(c) 1992-2000 Regents of the University of California, Santa Cruz
Sequence Alignment and Modeling Software System
http://www.cse.ucsc.edu/research/compbio/sam.html

Citations (SAM, SAM-T99, HMMs)

Sequence numbers correspond to the following labels:

    • T0100 Pectin Methylesterase, E. chrysanthemi
    • gi|5922617|dbj|BAA84618.1|_300:579 (AP000492) EST C97105(C52004) corresponds to a region of the predicted gene.; similar to pectinesterase. (X95991) [Oryza sativa] (Oryza sativa)
    • gi|6016850|dbj|BAA85193.1| (AP000570) EST C97105(C52004) corresponds to a region of the predicted gene.; Similar to pectinesterase. (X95991) [Oryza sativa] (Oryza sativa)
    • gi|7025485|gb|AAF35897.1|AF229849_1_1:246 (AF229849) pectin methylesterase isoform alpha [Vigna radiata] (Vigna radiata)
    • gi|5922617|dbj|BAA84618.1|_301:578 (AP000492) EST C97105(C52004) corresponds to a region of the predicted gene.; similar to pectinesterase. (X95991) [Oryza sativa] (Oryza sativa)
    • gi|6016850|dbj|BAA85193.1| (AP000570) EST C97105(C52004) corresponds to a region of the predicted gene.; Similar to pectinesterase. (X95991) [Oryza sativa] (Oryza sativa)
    • gi|7025485|gb|AAF35897.1|AF229849_1_1:246 (AF229849) pectin methylesterase isoform alpha [Vigna radiata] (Vigna radiata) 
              10        20        30            40         50          
              |         |         |             |          |          
   1 ATTYNAVVSKSSSDGKTFKTIADAIASAPAGS....TPFVILIKNGVYNER.LTIT.....RNNL
   2 DIKANAVVAQDGTG--DYQTLAEAVAAAPDKSk...TRYVIYVKMGIYKEN.VEVTsr...KMNL
   3 AITANVVVANDGSG--KYKTIKEAVASVPDNSn...SRYVIYVKKGIYKEN.VEIGkk...KKNV
   4 AITANVIVAKDGSG--KYKTVKEAVASVPDNSn...SRYVIYVKKGIYKEN.VEIGkk...KKNV
   5 DIIANAVVAQDGTG--DYQTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVAsn...KMNL
   6 DIIANAVVAQDGTG--DYQTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVSsn...KMNL
   7 SVTPNAVVAADGSG--NFKTVAAAVAAAPQGGt...KRYIIRIKAGVYREN.VEVTkk...HKNI
   8 SVTPNAVVAADGSG--NFKTVAAAVAAAPQGGt...KRYIIRIKAGVYREN.VEVTkk...HKNI
   9 DIIANRVVAQDGTG--KYRTLAEAVAAAPNRSk...KRYVIYVKRGIYKEN.VEVSsn...KMNL
  10 -IGANAVVAKDGTG--KYRTLAEAVAAAPDKSk...TRYVIYVKRGIYKEN.VEVSsr...KMKL
  11 -IGANAVVAKDGTG--KYRTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVSsr...KMNL
  12 -IGANAVVAKDGTG--KYRTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVSsr...KMNL
  13 TIKADATVADDGSG--DFTTVAAAVAAAPEKSn...KRFVIHIKAGVYREN.VEVTkk...KTNI
  14 TVTPDVVVAADGSG--DYKTVSEAVAKAPEKSs...KRYVIRIKAGVYREN.VDVPkk...KTNI
  15 -IGANAVVAKDGTG--KYRTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVSsr...KMNL
  16 GVKRDATVAADGSG--TFKTVAAAVAAAPENSn...KRYVIHIKAGVYREN.VEVAkk...KKNI
  17 TVTPDVVVAADGSG--DYKTVSEAVRKAPEKSs...KRYVIRIKAGVYREN.VDVPkk...KTNI
  18 DVKANVVVAQDGSG--KFKTVTEAVASAPDNGk...TRYVIYVKKGTYKEH.VEIGkk...KKNI
  19 -VSVDAIVAQDGTG--NFTNVTDAVLAAPDYSm...RRYVIYIKRGTYKEN.VEIKkk...KWNL
  20 ---DIVTVNQNGTG--NFTTITEAVNSAPNKTdgtaGYFVIYVTSGVYEEN.VVIAkn...KRYL
  21 ---DIVTVSQDGTG--NFTNITAAVAAAPNNTdgsaGFFLIYVTAGIYEEY.ISIAkn...KRYM
  22 -TTYNAVVSKSSSDGKTFKTIADAIASAPAGS....TPFVILIKNGVYNER.LTIT.....RNNL
  23 -TTYNAVVSKSSSDGKTFKTIADAIASAPAGS....TPFVILIKNGVYNER.LTIT.....RNNL
  24 KPKPNVSVAKDGSG--DFKTISEALAAMPAKYe...GRYVIFVKQGVYDET.VTVTkk...MANI
  25 -PKDNAVVAKDGSG--NFKTIKEAIDAAS-GS....GRFVIYVKQGVYSEN.LEIR.....KKNV
  26 --KANVVVAQDGSG--KFKTVTEAVASAPDNGk...TRYVIYVKKGTYKEH.VEIGkk...KKNI
  27 DIIANRVVAQDGTG--DYQTLAEAVAAAPDKNk...TRYVIYVKMGIYKEN.VVVTkk...KMNL
  28 -RTYDVSVALDGTG--NFTKIMDAIKKAPDYSs...TRFVIYIKKGLYLEN.VEIKkk...KWNI
  29 PVKANAVVAQDGTG--QFKTITDALNAVPKGNk...VPFIIHIKEGIYKEK.VTVTkk...MPHV
  30 TIKADATVADDGSG--DFDNGSAAVAAAPEKSn...KRFVIHIKAGVYREN.VEVTkk...KTNI
  31 DIKANVVVAKDGSG--KFKTVAEAVASAPDNGk...ARYVIYVKRGTYKEK.VEIGkk...KTNV
  32 TPRANIVVAQDGSG--NVKTIQEAVAAASRAGg...SRYVIYIKAGTYNEN.IEVK.....LKNI
  33 DIKANVVVAKDGSG--KFKTVAEAVASAPDNGk...ARYVIYVKRGTYKEK.VEIGkk...KTNV
  34 TPRANIVVAQDGSG--NVKTIQEAVAAASRAGg...SRYVIYIKAGTYNEN.IEVK.....LKNI
  35 ETKVNLVVAQNGTG--NYTTIGEAISAAPNSSe...TRFVIYIKCGEYFEN.IEIPre...KTMI
  36 -VRTNFVVAKDGSG--QFKTVQQAVDACPENNr...GRCIIYIKAGLYREQ.VIIPkk...KNNI
  37 ----AVIVGPFKSD--NFTTITDAIAAAPNNTrpedGYFVIYAREGVYEEY.IVVPin...KKNL
  38 -IRATFVVAKDGSG--QFKTVQQAVNACPEKNp...GRCIIHIKAGIYREQ.VIIPkk...KNNI
  39 QIQADIIVSKDGNG--TCKTISEAIKKAPQNSt...RRIIIYVKAGRYEENnLKVGrk...KINL
  40 -IRATFVVAKDGSG--QFKTVQQAVNACPEKNp...GRCIIHIKAGIYREQ.VIIPkk...KNNI
  41 GIKANVVVAKDGSG--KCKTIAQALAMVPMKNt...KKFVIHIKEGVYKEK.VEVTkk...MLHV
  42 -VRTNFVVAKDGSG--QFKTVQQAVDACPENNr...GRCIIYIKAGLYREQ.VIIPkk...KNNI
  43 --VADIVVAKDGSG--KYRTIKRALQDVPEKSe...KRTIIYVKKGVYFEN.VKVEkk...MWNV
  44 NAKPNATVALDGSG--QYKTIKEALDAVPKKNt...EPFIIFIKAGVYKEY.IDIPks...MTNV
  45 KIKATHVVAKDGSG--QFKTISEAVMACPDKNp...GRCIIHIKAGIYNEQ.VRIPkk...KNNI
  46 ALKPNATVAKDGSG--DFTTINDALRAMPEKYe...GRYIIYVKQGIYDEY.VTVDkk...KANL
  47 QPKPNAIVAKDGSG--QFKSIQQAVDAVPKGHq...GRYVIYVKAGLYDEI.VMVPkd...KVNI
  48 KIKPTHVVAKDGSG--QFKTISEAVKACPEKNp...GRCIIYIKAGVYKEQ.VTIPkk...VNNV
  49 DVKPDIVVAQDGSG--QYKTINEALQFVPKKRn...TTFVVHIKAGLYKEY.VQVNkt...MSHL
  50 ---DIVTVIQNGTG--NFTTINAAIAAAPNKTdgsnGYFLIYVTAGLYEEY.VEVPkn...KRYV
  51 -SRADFVVARDGSA--THRTINQALAAVSRMGksrlNRVIIYIKAGVYNEK.IEIDrh...MKNI
  52 --SESLVVAADGTG--NFSTINEAISFAPNMSn...DRVLIYVKEGVYDEN.IDIPiy...KTNI
  53 -TNYNLSVAIDGTG--NFTTINDAVFAAPNMSe...TRFIIYIKGGEYFEN.VELPkk...KTMI
  54 ALKPNATVAKDGSG--NFTTINAALKAMPAKYq...GRYTIYIKHGIYDES.VIIDkk...KPNV
  55 -AKADLVVAKDGSG--HYTSIQQAVNAAAKLPrrn.QRLVIYVKAGVYREN.VVIKks...IKNV
  56 -LNVDAVVAPDGSG--THKTIGEALLSTSLASsg..GRTKIYLKAGTYHEN.INIPtk...QKNV
  57 --HPNTVVAIDGKG--KYRTINEAINEAPNHSt...KRYVIYVKKGVYKEN.IDLKkk...KTNI
  58 --VADAVVAADGTG--NFTTISDAVLAAPDYSt...KRYVIHVKRGVYVEN.VEIKkk...KWNI
  59 KIKPTHVVAKDGSG--QFKTISEAVKACPEKNp...GRCIIYIKAGVYKEQ.VTIPkk...VNNV
  60 --------------------------------....-RYVIRIKAGVYREN.VDVPkk...KTNI
  61 NVQPNAVVAQDGSG--QFKTLTDALKTVPPKNa...VPFVIHVKAGVYKET.VNVAke...MNYV
  62 ELRPHAVVAADGSG--THMSVAEALASLEKGS....GRSVIHLTAGTYKEN.LNIPsk...QKNV
  63 GLKPDVTVAGDGTG--DVLTVNEAVAKVPKKSl...KMFVIYVKSGTYVEN.VVMDks...KWNV
  64 --IADVVVAKDGTG--KYNTVNAAIAAAPQHSh...KRFIIYIKTGIYDEI.VAIEnt...KPNL
  65 --KVDVVVAQDGSG--DYKTIQEAVNGAGERLkgs.PRYVIHVKQGVYEEY.VNVGik...SNNI
  66 NVKANAVVAQDGSG--QFKTLTDALKTVPPTNa...APFVIYVKAGVYKET.VNVAke...MNYV
  67 -STPDAVVAKDGSG--QFKTIGEALKLVKKKSe...ERFSVYVKEGRYVEN.IDLDkn...TWNV
  68 -LKEDVTVCKDGKC--GYKTVQDAVNAAPEDNgm..RKFVIKISEGVYEEN.VIVPfe...KKNV
  69 -SSPHLVVAQDRSG--HFRSIQAAINFAARRRfk..SRFVIYVKKGVYREN.IDVGnd...NHNI
  70 --------------------------------....--------------N.VEIGkk...KKNV
  71 AMRVDVVVAQDGSG--RWRTVSEAVARAPSHSr...RRYVIYVKRGVYEEN.VEVRkk...KTNI
  72 TVKPNVVVAQDGSG--QFKTLTDAIKTVPANNa...QNFVIYVKEGVYNET.VNVPkd...MAFV
  73 --KADLIVAKDGSG--NFTTVNEAVAAAPENGv...KPFVIYIKEGLYKEV.IRIGkk...KTNL
  74 --------------------------------....---------GAYFEN.VEVIrr...KTNL
  75 --IADVVVAKDGTG--KYSTVNAAIAAAPQHSq...KRFVIYIKTGIYDEI.VVIEnt...KPNL
  76 -TSLVLTVDLHGCG--NFSNVQSAIDVVPDLSs...SKTLIIVNSGSYREK.VTVNen...KTNL
  77 -FTMVLKVSLNGCG--RFKRVQDAIDASIGSSq...SKTLILIDFGIYRER.FIVHen...KNNL
  78 --------AKDGSG--KYKTLLEAVASAPDNSk...TRFVIYVKKGTYKEN.VEIGkk...KKNI
  79 ------VVAKDGTG--DYQTLAEAVAAAPDRSk...TRYVIYVKMGIYKEN.VEVTsr...KMNL
  80 -TAILIRVDQSGKG--DFSKIQEAIESIPPNLnns.QLYFIWVKPGIYREK.VVIPae...KPYI
  81 ------VVAKDGSG--KFKTVAEAVASAPDN-....RRYVIYVKKGTYKEN.VEIGkk...KKNV
  82 -ARQIITVNQKGGA--NFKTLNEAIKSIPTGNk...NRVIIKLAPGVYNEK.VTIDia...RPFI
  83 -TTSYLCVDKNGCC--NFTTVQSAVDAVGNFSq...RRNVIWINSGI--EK.VVIPkt...KPNI
  84 --------------------------------kgg.DRFVIRIKEGVYEET.VRAGfy...KTNL
  85 --AGAIVVAKSGGD---YDTLSAAVNALSTTEt...ATQTIFIEEGTYDEQ.VYIPsl...AGKL
  86 -IAKTIIVNPNDAR--YFKTVQSAIDSIPLQNq...DWIRILISNGIYSEK.VTIPrg...KGYI
  87 --SGAIVVAKSGGD---YDTISAAVDALSTTSt...ETQTIFIEEGSYDEQ.VYIPal...SGKL
  88 ---RIINVNPKGGE---FKTLTDAIKSVPAGNt...KRVIIKMAHGEYREK.VTIDrn...KPFI
  89 --------------GGEFKTLTDAIKSVPAGNt...KRVIIKMAPGEYKEK.VTIDrn...KPFI
  90 -SRRVIIVNQNGGG--DFKTINAAIKSIPLANk...NRVIIKLAPGIYHEK.VTVDvg...RPYV
  91 -----GCLSVGSSG--TYKTVSAAVAKLSTSSt...TAQCIFIYKGTYKEQ.VYVPal...KSAL
  92 ---PAGCLTVGGSG--KYKTVQSAVNALDKSTs...KAQCIFIAKGTYTEQ.VYIQql...NSPL
  93 ------TVALDGSG--QYKTIKEALDAVPKKNt...EPFIIFIKAGVYKEY.IDIPks...MTNV
  94 -TNRSIIVDIEGKG--DYTSVQKAIDAVPVGNs...NWIIVHVRKGIYKER.VHIPen...KPFI
  95 --SGAIVVAKSGGD---YTTIGDAIDALSTSTt...DTQTIFIEEGTYDEQ.VYLPam...TGKV
  96 ------VVAKDGSG--QFKTIGEALKLVKKKSe...KRFSVYVKEGRYVEN.IDLDkn...TWNV
  97 ------VVAKDGTG--NFQTVKEAMDAAD-GK....KRFVIYVKAGVYKEK.IHSN.....KDGI
  98 --------------------------------....---------------.----.....----
  99 SVTPNVVVAADGSG--NFKTVAAAVAAAPQGGt...KRYIIRIKAGVYREN.VEVTkk...HKNI
 100 GFRANYAVAADGSA--QYKTVQAAIDAAVADGgv..ARKYISVKAGTYNEL.VCVPes...APPI
 101 --------------------------------....---------------.----.....----
 102 --------------------------------....--------------N.VEVTkk...KMNL
 103 PAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRtn..KRQYIAVMPGEYQGT.VYVPaa...PGGI
 104 PAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRtn..KRQYIAVMPGEYQGT.VYVPaa...PGGI
 105 -TAAYVVGPRAGVAGATHTSIQQAVNAALRQHpgq.TRVYIKLLPGTYTGT.VYVPeg...APPL
 106 QIAYTITVDLNGGG--NFTTVQSAIDSISPPNh...NWIRVFTQNGIYR--.----.....----
 107 -VVNTIVVDQAGSG--KFRTVQAAIDSVGELNs...LWIKIKVKRGVYN--.----.....----
 108 ---ANAVVAQDGTG--DYQTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVAsn...KEFP
 109 --ITDILVAKDVTG--NYNIVNVAIAAAPQHSq...KRFVIYIKTSIYVEI.VVIGnm...KSNL
 110 --------------------------------....---------------.----.....----
 111 --------------------------------....---------------.----.....----
 112 --------------------------------....---------------.----.....----
 113 --------------------------------....---------------.----.....----
 114 ------TVAADGSG--TFKTVAAAVAAAPENSn...KRYVIHIKAGVYREN.VEVAkk...KKNX
 115 HVTANVVVAKDGTG--KFKTVNEAVAAAPENSn...TRYVIYVKKGVYKET.IDIGkk...KKNL
 116 --------------------------------....---------------.----.....----
 117 --------------------------------....---------------.----.....----
 118 ------TVAADGSG--TFKTVAAAVAAAPENSn...KRYVIHIKAGVYREN.VEVAkk...KKNI
 119 --------------------------------....---------------.----.....----
 120 DIKANAVVAQDGTG--DYQTLAEAVAAAPDKSk...TRYVIYVKMGIYKEN.VEVTsr...KMNL
 121 AITANVVVANDGSG--KYKTIKEAVASVPDNSn...SRYVIYVKKGIYKEN.VEIGkk...KKNV
 122 AITANVIVAKDGSG--KYKTVKEAVASVPDNSn...SRYVIYVKKGIYKEN.VEIGkk...KKNV
 123 DIGANAVVAKDGTG--KYRTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVSsr...KMNL
 124 DIGANAVVAKDGTG--KYRTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVSsr...KMNL
 125 DIIANAVVAQDGTG--DYQTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVAsn...KMNL
 126 DIIANAVVAQDGTG--DYQTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVSsn...KMNL
 127 DIGANAVVAKDGTG--KYRTLAEAVAAAPDKSk...TRYVIYVKRGIYKEN.VEVSsr...KMKL
 128 SVTPNAVVAADGSG--NFKTVAAAVAAAPQGGt...KRYIIRIKAGVYREN.VEVTkk...HKNI
 129 SVTPNAVVAADGSG--NFKTVAAAVAAAPQGGt...KRYIIRIKAGVYREN.VEVTkk...HKNI
 130 DIGANAVVAKDGTG--KYRTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVSsr...KMNL
 131 DVKANVVVAQDGSG--KFKTVTEAVASAPDNGk...TRYVIYVKKGTYKEH.VEIGkk...KKNI
 132 DIIANRVVAQDGTG--KYRTLAEAVAAAPNRSk...KRYVIYVKRGIYKEN.VEVSsn...KMNL
 133 TVTPDVVVAADGSG--DYKTVSEAVAKAPEKSs...KRYVIRIKAGVYREN.VDVPkk...KTNI
 134 TIKADATVADDGSG--DFTTVAAAVAAAPEKSn...KRFVIHIKAGVYREN.VEVTkk...KTNI
 135 GVKRDATVAADGSG--TFKTVAAAVAAAPENSn...KRYVIHIKAGVYREN.VEVAkk...KKNI
 136 TVTPDVVVAADGSG--DYKTVSEAVRKAPEKSs...KRYVIRIKAGVYREN.VDVPkk...KTNI
 137 DIKANVVVAKDGSG--KFKTVAEAVASAPDNGk...ARYVIYVKRGTYKEK.VEIGkk...KTNV
 138 DIKANVVVAKDGSG--KFKTVAEAVASAPDNGk...ARYVIYVKRGTYKEK.VEIGkk...KTNV
 139 TIKADATVADDGSG--DFDNGSAAVAAAPEKSn...KRFVIHIKAGVYREN.VEVTkk...KTNI
 140 DIIANRVVAQDGTG--DYQTLAEAVAAAPDKNk...TRYVIYVKMGIYKEN.VVVTkk...KMNL
 141 ----IVTVNQNGTG--NFTTITEAVNSAPNKTdgtaGYFVIYVTSGVYEEN.VVIAkn...KRYL
 142 -PKDNAVVAKDGSG--NFKTIKEAIDAAS-GS....GRFVIYVKQGVYSEN.LEIR.....KKNV
 143 -VSVDAIVAQDGTG--NFTNVTDAVLAAPDYSm...RRYVIYIKRGTYKEN.VEIKkk...KWNL
 144 -PRANIVVAQDGSG--NVKTIQEAVAAASRAGg...SRYVIYIKAGTYNEN.IEVK.....LKNI
 145 ---DIVTVSQDGTG--NFTNITAAVAAAPNNTdgsaGFFLIYVTAGIYEEY.ISIAkn...KRYM
 146 -PRANIVVAQDGSG--NVKTIQEAVAAASRAGg...SRYVIYIKAGTYNEN.IEVK.....LKNI
 147 KPKPNVSVAKDGSG--DFKTISEALAAMPAKYe...GRYVIFVKQGVYDET.VTVTkk...MANI
 148 --KANVVVAQDGSG--KFKTVTEAVASAPDNGk...TRYVIYVKKGTYKEH.VEIGkk...KKNI
 149 -RTYDVSVALDGTG--NFTKIMDAIKKAPDYSs...TRFVIYIKKGLYLEN.VEIKkk...KWNI
 150 -TVADAVVAADGTG--NFTTISDAVLAAPDYSt...KRYVIHVKRGVYVEN.VEIKkk...KWNI
 151 -TTYNAVVSKSSSDGKTFKTIADAIASAPAGS....TPFVILIKNGVYNER.LTIT.....RNNL
 152 -TTYNAVVSKSSSDGKTFKTIADAIASAPAGS....TPFVILIKNGVYNER.LTIT.....RNNL
 153 --HPNTVVAIDGKG--KYRTINEAINEAPNHSt...KRYVIYVKKGVYKEN.IDLKkk...KTNI
 154 PVKANAVVAQDGTG--QFKTITDALNAVPKGNk...VPFIIHIKEGIYKEK.VTVTkk...MPHV
 155 ----IVTVIQNGTG--NFTTINAAIAAAPNKTdgsnGYFLIYVTAGLYEEY.VEVPkn...KRYV
 156 DVKPDIVVAQDGSG--QYKTINEALQFVPKKRn...TTFVVHIKAGLYKEY.VQVNkt...MSHL
 157 ETKVNLVVAQNGTG--NYTTIGEAISAAPNSSe...TRFVIYIKCGEYFEN.IEIPre...KTMI
 158 -VRTNFVVAKDGSG--QFKTVQQAVDACPENNr...GRCIIYIKAGLYREQ.VIIPkk...KNNI
 159 QPKPNAIVAKDGSG--QFKSIQQAVDAVPKGHq...GRYVIYVKAGLYDEI.VMVPkd...KVNI
 160 --SESLVVAADGTG--NFSTINEAISFAPNMSn...DRVLIYVKEGVYDEN.IDIPiy...KTNI
 161 ----AVIVGPFKSD--NFTTITDAIAAAPNNTrpedGYFVIYAREGVYEEY.IVVPin...KKNL
 162 -IRATFVVAKDGSG--QFKTVQQAVNACPEKNp...GRCIIHIKAGIYREQ.VIIPkk...KNNI
 163 -IRATFVVAKDGSG--QFKTVQQAVNACPEKNp...GRCIIHIKAGIYREQ.VIIPkk...KNNI
 164 -VRTNFVVAKDGSG--QFKTVQQAVDACPENNr...GRCIIYIKAGLYREQ.VIIPkk...KNNI
 165 QIQADIIVSKDGNG--TCKTISEAIKKAPQNSt...RRIIIYVKAGRYEENnLKVGrk...KINL
 166 KIKATHVVAKDGSG--QFKTISEAVMACPDKNp...GRCIIHIKAGIYNEQ.VRIPkk...KNNI
 167 NAKPNATVALDGSG--QYKTIKEALDAVPKKNt...EPFIIFIKAGVYKEY.IDIPks...MTNV
 168 GIKANVVVAKDGSG--KCKTIAQALAMVPMKNt...KKFVIHIKEGVYKEK.VEVTkk...MLHV
 169 --VADIVVAKDGSG--KYRTIKRALQDVPEKSe...KRTIIYVKKGVYFEN.VKVEkk...MWNV
 170 KIKPTHVVAKDGSG--QFKTISEAVKACPEKNp...GRCIIYIKAGVYKEQ.VTIPkk...VNNV
 171 -SRADFVVARDGSA--THRTINQALAAVSRMGksrlNRVIIYIKAGVYNEK.IEIDrh...MKNI
 172 ALKPNATVAKDGSG--NFTTINAALKAMPAKYq...GRYTIYIKHGIYDES.VIIDkk...KPNV
 173 -AKADLVVAKDGSG--HYTSIQQAVNAAAKLPrrn.QRLVIYVKAGVYREN.VVIKks...IKNV
 174 ALKPNATVAKDGSG--DFTTINDALRAMPEKYe...GRYIIYVKQGIYDEY.VTVDkk...KANL
