a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1999.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0103 Pepstatin insensitive carboxyl proteinase, Pseudomonas sp.
- gi|1172505|sp|P42790|PICP_PSESR_216:587 PSEUDOMONAPEPSIN PRECURSOR (PEPSTATIN-INSENSITIVE CARBOXYL PROTEINASE) (Pseudomonas sp. 101)
- gi|1073066|pir||A55368 xanthomonapepsin (EC 3.4.23.33) precursor - Pseudomonas sp (Pseudomonas sp.)
- gi|688417|dbj|BAA07188.1| (D37970) prepro-PCP [Pseudomonas sp.] (Pseudomonas sp.)
- gi|1332716|gb|AAB36054.1|_1:369 pepstatin-insensitive carboxyl proteinase {EC 3.4.23.33} [Pseudomonas, No. 101, Peptide, 370 aa] (Pseudomonas)
- gi|1583736|prf||2121360A carboxypeptidase [Pseudomonas sp.] (Pseudomonas sp.)
- gi|3212271|pdb|1A2Q|_48:272 Subtilisin Bpn' Mutant 7186 (Bacillus amyloliquefaciens)
- gi|773560|emb|CAA24990.1|_149:373 (X00165) precursor subtilisin [Bacillus amyloliquefaciens] (Bacillus amyloliquefaciens)
- gi|494622|pdb|1SUD|_48:272 Subtilisin Bpn' Crb-S3 (E.C.3.4.21.62) Mutant With Met 50 Replaced By Phe, Tyr 217 Replaced By Lys, Asn 218 Replaced By Ser, And Ser 221 Replaced By Cys (M50p,Y217k, N218s,S221c) (Bacillus amyloliquefaciens)
- gi|135015|sp|P00782|SUBT_BACAM_155:379 SUBTILISIN BPN' PRECURSOR (SUBTILISIN NOVO) (ALKALINE PROTEASE) (Bacillus amyloliquefaciens)
- gi|67620|pir||SUBSN subtilisin (EC 3.4.21.62) BPN' precursor - Bacillus amyloliquefaciens (Bacillus amyloliquefaciens)
- gi|142526|gb|AAB05345.1| (K02496) preproalkaline protease (gtg start codon) [Bacillus amyloliquefaciens] (Bacillus amyloliquefaciens)
- gi|494620|pdb|1SUB|_48:272 Subtilisin Bpn' Crb-S3 (E.C.3.4.21.62) Mutant With Asn 218 Replaced By Ser, And Ser 221 Replaced By Cys (N218s,S221c) (Bacillus amyloliquefaciens)
- gi|5542495|pdb|1UBN|A_48:272 Chain A, Selenosubtilisin Bpn (Bacillus amyloliquefaciens)
- gi|1311102|pdb|1SUP|_48:272 Mol_id: 1; Molecule: Subtilisin Bpn'; Chain: Null; Synonym: Subtilisin Novo; Ec: 3.4.21.62; Heterogen: Phenyl Methyl Sulfonate (Bacillus sp.)
- gi|349932|pdb|2SIC|E Chain E, Subtilisin BPN' (E.C.3.4.21.14) Complex With Streptomyces Subtilisin Inhibitor (Bacillus amyloliquefaciens)
- gi|494884|pdb|3SIC|E Chain E, Subtilisin Bpn' (E.C.3.4.21.62) Complex With A Modified Ssi (Streptomyces Subtilisin Inhibitor) Where Met 73 Was Replaced By Lys (Ssi(M73k)) (Bacillus amyloliquefaciens)
- gi|230752|pdb|2ST1| Subtilisin BPN' (BAS) (E.C.3.4.21.14) (Bacillus amyloliquefaciens)
- gi|230336|pdb|1ST2| Subtilisin BPN' (BASox) - Peroxide Inactivated (E.C.3.4.21.14) (Bacillus amyloliquefaciens)
- gi|494578|pdb|1SBN|E Chain E, Subtilisin Novo Bpn' (E.C.3.4.21.62) Complex With Eglin C Mutant With Leu 45 Replaced By Arg (L45r) (Bacillus subtilis)
- gi|494916|pdb|5SIC|E Chain E, Subtilisin Bpn' (E.C.3.4.21.62) Complex With Streptomyces Subtilisin Inhibitor Mutant With Met 70 Replaced By Gly And Met 73 Replaced By Lys (Ssi(M70g,M73k)) (Bacillus amyloliquefaciens)
- gi|443266|pdb|1SIB|E Chain E, Subtilisin Novo (Bpn') (E.C.3.4.21.62) Complex With Eglin C Mutant With Arg 53 Replaced By Lys (R53k) (Bacillus subtilis)
- gi|230743|pdb|2SNI|E_48:272 Chain E, Subtilisin Novo (E.C.3.4.21.14) Complex With Chymotrypsin Inhibitor 2 (CI-2) (Bacillus amyloliquefaciens)
- gi|1310968|pdb|1SBH|_48:272 Subtilisin Bpn' 8397+1 (E.C. 3.4.21.14) Mutant (M50f, N76d, G169a, Q206c, N218s, K256y) (Bacillus amyloliquefaciens)
- gi|1633075|pdb|1YJA| Subtilisin Bpn' 8397+1 (E.C. 3.4.21.14) (Mutant With Met 50 Replaced By Phe, Asn 76 Replaced By Asp, Gly 169 Replaced By Ala, Gln 206 Replaced By Cys, Asn 218 Replaced By Ser And Lys 256 Replaced By Tyr) (M50f, N76d, G169a, Q206c, N218s, And K256y) In > (Bacillus amyloliquefaciens)
- gi|1633074|pdb|1YJB| Subtilisin Bpn' 8397+1 (E.C. 3.4.21.14) (Mutant With Met 50 Replaced By Phe, Asn 76 Replaced By Asp, Gly 169 Replaced By Ala, Gln 206 Replaced By Cys, Asn 218 Replaced By Ser And Lys 256 Replaced By Tyr) (M50f, N76d, G169a, Q206c, N218s, And K256y) In > (Bacillus amyloliquefaciens)
- gi|1633073|pdb|1YJC| Subtilisin Bpn' 8397+1 (E.C. 3.4.21.14) (Mutant With Met 50 Replaced By Phe, Asn 76 Replaced By Asp, Gly 169 Replaced By Ala, Gln 206 Replaced By Cys, Asn 218 Replaced By Ser And Lys 256 Replaced By Tyr) (M50f, N76d, G169a, Q206c, N218s, And K256y) In > (Bacillus amyloliquefaciens)
- gi|1310967|pdb|1SBI|_48:272 Subtilisin Bpn' 8397 (E.C. 3.4.21.14) Mutant (M50f, N76d, G169a, Q206c, N218s) (Bacillus amyloliquefaciens)
- gi|2624593|pdb|1AK9|_48:272 Subtilisin Mutant 8321 (Bacillus amyloliquefaciens)
- gi|230314|pdb|1S01|_48:272 Subtilisin BPN(Prime) 8350 (E.C.3.4.21.14) (Mutant With Met 50 Replaced By Phe, Asn 76 Replaced By Asp, Gly 169 Replaced By Ala, Gln 206 Replaced By Cys, Tyr 217 Replaced By Lys, And Asn 217 Replaced By Ser) (M50F, N76D, G169A, Q206C, Y217K, And N218S)> (Bacillus amyloliquefaciens)
- gi|135017|sp|P07518|SUBT_BACPU_48:272 SUBTILISIN (ALKALINE MESENTERICOPEPTIDASE) (Bacillus pumilus)
- gi|224890|prf||1203267A mesentericopeptidase,alkaline [Bacillus pumilus] (Bacillus pumilus)
- gi|2914658|pdb|1AQN|_48:272 Subtilisin Mutant 8324 (Bacillus amyloliquefaciens)
- gi|2780869|pdb|1AU9| Subtilisin Bpn' Mutant 8324 In Citrate (Bacillus amyloliquefaciens)
- gi|230315|pdb|1S02|_48:271 Subtilisn Bpn' (E.C.3.4.21.14) (Mutant With Gln 19 Replaced By Glu, Gln 271 Replaced By Glu) (Q19E,Q271E) (Bacillus amyloliquefaciens)
- gi|230163|pdb|1MEE|A_48:272 Chain A, Mesentericopeptidase (E.C.3.4.21.14) Peptidyl Peptide Hydrolase Complex With Eglin-C (Bacillus pumilus)
- gi|4139636|pdb|1SCJ|A_48:272 Chain A, Crystal Structure Of Subtilisin-Propeptide Complex (Bacillus subtilis)
- gi|3986320|dbj|BAA35011.1|_48:272 (AB020503) lytic enzyme L27 [Bacillus subtilis] (Bacillus subtilis)
- gi|549004|sp|P35835|SUBN_BACNA_154:378 SUBTILISIN NAT PRECURSOR (Bacillus subtilis var. natto)
- gi|322200|pir||JH0778 subtilisin (EC 3.4.21.62) NAT precursor - Bacillus subtilis (strain natto NC2-1) (Bacillus subtilis)
- gi|262757|gb|AAC60424.1| (S51909) subtilisin NAT=serine proteinase [Bacillus subtilis, natto, NC2-1, Peptide, 381 aa] (Bacillus subtilis)
- gi|435440|dbj|BAA04989.1| (D25319) subtilisin [Bacillus subtilis] (Bacillus subtilis)
- gi|383380|prf||1903156A subtilisin:ISOTYPE=NAT [Bacillus subtilis] (Bacillus subtilis)
- gi|135019|sp|P00783|SUBT_BACSA_154:378 SUBTILISIN AMYLOSACCHARITICUS PRECURSOR (Bacillus subtilis var. amylosacchariticus)
- gi|1070498|pir||SUBSS subtilisin (EC 3.4.21.62) amylosacchariticus precursor - Bacillus subtilis (Bacillus subtilis)
- gi|912425|dbj|BAA00186.1| (D00264) subtilisin amylosacchariticus precursor [Bacillus subtilis] (Bacillus subtilis)
- gi|135021|sp|P29142|SUBT_BACST_154:378 SUBTILISIN J PRECURSOR (Bacillus stearothermophilus)
- gi|80227|pir||JQ1487 subtilisin (EC 3.4.21.62) J precursor - Bacillus stearothermophilus (Bacillus stearothermophilus)
- gi|142532|gb|AAA22247.1| (M64743) subtilisin J [Bacillus stearothermophilus] (Bacillus stearothermophilus)
- gi|6980850|pdb|1DUI|A_48:263 Chain A, Subtilisin Bpn' From Bacillus Amyloliquefaciens, Crystal Growth Mutant (Bacillus amyloliquefaciens)
- gi|230319|pdb|1SBT|_48:272 Subtilisin BPN (E.C.3.4.21.14) (Bacillus amyloliquefaciens)
- gi|1311236|pdb|1SPB|S_48:263 Chain S, Subtilisin Bpn' Prosegment (77 Residues) Complexed With A Mutant Subtilisin Bpn' (266 Residues). Crystal Ph 4.6. Crystallization Temperature 20 C Diffraction Temperature -160 C (Bacillus sp.)
- gi|3891860|pdb|1SUE|_48:262 Subtilisin Bpn' From Bacillus Amyloliquefaciens, Mutant (Bacillus amyloliquefaciens)
- gi|361357|prf||1408206A_154:378 subtilisin amylosacchariticus gene [Bacillus subtilis] (Bacillus subtilis)
- gi|135022|sp|P04189|SUBT_BACSU_154:378 SUBTILISIN E PRECURSOR (Bacillus subtilis)
- gi|67622|pir||SUBSI subtilisin (EC 3.4.21.62) E precursor - Bacillus subtilis (Bacillus subtilis)
- gi|143520|gb|AAA22742.1| (K01988) subtilisin (gtg start codon) [Bacillus subtilis] (Bacillus subtilis)
- gi|2226248|emb|CAA74536.1|_154:378 (Y14083) subtilisin E precursor [Bacillus subtilis] (Bacillus subtilis)
- gi|2633366|emb|CAB12870.1| (Z99109) serine alkaline protease (subtilisin E) [Bacillus subtilis] (Bacillus subtilis)
- gi|2914616|pdb|1SUA|A_48:262 Chain A, Subtilisin Bpn' ()
- gi|1839353|gb|AAB47045.1|_48:272 subtilisin=thermostable serine protease/thermostable mesentericopeptidase homolog [Bacillus subtilis, RT-5, Pakistani Tharparkar desert soil isolate, Peptide, 275 aa] (Bacillus subtilis)
- gi|1421200|pdb|2SBT|_48:271 Subtilisin Novo (E.C.3.4.21.14) (Bacillus amyloliquefaciens)
- gi|80421|pir||A23624_48:270 subtilisin (EC 3.4.21.62) BM - Bacillus sp (Bacillus sp.)
