CASP3 Target T0079

1. Protein Name: MarA
2. Organism Name: E. coli
3. Number of amino acids (approx): 129
4. Accession number: P27246
5. Sequence Database: Swiss-prot
6. Amino acid sequence: MTMSRRNTDA
ITIHSILDWI
EDNLESPLSL
EKVSERSGYS
KWHLQRMFKK
ETGHSLGQYI
RSRKMTEIAQ
KLKESNEPIL
YLAERYGFES
QQTLTRTFKN
YFDVPPHKYR
MTNMQGESRF
LHPLNHYNS
7. Homologous Sequence of known structure: no
8. Current state of the experimental work: Protein supply: Over-expressed in E. coli by Bob Martin in NIH
Crystal: diffracts to 2.3 Angstrom in synchrotron
Structre of MarA, a transcriptional activator, in complex
with DNA is solved by the MAD method.
It will be published in the PNAS in the early of September.
9. Interpretable map?: yes
10. Estimated date of chain tracing completion: done
11. Estimated date of public release of structure: In Press, PNAS (Early September)
12. Additional Information: 1. This protein, MarA, belongs to an AraC family of
transcriptional regulatory proteins.

2. There are now more than 100 proteins of high sequence
homology with this AraC family.
13. Name: unavailable until after public release of structure