 175 TVKPNVVVAQDGSG--QFKTLTDAIKTVPANNa...QNFVIYVKEGVYNET.VNVPkd...MAFV
 176 -LNVDAVVAPDGSG--THKTIGEALLSTSLASsg..GRTKIYLKAGTYHEN.INIPtk...QKNV
 177 --------------------------------....-RYVIRIKAGVYREN.VDVPkk...KTNI
 178 -LRPHAVVAADGSG--THMSVAEALASLEKGS....GRSVIHLTAGTYKEN.LNIPsk...QKNV
 179 KIKPTHVVAKDGSG--QFKTISEAVKACPEKNp...GRCIIYIKAGVYKEQ.VTIPkk...VNNV
 180 -LKEDVTVCKDGKC--GYKTVQDAVNAAPEDNgm..RKFVIKISEGVYEEN.VIVPfe...KKNV
 181 GLKPDVTVAGDGTG--DVLTVNEAVAKVPKKSl...KMFVIYVKSGTYVEN.VVMDks...KWNV
 182 NVQPNAVVAQDGSG--QFKTLTDALKTVPPKNa...VPFVIHVKAGVYKET.VNVAke...MNYV
 183 -TNYNLSVAIDGTG--NFTTINDAVFAAPNMSe...TRFIIYIKGGEYFEN.VELPkk...KTMI
 184 --IADVVVAKDGTG--KYNTVNAAIAAAPQHSh...KRFIIYIKTGIYDEI.VAIEnt...KPNL
 185 DSTPDAVVAKDGSG--QFKTIGEALKLVKKKSe...ERFSVYVKEGRYVEN.IDLDkn...TWNV
 186 NVKANAVVAQDGSG--QFKTLTDALKTVPPTNa...APFVIYVKAGVYKET.VNVAke...MNYV
 187 --KVDVVVAQDGSG--DYKTIQEAVNGAGERLkgs.PRYVIHVKQGVYEEY.VNVGik...SNNI
 188 -SSPHLVVAQDRSG--HFRSIQAAINFAARRRfk..SRFVIYVKKGVYREN.IDVGnd...NHNI
 189 -MRVDVVVAQDGSG--RWRTVSEAVARAPSHSr...RRYVIYVKRGVYEEN.VEVRkk...KTNI
 190 --------------------------------....--------------N.VEIGkk...KKNV
 191 --KADLIVAKDGSG--NFTTVNEAVAAAPENGv...KPFVIYIKEGLYKEV.IRIGkk...KTNL
 192 --IADVVVAKDGTG--KYSTVNAAIAAAPQHSq...KRFVIYIKTGIYDEI.VVIEnt...KPNL
 193 --------------------------------....---------GAYFEN.VEVIrr...KTNL
 194 -----------------------------KGG....DRFVIRIKEGVYEET.VRAGfy...KTNL
 195 -FTMVLKVSLNGCG--RFKRVQDAIDASIGSSq...SKTLILIDFGIYRER.FIVHen...KNNL
 196 --------AKDGSG--KYKTLLEAVASAPDNSk...TRFVIYVKKGTYKEN.VEIGkk...KKNI
 197 ------VVAKDGTG--DYQTLAEAVAAAPDRSk...TRYVIYVKMGIYKEN.VEVTsr...KMNL
 198 -ARQIITVNQKGGA--NFKTLNEAIKSIPTGNk...NRVIIKLAPGVYNEK.VTIDia...RPFI
 199 ------VVAKDGSG--KFKTVAEAVASAPDNR....R-YVIYVKKGTYKEN.VEIGkk...KKNV
 200 DTTSYLCVDKNGCC--NFTTVQSAVDAVGNFSq...RRNVIWINSGI--EK.VVIPkt...KPNI
 201 -TAILIRVDQSGKG--DFSKIQEAIESIPPNLnns.QLYFIWVKPGIYREK.VVIPae...KPYI
 202 -TSLVLTVDLHGCG--NFSNVQSAIDVVPDLSs...SKTLIIVNSGSYREK.VTVNen...KTNL
 203 -TNRSIIVDIEGKG--DYTSVQKAIDAVPVGNs...NWIIVHVRKGIYKER.VHIPen...KPFI
 204 ---RIINVNPKGGE---FKTLTDAIKSVPAGNt...KRVIIKMAHGEYREK.VTIDrn...KPFI
 205 -IAKTIIVNPNDAR--YFKTVQSAIDSIPLQNq...DWIRILISNGIYSEK.VTIPrg...KGYI
 206 --SGAIVVAKSGGD---YDTISAAVDALSTTSt...ETQTIFIEEGSYDEQ.VYIPal...SGKL
 207 ------------GG--EFKTLTDAIKSVPAGNt...KRVIIKMAPGEYKEK.VTIDrn...KPFI
 208 -SRRVIIVNQNGGG--DFKTINAAIKSIPLANk...NRVIIKLAPGIYHEK.VTVDvg...RPYV
 209 ------TVALDGSG--QYKTIKEALDAVPKKNt...EPFIIFIKAGVYKEY.IDIPks...MTNV
 210 --AGAIVVAKSGGD---YDTLSAAVNALSTTEt...ATQTIFIEEGTYDEQ.VYIPsl...AGKL
 211 --------------------------------....---------------.----.....----
 212 -----GCLSVGSSG--TYKTVSAAVAKLSTSSt...TAQCIFIYKGTYKEQ.VYVPal...KSAL
 213 ------VVAKDGSG--QFKTIGEALKLVKKKSe...KRFSVYVKEGRYVEN.IDLDkn...TWNV
 214 ------VVAKDGTG--NFQTVKEAMDAAD-GK....KRFVIYVKAGVYKEK.IHSN.....KDGI
 215 --SGAIVVAKSGGD---YTTIGDAIDALSTSTt...DTQTIFIEEGTYDEQ.VYLPam...TGKV
 216 SVTPNVVVAADGSG--NFKTVAAAVAAAPQGGt...KRYIIRIKAGVYREN.VEVTkk...HKNI
 217 GFRANYAVAADGSA--QYKTVQAAIDAAVADGgv..ARKYISVKAGTYNEL.VCVPes...APPI
 218 --------------------------------....---------------.----.....----
 219 --------------------------------....--------------N.VEVTkk...KMNL
 220 --APAGCLTVGGSG--KYKTVQSAVNALDKSTs...KAQCIFIAKGTYTEQ.VYIQql...NSPL
 221 PAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRtn..KRQYIAVMPGEYQGT.VYVPaa...PGGI
 222 PAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRtn..KRQYIAVMPGEYQGT.VYVPaa...PGGI
 223 -TAAYVVGPRAGVAGATHTSIQQAVNAALRQHpgq.TRVYIKLLPGTYTGT.VYVPeg...APPL
 224 --IANAVVAQDGTG--DYQTLAEAVAAAPDKSk...TRYVIYVKRGTYKEN.VEVAsn...KEFP
 225 QIAYTITVDLNGGG--NFTTVQSAIDSISPPNh...NWIRVFTQNGIYRM-.----.....----
 226 -VVNTIVVDQAGSG--KFRTVQAAIDSVGELNs...LWIKIKVKRGVYN--.----.....----
 227 --ITDILVAKDVTG--NYNIVNVAIAAAPQHSq...KRFVIYIKTSIYVEI.VVIGnm...KSNL
 228 --------------------------------....---------------.----.....----
 229 --------------------------------....---------------.----.....----
 230 --------------------------------....---------------.----.....----
 231 ------TVAADGSG--TFKTVAAAVAAAPENSn...KRYVIHIKAGVYREN.VEVAkk...KKNX
 232 --------------------------------....---------------.----.....----
 233 HVTANVVVAKDGTG--KFKTVNEAVAAAPENSn...TRYVIYVKKGVYKET.IDIGkk...KKNL
 234 ------TVAADGSG--TFKTVAAAVAAAPENSn...KRYVIHIKAGVYREN.VEVAkk...KKNI
 235 --------------------------------....---------------.----.....----
 236 --------------------------------....---------------.----.....----
 237 --------------------------------....---------------.----.....----
 238 --------------------------------....---------------.----.....----
 239 -----------SGQ--IYTSIQAAIDNSSTLE....G-DVINVHGGTYHED.VTVN.....KKLI
 240 NPKTWYVDDDGQNCSADFASIQDAVNASIDGD....T---IVVCNGTYVEN.IVVNr....TLNI
 241 CITVAKVMNLDTNR--TFDRIQDAINDNSTVA....G-HTILVGEGNYTEN.IVLN.....KP-L
 242 --------QNEGTKEKPFRTLAHASEKAAAGT....T---VMIREGTYHET.LDVKhsgtdGKPI
 243 --------------------------------....---------------.----.....----
 244 CITVAKVMNLDTNR--TFDRIQDAINDNSTVA....G-HTILVGEGNYTEN.IVLN.....KP-L
 245 ---SATVVNLNTTE--EFSTIQEAIDNSTDGH....H---LIVNSGTYNEN.VLVN.....KT-L


             60        70         80               90             100  
             |         |          |                |               |  
   1 HLK..G..ESRNGAVIAAATAAGTL.KSDGS.....KW..GTAGSSTI.....TISAK.DFSAQS
   2 MIV..G..DGMNATIITGSLNY---.---VD.....GT..TTFRSATL.....AAVGQ.GFILQD
   3 MLV..G..DGMDATIITGNLNV---.---VD.....GA..TTFNSATV.....AAVGD.GFIAQD
   4 MLV..G..DGMDATIITGNLNV---.---VD.....GA..TTFNSATV.....AAVGD.GFIAQD
   5 MIV..G..DGMYATTITGSLNV---.---VD.....GS..TTFRSATL.....AAVGQ.GFILQD
   6 MIV..G..DGMYATTITGSLNV---.---VD.....GS..TTFRSATL.....AAVGQ.GFILQD
   7 MFI..G..DGRTRTIITGSRNV---.---VD.....GS..TTFKSATV.....AVVGE.GFLARD
   8 MFI..G..DGRTRTIITGSRNV---.---VD.....GS..TTFKSATA.....AVVGE.GFLARD
   9 MIV..G..DGMYATTITGSLNV---.---VD.....GS..TTFRSATL.....AAVGQ.GFILQD
  10 MIV..G..DGMHATIITGNLNV---.---VD.....GS..TTFHSATL.....AAVGK.GFILQD
  11 MII..G..DGMYATIITGSLNV---.---VD.....GS..TTFHSATL.....AAVGK.GFILQD
  12 MII..G..DGMYATIITGSLNV---.---VD.....GS..TTFHSATL.....AAVGK.GFILQD
  13 MFL..G..DGRGKTIITGSRNV---.---VD.....GS..TTFHSATV.....AAVGE.RFLARD
  14 MFM..G..DGRSNTIITASRNV---.---QD.....GS..TTFHSATV.....AAVGE.KFLARD
  15 MII..G..DGMYATIITGSLNV---.---VD.....GS..TTFHSATL.....AAVGK.GFILQD
  16 MFM..G..DGRTRTIITGSRNV---.---VD.....GS..TTFHSATV.....AAVGE.RFLARD
  17 MFM..G..DGKSNTIITASRNV---.---QD.....GS..TTFHSATV.....VRVAG.KVLARD
  18 MLV..G..DGMDATIITGSLNF---.---ID.....GT..TTFNSATV.....AAVGD.GFIGQD
  19 MMI..G..DGMDATIISGNRSF---.---VD.....GW..TTFRSATF.....AVSGR.GFIARD
  20 MMI..G..DGINRTVVTGNRNV---.---VD.....GW..TTFNSATF.....AVTSP.NFVAVN
  21 MMI..G..DGINQTVVTGNRSV---.---VD.....GW..TTFNSATF.....AVTAP.NFVAVN
  22 LLK..G..ESRNGAVIAAATAAGTL.KSDGS.....KW..GTAGSSTI.....TISAK.DFSAQS
  23 HLK..G..ESRNGAVIAAATAAGTL.KSDGS.....KW..GTAGSSTI.....TISAK.DFSAQS
  24 TMY..G..DGSQKTIVTGNKNF---.---AD.....GV..QTFRTATF.....AVLGD.GFLCKF
  25 MLR..G..DGIGKTIITGSKSV---.---GG.....GT..TTFNSATV.....AAVGD.GFIARG
  26 MLV..G..DGMDATIITGSLNF---.---ID.....GT..TTFNSATV.....AAVGD.GFIGQD
  27 MIV..G..DGMNATIITGSLNV---.---V-.....DG..STFPSNTL.....AAVGQ.GFILQD
  28 VML..G..DGIDVTVISGNRSF---.---ID.....GW..TTFRSATF.....AVSGR.GFLARD
  29 TFI..G..DGPNKTLITGSLNFG--.---IG.....KV..KTFLTATI.....TIEGD.HFTAKN
  30 MFL..G..DGRGKTIITGSRNV---.---VD.....GS..TTFHSATV.....AAVGE.RFLARD
  31 MLV..G..DGMDATIITGNLNF---.---ID.....GT..TTFNSATV.....AAVGD.GFIAQD
  32 MFV..G..DGIGKTIITGSKSV---.---GG.....GA..TTFKSATV.....AVVGD.NFIARD
  33 MLV..G..DGMDATIITGNLNF---.---ID.....GT..TTFNSATV.....AAVGD.GFIAQD
  34 MFV..G..DGIGKTIITGSKSV---.---GG.....GA..TTFKSATV.....AVVGD.NFIARD
  35 MFI..G..DGIGRTVIKANRSY---.---AD.....GW..TAFHSATV.....GVRGS.GFIAKD
  36 FMF..G..DGARKTVISYNRSVAL-.---SR.....GT..TTSLSATV.....QVESE.GFMAKW
  37 MLM..G..DGINKTIITGNHNV---.---VD.....GW..TTYNCSSF.....AVVGE.RFMAVD
  38 FMF..G..DGARKTVISYNRSVKL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
  39 MFV..G..DGKGKTVISGGKSI---.---FD.....NI..TTFHTASF.....AATGA.GFIARD
  40 FMF..G..DGARKTVISYNRSVKL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
  41 MFV..G..DGPTKTVITGDIAFL--.---PD.....QV..GTYRTASV.....AVNGD.YFMAKD
  42 FMF..G..DGARKTVISYNRSV---.---AL.....SR..GTTTSLSA.....TVESE.GFMAKW
  43 IVV..G..DGESKSIVSGRLNV---.---ID.....GT..PTFKTATF.....AVFGK.GFMARD
  44 VLI..G..EGPTKTKITGNKSV---.---KD.....GP..STFHTTTV.....GVNGA.NFVAKN
  45 FMF..G..DGATQTIITFDRSVKL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
  46 TMV..G..DGSQKTIVTGNKSH---.---AK.....KI..RTFLTATF.....VAQGE.GFMAQS
  47 FMY..G..DGPKQSRVTGRKSF---.---AD.....GI..TTMKTATF.....SVEAS.GFICKN
  48 FMF..G..DGATQTIITFDRSVGL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
  49 VFI..G..DGPDKTIISGNKNY---.---KD.....GI..TTYRTATV.....AIVGN.YFIAKN
  50 MMI..G..DGINQTVITGNRSV---.---VD.....GW..TTFNSATF.....ILSGP.NFIGVN
  51 MLV..G..DGMDRTIVTNNRNV---.---PD.....GS..TTYGSATF.....GVSGD.GFWARD
  52 VLI..G..DGSDVTFITGNRSV---.---GD.....GW..TTFRSATL.....AVSGE.GFLARD
  53 MFI..G..DGIGKTVIKANRSR---.---ID.....GW..STFQTPTV.....GVKGK.GYIAKD
  54 TMV..G..DGSQKTIVTGNKSH---.---AK.....KI..RTFLTATF.....VAQGE.GFMAQS
  55 MVI..G..DGIDSTIVTGNRNV---.---QD.....GT..TTFRSATF.....AVSGN.GFIAQG
  56 MLV..G..DGKGKTVIVGSRSN---.---RG.....GW..TTYKTATV.....AAMGE.GFIARD
  57 MLV..G..DGIGQTIITGDRNF---.---MQ.....GL..TTFRTATV.....AVSGR.GFIAKD
  58 MMV..G..DGIDATVITGNRSF---.---ID.....GW..TTFRSATF.....AVSGR.GFIARD
  59 FMF..G..DGATQTIITFDRSVGL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
  60 MFM..G..DGRSNTIITGSRNV---.---KD.....GS..TTFNSATV.....AAVGE.KFLARD
  61 TVI..G..DGPTKTKFTGSLNY---.---AD.....GI..NTYNTATF.....GVNGA.NFMAKD
  62 MLV..G..DGKGKTVIVGSRSN---.---RG.....GW..NTYQSATV.....AAMGD.GFIARD
  63 MIY..G..DGKGKTIISGSKNF---.---VD.....GT..PTYETATF.....AIQGK.GFIMKD
  64 TLI..G..DGQDSTIITGNLSA---.---SN.....VR..RTFYTATFd11feASNGK.GFIGVD
  65 MIT..G..DGIGKTIITGDKSK---.---GR.....GF..STYKSATF.....VAEGD.GFVGRD
  66 TVI..G..DGPTKTKFTGSLNY---.---AD.....GI..NTYKTATF.....GVNGA.NFMAKD
  67 MIY..G..DGKDKTFVVGSRNF---.---MD.....GT..PTFETATF.....AVKGK.GFIAKD
  68 VFI..G..DGMGKTVITGSLNAG--.---MP.....GI..TTYNTATV.....GVVGD.GFMARD
  69 MLV..G..DGERKTIITSGRSV---.---QH.....GY..TTYNSATG.....GFGGQ.RFVAKD
  70 MLV..G..DGMDATIITGNLNV---.---VD.....GA..TTFNSATV.....AAVGD.GFIAQD
  71 VIV..G..EGMGETVITGSRSM---.---AA.....GW..TTFRSATF.....AVSGA.GFIARD
  72 TII..G..DGPAKTKFTGSLNY---.---AD.....GL..LPYNTATL.....GVNGE.NFMAKD
  73 TLV..G..DGRDLTVLSGDLNG---.---VD.....GI..KTFDSATL.....AVDES.GFMAQD
  74 MWV..G..DGIGKTVVKASRNV---.---VD.....GW..TTFQSATV.....AVVGD.GFIAKG
  75 TLI..G..DGQDLTIITSNLSA---.---SN.....VR..RTFNTATVg27feASNGN.GFIGVD
  76 VIQ..G..RGYQNTSIEWNDTA---.---KS.....AG..NTADSFSF.....VVFAA.NFTAYN
  77 VVQ..G..MGYSRTSIEWNNTT---.---AS.....SN..GTFSSFSV.....AVFGE.KFTAYN
  78 MLV..G..DGMDATIITGNLNV---.---ID.....GS..TTFKSATV.....AAVGD.GFIAQD
  79 MIV..G..DGMNATIITGSLNF---.---VD.....GT..TTFRSATL.....AAVGQ.GFILQD
  80 TLS..G..TQASNTFLIW-------.---SD.....GE..DILESPTL.....TIFAS.DFVCRF
  81 MLV..G..DGKDLTVITGSLNY---.---ID.....GT..GTFQTATV.....AAVGD.GFIGQD
  82 TLL..G..QPGAETVLTYHGTA---.----A.....QY..GTVESATL.....IVWAE.YFQAAH
  83 TLQ..G..QGFDITAIAWNDTA---.---YS.....AN..GTFYCATV.....QVFGS.QFVAKN
  84 VFL..G..DGMGKTVITGSISTG--.---IT.....RI..TTYNTATV.....GILGD.GFMASG
  85 IIY..G..QTEDDTTYTGNLVNITH.NIKLA.....DVa.NDDETATV.....RNHSP.NSSIYN
  86 YMQ..G..GGIEKTIIAY-------.---GD.....HQ..LTNTSATF.....TSYPS.NIIITG
  87 IVY..G..QTEDTTTYTSNLVNITH.AIALA.....DVd.NDDETATL.....RNYAE.GSAIYN
  88 TLM..G..QPNAMPVITYDGTA---.----A.....KY..GTVDSASL.....IILSD.YFMAVN
  89 TLM..G..QPNAMPVITYDGTA---.----A.....KY..GTVDSASL.....IILSD.YFMAVN
  90 TLL..G..KPGAETNLTYAGTA---.----A.....KY..GTVESATL.....IVWAT.NFLAAN
  91 TIY..G..ETTDTSGFASNTVTITQ.GKSQD.....DVs.GNDLTATL.....RAWTP.NLKVYN
  92 TIY..G..ETKDTRSYSGNTVTITQ.RKSQN.....DTp.SNDETATL.....RAHTP.NLKVYN
  93 VLI..G..EGPTKTKITGNKSV---.---KD.....GP..STFHTTTV.....GVNGA.NFVAKN
  94 FMR..G..NGKGKTVIESS------.---QS.....SV..DNVASATF.....KVEAN.HFVAFG
  95 IIY..G..QTENTDSYADNLVTITH.AISYE.....DAgeSDDLTATF.....RNKAV.GSQVYN
  96 MIY..G..DGKDKTFVLGSRNF---.---MD.....GT..PTFETATF.....AVKGK.GFIAKD
  97 TLI..G..DGKYSTIIVGDDSV---.---AG.....GS..TMPGSATI.....TMTGD.GFIARD
  98 ---..-..-----------------.-----.....--..--------.....-----.--MAQD
  99 MFI..G..DGRTRTIITGSRNV---.---VD.....GS..TTFKSATV.....-----.------
 100 TLYslD..ANANNTVIVYNNANPTP.ASGAKt11naTV..GTVRSATA.....MVRAS.NFNARN
 101 ---..-..-----------------.-----.....--..--------.....-IDGN.WFMAQD
 102 MIV..G..DGMNSTVITGSLNV---.---VD.....GS..TTFRSATL.....AAVGQ.GFILQD
 103 TLY..G..TGEKPIDVKIGLSLDGG.MSPADw30sdSI..GVLCSAVF.....WSQNN.GLQLQN
 104 TLY..G..TGEKPIDVKIGLSLDGG.MSPADw30sdSI..GVLCSAVF.....WSQNN.GLQLQN
 105 TLF..G..AGDRPEQVVVSLALDSM.MSPADy30gaTI..NTTCSAVM.....WSQSN.DFQLKN
 106 ---..-..-----------------.-----.....--..--------.....-----.------
 107 ---..-..--------TYNRLT---.-----.....--..--------.....-----.-----S
 108 TYL..G..RPWKEYSRTVVMES---.----Y.....LG..GLINPAGW.....AEWDG.DFALKT
 109 TLI..A..DGQDSTIITFNLSS---.---SN.....SK..RTFNTATF.....-----.GKNLVD
 110 ---..-..-----------------.--TAC.....GG..QTPNSARF.....QPVFP.GTVSRP
 111 ---..-..-----------------.-----.....--..--------.....-----.------
 112 ---..-..-----------------.-----.....--..--------.....-----.------
 113 ---..-..-----------------.-----.....--..--------.....-----.------
 114 MFM..G..DGRTRTIITGSRNV---.---VD.....GS..TTFHSATV.....AAVRE.KFLTRD
 115 MLV..G..DGKDATIITGSLNV---.---ID.....GS..TTFRSATV.....-----.------
 116 ---..-..-----------------.-----.....--..--------.....-----.------
 117 ---..-..-----------------.-----.....--..--------.....-----.------
 118 MFM..G..DGRTRTIITGSRNV---.---VD.....GS..TTFHSATV.....AAV--.------
 119 ---..-..-----------------.-----.....--..--------.....-----.------
 120 MIV..G..DGMNATIITGSLNY---.---VD.....GT..TTFRSATL.....AAVGQ.GFILQD
 121 MLV..G..DGMDATIITGNLNV---.---VD.....GA..TTFNSATV.....AAVGD.GFIAQD
 122 MLV..G..DGMDATIITGNLNV---.---VD.....GA..TTFNSATV.....AAVGD.GFIAQD
 123 MII..G..DGMYATIITGSLNV---.---VD.....GS..TTFHSATL.....AAVGK.GFILQD
