Entrez protein Query

Other Formats: [FASTA Format] [Graphical View]
Links: [2 medline links] [373 protein neighbors] 

LOCUS       2134996      2677 aa                              06-SEP-1996
DEFINITION  desmoplakin I - human.
ACCESSION   2134996
PID         g2134996
DBSOURCE    PIR: locus A38194
            summary: #length 2677 #molecular-weight 309986 #checksum 6195.
            genetic: #gene GDB:DSP ##cross-references GDB:126564 #map_position
            6pter-6p21.
            includes: desmoplakin II.
            PIR dates: 04-Mar-1993 #sequence_revision 03-May-1996 #text_change
            06-Sep-1996.
KEYWORDS    alternative splicing; cytoskeleton; heptad repeat.
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Mammalia; Eutheria; Primates; Catarrhini; Hominidae;
            Homo.
REFERENCE   1  (residues 1 to 2677)
  AUTHORS   Green,K.J., Parry,D.A., Steinert,P.M., Virata,M.L., Wagner,R.M.,
            Angst,B.D. and Nilles,L.A.
  TITLE     Structure of the human desmoplakins. Implications for function in
            the desmosomal plaque
  JOURNAL   J. Biol. Chem. 265 (5), 2603-2612 (1990)
  MEDLINE   90153880
  REMARK    Erratum:[J Biol Chem 1990 Jul 5;265(19):11406-7]
REFERENCE   2  (residues 1 to 2677)
  AUTHORS   Virata,M.L., Wagner,R.M., Parry,D.A. and Green,K.J.
  TITLE     Molecular structure of the human desmoplakin I and II amino
            terminus
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89 (2), 544-548 (1992)
  MEDLINE   92115697
COMMENT     On May 30, 1997 this sequence version replaced gi:284064.
            Desmoplakins I and II, products of single gene, are major proteins
            of the innermost region of the desmosomal plaque and help to anchor
            intermediate filaments to the cell surface.
FEATURES             Location/Qualifiers
     source          1..2677
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
     Protein         1..2677
                     /product="desmoplakin I"
     Region          1..1000
                     /note="desmoplakin II"
                     /region_name="product"
     Region          1..2677
                     /note="desmoplakin I"
                     /region_name="product"
     Region          1600..2677
                     /note="desmoplakin II"
                     /region_name="product"
ORIGIN      
        1 mrqqraemdm vawgvdlasv eqhinshrgi hnsigdyrwq ldkikadlre ksaiyqleee
       61 yenllkasfe rmdhlrqlqn iiqatsreim windceeeel lydwsdkntn iaqkqeafsi
      121 rmsqlevkek elnklkqesd qlvlnqhpas dkieaymdtl qtqwswilqi tkcidvhlke
      181 naayfqffee aqsteaylkg lqdsirkkyp cdknmplqhl leqikeleke rekileykrq
      241 vqnlvnkskk ivqlkprnpd yrsnkpiilr alcdykqdqk ivhkgdecil kdnnerskwy
      301 vtgpggvdml vpsvgliipp pnplavdlsc kieqyyeail alwnqlyinm kslvswhycm
      361 idiekiramt iaklktmrqe dymktiadle lhyqefirns qgsemfgddd krkiqsqftd