- gi|640400|pdb|1SCN|E_58:271 Chain E, Subtilisin Carlsberg (E.C.3.4.21.62) Complexed With N-(Tert-Butoxycarbonyl-Alanyl-Prolyl-Phenylalanyl)- O-Benzoyl Hydroxylamine (Bacillus licheniformis)
- gi|3891521|pdb|1BH6|A_52:270 Chain A, Subtilisin Dy In Complex With The Synthetic Inhibitor N-Benzyloxycarbonyl-Ala-Pro-Phe-Chloromethyl Ketone (Bacillus licheniformis)
- gi|229772|pdb|1CSE|E_58:270 Chain E, Subtilisin Carlsberg (E.C.3.4.21.62) (Commercial Product From Serra, Heidelberg Called Subtilisin Nagarse) Complex With Eglin-C (Bacillus subtilis)
- gi|230739|pdb|2SEC|E Chain E, Subtilisin Carlsberg (E.C.3.4.21.62) Complex With Genetically-Engineered N-Acetyl Eglin-C (Bacillus subtilis)
- gi|494580|pdb|1SCA| Subtilisin Carlsberg (E.C.3.4.21.62) (Aqueous Form) (Bacillus licheniformis)
- gi|3891950|pdb|1BE6| Trans-Cinnamoyl-Subtilisin In Anhydrous Acetonitrile (Bacillus licheniformis)
- gi|3891616|pdb|1BE8| Trans-Cinnamoyl-Subtilisin In Water (Bacillus licheniformis)
- gi|3891619|pdb|1BFU| Subtilisin Carlsberg In 20% Dioxane (Bacillus licheniformis)
- gi|494581|pdb|1SCB| Subtilisin Carlsberg (E.C.3.4.21.62) (Acetonitrile Soaked Crystals) (Bacillus licheniformis)
- gi|3891617|pdb|1BFK| Crystal Structure Of Subtilisin Carlsberg In 40% Acetonitrile (Bacillus licheniformis)
- gi|494582|pdb|1SCD| Subtilisin Carlsberg (E.C.3.4.21.62) (Bacillus licheniformis)
- gi|230318|pdb|1SBC| Subtilisin Carlsberg (Subtilopeptidase A) (E.C.3.4.21.62) (Bacillus subtilis)
- gi|2392083|pdb|1AF4| Crystal Structure Of Subtilisin Carlsberg In Anhydrous Dioxane (Bacillus licheniformis)
- gi|443257|pdb|1SEL|A_58:270 Chain A, Selenosubtilisin (Chemically Engineered Mutant With Ser 221 Replaced By Selenocysteine) (Bacillus subtilis)
- gi|443258|pdb|1SEL|B Chain B, Selenosubtilisin (Chemically Engineered Mutant With Ser 221 Replaced By Selenocysteine) (Bacillus subtilis)
- gi|3114539|pdb|1AVT| Subtilisin Carlsberg D-Para-Chlorophenyl-1-Acetamido Boronic Acid Inhibitor Complex (Bacillus licheniformis)
- gi|2981821|pdb|1VSB| Subtilisin Carlsberg L-Para-Chlorophenyl-1-Acetamido Boronic Acid Inhibitor Complex (Bacillus licheniformis)
- gi|3114483|pdb|1AV7| Subtilisin Carlsberg L-Naphthyl-1-Acetamido Boronic Acid Inhibitor Complex (Bacillus licheniformis)
- gi|3114519|pdb|3VSB| Subtilisin Carlsberg D-Naphthyl-1-Acetamido Boronic Acid Inhibitor Complex (Bacillus licheniformis)
- gi|4139475|pdb|1A1Y|E_58:270 Chain E, Alcalase (Subtilisin Carlsberg Variant) In Complex With Chymotrypsin Inhibitor Ci-2a (Bacillus licheniformis)
- gi|4139472|pdb|1A10|E Chain E, Alcalase (Subtilisin Carlsberg Variant) In Complex With Chymotrypsin Inhibitor Ci-2a(M59p) (Bacillus licheniformis)
- gi|995621|emb|CAA62666.1|_163:375 (X91260) substilisin Carlsberg [Bacillus licheniformis] (Bacillus licheniformis)
- gi|2145514|pir||JC4900_235:625 xanthomonapepsin (EC 3.4.23.33) - Xanthomonas sp (Xanthomonas sp.)
- gi|1217603|dbj|BAA12093.1| (D83740) carboxyl proteinase precursor [Xanthomonas sp.] (Xanthomonas sp.)
- gi|6753448|ref|NP_034036.1|_249:555 ceroid-lipofuscinosis, neuronal 2 (Mus musculus)
- gi|4106913|gb|AAD03083.1| (AF111172) lysosomal pepstatin insensitive protease precursor [Mus musculus] (Mus musculus)
- gi|4894649|gb|AAD32573.1|AF124599_1 (AF124599) lysosomal pepstatin-insensitive protease [Mus musculus] (Mus musculus)
- gi|6175068|sp|O14773|TPP1_HUMAN_249:556 TRIPEPTIDYL-PEPTIDASE I PRECURSOR (TRIPEPTIDYL AMINOPEPTIDASE) (LYSOSOMAL PEPSTATIN INSENSITIVE PROTEASE) (LPIC) (Homo sapiens)
- gi|2408232|gb|AAB80725.1| (AF017456) lysosomal pepstatin insensitive protease [Homo sapiens] (Homo sapiens)
- gi|5821945|pdb|1C3L|A_58:270 Chain A, Subtilisin-Carlsberg Complexed With Xenon (8 Bar) (Bacillus licheniformis)
- gi|5729770|ref|NP_000382.3|_249:556 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) (Homo sapiens)
- gi|4063841|gb|AAC98480.1| (AF039704) lysosomal pepstatin insensitive protease [Homo sapiens] (Homo sapiens)
- gi|6094507|sp|O89023|TPP1_MOUSE_220:527 TRIPEPTIDYL-PEPTIDASE I PRECURSOR (TRIPEPTIDYL AMINOPEPTIDASE) (LYSOSOMAL PEPSTATIN INSENSITIVE PROTEASE) (LPIC) (Mus musculus)
- gi|3766471|emb|CAA09863.1| (AJ011912) putative tripeptidyl peptidase I [Mus musculus] (Mus musculus)
- gi|4583351|gb|AAD25043.1|AF114167_1_249:556 (AF114167) lysosomal pepstatin insensitive protease [Canis familiaris] (Canis familiaris)
- gi|1890101|gb|AAB49694.1|_176:387 (U89495) protease [Bacillus sp. PD498] (Bacillus sp. PD498)
- gi|5302815|emb|CAB46075.1|_177:427 (AJ238598) putative 36kDa protease [Bacillus sphaericus] (Bacillus sphaericus)
- gi|2731626|gb|AAB93489.1|_180:430 (U32628) toxin degrading protease [Bacillus sphaericus] (Bacillus sphaericus)
- gi|881428|gb|AAA70103.1|_165:560 (U27540) vegetative stage specific V4-7 [Dictyostelium discoideum] (Dictyostelium discoideum)
- gi|5726590|gb|AAD48483.1|AF170567_1_165:381 (AF170567) alkaline protease A [Bacillus thuringiensis] (Bacillus thuringiensis)
- gi|224028|prf||1008150A_48:252 subtilisin [Bacillus pumilus] (Bacillus pumilus)
- gi|135018|sp|P28842|SUBT_BACS9_168:416 SUBTILISIN PRECURSOR (Bacillus sp. TA39)
- gi|80172|pir||S23407 subtilisin (EC 3.4.21.62) 1 precursor - Bacillus sp. (strain TA39) (Bacillus sp.)
- gi|40201|emb|CAA44227.1| (X62369) microbial serine proteinases [Bacillus sp.] (Bacillus sp.)
- gi|7435650|pir||JW0075_165:381 cysteine-dependent serine proteinase (EC 3.4.21.-) precursor - Bacillus cereus (Bacillus cereus)
- gi|5002190|gb|AAD37351.1|_5:357 (AF142414) pepstatin-insensitive carboxyl proteinase 1 [Amoeba proteus] (Amoeba proteus)
- gi|576815|gb|AAA80562.1|_221:466 (L37754) serine protease [Dichelobacter nodosus] (Dichelobacter nodosus)
- gi|545060|gb|AAC60459.1|_181:392 (S68495) alkaline serine protease II, AprII [Alteromonas, O-7, Peptide, 621 aa] (Alteromonas)
- gi|2344767|dbj|BAA21890.1| (D14537) pre-pro-AprII [Alteromonas sp.] (Alteromonas sp.)
- gi|740000|prf||2004286A alkaline Ser protease [Alteromonas sp.] (Alteromonas sp.)
- gi|742825|prf||2011184A_163:372 alkaline phosphatase [Fusarium sp.] (Fusarium sp.)
- gi|7435653|pir||H72784_186:432 probable alkaline proteinase APE0263 - Aeropyrum pernix (strain K1) (Aeropyrum pernix)
- gi|5103657|dbj|BAA79178.1| (AP000058) 440aa long hypothetical alkaline protease [Aeropyrum pernix] (Aeropyrum pernix)
- gi|628051|pir||JC2142_163:372 alkaline proteinase (EC 3.4.21.-) precursor - fungus (Fusarium sp.) (strain S-19-5) (Fusarium sp.)
- gi|7705202|gb|AAC60571.2| (S71812) alkaline protease; Alp [Fusarium sp.] (Fusarium sp.)
- gi|323087|pir||A44869_33:350 cell type-specific protein php - slime mold (Physarum polycephalum) (Physarum polycephalum)
- gi|895878|emb|CAA45964.1| (X64708) PHP [Physarum polycephalum] (Physarum polycephalum)
- gi|6624958|emb|CAB63911.1|_172:383 (AJ251925) Subtilisin-like serine protease PR1A [Metarhizium anisopliae var. acridum] (Metarhizium anisopliae var. acridum)
- gi|494645|pdb|1THM|_59:269 Thermitase (E.C.3.4.21.66) (Thermoactinomyces vulgaris)
- gi|117631|sp|P29138|CUDP_METAN_172:383 CUTICLE-DEGRADING PROTEASE PRECURSOR (PR1) (CHYMOELASTASE) (Metarhizium anisopliae)
- gi|283401|pir||S22387 cuticle-degrading proteinase (EC 3.4.21.-) precursor - imperfect fungus (Metarhizium anisopliae) (Metarhizium anisopliae)
- gi|168343|gb|AAA33417.1| (M73795) cuticle-degrading protease [Metarhizium anisopliae] (Metarhizium anisopliae)
- gi|6573500|pdb|1DBI|A_60:270 Chain A, Crystal Structure Of A Thermostable Serine Protease (Bacillus sp.)
- gi|135738|sp|P04072|THET_THEVU_59:269 THERMITASE (Thermoactinomyces vulgaris)
- gi|67623|pir||SUMYTV thermitase (EC 3.4.21.66) - Thermoactinomyces vulgaris (Thermoactinomyces vulgaris)
- gi|230758|pdb|2TEC|E Chain E, Thermitase (E.C.3.4.21.14) Complex With Eglin-C (5 Millimolar Calcium) (Thermoactinomyces vulgaris)
- gi|230927|pdb|3TEC|E Chain E, Thermitase (E.C.3.4.21.14) Complex With Eglin-C (100 Millimolar Calcium) (Thermoactinomyces vulgaris)
- gi|230344|pdb|1TEC|E Chain E, Thermitase (E.C.3.4.21.14) Complex With Eglin-C (Thermoactinomyces vulgaris)
- gi|224450|prf||1105242A thermitase [Thermoactinomyces vulgaris] (Thermoactinomyces vulgaris)
- gi|2118106|pir||I39974_181:391 serine proteinase - Bacillus sp (Bacillus sp.)
- gi|529980|gb|AAA63688.1| (L29506) serine proteinase [Bacillus sp.] (Bacillus sp.)
- gi|2127250|pir||S68012_42:209 subtilisin (EC 3.4.21.62) - Bacillus subtilis (fragment) (Bacillus subtilis)
- gi|282432|pir||S25835_170:415 subtilisin (EC 3.4.21.62) precursor - Bacillus sp. (strain TA41) (Bacillus sp.)
- gi|40199|emb|CAA45096.1| (X63533) microbial serine proteinases [Bacillus subtilis] (Bacillus subtilis)
- gi|746256|prf||2017292A subtilisin:ISOTYPE=S41 [Bacillus sp.] (Bacillus sp.)