 124 MII..G..DGMYATIITGSLNV---.---VD.....GS..TTFHSATL.....AAVGK.GFILQD
 125 MIV..G..DGMYATTITGSLNV---.---VD.....GS..TTFRSATL.....AAVGQ.GFILQD
 126 MIV..G..DGMYATTITGSLNV---.---VD.....GS..TTFRSATL.....AAVGQ.GFILQD
 127 MIV..G..DGMHATIITGNLNV---.---VD.....GS..TTFHSATL.....AAVGK.GFILQD
 128 MFI..G..DGRTRTIITGSRNV---.---VD.....GS..TTFKSATV.....AVVGE.GFLARD
 129 MFI..G..DGRTRTIITGSRNV---.---VD.....GS..TTFKSATA.....AVVGE.GFLARD
 130 MII..G..DGMYATIITGSLNV---.---VD.....GS..TTFHSATL.....AAVGK.GFILQD
 131 MLV..G..DGMDATIITGSLNF---.---ID.....GT..TTFNSATV.....AAVGD.GFIGQD
 132 MIV..G..DGMYATTITGSLNV---.---VD.....GS..TTFRSATL.....AAVGQ.GFILQD
 133 MFM..G..DGRSNTIITASRNV---.---QD.....GS..TTFHSATV.....AAVGE.KFLARD
 134 MFL..G..DGRGKTIITGSRNV---.---VD.....GS..TTFHSATV.....AAVGE.RFLARD
 135 MFM..G..DGRTRTIITGSRNV---.---VD.....GS..TTFHSATV.....AAVGE.RFLARD
 136 MFM..G..DGKSNTIITASRNV---.---QD.....GS..TTFHSATV.....VRVAG.KVLARD
 137 MLV..G..DGMDATIITGNLNF---.---ID.....GT..TTFNSATV.....AAVGD.GFIAQD
 138 MLV..G..DGMDATIITGNLNF---.---ID.....GT..TTFNSATV.....AAVGD.GFIAQD
 139 MFL..G..DGRGKTIITGSRNV---.---VD.....GS..TTFHSATV.....AAVGE.RFLARD
 140 MIV..G..DGMNATIITGSLNV---.---V-.....DG..STFPSNTL.....AAVGQ.GFILQD
 141 MMI..G..DGINRTVVTGNRNV---.---VD.....GW..TTFNSATF.....AVTSP.NFVAVN
 142 MLR..G..DGIGKTIITGSKSV---.---GG.....GT..TTFNSATV.....AAVGD.GFIARG
 143 MMI..G..DGMDATIISGNRSF---.---VD.....GW..TTFRSATF.....AVSGR.GFIARD
 144 MFV..G..DGIGKTIITGSKSV---.---GG.....GA..TTFKSATV.....AVVGD.NFIARD
 145 MMI..G..DGINQTVVTGNRSV---.---VD.....GW..TTFNSATF.....AVTAP.NFVAVN
 146 MFV..G..DGIGKTIITGSKSV---.---GG.....GA..TTFKSATV.....AVVGD.NFIARD
 147 TMY..G..DGSQKTIVTGNKNF---.---AD.....GV..QTFRTATF.....AVLGD.GFLCKF
 148 MLV..G..DGMDATIITGSLNF---.---ID.....GT..TTFNSATV.....AAVGD.GFIGQD
 149 VML..G..DGIDVTVISGNRSF---.---ID.....GW..TTFRSATF.....AVSGR.GFLARD
 150 MMV..G..DGIDATVITGNRSF---.---ID.....GW..TTFRSATF.....AVSGR.GFIARD
 151 LLK..G..ESRNGAVIAAATAAGTL.KSDGS.....KW..GTAGSSTI.....TISAK.DFSAQS
 152 HLK..G..ESRNGAVIAAATAAGTL.KSDGS.....KW..GTAGSSTI.....TISAK.DFSAQS
 153 MLV..G..DGIGQTIITGDRNF---.---MQ.....GL..TTFRTATV.....AVSGR.GFIAKD
 154 TFI..G..DGPNKTLITGSLNFG--.---IG.....KV..KTFLTATI.....TIEGD.HFTAKN
 155 MMI..G..DGINQTVITGNRSV---.---VD.....GW..TTFNSATF.....ILSGP.NFIGVN
 156 VFI..G..DGPDKTIISGNKNY---.---KD.....GI..TTYRTATV.....AIVGN.YFIAKN
 157 MFI..G..DGIGRTVIKANRSY---.---AD.....GW..TAFHSATV.....GVRGS.GFIAKD
 158 FMF..G..DGARKTVISYNRSVAL-.---SR.....GT..TTSLSATV.....QVESE.GFMAKW
 159 FMY..G..DGPKQSRVTGRKSF---.---AD.....GI..TTMKTATF.....SVEAS.GFICKN
 160 VLI..G..DGSDVTFITGNRSV---.---GD.....GW..TTFRSATL.....AVSGE.GFLARD
 161 MLM..G..DGINKTIITGNHNV---.---VD.....GW..TTYNCSSF.....AVVGE.RFMAVD
 162 FMF..G..DGARKTVISYNRSVKL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
 163 FMF..G..DGARKTVISYNRSVKL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
 164 FMF..G..DGARKTVISYNRSV---.---AL.....SR..GTTTSLSA.....TVESE.GFMAKW
 165 MFV..G..DGKGKTVISGGKSI---.---FD.....NI..TTFHTASF.....AATGA.GFIARD
 166 FMF..G..DGATQTIITFDRSVKL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
 167 VLI..G..EGPTKTKITGNKSV---.---KD.....GP..STFHTTTV.....GVNGA.NFVAKN
 168 MFV..G..DGPTKTVITGDIAFL--.---PD.....QV..GTYRTASV.....AVNGD.YFMAKD
 169 IVV..G..DGESKSIVSGRLNV---.---ID.....GT..PTFKTATF.....AVFGK.GFMARD
 170 FMF..G..DGATQTIITFDRSVGL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
 171 MLV..G..DGMDRTIVTNNRNV---.---PD.....GS..TTYGSATF.....GVSGD.GFWARD
 172 TMV..G..DGSQKTIVTGNKSH---.---AK.....KI..RTFLTATF.....VAQGE.GFMAQS
 173 MVI..G..DGIDSTIVTGNRNV---.---QD.....GT..TTFRSATF.....AVSGN.GFIAQG
 174 TMV..G..DGSQKTIVTGNKSH---.---AK.....KI..RTFLTATF.....VAQGE.GFMAQS
 175 TII..G..DGPAKTKFTGSLNY---.---AD.....GL..LPYNTATL.....GVNGE.NFMAKD
 176 MLV..G..DGKGKTVIVGSRSN---.---RG.....GW..TTYKTATV.....AAMGE.GFIARD
 177 MFM..G..DGRSNTIITGSRNV---.---KD.....GS..TTFNSATV.....AAVGE.KFLARD
 178 MLV..G..DGKGKTVIVGSRSN---.---RG.....GW..NTYQSATV.....AAMGD.GFIARD
 179 FMF..G..DGATQTIITFDRSVGL-.---SP.....GT..TTSLSGTV.....QVESE.GFMAKW
 180 VFI..G..DGMGKTVITGSLNAG--.---MP.....GI..TTYNTATV.....GVVGD.GFMARD
 181 MIY..G..DGKGKTIISGSKNF---.---VD.....GT..PTYETATF.....AIQGK.GFIMKD
 182 TVI..G..DGPTKTKFTGSLNY---.---AD.....GI..NTYNTATF.....GVNGA.NFMAKD
 183 MFI..G..DGIGKTVIKANRSR---.---ID.....GW..STFQTPTV.....GVKGK.GYIAKD
 184 TLI..G..DGQDSTIITGNLSA---.---SN.....VR..RTFYTATFd11feASNGK.GFIGVD
 185 MIY..G..DGKDKTFVVGSRNF---.---MD.....GT..PTFETATF.....AVKGK.GFIAKD
 186 TVI..G..DGPTKTKFTGSLNY---.---AD.....GI..NTYKTATF.....GVNGA.NFMAKD
 187 MIT..G..DGIGKTIITGDKSK---.---GR.....GF..STYKSATF.....VAEGD.GFVGRD
 188 MLV..G..DGERKTIITSGRSV---.---QH.....GY..TTYNSATG.....GFGGQ.RFVAKD
 189 VIV..G..EGMGETVITGSRSM---.---AA.....GW..TTFRSATF.....AVSGA.GFIARD
 190 MLV..G..DGMDATIITGNLNV---.---VD.....GA..TTFNSATV.....AAVGD.GFIAQD
 191 TLV..G..DGRDLTVLSGDLNG---.---VD.....GI..KTFDSATL.....AVDES.GFMAQD
 192 TLI..G..DGQDLTIITSNLSA---.---SN.....VR..RTFNTATVg27feASNGN.GFIGVD
 193 MWV..G..DGIGKTVVKASRNV---.---VD.....GW..TTFQSATV.....AVVGD.GFIAKG
 194 VFL..G..DGMGKTVITGSISTG--.---IT.....RI..TTYNTATV.....GILGD.GFMASG
 195 VVQ..G..MGYSRTSIEWNNTT---.---AS.....SN..GTFSSFSV.....AVFGE.KFTAYN
 196 MLV..G..DGMDATIITGNLNV---.---ID.....GS..TTFKSATV.....AAVGD.GFIAQD
 197 MIV..G..DGMNATIITGSLNF---.---VD.....GT..TTFRSATL.....AAVGQ.GFILQD
 198 TLL..G..QPGAETVLTYHGTA---.----A.....QY..GTVESATL.....IVWAE.YFQAAH
 199 MLV..G..DGKDLTVITGSLNY---.---ID.....GT..GTFQTATV.....AAVGD.GFIGQD
 200 TLQ..G..QGFDITAIAWNDTA---.---YS.....AN..GTFYCATV.....QVFGS.QFVAKN
 201 TLS..G..TQASNTFLIW-------.---SD.....GE..DILESPTL.....TIFAS.DFVCRF
 202 VIQ..G..RGYQNTSIEWNDTA---.---KS.....AG..NTADSFSF.....VVFAA.NFTAYN
 203 FMR..G..NGKGKTVIESSQSS---.-----.....-V..DNVASATF.....KVEAN.HFVAFG
 204 TLM..G..QPNAMPVITYDGTA---.----A.....KY..GTVDSASL.....IILSD.YFMAVN
 205 YMQ..G..GGIEKTIIAY-------.---GD.....HQ..LTNTSATF.....TSYPS.NIIITG
 206 IVY..G..QTEDTTTYTSNLVNITHaIALAD.....VD..NDDETATL.....RNYAE.GSAIYN
 207 TLM..G..QPNAMPVITYDGTA---.----A.....KY..GTVDSASL.....IILSD.YFMAVN
 208 TLL..G..KPGAETNLTYAGTA---.----A.....KY..GTVESATL.....IVWAT.NFLAAN
 209 VLI..G..EGPTKTKITGNKSV---.---KD.....GP..STFHTTTV.....GVNGA.NFVAKN
 210 IIY..G..QTEDDTTYTGNLVNITHnIKLAD.....VA..NDDETATV.....RNHSP.NSSIYN
 211 ---..-..-----------------.-----.....--..--------.....-----.--MAQD
 212 TIY..G..ETTDTSGFASNTVTITQgKSQDD.....VS..GNDLTATL.....RAWTP.NLKVYN
 213 MIY..G..DGKDKTFVLGSRNF---.---MD.....GT..PTFETATF.....AVKGK.GFIAKD
 214 TLI..G..DGKYSTIIVGDDSV---.---AG.....GS..TMPGSATI.....TMTGD.GFIARD
 215 IIY..G..QTENTDSYADNLVTITH.AISYEda...GE..SDDLTATF.....RNKAV.GSQVYN
 216 MFI..G..DGRTRTIITGSRNV---.---VD.....GS..TTFKSATV.....-----.------
 217 TLY..SldANANNTVIVYNNANPTP.ASGAKt11naTV..GTVRSATA.....MVRAS.NFNARN
 218 ---..-..-----------------.-----.....--..--------.....AIDGN.WFMAQD
 219 MIV..G..DGMNSTVITGSLNV---.---VD.....GS..TTFRSATL.....AAVGQ.GFILQD
 220 TIY..G..ETKDTRSYSGNTVTITQrKSQND.....TP..SNDETATL.....RAHTP.NLKVYN
 221 TLY..G..TGEKPIDVKIGLSLDGG.MSPADw30sdSI..GVLCSAVF.....WSQNN.GLQLQN
 222 TLY..G..TGEKPIDVKIGLSLDGG.MSPADw30sdSI..GVLCSAVF.....WSQNN.GLQLQN
 223 TLF..G..AGDRPEQVVVSLALDSM.MSPADy30gaTI..NTTCSAVM.....WSQSN.DFQLKN
 224 TYL..G..RPWKEYSRTVVMES---.----Y.....LG..GLINPAGW.....AEWDG.DFALKT
 225 ---..-..-----------------.-----.....--..--------.....-----.------
 226 ---..-..--------TYNR-----.-----.....--..--------.....-----.---LTS
 227 TLI..A..DGQDSTIITFNLSS---.---SN.....SK..RTFNTATF.....G----.-KNLVD
 228 ---..-..-----------------.ILTAC.....GG..QTPNSARF.....QPVFP.GTVSRP
 229 ---..-..-----------------.-----.....--..--------.....-----.------
 230 ---..-..-----------------.-----.....--..--------.....-----.------
 231 MFM..G..DGRTRTIITGSRNV---.---VD.....GS..TTFHSATV.....AAVRE.KFLTRD
 232 ---..-..-----------------.-----.....--..--------.....-----.------
 233 MLV..G..DGKDATIITGSLNV---.---ID.....GS..TTFRSATV.....-----.------
 234 MFM..G..DGRTRTIITGSRNV---.---VD.....GS..TTFHSATV.....AA---.------
 235 ---..-..-----------------.-----.....--..--------.....-----.------
 236 ---..-..-----------------.-----.....--..--------.....-----.------
 237 ---..-..-----------------.-----.....--..--------.....-----.------
 238 ---..-..-----------------.-----.....--..--------.....-----.------
 239 IQA..N..NGDDVEINPANTAFTLV.---ND.....GT..GDGSGSTI.....RGF--.------
 240 TGM..G..NP----VVEANNSG---.-----.....--..-----SGF.....TLKSN.GNIIQG
 241 TLK..A..NGLVNIIASTSTGT---.-----.....--..------VI.....DVKAN.DTRIEG
 242 TFR..N..YENENVVISGESVA---.-----.....-N..AEYETPLI.....RIHDKhDIAISG
 243 ---..-..-----------------.-----.....--..--------.....-----.------
 244 TLK..A..NGLVNIIASTSTGT---.-----.....--..------VI.....DVKAN.DTRIEG
 245 TLE..A..NG-TVTVSAGNTTM---.-----.....--..-----PVF.....NVTAN.NTQVKG


           110       120       130       140       150            160  
            |         |         |         |         |              |  
   1 LTIRNDFDFPANQAKSDSDSSKIKDTQAVALYVTKSGDRAYFKDVSLVGYQDTLYV.....SGGR
   2 ICIQNTAG--------------PEKHQAVALRV--GGDMSVINRCPIDAYQDTLYA.....HSQR
   3 VQFQNTAG--------------AAKHQAVALRV--GADQSVINRCKIDAFQDTLYT.....HSLR
   4 VQFQNTAG--------------AAKHQAVALRV--GADQSVINRCKIDAFQDTLYT.....HSLR
   5 ICIQNTAG--------------PAKDQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSQR
   6 ICIQNTAG--------------PAKDQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSQR
   7 ITFQNTAG--------------PSKHQAVALRV--GADLSAFYNCDMLAYQDTLYV.....HSNR
   8 ITFQNTAG--------------PSKHQAVALRV--GADLSAFYNCDMLAYQDTLYV.....HSNR
   9 ICIQNTAG--------------PAKDQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSQR
  10 ICIQNTAG--------------PAKHQAVALRV--GADKSVINRCRIDAYQDTLYA.....HSQR
  11 ICIQNTAG--------------PAKHQAVALRV--GADKSVINRCRIDAYQDTLYA.....HSQR
  12 ICIQNTAG--------------PAKHQAVALRV--GADKSVINRCRIDAYQDTLYA.....HSQR
  13 ITFQNTAG--------------PSKHQAVALRV--GSDFSAFYQCDMFAYQDTLYV.....HSNR
  14 ITFQNTAG--------------ASKHQAVALRV--GSDLSAFYKCDILAYQDTLYV.....HSNR
  15 ICIQNTAG--------------PAKHQAVALRV--GADKSVINRCRIDAYQDTLYA.....HSQR
  16 ITFQNTAG--------------PSKHQAVALRV--GSDFSAFYNCDMLAYQDTLYV.....HSNR
  17 ITFQNTAG--------------ASKHQAVALCV--GSDLSAFYRCDMLAYQDTLYV.....HSNR
  18 IWFQNTAG--------------AAKHQAVALRV--GADQSVINRCRIDAFQDTLYA.....HSNR
  19 ITFENTAG--------------PEKHQAVALRS--DSDLSVFYRCNIRGYQDTLYT.....HTMR
  20 MTFRNTAG--------------PEKHQAVAMRS--SADLSIFYSCSFEAYQDTLYT.....HSLR
  21 ITFRNTAG--------------PEKHQAVALRS--GADFSIFYSCSFEAYQDTLYT.....HSLR
  22 LTIRNDFDFPANQAKSDSDSSKIKDTQAVALYVTKSGDRAYFKDVSLVGYQDTLYV.....SGGR
  23 LTIRNDFDFPANQAKSDSDSSKIKDTQAVALYVTKSGDRAYFKDVSLVGYQDTLYV.....SGGR
  24 MGFRNTAG--------------PEKHQAVAIRV--QADRAIFLNCRFEGYQDTLYA.....QTHR
  25 ITFRNTAG--------------ASNEQAVALRS--GSDLSVFYQCSFEAYQDTLYV.....HSNR
  26 I-FQNTAG--------------AAKHQAVALRV--GADQSVINRCRIDAFQDTLYA.....HSNR
  27 ICIQNTAG--------------PEKDQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSQR
  28 ITFQNTAG--------------PEKHQAVALRS--DSDLSVFFRCAMRGYQDTLYT.....HTMR
  29 IGIENTAG--------------PEGGQAVALRV--SADYAVFHSCQIDGHQDTLYV.....HSHR
  30 ITFQNTAG--------------PSKHQAVALRV--GSDFSAFYQCDMFAYQDTLYV.....HSNR
  31 IGFQNTAG--------------PEKHQAVALRV--GADQSVINRCKIDAFQDTLYA.....HSNR
  32 ITIRNTAG--------------PNNHQAVALRS--GSDLSVFYRCSFEGYQDTLYV.....HSQR
  33 IGFQNTAG--------------PEKHQAVALRV--GADQSVINRCKIDAFQDTLYA.....HSNR
  34 ITIRNTAG--------------PNNHQAVALRS--GSDLSVFYRCSFEGYQDTLYV.....HSQR
  35 LSFVNYAG--------------PEKHQAVALRS--SSDLSAYYRCSFESYQDTIYV.....HSHK
  36 MGFKNTAG--------------PMGHQAAAIRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
  37 VTFRNTAG--------------PEKHQAVALRN--NAEGSSFYRCSFEGYQDTLYV.....HSLR
  38 IGFKNTAG--------------PMGHQAVAIRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
  39 ITFENWAG--------------PAKHQAVALRI--GADHAVIYRCNIIGYQDTLYV.....HSNR
  40 IGFKNTAG--------------PMGHQAVAIRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
  41 IGFENTAG--------------AARHQAVALRV--SADFAVFFNCHMNGYQDTLYV.....HTHR
  42 MGFKNTAG--------------PMGHQAAAIRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
  43 MGFINTAG--------------PSKHQAVALMV--SADLTAFYRCTMNAYQDTLYV.....HAQR
  44 IGFENTAG--------------PEKEQAVALRV--SADKAIIYNCQIDGYQDTLYV.....HTYR
  45 IGFKNTAG--------------PLGHQAVALRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
  46 MGFRNTAG--------------PEGHQAVAIRV--QSDRSIFLNCRFEGYQDTLYA.....YTHR
  47 MGFHNTAG--------------AERHQAVALRV--QGDLAAFYNCRFDAFQDTLYV.....QPRR
  48 IGFQNTAG--------------PLGHQAVAFRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
  49 IGFENTAG--------------AIKHQAVAVRV--QSDESIFFNCRFDGYQDTLYT.....HSHR
  50 ITIRNTAG--------------PTKGQAVALRS--GGDLSVFYSCSFEAYQDTLYT.....HSLR
  51 ITFENTAG--------------PHKHQAVALRV--SSDLSLFYRCSFKGYQDTLFT.....HSLR
  52 IMITNTAG--------------PEKHQAVALRV--NADFVALYRCVIDGYQDTLYT.....HSFR
  53 ISFVNSAG--------------PAKAQAVAFRS--GSDHSAFYRCEFDGYQDTLYV.....HSAK
  54 MGFRNTAG--------------PEGHQAVAIRV--QSDRSVFLNCRFEGYQDTLYA.....YTHR
  55 ITFENTAG--------------PEKHQAVALRS--SSDFSVFYACSFKGYQDTLYL.....HSSR
  56 MTFVNNAG--------------PKSEQAVALRV--GADKSVVHRCSVEGYQDSLYT.....HSKR
  57 ITFRNTAG--------------PQNRQAVALRV--DSDQSAFYRCSVEGYQDTLYA.....HSLR
  58 ITFQNTAG--------------PEKHQAVAIRS--DTDLGVFYRCAMRGYQDTLYA.....HSMR
  59 IGFQNTAG--------------PLGNQAVAFRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
  60 ITFQNTAG--------------AAKHQAVALRV--GSDLSAFYRRDILAYQDSLYV.....HSNR
  61 IGFENTAG--------------TGKHQAVALRV--TADQAIFYNCQMDGFQDTLYV.....QSQR
  62 ITFVNSAG--------------PNSEQAVALRV--GSDRSVVYRCSIDGYQDSLYT.....LSKR
  63 IGIINTAG--------------AAKHQAVAFRS--GSDFSVYYQCSFDGFQDTLYP.....HSNR
  64 MCFRNTVG--------------PAKGPAVALRV--SGDMSVIYRCRVEGYQDALYP.....HIDR
  65 ITIRNTAG--------------PENHQAVALRS--NSDMSVFYRCSIEGYQDTLYV.....HSGR
  66 IGFENTAG--------------TSKFQAVALRV--TADQAIFHNCQMDGFQDTLFV.....ESQR
  67 IGFVNNAG--------------ASKHQAVALRS--GSDRSVFFRCSFDGFQDTLYA.....HSNR
  68 LTFQNTAG--------------PDAHQAVAFRS--DSDFSLIENCEFLGNQDTLYA.....HGLR
  69 MTFINTAG--------------PLRGQAVAVRS--SSDLSVFYRVGIHGFQDTLYI.....HSQR
  70 VQFQNTAG--------------AAKHQAVALRV--GAGQSVINRCKIDAFQDTLYT.....HSLR