      421 aqkhyqtlvi qlpgypqhqt vttteithhg tcqdvnhnkv ietnrendkq etwmlmelqk
      481 irrqiehceg rmtlknlpla dqgsshhitv kinelksvqn dsqaiaevln qlkdmlanfr
      541 gsekycylqn evfglfqkle ningvtdgyl nslctvrall qailqtedml kvyearltee
      601 etvcldldkv eayrcglkki kndlnlkksl latmktelqk aqqihsqtsq qyplydldlg
      661 kfgekvtqlt drwqridkqi dfrlwdlekq ikqlrnyrdn yqafckwlyd rkrrqdsles
      721 mkfgdsntvm rflneqknlh seisgkrdks eevqkiaelc ansikdyelq lasytsglet
      781 llnipikrtm iqspsgvilq eaadvharyi elltrsgdyy rflsemlksl edlklkntki
      841 evleeelrla rdansencnk nkfldqnlqk yqaecsqfka klasleelkr qaeldgksak
      901 qnldkcygqi kelnekitrl tyeiedekrr rksvedrfdq qkndydqlqk arqcekenlg
      961 wqklesekai kekeyeierl rvllqeegtr kreyenelak vrnhyneems nlrnkyetei
     1021 nitkttikei smqkeddskn lrnqldrlsr enrdlkdeiv rlndsilqat eqrrraeena
     1081 lqqkacgsei mqkkqhleie lkqvmqqrse dnarhkqsle eaaktiqdkn keierlkaef
     1141 qeeakrrwey enelskvrnn ydeeiislkn qfeteinitk ttihqltmqk eedtsgyraq
     1201 idnltrenrs lseeikrlkn tltqttenlr rveediqqqk atgsevsqrk qqlevelrqv
     1261 tqmrteesvr ykqslddaak tiqdknkeie rlkqlidket ndrkcleden arlqrvqydl
     1321 qkanssatet inklkvqeqe ltrlridyer vsqertvkdq ditrfqnslk elqlqkqkve
     1381 eelnrlkrta sedsckrkkl eeelegmrrs lkeqaikitn ltqqleqasi vkkrseddlr
     1441 qqrdvldghl rekqrtqeel rrlsseveal rrqllqeqes vkqahlrneh fqkaiedksr
     1501 slneskieie rlqsltenlt kehlmleeel rnlrleyddl rrgrseadsd knatilelrs
     1561 qlqisnnrtl elqglindlq rerenlrqei ekfqkqalea snriqesknq ctqvvqeres
     1621 llvkikvleq dkarlqrled elnrakstle aetrvkqrle cekqqiqndl nqwktqysrk
     1681 eeairkiese rekserekns lrseierlqa eikrieercr rkledstret qsqletersr
     1741 yqreidklrq rpygshretq tecewtvdts klvfdglrkk vtamqlyecq lidkttldkl
     1801 lkgkksveev aseiqpflrg agsiagasas pkekyslvea krkklispes tvmlleaqaa
     1861 tggiidphrn ekltvdsaia rdlidfddrq qiyaaekait gfddpfsgkt vsvseaikkn
     1921 lidretgmrl leaqiasggv vdpvnsvflp kdvalargli drdlyrslnd prdsqknfvd
     1981 pvtkkkvsyv qlkercriep htgllllsvq krsmsfqgir qpvtvtelvd sgilrpstvn
     2041 elesgqisyd evgerikdfl qgssciagiy nettkqklgi yeamkiglvr pgtalellea
     2101 qaatgfivdp vsnlrlpvee aykrglvgie fkekllsaer avtgyndpet gniislfqam
     2161 nkeliekghg irlleaqiat ggiidpkesh rlpvdiaykr gyfneelsei lsdpsddtkg
     2221 ffdpnteenl tylqlkerci kdeetglcll plkekkkqvq tsqkntlrkr rvvivdpetn
     2281 kemsvqeayk kglidyetfk elceqecewe eititgsdgs trvvlvdrkt gsqydiqdai
     2341 dkglvdrkff dqyrsgslsl tqfadmislk ngvgtsssmg sgvsddvfss srhesvskis
     2401 tissvrnlti rsssfsdtle esspiaaifd tenlekisit egiergivds itgqrlleaq
     2461 actggiihpt tgqklslqda vsqgvidqdm atsvkpaqka figfegvkgk kkmsaaeavk
     2521 ekwlpyeagq rflefqyltg glvdpevhgr isteeairkg fidgraaqrl qdtssyakil
     2581 tcpktklkis ykdainrsmv editglrlle aasvsskglp spynmssapg srsgsrsgsr
     2641 sgsrsgsrsg srrgsfdatg nssysysysf ssssigh
//

the above report in format