- gi|1168687|sp|P42779|BPRV_BACNO_221:466 EXTRACELLULAR BASIC PROTEASE PRECURSOR (Dichelobacter nodosus)
- gi|282153|pir||S27055 basic serine proteinase (EC 3.4.21.-) precursor - Dichelobacter nodosus (Dichelobacter nodosus)
- gi|40818|emb|CAA78894.1| (Z16080) basic protease [Dichelobacter nodosus] (Dichelobacter nodosus)
- gi|2921857|gb|AAC04871.1|_204:571 (AF047370) extracellular alkaline serine protease [Shewanella sp. Ac10] (Shewanella sp. Ac10)
- gi|460032|gb|AAA91584.1|_148:358 (L29262) serine protease [Paecilomyces lilacinus] (Paecilomyces lilacinus)
- gi|732988|emb|CAA82213.1|_181:534 (Z28354) alkaline serine protease (VapT) [Vibrio metschnikovii] (Vibrio metschnikovii)
- gi|7484206|pir||S73083_240:593 hypothetical protein c0616 - Sulfolobus solfataricus (Sulfolobus solfataricus)
- gi|1707695|emb|CAA69499.1| (Y08256) orf c06016 [Sulfolobus solfataricus] (Sulfolobus solfataricus)
- gi|130965|sp|P23314|PROA_XANCP_230:465 EXTRACELLULAR PROTEASE PRECURSOR (Xanthomonas campestris pv. campestris)
- gi|95022|pir||S11890 serine proteinase (EC 3.4.21.-) precursor, extracellular - Xanthomonas campestris pv. campestris (Xanthomonas campestris pv. campestris)
- gi|48534|emb|CAA35962.1| (X51635) protease [Xanthomonas campestris] (Xanthomonas campestris)
- gi|7481372|pir||T36842_94:323 probable secreted serine proteinase SCI35.29c - Streptomyces coelicolor (Streptomyces coelicolor)
- gi|3581862|emb|CAA20818.1| (AL031541) putative secreted serine protease [Streptomyces coelicolor A3(2)] (Streptomyces coelicolor A3(2))
- gi|1086249|pir||S52769_202:603 subtilisin-like proteinase ag12 (EC 3.4.21.-) - Alnus glutinosa (Alnus glutinosa)
- gi|757522|emb|CAA59964.1| (X85975) subtilisin-like protease [Alnus glutinosa] (Alnus glutinosa)
- gi|6634475|emb|CAB64346.1|_171:368 (AJ251972) subtilisin-like protease PR1I [Metarhizium anisopliae var. anisopliae] (Metarhizium anisopliae var. anisopliae)
- gi|6624962|emb|CAB63913.1|_212:450 (AJ251965) subtilisin-like protease PR1H [Metarhizium anisopliae var. anisopliae] (Metarhizium anisopliae var. anisopliae)
- gi|6624950|emb|CAB63907.1|_212:450 (AJ251921) Subtilisin-like protease PR1H [Metarhizium anisopliae var. anisopliae] (Metarhizium anisopliae var. anisopliae)
- gi|131088|sp|P20015|PRTT_TRIAL_75:261 PROTEINASE T PRECURSOR (Tritirachium album)
- gi|83957|pir||JQ0380 proteinase T (EC 3.4.21.-) - imperfect fungus (Tritirachium album) (fragment) (Tritirachium album)
- gi|170527|gb|AAA34204.1| (M54900) proteinase [Tritirachium album] (Tritirachium album)
- gi|170529|gb|AAA34205.1| (M54901) proteinase [Tritirachium album] (Tritirachium album)
- gi|135023|sp|P29141|SUBV_BACSU_211:572 MINOR EXTRACELLULAR PROTEASE VPR PRECURSOR (Bacillus subtilis)
- gi|80335|pir||A41341 microbial serine proteinase (EC 3.4.21.-), minor (vpr), precursor - Bacillus subtilis (Bacillus subtilis)
- gi|143820|gb|AAA22881.1| (M76590) minor serine extracellular protease [Bacillus subtilis] (Bacillus subtilis)
- gi|580871|emb|CAA51601.1| (X73124) ipa-45r vpr [Bacillus subtilis] (Bacillus subtilis)
- gi|2636344|emb|CAB15835.1| (Z99123) extracellular serine protease [Bacillus subtilis] (Bacillus subtilis)
- gi|4761119|gb|AAD29255.1|AF104385_1_163:372 (AF104385) cuticle-degrading protease bassiasin I precursor [Beauveria bassiana] (Beauveria bassiana)
- gi|7473895|pir||A75589_239:445 serine proteinase, subtilase family - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6460736|gb|AAF12441.1|AE001863_66 (AE001863) serine protease, subtilase family [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|7595970|gb|AAF64521.1|AF253471_1_129:445 (AF253471) extracellular serine protease [Aeromonas sobria] (Aeromonas sobria)
- gi|3549630|emb|CAA75805.1|_123:310 (Y15872) alkaline protease [Aspergillus fumigatus] (Aspergillus fumigatus)
- gi|2127379|pir||JC6032_274:682 cell surface proteinase (EC 3.4.-.-) precursor - Lactobacillus delbrueckii subsp. bulgaricus (Lactobacillus delbrueckii subsp. bulgaricus)
- gi|1381114|gb|AAC41529.1| (L48487) proteinase precursor [Lactobacillus delbrueckii] (Lactobacillus delbrueckii)
- gi|470731|gb|AAA67705.1|_185:379 (L31778) alkaline protease [Aspergillus nidulellus] (Aspergillus nidulellus)
- gi|129234|sp|P28296|ORYZ_ASPFU_184:372 ORYZIN PRECURSOR (ALKALINE PROTEINASE) (ALP) (ELASTASE) (ELASTINOLYTIC SERINE PROTEINASE) (Aspergillus fumigatus)
- gi|101826|pir||S22184 serine proteinase alp (EC 3.4.21.-) - Aspergillus fumigatus (Aspergillus fumigatus)
- gi|2295|emb|CAA77666.1| (Z11580) uncleaved alkaline protease (ALP) [Aspergillus fumigatus] (Aspergillus fumigatus)
- gi|7542318|gb|AAF63395.1|AF083618_2_199:466 (AF083618) putative serine protease [Xanthomonas campestris pv. pelargonii] (Xanthomonas campestris pv. pelargonii)
- gi|384177|prf||1905286A_184:372 extracellular alkaline protease [Aspergillus fumigatus] (Aspergillus fumigatus)
- gi|2239272|gb|AAB62277.1|_225:438 (L76740) protease [Epichloe typhina] (Epichloe typhina)
- gi|5918763|gb|AAD56147.1|AF154675_7_173:429 (AF154675) MutP [Streptococcus mutans] (Streptococcus mutans)
- gi|7414560|emb|CAB86111.1|_251:481 (AL163003) putative secreted peptidase [Streptomyces coelicolor A3(2)] (Streptomyces coelicolor A3(2))
- gi|7473900|pir||F75625_232:478 serine proteinase, subtilase family - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6460889|gb|AAF12593.1|AE001826_62 (AE001826) serine protease, subtilase family [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|4115628|dbj|BAA36466.1|_113:359 (AB015053) serine protease homologue [Pseudomonas fluorescens] (Pseudomonas fluorescens)
- gi|113482|sp|P09230|AEP_YARLI_225:431 ALKALINE EXTRACELLULAR PROTEASE PRECURSOR (AEP) (Yarrowia lipolytica)
- gi|83636|pir||A26955 alkaline serine proteinase (EC 3.4.21.-) precursor - yeast (Yarrowia lipolytica) (Yarrowia lipolytica)
- gi|173244|gb|AAA35242.1| (M17741) alkaline extracellular protease precursor [Yarrowia lipolytica] (Yarrowia lipolytica)
- gi|173265|gb|AAA35250.1| (M23353) alkaline extracellular protease precursor [Yarrowia lipolytica] (Yarrowia lipolytica)
- gi|7481387|pir||T10926_89:322 probable serine proteinase (EC 3.4.21.-), secreted - Streptomyces coelicolor (Streptomyces coelicolor)
- gi|3413405|emb|CAA20266.1| (AL031231) putative secreted serine protease [Streptomyces coelicolor A3(2)] (Streptomyces coelicolor A3(2))
- gi|7473898|pir||D75393_205:429 serine proteinase, subtilase family - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6459217|gb|AAF11026.1|AE001990_3 (AE001990) serine protease, subtilase family [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|3646417|emb|CAA07702.1|_113:359 (AJ007828) serine protease [Pseudomonas tolaasii] (Pseudomonas tolaasii)
- gi|7473893|pir||A75474_217:583 serine proteinase, subtilase family - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6458525|gb|AAF10389.1|AE001935_8 (AE001935) serine protease, subtilase family [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|125348|sp|P09231|KEX1_KLULA_198:444 KEX1 PROTEASE PRECURSOR (Kluyveromyces lactis)
- gi|82866|pir||S01013 kexin (EC 3.4.21.61) 1 precursor - yeast (Kluyveromyces marxianus var. lactis) (Kluyveromyces lactis)
- gi|2835|emb|CAA30088.1| (X07038) kex1 protein [Kluyveromyces lactis] (Kluyveromyces lactis)
- gi|3334242|sp|O13359|KEX2_CANAL_247:491 KEXIN PRECURSOR (KEX2 PROTEASE) (Candida albicans)
- gi|2511732|gb|AAB80929.1| (AF022372) proteinase [Candida albicans] (Candida albicans)
- gi|5002192|gb|AAD37352.1|AF142415_1_256:482 (AF142415) pepstatin-insensitive carboxyl proteinase 2 [Amoeba proteus] (Amoeba proteus)
- gi|7473901|pir||D75286_10:170 serine proteinase, subtilase family, C-terminal fragment - Deinococcus radiodurans (strain R1) (Deinococcus radiodurans)
- gi|6460135|gb|AAF11870.1|AE002064_1 (AE002064) serine protease, subtilase family, C-terminal fragment [Deinococcus radiodurans] (Deinococcus radiodurans)
- gi|2293484|gb|AAB65414.1|_1:200 (AF010468) serine protease [Dermatophilus congolensis] (Dermatophilus congolensis)
- gi|283589|pir||S27270_223:473 prohormone convertase LPC2 - great pond snail (Lymnaea stagnalis)
- gi|312577|emb|CAA48730.1| (X68850) LPC2 [Lymnaea stagnalis] (Lymnaea stagnalis)
- gi|4835715|gb|AAD30204.1|AF064522_1_163:264 (AF064522) major autolysin [Moraxella sp. CK-1] (Moraxella sp. CK-1)
- gi|542504|pir||S40449_223:474 pro-hormone convertase PC2 precursor - California sea hare (Aplysia californica)
- gi|430855|gb|AAA03496.1| (L22986) hormone convertase 2 [Aplysia californica] (Aplysia californica)
- gi|558493|gb|AAA66497.1| (L34741) prohormone convertase [Aplysia californica] (Aplysia californica)
- gi|480411|pir||S36823_223:474 convertase PC2 precursor - California sea hare (Aplysia californica)
- gi|416483|emb|CAA42204.1| (X59682) prepro-hormone convertase 2 [Aplysia californica] (Aplysia californica)
- gi|453663|gb|AAA27769.1|_223:474 (L28768) PC2 [Aplysia californica] (Aplysia californica)

              10           20             30        40             50  
              |            |              |         |              |  
   1 AAGTAKGHNPTEFPT...IYDASSAPTAA.....NTTVGIITIGGVSQTLQDLQQF.....TSAN
   2 AAGTAKGHNPTEFPT...IYDASSAPTAA.....NTTVGIITIGGVSQTLQDLQQF.....TSAN
   3 AAGTAKGHNPTEFPT...IYDASSAPTAA.....NTTVGIITIGGVSQTLQDLQQF.....TSAN
   4 ASMVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
   5 ASMVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
   6 ASFVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
   7 ASMVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
   8 ASMVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
   9 ASMVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
  10 ASMVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
  11 ASMVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
  12 ASFVPSETNPFQDNN...SHGTHVAGTVAal...DNSIGVL---------------.....---G
  13 ASFVPSETNPFQDNN...SHGTHVAGTVAal...DNSIGVL---------------.....---G
  14 ASFVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
  15 ASFVPSETNPFQDNN...SHGTHVAGTVAal...DNSIGVL---------------.....---G
  16 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  17 ASFVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
  18 ASMVPSETNPFQDNN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
  19 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  20 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  21 ASMVPSETNPFQDYN...SHGTHVAGTVAal...NNSVGVL---------------.....---G
  22 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  23 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  24 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  25 ASFVPSETNPFQDNN...SHGTHVAGTVL.....----------------------.....---A
  26 ASMVPSETPNFQDDN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
  27 ASFVPSETNPFQDNN...SHGTHVAGTVL.....----------------------.....---A
  28 ASFVPSETNPFQDNN...SHGTHVAGTVL.....----------------------.....---A
  29 ASFVPSETNPYQDGS...SHGTHVAGYIAal...NNSIGVL---------------.....---G
  30 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  31 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  32 ASFVPSETNPFQDNN...SHGTHVAGTVL.....----------------------.....---A
  33 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  34 ASMVPSETPNFQDDN...SHGTHVAGTVAal...NNSIGVL---------------.....---G
  35 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  36 -----------TDGN...GHGTHVAGTVAal...DNTTGVL---------------.....---G
  37 -----SGESYNTDGN...GHGTHVAGTVAal...DNTTGVL---------------.....---G
  38 -----------TDGN...GHGTHVAGTVAal...DNTTGVL---------------.....---G
  39 -----------TDGN...GHGTHVAGTVAal...DNTTGVL---------------.....---G
  40 -----------TDGN...GHGTHVAGTVAal...DNTTGVL---------------.....---G
  41 -----------TDGN...GHGTHVAGTVAal...DNTTGVL---------------.....---G
  42 AAAAVAAHHPQDFAA...IYGGSSLPAAT.....NTAVGIITWGSITQTVTDLNSF.....TSGA
  43 -------------SF...THQASVAKVVGkqg..RGRAGIE-------ASLDVEYL.....MSAG
  44 ------------GNF...AHQASVARVVGqqg..RGRAGIE-------ASLDVQYL.....MSAG
  45 -----------TDGN...GHGTHVAGTVAal...DNTTGVL---------------.....---G
  46 ------------GNF...AHQASVARVVGqqg..RGRAGIE-------ASLDVQYL.....MSAG
  47 -------------SF...THQASVAKVVGkqg..RGRAGIE-------ASLDVEYL.....MSAG
  48 ------------GNF...AHQASVARVVGqqg..RGRAGIE-------ASLDVEYL.....MSAG
  49 ---FIDRDNNPMDLN...GHGTHVAGTVAadt..NNGIGVA---------------.....---G
  50 -GATTPINNSCTDRN...GHGTHVAGTALadgg.SDQAGIY---------------.....---G
  51 -GATTPINNSCTDRN...GHGTHVAGTALadgg.SDQAGIY---------------.....---G
  52 WATAIQQYNPIPKIA...SISYGWAEVEQce6nsCSTLGIDSVVYVARSNVELQKVg10vsSGDD
  53 --DYVDNDNTSDDGN...GHGTHCAGITGalt..NNSVGIA---------------.....---G
  54 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  55 --GTTYTNNSCTDRQ...GHGTHVAGSALadg..GTGNGVY---------------.....---G
  56 --DYVDNDNTSDDGN...GHGTHCAGITGalt..NNSVGIA---------------.....---G
  57 ---------------...-------PVTG.....NSSVGVIEFEDQNFAPSDLSDF.....ATSF
  58 CGGYPDPRREKRFST...WHGSHVAGTIAavt..NNGVGVA---------------.....---G
  59 ---FVDNDNDATDCN...GHGTHVAGTIG.....GGEYGVA---------------.....----
  60 ---------TARDGN...GHGTHCSGTIG.....SKTYGVA---------------.....----
  61 --------SNYQDRN...GHGTHVTGTVAai...DNDIGVI---------------.....---G
  62 ---------TARDGN...GHGTHCSGTIG.....SKTYGVA---------------.....----
  63 PAVTTQPFNPTVDVLplyGIDTSDSNRGA.....GQVIGIIDAYGASTAESDLAAF.....SRAN
  64 ---------QNRDGH...GHGTHCAGTIG.....SRSYGVA---------------.....----
  65 ----VDNDSTPQNGN...GHGTHCAGIAAavt..NNSTGIA---------------.....---G
  66 ---------QNTDGH...GHGTHCAGTIG.....SKTYGVA---------------.....----
  67 ----VDNDYDPMDLN...NHGTHVAGIAAaet..NNATGIA---------------.....---G
  68 ----VDNDSTPQNGN...GHGTHCAGIAAavt..NNSTGIA---------------.....---G
  69 ----VDNDYDPMDLN...NHGTHVAGIAAaet..NNATGIA---------------.....---G
  70 ASFVPSETNPYQDGS...SHGTHVAGTIAal...NNSIGVL---------------.....---G
  71 -----FTDNSCTDRQ...GHGTHVAGSALang..GTGSGVY---------------.....---G
  72 CGGYPDPRREKKFST...WHGSHVAGTIAavt..NNGVGVA---------------.....---G
  73 ------------NNN...AHGTHVAGTIAai...ANNEGVV---------------.....---G
  74 ---------QNTDGN...GHGTHCAGTIG.....SKTYGVA---------------.....----
  75 -------------NN...AHGTHVAGTIAai...ANNEGVK---------------.....---G
  76 ------------FNF...TLAYERGYTGG.....GSNIAIEGVPESFVNVSDIYSF.....WQLY
  77 ---------PAASSS...WHGTHVAGTVAavt..NNTTGVA---------------.....---G
  78 -----------RSWA...RHGTAMAGIIAgh6gsGDAEGVM---------------.....---G
  79 --NATFSMNSARDTL...GHGTHTASTAA.....GNYVNGA-------SYFGYGKG.....TARG
  80 -----------SDRN...GHGTHVAGTIG.....SKKYGVA---------------.....----
  81 WGKTIPAGDADEDGN...GHGTHCSGTIA.....GKKYGVA---------------.....----
  82 WGKTIPAGDADEDGN...GHGTHCSGTIA.....GKKYGVA---------------.....----
  83 --------GQDTDGN...GHGTHVAGTVG.....GTTYGVA---------------.....----
  84 --FVDNDYDPKETPT...GDPRGEATDHG.....THVAGTVAANGTIK--------.....---G
  85 ---------GTTDGH...GHGTHCAGTIG.....SKTYGVA---------------.....----
  86 ------------GGV...GHGTAVAGIAT.....----------------------.....---Q
  87 ------DPTPTDPDT...GHGTSVSGIIAav...DNAIGTK---------------.....---G
  88 -------GGSHVDSI...GHGTHVAGTIG.....GKTYGVA---------------.....----
  89 ------------NDQ...IVDNGCGEMHG.....QHVAGIAGANGQVK--------.....---G
  90 ---------QHVDSV...GHGTHVAGTIG.....GETYGVS---------------.....----
  91 -------GGSHVDSI...GHGTHVAGTIG.....GKTYGVA---------------.....----
  92 --GECGIFSAARDSS...WHGTHVAGTIAeat..GNAIGGA---------------.....---G
  93 -------GGSHVDSI...GHGTHVAGTIG.....GKTTGVA---------------.....----
  94 ---------SNVDDN...GHGTHVAGTIG.....SRTYGVA---------------.....----
  95 ----TGSINDIDDKK...GHGTAVAGQIAan...----------GQIF--------.....---G
  96 --------EEVADRH...GHGTHVTSTVG.....GSGAASD--------------G.....KEKG
  97 -------DNQVDENI...EHGTAVTSTIAaa...RDGRGVV---------------.....---G
  98 ------------NND...SHGTHVTGTMGaa...RDGVGMH---------------.....---G
  99 ----------NADLL...GHGTHVAGTVG.....GKTYGVD---------------.....----
 100 -----QPGDERTDHE...GHGTGMAALIAgtgkhGSKSGAY---------------.....---G
 101 -----------HDTT...DHGTHTAGLLV.....GSKVGVA---------------.....----
 102 ------------NND...SHGTHVTGTMGaa...RDGVGMH---------------.....---G
 103 --------YQLNDVS...HHGTHVAGTVFaqy..GAGTGASGL----QSGMDA--N.....GVGG
 104 ------------KDD...YHGTRCAGEIAafr..NDICGV----------------.....---G
 105 ------------FDD...YHGTRCAGEIAavk..NDVCGI----------------.....---G
 106 ---------------...-----------.....----------------------.....----
 107 ---------------...-----------.....----------------------.....----
 108 ---------------...-HGTHVAGIAE.....ANMPGWK---------------.....-MQG
 109 -----------TWFN...SHGTRCAGEVSa....AKDNGVC---------------.....-GVG
 110 ---------------...-----------.....----------------------.....----
 111 -----------TWFN...SHGTRCAGEVSa....AKDNGVC---------------.....-GVG
 112 -----------TWFN...SHGTRCAGEVSa....AKDNGVC---------------.....-GVG
 113 -----------TWFN...SHGTRCAGEVSa....AKDNGVC---------------.....-GVG