  71 MTIRNTAG--------------PAAHQAVALRV--DSDRSAFFRIAVEGHQDTLYA.....HSLR
  72 ISIENTAG--------------PEKHQAVALRV--TADKAIFYNCQIDGYQATLFA.....ESQR
  73 LCIRNTAG--------------PEKRQAVALRI--STDMTIIYRCRIDAYQDTLYA.....YSGR
  74 VTFENSAG--------------PSKHQAVALRN--GADFSAFYQCSFVAYQDTLYV.....HSLR
  75 MCFRNTAG--------------PAKGPAVALRV--SGDMSVIYRCRVEGYQDALYP.....HSDR
  76 ISFKNNAPEPDPG---------EADAQAVALRI--EGDQAAFYGCGFYGAQDTLLD.....DKGR
  77 ISFKNTAPAPNPG---------AVDAQAVALKV--VGDKAAFYGCGFYGNQDTLLD.....QEGR
  78 LQFQNTAG--------------PQKHQAVALRV--GADQSVINRCKIDAFQDTLYT.....HTLR
  79 ICIQNTAG--------------PEKHQAVALRI--GGDMSVINRCRIDAYQDTLYA.....HSQR
  80 LTIQNKFG---------------TAGRAVALRV--AADKAAFYGCVITSYQDTLLD.....DNGN
  81 IWFQNTAG--------------PQKHQAVALRV--GADQSVINRCRVDAYQDTLYA.....HTNR
  82 LTIKNTAPMPKPG----------SQGQALAMRI--NADKAAFYSCRFHGFQDTLCD.....DKGN
  83 ISFMNVAPIPKPG---------DVGAQAVAIRI--AGDESAFVGCGFFGAQDTLHD.....DRGR
  84 LTIENTAG--------------PDAHQAVAFRS--DSDFSYIENCEFLGNQDTIYV.....HSLR
  85 LNIINTCG--------------QVCHQALAVSP--YGNGQGYYGCQFTGYQDTLLA.....QSGN
  86 ITFKNKYNI---------ASSSSPTKPAVAAMM--LGDKYAIIDSSFDGFQDTLYD.....DYGR
  87 LNIANTCG--------------QACHQALAVSA--YASEQGYYACQFTGYQDTLLA.....ETGY
  88 IVVKNTAPAPDGK---------TKGAQALSMRI--SGNFAAFYNCKFYGFQDTICD.....DTGN
  89 IVVKNTAPAPDGK---------TKGAQALSMRI--SGNFAAFYNCKFYGFQDTICD.....DTGN
  90 LNIINTSPMPKPG----------TQGQALAMRI--NGDKAAFYNCRFYGFQDTLCD.....DRGN
  91 INIVNTRG---------------EGSQALALSA--NADKQGYYGCQFKGYQDTILA.....QTGN
  92 INLVNTRG---------------QGSQALAVSA--WADKQGYYGCSFKGYQDTVLA.....QLGN
  93 IGFENTAG--------------PEKEQAVALRV--SADKAIIYNCQIDGYQDTLYV.....HTYR
  94 ISIRNDAPVGMAF---------TSENQSVAAFV--AADKVAFYHCAFYSLHNTLFD.....NKGR
  95 LNIANTCG--------------QACHQALALSA--WADQQGYYGCNFTGYQDTLLA.....QTGN
  96 IGFVNNAG--------------ASKHQAVALRS--GSDRSVFFRCSFDGFQDTLYA.....HSNR
  97 IGFQNTAG--------------PQGEQALALNI--ASDHSVLYRCSIAGYQDTLYA.....HALR
  98 IWFQNTAG--------------PAKHQAVALRV--SADQTVINRCRIDAYQDTLYT.....HTLR
  99 --------------------------------------------------------.....----
 100 LTFKNSYV---------EGTFADNNQSAVALAV--RGDKAILENVSVIGNQDTLYLga6ntMVIR
 101 LWIQNTAG--------------PAKGQAVALRV--SGDAVVIYRCRIDAYQDTLYA.....HSYR
 102 ICIQNTAG--------------PEKHQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSLR
 103 LTIENTLG----------DSVDAGNHPAVALRT--DGDQVQINNVNILGRQNTFFVt12tnRQPR
 104 LTIENTLG----------DSVDAGNHPAVALRT--DGDQVQINNVNILGRQNTFFVt12tnRQPR
 105 LTVVNALL----------DTVDSGTHQAVALRT--DGESGATGKCPPAQPSDTFFVn12tdHYSR
 106 --------------------------------M--LGDRYVVTDSSFVGLQDTLFD.....GKGR
 107 LTKANGMS--------------WDIKPAVAISV--YGDKSAFYNCDFLGLQDTVWD.....NLGR
 108 LYYGEFMN----------------------GKV--GADMSVINRCRIDAYQDTLYA.....HSQR
 109 MCFRNTTW--------------PVKGPVVTLRV--NGDMSIIYRCRVEEYQDALYP.....HKNR
 110 VLSAQEAG--------------RFTHQAVALRT--DGESGATGKCPPAQPSDTFFVn12tdHYSR
 111 ------------------------------------------------GRQDTFFVn12tdRYSR
 112 ------------------------------------------------GFQDTLYP.....HTNR
 113 ---------------------------------------------------DTLYA.....HSNR
 114 ITFXNT--------------------------------------------------.....----
 115 --------------------------------------------------------.....----
 116 --------------------------------------------------------.....----
 117 --------------------------------------------------------.....----
 118 --------------------------------------------------------.....----
 119 --------------------------------------------------------.....----
 120 ICIQNTAG--------------PEKHQAVALRV--GGDMSVINRCPIDAYQDTLYA.....HSQR
 121 VQFQNTAG--------------AAKHQAVALRV--GADQSVINRCKIDAFQDTLYT.....HSLR
 122 VQFQNTAG--------------AAKHQAVALRV--GADQSVINRCKIDAFQDTLYT.....HSLR
 123 ICIQNTAG--------------PAKHQAVALRV--GADKSVINRCRIDAYQDTLYA.....HSQR
 124 ICIQNTAG--------------PAKHQAVALRV--GADKSVINRCRIDAYQDTLYA.....HSQR
 125 ICIQNTAG--------------PAKDQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSQR
 126 ICIQNTAG--------------PAKDQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSQR
 127 ICIQNTAG--------------PAKHQAVALRV--GADKSVINRCRIDAYQDTLYA.....HSQR
 128 ITFQNTAG--------------PSKHQAVALRV--GADLSAFYNCDMLAYQDTLYV.....HSNR
 129 ITFQNTAG--------------PSKHQAVALRV--GADLSAFYNCDMLAYQDTLYV.....HSNR
 130 ICIQNTAG--------------PAKHQAVALRV--GADKSVINRCRIDAYQDTLYA.....HSQR
 131 IWFQNTAG--------------AAKHQAVALRV--GADQSVINRCRIDAFQDTLYA.....HSNR
 132 ICIQNTAG--------------PAKDQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSQR
 133 ITFQNTAG--------------ASKHQAVALRV--GSDLSAFYKCDILAYQDTLYV.....HSNR
 134 ITFQNTAG--------------PSKHQAVALRV--GSDFSAFYQCDMFAYQDTLYV.....HSNR
 135 ITFQNTAG--------------PSKHQAVALRV--GSDFSAFYNCDMLAYQDTLYV.....HSNR
 136 ITFQNTAG--------------ASKHQAVALCV--GSDLSAFYRCDMLAYQDTLYV.....HSNR
 137 IGFQNTAG--------------PEKHQAVALRV--GADQSVINRCKIDAFQDTLYA.....HSNR
 138 IGFQNTAG--------------PEKHQAVALRV--GADQSVINRCKIDAFQDTLYA.....HSNR
 139 ITFQNTAG--------------PSKHQAVALRV--GSDFSAFYQCDMFAYQDTLYV.....HSNR
 140 ICIQNTAG--------------PEKDQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSQR
 141 MTFRNTAG--------------PEKHQAVAMRS--SADLSIFYSCSFEAYQDTLYT.....HSLR
 142 ITFRNTAG--------------ASNEQAVALRS--GSDLSVFYQCSFEAYQDTLYV.....HSNR
 143 ITFENTAG--------------PEKHQAVALRS--DSDLSVFYRCNIRGYQDTLYT.....HTMR
 144 ITIRNTAG--------------PNNHQAVALRS--GSDLSVFYRCSFEGYQDTLYV.....HSQR
 145 ITFRNTAG--------------PEKHQAVALRS--GADFSIFYSCSFEAYQDTLYT.....HSLR
 146 ITIRNTAG--------------PNNHQAVALRS--GSDLSVFYRCSFEGYQDTLYV.....HSQR
 147 MGFRNTAG--------------PEKHQAVAIRV--QADRAIFLNCRFEGYQDTLYA.....QTHR
 148 I-FQNTAG--------------AAKHQAVALRV--GADQSVINRCRIDAFQDTLYA.....HSNR
 149 ITFQNTAG--------------PEKHQAVALRS--DSDLSVFFRCAMRGYQDTLYT.....HTMR
 150 ITFQNTAG--------------PEKHQAVAIRS--DTDLGVFYRCAMRGYQDTLYA.....HSMR
 151 LTIRNDFDFPANQAKSDSDSSKIKDTQAVALYVTKSGDRAYFKDVSLVGYQDTLYV.....SGGR
 152 LTIRNDFDFPANQAKSDSDSSKIKDTQAVALYVTKSGDRAYFKDVSLVGYQDTLYV.....SGGR
 153 ITFRNTAG--------------PQNRQAVALRV--DSDQSAFYRCSVEGYQDTLYA.....HSLR
 154 IGIENTAG--------------PEGGQAVALRV--SADYAVFHSCQIDGHQDTLYV.....HSHR
 155 ITIRNTAG--------------PTKGQAVALRS--GGDLSVFYSCSFEAYQDTLYT.....HSLR
 156 IGFENTAG--------------AIKHQAVAVRV--QSDESIFFNCRFDGYQDTLYT.....HSHR
 157 LSFVNYAG--------------PEKHQAVALRS--SSDLSAYYRCSFESYQDTIYV.....HSHK
 158 MGFKNTAG--------------PMGHQAAAIRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
 159 MGFHNTAG--------------AERHQAVALRV--QGDLAAFYNCRFDAFQDTLYV.....QPRR
 160 IMITNTAG--------------PEKHQAVALRV--NADFVALYRCVIDGYQDTLYT.....HSFR
 161 VTFRNTAG--------------PEKHQAVALRN--NAEGSSFYRCSFEGYQDTLYV.....HSLR
 162 IGFKNTAG--------------PMGHQAVAIRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
 163 IGFKNTAG--------------PMGHQAVAIRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
 164 MGFKNTAG--------------PMGHQAAAIRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
 165 ITFENWAG--------------PAKHQAVALRI--GADHAVIYRCNIIGYQDTLYV.....HSNR
 166 IGFKNTAG--------------PLGHQAVALRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
 167 IGFENTAG--------------PEKEQAVALRV--SADKAIIYNCQIDGYQDTLYV.....HTYR
 168 IGFENTAG--------------AARHQAVALRV--SADFAVFFNCHMNGYQDTLYV.....HTHR
 169 MGFINTAG--------------PSKHQAVALMV--SADLTAFYRCTMNAYQDTLYV.....HAQR
 170 IGFQNTAG--------------PLGHQAVAFRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
 171 ITFENTAG--------------PHKHQAVALRV--SSDLSLFYRCSFKGYQDTLFT.....HSLR
 172 MGFRNTAG--------------PEGHQAVAIRV--QSDRSVFLNCRFEGYQDTLYA.....YTHR
 173 ITFENTAG--------------PEKHQAVALRS--SSDFSVFYACSFKGYQDTLYL.....HSSR
 174 MGFRNTAG--------------PEGHQAVAIRV--QSDRSIFLNCRFEGYQDTLYA.....YTHR
 175 ISIENTAG--------------PEKHQAVALRV--TADKAIFYNCQIDGYQATLFA.....ESQR
 176 MTFVNNAG--------------PKSEQAVALRV--GADKSVVHRCSVEGYQDSLYT.....HSKR
 177 ITFQNTAG--------------AAKHQAVALRV--GSDLSAFYRRDILAYQDSLYV.....HSNR
 178 ITFVNSAG--------------PNSEQAVALRV--GSDRSVVYRCSIDGYQDSLYT.....LSKR
 179 IGFQNTAG--------------PLGNQAVAFRV--NGDRAVIFNCRFDGYQDTLYV.....NNGR
 180 LTFQNTAG--------------PDAHQAVAFRS--DSDFSLIENCEFLGNQDTLYA.....HGLR
 181 IGIINTAG--------------AAKHQAVAFRS--GSDFSVYYQCSFDGFQDTLYP.....HSNR
 182 IGFENTAG--------------TGKHQAVALRV--TADQAIFYNCQMDGFQDTLYV.....QSQR
 183 ISFVNSAG--------------PAKAQAVAFRS--GSDHSAFYRCEFDGYQDTLYV.....HSAK
 184 MCFRNTVG--------------PAKGPAVALRV--SGDMSVIYRCRVEGYQDALYP.....HIDR
 185 IGFVNNAG--------------ASKHQAVALRS--GSDRSVFFRCSFDGFQDTLYA.....HSNR
 186 IGFENTAG--------------TSKFQAVALRV--TADQAIFHNCQMDGFQDTLFV.....ESQR
 187 ITIRNTAG--------------PENHQAVALRS--NSDMSVFYRCSIEGYQDTLYV.....HSGR
 188 MTFINTAG--------------PLRGQAVAVRS--SSDLSVFYRVGIHGFQDTLYI.....HSQR
 189 MTIRNTAG--------------PAAHQAVALRV--DSDRSAFFRIAVEGHQDTLYA.....HSLR
 190 VQFQNTAG--------------AAKHQAVALRV--GAGQSVINRCKIDAFQDTLYT.....HSLR
 191 LCIRNTAG--------------PEKRQAVALRI--STDMTIIYRCRIDAYQDTLYA.....YSGR
 192 MCFRNTAG--------------PAKGPAVALRV--SGDMSVIYRCRVEGYQDALYP.....HSDR
 193 VTFENSAG--------------PSKHQAVALRN--GADFSAFYQCSFVAYQDTLYV.....HSLR
 194 LTIENTAG--------------PDAHQAVAFRS--DSDFSYIENCEFLGNQDTIYV.....HSLR
 195 ISFKNTAPAPNPG---------AVDAQAVALKV--VGDKAAFYGCGFYGNQDTLLD.....QEGR
 196 LQFQNTAG--------------PQKHQAVALRV--GADQSVINRCKIDAFQDTLYT.....HTLR
 197 ICIQNTAG--------------PEKHQAVALRI--GGDMSVINRCRIDAYQDTLYA.....HSQR
 198 LTIKNTAPMPKPG----------SQGQALAMRI--NADKAAFYSCRFHGFQDTLCD.....DKGN
 199 IWFQNTAG--------------PQKHQAVALRV--GADQSVINRCRVDAYQDTLYA.....HTNR
 200 ISFMNVAPIPKPG---------DVGAQAVAIRI--AGDESAFVGCGFFGAQDTLHD.....DRGR
 201 LTIQNKFG---------------TAGRAVALRV--AADKAAFYGCVITSYQDTLLD.....DNGN
 202 ISFKNNAPEPDPG---------EADAQAVALRI--EGDQAAFYGCGFYGAQDTLLD.....DKGR
 203 ISIRNDAPVGMAF---------TSENQSVAAFV--AADKVAFYHCAFYSLHNTLFD.....NKGR
 204 IVVKNTAPAPDGK---------TKGAQALSMRI--SGNFAAFYNCKFYGFQDTICD.....DTGN
 205 ITFKNKYN---------IASSSSPTKPAVAAMM--LGDKYAIIDSSFDGFQDTLYD.....DYGR
 206 LNIANTCG--------------QACHQALAVSA--YASEQGYYACQFTGYQDTLLA.....ETGY
 207 IVVKNTAPAPDGK---------TKGAQALSMRI--SGNFAAFYNCKFYGFQDTICD.....DTGN
 208 LNIINTSPMPKPG----------TQGQALAMRI--NGDKAAFYNCRFYGFQDTLCD.....DRGN
 209 IGFENTAG--------------PEKEQAVALRV--SADKAIIYNCQIDGYQDTLYV.....HTYR
 210 LNIINTCG--------------QVCHQALAVSP--YGNGQGYYGCQFTGYQDTLLA.....QSGN
 211 IWFQNTAG--------------PAKHQAVALRV--SADQTVINRCRIDAYQDTLYT.....HTLR
 212 INIVNTRG---------------EGSQALALSA--NADKQGYYGCQFKGYQDTILA.....QTGN
 213 IGFVNNAG--------------ASKHQAVALRS--GSDRSVFFRCSFDGFQDTLYA.....HSNR
 214 IGFQNTAG--------------PQGEQALALNI--ASDHSVLYRCSIAGYQDTLYA.....HALR
 215 LNIANTCG--------------QACHQALALSA--WADQQGYYGCNFTGYQDTLLA.....QTGN
 216 --------------------------------------------------------.....----
 217 LTFKNSYV---------EGTFADNNQSAVALAV--RGDKAILENVSVIGNQDTLYLga6ntMVIR
 218 LWIQNTAG--------------PAKGQAVALRV--SGDAVVIYRCRIDAYQDTLYA.....HSYR
 219 ICIQNTAG--------------PEKHQAVALRV--GADMSVINRCRIDAYQDTLYA.....HSLR
 220 INLVNTRG---------------QGSQALAVSA--WADKQGYYGCSFKGYQDTVLA.....QLGN
 221 LTIENTLG----------DSVDAGNHPAVALRT--DGDQVQINNVNILGRQNTFFVt12tnRQPR
 222 LTIENTLG----------DSVDAGNHPAVALRT--DGDQVQINNVNILGRQNTFFVt12tnRQPR
 223 LTVVNALL----------DTVDSGTHQAVALRT--DGESGATGKCPPAQPSDTFFVn12tdHYSR
 224 LYYGEFMN----------------------GKV--GADMSVINRCRIDAYQDTLYA.....HSQR
 225 -----------------------------------LGDRYVVTDSSFVGLQDTLFD.....GKGR
 226 LTKANGMS--------------WDIKPAVAISV--YGDKSAFYNCDFLGLQDTVWD.....NLGR
 227 MCFRNTTW--------------PVKGPVVTLRV--NGDMSIIYRCRVEEYQDALYP.....HKNR
 228 VLSAQEAG--------------RFTHQAVALRT--DGESGATGKCPPAQPSDTFFVn12tdHYSR
 229 ------------------------------------------------GRQDTFFVn12tdRYSR
 230 ------------------------------------------------GFQDTLYP.....HTNR
 231 ITFXNT--------------------------------------------------.....----
 232 ---------------------------------------------------DTLYA.....HSNR
 233 --------------------------------------------------------.....----
 234 --------------------------------------------------------.....----
 235 --------------------------------------------------------.....----
 236 --------------------------------------------------------.....----
 237 --------------------------------------------------------.....----
 238 --------------------------------------------------------.....----
 239 --IINSPP------------------HGVGVNI--SADNCKIENNRINGGKTGIAV.....SGCN
 240 FTIKNA--------------------------------------------------.....----
 241 FTIQGANGT-----------------------------------------------.....----
 242 LTIQD-------------LSVSSEEATAIGIYVSGSSSHIAIKDNHIRGIKTT---.....----
 243 --------------------------------------------------------.....----
 244 FTIQGANGT-----------------------------------------------.....----
 245 FTITGGKP------------------------------------------------.....----


           170       180        190        200       210         220   
            |         |          |          |         |           |   
   1 SFFSDCRISGTVDFIFGD.GTALFNNCDLVSRYRADVK.SGNVSGYLTAPST..NINQKYGLVIT
   2 QFYRDSYVSGTIDFIFGN.AAVVFQKCQLVARKP----.SKNQKNMVTAQGRt.DPNQATGTSIQ
   3 QFYRDCYITGTVDFIFGN.AAVVFQNSKIAARKP----.GSGQKNMVTAQGRe.DPNQNTGTSIQ
   4 QFYRDCYITGTVDFIFGN.AAVVFQNSKIAARKP----.GSGQKNMVTAQGRe.DPNQNTGTSIQ
   5 QFYRDSYVTGTVDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
   6 QFYRDSYVTGTVDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
   7 QFFVNCLIAGTVDFIFGN.AAAVLQNCDIHARKP----.NSGQKNMVTAQGRt.DPNQNTGIVIQ
   8 QFFVNCLIAGTVDFIFGN.AAAVLQNCDIHARKP----.NSGQKNMVTAQGRt.DPNQNTGIVIQ
   9 QFYRDSYVTGTVDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGTt.DPNQATGTSIQ
  10 QFYRDSYVTGTIDFIFGN.AAVVFQKCKLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
  11 QFYRDSYVTGTIDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
  12 QFYRDSYVTGTIDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
  13 QFFVKCHITGTVDFIFGN.AAAVLQDCDINARRP----.NSGQKNMVTAQGRs.DPNQNTGIVIQ
  14 QFFVQCLVAGTVDFIFGN.GAAVLQDCDIHARRP----.GSGQKNMVTAQGRt.DPNQNTGIVIQ
  15 QFYQSSYVTGTIDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
  16 QFFVKCLIAGTVDFIFGN.AAVVLQDCDIHARRP----.NSGQKNMVTAQGRt.DPNQNTGIVIQ
  17 QFFVQCLVAGTVDFIFGN.GAAVFQDCDIHARRP----.GSGQKNMVTAQGRt.DPNQNTGIVIQ
  18 QFYRDSVITGTIDFIFGN.AAVVFQKCNLVARKP----.MSNQKNMVTAQGRe.DPNQNTGTSIQ
