGLSVYLMGLENl....----SGPA-------...----.....-----------.....-
40 TPHIVGLSVYLMGLENl....----SGPA-------...----.....-----------.....-
41 TPHIVGLSVYLMGLEN.....---LSGP--------...----.....-----------.....-
42 CPHVAGLASYYLSIND.....--EVLTPAQVEALIT...ESN-.....-----------.....-
43 TPHIAGLGAYLAAKNG.....---RRAGPGLCRTIK...----.....-----------.....-
44 TPHVSGTVALIQAARL.....-AAGLPLLPPGSESD...TTPD.....TVRGVLHTTAT.....D
45 TAIASASAALVWSKHP.....---TWTNNQVLRVLI...NTM-.....------KGNEE.....E
46 SAFVSGAAALVKAAHP.....---DLTPAQVKSVLE...DTA-.....--RNAPAG---.....-
47 APVVAGLLALMQGERQ.....-AAGGENAVTAHAHD...ISGI.....ALNQPFTG---.....-
48 TPHIAGVAALLAEEHP.....---DWSGARLKDALM...STSK.....-ELDVS-----.....-
49 SPHIAGAVAVIKQAKP.....---KWSVEQIKAAIM...NTAV.....TLKD-------.....-
50 SPHVAGTAALVQSALIad...GKAPLTPAALERLLK...RSAR.....AF---------.....-
51 SPHVAGVVALVQSVAP.....--TALTPAAVETLLK...NTAR.....ALPGACSG---.....-
52 APHVSGVAALVISAANs....IGKTLTPSELSDILV...RTTS.....RFNG-------.....-
53 APHVSGVAALVISAANs....IGKTLTPSELSDILV...RTTS.....RFNG-------.....-
54 SPITAGAVAVLLSAKP.....---GASVDAIKNALF...TSA-.....-----------.....-
55 RP--------------.....---------------...----.....-----------.....-
56 TGKVSGELAEIISNYH.....--LQGDSSKARSILL...NQVN.....-----------.....-
57 GPYTAATAALILGAHP.....---ELDPYQVRRLME...ETA-.....---DGSVGENP.....N
58 TPHVSGLAAKIWAENP.....---SLSNTQLRSNLQ...ERA-.....KSVDIKGG---.....-
59 TPHVSGLAAKIWAENP.....---SLSNTQLRSNLQ...ERA-.....KSVDIKGG---.....-
60 SPHAAGLAAKIWAQSP.....---AASNVDVRGELQ...TRA-.....SVNDILSGN--.....-
61 SPHAAGLAAKIWAQYP.....---SASNVDVRGELQ...YRA-.....YENDILSG---.....-
62 SPFVAGSEALILQGIKk....QGLNLSGEELVQFAK...NSA-.....-----MNTSHP.....V
63 TPSTSGAMALLMSAYP.....---DLSVRDLRDLLA...RSATrv8qpVMVSYTSSTGKvr7glE
64 APHATGALALVMERYP.....---YLNNEQALQVLL...TTAT.....QLNGAVTDAPT.....T
65 APHATGALALVMERYP.....---YMTNEQALQVLL...TTAT.....QLDG-------.....-
66 APLASGIYSLILSANP.....-NLTWRDVQYISVLS...ATPI.....NEEDGNYQTT-.....-
67 APLAAGIYTLVLEANP.....-NLTWRDVQYLSILS...SEEI.....NPHDGKWQDTA.....M
68 APEAAGVFALALEANR.....-NLTWRDMQHLTVLT...SKR-.....--NSLYDSNGI.....H
69 APEAAGVFALALEANK.....-NLTWRDMQHLTVLT...SKR-.....--NSLYDSNGI.....H
70 APEAAGVFALALEANK.....-NLTWRDMQHLTVLT...SKR-.....--NSLYDSNGI.....H
71 APEAAGVFALALEANK.....-NLTWRDMQHLTVLT...SKR-.....--NSLYDSNGI.....H
72 APMTAAMVALAGTR--.....--LGALNFALYHISY...QGIIe11kvAWIPITSGNNP.....L
340 350 360 370
| | | |
1 GGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNGFGH
2 GGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNGFGH
3 EGQGFCSGPGWDPVTGWGTPNFPAL-----------
4 EGQGFCSGPGWDPVTGWGTPNFPAL-----------
5 QGQGFCSGPGWDPVTGWGTPNFPAL-----------
6 EGQGFCSGPGWDPVTGWGTPNFPAL-----------
7 EGQGFCSGPGWDPVTGWGTPNFPALL----------
8 CQYGYTATTGYDAASGLGSINFKNFEQYVL------
9 -----SAKAGLDLVTGEG------------------
10 HENGKKFHLASPLAMGAGHIDPN-------------
11 QSHGYTAATGFDEATGFGSFDIGKLNTYAQAN----
12 GGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNG---
13 -----------------GRKQMQKLSIH--------
14 TEDGCSS-----------------------------
15 WKN--------------GRVNA--------------
16 WKN--------------GRVNA--------------
17 WAKG--------------------------------
18 WAKG--------------------------------
19 FKYG--------------------------------
20 FKYG--------------------------------
21 FKYG--------------------------------
22 ------SVAGRDNQTGYGMVNATTAKAYL-------
23 -------------------LDLDVLARYIVLD----
24 ------GAAGKDNDFGSGLVN---------------
25 ------------------------------------
26 ------------------------------------
27 ------------------------------------
28 ------------------------------------
29 ------------------------------------
30 L-----------------------------------
31 L-----------------------------------
32 ------------------------------------
33 ------------------------------------
34 ------------------------------------
35 ------ATTGKLSSIGTGSPN---------------
36 ------------------------------------
37 ------------------------------------
38 ------------------------------------
39 ------------------------------------
40 ------------------------------------
41 ------------------------------------
42 ------------------------------------
43 ------------------------------------
44 -----AGDPGYDSLYGYGIIDAYD------------
45 WTHNESFGYG--------------------------
46 ---------GRDDSRGFGFVDPA-------------
47 -------------GLGYGRIDAA-------------
48 -----------AYQLGAGRVS---------------
49 ------------------------------------
50 -----PVQIPLATPAGSGIVDAGA------------
51 -------------GCGAGIVNADAAV----------
52 ---------RLDRGLGSGIVDANA------------
53 ---------RLDRGLGSGIVDANA------------
54 -----SNASAKNNNVGFGQISI--------------
55 ------------------------------------
56 ------------------------------------
57 ---------GFDRGTGYGRIQLGELAQRLQSGPMP-
58 ----YGAAIGDDYASGFGF-----------------
59 ----YGAAIGDDYASGFGF-----------------
60 -----SAGSGDDIASGFGF-----------------
61 ----YYAGYGDDFASGFGF-----------------
62 YDTEHTKEIISPRRQGSGEIN---------------
63 GWERNAAGMWFSPTYGFGLIDVNK------------
64 -------------QVGWGVPDLG-------------
65 -----SITQAPNTVVGWGVPDLG-------------
66 -----ALNRKYSHKYGYGKTDAYKMVHF--------
67 -------GKRYSHTYGFGKLDAYNIVHMAK------
68 HWKLNGAHLLFNHLFGYGVLDAAS------------
69 HWKLNGAHLLFNHLFGYGVLDAASM-----------
70 HWKLNGAHLLFNHLFGYGVLDAASM-----------
71 HWKLNGAHLLFNHLFGYGVLDAASM-----------
72 -----PAHYGWNYVTGPGTYNAYAM-----------