              60             70           80        90         100     
              |              |            |         |           |     
   1 GLAS..VNTQT.....IQTGSSNGD.YSDDQQG..QGEWDLDSQSIVGSAGGAV..QQLLFYMA.
   2 GLAS..VNTQT.....IQTGSSNGD.YSDDQQG..QGEWDLDSQSIVGSAGGAV..QQLLFYMA.
   3 GLAS..VNTQT.....IQTGSSNGD.YSDDQQG..QGEWDLDSQSIVGSAGGAV..QQLLFYMA.
   4 VAPC..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
   5 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
   6 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
   7 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
   8 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
   9 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  10 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  11 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  12 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  13 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  14 VAPC..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  15 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  16 VAPS..SALYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  17 VAPC..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  18 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  19 VAPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  20 VSPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  21 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  22 VAPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  23 VSPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  24 VSPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  25 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  26 VAPS..SALYA.....VKVLGDAGS.GQ-----..-------------------..--------.
  27 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  28 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  29 VSPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  30 VSPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  31 VSPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  32 VAPS..ASLYA.....VKVLGADGS.GQ-----..-------------------..--------.
  33 VSPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  34 VAPS..SALYA.....VKVLGDAGS.GQ-----..-------------------..--------.
  35 VAPS..SALYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  36 VAPS..VSLYA.....VKVLNSSGS.GS-----..-------------------..--------.
  37 VAPN..VSLYA.....IKVLNSSGS.GS-----..-------------------..--------.
  38 VAPS..VSLYA.....VKVLNSSGS.GS-----..-------------------..--------.
  39 VAPS..VSLYA.....VKVLNSSGS.GS-----..-------------------..--------.
  40 VAPS..VSLYA.....VKVLNSSGS.GS-----..-------------------..--------.
  41 VAPS..VSLYA.....VKVLNSSGS.GS-----..-------------------..--------.
  42 GLAT..VNSTI.....TKVGS--GT.FANDPDS..NGEWSLDSQDIVGIAGGVK..QLIFYTSAn
  43 ANIS..TW---.....--VYSSPGR.HE-----..--------------AQEPF..LQWLLLLS.
  44 ANIS..TW---.....--VYSSPGR.HE-----..--------------GQEPF..LQWLMLLS.
  45 VAPS..VSLYA.....VKVLNSSGS.GS-----..-------------------..--------.
  46 ANIS..TW---.....--VYSSPGR.HE-----..--------------GQEPF..LQWLMLLS.
  47 ANIS..TW---.....--VYSSPGR.HE-----..--------------AQEPF..LQWLLLLS.
  48 ANIS..TW---.....--VYSSPGR.HE-----..--------------SQEPF..LQWLLLLS.
  49 MAPD..TKILA.....VRVLDANGS.GS-----..-------------------..--------.
  50 VAPD..ADLWA.....YKVLLDSGSgYSDDIAA..AIRHAADQATATGT-----..--------.
  51 VAPD..ADLWA.....YKVLLDSGSgYSDDIAA..AIRHAADQATATGT-----..--------.
  52 GAPS..FG-AA.....SGNCPIDGT.KQYCPLG..GCNHKSSQCPMITIMESNG..TQCFFPMGs
  53 VAPQ..TSIYA.....VRVLDNQGS.GT-----..-------------------..--------.
  54 VAPS..SA--L.....YKVLDSTGS.GQ-----..-------------------..--------.
  55 VAPD..ADLWA.....YKVLGDDGSgYADDIAA..AIRHAGDQATAL-------..--------.
  56 VAPQ..TSIYA.....VRVLDNQGS.GT-----..-------------------..--------.
  57 SVPI..TPLTD.....NHIIGSNDP.TS----P..QIEATLDIQYILG------..VLLVQLDG.
  58 VAYG..AKVIP.....VRVLGKCGG.YDSDITD..GMYWSAGGHIDGVPDN---..--------.
  59 --KN..VNIVG.....VRVLGCNGS.GS-----..-------------------..--------.
  60 --KK..VSIFG.....VKVLDDNGS.GS-----..-------------------..--------.
  61 VAHS..VEIYA.....VKALGNGGY.GS-----..----WSDLIIAIDLAVKGP..DGVIDADG.
  62 --KK..VSIFG.....VKVLDDNGS.GS-----..-------------------..--------.
  63 GLPA..ANFQK.....VDQNGGTNY.PKDDPDDasGDGWGVETALDLQIAHAVApaAKLILCTA.
  64 --KN..AKLFA.....VKVLDDQGS.GS-----..-------------------..--------.
  65 TAPK..ASILA.....VRVLDNSGS.GT-----..-------------------..--------.
  66 --KK..AKLYG.....VKVLDNQGS.GS-----..-------------------..--------.
  67 MAPN..TRILA.....VRALDRNGS.GT-----..-------------------..--------.
  68 TAPK..ASILA.....VRVLDNSGS.GT-----..-------------------..--------.
  69 MAPN..TRILA.....VRALDRNGS.GT-----..-------------------..--------.
  70 VSPS..ASLYA.....VKVLDSTGS.GQ-----..-------------------..--------.
  71 VAPE..ADLWA.....YKVLGDDGSgYADDIAE..AIRHAGDQATALN------..--------.
  72 VAYG..AKVIP.....VRVLGKCGG.YDSDITD..GMYWSAGGHIDGVPDN---..--------.
  73 VMPNqnANIHV.....INVFNEAGW.GY-----..-------------------..--------.
  74 --KK..TKIYG.....VKVLDNSGS.GS-----..-------------------..--------.
  75 LLPNqnVNLHI.....VKVFNESGW.GY-----..-------------------..--------.
  76 GIPR..TGHLNvi6gnVTTGGQSGE.NELDAEW..SGAFAPAANVTIVFSNGYV..------GG.
  77 TAYG..AKVVP.....VRVLGKCGG.SLSDIAD..AIVWASGGTVSGIPA----..--------.
  78 IAPE..AKILP.....VRVILEDGD.PS-----..-------------------..-------R.
  79 IAPR..ARVAV.....YKVTWPEGR.YT-----..-------------------..--------.
  80 --KK..TKILG.....IKVLSDQGS.GD-----..-------------------..--------.
  81 --KK..ANVYA.....VKVLRSNGS.GT-----..----MADVVKGVEFAATSH..VEQVLRAK.
  82 --KK..ANVYA.....VKVLRSNGS.GT-----..----MADVVKGVEFAATSH..VEQVLRAK.
  83 --KK..TSLFA.....VKVLDANGQ.GS-----..-------------------..--------.
  84 VAPD..ATLLA.....YRVLGPGGS.GT-----..-------------------..--------.
  85 --KK..ASILG.....VKVLEDSGS.GS-----..-------------------..--------.
  86 VAPM..VQIMP.....VRALGTDGS.GD-----..-------------------..--------.
  87 IAPR..AQLQG.....FNLLDDNSQ.QL-----..------------------Q..KDWLYALG.
  88 --KK..TNLLS.....VKVFQGESS.STSIILD..GFNWAVNDIVSKGRTKKA-..--------.
  89 VAPD..AQLLA.....MKVFSNNAK.NSGAYDD..DIISAIEDSVKLG------..--------.
  90 --KK..ANLLS.....VKVFQGESS.STSIILD..GFNWAANDIVSKGR-----..--------.
  91 --KK..TNLLS.....VKVFQGESS.STSIILD..GFNWAVNDIVSKGRTKKA-..--------.
  92 VAYK..AKVLP.....VRVLGHCGG.SFSDITD..AIVWASGGHVEGVPDN---..--------.
  93 --KK..TNLLS.....VKVFQGESS.STSIILD..GFNWAVNDIVSKGRTKKA-..--------.
  94 --KR..VTIFG.....VKVLPARGT.SP-----..-------------------..--------.
  95 VSPG..TNLLV.....YRVFGKSKS.KE-----..-------------------..--------.
  96 VAPG..ATLAV.....GKVLDDEGF.GS-----..-------------------..--------.
  97 VAPD..AKYLT.....AAMFQPGSV.GS-----..-------------------..--------.
  98 VAYN..AQIYV.....GNTNANDSF.LFGP---..-------------------..--------.
  99 --AN..TKLVA.....VKVFAGRSA.ALSVINQ..GFTWALNDYISKR------..--------.
 100 LAPG..VEILP.....IRMPEKIEG.-------..-------------------..------LD.
 101 --PG..AKVIS.....ALVLPNNEG.TF-----..-------------------..--------.
 102 VAYN..AQLYV.....GNTNANDSF.LFG----..-------------------..--------.
 103 VASG..VNLYM.....ARVLGDDGS.GS-----..-------------------..--------.
 104 VAYN..SKVSG.....IRILSGQIT.AE-----..-------------------..--------.
 105 VAWK..SQVSG.....IRILSGPIT.SS-DEAE..AMVYGLD------------..--------.
 106 ----..-----.....---------.-------..-------------------..--------.
 107 ----..-----.....---------.-------..-------------------..--------.
 108 AAPG..AKIVS.....AKACVYAGG.CT-----..-------------------..--------.
 109 VAYG..SKVAG.....LRMLDQPFM.TD-----..-------------------..--------.
 110 ----..-----.....---------.-------..-------------------..--------.