  19 QFYRDCKISGTVDFIFGD.ATVVFQNCQILAKKG----.LPNQKNSITAQGRk.DPNEPTGISIQ
  20 QFYRECDIYGTVDFIFGN.AAVVFQDCNLYPRQP----.MQNQFNAITAQGRt.DPNQNTGISIH
  21 QFYRECDVYGTVDFIFGN.AAVVFQNCNLYPRKP----.MPNQFNAITAQGRs.DPNQNTGTSIQ
  22 SFFSDCRISGTVDFIFGD.GTALFNNCDLVSRYRADVK.SGNVSGYLTAPST..NINQKYGLVIT
  23 SFFSDCRISGTVDFIFGD.GTALFNNCDLVSRYRADVK.SGNVSGYLTAPST..NINQKYGLVIT
  24 QFYRSCVITGTVDFIFGD.ATSVFQNCLITVRKP----.LENQQNIVTAQGRi.DGHETTGIVLQ
  25 QFYRDCDVYGTVDFIFGN.AAAVLQNCNIFARRP----.-RSKTNTITAQGRs.DPNQNTGIIIH
  26 QFYRDSVITGTIDFIFGN.AAVVFQKCNLVARKP----.MSNQKNMVTAQGRe.DPNQNTGTS-Q
  27 QFYRDSYVTGTVDFIFGN.AAVVFQKCQIVARKP----.NKRQKNMVTAQGRt.DPNQATGTSIQ
  28 QFYRECTITGTVDFIFGD.GTVVFQNCQILAKRG----.LPNQKNTITAQGRk.DVNQPSGFSIQ
  29 QFYRDCTVSGTVDFIFGD.AKCILQNCKIVVRKP----.NKGQTCMVTAQGRs.NVRESTGLVLH
  30 QFFVKCHITGTVDFIFGN.AAAVLQDCDINARRP----.NSGQKNMVTAQGRs.DPNQNTGIVIQ
  31 QFYRDSFITGTVDFIFGN.AGVVFQKSKLVARKP----.MSNQKNMVTAQGRe.DPNQNTATSIQ
  32 QFYRECDIYGTVDFIFGN.AAVVLQNCNIFARKP----.-PNRTNTLTAQGRt.DPNQSTGIIIH
  33 QFYRDSFITGTVDFIFGN.AGVVFQKSKLVARKP----.MSNQKNMVTAQGRe.DPNQNTATSIQ
  34 QFYRECDIYGTVDFIFGN.AAVVLQNCNIFARXP----.-PNRTNTLTAQGRt.DPNQNTGIIIH
  35 QFYRECDIYGTVDFIFGD.ASVVFQNCSLYARRP----.NPNQKIIYTAQGRe.NSREPTGISII
  36 QFYRNCVVSGTVDFIFGK.SATVIQNTLIVVRKG----.SKGQYNTVTADGNelGLGMKIGIVLQ
  37 QFYRECDIYGTVDFIFGN.AAAIFQNCNIYARKP----.MAKQKNAITAHGRl.DPNQNTGISII
  38 QFYRNIVVSGTVDFIFGK.SATVIQNSLIVVRKG----.NKGQFNTVTADGNekGLAMKIGIVLQ
  39 QFFRECDIYGTVDFIFGN.AAVVLQNCSIYARKP----.MDFQKNTITAQNRk.DPNQNTGISIH
  40 QFYRNIVVSGTVDFIFGK.SATVIQNSLIVVRKG----.NKGQFNTVTADGNekGLAMKIGIVLQ
  41 QFYRNCRVSGTIDFVFGD.AKAVFQNCEFVIRRP----.MEHQQCIVTAQGRk.DRRETTGIVIH
  42 QFYRNCVVSGTVDFIFGK.SATVIQNTLIVVRKG----.SKGQYNTVTADGNelGLGMKIGIVLQ
  43 QFYRECTIIGTVDFIFGN.SASVLQSCRILPRRP----.MKGQQNTITAQGRt.DPNMNTGISIH
  44 QFYRDCTITGTVDFIFGN.GEAVLQNCKVIVRKP----.AQNQSCMVTAQGRt.EPIQKGAIVLQ
  45 QFYRNIVVSGTVDFIFGK.SATVIQNSLILVRKG----.SPGQSNYVTADGNekGAAMKIGIVLH
  46 QYYRSCVIVGTIDFIFGD.AAAIFQNCNIFIRKG----.LPGQKNTVTAQGRv.DKFQTTGFVVH
  47 QFFRNCVVSGTIDFIFGN.SAAVFQNCLIITRRP----.MDNQQNSVTAHGPt.DPNMKSGLVIQ
  48 QFYRNIVVSGTVDFIFGK.SATVIQNSLILCRKG----.SPGQTNHVTADGNekGKAVKIGIVLH
  49 QFFRDCTISGTIDFLFGD.AAAVFQNCTLLVRKP----.LPNQACPITAHGRk.DPRESTGFVFQ
  50 QFYRECDVYGTVDFIFGN.AAVVLQNCNLYPRQP----.RKGQSNEVTAQGRt.DPNQNTGTAIH
  51 QFYRDCHIYGTIDFIFGD.AAAVFQNCDIFVRRP----.MDHQGNMITAQGRd.DPHTNSEFEAV
  52 QFYRECDIYGTIDYIFGN.AAVVFQGCNIVSKLP----.MPGQFTVITAQSRd.TQDEDTGISMQ
  53 QFYRECDIYGTIDFIFGN.AAVVFQNSSLYARKP----.NPGHKIAFTAQSRn.QSDQPTGISIL
  54 QYYRSCVIIGTVDFIFGD.AAAIFQNCDIFIRKG----.LPGQKNTVTAQGRv.DKFQTTGFVIH
  55 QFLRNCNIYGTVDFIFGD.ATAILQNCNIYARKP----.MSGQKNTITAQSRk.EPDETTGFVIQ
  56 QFYRETDITGTVDFIFGN.SAVVFQSCNIAARKP----.LPGQRNFVTAQGRs.NPGQNTGIAIQ
  57 QFYRDCEIYGTIDFIFGN.GAAVLQNCKIYTRVP----.LPLQKVTITAQGRk.SPNQNTGFVIQ
  58 QFFRECIITGTVDFIFGD.ATAVFQSCQIKAKQG----.LPNQKNSITAQGRk.DPNEPTGFTIQ
  59 QFYRNIVVSGTVDFINGK.SATVIQNSLILCRKG----.SPGQTNHVTADGKqkGKAVKIGIVLH
  60 QYFVQCLIAGTVDFIFGN.AAAVLQNCDIHARRP----.GSGQKNMVTAQGRt.DPNQNTGVVIQ
  61 QFYRDCSISGTIDFVFGE.RFGVFQNCKLVCRLP----.AKGQQCLVTAGGRe.KQNSASALVFQ
  62 QFYRETDITGTVDFIFGN.SAVVFQSCNLVSRKG----.-SSDQNYVTAQGRs.DPNQNTGISIH
  63 QFYRDCDVTGTIDFIFGS.AAVVFQGCKIMPRQP----.LSNQFNTITAQGKk.DPNQSSGMSIQ
  64 QFYRECFITGTVDFICGN.AAAVFQFCQIVARQP----.NMGQSNFITAQSRe.TKDDKSGFSIQ
  65 QFFRECDIYGTVDFIFGN.AAAVLQNCRIFARNP----.-PNGVNTITAQSRf.NPNQTTGIVIH
  66 QFYRDCAISGTIDFVFGD.AFGVFQNCKLICRVP----.AKGQKCLVTAGGRd.KQNSASALVFL
  67 QFYRDCDITGTIDFIFGN.AAVVFQSCKIMPRQP----.LPNQFNTITAQGKk.DPNQNTGIIIQ
  68 QFYKNCRIQGNVDFIFGN.SAAVFQDCEILIAPRQINP.EKGEKNAVTAQGRi.DPSQSTGFVFL
  69 QFFRECYISGTIDFIFGN.AAVVFQNCMILVRRP----.LHGQANIITAQGRg.DPFQNTGITIH
  70 QFYRDCYITGTVDFIFGN.AAVVFQNSKIAARKP----.GSGQKNMVTAQGRe.DPNQNTGTSIQ
  71 QFYRDCRVSGTVDFIFGN.GIAVIQRTTISTLPP---A.AGQNAGSVTAQGRr.DPNQNTGFALH
  72 QFYRDCSISGTIDMIYGD.AFAVFQNCKLIVRKP----.LEEQQCFVAADGRt.KSDSSSGFVFQ
  73 QFYRDCYITGTVDFIFGR.AAAVFQYCQIEARKP----.GIGQTNILTAQSRe.EDTATSGFSFQ
  74 QFYRECDVYGTVDFIFGN.AAAVLQNCNLYARKP----.NKNQRNLFTAQGRe.DPNQSTGISII
  75 QFYRECFITGTVDFICGN.AVAVFQFCQIVARQP----.KMGQSNVITAQSRa.FKDIYSGFTIQ
  76 HFFKECFIQGSIDFIFGN.GRSLYQDCTINSIAK--GN.TSGVTGSITAQGRq.SEDEQSGFSFV
  77 HFFKGCFIEGSIDFIFGN.GRSLYEDCTLHSIAK----.-ENTIGCITANGKd.TLKDRTGFVFV
  78 QFYRDCYITGTVDFIFGN.AAVVFQNSKLAARKP----.MSGQKNMVTAQGRe.DPNQVTGTSIQ
  79 QFYRDSYVSGTIDFIFGN.AAVVFQKCQLVARKP----.SKYQKNMVTAQGRt.DPNQATGTSIQ
  80 HYFKNCYIEGATDFICGS.ASSLYERCHLHSLSP----.---NNGSITAQMRt.SATEKSGFTFL
  81 QFYRDSFITGTVDFIFGN.AAVVFQKCYLVARKP----.MSNQKNMVTAQGRe.DPNQSTGTSIQ
  82 HFFKDCYIEGTYDFIFGR.GASLYLNTQLHA-------.VGDGLRVITAQGRq.SATEQNGYTFV
  83 HYFKDCYIQGSIDFIFGN.AKSLYQDCRIISMANQLSPgSKAVNGAVTANGRs.SKDENSGFSFV
  84 QLFKSCRIEGNVDFIFGN.AAAIFQDCTILVRPRQVKP.EKGETNAIAAHGRt.DPAQTTGFAFL
  85 QVYAHNLIEGAVDFIFGQhARAWFQDCDIRVLKG----.--PSSGYITANGRs.SETDTSYYVIH
  86 HYYKRCVISGGIDFIFGG.AQSIFEGCTLKLRVG-IYP.PNEVYGTITAQGRd.SPTDKGGFVFK
  87 QVYAGTYIEGAVDFIFGQhARAWFHECDIRVLEG----.--PSSASITANGRs.SESDDSYYVIH
  88 HFFKDCYVEGTFDFIFGS.GTSMYLGTQLHV-------.VGDGIRVIAAHAGk.SAEEKSGYSFV
  89 HFFKDCYVEGTFDFIFGS.GTSMYLGTQLHV-------.VGDGIRVIAAHAGk.SAEEKSGYSFV
  90 HFFKNCYIEGTYDFIFGR.GASLYLTTQLHA-------.VGDGLRVIAAHNRq.STTEQNGYSFV
  91 QVYAKSYIEGATDFIFGQkATAWFDGVDIRV-------.LAASLGYITANGRd.SDSNPSYYVIN
  92 QVYAKSYIEGATDFIFGQqARAWFDGCDIGV-------.LGAQVGWITASGRa.ADSNPSYYVFN
  93 QFYRDCTITGTVDFIFGN.GEAVLQNCKVIVRKP----.AQNQSCMVTAQGRt.EPIQKGAIVLQ
  94 HYYHECYIQGSIDFIFGR.ATSIFNNCEIFVISD---K.RVKPYGSITAHHRe.SAEEKTGYVFI
  95 QLYINSYIEGAVDFIFGQhARAWFQNVDIRVVEG----.--PTSASITANGRs.SETDTSYYVIN
  96 QFYRDCDITGTIDFIFGN.AAVVFQSCKIMPRQP----.LPNQFNTITAQGKk.DPNQNTGIIIQ
  97 QFYRECDIYGTVDFIFGN.AAAVFQNCYLVLRLP----.RKKGYNVILANGRs.DPGQNTGFSVH
  98 QFYRDSYITGTVDFIFGN.SAVVFQNCDIVARNP----.GAGQKNMLTAQGRe.DQNQNTAISIQ
  99 ----------------GQ.TAAVLQNCDIHARKP----.NSGQKNMVTAQGRa.DPNQNTGIVIQ
 100 AYFKNSFIQGDTDFIFGA.GTAVFHGCTIQYTAA--RL.GARATSYVFAPST..APDNPHGFLAI
 101 QFYRDCFITGTVDFIFGH.ASAIFQNCRIEARKP----.MEGQSNVITAQQS..DKPGTSGFSIQ
 102 QFYRDCYVTGTVDFIFGN.AAVVLQKCQLVPRKP----.GKNQKNMVTAQGRt.DPNQATGTSIQ
 103 TLVTNSYIEGDVDIVSGR.GAVVFDNTEFRVVNS----.RTQQEAYVFAPAT..LSNIYYGFLAV
 104 TLVTNSYIEGDVDIVSGR.GAVVFDNTEFRVVNS----.RTQQEAYVFAPAT..LSNIYYGFLAV
 105 AYIKDSYIEGDVDYVFGR.ATAVFDRVRFHTVSS----.RGSKEAYVFAPDS..IPSVKYGFLVI
 106 HYYKRCIISGGIDFIFGY.GQSLFKECTLNMTLG-IYA.PDNPYGTITAHQRp.SPSDEGGFVFS
 107 HHFKNCYIEGAIDFIFGS.GQSVYE-------------.-------------..-----------
 108 QFYRDDYVTGTVDFIFGG.AAVVKNKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
 109 QCYREYFLMDTVDFICGN.AAAVFQFCQIV--------.-------------..-----------
 110 AYIKDSYIEGDVDYVFGR.ATAVFDRVRFHTVSS----.RGSKEAYVFAPDS..IPSVKYGFLVI
 111 AYIKDSYIEGDVDYVFGR.ATAVFDRVHFHTVSS----.RGAKDIHVFAPDS..MPWAQYGFLAV
 112 QFYRECRISGTVDFIFGD.ATVVFQNCQILVKKG----.LPNQKNTITAQGRk.DPAQPTGFSIQ
 113 QFYRECDITGTIDFIFGN.AAVVFQACKIQPRQP----.MSNQFNTITAQGKk.DPNQNTGISIQ
 114 ------------------.-------------------.-------------..-----------
 115 ------------------.-------------------.-------------..-----------
 116 ---------GTXDFIFGN.AAVVFQDCNLYPRQP----.MQNQFNAITAQGRt.DPNQNTGISIY
 117 ---------GTXDFIFGN.SAVVFQNCDIVARNP----.GAGQKNMLTAQGRe.DQNQNTAISIQ
 118 ------------------.-------------------.-------------..-----------
 119 ---------GTXDFIFGA.GTVVFQGCSIRPRQP----.LPNQFNTITAEGTq.EANQNTGISIH
 120 QFYRDSYVSGTIDFIFGN.AAVVFQKCQLVARKP----.SKNQKNMVTAQGRt.DPNQATGTSIQ
 121 QFYRDCYITGTVDFIFGN.AAVVFQNSKIAARKP----.GSGQKNMVTAQGRe.DPNQNTGTSIQ
 122 QFYRDCYITGTVDFIFGN.AAVVFQNSKIAARKP----.GSGQKNMVTAQGRe.DPNQNTGTSIQ
 123 QFYRDSYVTGTIDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
 124 QFYRDSYVTGTIDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
 125 QFYRDSYVTGTVDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
 126 QFYRDSYVTGTVDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
 127 QFYRDSYVTGTIDFIFGN.AAVVFQKCKLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
 128 QFFVNCLIAGTVDFIFGN.AAAVLQNCDIHARKP----.NSGQKNMVTAQGRt.DPNQNTGIVIQ
 129 QFFVNCLIAGTVDFIFGN.AAAVLQNCDIHARKP----.NSGQKNMVTAQGRt.DPNQNTGIVIQ
 130 QFYQSSYVTGTIDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
 131 QFYRDSVITGTIDFIFGN.AAVVFQKCNLVARKP----.MSNQKNMVTAQGRe.DPNQNTGTSIQ
 132 QFYRDSYVTGTVDFIFGN.AAVVFQKCQLVARKP----.GKYQQNMVTAQGTt.DPNQATGTSIQ
 133 QFFVQCLVAGTVDFIFGN.GAAVLQDCDIHARRP----.GSGQKNMVTAQGRt.DPNQNTGIVIQ
 134 QFFVKCHITGTVDFIFGN.AAAVLQDCDINARRP----.NSGQKNMVTAQGRs.DPNQNTGIVIQ
 135 QFFVKCLIAGTVDFIFGN.AAVVLQDCDIHARRP----.NSGQKNMVTAQGRt.DPNQNTGIVIQ
 136 QFFVQCLVAGTVDFIFGN.GAAVFQDCDIHARRP----.GSGQKNMVTAQGRt.DPNQNTGIVIQ
 137 QFYRDSFITGTVDFIFGN.AGVVFQKSKLVARKP----.MSNQKNMVTAQGRe.DPNQNTATSIQ
 138 QFYRDSFITGTVDFIFGN.AGVVFQKSKLVARKP----.MSNQKNMVTAQGRe.DPNQNTATSIQ
 139 QFFVKCHITGTVDFIFGN.AAAVLQDCDINARRP----.NSGQKNMVTAQGRs.DPNQNTGIVIQ
 140 QFYRDSYVTGTVDFIFGN.AAVVFQKCQIVARKP----.NKRQKNMVTAQGRt.DPNQATGTSIQ
 141 QFYRECDIYGTVDFIFGN.AAVVFQDCNLYPRQP----.MQNQFNAITAQGRt.DPNQNTGISIH
 142 QFYRDCDVYGTVDFIFGN.AAAVLQNCNIFARRP----.-RSKTNTITAQGRs.DPNQNTGIIIH
 143 QFYRDCKISGTVDFIFGD.ATVVFQNCQILAKKG----.LPNQKNSITAQGRk.DPNEPTGISIQ
 144 QFYRECDIYGTVDFIFGN.AAVVLQNCNIFARKP----.-PNRTNTLTAQGRt.DPNQSTGIIIH
 145 QFYRECDVYGTVDFIFGN.AAVVFQNCNLYPRKP----.MPNQFNAITAQGRs.DPNQNTGTSIQ
 146 QFYRECDIYGTVDFIFGN.AAVVLQNCNIFARXP----.-PNRTNTLTAQGRt.DPNQNTGIIIH
 147 QFYRSCVITGTVDFIFGD.ATSVFQNCLITVRKP----.LENQQNIVTAQGRi.DGHETTGIVLQ
 148 QFYRDSVITGTIDFIFGN.AAVVFQKCNLVARKP----.MSNQKNMVTAQGRe.DPNQNTGTS-Q
 149 QFYRECTITGTVDFIFGD.GTVVFQNCQILAKRG----.LPNQKNTITAQGRk.DVNQPSGFSIQ
 150 QFFRECIITGTVDFIFGD.ATAVFQSCQIKAKQG----.LPNQKNSITAQGRk.DPNEPTGFTIQ
 151 SFFSDCRISGTVDFIFGD.GTALFNNCDLVSRYRADVK.SGNVSGYLTAPST..NINQKYGLVIT
 152 SFFSDCRISGTVDFIFGD.GTALFNNCDLVSRYRADVK.SGNVSGYLTAPST..NINQKYGLVIT
 153 QFYRDCEIYGTIDFIFGN.GAAVLQNCKIYTRVP----.LPLQKVTITAQGRk.SPNQNTGFVIQ
 154 QFYRDCTVSGTVDFIFGD.AKCILQNCKIVVRKP----.NKGQTCMVTAQGRs.NVRESTGLVLH
 155 QFYRECDVYGTVDFIFGN.AAVVLQNCNLYPRQP----.RKGQSNEVTAQGRt.DPNQNTGTAIH
 156 QFFRDCTISGTIDFLFGD.AAAVFQNCTLLVRKP----.LPNQACPITAHGRk.DPRESTGFVFQ
 157 QFYRECDIYGTVDFIFGD.ASVVFQNCSLYARRP----.NPNQKIIYTAQGRe.NSREPTGISII
 158 QFYRNCVVSGTVDFIFGK.SATVIQNTLIVVRKG----.SKGQYNTVTADGNelGLGMKIGIVLQ
 159 QFFRNCVVSGTIDFIFGN.SAAVFQNCLIITRRP----.MDNQQNSVTAHGPt.DPNMKSGLVIQ
 160 QFYRECDIYGTIDYIFGN.AAVVFQGCNIVSKLP----.MPGQFTVITAQSRd.TQDEDTGISMQ
 161 QFYRECDIYGTVDFIFGN.AAAIFQNCNIYARKP----.MAKQKNAITAHGRl.DPNQNTGISII
 162 QFYRNIVVSGTVDFIFGK.SATVIQNSLIVVRKG----.NKGQFNTVTADGNekGLAMKIGIVLQ
 163 QFYRNIVVSGTVDFIFGK.SATVIQNSLIVVRKG----.NKGQFNTVTADGNekGLAMKIGIVLQ
 164 QFYRNCVVSGTVDFIFGK.SATVIQNTLIVVRKG----.SKGQYNTVTADGNelGLGMKIGIVLQ
 165 QFFRECDIYGTVDFIFGN.AAVVLQNCSIYARKP----.MDFQKNTITAQNRk.DPNQNTGISIH
 166 QFYRNIVVSGTVDFIFGK.SATVIQNSLILVRKG----.SPGQSNYVTADGNekGAAMKIGIVLH
 167 QFYRDCTITGTVDFIFGN.GEAVLQNCKVIVRKP----.AQNQSCMVTAQGRt.EPIQKGAIVLQ
 168 QFYRNCRVSGTIDFVFGD.AKAVFQNCEFVIRRP----.MEHQQCIVTAQGRk.DRRETTGIVIH
 169 QFYRECTIIGTVDFIFGN.SASVLQSCRILPRRP----.MKGQQNTITAQGRt.DPNMNTGISIH
 170 QFYRNIVVSGTVDFIFGK.SATVIQNSLILCRKG----.SPGQTNHVTADGNekGKAVKIGIVLH
 171 QFYRDCHIYGTIDFIFGD.AAAVFQNCDIFVRRP----.MDHQGNMITAQGRd.DPHTNSEFEAV
 172 QYYRSCVIIGTVDFIFGD.AAAIFQNCDIFIRKG----.LPGQKNTVTAQGRv.DKFQTTGFVIH
 173 QFLRNCNIYGTVDFIFGD.ATAILQNCNIYARKP----.MSGQKNTITAQSRk.EPDETTGFVIQ
 174 QYYRSCVIVGTIDFIFGD.AAAIFQNCNIFIRKG----.LPGQKNTVTAQGRv.DKFQTTGFVVH
 175 QFYRDCSISGTIDMIYGD.AFAVFQNCKLIVRKP----.LEEQQCFVAADGRt.KSDSSSGFVFQ
 176 QFYRETDITGTVDFIFGN.SAVVFQSCNIAARKP----.LPGQRNFVTAQGRs.NPGQNTGIAIQ
 177 QYFVQCLIAGTVDFIFGN.AAAVLQNCDIHARRP----.GSGQKNMVTAQGRt.DPNQNTGVVIQ
 178 QFYRETDITGTVDFIFGN.SAVVFQSCNLVSRKG----.-SSDQNYVTAQGRs.DPNQNTGISIH
 179 QFYRNIVVSGTVDFINGK.SATVIQNSLILCRKG----.SPGQTNHVTADGKqkGKAVKIGIVLH
 180 QFYKNCRIQGNVDFIFGN.SAAVFQDCEILIAPRQINP.EKGEKNAVTAQGRi.DPSQSTGFVFL
 181 QFYRDCDVTGTIDFIFGS.AAVVFQGCKIMPRQP----.LSNQFNTITAQGKk.DPNQSSGMSIQ
 182 QFYRDCSISGTIDFVFGE.RFGVFQNCKLVCRLP----.AKGQQCLVTAGGRe.KQNSASALVFQ
 183 QFYRECDIYGTIDFIFGN.AAVVFQNSSLYARKP----.NPGHKIAFTAQSRn.QSDQPTGISIL
 184 QFYRECFITGTVDFICGN.AAAVFQFCQIVARQP----.NMGQSNFITAQSRe.TKDDKSGFSIQ
 185 QFYRDCDITGTIDFIFGN.AAVVFQSCKIMPRQP----.LPNQFNTITAQGKk.DPNQNTGIIIQ
 186 QFYRDCAISGTIDFVFGD.AFGVFQNCKLICRVP----.AKGQKCLVTAGGRd.KQNSASALVFL
 187 QFFRECDIYGTVDFIFGN.AAAVLQNCRIFARNP----.-PNGVNTITAQSRf.NPNQTTGIVIH
 188 QFFRECYISGTIDFIFGN.AAVVFQNCMILVRRP----.LHGQANIITAQGRg.DPFQNTGITIH
 189 QFYRDCRVSGTVDFIFGN.GIAVIQRTTISTLPP---A.AGQNAGSVTAQGRr.DPNQNTGFALH
 190 QFYRDCYITGTVDFIFGN.AAVVFQNSKIAARKP----.GSGQKNMVTAQGRe.DPNQNTGTSIQ
 191 QFYRDCYITGTVDFIFGR.AAAVFQYCQIEARKP----.GIGQTNILTAQSRe.EDTATSGFSFQ
 192 QFYRECFITGTVDFICGN.AVAVFQFCQIVARQP----.KMGQSNVITAQSRa.FKDIYSGFTIQ
 193 QFYRECDVYGTVDFIFGN.AAAVLQNCNLYARKP----.NKNQRNLFTAQGRe.DPNQSTGISII
 194 QLFKSCRIEGNVDFIFGN.AAAIFQDCTILVRPRQVKP.EKGETNAIAAHGRt.DPAQTTGFAFL
 195 HFFKGCFIEGSIDFIFGN.GRSLYEDCTLHSIAK----.-ENTIGCITANGKd.TLKDRTGFVFV
 196 QFYRDCYITGTVDFIFGN.AAVVFQNSKLAARKP----.MSGQKNMVTAQGRe.DPNQVTGTSIQ
 197 QFYRDSYVSGTIDFIFGN.AAVVFQKCQLVARKP----.SKYQKNMVTAQGRt.DPNQATGTSIQ
 198 HFFKDCYIEGTYDFIFGR.GASLYLNTQLHAVGD----.---GLRVITAQGRq.SATEQNGYTFV
 199 QFYRDSFITGTVDFIFGN.AAVVFQKCYLVARKP----.MSNQKNMVTAQGRe.DPNQSTGTSIQ
 200 HYFKDCYIQGSIDFIFGN.AKSLYQDCRIISMANQLSPgSKAVNGAVTANGRs.SKDENSGFSFV
 201 HYFKNCYIEGATDFICGS.ASSLYERCHLHSLSP----.---NNGSITAQMRt.SATEKSGFTFL
 202 HFFKECFIQGSIDFIFGN.GRSLYQDCTINSIAK--GN.TSGVTGSITAQGRq.SEDEQSGFSFV
 203 HYYHECYIQGSIDFIFGR.ATSIFNNCEIFVISD---K.RVKPYGSITAHHRe.SAEEKTGYVFI
 204 HFFKDCYVEGTFDFIFGS.GTSMYLGTQLHVVGD----.---GIRVIAAHAGk.SAEEKSGYSFV
 205 HYYKRCVISGGIDFIFGG.AQSIFEGCTLKLRVG-IYP.PNEVYGTITAQGRd.SPTDKGGFVFK
 206 QVYAGTYIEGAVDFIFGQhARAWFHECDIRVLEG----.--PSSASITANGRs.SESDDSYYVIH
 207 HFFKDCYVEGTFDFIFGS.GTSMYLGTQLHVVGD----.---GIRVIAAHAGk.SAEEKSGYSFV
 208 HFFKNCYIEGTYDFIFGR.GASLYLTTQLHAVGD----.---GLRVIAAHNRq.STTEQNGYSFV
 209 QFYRDCTITGTVDFIFGN.GEAVLQNCKVIVRKP----.AQNQSCMVTAQGRt.EPIQKGAIVLQ
 210 QVYAHNLIEGAVDFIFGQhARAWFQDCDIRVLKG----.--PSSGYITANGRs.SETDTSYYVIH
 211 QFYRDSYITGTVDFIFGN.SAVVFQNCDIVARNP----.GAGQKNMLTAQGRe.DQNQNTAISIQ
 212 QVYAKSYIEGATDFIFGQkATAWFDGVDIRVLAA----.---SLGYITANGRd.SDSNPSYYVIN
 213 QFYRDCDITGTIDFIFGN.AAVVFQSCKIMPRQP----.LPNQFNTITAQGKk.DPNQNTGIIIQ
 214 QFYRECDIYGTVDFIFGN.AAAVFQNCYLVLRLP----.RKKGYNVILANGRs.DPGQNTGFSVH
 215 QLYINSYIEGAVDFIFGQhARAWFQNVDIRVVEG----.--PTSASITANGRs.SETDTSYYVIN
