SWISS-PROT: P27246
ID   MARA_ECOLI     STANDARD;      PRT;   129 AA.
AC   P27246;
DT   01-AUG-1992 (REL. 23, CREATED)
DT   01-AUG-1992 (REL. 23, LAST SEQUENCE UPDATE)
DT   01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE)
DE   MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN MARA.
GN   MARA.
OS   ESCHERICHIA COLI.
OC   PROKARYOTA; GRACILICUTES; SCOTOBACTERIA; FACULTATIVELY ANAEROBIC RODS;
OC   ENTEROBACTERIACEAE.
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE; 93186717. [NCBI, ExPASy, Japan]
RA   COHEN S.P., HAECHLER H., LEVY S.B.;
RL   J. BACTERIOL. 175:1484-1492(1993).
RN   [2]
RP   SEQUENCE FROM N.A.
RC   STRAIN=K12;
RX   MEDLINE; 93259932. [NCBI, ExPASy, Japan]
RA   GAMBINO L., GRACHECK S., MILLER P.F.;
RL   J. BACTERIOL. 175:2888-2894(1993).
RN   [3]
RP   SEQUENCE FROM N.A.
RC   STRAIN=K12 / MG1655;
RA   BLATTNER F.R., PLUNKETT G. III, MAYHEW G.F., PERNA N.T., GLASNER F.D.;
RL   SUBMITTED (JAN-1997) TO EMBL/GENBANK/DDBJ DATA BANKS.
RN   [4]
RP   SEQUENCE FROM N.A.
RC   STRAIN=K12;
RX   MEDLINE; 97251357. [NCBI, ExPASy, Japan]
RA   AIBA H., BABA T., FUJITA K., HAYASHI K., INADA T., ISONO K.,
RA   ITOH T., KASAI H., KASHIMOTO K., KIMURA S., KITAKAWA M.,
RA   KITAGAWA M., MAKINO K., MIKI T., MIZOBUCHI K., MORI H., MORI T.,
RA   MOTOMURA K., NAKADE S., NAKAMURA Y., NASHIMOTO H., NISHIO Y.,
RA   OSHIMA T., SAITO N., SAMPEI G., SEKI Y., SIVASUNDARAM S.,
RA   TAGAMI H., TAKEDA J., TAKEMOTO K., TAKEUCHI Y., WADA C.,
RA   YAMAMOTO Y., HORIUCHI T.;
RL   DNA RES. 3:363-377(1996).
CC   -!- FUNCTION: MAY BE A TRANSCRIPTIONAL ACTIVATOR OF GENES INVOLVED IN
CC       THE MULTIPLE ANTIBIOTIC RESISTANCE (MAR) PHENOTYPE. IT CAN ALSO
CC       ACTIVATE GENES SUCH AS SODA, ZWF AND MICF.
CC   -!- INDUCTION: BY VARIOUS ANTIBIOTICS OR BY SODIUM SALICYLATE.
CC   -!- SIMILARITY: BELONGS TO THE ARAC/XYLS FAMILY OF TRANSCRIPTIONAL
CC       REGULATORS.
CC   -!- CAUTION: IT IS UNCERTAIN WHETHER MET-1 OR MET-3 IS THE INITIATOR.
DR   EMBL; M96235; G146732; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   EMBL; L06966; G146729; ALT_INIT. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   EMBL; AE000250; G1787811; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   EMBL; D90796; G1742513; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   EMBL; D90797; G1742527; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   PIR; B47072; B47072.
DR   ECOGENE; EG11434; MARA.
DR   ECOCYC; EG11434; MARA.
DR   PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR   DOMO; P27246.
DR   PRODOM [Domain structure / List of seq. sharing at least 1 domain]
DR   PROTOMAP; P27246.
DR   SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW   ANTIBIOTIC RESISTANCE; TRANSCRIPTION REGULATION; ACTIVATOR;
KW   DNA-BINDING.
FT   DNA_BIND     30     49       H-T-H MOTIF (POTENTIAL).
SQ   SEQUENCE   129 AA;  15416 MW;  5CC38FB0 CRC32;
     MTMSRRNTDA ITIHSILDWI EDNLESPLSL EKVSERSGYS KWHLQRMFKK ETGHSLGQYI
     RSRKMTEIAQ KLKESNEPIL YLAERYGFES QQTLTRTFKN YFDVPPHKYR MTNMQGESRF
     LHPLNHYNS
//

Direct WU-BLAST submission at EMBNet-CH (Lausanne, Switzerland)

Direct BLAST submission at NCBI (Bethesda, USA)

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