 111 VAFG..SKVAG.....LRMLDQPFM.TD-----..-------------------..--------.
 112 VAFG..SKVAG.....LRMLDQPFM.TD-----..-------------------..--------.
 113 VAFG..SKVAG.....LRMLDQPFM.TD-----..-------------------..--------.


             110       120            130            140            150
              |         |              |              |              |
   1 ....DQSASGNTGLTQAFNQAVSDN.....VAKVINVSLGW.....CEADANADG.....TLQAE
   2 ....DQSASGNTGLTQAFNQAVSDN.....VAKVINVSLGW.....CEADANADG.....TLQAE
   3 ....DQSASGNTGLTQAFNQAVSDN.....VAKVINVSLGW.....CEADANADG.....TLQAE
   4 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
   5 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
   6 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
   7 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
   8 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
   9 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  10 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  11 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  12 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  13 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  14 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  15 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  16 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  17 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  18 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  19 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  20 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  21 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  22 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  23 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PSGST----.....---AL
  24 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PSGST----.....---AL
  25 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  26 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  27 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  28 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  29 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PSGST----.....---AL
  30 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  31 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  32 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  33 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  34 ....-------YSWIINGIEWAIAN.....NMDVINMSLGG.....PSGSA----.....---AL
  35 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  36 ....-------YSGIVSGIEWATTN.....GMDVINMSLGG.....ASGST----.....---AM
  37 ....-------YSAIVSGIEWATQN.....GLDVINMSLGG.....PSGST----.....---AL
  38 ....-------YSGIVSGIEWATTN.....GMDVINMSLGG.....ASGST----.....---AM
  39 ....-------YSGIVSGIEWATTN.....GMDVINMSLGG.....ASGST----.....---AM
  40 ....-------YSGIVSGIEWATTN.....GMDVINMSLGG.....ASGST----.....---AM
  41 ....-------YSGIVSGIEWVTTN.....GMDVINMSLGG.....ASGST----.....---AM
  42 gds.SSSGITDAGITASYNRAVTDN.....IAKLINVSLGE.....DETAAQQSG.....TQAAD
  43 ....NESSLPH--------------.....---VHTVSYGD.....DEDSL-SSI.....YIQRV
  44 ....NESALPH--------------.....---VHTVSYGD.....DEDSL-SSA.....YIQRV
  45 ....-------YSGIVSGIEWATTN.....GMDVINMSLGG.....ASGST----.....---AM
  46 ....NESALPH--------------.....---VHTVSYGD.....DEDSL-SSA.....YIQRV
  47 ....NESSLPH--------------.....---VHTVSYGD.....DEDSL-SSI.....YIQRV
  48 ....NESALPH--------------.....---VHTVSYGD.....DEDSL-SSA.....YIQRV
  49 ....-------LDSIASGIRYAADQ.....GAKVLNLSLGC.....ECNST----.....---TL
  50 ....---------------------.....-KTIISMSLGS.....SANNS----.....---LI
  51 ....---------------------.....-KTIISMSLGS.....SANNS----.....---LI
  52 esntCQSMLQNQNIVNGINEFVSSN.....SKCQVAL----.....-EQDTQQNY.....HIYSS
  53 ....-------LDAVAQGIREAADS.....GAKVISLSLGA.....PNGGT----.....---AL
  54 ....--------------YEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  55 ....--------------------N.....TKVVINMSLGS.....SGESS----.....---LI
  56 ....-------LDAVAQGIREAADS.....GAKVISLSLGA.....PNGGT----.....---AL
  57 ....SGLKVIVYRLYGFHHLFATKD.....VPLVNSISYGW.....NEEDQCENGi15aqYVARV
  58 ....-------------------QN.....PAQVINMSLGG.....DGDCS----.....--QSS
  59 ....-------YSGVISGIDWVKNNas...GPSVANMSLGG.....--------G.....VSQAV
  60 ....-------LSNVIAGMDFVASDyr7cpRGVVASMSLGG.....--------G.....YSATV
  61 ....DGVVAGDPD----------DD.....APEVISMSLGG.....SSPPP----.....---EL
  62 ....-------LSNVIAGMDFVASDyr7cpRGVVASMSLGG.....--------G.....YSATV
  63 ....KSASDTNLN---ACIKTLTNL.....HVNHISMSYGG.....SEGDT----.....---SS
  64 ....-------YSGIISGMDFVAQDsk7cpNGHIASMSLGG.....--------G.....YSASV
  65 ....-------WTAVANGITYAADQ.....GAKVISLSLGG.....TVGNS----.....---GL
  66 ....-------YSGIISGMDYVAQDsk7cpNGAIASMSLGG.....--------G.....YSASV
  67 ....-------LSDIADAIIYAADS.....GAEVINLSLGC.....DCHTT----.....---TL
  68 ....-------WTAVANGITYAADQ.....GAKVISLSLGG.....TVGNS----.....---GL
  69 ....-------LSDIADAIIYAADS.....GAEVINLSLGC.....DCHTT----.....---TL
  70 ....-------YSWIINGIEWAISN.....NMDVINMSLGG.....PTGST----.....---AL
  71 ....---------------------.....TKVVINMSLGS.....SGESS----.....---LI
  72 ....-------------------QN.....PAQVVNMSLGG.....GG------G.....CSQNS
  73 ....------SSSLVAAIDTCVTSG.....GANVVTMSLGG.....SGSTT----.....---TE
  74 ....-------YSGIISGMDFAVQDsk7cpKGVVANMSLGG.....--------G.....KAQSV
  75 ....-------SSTLVRAIQTCADN.....GAKIVNMSLGG.....SQSSR----.....---TE
  76 ....PQLVGNLLNYYYEYYYMVNYL.....NPNVISISVTV.....PESFLAAYYpa...MLDMI
  77 ....------------------NAN.....PAEVINMSLGG.....GGSCS----.....--TTM
  78 ....AKARKTRGNALAEGIRWAADH.....GADIINLSLGD.....DSASA---H.....PEPGE
  79 ....--------SDVLAGIDQAIAD.....GVDVISISLGY.....DGVPLYEDP.....IAIAS
  80 ....-------YSGILAGMDFAIQDsr7cpKGVVANMSLGG.....--------G.....YSAAI
  81 ....DGKRKGFKGS-----------.....---VANMSLGG.....--------G.....KTQAL
  82 ....DGKRKGFKGS-----------.....---VANMSLGG.....--------G.....KTQAL
  83 ....-------NSGVIAGMDFVTKDas7cpKGVVVNMSLGG.....PSSSA----.....----V
  84 ....-------TENVIAGVERAVQD.....GADVMNLSLGNsl...NNPDW----.....---AT
  85 ....-------LSGVIAGMDFVATDrk7csKGTVASMSLGG.....--------G.....YSATV
  86 ....-------ISAVVQAIVWAVDH.....GANIINLSLGS.....NEASE----.....---AL
  87 ....DSNASRDNRVFNHSYRMSVVD.....PRSANSL----.....DQSQL----.....---DR
  88 ....---------------------.....---AINMSLGG.....--------G.....YSYAF
  89 ....---------------------.....-ADVINMSLGS.....VSSDV---G.....PSDPQ
  90 ....--------------------T.....GKSAINMSLGG.....--------G.....YSYAF
  91 ....---------------------.....---AINMSLGG.....--------G.....YSYAF
  92 ....---------------------re...PAEIINISLGG.....FGPCD----.....--SAM
  93 ....---------------------.....---AINMSLGG.....--------G.....YSYAF
  94 ....NSVIIKGMDFVHAMPSGVNAP.....TDVVVNMSLGG.....--------G.....YSKAT
  95 ....--------CWILKAIIDATNN.....GANVINLSLGQyiki.PNGDIWESA.....EALRY
  96 ....-------ESEIIAGMEWAARDv....DADIVSMSLGS.....TEPSDGTDP.....MAEAV
  97 ....--------AGVAKAILWMVDN.....GAKVLNNSWGG.....AGFDP----.....---LI
  98 ....----TPDPQYFKAVYSALVDS.....GVRAINNSWGSq12gdLHAAYAQHY.....NQNTW
  99 ....---------------------dtl..PRGVLNFSGGG.....--------P.....KSASQ
 100 ....FTSGHNAARDFSKAIRFAADS.....DAKVINISMGQ.....AESGTKGGV.....DTSEL
 101 ....AQVIAGMQYVLDPDNNADTDD.....GADVVNMSLGI.....PGTWN----.....---EF
 102 ....---PTPDPKYFKAVYTALVDS.....GVRAINNSWGSq12agLHAAYAQHY.....NQGTW
 103 ....-------SSGIINGVNWCAAQlk8teSKVVISLSLGG.....GRASQ----.....---TE
 104 ....DEAASLIYGL----------D.....VNDIYSCSWGP.....SDDGKTMQApdtlvKKAII
 105 ....---------------------.....TNDIYSCSWGPt....DNGKVLSEPdviv.KKAMI
 106 ....---------------------.....-----------.....----YLGSG.....YLRRS
 107 ....------------SSINWAVGNkgs..AAAVANMSLGG.....--------G.....ASQAV
 108 ....------SVALTEGMIELVGNQ.....RVDIVNMSIGG.....--LPALNDG.....NNTRS
 109 ....---------LIEANAMGHMPN.....VIDIYSASWGP.....TDDGKTVDGprnltMRAIV
 110 ....---------------------.....-----------.....---------.....-----
 111 ....---------LIEANAMGHMPN.....VIDIYSASWGP.....TDDGKTVDGprnltMRAIV
 112 ....---------LIEANAMGHMPN.....VIDIYSASWGP.....TDDGKTVDGprnltMRAIV
 113 ....---------LIERNAMGHMPN.....VIDIYSASWGP.....TDDGKTVDGprnltMRAIV


             160       170       180                  190       200    
              |         |         |                    |         |    
   1 DRIFATAAAQGQTFSVSSGDEGVYECNNRGY.....PD.GST.....YSVSWPASSPNVIAVGGT
   2 DRIFATAAAQGQTFSVSSGDEGVYECNNRGY.....PD.GST.....YSVSWPASSPNVIAVGGT
   3 DRIFATAAAQGQTFSVSSGDEGVYECNNRGY.....PD.GST.....YSVSWPASSPNVIAVGGT
   4 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPAKYPSVIAVGAV
   5 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
   6 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
   7 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
   8 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
   9 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  10 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  11 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  12 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPAKYPSVIAVGAV
  13 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPAKYPSVIAVGAV
  14 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPAKYPSVIAVGAV
  15 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPAKYPSVIAVGAV
  16 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  17 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPAKYPSVIAVGAV
  18 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  19 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  20 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  21 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GGS.....STVGYPGKYPSVIAVGAV
  22 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  23 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GSS.....STVGYPAKYPSTIAVGAV
  24 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GSS.....STVGYPAKYPSTIAVGAV
  25 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  26 KAAVDKAVASGVVVVAAAGNEGST-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  27 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  28 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  29 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GSS.....STVGYPAKYPSTIAVGAV
  30 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  31 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  32 KAAVDKAVASGVVVVAAAGNEGTS-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  33 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  34 KAAVDKAVASGVVVVAAAGNEGST-------.....--.GSS.....STVGYPGKYPSVIAVGAV
  35 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  36 KQAVDNAYARGVVVVAAAGNSGNS-------.....--.GST.....NTIGYPAKYDSVIAVGAV
  37 KQAVDKAYASGIVVVAAAGNSGNS-------.....--.GSQ.....NTIGYPAKYDSVIAVGAV
  38 KQAVDNAYARGVVVVAAAGNSGNS-------.....--.GST.....NTIGYPAKYDSVIAVGAV
  39 KQAVDNAYARGVVVVAAAGNSGNS-------.....--.GST.....NTIGYPAKYDSVIAVGAV
  40 KQAVDNAYARGVVVVAAAGNSGSS-------.....--.GNT.....NTIGYPAKYDSVIAVGAV
  41 KQAVDNAYARGVVVVAAAGNSGSS-------.....--.GNT.....NTIGYPAKCDSVIPVGGE
  42 DAIFQQAVAQGQTFSIASGDAGVYQWSTDPTs15vkID.LTH.....YSVSEPASSPYVIQVGGT
  43 NTEFMKAAARGLTLLFASGDTGAGCWSVSGR.....H-.--K.....FRPSFPASSPYVTTVGGT
  44 NTELMKAAARGLTLLFASGDSGAGCWSVSGR.....H-.--Q.....FRPTFPASSPYVTTVGGT