 216 ----------------GQ.TAAVLQNCDIHARKP----.NSGQKNMVTAQGRa.DPNQNTGIVIQ
 217 AYFKNSFIQGDTDFIFGA.GTAVFHGCTIQYTAARL--.GARATSYVFAPST..APDNPHGFLAI
 218 QFYRDCFITGTVDFIFGH.ASAIFQNCRIEARKP----.MEGQSNVITAQQS..DKPGTSGFSIQ
 219 QFYRDCYVTGTVDFIFGN.AAVVLQKCQLVPRKP----.GKNQKNMVTAQGRt.DPNQATGTSIQ
 220 QVYAKSYIEGATDFIFGQqARAWFDGCDIGV-------.LGAQVGWITASGRa.ADSNPSYYVFN
 221 TLVTNSYIEGDVDIVSGR.GAVVFDNTEFRVVNS----.RTQQEAYVFAPAT..LSNIYYGFLAV
 222 TLVTNSYIEGDVDIVSGR.GAVVFDNTEFRVVNS----.RTQQEAYVFAPAT..LSNIYYGFLAV
 223 AYIKDSYIEGDVDYVFGR.ATAVFDRVRFHTVSS----.RGSKEAYVFAPDS..IPSVKYGFLVI
 224 QFYRDDYVTGTVDFIFGG.AAVVKNKCQLVARKP----.GKYQQNMVTAQGRt.DPNQATGTSIQ
 225 HYYKRCIISGGIDFIFGY.GQSLFKECTLNMTLG-IYA.PDNPYGTITAHQRp.SPSDEGGFVFS
 226 HHFKNCYIEGAIDFIFGS.GQSVYE-------------.-------------..-----------
 227 QCYREYFLMDTVDFICGN.AAAVFQFCQIV--------.-------------..-----------
 228 AYIKDSYIEGDVDYVFGR.ATAVFDRVRFHTVSS----.RGSKEAYVFAPDS..IPSVKYGFLVI
 229 AYIKDSYIEGDVDYVFGR.ATAVFDRVHFHTVSS----.RGAKDIHVFAPDS..MPWAQYGFLAV
 230 QFYRECRISGTVDFIFGD.ATVVFQNCQILVKKG----.LPNQKNTITAQGRk.DPAQPTGFSIQ
 231 ------------------.-------------------.-------------..-----------
 232 QFYRECDITGTIDFIFGN.AAVVFQACKIQPRQP----.MSNQFNTITAQGKk.DPNQNTGISIQ
 233 ------------------.-------------------.-------------..-----------
 234 ------------------.-------------------.-------------..-----------
 235 ---------GTXDFIFGN.AAVVFQDCNLYPRQP----.MQNQFNAITAQGRt.DPNQNTGISIY
 236 ---------GTXDFIFGN.SAVVFQNCDIVARNP----.GAGQKNMLTAQGRe.DQNQNTAISIQ
 237 ---------GTXDFIFGA.GTVVFQGCSIRPRQP----.LPNQFNTITAEGTq.EANQNTGISIH
 238 ----------TIDFIFGN.AVVVLQECNIISRKP----.LHGQATVITAQSRd.DPLEPTGIVIQ
 239 TTILNNVISG--------.-------------------.-------------..-----------
 240 ------------------.-------------------.-------------..-----------
 241 ------------------.-------------------.-------------..-----------
 242 ------------------.-------------------.-------------..-----------
 243 ------------------.-------------------.-------------..-----------
 244 ------------------.-------------------.-------------..-----------
 245 ------------------.-------------------.-------------..-----------


           230            240       250       260       270         280
            |              |         |         |         |           |
   1 NSRVIR.ESDSVPAK.....SYGLGRPWHPTTTFSDGRYADPNAIGQTVFLNTSMDNHIY..GWD
   2 FCDIIA.SPDLEPVVkef..KTYLGRPWKEYSR--------------TVVMQSYLGGLIDpaGWA
   3 NCDIIP.SSDLAPVKgsv..KTYLGRPWKAYSR--------------TVFMQSNIGDHIDpeGWS
   4 NCDIIP.SSDLAPVKgsv..KTYLGRPWKAYSR--------------TVFMQSNIGDHIDpeGWS
   5 FCNIIA.SSDLEPVLkef..PTYLGRPWKEYSR--------------TVVMESYLGGLINpaGWA
   6 FCDIIA.SSDLEPLLkef..PTYLGRPWKEYSR--------------TVVMESYLGGLINpaGWA
   7 KSRIGA.TSDLKPVQgsf..PTYLGRPWKEYSR--------------TVIMQSSITDLIHpaGWH
   8 KSRIGA.TSDLKPVQgsf..PTYLGRPWKEYSR--------------TVIMQSSITDLIHpaGWH
   9 FCNIIA.SSDLEPVLkef..PTYLGRPWKEYSR--------------TVVMESYLGGLINpaGWA
  10 FCNIIA.SSDLEPVLkef..PTYLGRPWKKYSR--------------TVVMESYLGGLINpaGWA
  11 FCDIIA.SPDLKPVVkef..PTYLGRPWKKYSR--------------TVVMESYLGGLIDpsGWA
  12 FCDIIA.SPDLKPVVkef..PTYLGRPWKKYSR--------------TVVMESYLGGLIDpsGWA
  13 NCRIGG.TSDLLAVKgtf..PTYLGRPWKEYSR--------------TVIMQSDISDVIRpeGWH
  14 KCRIGA.TSDLRPVQksf..PTYLGRPWKEYSR--------------TVIMQSSITDVIQpaGWH
  15 FCDIIA.SPDLKPVVkef..PTYLGRPWKKYSR--------------TVVMESSLGGLIDpsGWA
  16 KCRIGA.TSDLQSVKgsf..PTYLGRPWKEYSQ--------------TVIMQSAISDVIRpeGWS
  17 KCRIGA.TSDLRPVQksf..PTYLGRPWKEYSR--------------TVIMQSSITDVIQpaGWH
  18 QCNLTP.SSDLKAVVgsi..KTYLGRPWKKYSR--------------TVIMQSSIDSHIDptGWA
  19 FCNITA.DSDLEAASvnst.PTYLGRPWKLYSR--------------TVIMQSFLSNVIRpeGWL
  20 NCTIKP.ADDLVSSNytv..KTYLGRPWKEYSR--------------TVFMQSYIDEVVEpvGWR
  21 NCTIKP.ADDLVSSNytv..KTYLGRPWKEYSR--------------TVYMQSYIDGFVEpvGWR
  22 NSRVIR.ESDSVPAK.....SYGLGRPWHPTTTFSDGRYADPNAIGQTVFLNTSMDNHIY..GWD
  23 NSRVIR.ESDSVPAK.....SYGLGRPWHPTTTFSDGRYADPNAIGQTVFLNTSMDNHIY..GWD
  24 SCRIEP.DKDLVPVKnki..RSYLGRPWKEFSR--------------TVIMDSTIGDFIHpgGWL
  25 NSRVTA.ASDLRPVLgst..KTYLGRPWRQYSR--------------TVFMKTSLDSLIDprGWL
  26 QCNLTP.SSDLKAVVgsi..KTYLGRPWKKYSR--------------TVIMQSSIDSHIDptGWA
  27 FCDIIA.SPDLEPVMney..KTYLGRPWKKHSR--------------TVVMQSYLDGHIDpsGWF
  28 FSNISA.DADLVPYLntt..RTYLGRPWKLYSR--------------TVFIRNNMSDVVRpeGWL
  29 GCHITG.DPAYIPMKsvn..KAYLGRPWKEFSR--------------TIIMKTTIDDVIDpaGWL
  30 NCRIGG.TSDLLAVKgtf..PTYLGRPWKEYSR--------------TVIMQSDISDVIRpeGWH
  31 QCNVIP.SSDLKPVQgsi..KTYLGRPWKKYSR--------------TVVLQSVVDSHIDpaGWA
  32 NCRVTA.ASDLKPVQssv..KTFLGRPWKQYSR--------------TVYIKTFLDSLINpaGWM
  33 QCNVIP.SSDLKPVQgsi..KTYLGRPWKKYSR--------------TVVLQSVVDSHIDpaGWA
  34 NCRVTA.ASDLKPVQssv..KTFLGRPWKQYSR--------------TVXIKTFLDSLINpaGWM
  35 SSRILA.APDLIPVQanf..KAYLGRPWQLYSR--------------TVIMKSFIDDLVDpaGWL
  36 NCRIVP.DRKLTPERltv..ATYLGRPWKKFST--------------TVIMSTEMGDLIRpeGWK
  37 NCTIKA.APDLAAEPksa..MTFLGRPWKPYSR--------------TVFMQSYISDIVQpvGWL
  38 NCRIVP.DKKLAAERliv..ESYLGRPWKKFST--------------TVIINSEIGDVIRpeGWK
  39 ASRVLA.ASDLQATNgst..QTYLGRPWKLFSR--------------TVYMMSYIGGHVHtrGWL
  40 NCRIVP.DKKLAAERliv..ESYLGRPWKKFST--------------TVIINSEIGDVIRpeGWK
  41 NSRITG.DASYLPVKakn..RAFLGRPWKEFSR--------------TIIMNTEIDDVIDpeGWL
  42 NCRIVP.DRKLTPERltv..ATYLGRPWKKFST--------------TVIMSTEMGDLIRpeGWK
  43 RCNISP.LGDLTDV-.....MTFLGRPWKNFST--------------TVIMDSYLHGFIDrkGWL
  44 NCEIKP.DTDYFSLSpps..KTYLGRPWKEYSR--------------TIIMQSYIDKFIEpeGWA
  45 NCRIIP.DKELEADKlti..KSYLGRPWKKFAT--------------TVIIGTEIGDLIKpeGWT
  46 NCKIAA.NEDLKPVKeey..KSYLGRPWKNYSR--------------TIIMESKIENVIDpvGWL
  47 NCRLVP.DQKLFPDRfki..PSYLGRPWKEFSR--------------LVIMESTIADFVKpeGYM
  48 NCRIMA.DKELEADRltv..KSYLGRPWKPFAT--------------TAVIGTEIGDLIQptGWN
  49 GCTIAG.EPDYLAVKets..KAYLGRPWKEYSR--------------TIIMNTFIPDFVQpqGWQ
  50 GCTIRP.ADDLATSNytv..KTYLGRPWKEYSR--------------TVVMQTYIDGFLEpsGWN
  51 KGRF--.--------.....KSYLGRPWKKYSR--------------TVFLKTDIDELIDprGWR
  52 NCSILA.SEDLFNSSnkv..KSYLGRPWREFSR--------------TVVMESYIDEFIDgsGWS
  53 NCRILA.APDLIPVKenf..KAYLGRPWRKYSR--------------TVIIKSFIDDLIHpaGWL
  54 NCTVAP.NEDLKPVKaqf..KSYLGRPWKPHSR--------------TVVMESTIEDVIDpvGWL
  55 SSTVAT.AS------.....ETYLGRPWRSHSR--------------TVFMKCNLGALVSpaGWL
  56 NCRITA.ES------.....MTYLGRPWKEYSR--------------TVVMQSFIGGSIHpsGWS
  57 NSYVLA.TQ------.....PTYLGRPWKLYSR--------------TVYMNTYMSQLVQprGWL
  58 FSNIAA.DTDLLLNLntt..ATYLGRPWKLYSR--------------TVFMQNYMSDAINpvGWL
  59 NCRIMA.DKELEADRltv..KSYLGRPWKPFAT--------------TAVIGTEIGDLIQptGWN
  60 NCRIGA.TSDLRPVQksf..PTYLGRPWKEYSR--------------TVIMQSSITDVINsaGWH
  61 SSHFTG.EPALTSVTpk...VSYLGRPWKQYSK--------------VVIMDSTIDAIFVpeGYM
  62 NCRITG.ST------.....KTYLGRPWKQYSR--------------TVVMQSFIDGSIHpsGWS
  63 RCTISA.NGNVIA--.....PTYLGRPWKEFST--------------TVIMETVIGAVVRpsGWM
  64 NCNITA.SSDLDTATv....KTYLGRPWRIFST--------------VAVLQSFIGDLVDpaGWT
  65 NSVVKG.APGVQLGGv....KTYLGRPWRSYAR--------------TVVIGTYLDTLIEpnGWI
  66 SSHFTG.EPALTSVTpk...LSYLGRPWKLYSK--------------VVIMDSTIDAMFApeGYM
  67 KSTITP.FGNNLTA-.....PTYLGRPWKDFST--------------TVIMQSDIGALLNpvGWM
  68 NCLING.TEEYMKLFka7vhKNFLGRPWKDYSR--------------TVFIGCNLEALITpdGWL
  69 SSRIIA.ASDLKPVIray..KTYLGRPWQAYSR--------------VTIMKTYIDNSISplGWS
  70 NCDIIP.SSDLAPVKgsv..KTYLGRPWKAYSR--------------TVFMQSNIGDHIDpeGWS
  71 ACIVEA.KY------.....PTYLGRPWKPFSR--------------VVVMESYLGAGVQprGWL
  72 SCHFTG.EPEVAKIDpk...IAYLGRPWKSYSK--------------VVIMDSNIDDIFDpeGYM
  73 KCNISA.SSDLTPIKgtv..KTFLGRPWRAFSR--------------VVFMESFIDDVIDr.---
  74 NCKVAA.AADLIPVKsef..RNYLGRPWKMYSR--------------TVFLNSLMEDLIEpaGWL
  75 KCNITA.SSDLDTTTv....KTYLGRPWRIFST--------------VAVMQSFIGDLVDpaGWT
  76 NCKIDG.SG------.....EILLGRAWGAYAT--------------VVFSNTYMSGIITpeGWN
  77 NCKITG.SA------.....RVWLGRAWRPYAR--------------VIFSKTYMSRVVSldGWN
  78 NCDIIP.SSDLAPVKgsv..KTYLGRPW--------------------------------..---
  79 FCDIIA.SPDLEPVVnef..KTYLGRPW--------------------------------..---
  80 GCKLTG.SG------.....STFLGRPWGAYSR--------------VVFAYSFFSNVVApqGWN
  81 QCNITP.SLDLKPVAgsi..KTYLGRPW--------------------------------..---
  82 HCKVTG.TGT-----.....GIYLGRSWMSHPK--------------VVYAFTEMTSVVNpsGWR
  83 NCTIGG.TG------.....HVWLGRAWRPYSR--------------VVFVSTTMTDVIApeGWN
  84 GCLING.TDDYMKLYhs7khKNYLGRPWKMYSR--------------TVYINCTMESLIApeGWL
  85 KSSVAAaDGNDVPSG.....TYYLGRPWSQYAR--------------VLYQETSMTDVINsaGWS
  86 DCTVMG.SG------.....KALLGRAWKSYSR--------------VIFYRSMFSDNILpiGWD
  87 KSTVAAaDGNDVSSG.....TYYLGRPWSQYAR--------------VCFQKTSMTDVINhlGWT
  88 HCKVTG.TGG-----.....GIYLGRAWMSHPK--------------VVYAYTEMTSVVNptGWQ
  89 HCKVTG.TGG-----.....GIYLGRAWMSHPK--------------VVYAYTEMTSVVNptGWQ
  90 HCKVTG.VGT-----.....GIYLGRAWMSHPK--------------VVYSYTEMSSVVNpsGWQ
  91 KSKVSAaSGNTVKAG.....AFYLGRPWRNYAR--------------VVFQNTAPSNVVNakGWT
  92 KSKVSPaVGATVSSG.....VYYLGRPWGNYAR--------------VVFQHTDLSNVINpqGWA
  93 NCEIKP.DTDYFSLSpps..KTYLGRPW--------------------------------..---
  94 RGKVYG.ID------.....EVYLGRAKGPYSR--------------VIFAKTYLSKTVVpdGWT
  95 KSTVAAkEGDDVAEG.....TYYLGRPWSEYAR--------------VVFQQTSMTNVINslGWT
  96 KSTITP.FGNNLTA-.....PTYLGRPW--------------------------------..---
  97 NCRIVP.SSEFSPVKhky..ESYLGRPW--------------------------------..---
  98 KCKITA.SSDLAPVKgsv..KTFLGRPWKLYSR--------------TVIMQSFIDNHIDpaGWF
  99 KSRIGA.TSDLKPVQgsf..PTYLGRPWKEYSR--------------TVIMQSSITDVIHpaGWH
 100 NSTFNA.TGNASNN-.....STHLGRAWDQGVSGTSAYINGSSPNGQVVIRDSSLGAHIR..LAD
 101 NCSITA.SSDLVPVKrmv..KTFLGRPWGDFST--------------VVFMESYLDDMIDpmGWT
 102 FCNIIA.SPDLEPVKney..KTYLGRPW--------------------------------..---
 103 NSRFNA.FGD----G.....VAQLGRSLDVDAN----------TNGQVVIRDSAINEGFN..TAK
 104 NSRFNA.FGD----G.....VAQLGRSLDVDAN----------TNGQVVIRDSAINEGFN..TAK
 105 NSQLTG.DNGYRGAQ.....KAKLGRAWDQGAK-QTGYLPGKTANGQLVIRDSTIDSSYD..LAN
 106 DCTVTG.VG------.....KTLLGRAWGSNAR--------------VIFDRSRLSDVVLpiGWD
 107 ------.----VWST.....SVYLGRAYGPFSR--------------VIFIQTDLSSVVHpeGWY
 108 FCNIIA.SGDLERPVmivgd--------GMYATTITGSL--NVVEGSTTFRSATLAAVGQ..GTL
 109 ------.--------.....----------------------------------------..---
 110 NSQLTG.DNGYRGAQ.....KAKLGRAWD-------------------------------..---
 111 SCRFTG.DEGFSGGR.....KAKLGRAWDQGAR-QTGYQPNKTANGQLVIRDSTIDASYD..REQ
 112 FSNISA.DSDLLASVnst..LSHLGRPW--------------------------------..---
 113 KCSISA.LN------.....----------------------------------------..---
 114 ------.--------.....----------------------------------------..---
 115 ------.--------.....----------------------------------------..---
 116 NCTIKP.ADDLVSSNytv..KTYXGRPWKEY-----------------------------..---
 117 KCKITA.SSDLAPVKgsv..KTYXGRPWKEY-----------------------------..---
 118 ------.--------.....----------------------------------------..---
 119 QCTISP.NGNVTA--.....TTYXGRPWKEY-----------------------------..---
 120 FCDIIA.SPDLEPVVkef..KTYLGRPWKEYSR--------------TVVMQSYLGGLIDpaGWA
 121 NCDIIP.SSDLAPVKgsv..KTYLGRPWKAYSR--------------TVFMQSNIGDHIDpeGWS
 122 NCDIIP.SSDLAPVKgsv..KTYLGRPWKAYSR--------------TVFMQSNIGDHIDpeGWS
 123 FCDIIA.SPDLKPVVkef..PTYLGRPWKKYSR--------------TVVMESYLGGLIDpsGWA
 124 FCDIIA.SPDLKPVVkef..PTYLGRPWKKYSR--------------TVVMESYLGGLIDpsGWA
 125 FCNIIA.SSDLEPVLkef..PTYLGRPWKEYSR--------------TVVMESYLGGLINpaGWA
 126 FCDIIA.SSDLEPLLkef..PTYLGRPWKEYSR--------------TVVMESYLGGLINpaGWA
 127 FCNIIA.SSDLEPVLkef..PTYLGRPWKKYSR--------------TVVMESYLGGLINpaGWA
 128 KSRIGA.TSDLKPVQgsf..PTYLGRPWKEYSR--------------TVIMQSSITDLIHpaGWH
 129 KSRIGA.TSDLKPVQgsf..PTYLGRPWKEYSR--------------TVIMQSSITDLIHpaGWH
 130 FCDIIA.SPDLKPVVkef..PTYLGRPWKKYSR--------------TVVMESSLGGLIDpsGWA
 131 QCNLTP.SSDLKAVVgsi..KTYLGRPWKKYSR--------------TVIMQSSIDSHIDptGWA
 132 FCNIIA.SSDLEPVLkef..PTYLGRPWKEYSR--------------TVVMESYLGGLINpaGWA
 133 KCRIGA.TSDLRPVQksf..PTYLGRPWKEYSR--------------TVIMQSSITDVIQpaGWH
 134 NCRIGG.TSDLLAVKgtf..PTYLGRPWKEYSR--------------TVIMQSDISDVIRpeGWH
 135 KCRIGA.TSDLQSVKgsf..PTYLGRPWKEYSQ--------------TVIMQSAISDVIRpeGWS
 136 KCRIGA.TSDLRPVQksf..PTYLGRPWKEYSR--------------TVIMQSSITDVIQpaGWH
 137 QCNVIP.SSDLKPVQgsi..KTYLGRPWKKYSR--------------TVVLQSVVDSHIDpaGWA
 138 QCNVIP.SSDLKPVQgsi..KTYLGRPWKKYSR--------------TVVLQSVVDSHIDpaGWA
 139 NCRIGG.TSDLLAVKgtf..PTYLGRPWKEYSR--------------TVIMQSDISDVIRpeGWH
 140 FCDIIA.SPDLEPVMney..KTYLGRPWKKHSR--------------TVVMQSYLDGHIDpsGWF
 141 NCTIKP.ADDLVSSNytv..KTYLGRPWKEYSR--------------TVFMQSYIDEVVEpvGWR
 142 NSRVTA.ASDLRPVLgst..KTYLGRPWRQYSR--------------TVFMKTSLDSLIDprGWL
 143 FCNITA.DSDLEAASvnst.PTYLGRPWKLYSR--------------TVIMQSFLSNVIRpeGWL
 144 NCRVTA.ASDLKPVQssv..KTFLGRPWKQYSR--------------TVYIKTFLDSLINpaGWM
 145 NCTIKP.ADDLVSSNytv..KTYLGRPWKEYSR--------------TVYMQSYIDGFVEpvGWR
 146 NCRVTA.ASDLKPVQssv..KTFLGRPWKQYSR--------------TVXIKTFLDSLINpaGWM
 147 SCRIEP.DKDLVPVKnki..RSYLGRPWKEFSR--------------TVIMDSTIGDFIHpgGWL
 148 QCNLTP.SSDLKAVVgsi..KTYLGRPWKKYSR--------------TVIMQSSIDSHIDptGWA
 149 FSNISA.DADLVPYLntt..RTYLGRPWKLYSR--------------TVFIRNNMSDVVRpeGWL
 150 FSNIAA.DTDLLLNLntt..ATYLGRPWKLYSR--------------TVFMQNYMSDAINpvGWL
 151 NSRVIR.ESDSVPAK.....SYGLGRPWHPTTTFSDGRYADPNAIGQTVFLNTSMDNHIY..GWD
 152 NSRVIR.ESDSVPAK.....SYGLGRPWHPTTTFSDGRYADPNAIGQTVFLNTSMDNHIY..GWD
 153 NSYVLA.TQ------.....PTYLGRPWKLYSR--------------TVYMNTYMSQLVQprGWL
 154 GCHITG.DPAYIPMKsvn..KAYLGRPWKEFSR--------------TIIMKTTIDDVIDpaGWL
 155 GCTIRP.ADDLATSNytv..KTYLGRPWKEYSR--------------TVVMQTYIDGFLEpsGWN
 156 GCTIAG.EPDYLAVKets..KAYLGRPWKEYSR--------------TIIMNTFIPDFVQpqGWQ
 157 SSRILA.APDLIPVQanf..KAYLGRPWQLYSR--------------TVIMKSFIDDLVDpaGWL
 158 NCRIVP.DRKLTPERltv..ATYLGRPWKKFST--------------TVIMSTEMGDLIRpeGWK
 159 NCRLVP.DQKLFPDRfki..PSYLGRPWKEFSR--------------LVIMESTIADFVKpeGYM
 160 NCSILA.SEDLFNSSnkv..KSYLGRPWREFSR--------------TVVMESYIDEFIDgsGWS
 161 NCTIKA.APDLAAEPksa..MTFLGRPWKPYSR--------------TVFMQSYISDIVQpvGWL
 162 NCRIVP.DKKLAAERliv..ESYLGRPWKKFST--------------TVIINSEIGDVIRpeGWK
 163 NCRIVP.DKKLAAERliv..ESYLGRPWKKFST--------------TVIINSEIGDVIRpeGWK
 164 NCRIVP.DRKLTPERltv..ATYLGRPWKKFST--------------TVIMSTEMGDLIRpeGWK
 165 ASRVLA.ASDLQATNgst..QTYLGRPWKLFSR--------------TVYMMSYIGGHVHtrGWL
 166 NCRIIP.DKELEADKlti..KSYLGRPWKKFAT--------------TVIIGTEIGDLIKpeGWT