  45 KQAVDNAYARGVVVVAAAGNSGSS-------.....--.GST.....NTIGYPAKYDSVIAVGAV
  46 NTELMKAAARGLTLLFASGDSGAGCWSVSGR.....H-.--Q.....FRPTFPASSPYVTTVGGT
  47 NTEFMKAAARGLTLLFASGDTGAGCWSVSGR.....H-.--K.....FRPSFPASSPYVTTVGGT
  48 NTEFMKAAARGLTLLFASGDSGAGCWSVSRR.....H-.--Q.....FRPSFPASSPYVTTVGGT
  49 KSAVDYAWNKGAVVVAAAGNDNVS-------.....--.---.....-RTFQPASYPNAIAVGAI
  50 SSAVNYAYSKGVLIVAAAGNSGYS-------.....--.--Q.....GTIGYPGALPNAIAVAAL
  51 SSAVNYAYSKGVLIVAAAGNSGYA-------.....--.--Q.....GTIGYPGALPNAIAVAAL
  52 CTCDK-------LKPYSDSDAGFKIVGYSYD.....QDaGTL.....FQPDYPASSPFITSVGAT
  53 QQAVQYAWNKGSVIVAAAGNAGNT-------.....--.---.....-KANYPAYYSEVIAVAST
  54 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  55 TNAVNYSYNKGVLIIAAAGNSGPY-------.....--.--Q.....GSIGYPGALVNAVAVAAL
  56 QQAVQYAWNKGSVIVAAAGNAGNT-------.....--.---.....-KANYPAYYSEVIAVAST
  57 NTEFQKIGLRGITLFAASGDSGAN-GRTDPD.....CS.ESN.....LNPAYPAASPYITSVGAT
  58 QRIIDKTTNLGALIVIAAGNENQD-------.....--.---.....ASRTWPSSCNNVLSVGAT
  59 DDAVNNAVASGVSFVVAAGNDNSNACNYS--.....--.---.....-----PARAANAITVGST
  60 NQAAARLQSSGVFVAVAAGNDNRDAANTS--.....--.---.....-----PASEPSVCTVGAT
  61 HDVIKAAYNLGITIVAAAGNDGAD-------.....--.---.....-SPSYPAAYPEVIAVGAI
  62 NQAAARLQSSGVFVAVAAGNDNRDAANTS--.....--.---.....-----PASEPSVCTVGAT
  63 DSYFQQAQEAGISLFASAGDSGAE-------.....--.---.....--AEYPAASQYVVAVGGT
  64 NQGAAALVRSGVFLAVAAGNDNRDAQNTS--.....--.---.....-----PASEPTACTVGAT
  65 QQAVNYAWNKGSVVVAAAGNAGNT-------.....--.---.....-APNYPAYYSNAIAVAST
  66 NQGAAALVNSGVFLAVAAGNDNRDAQNTS--.....--.---.....-----PASEPSACTVGAS
  67 ENAVNYAWNKGSVVVAAAGNNGSS-------.....--.---.....-TTFEPASYENVIAVGAV
  68 QQAVNYAWNKGSVVVAAAGNAGNT-------.....--.---.....-APNYPAYYSNAIAVAST
  69 ENAVNYAWNKGSVVVAAAGNNGSS-------.....--.---.....-TTFEPASYENVIAVGAV
  70 KTVVDKAVSSGIVVAAAAGNEGSS-------.....--.GST.....STVGYPAKYPSTIAVGAV
  71 TNAVDYAYDKGVLIIAAAGNSGPK-------.....--.--P.....GSIGYPGALVNAVAVAAL
  72 QRMIDKTTNLGALIVIAAGNENQD-------.....--.---.....ASRTWPSSCNNVLSVGAT
  73 RNALNTHYNGGVLLIAAAGNAGDS-------.....--.---.....-TYTYPPSYDIVMSVAAV
  74 NDGAAAMIRAGVFLAVAAGNDNANAANYS--.....--.---.....-----PASEPTVCTVGAT
  75 QNAMDALYERGVLMIAAAGNSGNT-------.....--.---.....-AHSYPASYDSVMSVAAV
  76 HNIMLQAAAQGISVLAASGDWGYESDHPPPN.....FHiGTY.....NTIWYPESDPYVTSVGGI
  77 QNAINGAVSRGTTVVVAAGNDASN-------.....--.---.....VSGSLPANCANVIAVAAT
  78 DEAIQYALKKGVVVVASAGNGGEL-------.....--.--G.....DHISYPAAYPGVIAATAV
  79 FAAM----EKGVVVSTSAGNAGPFFGNMH--.....--.---.....------NGIPWVLTVAAG
  80 NQAAAKMIQSNVFLAVAAGNDAKDASQTS--.....--.---.....-----PASEPSVCTVGAT
  81 DAAVNAAVKAGIHFAVAAGNDNADACNYS--.....--.---.....-----PAAAELPVTVGAS
  82 DAAVNAAVKAGIHFAVAAGNDNADACNYS--.....--.---.....-----PAAAELPVTVGAS
  83 NRAAAEITSAGLFLAVAAGNEATDASSSS--.....--.---.....-----PASEESACTVGAT
  84 STALDWAMSEGVVAVTSNGNSGPN-------.....--.--G.....WTVGSPGTSREAISVGAT
  85 NQAAARLQASGVFVAVAAGNDNRDAAQTS--.....--.---.....-----PASEPSVCTVGAT
  86 QSAVRYADEKGVAVVAAAGNAGNN-------.....--.ELT.....YPAAYARTSAGLLSVGSV
  87 LFEQQTLKAQGAAYIKAAGN-GFNKIAAGGYv10pkLP.FEN.....SNLDPSNSNFWNLVVSAL
  88 NNAVENAFDEGVLSVVAAGNENSDASNTS--.....--.---.....-----PASAPNALTVAAI
  89 QQAVAKASEAGVINVISAGNSGVAGSTADGN.....PV.NNTgtselSTVGTPGVTPDALTVASA
  90 NQAVEDAYDEGVLSVVAAGNDNIDASDSS--.....--.---.....-----PASAPNALTVAAS
  91 NNAVENAFDEGVLSVVAAGNENSDASNTS--.....--.---.....-----PASAPNALTVAAI
  92 QAAINGAVSRGTTVVVAAGNGGSD-------.....--.---.....VSSAVPANCANVVSVAAT
  93 NNAVENAFDEGVLSVVAAGNENSDASNTS--.....--.---.....-----PASAPNALTVAAI
  94 NQAAARLVRAKYFVAVASGNNNRDARNYS--.....--.---.....-----PASEPSVCTVGGT
  95 KFAIDYATRHNVIVVAATGNDGLSDDNGEVKt11qdMS.QND.....TVEDYPSVLPNAIAVGSS
  96 NTLSR---ETGALFVIAAGNTGAP-------.....--.---.....SSIGSPGAADAALTVGAV
  97 KAAMDYALERNVTVVVSAGNESRE-------.....--.---.....-YYQRPALFAGVIPSAAL
  98 LDAAADVAKAGVINVFSAGNSGYANASVR--.....--.-SA.....LPYFQPGLEGHWLAVSGL
  99 DALWSRATQEGLLVAIAAGNDAVDACNDS--.....--.---.....-PGNIGGSTSGIITVGSI
 100 DAAVKYAVDKGKLIFAAAGNEGDG-------.....--.--A.....NRPRFPASTPGVVAVGSI
 101 IVPVNNMLKAGVVPVFAIGNFGPA-------.....--.--A.....GSTGSPGNLPQAIGVGAV
 102 LDAAADVAKAGVINVFSAGNSGYANASVR--.....--.-SA.....LPYFQPELEGHWLAVSGL
 103 QRAYTSVYNKGVLTVAATGNDGAA-------.....--.---.....--VSYPAAYTNVVGVGAI
 104 KGVTEGRDAKGALYVFASGNGGMF-------.....--.GDS.....CNFDGYTNSIFSITVGAI
 105 KGIQEGRDKKGAIYVFASGNGGRF-------.....--.GDS.....CNFDGYTNSIYSITVGAI
 106 DVEFQKLALMGITIIIADGDNGAGDLGAPPMlt...PD.CSTr....LNPDWP--SQRLTSRLGL
 107 DDAVNNAASKNLVMAVAAGNENQNACNVS--.....--.---.....-----PARAVNAITVGAT
 108 ALYNRIIDEYGVQIFISAANSGAG-------.....--.--T.....NTIADPSVATDAVSVAAG
 109 NGVNNGRNGLGNVYVWASGDGGPN-------.....--.-DD.....CNCDGYAASMWTISINSA
 110 -------------------------------.....--.---.....------GNGYTAITRGLT
 111 NGVNNGRNGLGNVYVWASGDGGPN-------.....--.-DD.....CNCDGYAASMWTVSINSA
 112 NGVNNGRNGLGNVYVWASGDGGPN-------.....--.-DD.....CNCDGYAASMWTVSINSA
 113 NGVNNGRNGLGNVYVWASGDGGPN-------.....--.-DD.....CNCDGYAASMWTVSINSA


         210                  220            230       240       250   
          |                    |              |         |         |   
   1 TLYTTSA.GAY.....SNE.....TVWNEGL.....DSNGKLWATGGGYSVYESKPSWQSVVSGT
   2 TLYTTSA.GAY.....SNE.....TVWNEGL.....DSNGKLWATGGGYSVYESKPSWQSVVSGT
   3 TLYTTSA.GAY.....SNE.....TVWNEGL.....DSNGKLWATGGGYSVYESKPSWQSVVSGT
   4 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
   5 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
   6 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
   7 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
   8 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
   9 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  10 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  11 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  12 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  13 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  14 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  15 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  16 NSANQRA.SFS.....SAG.....-------.....-----------------------------
  17 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  18 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  19 NSANQRA.SFS.....SAG.....-------.....-----------------------------
  20 NSSNQRA.SFS.....SAG.....-------.....-----------------------------
  21 NSSNQRA.SFS.....SVG.....-------.....-----------------------------
  22 NSSNQRA.SFS.....SVG.....-------.....-----------------------------
  23 NSSNQRA.SFS.....SAG.....-------.....-----------------------------
  24 NSSNQRA.SFS.....SAG.....-------.....-----------------------------
  25 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  26 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  27 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  28 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  29 NSSNQRA.SFS.....SAG.....-------.....-----------------------------
  30 NSSNQRA.SFS.....SAG.....-------.....-----------------------------
  31 NSSNQRA.SFS.....SAG.....-------.....-----------------------------
  32 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  33 NSSNQRA.SFS.....SAG.....-------.....-----------------------------
  34 DSSNQRA.SFS.....SVG.....-------.....-----------------------------
  35 NSANQRA.SFS.....SAG.....-------.....-----------------------------
  36 DSNSNRA.SFS.....SVG.....-------.....-----------------------------
  37 DSNKNRA.SFS.....SVG.....-------.....-----------------------------
  38 DSNSNRA.SFS.....SVG.....-------.....-----------------------------
  39 DSNSNRA.SFS.....SVG.....-------.....-----------------------------
  40 DSNSNRA.SFS.....SVG.....-------.....-----------------------------
  41 DSNSNRS.SFS.....SVG.....-------.....-----------------------------
  42 TLSTS-G.TTW.....SGE.....TVWNEGLsa8qgDNNQRLWATGGGVSLYEAAPSWQSSVSSS
  43 SFKNPF-.---.....---.....-----LI.....TDEVVDYISGGGFSNVFPRPPYQEEAVAQ
  44 SFQEPF-.---.....---.....-----LI.....TNEIVDYISGGGFSNVFPRPSYQEEAVTK
  45 DSNSNRA.SFS.....SVG.....-------.....-----------------------------
  46 SFQEPF-.---.....---.....-----LI.....TNEIVDYISGGGFSNVFPRPSYQEEAVTK
  47 SFKNPF-.---.....---.....-----LI.....TDEVVDYISGGGFSNVFPRPPYQEEAVAQ
  48 SFQNPFR.---.....---.....------V.....TTEIVDYISGGGFSNVFPQPSYQEEAVVQ
  49 DSNDRKA.SFS.....NYG.....-------.....-----------------------------
  50 ENVQQNG.TYR.....VAD.....-------.....YSSRGYISTAGDYVIQE------------
  51 ENVQQNG.TYR.....VAD.....-------.....YSSRGYISTAGDYVIQE------------
  52 QITDVTK.PEI.....VCS.....-------.....VATGAIITGGGGVAITQAQPSYQADAVAT
  53 DQSDRKS.SFS.....TYG.....-------.....-----------------------------
  54 BSANQRA.SFS.....SAG.....-------.....-----------------------------
  55 ENKVENG.TYR.....VAD.....-------.....FSSRGYSWTDGDYAIQK------------
  56 DQSDRKS.SFS.....TYG.....-------.....-----------------------------
  57 QISQSSG.VAK.....LPNp27ilHQVEDFL.....WLPQHCLSEGSHCSILQVRCNLASKLLLQ
  58 TPKGKRA.PFS.....NYG.....-------.....-----------------------------
  59 TSSDARS.SFS.....NYG.....-------.....-----------------------------
  60 DSSDRRS.SFS.....NYG.....-------.....-----------------------------
  61 DENGNVP.SWS.....NRN.....-------.....-----------------------------
  62 DSSDRRS.SFS.....NYG.....-------.....-----------------------------
  63 TLHTNSD.GSF.....NSE.....-------.....---TAWSGSGGGCSKYTKVIPEQNADPGY
  64 ASDDSRS.TFS.....NYG.....-------.....-----------------------------
  65 DQNDNKS.SFS.....TYG.....-------.....-----------------------------
  66 AENDSRS.SFS.....NYG.....-------.....-----------------------------
  67 DQYDRLA.SFS.....NYG.....-------.....-----------------------------
  68 DQNDNKS.SFS.....TYG.....-------.....-----------------------------
  69 DQYDRLA.SFS.....NYG.....-------.....-----------------------------
  70 NSSNQRA.SFS.....SAG.....-------.....-----------------------------
  71 ENTIQNG.TYR.....VAD.....-------.....FSSRGHKRTAGDYVIQK------------
  72 TPKGKRA.PFS.....NYG.....-------.....-----------------------------
  73 DSNLDHA.AFS.....QYTd108aGAKGIIV.....YSNTALPRLQNPFVVDAD--SEILIPSMS
  74 TSSDARS.SFS.....NYG.....-------.....-----------------------------
  75 DSNYDHA.SFS.....QATn109aGALAAMV.....YSNQQ--RPGLQNPFVLDQFNTYPLLSVS
  76 FLNASSN.GSI.....VEI.....-------.....--SGWDYSTGGNSVVYPAQIYEITSLIPF
  77 TSAGAKA.SYS.....NFG.....-------.....-----------------------------
  78 DRYGTRA.AFS.....TRR.....-------.....-----------------------------
  79 NIDRSFA.GTL.....TLGn64snVAGAILI.....SNHTKLFELGGGVSCPCLVISPKDAAALI
  80 DSSDRLS.SFS.....NYG.....-------.....-----------------------------
  81 AFDDSRA.YFS.....NYG.....-------.....-----------------------------
  82 AFDDSRA.YFS.....NYG.....-------.....-----------------------------
  83 DKTDTLA.EYS.....NFG.....-------.....-----------------------------
  84 QLPLNE-.YAV.....TFGs117kLTVSKAL.....GEQVADFSSRGPVMDTWM-----------
  85 DSSDRRS.TFS.....NFG.....-------.....-----------------------------
  86 SDSDVKS.GFS.....NYA.....-------.....-----------------------------
  87 NADGVRS.SYS.....SVG.....-------.....-SNIFLSATGGEYGTDTP-----------
  88 NKSNARA.SFS.....NYG.....-------.....-----------------------------
  89 ENSKVTT.DTV.....KDEl116wLKQQKKV.....RASRLKFGTALIDNSRAGKMSDFTSWGPT
  90 TKSNTRA.SFS.....NYG.....-------.....-----------------------------
  91 NKSNARA.SFS.....NYG.....-------.....-----------------------------
  92 RLTGGLA.YYS.....NFG.....-------.....-SLIDLAAPGGGARDLETDTLYDGPIG--
  93 NKSNARA.SFS.....NYG.....-------.....-----------------------------
  94 DKFDSV-.YMS.....NWG.....-------.....---PAVDINGPGVDVLSTLPNRRTVCFF-
  95 DNNNQRS.SFS.....NYY.....-----NQ.....YQDNFILAPGGGTPLLDQ--YGQEEWYNQ
  96 DSADQAA.WFT.....SAG.....-------.....--------------------------PRY
  97 AVNNTKA.SFS.....SFG.....-------.....---RHISVAAPGTDILMASPLFINDDGTR
  98 DKANNQK.---.....---.....-------.....--------------------------YNQ
  99 DSSDKIS.VWSggqgsNYG.....-------.....-----------------------------
 100 NEKVKRS.SFS.....EWG.....-------.....-----------------------------
 101 DSNGQVA.SFS.....SRG.....-------.....------------------PVAWQGEISGV
 102 DKTNNQK.---.....---.....-------.....--------------------------YNK
 103 DSAEARA.SFS.....NFG.....-------.....---SQVDLVGPGVSVLSSIPLGQGTRASA
 104 DWKGLHP.PYS.....ESC.....-------.....---------------------------SA
 105 DYKGLHP.QYS.....EAC.....-------.....---------------------------SA
 106 YIHHTLA.EPI.....CYT.....DIDCRLDnp9vsLDNGLFWTTGGGFADYPPRPQYQEAIISQ
 107 TKTDSRDtGYS.....NYG.....-------.....-----------------------------
 108 ASKETW-.-LA.....NYG.....AKAKEEYwaqn.YSSRGPREDGGFKPNIMAPGSAISAVPMF
 109 RNDGQTA.GYD.....ESC.....-------.....-SSTLASTFSNGKSN--------------
 110 TNTDARW.SFS.....NYG.....-------.....-----------------------------
 111 TNDGQTA.GYD.....ESC.....-------.....---------------------------SS
 112 TNDGQTA.GYD.....ESC.....-------.....---------------------------SS
 113 TNDGQTA.GYD.....ESC.....-------.....---------------------------SS


                    260            270                 280           29
                     |              |                   |             
   1 .....PG.....RRLLPDISFDAAQG.....TGALIY.....NYGQ.....LQQIG....GTSLA
   2 .....PG.....RRLLPDISFDAAQG.....TGALIY.....NYGQ.....LQQIG....GTSLA
   3 .....PG.....RRLLPDISFDAAQG.....TGALIY.....NYGQ.....LQQIG....GTSLA
   4 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYS....GTXMA
   5 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTSMA
   6 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAKS....GTCMA
   7 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTSMA
   8 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYS....GTCMA
   9 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTXMA
  10 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTSMA
  11 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTSMA
  12 .....--.....----PELDVMAPGV.....SICSTL.....PGNK.....YGAYS....GTSMA
  13 .....--.....----PELDVMAPGV.....SICSTL.....PGNK.....YGAYS....GTSMA
  14 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAKS....GTSMA
  15 .....--.....----PELDVMAPGV.....SICSTL.....PGNK.....YGAKS....GTSMA
  16 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  17 .....--.....----PELDVMAPGV.....SICSTL.....PGNK.....YGAKS....GTSMA
  18 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTSMA
  19 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  20 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTCMA
  21 .....--.....----SELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTSMA
  22 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  23 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  24 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  25 .....--.....----PELDVMAPGV.....SICSTL.....PGNK.....YGAKS....GTSMA
  26 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTSMA
  27 .....--.....----PELDVMAPGV.....SIVSTL.....PGNK.....YGAKS....GTAMA
  28 .....--.....----PELDVMAPGV.....SICSTL.....PGNK.....YGAKS....GTSMA
  29 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  30 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  31 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  32 .....--.....----PELDVMAPGV.....SIVSTL.....PGNK.....YGAKS....GTAMA
  33 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  34 .....--.....----PELDVMAPGV.....SIQSTL.....PGNK.....YGAYN....GTSMA
  35 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAYN....GTSMA
  36 .....--.....----AELEVMAPGA.....GVYSTY.....PTNT.....YATLN....GTSMA
  37 .....--.....----SELEVMAPGV.....SVYSTY.....PSNT.....YTSLN....GTSMA
  38 .....--.....----AELEVMAPGA.....GVYSTY.....PTNT.....YATLN....GTSMA
  39 .....--.....----AELEVMAPGA.....GVYSTY.....PTNT.....YATLN....GTXMA
  40 .....--.....----AELEVMAPGA.....GVYSTY.....PTNT.....YATLN....GTSMA
  41 .....--.....----AELEVMAPVS.....GVYSTY.....PTNT.....YTTLN....GTSMA
  42 .....T-.....KRVGPDLAFDAASS.....SGALIV.....VNGS.....TEQVG....GTSLA
  43 .....FLk15asGRAYPDVAALSDGY.....WVVSNM.....V--P.....IPWVS....GTSAS
  44 .....FLs15asGRAYPDVAALSDGY.....WVVSNR.....V--P.....IPWVS....GTSAS
  45 .....--.....----AELEVMAPGA.....GVYSTY.....PTNT.....YATLN....GTSMA
  46 .....FLs15asGRAYPDVAALSDGY.....WVVSNR.....V--P.....IPWVS....GTSAS
  47 .....FLk15asGRAYPDVAALSDGY.....WVVSNM.....V--P.....IPWVS....GTSAS
  48 .....FLs15asGRAYPDVAALSDGY.....WVVSNS.....V--P.....IPWVS....GTSAS
  49 .....--.....----TWVDVTAPGV.....NIASTV.....PNNG.....YSYMS....GTSMA
  50 .....--.....----GDIEISAPGS.....SVYSTW.....YNGG.....YNTIS....GTSMA
  51 .....--.....----GDIEISAPGS.....SVYSTW.....YNGG.....YNTIS....GTSMA
  52 .....YIks...GTLPPSYSYMPPID.....SIQILLl17ntCPCA.....LESVD....GTSCS
  53 .....--.....----SWVDVAAPGS.....NIYSTY.....KGST.....YQSLS....GTSMA
  54 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YGAY-....--SMA
  55 .....--.....----GDVEISAPGA.....AIYSTW.....FDGG.....YATIS....GTSMA
  56 .....--.....----SWVDVAAPGS.....NIYSTY.....KGST.....YQSLS....GTSMA
  57 .....CC.....CKRISDVS---ALG.....SAILIE.....TGGN.....IQTVG....GTSAS
  58 .....--.....----ARVHLAAPGT.....NILSTI.....DVGQag7ssYGMKA....GTSMA
  59 .....--.....----NCLDIYAPGS.....SITSAW.....YNSDts...TNTIS....GTSMA
  60 .....--.....----RALDIFAPGT.....DITSTW.....IGGR.....TNTIS....GTSMA
  61 .....--.....----PEVA--APGV.....NILSTY.....PDDT.....YEELS....GTSMA
  62 .....--.....----RALDIFAPGT.....DITSTW.....IGGR.....TNTIS....GTSMA
  63 aslgcKG.....KKALPDLAALADPN.....SGITII.....FHGQe....LEGIG....GTSLA
  64 .....--.....----RIVDIFAPGT.....GILSTW.....INGR.....TNTIS....GTSMA
  65 .....--.....----SWVDVAAPGS.....SIYSTY.....PTST.....YASLS....GTSMA
  66 .....--.....----RVVDIFAPGS.....NVLSTW.....IVGR.....TNSIS....GTSMA
  67 .....--.....----TWVDVVAPGV.....DIVSTI.....TGNR.....YAYMS....GTSMA
  68 .....--.....----SVVDVAAPGS.....WIYSTY.....PTST.....YASLS....GTSMA
  69 .....--.....----TWVDVVAPGV.....DIVSTI.....TGNR.....YAYMS....GTSMA
  70 .....--.....----SELDVMAPGV.....SIQSTL.....PGGT.....YG---....-----
  71 .....--.....----GDVEISAPGA.....AVYSTW.....FDGG.....YATIS....GTSMA
  72 .....--.....----ARVHLAAPGT.....NILSTI.....DVGQag7ssYGMKA....GTSMA
  73 .....VD.....RTTGLALKAKLGQS.....TTVSNQ.....GNRD.....YEYYN....GTSMA
  74 .....--.....----NLVDIFAPGS.....NILSTW.....IGGT.....TNTIS....GTSMA
  75 .....VN.....RNVGQELAALVGQD.....ITVSTR.....TGED.....YQYYN....GTSMA
  76 tp...VI.....VRTYPDIAFVSAGGyn7fgFGLPLV.....FQGQ.....LFVWY....GTSGA
  77 .....--.....----TGIDVSAPGS.....SILSTL.....NSGTtt7asYASYN....GTSMA
  78 .....--.....--WYATVS--APGV.....DVIIAD.....PDHR.....YYEGW....GTSAA
  79 .....KYa39ypGILKPDVM--APGS.....LVLASW.....IPNEa14shYNMVS....GTSMA
  80 .....--.....----AAVDILAPGS.....DILSTW.....IGGI.....TKSIS....GTSMA
  81 .....--.....----KCTDIFAPGL.....NILSTW.....IGSPta...VNTIS....GTSMA
  82 .....--.....----KCTDIFAPGL.....NILSTW.....IGSPta...VNTIS....GTSMA
  83 .....--.....----SVVDLLAPGT.....DIKSTW.....NDGR.....TKIIS....GTSMA
  84 .....--.....--IKPDIS--APGV.....NIVSTI.....PTHDpd6ygYGSKQ....GTSMA
  85 .....--.....----KAVDIFAPGT.....GILSTW.....NNGG.....TNTIS....GTSMA
  86 .....--.....----ASLEVLAPGE.....RIATYA.....PNNK.....LALWT....GTSMS
  87 .....--.....----AMVTTDLPGC.....DMGYNR.....TDDPs17dyNGVMN....GTSSA
  88 .....--.....----SVVDIFAPGQ.....DILSAW.....IGSTta...TNTIS....GTSMA
  89 .....PE.....LDFKPEIT--APGG.....KIYSLA.....NDNK.....YQQMS....GTSMA
  90 .....--.....----SVVDIFAPGQ.....DILSAW.....IGSTta...TNTIS....GTSMA
  91 .....--.....----SVVDIFAPGQ.....DILSAW.....IGSTta...TNTIS....GTSMA
  92 .....--.....----SWIW--QTGY.....TGATTP.....TSGQ.....FTYIGpgfaGTSMA
  93 .....--.....----SVVDIFAPGQ.....DILSAW.....IGSTta...TNTIS....GTSMA
  94 .....--.....----FLIKIPAWRA.....EELTCM.....MQGR.....LT---....GTSMA
  95 .....KL.....----------FMKE.....QVLSTS.....NNGN.....YDYAD....GTSIS
  96 .....GD.....NALKPDLS--APGV.....GILAARsrlaeGSGD.....YTSMD....GTSMA
  97 .....KL.....GATPPDGS------.....------.....---G.....YVLMS....GTSFS
  98 .....CG.....IAKYWCIS--TPGA.....LINSTI.....PEGG.....YGVKS....GTSMS
  99 .....--.....----TCVDVFAPGS.....DIISAS.....YQSDsg...TLVYS....GTSMA
 100 .....--.....----PEIDVTAPGE.....DLVHAC.....IGGTg....VCRTS....GTSDA
 101 .....F-.....--TKPDIA--APGV.....NITSTV.....RNGG.....YQAMS....GSSQA
 102 .....CG.....IAKYWCIS--TPGA.....LINSTV.....PGGG.....YGVKS....GTSMS
 103 s....GG.....GVTFTDVS--AADK.....SGKATFs103vTGAD.....YDFFD....GTSMA
 104 .....VM.....VVTYSSGS----GN.....YIKTTD.....LDEKc....SNTHG....GTSAA
 105 .....VM.....VVTYSSGS----GE.....HIHTTD.....IKKKc....SATHG....GTSAA
 106 .....YLq15sgGRAYPDIS---TVG.....HNLMTV.....ISGS.....MTPVD....GTSPS
 107 .....--.....----SCLDIFAPGT.....NITSTW.....IGSTsa...TNTIS....GTSMA
 108 .....MD.....PEDIPQVSYKLPV-.....------.....---G.....LSMFN....GTSMA
 109 .....--.....----------SRDA.....GVATTD.....LYNNc....TASHS....GTSAA
 110 .....--.....----SCLDIFAPGS.....SITSAW.....YTSSta...TNTIS....GTSMA
 111 .....TL.....ASTFSNGKSSSRDA.....GVATTD.....LYNNc....TASHS....GTSAA
 112 .....TL.....ASTFSNGKSSSRDA.....GVATTD.....LYNNc....TASHS....GTSAA
 113 .....TL.....ASTFSNGKSSSRDA.....GVATTD.....LYNNc....TASHS....GTSAA


      0       300            310       320               330           
     |         |              |         |                 |           
   1 SPIFVGLWARLQSANS.....NSLGFPAASFYSAIS...STPS.....LVHDVKSGNNG.....Y
   2 SPIFVGLWARLQSANS.....NSLGFPAASFYSAIS...STPS.....LVHDVKSGNNG.....Y
   3 SPIFVGLWARLQSANS.....NSLGFPAASFYSAIS...STPS.....LVHDVKSGNNG.....Y
   4 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
   5 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
   6 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
   7 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
   8 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
   9 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  10 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  11 SPHVAGAAALILSKHP.....---NWTNTQVRSSLQ...NTT-.....-----------.....-
  12 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  13 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  14 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  15 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  16 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  17 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  18 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  19 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  20 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  21 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  22 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  23 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  24 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  25 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  26 SPHVAGAAALILSKHP.....---NWTNTQVRSSLQ...NTT-.....-----------.....-