 167 NCEIKP.DTDYFSLSpps..KTYLGRPWKEYSR--------------TIIMQSYIDKFIEpeGWA
 168 NSRITG.DASYLPVKakn..RAFLGRPWKEFSR--------------TIIMNTEIDDVIDpeGWL
 169 RCNISP.LGDLTDV-.....MTFLGRPWKNFST--------------TVIMDSYLHGFIDrkGWL
 170 NCRIMA.DKELEADRltv..KSYLGRPWKPFAT--------------TAVIGTEIGDLIQptGWN
 171 KGRF--.--------.....KSYLGRPWKKYSR--------------TVFLKTDIDELIDprGWR
 172 NCTVAP.NEDLKPVKaqf..KSYLGRPWKPHSR--------------TVVMESTIEDVIDpvGWL
 173 SSTVAT.AS------.....ETYLGRPWRSHSR--------------TVFMKCNLGALVSpaGWL
 174 NCKIAA.NEDLKPVKeey..KSYLGRPWKNYSR--------------TIIMESKIENVIDpvGWL
 175 SCHFTG.EPEVAKIDpk...IAYLGRPWKSYSK--------------VVIMDSNIDDIFDpeGYM
 176 NCRITA.ES------.....MTYLGRPWKEYSR--------------TVVMQSFIGGSIHpsGWS
 177 NCRIGA.TSDLRPVQksf..PTYLGRPWKEYSR--------------TVIMQSSITDVINsaGWH
 178 NCRITG.ST------.....KTYLGRPWKQYSR--------------TVVMQSFIDGSIHpsGWS
 179 NCRIMA.DKELEADRltv..KSYLGRPWKPFAT--------------TAVIGTEIGDLIQptGWN
 180 NCLING.TEEYMKLFka7vhKNFLGRPWKDYSR--------------TVFIGCNLEALITpdGWL
 181 RCTISA.NGNVIA--.....PTYLGRPWKEFST--------------TVIMETVIGAVVRpsGWM
 182 SSHFTG.EPALTSVTpk...VSYLGRPWKQYSK--------------VVIMDSTIDAIFVpeGYM
 183 NCRILA.APDLIPVKenf..KAYLGRPWRKYSR--------------TVIIKSFIDDLIHpaGWL
 184 NCNITA.SSDLDTATv....KTYLGRPWRIFST--------------VAVLQSFIGDLVDpaGWT
 185 KSTITP.FGNNLTA-.....PTYLGRPWKDFST--------------TVIMQSDIGALLNpvGWM
 186 SSHFTG.EPALTSVTpk...LSYLGRPWKLYSK--------------VVIMDSTIDAMFApeGYM
 187 NSVVKG.APGVQLGGv....KTYLGRPWRSYAR--------------TVVIGTYLDTLIEpnGWI
 188 SSRIIA.ASDLKPVIray..KTYLGRPWQAYSR--------------VTIMKTYIDNSISplGWS
 189 ACIVEA.KY------.....PTYLGRPWKPFSR--------------VVVMESYLGAGVQprGWL
 190 NCDIIP.SSDLAPVKgsv..KTYLGRPWKAYSR--------------TVFMQSNIGDHIDpeGWS
 191 KCNISA.SSDLTPIKgtv..KTFLGRPWRAFSR--------------VVFMESFIDDVIDr.---
 192 KCNITA.SSDLDTTTv....KTYLGRPWRIFST--------------VAVMQSFIGDLVDpaGWT
 193 NCKVAA.AADLIPVKsef..RNYLGRPWKMYSR--------------TVFLNSLMEDLIEpaGWL
 194 GCLING.TDDYMKLYhs7khKNYLGRPWKMYSR--------------TVYINCTMESLIApeGWL
 195 NCKITG.SA------.....RVWLGRAWRPYAR--------------VIFSKTYMSRVVSldGWN
 196 NCDIIP.SSDLAPVKgsv..KTYLGRPW--------------------------------..---
 197 FCDIIA.SPDLEPVVnef..KTYLGRPW--------------------------------..---
 198 HCKVTG.TGT-----.....GIYLGRSWMSHPK--------------VVYAFTEMTSVVNpsGWR
 199 QCNITP.SLDLKPVAgsi..KTYLGRPW--------------------------------..---
 200 NCTIGG.TG------.....HVWLGRAWRPYSR--------------VVFVSTTMTDVIApeGWN
 201 GCKLTG.SG------.....STFLGRPWGAYSR--------------VVFAYSFFSNVVApqGWN
 202 NCKIDG.SG------.....EILLGRAWGAYAT--------------VVFSNTYMSGIITpeGWN
 203 RGKVYG.ID------.....EVYLGRAKGPYSR--------------VIFAKTYLSKTVVpdGWT
 204 HCKVTG.TGG-----.....GIYLGRAWMSHPK--------------VVYAYTEMTSVVNptGWQ
 205 DCTVMG.SG------.....KALLGRAWKSYSR--------------VIFYRSMFSDNILpiGWD
 206 KSTVAAaDGNDVSSG.....TYYLGRPWSQYAR--------------VCFQKTSMTDVINhlGWT
 207 HCKVTG.TGG-----.....GIYLGRAWMSHPK--------------VVYAYTEMTSVVNptGWQ
 208 HCKVTG.VGT-----.....GIYLGRAWMSHPK--------------VVYSYTEMSSVVNpsGWQ
 209 NCEIKP.DTDYFSLSpps..KTYLGRPW--------------------------------..---
 210 KSSVAAaDGNDVPSG.....TYYLGRPWSQYAR--------------VLYQETSMTDVINsaGWS
 211 KCKITA.SSDLAPVKgsv..KTFLGRPWKLYSR--------------TVIMQSFIDNHIDpaGWF
 212 KSKVSAaSGNTVKAG.....AFYLGRPWRNYAR--------------VVFQNTAPSNVVNakGWT
 213 KSTITP.FGNNLTA-.....PTYLGRPW--------------------------------..---
 214 NCRIVP.SSEFSPVKhky..ESYLGRPW--------------------------------..---
 215 KSTVAAkEGDDVAEG.....TYYLGRPWSEYAR--------------VVFQQTSMTNVINslGWT
 216 KSRIGA.TSDLKPVQgsf..PTYLGRPWKEYSR--------------TVIMQSSITDVIHpaGWH
 217 NSTFNA.TGNASNN-.....STHLGRAWDQGVSGTSAYINGSSPNGQVVIRDSSLGAHIR..LAD
 218 NCSITA.SSDLVPVKrmv..KTFLGRPWGDFST--------------VVFMESYLDDMIDpmGWT
 219 FCNIIA.SPDLEPVKney..KTYLGRPW--------------------------------..---
 220 KSKVSPaVGATVSSG.....VYYLGRPWGNYAR--------------VVFQHTDLSNVINpqGWA
 221 NSRFNA.FGDG----.....VAQLGRSLDVDAN----------TNGQVVIRDSAINEGFN..TAK
 222 NSRFNA.FGDG----.....VAQLGRSLDVDAN----------TNGQVVIRDSAINEGFN..TAK
 223 NSQLTG.DNGYRGAQ.....KAKLGRAWDQGAK-QTGYLPGKTANGQLVIRDSTIDSSYD..LAN
 224 FCNIIA.SGDLERPVmivgd--------GMYATTITGSLN--VVEGSTTFRSATLAAVGQ..GTL
 225 DCTVTG.VG------.....KTLLGRAWGSNAR--------------VIFDRSRLSDVVLpiGWD
 226 ------.----VWST.....SVYLGRAYGPFSR--------------VIFIQTDLSSVVHpeGWY
 227 ------.--------.....----------------------------------------..---
 228 NSQLTG.DNGYRGAQ.....KAKLGRAWD-------------------------------..---
 229 SCRFTG.DEGFSGGR.....KAKLGRAWDQGAR-QTGYQPNKTANGQLVIRDSTIDASYD..REQ
 230 FSNISA.DSDLLASVnst..LSHLGRPW--------------------------------..---
 231 ------.--------.....----------------------------------------..---
 232 KCSISA.LN------.....----------------------------------------..---
 233 ------.--------.....----------------------------------------..---
 234 ------.--------.....----------------------------------------..---
 235 NCTIKP.ADDLVSSNytv..KTYXGRPWKEY-----------------------------..---
 236 KCKITA.SSDLAPVKgsv..KTYXGRPWKEY-----------------------------..---
 237 QCTISP.NGNVTA--.....TTYXGRPWKEY-----------------------------..---
 238 GCNIKA.SFDNSSV-.....KSYLGRPW--------------------------------..---
 239 ------.--------.....----------------------------------------..---
 240 ------.--------.....----------------------------------------..---
 241 ------.--------.....----------------------------------------..---
 242 ------.--------.....----------------------------------------..---
 243 ------.--------.....---------PYSR--------------TVVMQSPIGNHIDptGWA
 244 ------.--------.....----------------------------------------..---
 245 ------.--------.....----------------------------------------..---


                  290              300          310         320       3
                   |                |            |           |        
   1 KM.....SGKDKNGNTI..WFNPEDS.....RF...FEYKSYGAGAA..VSKDRRQLTDAQAAEY
   2 EW.....SGE-------..-FALKTL.....YY...GEYMNNGPGAG..TSKRVKWPGYHVITD-
   3 VW.....DGD-------..-FALKTL.....YY...GEYMNKGPGAG..TSKRVKWPGYHILSAA
   4 VW.....DGD-------..-FALKTL.....YY...GEYMNKGPGAG..TSKRVKWPGYHILSAA
   5 EW.....DGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
   6 EW.....DGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
   7 EW.....DGN-------..-FALNTL.....FY...GEHQNSGAGAG..TSGRVKWKGFRVITSA
   8 EW.....DGN-------..-FALNTL.....FY...GEHQNSGAGAG..TSGRVKWKGFRVITSA
   9 EW.....DGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
  10 EW.....DGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHCITD-
  11 EW.....HGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
  12 EW.....HGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHCITD-
  13 EW.....SGS-------..-FALDTL.....TY...REYLNRGGGAG..TANRVKWKGYKVIT--
  14 EW.....NGN-------..-FALNTL.....FY...GEYANTGAGAA..TSGRVKWKGHKVITS-
  15 EW.....HGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
  16 EW.....TGT-------..-FALNTL.....TY...REYSNTGAGAG..TANRVKWRGFKVIT--
  17 EW.....NGN-------..-FALDTL.....FY...GEYANTGAGAP..TSGRVKWKGHKVITS-
  18 EW.....DAQSK-----..-DFLQTL.....YY...GEYMNSGAGAG..TSKRVNWPGYHIIT--
  19 EW.....NGD-------..-FALNSL.....FY...GEYMNYGPGAG..LGSRVKWPGYQVFNES
  20 EW.....NGD-------..-FALSTL.....YY...AEYNNTGSGSS..TTDRVVWPGYHVINS-
  21 EW.....NGD-------..-FALSTL.....YY...AEYNNTGPGSN..TTNRVTWPGYHVINS-
  22 KM.....SGKDKNGNTI..WFNPEDS.....RF...FEYKSYGAGAA..VSKDRRQLTDAQAAEY
  23 KM.....SGKDKNGNTI..WFNPEDS.....RF...FEYKSYGAGAT..VSKDRRQLTDAQAAEY
  24 PW.....QGD-------..-FGLKTL.....YY...AEYSNKGGGAQ..TNARIKWPGYHIIKKE
  25 EW.....DGN-------..-FALKTL.....FY...AEFQNTGPGAS..TSGRVTWPGFRVL---
  26 EW.....DAQSK-----..-DFLQTL.....YY...GEYMNSGAGAG..TSKRVNWPGYHIITS-
  27 EW.....RGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
  28 EW.....NAD-------..-FALDTL.....FY...GEFMNYGPGSG..LSSRVKWPGYHVFNN-
  29 PW.....SGD-------..-FALKTL.....YY...AEHMNTGPGSN..QAQRVKWPGIKKLTPQ
  30 EW.....SGS-------..-FALDTL.....TY...REYLNRGGGAG..TANRVKWKGYKVIT--
  31 EW.....DAASK-----..-DFLQTL.....YY...GEYLNSGAGAG..TSKRVTWPGYHIIK--
  32 EW.....SGD-------..-FALNTL.....YY...AEYMNTGPGSS..TANRVKWRGYHVLTSP
  33 EW.....DAASK-----..-DFLQTL.....YY...GEYLNSGAGAG..TSKRVTWPGYHIIK--
  34 EW.....SGD-------..-FALNTL.....YY...AEYMNTGPGSS..TANRVKWRGYHVLTSP
  35 KW.....KDD-------..-FALETL.....YY...GEYMNEGPGSN..MTNRVQWPGFKRIETV
  36 IW.....DGE-------..-SFHKSC.....RY...VEYNNRGPGAF..ANRRVNWAKVARSAAE
  37 EW.....NGT-------..-IGLDTI.....YY...GEYSNFGPGAN..TNQRVQWLGYNLLN--
  38 IW.....DGE-------..-SFHKSC.....RY...VEYNNRGPGAI..TNRRVNWVKIARSAAE
  39 EW.....NTT-------..-FALDTL.....YY...GEYLNSGPGSG..LGQRVSWPGYRVIN--
  40 IW.....DGE-------..-SFHKSC.....RY...VEYNNRGPGAI..TNRRVNWVKIARSAAE
  41 KW.....NET-------..-FALNTL.....FY...TEYRNRGRGSG..QGRRVRWRGIKRISDR
  42 IW.....DGE-------..-SFHKSC.....RY...VEYNNRGPGAF..ANRRVNWAKVARSAAE
  43 PW.....TGD-------..-SAPDTI.....FY...GEYKNTGPGAS..TKNRVKWKGLRFLS--
  44 PW.....NITN------..-FGRDTS.....YY...AEYQNRGPGAA..LDKRITWKGF------
  45 EW.....QGE-------..-QNHKTA.....KY...IEFNNRGPGAA..TTQRPPWVKVAKSAAE
  46 RW.....QETD------..-FAIDTL.....YY...AEYNNKGSSGD..TTSRVKWPGFKVINKE
  47 PW.....NGD-------..-FALKTL.....YY...AEYNNRGPGAG..TSKRVNWPGFHVIG--
  48 EW.....QGE-------..-KFHLTA.....TY...VEFNNRGPGAN..TAARVPWAKMAKSAAE
  49 PW.....LGD-------..-FGLKTL.....FY...SEVQNTGPGSA..LANRVTWAGIKTLSEE
  50 AW.....SGD-------..-FALSTL.....YY...AEYNNTGPGSD..TTNRVTWPGYHVINAT
  51 EW.....SGS-------..-YALSTL.....YY...GEFMNTGAGAG..TGRRVNWPGFHVLR--
  52 KW.....NGG-------..-EALDTL.....YY...GEYNNNGPGSE..TVKRVNWPGFHIMGYE
  53 EG.....KKD-------..-FALETL.....YY...GEYMNEGPGAN..MAKRVTWPGFRRIENQ
  54 RW.....QETD------..-FAIDTL.....SY...AEYKNDGPSGA..TAARVKWPGFRVLNKE
  55 PW.....SGS-------..-FALSTL.....YY...GEYGNTGAGAS..VSGRVKWPGYHVIKTV
  56 PW.....SGG-------..-FGLKSL.....FY...GEYGNSGPGSS..VSGRVKWSGCHPS---
  57 EW.....FGN-------..-FALDTL.....WY...GEYNNIGPGWR..SSGRVKWPGYHIMDKR
  58 EW.....NGN-------..-FALDTL.....YY...GEYMNSGPGAS..LDRRVKWPGYHVLN--
  59 EW.....QGE-------..-KFHLTA.....TY...VEFNNRGPGAN..PAARVPWAKMAKSAAE
  60 EW.....NGN-------..-FALNTL.....FY...GEYQNTGAGAG..TSGRVKWRGFKVITS-
  61 PW.....MGS-------..-AFKETC.....TY...YEYNNKGPGAD..TNLRVKWHGVKVLTS-
  62 PW.....SSN-------..-FALKTL.....YY...GEFGNSGPGSS..VSGRVSWAGYHPA---
  63 SW.....VSGV------..-DPPASI.....VY...GEYKNTGPGSD..VTQRVKWAGYKP----
  64 PW.....EGE-------..-TGLSTL.....HY...REYQNRGPGAV..TSRRVKWSGFKVMKDP
  65 DW.....DNV-------..-TALSTL.....YY...GEYQNSGPGSG..TENRVDWAGFHVISD-
  66 PM.....VGG-------..-AFKDTC.....TF...YEYNNKGPGAD..TNLRVKWHGVKVLTS-
  67 SW.....VPNV------..-EPPTTI.....FY...AEYQNSGPGAD..VSQRVKWAGYK-----
  68 PW.....SGD-------..-FALKTL.....YY...GESKNTGPGSD..RSQRVSWSSQIPDEHV
  69 PW.....LRGSN-----..-FALNTV.....FY...GEYKNFGPGSS..TRWRVRWKGFHAITS-
  70 VW.....DGD-------..-FALKTL.....YY...GEYMNKGPGAG..TSKRVKWPGYHILSAA
  71 EW.....DGDG------..-GELATL.....FY...GEYRNYGPGAN..IGGRVRWPGYHVIMDA
  72 PW.....MGS-------..-AFKDTC.....TF...YEYNNKGPGAD..TSKRVKWPGVKSISST
  73 --.....----------..-------.....--...---------AD..TSKRVGWKGYHTI---
  74 EW.....NGT-------..-FALDTL.....YY...GEYNNRGPGAN..TSGRVTWPGYRVITN-
  75 PW.....EGE-------..-TGLSTL.....HY...REYQNRGPGAV..TSRRVKWSGFKVMKDP
  76 NW.....GDS-------..-TKEKTV.....TF...GEHKCYGPGAD..YKERVLFGKQLTDSEA
  77 DM.....GDP-------..-KTQRTV.....YY...GEHRCYGPGAN..HSKRVTYAKLLSDVEA
  78 --.....----------..-------.....--...-----------..----------------
  79 --.....----------..-------.....--...-----------..----------------
  80 QW.....GDS-------..-TKENTV.....YY...GEYKCYGPGAD..REQRVEWSKQLSDEEA
  81 --.....----------..-------.....--...-----------..----------------
  82 EN.....LNR-------..-GYDKTV.....FY...GEYKCFGPGSH..LEKRVPYTQDIDKNEV
  83 NF.....NDP-------..-SRDATI.....FY...GEYNCSGPGAD..MSKRAPYVQKLNETQ-
  84 PW.....SGD-------..-FALSTL.....YY...GEFGNSGPGAN..VSSRVPWSRLVPEEHV
  85 VW.....STTQ------..-ANTENV.....TF...AEYGNTGAGAE..--GTRASFSEKLSEPV
  86 AW.....KAK-------..-GQEGHI.....TF...VEFGCTGVGAD..TSKRVPWLTKASEKDV
  87 EW.....STST------..-PNTENV.....TF...VEYGNTGTGAE..--GPRANFSSELTEPI
  88 EN.....KTP-------..-AHDKTV.....FY...GEYKCSGPGSH..KAKRVPFTQDIDDKEA
  89 EN.....KTP-------..-AHDKTV.....FY...GEYKCSGPGSH..KAKRVPFTQDIDDKEA
  90 EN.....RVR-------..-AHDKTV.....FY...GEYMCTGPGSH..KAKRVAHTQDIDNKEA
  91 QW.....GSSD------..-PRTDKV.....TF...GEYGNTGDGAS..--GTRATFAKKLSSAV
  92 AW.....NTGD------..-ARTDHV.....LF...GEYQNTGAGAS..---GKRSFGQTLKAAL
  93 --.....----------..-------.....--...-----------..----------------
  94 NW.....SYH-------..-GSTQNL.....YH...GEYKCHGPGAE..RQKRSDWAKDLTKQEV
  95 EW.....STST------..-PNTEYV.....TF...GEYANTGAGSE..--GTRASFAEKLDAKL
  96 --.....----------..-------.....--...-----------..----------------
  97 --.....----------..-------.....--...-----------..----------------
  98 PW.....DGE-------..-FALSTL.....YY...GEYANTGPGAD..TSKRVNWKGFKVIKD-
  99 EW.....DGN-------..-FALNTL.....FY...GEHQNAGAGAG..TSGRVKWKGFRVITSA
 100 PW.....GPSTAGRPYCssKCAYSAN.....RF...FEYNNTGAGS-..----------------
 101 PW.....NSSTT-----..-GRLSTL.....YY...GEYKNKGPRAN..TSQRV-----------
 102 --.....----------..-------.....--...-----------..----------------
 103 PWa13gnTGSVDDNDEI..QRNLNDT.....NYnrmWEYNNRGVGSK..----------------
 104 PWa13gnTGSVDDNDEI..QRNLNDT.....NYnrmWEYNNRGVGSK..----------------
 105 PW.....GAAATTDRPF..KGNI---.....--...-----------..----------------
 106 AW.....RAK-------..-GNERDL.....TF...VEAGCTGAGAD..TSQRVPWLKKLSLSEV
 107 SW.....HYG-------..-GYEMSF.....TY...AEVECKGAGSD..MSRRVPWIDKLHSFYT
 108 LQ.....DICIQ-----..-------.....--...---NTAGPARDqaVALRVKWPGYHVIT--
 109 --.....----------..-------.....--...-----------..----------------
 110 --.....----------..-------.....--...-----------..----------------
 111 PW.....GVAATTARPF..AGNVD--.....--...-----------..----------------
 112 --.....----------..-------.....--...-----------..----------------
 113 --.....----------..-------.....--...-----------..----------------
 114 --.....----------..-------.....--...-----------..----------------
 115 --.....----------..-------.....--...-----------..----------------
 116 --.....----------..-------.....--...-----------..----------------
 117 --.....----------..-------.....--...-----------..----------------
 118 --.....----------..-------.....--...-----------..----------------
 119 --.....----------..-------.....--...-----------..----------------
 120 EW.....SGE-------..-FALKTL.....YY...GEYMNNGPGAG..TSKRVKWPGYHVITD-
 121 VW.....DGD-------..-FALKTL.....YY...GEYMNKGPGAG..TSKRVKWPGYHILSAA
 122 VW.....DGD-------..-FALKTL.....YY...GEYMNKGPGAG..TSKRVKWPGYHILSAA
 123 EW.....HGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
 124 EW.....HGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHCITD-
 125 EW.....DGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
 126 EW.....DGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
 127 EW.....DGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHCITD-
 128 EW.....DGN-------..-FALNTL.....FY...GEHQNSGAGAG..TSGRVKWKGFRVITSA
 129 EW.....DGN-------..-FALNTL.....FY...GEHQNSGAGAG..TSGRVKWKGFRVITSA
 130 EW.....HGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
 131 EW.....DAQSK-----..-DFLQTL.....YY...GEYMNSGAGAG..TSKRVNWPGYHIITS-
 132 EW.....DGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
 133 EW.....NGN-------..-FALNTL.....FY...GEYANTGAGAA..TSGRVKWKGHKVITS-
 134 EW.....SGS-------..-FALDTL.....TY...REYLNRGGGAG..TANRVKWKGYKVIT--
 135 EW.....TGT-------..-FALNTL.....TY...REYSNTGAGAG..TANRVKWRGFKVITA-
 136 EW.....NGN-------..-FALDTL.....FY...GEYANTGAGAP..TSGRVKWKGHKVITS-
 137 EW.....DAASK-----..-DFLQTL.....YY...GEYLNSGAGAG..TSKRVTWPGYHIIK--
 138 EW.....DAASK-----..-DFLQTL.....YY...GEYLNSGAGAG..TSKRVTWPGYHIIK--
 139 EW.....SGS-------..-FALDTL.....TY...REYLNRGGGAG..TANRVKWKGYKVIT--
 140 EW.....RGD-------..-FALKTL.....YY...GEFMNNGPGAG..TSKRVKWPGYHVITD-
 141 EW.....NGD-------..-FALSTL.....YY...AEYNNTGSGSS..TTDRVVWPGYHVINS-
 142 EW.....DGN-------..-FALKTL.....FY...AEFQNTGPGAS..TSGRVTWPGFRVLG--
 143 EW.....NGD-------..-FALNSL.....FY...GEYMNYGPGAG..LGSRVKWPGYQVFNES
 144 EW.....SGD-------..-FALNTL.....YY...AEYMNTGPGSS..TANRVKWRGYHVLTSP
 145 EW.....NGD-------..-FALSTL.....YY...AEYNNTGPGSN..TTNRVTWPGYHVINS-
 146 EW.....SGD-------..-FALNTL.....YY...AEYMNTGPGSS..TANRVKWRGYHVLTSP
 147 PW.....QGD-------..-FGLKTL.....YY...AEYSNKGGGAQ..TNARIKWPGYHIIKKE
 148 EW.....DAQSK-----..-DFLQTL.....YY...GEYMNSGAGAG..TSKRVNWPGYHIITS-
 149 EW.....NAD-------..-FALDTL.....FY...GEFMNYGPGSG..LSSRVKWPGYHVFN--
 150 EW.....NGN-------..-FALDTL.....YY...GEYMNSGPGAS..LDRRVKWPGYHVLN--
 151 KM.....SGKDKNGNTI..WFNPEDS.....RF...FEYKSYGAGAA..VSKDRRQLTDAQAAEY
 152 KM.....SGKDKNGNTI..WFNPEDS.....RF...FEYKSYGAGAT..VSKDRRQLTDAQAAEY
 153 EW.....FGN-------..-FALDTL.....WY...GEYNNIGPGWR..SSGRVKWPGYHIMDKR
 154 PW.....SGD-------..-FALKTL.....YY...AEHMNTGPGSN..QAQRVKWPGIKKLTPQ
 155 AW.....SGD-------..-FALSTL.....YY...AEYNNTGPGSD..TTNRVTWPGYHVINA-
 156 PW.....LGD-------..-FGLKTL.....FY...SEVQNTGPGSA..LANRVTWAGIKTLSEE
 157 KW.....KDD-------..-FALETL.....YY...GEYMNEGPGSN..MTNRVQWPGFKRIETV
 158 IW.....DGE-------..-SFHKSC.....RY...VEYNNRGPGAF..ANRRVNWAKVARSAAE
 159 PW.....NGD-------..-FALKTL.....YY...AEYNNRGPGAG..TSKRVNWPGFHVIG--
 160 KW.....NGG-------..-EALDTL.....YY...GEYNNNGPGSE..TVKRVNWPGFHIMGYE
 161 EW.....NGT-------..-IGLDTI.....YY...GEYSNFGPGAN..TNQRVQWLGYNLLN--
 162 IW.....DGE-------..-SFHKSC.....RY...VEYNNRGPGAI..TNRRVNWVKIARSAAE
 163 IW.....DGE-------..-SFHKSC.....RY...VEYNNRGPGAI..TNRRVNWVKIARSAAE
 164 IW.....DGE-------..-SFHKSC.....RY...VEYNNRGPGAF..ANRRVNWAKVARSAAE
 165 EW.....NTT-------..-FALDTL.....YY...GEYLNSGPGSG..LGQRVSWPGYRVINS-
 166 EW.....QGE-------..-QNHKTA.....KY...IEFNNRGPGAA..TTQRPPWVKVAKSAAE
 167 PW.....NITN------..-FGRDTS.....YY...AEYQNRGPGAA..LDKRITWKGF------
 168 KW.....NET-------..-FALNTL.....FY...TEYRNRGRGSG..QGRRVRWRGIKRISDR
 169 PW.....TGD-------..-SAPDTI.....FY...GEYKNTGPGAS..TKNRVKWKGLRFL---
 170 EW.....QGE-------..-KFHLTA.....TY...VEFNNRGPGAN..TAARVPWAKMAKSAAE
 171 EW.....SGS-------..-YALSTL.....YY...GEFMNTGAGAG..TGRRVNWPGFHVLR--
 172 RW.....QETD------..-FAIDTL.....SY...AEYKNDGPSGA..TAARVKWPGFRVLNKE
 173 PW.....SGS-------..-FALSTL.....YY...GEYGNTGAGAS..VSGRVKWPGYHVIKTV
 174 RW.....QETD------..-FAIDTL.....YY...AEYNNKGSSGD..TTSRVKWPGFKVINKE
 175 PW.....MGS-------..-AFKDTC.....TF...YEYNNKGPGAD..TSKRVKWPGVKSISST
 176 PW.....SGG-------..-FGLKSL.....FY...GEYGNSGPGSS..VSGRVKWSGCHPS---
 177 EW.....NGN-------..-FALNTL.....FY...GEYQNTGAGAG..TSGRVKWRGFKVITSA
 178 PW.....SSN-------..-FALKTL.....YY...GEFGNSGPGSS..VSGRVSWAGYHP----
 179 EW.....QGE-------..-KFHLTA.....TY...VEFNNRGPGAN..PAARVPWAKMAKSAAE
 180 PW.....SGD-------..-FALKTL.....YY...GESKNTGPGSD..RSQRVSWSSQIPDEH-
 181 SW.....VSGV------..-DPPASI.....VY...GEYKNTGPGSD..VTQRVKWAGYK-----
 182 PW.....MGS-------..-AFKETC.....TY...YEYNNKGPGAD..TNLRVKWHGVKVLT--
 183 EG.....KKD-------..-FALETL.....YY...GEYMNEGPGAN..MAKRVTWPGFRRIEN-
 184 PW.....EGE-------..-TGLSTL.....HY...REYQNRGPGAV..TSRRVKWSGFKVMKDP
 185 SW.....VPNV------..-EPPTTI.....FY...AEYQNSGPGAD..VSQRVKWAGYK-----
 186 PM.....VGG-------..-AFKDTC.....TF...YEYNNKGPGAD..TNLRVKWHGVKVLT--
 187 DW.....DNV-------..-TALSTL.....YY...GEYQNSGPGSG..TENRVDWAGFHVISD-
 188 PW.....LRGSN-----..-FALNTV.....FY...GEYKNFGPGSS..TRWRVRWKGFHAITS-
 189 EW.....DGDG------..-GELATL.....FY...GEYRNYGPGAN..IGGRVRWPGYHVIMD-
 190 VW.....DGD-------..-FALKTL.....YY...GEYMNKGPGAG..TSKRVKWPGYHILSAA
 191 --.....----------..-------.....--...---------AD..TSKRVGWKGYHTIT--
 192 PW.....EGE-------..-TGLSTL.....HY...REYQNRGPGAV..TSRRVKWSGFKVMKDP
 193 EW.....NGT-------..-FALDTL.....YY...GEYNNRGPGAN..TSGRVTWPGYRVITN-
 194 PW.....SGD-------..-FALSTL.....YY...GEFGNSGPGAN..VSSRVPWSRLVPEEHV
 195 DM.....GDP-------..-KTQRTV.....YY...GEHRCYGPGAN..HSKRVTYAKLLSDVEA
 196 --.....----------..-------.....--...-----------..----------------
 197 --.....----------..-------.....--...-----------..----------------
 198 EN.....LNR-------..-GYDKTV.....FY...GEYKCFGPGSH..LEKRVPYTQDIDKNEV
 199 --.....----------..-------.....--...-----------..----------------
 200 NF.....NDP-------..-SRDATI.....FY...GEYNCSGPGAD..MSKRAPYVQKLNETQV
 201 QW.....GDS-------..-TKENTV.....YY...GEYKCYGPGAD..REQRVEWSKQLSDEEA
 202 NW.....GDS-------..-TKEKTV.....TF...GEHKCYGPGAD..YKERVLFGKQLTDSEA
 203 NW.....SYH-------..-GSTQNL.....YH...GEYKCHGPGAE..RQKRSDWAKDLTKQEV
 204 EN.....KTP-------..-AHDKTV.....FY...GEYKCSGPGSH..KAKRVPFTQDIDDKEA
 205 AW.....KAK-------..-GQEGHI.....TF...VEFGCTGVGAD..TSKRVPWLTKASEKDV
 206 EW.....STST------..-PNTENV.....TF...VEYGNTGTGAE..-GPRANFSSELTEPIT
 207 EN.....KTP-------..-AHDKTV.....FY...GEYKCSGPGSH..KAKRVPFTQDIDDKEA
 208 EN.....RVR-------..-AHDKTV.....FY...GEYMCTGPGSH..KAKRVAHTQDIDNKEA
 209 --.....----------..-------.....--...-----------..----------------
 210 VW.....STTQ------..-ANTENV.....TF...AEYGNTGAGAE..-GTRASFSEKLSEPVA
 211 PW.....DGE-------..-FALSTL.....YY...GEYANTGPGAD..TSKRVNWKGFKVIKD-
 212 QW.....GSSD------..-PRTDKV.....TF...GEYGNTGDGAS..-GTRATFAKKLSSAVS
 213 --.....----------..-------.....--...-----------..----------------
 214 --.....----------..-------.....--...-----------..----------------
 215 EW.....STST------..-PNTEYV.....TF...GEYANTGAGSE..-GTRASFAEKLDAKLT
 216 EW.....DGN-------..-FALNTL.....FY...GEHQNAGAGAG..TSGRVKWKGFRVITSA
 217 PW.....GPSTAGRPYCssKCAYSAN.....RF...FEYNNTGAGS-..----------------
 218 PW.....NSSTT-----..-GRLSTL.....YY...GEYKNKGPRAN..TSQRV-----------
 219 --.....----------..-------.....--...-----------..----------------
 220 AW.....NTGD------..-ARTDHV.....LF...GEYQNTGAGAS..GK---RSFGQTL----
 221 PW.....ADAVISNRPF..AGNTGSVd16ynRM...WEYNNRGVGS-..----------------
 222 PW.....ADAVISNRPF..AGNTGSVd16ynRM...WEYNNRGVGS-..----------------
 223 PW.....GAAATTDRPF..KGN----.....--...-----------..----------------
 224 LQ.....DICIQNTA--..-------.....--...------GPARDqaVALRVKWPGYHVITD-
 225 AW.....RAK-------..-GNERDL.....TF...VEAGCTGAGAD..TSQRVPWLKKLSLSEV
 226 SW.....HYG-------..-GYEMSF.....TY...AEVECKGAGSD..MSRRVPWIDKLHSFYT
 227 --.....----------..-------.....--...-----------..----------------
 228 --.....----------..-------.....--...-----------..----------------
 229 PW.....GVAATTARPF..AGNVDSAr....--...-----------..----------------
 230 --.....----------..-------.....--...-----------..----------------
 231 --.....----------..-------.....--...-----------..----------------
 232 --.....----------..-------.....--...-----------..----------------
 233 --.....----------..-------.....--...-----------..----------------
 234 --.....----------..-------.....--...-----------..----------------
 235 --.....----------..-------.....--...-----------..----------------
 236 --.....----------..-------.....--...-----------..----------------
 237 --.....----------..-------.....--...-----------..----------------
 238 --.....----------..-------.....--...-----------..----------------
 239 --.....----------..-------.....--...-----------..----------------
 240 --.....----------..-------.....--...-----------..----------------
 241 --.....----------..-------.....--...-----------..----------------
 242 --.....----------..-------.....--...-----------..----------------
 243 EW.....DDASK-----..-AFLKTL.....YY...GEYLNSGPGAG..TAKRVNWPGYHVLNTA
 244 --.....----------..-------.....--...-----------..----------------
 245 --.....----------..-------.....--...-----------..----------------


      30       340  
      |         |  
   1 TQSKVLGDWTPTLP
   2 --------------
   3 E-------------
   4 E-------------
   5 --------------
   6 --------------
   7 --------------
   8 --------------
   9 --------------
  10 --------------
  11 --------------
  12 --------------
  13 --------------
  14 --------------
  15 --------------
  16 --------------
  17 --------------
  18 --------------
  19 T-------------
  20 --------------
  21 --------------
  22 TQSKVLGDWTPTLP
  23 TQSKVLGDWTPTLP
  24 EA------------
  25 --------------
  26 --------------
  27 --------------
  28 --------------
  29 DALLYTGD------
  30 --------------
  31 --------------
  32 --------------
  33 --------------
  34 --------------
  35 --------------
  36 VNGFTAANWLGP--
  37 --------------
  38 VNDFTVANWLGP--
  39 --------------
  40 VNDFTVANWLGP--
  41 A-------------
  42 VNGFTAANWLGP--
  43 --------------
  44 --------------
  45 VETYTVANWVG---
  46 E-------------
  47 --------------
  48 VERFTVANWLT---
  49 DIL-----------
  50 --------------
  51 --------------
  52 --------------
  53 --------------
  54 EA------------
  55 --------------
  56 --------------
  57 T-------------
  58 --------------
  59 VERFTVANWLT---
  60 --------------
  61 --------------
  62 --------------
  63 --------------
  64 --------------
  65 --------------
  66 --------------
  67 --------------
  68 --------------
  69 --------------
  70 E-------------
  71 --------------
  72 EAAAF---------
  73 --------------
  74 --------------
  75 --------------
  76 SS------------
  77 APF-----------
  78 --------------
  79 --------------
  80 TVF-----------
  81 --------------
  82 TPFLTLG-------
  83 --------------
  84 S-------------
  85 AISTILGSDWAQW-
  86 LQFT----------
  87 TISWLLGSDWEDW-
  88 NCFLSLG-------
  89 NRFLSLG-------
  90 SQFLTLG-------
  91 SISTVLGSSYKNW-
  92 SITDILGSNYKDW-
  93 --------------
  94 ESFLS---------
  95 TITDILGSDYTSW-
  96 --------------
  97 --------------
  98 --------------
  99 --------------
 100 --------------
 101 --------------
 102 --------------
 103 --------------
 104 --------------
 105 --------------
 106 DGF-----------
 107 KQQFSISNF-----
 108 --------------
 109 --------------
 110 --------------
 111 --------------
 112 --------------
 113 --------------
 114 --------------
 115 --------------
 116 --------------
 117 --------------
 118 --------------
 119 --------------
 120 --------------
 121 E-------------
 122 E-------------
 123 --------------
 124 --------------
 125 --------------
 126 --------------
 127 --------------
 128 --------------
 129 --------------
 130 --------------
 131 --------------
 132 --------------
 133 --------------
 134 --------------
 135 --------------
 136 --------------
 137 --------------
 138 --------------
 139 --------------
 140 --------------
 141 --------------
 142 --------------
 143 T-------------
 144 --------------
 145 --------------
 146 --------------
 147 E-------------
 148 --------------
 149 --------------
 150 --------------
 151 TQSKVLGDWTPTLP
 152 TQSKVLGDWTPTLP
 153 T-------------
 154 DALLYTGD------
 155 --------------
 156 D-------------
 157 --------------
 158 VNGFTAANWLGP--
 159 --------------
 160 --------------
 161 --------------
 162 VNDFTVANWLGP--
 163 VNDFTVANWLGP--
 164 VNGFTAANWLGP--
 165 --------------
 166 VETYTVANWVG---
 167 --------------
 168 --------------
 169 --------------
 170 VERFTVANWLT---
 171 --------------
 172 E-------------
 173 --------------
 174 --------------
 175 E-------------
 176 --------------
 177 --------------
 178 --------------
 179 VERFTVANWLT---
 180 --------------
 181 --------------
 182 --------------
 183 --------------
 184 --------------
 185 --------------
 186 --------------
 187 --------------
 188 --------------
 189 --------------
 190 E-------------
 191 --------------
 192 --------------
 193 --------------
 194 --------------
 195 APF-----------
 196 --------------
 197 --------------
 198 TPFLTLG-------
 199 --------------
 200 --------------
 201 TVF-----------
 202 SSF-----------
 203 ESFLS---------
 204 NCFLSLG-------
 205 LQFT----------
 206 ISWLLGSDWEDW--
 207 NRFLSLG-------
 208 SQFLTLG-------
 209 --------------
 210 ISTILGSDWAQW--
 211 --------------
 212 ISTVLGSSY-----
 213 --------------
 214 --------------
 215 ITDILGSDYTS---
 216 --------------
 217 --------------
 218 --------------
 219 --------------
 220 --------------
 221 --------------
 222 --------------
 223 --------------
 224 --------------
 225 DGF-----------
 226 KQQFSISNF-----
 227 --------------
 228 --------------
 229 --------------
 230 --------------
 231 --------------
 232 --------------
 233 --------------
 234 --------------
 235 --------------
 236 --------------
 237 --------------
 238 --------------
 239 --------------
 240 --------------
 241 --------------
 242 --------------
 243 E-------------
 244 --------------
 245 --------------