  27 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  28 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  29 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  30 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  31 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  32 SPHVAGAAALILSKHP.....---NWTNTQVRSSLE...NTT-.....-----------.....-
  33 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  34 SPHVAGAAALILSKHP.....---NWTNTQVRSSLQ...NTT-.....-----------.....-
  35 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  36 SPHVAGAAALILSKHP.....---NLSASQVRNRLS...STA-.....-----------.....-
  37 SPHVAGAAALILSKYP.....---TLSASQVRNRLS...STA-.....-----------.....-
  38 SPHVAGAAALILSKHP.....---NLSASQVRNRLS...STA-.....-----------.....-
  39 SPHVAGAAALILSKHP.....---NLSASQVRNRLS...STA-.....-----------.....-
  40 SPHVAGAAALILSKHP.....---NLSASQVRNRLS...STA-.....-----------.....-
  41 SPHVAGTSALILSKHP.....---NLSASQVRNRLS...RTA-.....-----------.....-
  42 SPLFVGAFARIESAAN.....NAIGFPASKFYQAFP...TQTS.....LLHDVTSGNNG.....Y
  43 TPVFGGILSLINEHRIlngr.PPLGFLNPRLYQQHG...TGL-.....--FDVTHGCHEsc6eeV
  44 TPVFGGILSLINEHRIlsgr.PPLGFLNPRLYQQHG...AGL-.....--FDVTRGCHEsc6eeV
  45 SPHVAGAAALILSKHP.....---NLSASQVRNRLS...STA-.....-----------.....-
  46 TPVFGGILSLINEHRIlsgr.PPLGFLNPRLYQQHG...AGL-.....--FDVTRGCHEsc6eeV
  47 TPVFGGILSLINEHRIlngr.PPLGFLNPRLYQQHG...TGL-.....--FDVTHGCHEsc6eeV
  48 TPVFGGILSLINEHRLlsgl.PPLGFLNPRLYQQRG...AGL-.....--FDVTRGCHEsc6eeV
  49 SPHVAGLAALLASQ--.....---GKNNVQIRQAIE...QTA-.....---DKISGTGT.....N
  50 TPHVSGLAAKIWAENP.....---SLSNTQLRSNLQ...ERA-.....KSVDIKGG---.....-
  51 TPHVSGLAAKIWAENP.....---SLSNTQLRSNLQ...ERA-.....KSVDIKGG---.....-
  52 SPTLAGMISLINDKLIgagk.PTLGFLNPLLYQAAK...EQPN.....VFNDITTGANNcnrayC
  53 TPHVAGVAALLANQ--.....---GYSNTQIRQIIE...STT-.....---DKISGTGT.....Y
  54 TPHVAGAAALILSKHP.....---TWTNAQVRDRLE...STA-.....-----------.....-
  55 SPHAAGLAAKIWAQYP.....---SASNVDVRGELQ...YRA-.....YENDILSG---.....-
  56 TPHVAGVAVLLANQ--.....---GYSNTQIRQIIE...STT-.....---DKISGTGT.....Y
  57 SPIFAGVVGLLNDYVNsktg.KPLGFVSPLLYKMAA...ERPA.....AFFDVIKGDNI.....C
  58 APHVSGVAALVISAANs....IGKTLTPSELSDILV...RTTS.....RFNG-------.....-
  59 APHVAGAVALYLDENP.....---SLSPSQIDSLLS...QRSSkg...KVSNPQSGSP-.....-
  60 TPHIAGLGAYLLALE-.....---GGSASTICARIQtl.STKN.....AISGVPSGTVN.....Y
  61 TPHVSGTVALIQAARL.....-AAGLPLLPPGSESD...TTPD.....TVRGVLHTTAT.....D
  62 TPHIAGLGAYLLALE-.....---GGSASTICARIQtl.STKN.....AISGVPSGTVN.....Y
  63 APLTAGRAAIRGDQVT.....----------PAYVY...TGGI.....QFRDITQGSNG.....H
  64 TPHIAGLAAYFSALSG.....---KTSPAALCQKIQdt.STKN.....VIRNVPAGTVN.....F
  65 TPHVAGVAGLLASQ--.....---GRSASNIRAAIE...NTA-.....---DKISGTGT.....Y
  66 TPHIAGLAAYLSALQG.....---KTTPAALCKKIQ...DTATkn...VLTGVPSGTVN.....Y
  67 SPHVAGLAALLASQ--.....---GRNNIEIRQAIE...QTA-.....---DKISGTGT.....Y
  68 TPHVAGVAGLLASQ--.....---GRSASNIRAAIE...NTA-.....---DKISGTGT.....Y
  69 SPHVAGLAALLASQ--.....---GRNNIEIRQAIE...QTA-.....---DKISGTGT.....Y
  70 ----------------.....---------------...----.....-----------.....-
  71 SPHAAGLAAKIWAQSP.....---AASNVDVRGELQ...TRA-.....SVNDILSGN--.....-
  72 APHVSGVAALVISAANs....IGKTLTPSELSDILV...RTTS.....RFNG-------.....-
  73 TPHVSGVATLVWSYHP.....---ECSASQVRAALN...ATAD.....DL---------.....-
  74 TPHIVGLGAYLAGLE-.....---GFPGAQALCKRIqtlSTKN.....VLTGIPSGTVN.....Y
  75 TPHVSGVAGLVWSYHP.....---QCSAKQIRQALT...QTA-.....-----------.....-
  76 APMTAAMVALAGTR--.....--LGALNFALYHISY...QGIIe11kvAWIPITSGNNP.....L
  77 SPHVAGVVALVQSVAP.....--TALTPAAVETLLK...NTAR.....ALPGACSG---.....-
  78 SAFVSGAAALVKAAHP.....---DLTPAQVKSVLE...DTA-.....--RNAPAG---.....-
  79 CPHASGVAALLKAAHP.....---EWSPAAIRSAMM...TTA-.....--NPLDNTLNP.....I
  80 TPHIVGLGAYLSSLEGf....PGAQALCERIRSLAI...RNT-.....-----------.....-
  81 SPHICGLLAYYLSLQPag6efSVASITPKQLKDTLIei.STQG.....VLTDIPNDTPN.....-
  82 SPHICGLLAYYLSLQPag6efSVASITPKQLKDTLIei.STQG.....VLTDIPNDTPN.....-
  83 SPHVAGLGAYFLGLGQ.....KVQGL----------...----.....-----------.....-
  84 SPHIAGAVAVIKQAKP.....---KWSVEQIKAAIM...NTAV.....TLKD-------.....-
  85 TPHIAGLGAYLLALG-.....---KGTAGNLCQTIQtl.STKN.....VLTGVPSGTVN.....Y
  86 APVVAGLLALMQGERQ.....-AAGGENAVTAHAHD...ISGI.....ALNQPFTG---.....-
  87 TPSTSGAMALLMSAYP.....---DLSVRDLRDLLA...RSATrv8qpVMVSYTSSTGKvr7glE
  88 TPHIVGLSVYLMGLEN.....---LSGP--------...----.....-----------.....-
  89 SPFVAGSEALILQGIKk....QGLNLSGEELVQFAK...NSA-.....-----MNTSHP.....V
  90 TPHVVGLSLYLIALEG.....---LSSASAVVSRIK...E---.....-----------.....-
  91 TPHIVGLSVYLMGLENl....----SGPA-------...----.....-----------.....-
  92 SPHVAGTAALVQSALIad...GKAPLTPAALERLLK...RSAR.....AF---------.....-
  93 TPHIVGLSVYLMGLENl....----SGPA-------...----.....-----------.....-
  94 TPHIAGLGAYLAAKNG.....---RRAGPGLCRTIK...----.....-----------.....-
  95 TGKVSGELAEIISNYH.....--LQGDSSKARSILL...NQVN.....-----------.....-
  96 TPHIAGVAALLAEEHP.....---DWSGARLKDALM...STSK.....-ELDVS-----.....-
  97 GPYTAATAALILGAHP.....---ELDPYQVRRLME...ETA-.....---DGSVGENP.....N
  98 APHATGALALVMERYP.....---YLNNEQALQVLL...TTAT.....QLNGAVTDAPT.....T
  99 CPHVAGLASYYLSIND.....--EVLTPAQVEALIT...ESN-.....-----------.....-
 100 TAIASASAALVWSKHP.....---TWTNNQVLRVLI...NTM-.....------KGNEE.....E
 101 SPITAGAVAVLLSAKP.....---GASVDAIKNALF...TSA-.....-----------.....-
 102 APHATGALALVMERYP.....---YMTNEQALQVLL...TTAT.....QLDG-------.....-
 103 TPHVSAAAAVVWAAKP.....---TLTNTQLLNLLT...STAK.....DL---------.....-
 104 APLAAGIYTLVLEANP.....-NLTWRDVQYLSILS...SEEI.....NPHDGKWQDTA.....M
 105 APLASGIYSLILSANP.....-NLTWRDVQYISVLS...ATPI.....NEEDGNYQTT-.....-
 106 ATIFAGIVSLLTDARLragk.PALGFLNPLLYQIAA...EA--.....LMHSVCSG---.....-
 107 TPHVTGAVALLIAEG-.....---NTTTSAVTSALL...NN--.....-----------.....-
 108 RP--------------.....---------------...----.....-----------.....-
 109 APEAAGVFALALEANR.....-NLTWRDMQHLTVLT...SKR-.....--NSLYDSNGI.....H
 110 SPHVAGAAALYLALNP.....---SATPAQVTTAIIna.STPN.....KVTGAQTGSPN.....-
 111 APEAAGVFALALEANK.....-NLTWRDMQHLTVLT...SKR-.....--NSLYDSNGI.....H
 112 APEAAGVFALALEANK.....-NLTWRDMQHLTVLT...SKR-.....--NSLYDSNGI.....H
 113 APEAAGVFALALEANK.....-NLTWRDMQHLTVLT...SKR-.....--NSLYDSNGI.....H


       340       350       360       370  
        |         |         |         |  
   1 GGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNGFGH
   2 GGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNGFGH
   3 GGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNG---
   4 ------TKLGDSFYYGKGLINVQA------------
   5 ------TKLGDSFYYGKGLINVQA------------
   6 ------TKLGDSFYYGKGLINVQA------------
   7 ------TKLGDSFYYGKGLINVQA------------
   8 ------TKLGDSFYYGKGLINVQA------------
   9 ------TKLGDSFYYGKGLINVQA------------
  10 ------TKLGDSFYYGKGLINVQA------------
  11 ------TKLGDSFYYGKGLINVQA------------
  12 ------TYLGDSFYYGKGLINVQA------------
  13 ------TKLGDSFYYGKGLINVQA------------
  14 ------TKLGDSFYYGKGLINVQA------------
  15 ------TKLGDSFYYGKGLINVQA------------
  16 ------TYLGSSFYYGKGLINVQA------------
  17 ------TKLGDSFYYGKGLINVQA------------
  18 ------TKLGDSFYYGKGLINVE-------------
  19 ------TYLGSSFYYGKGLINVQA------------
  20 ------TYLGNSFYYGKGLINVQA------------
  21 ------TKLGDAFYYGKGLINVQA------------
  22 ------TYLGNSFYYGKGLINVQA------------
  23 ------TYLGNSFYYGKGLINVQA------------
  24 ------TYLGNSFYYGKGLINVQA------------
  25 ------TKLGNSFYYGKGLINVQA------------
  26 ------TKLGDSFYYGKGLINVQA------------
  27 ------TKLGDSFYYGKGLINVQA------------
  28 ------TKLGDSFYYGKGLINVE-------------
  29 ------TYLGNSFYYGKGLINVQA------------
  30 ------TYLGNSFYYGKGLINVQA------------
  31 ------TYLGNSFYYGKGLINVQA------------
  32 ------TKLGDSFYYGKGLINVE-------------
  33 ------TYLGNSFYYGKGLINVQA------------
  34 ------TKLGDSFYYGKGLINVQ-------------
  35 ------TYLGSSFYYGKGLINV--------------
  36 ------TYLGSSFYYGKGLINVEA------------
  37 ------TNLGDSFYYGKGLINVE-------------
  38 ------TYLGSSFYYGKGLINVE-------------
  39 ------TYLGSSFYYGKGLINVE-------------
  40 ------TYLGSSFYYGKGLINVE-------------
  41 ------TYLGSSFYYGKGLINVE-------------
  42 QSHGYTAATGFDEATGFGSFDIGKLNTYAQAN----
  43 EGQGFCSGPGWDPVTGWGTPNFPAL-----------
  44 EGQGFCSGPGWDPVTGWGTPNFPAL-----------
  45 ------TYLGSSFYYGKGLINVE-------------
  46 EGQGFCSGPGWDPVTGWGTPNFPAL-----------
  47 EGQGFCSGPGWDPVTGWGTPNFPALL----------
  48 QGQGFCSGPGWDPVTGWGTPNFPAL-----------
  49 FKYG--------------------------------
  50 ----YGAAIGDDYASGFGF-----------------
  51 ----YGAAIGDDYASGFGF-----------------
  52 CQYGYTATTGYDAASGLGSINFKNFEQYVL------
  53 WKN--------------GRVNA--------------
  54 ------TYLGSSFYYG--------------------
  55 ----YYAGYGDDFASGFGF-----------------
  56 WKN--------------GRVNA--------------
  57 TEDGCSS-----------------------------
  58 ---------RLDRGLGSGIVDANA------------
  59 ------------------------------------
  60 ------------------------------------
  61 -----AGDPGYDSLYGYGIIDAYD------------
  62 ------------------------------------
  63 -----SAKAGLDLVTGEG------------------
  64 L-----------------------------------
  65 WAKG--------------------------------
  66 L-----------------------------------
  67 FKYG--------------------------------
  68 WAKG--------------------------------
  69 FKYG--------------------------------
  70 ------------------------------------
  71 -----SAGSGDDIASGFGF-----------------
  72 ---------RLDRGLGSGIVDANA------------
  73 ------SVAGRDNQTGYGMVNATTAKAYL-------
  74 ------------------------------------
  75 -------------------LDLDVLARYIVLD----
  76 -----PAHYGWNYVTGPGTYNAYAM-----------
  77 -------------GCGAGIVNADAAV----------
  78 ---------GRDDSRGFGFVDPA-------------
  79 HENGKKFHLASPLAMGAGHIDPN-------------
  80 ------------------------------------
  81 ------------------------------------
  82 ------------------------------------
  83 ------------------------------------
  84 ------------------------------------
  85 ------------------------------------
  86 -------------GLGYGRIDAA-------------
  87 GWERNAAGMWFSPTYGFGLIDVNK------------
  88 ------------------------------------
  89 YDTEHTKEIISPRRQGSGEIN---------------
  90 ------------------------------------
  91 ------------------------------------
  92 -----PVQIPLATPAGSGIVDAGA------------
  93 ------------------------------------
  94 ------------------------------------
  95 ------------------------------------
  96 -----------AYQLGAGRVS---------------
  97 ---------GFDRGTGYGRIQLGELAQRLQSGPMP-
  98 -------------QVGWGVPDLG-------------
  99 ------------------------------------
 100 WTHNESFGYG--------------------------
 101 -----SNASAKNNNVGFGQISI--------------
 102 -----SITQAPNTVVGWGVPDLG-------------
 103 ------GAAGKDNDFGSGLVN---------------
 104 -------GKRYSHTYGFGKLDAYNIVHMAK------
 105 -----ALNRKYSHKYGYGKTDAYKMVHF--------
 106 -----------------GRKQMQKLSIH--------
 107 ------ATTGKLSSIGTGSPN---------------
 108 ------------------------------------
 109 HWKLNGAHLLFNHLFGYGVLDAAS------------
 110 ------------------------------------
 111 HWKLNGAHLLFNHLFGYGVLDAASM-----------
 112 HWKLNGAHLLFNHLFGYGVLDAASM-----------
 113 HWKLNGAHLLFNHLFGYGVLDAASM-----------